IMP: Integrative Multi-species Prediction

Drosophila melanogaster

15 known processes

CG4933 (Dmel_CG4933)

CG4933 gene product from transcript CG4933-RA

(Aliases: Dmel\CG4933)

FLYBASE: FBgn0036615
Entrez: 39811
UniProtKB: Q9VV41

Process Predictions
Disease Predictions

CG4933 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
positive regulation of gene expression	GO:0010628	290	0.212
rna processing	GO:0006396	147	0.101
negative regulation of cellular metabolic process	GO:0031324	382	0.099
positive regulation of rna metabolic process	GO:0051254	271	0.098
growth	GO:0040007	359	0.092
protein localization	GO:0008104	284	0.077
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.075
cellular catabolic process	GO:0044248	372	0.075
negative regulation of gene expression	GO:0010629	387	0.072
regulation of organelle organization	GO:0033043	196	0.071
chromatin organization	GO:0006325	207	0.070
establishment of localization in cell	GO:0051649	402	0.069
negative regulation of transcription dna templated	GO:0045892	237	0.068
small molecule metabolic process	GO:0044281	305	0.067
positive regulation of macromolecule metabolic process	GO:0010604	405	0.065
transcription from rna polymerase ii promoter	GO:0006366	368	0.065
positive regulation of rna biosynthetic process	GO:1902680	266	0.061
response to organic substance	GO:0010033	284	0.057
endocytosis	GO:0006897	310	0.054
regulation of cell cycle	GO:0051726	291	0.053
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.053
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.052
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.050
negative regulation of rna biosynthetic process	GO:1902679	240	0.050
proteolysis	GO:0006508	192	0.048
positive regulation of transcription dna templated	GO:0045893	266	0.048
dna dependent dna replication	GO:0006261	17	0.047
nucleobase containing small molecule metabolic process	GO:0055086	174	0.046
catabolic process	GO:0009056	409	0.045
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.045
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.042
vesicle mediated transport	GO:0016192	381	0.042
peptidyl lysine modification	GO:0018205	57	0.040
negative regulation of cellular biosynthetic process	GO:0031327	277	0.040
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.037
single organism catabolic process	GO:0044712	228	0.037
protein modification process	GO:0036211	438	0.037
negative regulation of cell cycle	GO:0045786	116	0.036
macromolecular complex assembly	GO:0065003	256	0.036
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.036
positive regulation of biosynthetic process	GO:0009891	316	0.035
nuclear division	GO:0000280	332	0.035
cell division	GO:0051301	248	0.035
chromatin modification	GO:0016568	147	0.035
single organism membrane organization	GO:0044802	93	0.034
response to oxidative stress	GO:0006979	86	0.033
cellular response to external stimulus	GO:0071496	66	0.033
chromosome organization	GO:0051276	360	0.033
peptidyl amino acid modification	GO:0018193	105	0.032
positive regulation of multicellular organismal process	GO:0051240	143	0.032
nucleotide metabolic process	GO:0009117	161	0.031
regulation of cell cycle process	GO:0010564	181	0.030
organophosphate metabolic process	GO:0019637	195	0.030
carboxylic acid metabolic process	GO:0019752	92	0.030
organonitrogen compound metabolic process	GO:1901564	318	0.029
cellular response to dna damage stimulus	GO:0006974	223	0.029
organic substance catabolic process	GO:1901575	308	0.029
nucleoside phosphate metabolic process	GO:0006753	162	0.029
chromosome segregation	GO:0007059	157	0.028
cellular amino acid metabolic process	GO:0006520	61	0.027
purine ribonucleotide metabolic process	GO:0009150	145	0.027
lateral inhibition	GO:0046331	206	0.027
cellular protein localization	GO:0034613	160	0.025
taxis	GO:0042330	304	0.025
single organism behavior	GO:0044708	391	0.024
developmental growth	GO:0048589	280	0.024
dna repair	GO:0006281	54	0.024
dna metabolic process	GO:0006259	227	0.023
response to oxygen containing compound	GO:1901700	200	0.023
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.022
carbohydrate derivative metabolic process	GO:1901135	217	0.022
positive regulation of developmental process	GO:0051094	143	0.022
homeostatic process	GO:0042592	199	0.022
organic substance transport	GO:0071702	257	0.022
trna modification	GO:0006400	2	0.022
intracellular transport	GO:0046907	228	0.022
cell death	GO:0008219	279	0.022
negative regulation of cell cycle process	GO:0010948	109	0.022
organelle fission	GO:0048285	340	0.022
cellular protein modification process	GO:0006464	438	0.021
cytoplasmic transport	GO:0016482	130	0.021
cellular macromolecular complex assembly	GO:0034622	153	0.021
programmed cell death	GO:0012501	257	0.020
multicellular organismal aging	GO:0010259	140	0.020
positive regulation of response to stimulus	GO:0048584	323	0.020
mitotic cell cycle phase transition	GO:0044772	138	0.020
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.020
mitotic nuclear division	GO:0007067	213	0.020
response to abiotic stimulus	GO:0009628	341	0.019
mrna metabolic process	GO:0016071	124	0.019
purine nucleotide metabolic process	GO:0006163	146	0.019
regulation of mitotic cell cycle	GO:0007346	190	0.019
cellular nitrogen compound catabolic process	GO:0044270	165	0.019
phagocytosis	GO:0006909	215	0.019
regulation of cellular protein metabolic process	GO:0032268	243	0.018
organophosphate biosynthetic process	GO:0090407	46	0.018
positive regulation of signal transduction	GO:0009967	223	0.018
regulation of localization	GO:0032879	275	0.018
ribonucleotide metabolic process	GO:0009259	145	0.018
regulation of response to stress	GO:0080134	200	0.018
protein processing	GO:0016485	68	0.018
regulation of molecular function	GO:0065009	217	0.018
aging	GO:0007568	143	0.018
negative regulation of cell communication	GO:0010648	223	0.018
negative regulation of biosynthetic process	GO:0009890	277	0.018
apoptotic process	GO:0006915	159	0.018
macromolecule catabolic process	GO:0009057	161	0.018
dendrite morphogenesis	GO:0048813	199	0.018
dna replication	GO:0006260	48	0.018
dendrite development	GO:0016358	204	0.018
regulation of cellular component biogenesis	GO:0044087	201	0.018
positive regulation of cell communication	GO:0010647	250	0.017
regulation of cellular response to stress	GO:0080135	89	0.017
regulation of cytoskeleton organization	GO:0051493	89	0.017
phosphorylation	GO:0016310	294	0.017
anatomical structure homeostasis	GO:0060249	97	0.017
establishment of protein localization	GO:0045184	163	0.017
positive regulation of intracellular signal transduction	GO:1902533	116	0.016
response to biotic stimulus	GO:0009607	294	0.016
negative regulation of rna metabolic process	GO:0051253	251	0.016
regulation of growth	GO:0040008	233	0.016
oxoacid metabolic process	GO:0043436	103	0.016
single organism biosynthetic process	GO:0044711	206	0.016
organic acid metabolic process	GO:0006082	103	0.016
posttranscriptional gene silencing	GO:0016441	46	0.016
aromatic compound catabolic process	GO:0019439	166	0.016
regulation of hydrolase activity	GO:0051336	97	0.015
cellular macromolecule catabolic process	GO:0044265	136	0.015
negative regulation of mitotic cell cycle	GO:0045930	109	0.015
trna processing	GO:0008033	3	0.015
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.015
regulation of catalytic activity	GO:0050790	185	0.015
regulation of developmental growth	GO:0048638	174	0.015
heterocycle catabolic process	GO:0046700	166	0.014
purine containing compound metabolic process	GO:0072521	155	0.014
ribose phosphate metabolic process	GO:0019693	145	0.014
cell cycle phase transition	GO:0044770	140	0.014
body morphogenesis	GO:0010171	2	0.014
cell cycle checkpoint	GO:0000075	95	0.014
ion transmembrane transport	GO:0034220	122	0.014
purine ribonucleoside metabolic process	GO:0046128	127	0.014
positive regulation of signaling	GO:0023056	243	0.014
ribonucleoside metabolic process	GO:0009119	127	0.013
regulation of cell death	GO:0010941	173	0.013
adult behavior	GO:0030534	137	0.013
camera type eye development	GO:0043010	4	0.013
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.013
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.013
sister chromatid segregation	GO:0000819	92	0.013
regulation of catabolic process	GO:0009894	170	0.013
regulation of protein metabolic process	GO:0051246	256	0.013
regulation of cell cycle phase transition	GO:1901987	130	0.013
negative regulation of cellular component organization	GO:0051129	108	0.012
protein complex assembly	GO:0006461	200	0.012
positive regulation of growth	GO:0045927	75	0.012
regulation of multicellular organismal development	GO:2000026	414	0.012
protein maturation	GO:0051604	71	0.012
eye development	GO:0001654	323	0.012
regulation of transport	GO:0051049	181	0.012
spindle organization	GO:0007051	253	0.012
determination of adult lifespan	GO:0008340	137	0.012
negative regulation of developmental process	GO:0051093	201	0.012
positive regulation of phosphorus metabolic process	GO:0010562	139	0.012
organic cyclic compound catabolic process	GO:1901361	168	0.012
embryo development ending in birth or egg hatching	GO:0009792	152	0.012
response to other organism	GO:0051707	293	0.011
cellular response to chemical stimulus	GO:0070887	199	0.011
covalent chromatin modification	GO:0016569	106	0.011
morphogenesis of an epithelium	GO:0002009	276	0.011
positive regulation of cellular biosynthetic process	GO:0031328	316	0.011
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.011
internal peptidyl lysine acetylation	GO:0018393	38	0.011
death	GO:0016265	284	0.011
amine metabolic process	GO:0009308	12	0.011
regulation of tor signaling	GO:0032006	21	0.011
neurological system process	GO:0050877	358	0.011
intracellular signal transduction	GO:0035556	300	0.011
multicellular organism growth	GO:0035264	46	0.010
nucleobase containing compound catabolic process	GO:0034655	165	0.010
regulation of multi organism process	GO:0043900	131	0.010
cellular macromolecule localization	GO:0070727	220	0.010
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.010
protein transport	GO:0015031	155	0.010
cellular amine metabolic process	GO:0044106	12	0.010
organelle assembly	GO:0070925	198	0.010
locomotory behavior	GO:0007626	176	0.010
organonitrogen compound catabolic process	GO:1901565	128	0.010
regulation of intracellular signal transduction	GO:1902531	236	0.010
single organism intracellular transport	GO:1902582	207	0.010
regulation of apoptotic process	GO:0042981	130	0.010
tor signaling	GO:0031929	32	0.010
gene silencing	GO:0016458	138	0.010
retina development in camera type eye	GO:0060041	4	0.010

CG4933 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.028
	nervous system disease	DOID:863	0	0.016

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