Drosophila melanogaster

124 known processes

fj (Dmel_CG10917)

four-jointed

(Aliases: Fj,Dmel\CG10917,CG10917)

fj biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
imaginal disc derived appendage morphogenesisGO:00351143951.000
imaginal disc derived leg morphogenesisGO:0007480800.997
imaginal disc derived appendage developmentGO:00487373990.996
leg disc developmentGO:0035218920.994
leg disc morphogenesisGO:0007478800.993
equator specificationGO:004531740.993
appendage morphogenesisGO:00351073970.993
wing disc morphogenesisGO:00074723440.992
appendage developmentGO:00487364010.991
imaginal disc derived wing hair organizationGO:0035317450.989
post embryonic appendage morphogenesisGO:00351203850.977
imaginal disc derived wing morphogenesisGO:00074763370.975
imaginal disc derived leg segmentationGO:0036011260.970
compound eye morphogenesisGO:00017452490.940
establishment of epithelial cell polarityGO:0090162130.879
establishment of tissue polarityGO:0007164870.846
establishment of imaginal disc derived wing hair orientationGO:0001737240.844
compound eye developmentGO:00487493070.836
establishment of epithelial cell apical basal polarityGO:0045198100.820
sensory organ morphogenesisGO:00905962600.756
Mouse
imaginal disc derived leg joint morphogenesisGO:0016348150.729
imaginal disc derived wing vein specificationGO:0007474480.711
establishment of ommatidial planar polarityGO:0042067490.706
negative regulation of response to stimulusGO:00485852580.705
regionalizationGO:00030024160.704
eye morphogenesisGO:00485922600.696
Mouse
regulation of multicellular organismal developmentGO:20000264140.693
establishment of body hair or bristle planar orientationGO:004810460.669
establishment of planar polarityGO:0001736870.617
eye antennal disc morphogenesisGO:0007455340.601
establishment of body hair planar orientationGO:004810510.588
digestive system developmentGO:00551231490.573
embryonic pattern specificationGO:00098801740.565
r3 r4 cell differentiationGO:0048056120.558
blastoderm segmentationGO:00073501590.557
enzyme linked receptor protein signaling pathwayGO:00071671790.542
establishment or maintenance of monopolar cell polarityGO:0061339150.523
eye developmentGO:00016543230.519
Mouse
notch signaling pathwayGO:00072191200.519
epithelial cell differentiationGO:00308553220.515
cell cell adhesion mediated by cadherinGO:004433160.515
hair cell differentiationGO:0035315470.510
axis specificationGO:00097981670.479
cell migration involved in gastrulationGO:004207490.478
segmentationGO:00352822070.475
morphogenesis of a polarized epitheliumGO:0001738930.466
anterior posterior axis specificationGO:00099481090.442
anterior posterior pattern specificationGO:00099521360.442
regulation of cell developmentGO:00602842150.440
negative regulation of erbb signaling pathwayGO:1901185290.434
wing disc pattern formationGO:0035222660.434
hippo signalingGO:0035329200.417
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.414
limb morphogenesisGO:003510810.406
negative regulation of developmental processGO:00510932010.404
regulation of tube size open tracheal systemGO:0035151430.383
morphogenesis of an epitheliumGO:00020092760.372
columnar cuboidal epithelial cell developmentGO:00020662490.371
regulation of organ morphogenesisGO:2000027780.370
kidney epithelium developmentGO:007207330.367
establishment or maintenance of epithelial cell apical basal polarityGO:0045197240.332
formation of anatomical boundaryGO:0048859370.324
regulation of neurogenesisGO:00507671580.315
imaginal disc derived wing hair site selectionGO:003532040.295
establishment of apical basal cell polarityGO:0035089120.290
appendage segmentationGO:0035285260.283
negative regulation of imaginal disc growthGO:004557180.272
embryonic organ developmentGO:0048568500.271
kidney developmentGO:000182230.266
gastrulationGO:0007369700.266
tissue morphogenesisGO:00487292970.261
nephron morphogenesisGO:007202830.261
imaginal disc pattern formationGO:0007447910.254
convergent extension involved in gastrulationGO:006002720.244
imaginal disc derived wing vein morphogenesisGO:0008586440.236
epithelial cell developmentGO:00020642740.234
compound eye photoreceptor cell differentiationGO:00017511400.233
regulation of notch signaling pathwayGO:00085931000.233
cellular protein modification processGO:00064644380.229
open tracheal system developmentGO:00074242040.226
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.215
embryonic morphogenesisGO:00485982060.211
regulation of imaginal disc growthGO:0045570260.210
kidney morphogenesisGO:006099330.200
wing disc anterior posterior pattern formationGO:004810050.197
cell proliferationGO:00082832990.189
dorsal ventral pattern formationGO:00099531330.187
negative regulation of signal transductionGO:00099682060.187
chaeta developmentGO:0022416970.185
negative regulation of cell communicationGO:00106482230.183
non sensory hair organizationGO:0035316470.178
eye antennal disc developmentGO:0035214600.175
nephron developmentGO:007200630.173
imaginal disc growthGO:0007446370.171
negative regulation of notch signaling pathwayGO:0045746410.171
establishment or maintenance of apical basal cell polarityGO:0035088340.165
positive regulation of signal transductionGO:00099672230.165
notum cell fate specificationGO:003531050.162
establishment of proximal distal cell polarityGO:002260640.161
regulation of cell differentiationGO:00455953020.159
epidermal growth factor receptor signaling pathwayGO:0007173580.158
ovarian follicle cell developmentGO:00307072480.150
convergent extensionGO:006002620.146
tube morphogenesisGO:00352391910.145
hematopoietic or lymphoid organ developmentGO:0048534570.142
organ growthGO:0035265560.142
regulation of nervous system developmentGO:00519602480.141
regulation of erbb signaling pathwayGO:1901184420.141
establishment of cell polarityGO:0030010400.137
somatic muscle developmentGO:0007525660.134
establishment of monopolar cell polarityGO:0061162150.130
nephron tubule morphogenesisGO:007207830.129
forebrain developmentGO:003090020.128
epidermis developmentGO:0008544650.127
embryonic axis specificationGO:00005781070.117
tripartite regional subdivisionGO:00073511030.116
digestive tract developmentGO:00485651490.115
eye photoreceptor cell differentiationGO:00017541450.110
positive regulation of response to stimulusGO:00485843230.109
anterior posterior pattern specification imaginal discGO:0007448160.109
myotube cell developmentGO:001490430.105
positive regulation of nucleobase containing compound metabolic processGO:00459353320.102
regulation of heart morphogenesisGO:200082630.101
erbb signaling pathwayGO:0038127580.100
anterior posterior axis specification embryoGO:00085951030.100
developmental growthGO:00485892800.095
regulation of tube architecture open tracheal systemGO:0035152680.095
eggshell formationGO:00307031050.095
terminal region determinationGO:0007362250.094
positive regulation of macromolecule metabolic processGO:00106044050.090
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.089
protein phosphorylationGO:00064681690.085
muscle organ developmentGO:00075171270.084
cell migrationGO:00164772380.083
positive regulation of cell communicationGO:00106472500.083
eye photoreceptor cell fate commitmentGO:0042706370.082
zygotic determination of anterior posterior axis embryoGO:0007354270.081
imaginal disc derived wing margin morphogenesisGO:0008587410.081
organic substance transportGO:00717022570.081
regulation of protein modification processGO:00313991120.081
regulation of catalytic activityGO:00507901850.079
chorion containing eggshell formationGO:00073041050.078
axon developmentGO:00615642970.077
head developmentGO:00603221350.073
phosphorylationGO:00163102940.073
heart developmentGO:0007507820.072
regulation of organ growthGO:0046620420.072
feeding behaviorGO:0007631500.071
negative regulation of developmental growthGO:0048640640.068
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.068
tissue migrationGO:00901301550.068
camera type eye photoreceptor cell differentiationGO:006021920.067
cell surface receptor signaling pathway involved in heart developmentGO:006131130.066
skeletal muscle fiber developmentGO:004874130.066
single organism nuclear importGO:1902593510.066
endoderm formationGO:000170630.063
glycoprotein metabolic processGO:0009100410.062
negative regulation of gene expressionGO:00106293870.062
ommatidial rotationGO:0016318200.062
positive regulation of nitrogen compound metabolic processGO:00511733540.061
determination of left right symmetryGO:000736890.061
protein modification processGO:00362114380.060
regulation of apoptotic processGO:00429811300.060
protein glycosylationGO:0006486320.060
nephron tubule developmentGO:007208030.059
apoptotic process involved in morphogenesisGO:006056130.058
glycoprotein biosynthetic processGO:0009101410.058
regulation of tube length open tracheal systemGO:0035159240.058
establishment or maintenance of cell polarityGO:00071631670.057
regulation of epithelial cell differentiationGO:003085640.056
nephron epithelium morphogenesisGO:007208830.056
epidermal cell differentiationGO:0009913510.056
carbohydrate derivative metabolic processGO:19011352170.055
regulation of cell proliferationGO:00421271630.054
cell cell adhesionGO:0098609260.053
hindbrain developmentGO:003090220.053
negative regulation of multicellular organismal processGO:00512411420.053
mesoderm formationGO:0001707210.051
regulation of anatomical structure morphogenesisGO:00226032420.050
epithelium migrationGO:00901321480.048
wing and notum subfield formationGO:0035309130.047
negative regulation of signalingGO:00230572190.047
photoreceptor cell fate commitmentGO:0046552410.047
negative regulation of cellular metabolic processGO:00313243820.047
regulation of imaginal disc derived wing sizeGO:0044719200.044
torso signaling pathwayGO:0008293210.044
mesoderm developmentGO:0007498780.044
compound eye photoreceptor fate commitmentGO:0001752360.044
leg disc proximal distal pattern formationGO:000747990.044
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.043
tube developmentGO:00352952440.043
cell motilityGO:00488702510.042
dorsal ventral axis specificationGO:0009950660.041
muscle cell fate commitmentGO:0042693140.040
regulation of organ formationGO:000315630.040
compound eye photoreceptor developmentGO:0042051780.040
apical constrictionGO:0003383180.040
nephron epithelium developmentGO:007200930.040
limb developmentGO:006017310.039
regulation of programmed cell deathGO:00430671520.039
regulation of cell cycleGO:00517262910.039
outflow tract morphogenesisGO:000315140.038
drug transportGO:001589320.037
negative regulation of canonical wnt signaling pathwayGO:009009060.037
positive regulation of pathway restricted smad protein phosphorylationGO:001086210.037
regulation of r7 cell differentiationGO:0045676150.036
determination of dorsal ventral asymmetryGO:004826230.036
regulation of localizationGO:00328792750.036
r3 r4 cell fate commitmentGO:0007464100.036
compound eye retinal cell programmed cell deathGO:0046667230.035
peptidyl threonine phosphorylationGO:001810720.035
muscle structure developmentGO:00610612240.035
single organismal cell cell adhesionGO:0016337450.034
connective tissue developmentGO:006144830.034
dendrite self avoidanceGO:007059380.034
response to extracellular stimulusGO:00099911160.034
proximal distal pattern formationGO:0009954150.034
enteroendocrine cell differentiationGO:003588310.034
chemotaxisGO:00069352490.034
regulation of tube sizeGO:0035150460.034
positive regulation of signalingGO:00230562430.034
female genitalia developmentGO:003054060.034
gland developmentGO:00487321910.034
single organism cell adhesionGO:0098602470.033
positive regulation of catabolic processGO:00098961050.033
regulation of compound eye retinal cell programmed cell deathGO:0046669180.033
defense responseGO:00069523000.033
protein targeting to nucleusGO:0044744510.032
cell adhesionGO:00071551360.032
regulation of hippo signalingGO:0035330140.032
negative regulation of autophagyGO:0010507160.032
axonogenesisGO:00074092900.032
cell maturationGO:00484691440.031
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.031
regulation of dendrite morphogenesisGO:0048814280.030
positive regulation of transcription dna templatedGO:00458932660.030
synaptic target recognitionGO:0008039450.030
response to organic substanceGO:00100332840.030
regulation of canonical wnt signaling pathwayGO:0060828150.030
regulation of embryonic developmentGO:0045995680.030
cardiac muscle tissue developmentGO:004873890.030
neurological system processGO:00508773580.029
spindle localizationGO:0051653220.029
anterior malpighian tubule developmentGO:0061327120.029
purine containing compound catabolic processGO:00725231120.029
neuron fate commitmentGO:0048663500.029
negative regulation of organ growthGO:0046621150.028
regulation of synapse assemblyGO:0051963940.028
protein localizationGO:00081042840.028
smad protein import into nucleusGO:0007184110.028
establishment or maintenance of bipolar cell polarityGO:0061245340.028
developmental maturationGO:00217001720.027
specification of symmetryGO:0009799130.027
carbohydrate derivative biosynthetic processGO:1901137850.027
spinal cord developmentGO:002151010.027
hindgut morphogenesisGO:0007442580.026
epithelial cell migrationGO:00106311480.026
muscle cell fate specificationGO:004269470.026
pattern recognition receptor signaling pathwayGO:000222120.026
wnt signaling pathwayGO:0016055980.025
determination of bilateral symmetryGO:0009855130.025
proximal distal pattern formation imaginal discGO:0007449110.025
ribose phosphate metabolic processGO:00196931450.025
anterior head developmentGO:009706530.025
regulation of wnt signaling pathwayGO:0030111680.025
wing disc dorsal ventral pattern formationGO:0048190470.025
transcription from rna polymerase ii promoterGO:00063663680.025
regulation of cellular amine metabolic processGO:003323830.025
dendrite morphogenesisGO:00488131990.024
localization of cellGO:00516742570.024
negative regulation of cell deathGO:0060548810.024
positive regulation of cellular protein catabolic processGO:1903364240.024
nucleocytoplasmic transportGO:0006913720.024
genital disc sexually dimorphic developmentGO:003526340.024
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.024
carbohydrate derivative catabolic processGO:19011361180.023
camera type eye developmentGO:004301040.023
Mouse
morphogenesis of a branching epitheliumGO:0061138450.023
peripheral nervous system developmentGO:0007422520.023
determination of ventral identityGO:004826410.023
ameboidal type cell migrationGO:00016671510.022
maternal specification of dorsal ventral axis oocyte soma encodedGO:000731330.022
protein modification by small protein conjugationGO:0032446790.022
digestive tract morphogenesisGO:00485461270.022
agingGO:00075681430.022
spiracle morphogenesis open tracheal systemGO:0035277220.021
central nervous system developmentGO:00074172010.021
cell fate specification involved in pattern specificationGO:006057380.021
regulation of cell proliferation involved in imaginal disc derived wing morphogenesisGO:009025620.021
lymph gland developmentGO:0048542280.021
response to growth factorGO:0070848310.021
regulation of cell deathGO:00109411730.021
intracellular signal transductionGO:00355563000.020
cytoskeleton dependent cytokinesisGO:0061640810.020
embryonic hemopoiesisGO:0035162260.020
regulation of growthGO:00400082330.020
digestive tract mesoderm developmentGO:000750250.020
ion homeostasisGO:0050801550.020
positive regulation of intracellular signal transductionGO:19025331160.020
growthGO:00400073590.020
negative regulation of neuron deathGO:1901215180.020
sensory neuron axon guidanceGO:009737420.019
organonitrogen compound metabolic processGO:19015643180.019
response to abiotic stimulusGO:00096283410.019
brain developmentGO:00074201200.019
protein targetingGO:0006605640.019
negative regulation of protein phosphorylationGO:0001933170.019
regulation of establishment of planar polarityGO:0090175220.019
regulation of molecular functionGO:00650092170.019
positive regulation of biosynthetic processGO:00098913160.018
genital disc pattern formationGO:003522180.018
gland morphogenesisGO:00226121450.018
negative regulation of programmed cell deathGO:0043069720.018
negative regulation of cell differentiationGO:00455961430.018
intracellular protein transportGO:00068861040.018
pharynx developmentGO:006046510.018
neural retina developmentGO:000340740.018
Mouse
epithelial cell migration open tracheal systemGO:0007427320.018
cell cell junction organizationGO:0045216550.018
fusion cell fate specificationGO:003515640.018
retinal ganglion cell axon guidanceGO:0031290120.018
regulation of pathway restricted smad protein phosphorylationGO:006039310.018
germ line stem cell maintenanceGO:0030718500.018
apposition of dorsal and ventral imaginal disc derived wing surfacesGO:0007475150.017
dendrite developmentGO:00163582040.017
oxoacid metabolic processGO:00434361030.017
ventral midline developmentGO:000741890.017
negative regulation of phosphate metabolic processGO:0045936450.017
cardiovascular system developmentGO:0072358820.017
protein ubiquitinationGO:0016567700.017
renal filtration cell differentiationGO:0061318120.017
regulation of cellular amino acid metabolic processGO:000652100.017
cell divisionGO:00513012480.017
regulation of neuroblast proliferationGO:1902692340.016
cell recognitionGO:00080371020.016
regulation of neural precursor cell proliferationGO:2000177350.016
regulation of cell shapeGO:00083601130.016
detection of stimulusGO:00516061560.016
positive regulation of gene expressionGO:00106282900.016
cellular macromolecule localizationGO:00707272200.016
wnt signaling pathway planar cell polarity pathwayGO:006007160.016
dorsal ventral pattern formation imaginal discGO:0007450510.016
wound healingGO:0042060750.016
leg disc pattern formationGO:0035223110.015
nuclear importGO:0051170510.015
stem cell differentiationGO:00488631170.015
nucleobase containing small molecule metabolic processGO:00550861740.015
organic substance catabolic processGO:19015753080.015
mesodermal cell fate specificationGO:000750120.015
establishment of protein localization to organelleGO:0072594620.015
second mitotic wave involved in compound eye morphogenesisGO:001633070.015
retinal cone cell differentiationGO:004267020.015
amine metabolic processGO:0009308120.015
negative regulation of heart induction by canonical wnt signaling pathwayGO:000313630.015
embryonic heart tube developmentGO:0035050220.015
purine nucleotide metabolic processGO:00061631460.015
positive regulation of cell differentiationGO:0045597640.015
stem cell proliferationGO:0072089880.015
endocytosisGO:00068973100.015
regulation of compound eye photoreceptor developmentGO:0045314120.014
eye photoreceptor cell developmentGO:0042462810.014
immune response regulating signaling pathwayGO:000276420.014
synapse assemblyGO:00074161430.014
regulation of epithelial cell proliferationGO:005067840.014
positive regulation of rna metabolic processGO:00512542710.014
myotube differentiationGO:0014902460.014
pericardium morphogenesisGO:000334420.014
histolysisGO:00075591020.014
cellular response to growth factor stimulusGO:0071363300.014
positive regulation of notch signaling pathwayGO:0045747340.014
optic lobe placode formationGO:000174440.014
actin filament based processGO:00300292200.014
regulation of execution phase of apoptosisGO:190011750.014
response to biotic stimulusGO:00096072940.014
negative regulation of biosynthetic processGO:00098902770.014
negative regulation of nitrogen compound metabolic processGO:00511722650.013
instar larval developmentGO:0002168550.013
purine ribonucleotide metabolic processGO:00091501450.013
muscle tissue developmentGO:0060537300.013
protein importGO:0017038550.013
ion transportGO:00068111450.013
regulation of hydrolase activityGO:0051336970.013
regulation of cell fate specificationGO:0042659270.013
positive regulation of protein catabolic processGO:0045732340.013
embryonic foregut morphogenesisGO:004861730.013
erk1 and erk2 cascadeGO:0070371390.013
embryonic organ morphogenesisGO:004856250.013
urogenital system developmentGO:0001655720.013
immune system processGO:00023763470.013
cellular response to chemical stimulusGO:00708871990.013
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.013
negative regulation of nervous system developmentGO:0051961920.013
positive regulation of phosphorus metabolic processGO:00105621390.013
positive regulation of nf kappab import into nucleusGO:004234610.013
positive regulation of catalytic activityGO:00430851180.013
skeletal muscle organ developmentGO:0060538480.013
cell fate specificationGO:0001708710.013
posttranscriptional regulation of gene expressionGO:00106081450.013
reproductive structure developmentGO:0048608740.013
cell fate commitment involved in pattern specificationGO:0060581310.012
positive regulation of nervous system developmentGO:0051962690.012
compound eye cone cell differentiationGO:0042675130.012
spinal cord dorsal ventral patterningGO:002151310.012
regulation of cellular protein metabolic processGO:00322682430.012
epithelial tube morphogenesisGO:0060562880.012
sex differentiationGO:0007548810.012
deathGO:00162652840.012
specification of organ identityGO:001009230.012
regulation of nf kappab import into nucleusGO:004234510.012
cellular catabolic processGO:00442483720.012
phagocytosisGO:00069092150.012
circulatory system developmentGO:0072359820.012
regulation of anatomical structure sizeGO:00900661630.012
response to fungusGO:0009620500.012
establishment of mitotic spindle orientationGO:0000132130.012
negative regulation of rna metabolic processGO:00512532510.012
protein modification by small protein conjugation or removalGO:00706471060.012
negative regulation of cellular protein metabolic processGO:0032269850.012
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589810.011
negative regulation of cellular biosynthetic processGO:00313272770.011
cellular response to fibroblast growth factor stimulusGO:0044344100.011
epithelial cell morphogenesisGO:0003382250.011
positive regulation of proteolysisGO:0045862520.011
negative regulation of receptor activityGO:200027230.011
actin cytoskeleton organizationGO:00300362060.011
regulation of necrotic cell deathGO:001093910.011
stem cell fate commitmentGO:0048865250.011
respiratory system developmentGO:00605412130.011
negative regulation of cell fate specificationGO:0009996150.011
immune system developmentGO:0002520570.011
purine ribonucleoside catabolic processGO:00461301120.011
negative regulation of apoptotic processGO:0043066630.011
stem cell maintenanceGO:0019827670.011
negative regulation of protein modification processGO:0031400290.011
regulation of ras gtpase activityGO:0032318380.011
axon guidanceGO:00074112330.011
organ formationGO:0048645390.011
establishment of spindle localizationGO:0051293220.011
cell deathGO:00082192790.011
embryonic development via the syncytial blastodermGO:00017001480.011
multicellular organismal homeostasisGO:0048871410.011
protein o linked glycosylationGO:0006493110.011
regulation of protein phosphorylationGO:0001932640.011
negative regulation of hormone biosynthetic processGO:003235310.011
negative regulation of cell fate commitmentGO:0010454170.011
regulation of protein catabolic processGO:0042176550.011
protein localization to nucleusGO:0034504550.011
learning or memoryGO:00076111410.010
cell junction organizationGO:0034330570.010
mitotic nuclear divisionGO:00070672130.010
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.010
regulation of transforming growth factor beta receptor signaling pathwayGO:001701560.010
sensory perception of mechanical stimulusGO:0050954720.010
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.010
nuclear transportGO:0051169720.010
meiotic cell cycle phase transitionGO:004477140.010
dephosphorylationGO:0016311510.010
pathway restricted smad protein phosphorylationGO:006038910.010
determination of imaginal disc primordiumGO:0007445110.010
reproductive system developmentGO:0061458740.010
ubiquitin dependent protein catabolic processGO:0006511780.010
intracellular mrna localization involved in pattern specification processGO:0060810560.010

fj disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:128700.027
disease of anatomical entityDOID:700.027
tetralogy of fallotDOID:641900.027
heart diseaseDOID:11400.027
congenital heart diseaseDOID:168200.027
sensory system diseaseDOID:005015500.012
nervous system diseaseDOID:86300.012
inherited metabolic disorderDOID:65500.011
disease of metabolismDOID:001466700.011