Drosophila melanogaster

83 known processes

Cortactin (Dmel_CG3637)

CG3637 gene product from transcript CG3637-RA

(Aliases: Dmel\CG3637,cortactin,CG3637)

Cortactin biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ovarian follicle cell migrationGO:00072971211.000
epithelial cell migrationGO:00106311480.999
epithelium migrationGO:00901321480.999
border follicle cell migrationGO:00072981130.994
ameboidal type cell migrationGO:00016671510.994
tissue migrationGO:00901301550.991
columnar cuboidal epithelial cell developmentGO:00020662490.989
epithelial cell developmentGO:00020642740.985
columnar cuboidal epithelial cell differentiationGO:00020652560.984
cell motilityGO:00488702510.957
cell migrationGO:00164772380.955
ovarian follicle cell developmentGO:00307072480.951
localization of cellGO:00516742570.820
small molecule metabolic processGO:00442813050.820
actin cytoskeleton organizationGO:00300362060.761
actin filament based processGO:00300292200.652
single organism cellular localizationGO:19025801800.512
embryonic morphogenesisGO:00485982060.479
regulation of actin filament polymerizationGO:0030833250.468
epithelial cell differentiationGO:00308553220.409
negative regulation of actin filament depolymerizationGO:003083520.392
actin filament polymerizationGO:0030041270.375
regulation of actin filament based processGO:0032970420.369
regulation of actin cytoskeleton organizationGO:0032956420.347
female germline ring canal formationGO:000730190.320
carboxylic acid metabolic processGO:0019752920.318
regulation of cellular amino acid metabolic processGO:000652100.294
nucleobase containing small molecule metabolic processGO:00550861740.293
cell proliferationGO:00082832990.290
actomyosin structure organizationGO:0031032560.276
regulation of actin polymerization or depolymerizationGO:0008064270.272
regulation of actin filament lengthGO:0030832270.263
regulation of cytoskeleton organizationGO:0051493890.259
positive regulation of cellular component biogenesisGO:0044089800.252
Fly
response to external biotic stimulusGO:00432072930.223
negative regulation of response to stimulusGO:00485852580.202
actin filament organizationGO:00070151260.196
negative regulation of multicellular organismal processGO:00512411420.169
regulation of cellular component biogenesisGO:00440872010.163
Fly
small gtpase mediated signal transductionGO:0007264880.162
intracellular transportGO:00469072280.158
protein polymerizationGO:0051258420.156
cytokinesisGO:0000910900.150
response to biotic stimulusGO:00096072940.150
regulation of vesicle mediated transportGO:0060627590.143
positive regulation of macromolecule metabolic processGO:00106044050.140
actin filament cappingGO:005169320.138
pseudocleavage involved in syncytial blastoderm formationGO:003058990.136
regulation of protein polymerizationGO:0032271280.136
nucleoside phosphate metabolic processGO:00067531620.129
regulation of cellular component sizeGO:0032535980.129
negative regulation of actin filament polymerizationGO:003083770.126
positive regulation of response to stimulusGO:00485843230.122
positive regulation of multicellular organismal processGO:00512401430.119
Fly
nucleotide metabolic processGO:00091171610.119
positive regulation of cellular component organizationGO:00511301560.119
organelle localizationGO:00516401480.116
organic acid metabolic processGO:00060821030.113
negative regulation of signalingGO:00230572190.112
sensory organ morphogenesisGO:00905962600.111
response to other organismGO:00517072930.110
nucleotide catabolic processGO:00091661090.109
ras protein signal transductionGO:0007265880.109
regulation of immune system processGO:00026821760.107
immune responseGO:00069552460.105
antimicrobial humoral responseGO:0019730990.104
actin filament bundle organizationGO:0061572280.104
regulation of immune responseGO:00507761180.104
purine nucleoside triphosphate metabolic processGO:00091441190.102
asymmetric neuroblast divisionGO:0055059330.102
regulation of cellular amine metabolic processGO:003323830.101
oxoacid metabolic processGO:00434361030.100
epidermal growth factor receptor signaling pathwayGO:0007173580.100
protein complex assemblyGO:00064612000.100
neurological system processGO:00508773580.098
compound eye developmentGO:00487493070.098
regulation of phosphate metabolic processGO:00192202100.096
heterocycle catabolic processGO:00467001660.094
negative regulation of cellular metabolic processGO:00313243820.088
meiotic cytokinesisGO:0033206330.087
actin polymerization or depolymerizationGO:0008154310.087
regulation of organelle organizationGO:00330431960.083
protein complex biogenesisGO:00702712010.082
tube developmentGO:00352952440.082
negative regulation of protein polymerizationGO:003227270.081
regulation of cell deathGO:00109411730.081
regulation of growthGO:00400082330.079
Fly
establishment or maintenance of cell polarityGO:00071631670.079
positive regulation of signal transductionGO:00099672230.077
vesicle mediated transportGO:00161923810.077
organic substance transportGO:00717022570.076
malpighian tubule developmentGO:0072002640.075
muscle cell differentiationGO:00426921030.075
negative regulation of cell communicationGO:00106482230.074
immune system processGO:00023763470.073
regulation of actin filament depolymerizationGO:003083430.070
actin filament depolymerizationGO:003004250.070
embryo development ending in birth or egg hatchingGO:00097921520.068
regulation of endocytosisGO:0030100370.065
establishment of planar polarityGO:0001736870.064
g protein coupled receptor signaling pathwayGO:00071861360.064
cell divisionGO:00513012480.064
digestive tract morphogenesisGO:00485461270.063
response to lipopolysaccharideGO:003249640.063
regulation of protein metabolic processGO:00512462560.062
enzyme linked receptor protein signaling pathwayGO:00071671790.061
eye morphogenesisGO:00485922600.061
germarium derived egg chamber formationGO:00072931010.060
arp2 3 complex mediated actin nucleationGO:003431430.060
cytoskeleton dependent cytokinesisGO:0061640810.060
single organism intracellular transportGO:19025822070.060
intracellular signal transductionGO:00355563000.059
regulation of phosphorus metabolic processGO:00511742100.058
morphogenesis of follicular epitheliumGO:0016333360.058
regulation of transportGO:00510491810.058
cortical actin cytoskeleton organizationGO:0030866240.058
negative regulation of nitrogen compound metabolic processGO:00511722650.058
ion transportGO:00068111450.057
eye developmentGO:00016543230.055
muscle structure developmentGO:00610612240.055
positive regulation of cell migrationGO:003033520.055
sensory perceptionGO:00076001960.055
negative regulation of developmental processGO:00510932010.054
cellular ketone metabolic processGO:0042180240.054
central nervous system developmentGO:00074172010.053
peptidyl tyrosine phosphorylationGO:0018108240.052
negative regulation of signal transductionGO:00099682060.051
circulatory system processGO:0003013370.051
negative regulation of growthGO:0045926840.050
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.050
cellular macromolecular complex assemblyGO:00346221530.050
negative regulation of protein metabolic processGO:0051248850.049
body morphogenesisGO:001017120.049
carbohydrate derivative metabolic processGO:19011352170.048
cellular protein complex assemblyGO:0043623710.048
regulation of small gtpase mediated signal transductionGO:0051056930.047
aromatic compound catabolic processGO:00194391660.047
positive regulation of transportGO:0051050920.047
single organism biosynthetic processGO:00447112060.046
regulation of cell projection assemblyGO:0060491300.046
organic cyclic compound catabolic processGO:19013611680.046
mitotic cytokinesisGO:0000281500.046
respiratory system developmentGO:00605412130.045
peptidyl tyrosine modificationGO:0018212240.045
regulation of proteolysisGO:0030162870.045
regulation of cellular ketone metabolic processGO:001056530.045
gastrulationGO:0007369700.045
cell projection assemblyGO:0030031940.045
regulation of cell motilityGO:2000145230.045
muscle system processGO:0003012210.044
sensory perception of mechanical stimulusGO:0050954720.044
purine nucleoside triphosphate catabolic processGO:00091461080.044
regulation of catalytic activityGO:00507901850.044
amine metabolic processGO:0009308120.044
endocytosisGO:00068973100.044
deathGO:00162652840.044
regulation of protein complex assemblyGO:0043254420.044
positive regulation of rna biosynthetic processGO:19026802660.044
stem cell proliferationGO:0072089880.043
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.043
purine containing compound catabolic processGO:00725231120.042
negative regulation of cellular biosynthetic processGO:00313272770.041
purine ribonucleoside triphosphate catabolic processGO:00092071080.041
cell deathGO:00082192790.041
developmental growthGO:00485892800.040
Fly
striated muscle cell differentiationGO:0051146900.040
organophosphate metabolic processGO:00196371950.040
growthGO:00400073590.039
Fly
negative regulation of gene expressionGO:00106293870.039
photoreceptor cell differentiationGO:00465301700.039
regulation of intracellular signal transductionGO:19025312360.039
ribonucleoside triphosphate metabolic processGO:00091991190.039
cellular response to chemical stimulusGO:00708871990.038
anatomical structure homeostasisGO:0060249970.038
positive regulation of immune system processGO:0002684680.037
organelle fissionGO:00482853400.037
organic substance catabolic processGO:19015753080.037
nucleoside triphosphate metabolic processGO:00091411200.037
transition metal ion homeostasisGO:0055076170.037
guanosine containing compound catabolic processGO:1901069740.037
purine ribonucleotide catabolic processGO:00091541090.036
establishment of organelle localizationGO:00516561220.036
regulation of filopodium assemblyGO:0051489240.036
ribose phosphate metabolic processGO:00196931450.036
homeostatic processGO:00425921990.035
ovarian nurse cell to oocyte transportGO:0007300270.034
positive regulation of cell communicationGO:00106472500.034
organonitrogen compound catabolic processGO:19015651280.034
canonical wnt signaling pathwayGO:0060070210.033
eye photoreceptor cell developmentGO:0042462810.033
purine nucleoside metabolic processGO:00422781270.033
regulation of localizationGO:00328792750.033
regulation of cellular component movementGO:0051270420.033
compound eye morphogenesisGO:00017452490.033
proteolysisGO:00065081920.033
spermatid developmentGO:0007286980.033
regulation of protein kinase activityGO:0045859510.032
positive regulation of cell motilityGO:200014730.032
single organism catabolic processGO:00447122280.032
negative regulation of transcription dna templatedGO:00458922370.032
behavioral response to ethanolGO:0048149490.032
regulation of cell divisionGO:0051302720.031
actin cytoskeleton reorganizationGO:0031532220.031
organonitrogen compound metabolic processGO:19015643180.030
nucleobase containing compound catabolic processGO:00346551650.030
regulation of response to stressGO:00801342000.030
positive regulation of organelle organizationGO:0010638650.030
cellular nitrogen compound catabolic processGO:00442701650.029
gliogenesisGO:0042063800.029
negative regulation of cellular component organizationGO:00511291080.029
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.028
gland developmentGO:00487321910.028
positive regulation of actin filament polymerizationGO:0030838110.028
humoral immune responseGO:00069591170.028
positive regulation of intracellular signal transductionGO:19025331160.028
chemotaxisGO:00069352490.027
stem cell differentiationGO:00488631170.027
regulation of erbb signaling pathwayGO:1901184420.027
negative regulation of biosynthetic processGO:00098902770.027
cellular catabolic processGO:00442483720.027
cellular amine metabolic processGO:0044106120.027
purine ribonucleotide metabolic processGO:00091501450.027
response to growth factorGO:0070848310.027
kidney morphogenesisGO:006099330.027
regulation of protein modification processGO:00313991120.027
membrane protein ectodomain proteolysisGO:000650950.026
ribonucleotide catabolic processGO:00092611090.026
golgi vesicle transportGO:0048193270.026
actin filament bundle assemblyGO:0051017260.026
morphogenesis of an epitheliumGO:00020092760.026
genital disc developmentGO:0035215440.026
response to organic cyclic compoundGO:0014070890.026
response to lipidGO:0033993380.026
protein maturationGO:0051604710.026
actin filament based movementGO:0030048260.025
circulatory system developmentGO:0072359820.025
regulation of protein localizationGO:0032880760.025
phagocytosisGO:00069092150.025
response to bacteriumGO:00096171980.025
endosomal transportGO:0016197440.024
renal system developmentGO:0072001720.024
negative regulation of cytoskeleton organizationGO:0051494300.024
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.024
lamellipodium assemblyGO:0030032210.024
positive regulation of protein polymerizationGO:0032273140.024
immune effector processGO:0002252980.024
synaptic vesicle recyclingGO:0036465280.024
nucleoside metabolic processGO:00091161270.024
regulation of synaptic growth at neuromuscular junctionGO:0008582890.024
Fly
wound healingGO:0042060750.024
erbb signaling pathwayGO:0038127580.023
glycosyl compound metabolic processGO:19016571270.023
cytoplasmic transportGO:00164821300.023
positive regulation of biosynthetic processGO:00098913160.023
positive regulation of cytoskeleton organizationGO:0051495210.023
nucleoside catabolic processGO:00091641120.023
regulation of embryonic cell shapeGO:0016476300.023
regulation of transcription from rna polymerase ii promoterGO:00063573780.022
guanosine containing compound metabolic processGO:1901068740.022
regulation of anatomical structure sizeGO:00900661630.022
negative regulation of phosphatase activityGO:001092330.022
membrane organizationGO:00610241120.022
positive regulation of phosphate metabolic processGO:00459371390.022
positive regulation of developmental processGO:00510941430.022
Fly
carbohydrate derivative catabolic processGO:19011361180.022
regulation of cellular protein metabolic processGO:00322682430.022
regulation of synapse structure and activityGO:00508031280.022
Fly
negative regulation of phosphate metabolic processGO:0045936450.021
meiotic cell cycle processGO:19030461320.021
establishment of protein localizationGO:00451841630.021
tube formationGO:0035148210.021
positive regulation of rna metabolic processGO:00512542710.020
positive regulation of nucleic acid templated transcriptionGO:19035082660.020
cellular amino acid metabolic processGO:0006520610.020
positive regulation of phosphorus metabolic processGO:00105621390.020
cell cell junction organizationGO:0045216550.020
purine nucleotide metabolic processGO:00061631460.019
regulation of molecular functionGO:00650092170.019
hindgut developmentGO:0061525580.019
purine containing compound metabolic processGO:00725211550.019
positive regulation of endocytosisGO:0045807220.019
establishment of spindle localizationGO:0051293220.019
programmed cell deathGO:00125012570.019
hindgut morphogenesisGO:0007442580.019
catabolic processGO:00090564090.018
renal tubule developmentGO:0061326640.018
neuromuscular junction developmentGO:00075281490.018
Fly
regulation of ras protein signal transductionGO:0046578930.018
regulation of synapse organizationGO:00508071100.018
Fly
taxisGO:00423303040.018
positive regulation of cell proliferationGO:0008284470.018
mapk cascadeGO:00001651070.018
tissue morphogenesisGO:00487292970.018
regulation of cell morphogenesisGO:00226041630.018
regulation of protein phosphorylationGO:0001932640.018
axonogenesisGO:00074092900.018
response to oxygen containing compoundGO:19017002000.018
regulation of cellular localizationGO:00603411360.017
urogenital system developmentGO:0001655720.017
organophosphate catabolic processGO:00464341120.017
nuclear divisionGO:00002803320.017
protein modification processGO:00362114380.017
cellular metal ion homeostasisGO:0006875310.017
positive regulation of cellular biosynthetic processGO:00313283160.017
negative regulation of phosphorylationGO:0042326350.017
maintenance of locationGO:0051235730.017
negative regulation of organelle organizationGO:0010639560.017
striated muscle cell developmentGO:0055002500.017
multicellular organismal agingGO:00102591400.017
male gamete generationGO:00482322010.017
response to organic substanceGO:00100332840.017
cellular macromolecule localizationGO:00707272200.017
defense response to other organismGO:00985422250.017
negative regulation of nervous system developmentGO:0051961920.017
larval developmentGO:00021641040.017
positive regulation of cellular amino acid metabolic processGO:004576400.016
establishment of localization in cellGO:00516494020.016
establishment or maintenance of cytoskeleton polarityGO:0030952440.016
determination of imaginal disc primordiumGO:0007445110.016
morphogenesis of embryonic epitheliumGO:0016331940.016
muscle contractionGO:0006936130.016
gland morphogenesisGO:00226121450.016
open tracheal system developmentGO:00074242040.016
tube morphogenesisGO:00352391910.016
digestive tract developmentGO:00485651490.016
purine nucleotide catabolic processGO:00061951090.016
negative regulation of rna biosynthetic processGO:19026792400.016
establishment of tissue polarityGO:0007164870.016
regulation of synaptic transmissionGO:0050804690.015
protein transportGO:00150311550.015
ribonucleotide metabolic processGO:00092591450.015
positive regulation of phagocytosis engulfmentGO:006010010.015
protein localizationGO:00081042840.015
regulation of phosphatase activityGO:001092130.015
mrna processingGO:00063971040.015
regulation of transferase activityGO:0051338580.015
single organism membrane organizationGO:0044802930.015
stress activated mapk cascadeGO:0051403520.015
regulation of mapk cascadeGO:0043408920.015
rac protein signal transductionGO:001660130.015
synaptic transmissionGO:00072682880.015
Fly
ribonucleoside metabolic processGO:00091191270.015
citrate metabolic processGO:000610100.015
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.015
purine ribonucleoside metabolic processGO:00461281270.014
positive regulation of phagocytosisGO:005076630.014
tricarboxylic acid metabolic processGO:007235010.014
spindle organizationGO:00070512530.014
positive regulation of catalytic activityGO:00430851180.014
axon guidanceGO:00074112330.014
regulation of receptor mediated endocytosisGO:004825990.014
nucleoside monophosphate metabolic processGO:0009123520.014
regulation of phosphorylationGO:00423251470.014
appendage morphogenesisGO:00351073970.014
macromolecular complex assemblyGO:00650032560.014
delaminationGO:006023280.014
positive regulation of gene expressionGO:00106282900.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.014
rho protein signal transductionGO:0007266140.014
protein localization to plasma membraneGO:0072659130.014
lipid localizationGO:0010876540.014
response to molecule of fungal originGO:000223810.014
nephron developmentGO:007200630.014
erk1 and erk2 cascadeGO:0070371390.013
defense responseGO:00069523000.013
camera type eye developmentGO:004301040.013
ribonucleoside catabolic processGO:00424541120.013
cellular protein modification processGO:00064644380.013
appendage developmentGO:00487364010.013
jak stat cascadeGO:0007259490.013
atp metabolic processGO:0046034490.013
positive regulation of immune responseGO:0050778630.013
regulation of system processGO:0044057360.013
salivary gland morphogenesisGO:00074351450.013
digestive system developmentGO:00551231490.013
synapse organizationGO:00508081960.013
Fly
kidney developmentGO:000182230.013
protein localization to nucleusGO:0034504550.012
embryonic hindgut morphogenesisGO:0048619480.012
regulation of anatomical structure morphogenesisGO:00226032420.012
purine ribonucleoside triphosphate metabolic processGO:00092051190.012
cortical cytoskeleton organizationGO:0030865290.012
extracellular structure organizationGO:0043062460.012
actin nucleationGO:004501080.012
regulation of kinase activityGO:0043549530.012
positive regulation of nucleoside metabolic processGO:0045979470.012
nucleoside triphosphate catabolic processGO:00091431080.012
glycosyl compound catabolic processGO:19016581120.012
salivary gland developmentGO:00074311620.012
positive regulation of molecular functionGO:00440931360.012
intracellular protein transportGO:00068861040.012
signal transduction by phosphorylationGO:00230141070.012
pseudocleavageGO:003058890.012
regulation of cell adhesionGO:0030155270.012
gtp metabolic processGO:0046039720.012
initiation of dorsal closureGO:0007392120.011
protein importGO:0017038550.011
positive regulation of ras gtpase activityGO:0032320360.011
germline ring canal formationGO:0030725130.011
specification of symmetryGO:0009799130.011
single organism behaviorGO:00447083910.011
negative regulation of cellular protein metabolic processGO:0032269850.011
cellular homeostasisGO:0019725800.011
regulation of locomotionGO:0040012420.011
neuroblast proliferationGO:0007405740.011
apoptotic cell clearanceGO:0043277140.011
single organism carbohydrate metabolic processGO:0044723720.011
protein processingGO:0016485680.011
regulation of multicellular organismal developmentGO:20000264140.011
Fly
protein targetingGO:0006605640.011
blood circulationGO:0008015260.011
positive regulation of apoptotic processGO:0043065470.011
cognitionGO:00508901410.011
regulation of cell shapeGO:00083601130.011
wing disc morphogenesisGO:00074723440.011
regulation of cell developmentGO:00602842150.011
positive regulation of protein metabolic processGO:00512471280.011
regulation of nervous system developmentGO:00519602480.010
Fly
cell growthGO:00160491080.010
negative regulation of protein secretionGO:005070920.010
filopodium assemblyGO:0046847330.010
mitochondrial membrane organizationGO:000700630.010
regulation of cell differentiationGO:00455953020.010
wnt signaling pathwayGO:0016055980.010
protein phosphorylationGO:00064681690.010
response to hormoneGO:0009725450.010
monocarboxylic acid transportGO:001571830.010
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.010
cation transportGO:00068121100.010

Cortactin disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.171
nervous system diseaseDOID:86300.038
disease of cellular proliferationDOID:1456600.035
cancerDOID:16200.035
cardiovascular system diseaseDOID:128700.030
benign neoplasmDOID:006007200.021
organ system cancerDOID:005068600.016
muscle tissue diseaseDOID:6600.012
musculoskeletal system diseaseDOID:1700.012
muscular diseaseDOID:008000000.012
myopathyDOID:42300.012