Drosophila melanogaster

32 known processes

Pkg21D (Dmel_CG3324)

cGMP-dependent protein kinase 21D

(Aliases: cGMP,PKG 21D,Dmel\CG3324,PKG-21D,dg1,DG1,PKG,Pkg1,CG3324,Dg1)

Pkg21D biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
epithelial cell differentiationGO:00308553220.090
deathGO:00162652840.084
endocytosisGO:00068973100.079
organic substance transportGO:00717022570.078
single organism behaviorGO:00447083910.077
Fly
catabolic processGO:00090564090.075
Worm
vesicle mediated transportGO:00161923810.075
localization of cellGO:00516742570.070
organonitrogen compound metabolic processGO:19015643180.064
cellular protein modification processGO:00064644380.064
oxoacid metabolic processGO:00434361030.063
cellular catabolic processGO:00442483720.061
cell deathGO:00082192790.060
cellular response to chemical stimulusGO:00708871990.059
Worm
neuron projection guidanceGO:00974852410.058
taxisGO:00423303040.056
regulation of intracellular signal transductionGO:19025312360.055
cell migrationGO:00164772380.054
organic acid metabolic processGO:00060821030.054
columnar cuboidal epithelial cell developmentGO:00020662490.053
positive regulation of signal transductionGO:00099672230.053
epithelial cell migrationGO:00106311480.052
phagocytosisGO:00069092150.052
positive regulation of signalingGO:00230562430.051
adult behaviorGO:00305341370.050
columnar cuboidal epithelial cell differentiationGO:00020652560.049
carboxylic acid metabolic processGO:0019752920.048
organelle fissionGO:00482853400.048
intracellular signal transductionGO:00355563000.048
ameboidal type cell migrationGO:00016671510.048
chemotaxisGO:00069352490.048
lateral inhibitionGO:00463312060.047
positive regulation of nucleobase containing compound metabolic processGO:00459353320.046
ovarian follicle cell developmentGO:00307072480.046
regulation of programmed cell deathGO:00430671520.046
regulation of cell differentiationGO:00455953020.045
epithelial cell developmentGO:00020642740.044
developmental growthGO:00485892800.044
Worm
positive regulation of cell communicationGO:00106472500.044
positive regulation of response to stimulusGO:00485843230.044
programmed cell deathGO:00125012570.043
tissue morphogenesisGO:00487292970.042
response to oxygen containing compoundGO:19017002000.042
Worm Fly
regulation of cell deathGO:00109411730.042
morphogenesis of an epitheliumGO:00020092760.042
sterol homeostasisGO:005509240.041
lipid metabolic processGO:00066291210.041
response to abiotic stimulusGO:00096283410.041
axonogenesisGO:00074092900.040
nuclear divisionGO:00002803320.040
transcription from rna polymerase ii promoterGO:00063663680.039
protein modification processGO:00362114380.039
cell motilityGO:00488702510.039
regulation of anatomical structure sizeGO:00900661630.038
exocrine system developmentGO:00352721620.037
regulation of cellular amino acid metabolic processGO:000652100.037
regulation of cellular ketone metabolic processGO:001056530.037
imaginal disc derived wing morphogenesisGO:00074763370.037
appendage morphogenesisGO:00351073970.036
multi organism behaviorGO:00517051750.036
Worm
apoptotic processGO:00069151590.036
axon guidanceGO:00074112330.036
disaccharide transportGO:001576620.036
negative regulation of gene expressionGO:00106293870.036
forebrain developmentGO:003090020.036
wing disc morphogenesisGO:00074723440.035
gland morphogenesisGO:00226121450.035
nucleotide metabolic processGO:00091171610.035
proteolysisGO:00065081920.035
actin filament based processGO:00300292200.035
homeostatic processGO:00425921990.035
epithelium migrationGO:00901321480.035
macromolecular complex assemblyGO:00650032560.035
cellular amino acid metabolic processGO:0006520610.035
open tracheal system developmentGO:00074242040.034
regulation of anatomical structure morphogenesisGO:00226032420.034
single organism catabolic processGO:00447122280.034
small molecule metabolic processGO:00442813050.034
negative regulation of cellular metabolic processGO:00313243820.033
regulation of localizationGO:00328792750.033
cellular amine metabolic processGO:0044106120.033
meiosis iGO:0007127590.033
axon developmentGO:00615642970.033
response to organic substanceGO:00100332840.033
Worm Fly
appendage developmentGO:00487364010.032
regulation of multicellular organismal developmentGO:20000264140.032
post embryonic appendage morphogenesisGO:00351203850.032
positive regulation of nitrogen compound metabolic processGO:00511733540.032
regulation of organelle organizationGO:00330431960.032
salivary gland developmentGO:00074311620.031
respiratory system developmentGO:00605412130.030
regionalizationGO:00030024160.030
response to other organismGO:00517072930.030
oligosaccharide transportGO:001577220.030
organic substance catabolic processGO:19015753080.030
Worm
regulation of cellular component sizeGO:0032535980.029
protein localizationGO:00081042840.029
jak stat cascadeGO:0007259490.029
enzyme linked receptor protein signaling pathwayGO:00071671790.029
Worm
chromosome organizationGO:00512763600.029
meiotic cell cycleGO:00513211710.029
compound eye morphogenesisGO:00017452490.028
regulation of phosphorus metabolic processGO:00511742100.028
matingGO:00076181200.028
single organism biosynthetic processGO:00447112060.028
positive regulation of cell migrationGO:003033520.028
somatic muscle developmentGO:0007525660.027
body morphogenesisGO:001017120.027
purine nucleotide catabolic processGO:00061951090.027
defense responseGO:00069523000.027
imaginal disc derived appendage morphogenesisGO:00351143950.027
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.027
Worm
metal ion homeostasisGO:0055065440.027
organophosphate metabolic processGO:00196371950.027
sensory perceptionGO:00076001960.026
positive regulation of rna metabolic processGO:00512542710.026
imaginal disc derived appendage developmentGO:00487373990.026
chemical homeostasisGO:0048878920.026
salivary gland morphogenesisGO:00074351450.026
growthGO:00400073590.026
Worm
cellular ketone metabolic processGO:0042180240.026
actin filament organizationGO:00070151260.026
wnt signaling pathwayGO:0016055980.026
gland developmentGO:00487321910.026
response to external biotic stimulusGO:00432072930.026
developmental maturationGO:00217001720.025
positive regulation of cell motilityGO:200014730.025
regulation of catabolic processGO:00098941700.025
compound eye developmentGO:00487493070.025
regulation of transportGO:00510491810.025
cellular nitrogen compound catabolic processGO:00442701650.025
reproductive behaviorGO:00190981220.025
Worm
positive regulation of cellular biosynthetic processGO:00313283160.025
positive regulation of biosynthetic processGO:00098913160.025
connective tissue developmentGO:006144830.024
protein complex assemblyGO:00064612000.024
negative regulation of biosynthetic processGO:00098902770.024
regulation of catalytic activityGO:00507901850.024
establishment of localization in cellGO:00516494020.024
regulation of response to stressGO:00801342000.024
morphogenesis of a polarized epitheliumGO:0001738930.024
response to radiationGO:00093141550.023
response to organophosphorusGO:004668320.023
camera type eye developmentGO:004301040.023
cuticle developmentGO:0042335860.023
protein complex biogenesisGO:00702712010.023
kidney developmentGO:000182230.023
positive regulation of molecular functionGO:00440931360.022
telencephalon developmentGO:002153720.022
ion transportGO:00068111450.022
dna packagingGO:0006323910.022
purine ribonucleoside catabolic processGO:00461301120.022
cation transportGO:00068121100.022
locomotory behaviorGO:00076261760.022
Fly
positive regulation of macromolecule biosynthetic processGO:00105572830.022
establishment or maintenance of cell polarityGO:00071631670.022
regulation of cell sizeGO:0008361630.022
regulation of cellular component biogenesisGO:00440872010.021
small gtpase mediated signal transductionGO:0007264880.021
positive regulation of phosphorus metabolic processGO:00105621390.021
positive regulation of nucleic acid templated transcriptionGO:19035082660.021
tissue migrationGO:00901301550.021
neurological system processGO:00508773580.021
Fly
cellular component assembly involved in morphogenesisGO:00109271510.021
positive regulation of cellular amino acid metabolic processGO:004576400.021
multi organism reproductive behaviorGO:00447051210.021
Worm
regulation of developmental growthGO:00486381740.021
Worm
negative regulation of developmental processGO:00510932010.021
Worm
meiotic nuclear divisionGO:00071261510.021
ethanolamine containing compound metabolic processGO:004243940.021
positive regulation of intracellular signal transductionGO:19025331160.021
negative regulation of cellular component organizationGO:00511291080.020
cholesterol homeostasisGO:004263230.020
eye morphogenesisGO:00485922600.020
positive regulation of macromolecule metabolic processGO:00106044050.020
amine metabolic processGO:0009308120.020
purine ribonucleoside triphosphate metabolic processGO:00092051190.020
cellular response to endogenous stimulusGO:0071495800.020
Worm
intracellular transportGO:00469072280.020
protein phosphorylationGO:00064681690.020
cell cell signaling involved in cell fate commitmentGO:00451682100.020
positive regulation of transcription dna templatedGO:00458932660.020
chromatin organizationGO:00063252070.020
cell maturationGO:00484691440.020
cellular macromolecule localizationGO:00707272200.020
regulation of transcription from rna polymerase ii promoterGO:00063573780.020
border follicle cell migrationGO:00072981130.019
regulation of embryonic developmentGO:0045995680.019
regulation of synapse structure and activityGO:00508031280.019
positive regulation of multicellular organismal processGO:00512401430.019
regulation of apoptotic processGO:00429811300.019
single organism intracellular transportGO:19025822070.019
regulation of cell cycleGO:00517262910.019
mesodermal cell migrationGO:000807870.019
regulation of organ morphogenesisGO:2000027780.019
regulation of cellular amine metabolic processGO:003323830.019
regulation of behaviorGO:0050795750.019
Worm
digestive system developmentGO:00551231490.019
multi multicellular organism processGO:00447061230.019
Worm
chromatin modificationGO:00165681470.019
response to nitrogen compoundGO:1901698900.019
Worm
regulation of molecular functionGO:00650092170.019
cellular cation homeostasisGO:0030003380.019
tube developmentGO:00352952440.019
negative regulation of nucleobase containing compound metabolic processGO:00459342610.019
cellular modified amino acid metabolic processGO:0006575450.018
neuron recognitionGO:00080381010.018
eye developmentGO:00016543230.018
embryonic morphogenesisGO:00485982060.018
ras protein signal transductionGO:0007265880.018
response to organonitrogen compoundGO:0010243750.018
Worm
response to alcoholGO:0097305950.018
peptidyl amino acid modificationGO:00181931050.018
Worm
regulation of cell morphogenesisGO:00226041630.018
positive regulation of cellular amine metabolic processGO:003324000.018
response to endogenous stimulusGO:00097191190.018
Worm
organic cyclic compound catabolic processGO:19013611680.018
negative regulation of nitrogen compound metabolic processGO:00511722650.018
autophagyGO:00069141080.018
glycosyl compound metabolic processGO:19016571270.017
cellular lipid metabolic processGO:0044255830.017
dendrite morphogenesisGO:00488131990.017
response to bacteriumGO:00096171980.017
negative regulation of cellular biosynthetic processGO:00313272770.017
positive regulation of developmental processGO:00510941430.017
positive regulation of catalytic activityGO:00430851180.017
negative regulation of cell communicationGO:00106482230.017
tube morphogenesisGO:00352391910.017
male meiosisGO:0007140520.017
organic hydroxy compound metabolic processGO:1901615830.017
cellular macromolecular complex assemblyGO:00346221530.017
positive regulation of gene expressionGO:00106282900.017
response to biotic stimulusGO:00096072940.017
mesenchymal cell differentiationGO:004876210.017
anterior posterior pattern specificationGO:00099521360.017
nucleoside phosphate metabolic processGO:00067531620.017
nucleobase containing small molecule metabolic processGO:00550861740.017
axis specificationGO:00097981670.017
regulation of cell developmentGO:00602842150.017
cell fate specificationGO:0001708710.017
nucleoside phosphate catabolic processGO:19012921100.017
mating behaviorGO:00076171060.017
anion homeostasisGO:005508130.017
regulation of phosphate metabolic processGO:00192202100.017
cellular response to oxygen containing compoundGO:1901701790.017
Worm
ribonucleoside triphosphate metabolic processGO:00091991190.017
carbohydrate derivative metabolic processGO:19011352170.017
multicellular organismal reproductive behaviorGO:00330571100.017
Worm
negative regulation of signal transductionGO:00099682060.016
monocarboxylic acid transportGO:001571830.016
negative regulation of transcription dna templatedGO:00458922370.016
mesenchymal cell developmentGO:001403110.016
negative regulation of response to stimulusGO:00485852580.016
positive regulation of rna biosynthetic processGO:19026802660.016
establishment of tissue polarityGO:0007164870.016
nucleobase containing compound catabolic processGO:00346551650.016
cellular response to abiotic stimulusGO:0071214580.016
purine ribonucleoside metabolic processGO:00461281270.016
cognitionGO:00508901410.016
Fly
organophosphate catabolic processGO:00464341120.016
dna conformation changeGO:00711031050.016
ovarian follicle cell migrationGO:00072971210.016
regulation of cellular localizationGO:00603411360.016
organelle assemblyGO:00709251980.016
ribose phosphate metabolic processGO:00196931450.016
purine nucleoside triphosphate metabolic processGO:00091441190.016
cation homeostasisGO:0055080510.016
heterocycle catabolic processGO:00467001660.016
purine nucleoside metabolic processGO:00422781270.016
negative regulation of cell deathGO:0060548810.016
regulation of mitotic cell cycleGO:00073461900.016
nucleoside triphosphate metabolic processGO:00091411200.016
embryonic development via the syncytial blastodermGO:00017001480.016
establishment of planar polarityGO:0001736870.016
purine containing compound catabolic processGO:00725231120.015
response to salt stressGO:0009651110.015
organonitrogen compound catabolic processGO:19015651280.015
muscle structure developmentGO:00610612240.015
negative regulation of nucleic acid templated transcriptionGO:19035072400.015
instar larval developmentGO:0002168550.015
chromosome segregationGO:00070591570.015
actin cytoskeleton organizationGO:00300362060.015
digestive tract developmentGO:00485651490.015
cell fate determinationGO:0001709910.015
spermatogenesisGO:00072832000.015
ribonucleotide catabolic processGO:00092611090.015
regulation of protein metabolic processGO:00512462560.015
dna metabolic processGO:00062592270.015
nitrogen compound transportGO:0071705850.015
motor neuron axon guidanceGO:0008045580.015
aromatic compound catabolic processGO:00194391660.015
retina development in camera type eyeGO:006004140.015
response to lipopolysaccharideGO:003249640.015
negative regulation of developmental growthGO:0048640640.015
Worm
response to woundingGO:0009611940.015
cellular response to organic substanceGO:00713101320.015
Worm
larval developmentGO:00021641040.015
embryonic pattern specificationGO:00098801740.015
regulation of cellular protein metabolic processGO:00322682430.015
embryonic axis specificationGO:00005781070.015
purine containing compound metabolic processGO:00725211550.015
maintenance of locationGO:0051235730.015
defense response to bacteriumGO:00427421780.014
purine nucleoside catabolic processGO:00061521120.014
metal ion transportGO:0030001740.014
muscle cell differentiationGO:00426921030.014
negative regulation of signalingGO:00230572190.014
rhythmic processGO:00485111060.014
signal transduction by phosphorylationGO:00230141070.014
cell recognitionGO:00080371020.014
protein transportGO:00150311550.014
ion homeostasisGO:0050801550.014
response to nutrient levelsGO:00316671140.014
Fly
nucleotide catabolic processGO:00091661090.014
response to monosaccharideGO:003428440.014
regulation of cell proliferationGO:00421271630.014
positive regulation of cell differentiationGO:0045597640.014
carbohydrate derivative catabolic processGO:19011361180.014
embryo development ending in birth or egg hatchingGO:00097921520.014
eggshell formationGO:00307031050.014
phosphorylationGO:00163102940.014
positive regulation of lipid storageGO:001088440.014
purine ribonucleotide catabolic processGO:00091541090.014
male gamete generationGO:00482322010.014
developmental growth involved in morphogenesisGO:0060560650.014
regulation of i kappab kinase nf kappab signalingGO:004312220.014
regulation of locomotionGO:0040012420.014
establishment of protein localizationGO:00451841630.014
limb developmentGO:006017310.014
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.014
anatomical structure homeostasisGO:0060249970.014
sensory organ morphogenesisGO:00905962600.014
regulation of growthGO:00400082330.014
Worm
regulation of purine nucleotide metabolic processGO:1900542620.014
nucleoside triphosphate catabolic processGO:00091431080.014
regulation of epithelial cell proliferationGO:005067840.013
ribonucleoside triphosphate catabolic processGO:00092031080.013
negative regulation of cellular protein metabolic processGO:0032269850.013
limb morphogenesisGO:003510810.013
guanosine containing compound metabolic processGO:1901068740.013
regulation of cytoskeleton organizationGO:0051493890.013
lipid biosynthetic processGO:0008610460.013
cytoplasmic transportGO:00164821300.013
organonitrogen compound biosynthetic processGO:19015661170.013
regulation of mapk cascadeGO:0043408920.013
ribonucleotide metabolic processGO:00092591450.013
synaptic transmissionGO:00072682880.013
nucleoside catabolic processGO:00091641120.013
ribonucleoside catabolic processGO:00424541120.013
lipid homeostasisGO:0055088330.013
chromatin silencingGO:0006342760.013
purine nucleotide metabolic processGO:00061631460.013
purine nucleoside triphosphate catabolic processGO:00091461080.013
organ growthGO:0035265560.013
Worm
non sensory hair organizationGO:0035316470.013
positive regulation of cell deathGO:0010942690.013
mapk cascadeGO:00001651070.013
negative regulation of rna metabolic processGO:00512532510.013
digestive tract morphogenesisGO:00485461270.012
cholesterol transportGO:003030120.012
cellular response to carbohydrate stimulusGO:007132240.012
cellular response to hormone stimulusGO:0032870440.012
Worm
regulation of cell cycle processGO:00105641810.012
secondary metabolic processGO:0019748750.012
response to organic cyclic compoundGO:0014070890.012
cellular response to lipopolysaccharideGO:007122230.012
agingGO:00075681430.012
Worm
immune response activating signal transductionGO:000275720.012
hindbrain developmentGO:003090220.012
negative regulation of multicellular organismal processGO:00512411420.012
Worm
endodermal cell differentiationGO:003598730.012
spindle organizationGO:00070512530.012
response to extracellular stimulusGO:00099911160.012
Fly
meiotic cell cycle processGO:19030461320.012
regulation of neurogenesisGO:00507671580.012
negative regulation of cell cycleGO:00457861160.012
regulation of gene expression epigeneticGO:00400291280.012
purine ribonucleotide metabolic processGO:00091501450.012
alditol phosphate metabolic processGO:005264620.012
dendrite developmentGO:00163582040.012
gene silencingGO:00164581380.012
outflow tract morphogenesisGO:000315140.012
regulation of autophagyGO:0010506620.012
mitotic nuclear divisionGO:00070672130.012
cellular response to biotic stimulusGO:007121640.012
regulation of response to woundingGO:1903034190.012
peptidyl proline hydroxylationGO:001951110.012
regulation of small gtpase mediated signal transductionGO:0051056930.012
positive regulation of catabolic processGO:00098961050.012
negative regulation of protein metabolic processGO:0051248850.012
regulation of ras protein signal transductionGO:0046578930.012
vitamin metabolic processGO:000676620.012
cellular protein localizationGO:00346131600.012
negative regulation of growthGO:0045926840.012
Worm
regulation of cell projection organizationGO:0031344920.012
histolysisGO:00075591020.012
single organism cellular localizationGO:19025801800.012
negative regulation of cell differentiationGO:00455961430.012
anterior posterior axis specification embryoGO:00085951030.012
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.012
mitotic cell cycle phase transitionGO:00447721380.012
cellular response to dna damage stimulusGO:00069742230.011
response to ionizing radiationGO:0010212320.011
chromatin assembly or disassemblyGO:0006333520.011
positive regulation of cellular component biogenesisGO:0044089800.011
cell projection assemblyGO:0030031940.011
membrane organizationGO:00610241120.011
skin developmentGO:0043588650.011
tripartite regional subdivisionGO:00073511030.011
regulation of hydrolase activityGO:0051336970.011
regulation of proteolysisGO:0030162870.011
small molecule biosynthetic processGO:0044283370.011
epibolyGO:009050420.011
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
regulation of hormone levelsGO:0010817400.011
learning or memoryGO:00076111410.011
Fly
cellular protein complex assemblyGO:0043623710.011
developmental programmed cell deathGO:00106231380.011
anterior posterior axis specificationGO:00099481090.011
chorion containing eggshell formationGO:00073041050.011
positive regulation of hydrolase activityGO:0051345780.011
androgen metabolic processGO:000820910.011
stem cell developmentGO:0048864790.011
negative regulation of rna biosynthetic processGO:19026792400.011
cellular response to nitrogen compoundGO:1901699510.011
Worm
camera type eye morphogenesisGO:004859320.011
regulation of epithelial cell differentiationGO:003085640.011
response to glucoseGO:000974920.011
regulation of neuron differentiationGO:00456641030.011
extrinsic apoptotic signaling pathwayGO:009719110.011
cytokinesisGO:0000910900.011
golgi organizationGO:0007030660.011
histone modificationGO:00165701060.011
regulation of cellular catabolic processGO:00313291570.011
cell proliferationGO:00082832990.011
cytoplasm organizationGO:0007028640.011
synapse organizationGO:00508081960.011
acetylcholine metabolic processGO:000829120.011
regulation of multi organism processGO:00439001310.011
Worm
cellular homeostasisGO:0019725800.011
response to light stimulusGO:00094161240.011
covalent chromatin modificationGO:00165691060.011
response to osmotic stressGO:0006970140.011
negative regulation of macromolecule biosynthetic processGO:00105582700.011
gastrulationGO:0007369700.011
macromolecule catabolic processGO:00090571610.011
Worm
detection of chemical stimulusGO:0009593930.011
detection of abiotic stimulusGO:0009582660.011
endomembrane system organizationGO:00102561190.011
dna methylationGO:000630640.011
regulation of sterol transportGO:003237110.010
feeding behaviorGO:0007631500.010
Fly
regulation of cellular component movementGO:0051270420.010
endoderm formationGO:000170630.010
negative regulation of organelle organizationGO:0010639560.010
oxidation reduction processGO:00551141230.010
positive regulation of transportGO:0051050920.010
sex differentiationGO:0007548810.010
response to inorganic substanceGO:0010035440.010
embryonic organ developmentGO:0048568500.010
regulation of sequestering of triglycerideGO:001088930.010
regulation of lipid transportGO:003236830.010
nucleoside metabolic processGO:00091161270.010
ribonucleoside metabolic processGO:00091191270.010
regulation of steroid metabolic processGO:001921820.010
regulation of cellular response to stressGO:0080135890.010
response to oxygen levelsGO:0070482590.010
posttranscriptional regulation of gene expressionGO:00106081450.010
wound healingGO:0042060750.010
sensory perception of painGO:001923340.010
choline metabolic processGO:001969510.010
cellular response to monosaccharide stimulusGO:007132620.010

Pkg21D disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.066
disease of metabolismDOID:001466700.018
nervous system diseaseDOID:86300.017
urinary system diseaseDOID:1800.015
inherited metabolic disorderDOID:65500.013
sensory system diseaseDOID:005015500.012
carbohydrate metabolism diseaseDOID:005001300.011
glucose metabolism diseaseDOID:419400.011
diabetes mellitusDOID:935100.011
acquired metabolic diseaseDOID:006015800.011
type 2 diabetes mellitusDOID:935200.011
cardiovascular system diseaseDOID:128700.011