IMP: Integrative Multi-species Prediction

Drosophila melanogaster

58 known processes

spn-B (Dmel_CG3325)

spindle B

(Aliases: Dmel\CG3325,rad51-like,Rad51,spnB,SpnB,XRCC3,CG3325)

FLYBASE: FBgn0003480
Entrez: 41746
UniProtKB: O77135

Process Predictions
Disease Predictions

spn-B biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
reciprocal meiotic recombination	GO:0007131	19	1.000
germarium derived oocyte differentiation	GO:0030706	29	0.999
germarium derived egg chamber formation	GO:0007293	101	0.999
chorion containing eggshell formation	GO:0007304	105	0.998
karyosome formation	GO:0030717	22	0.993
polarity specification of dorsal ventral axis	GO:0009951	6	0.991
germarium derived oocyte fate determination	GO:0007294	26	0.991
reciprocal dna recombination	GO:0035825	19	0.990
dna recombination	GO:0006310	32	0.990	Human
recombinational repair	GO:0000725	13	0.985	Human
eggshell chorion assembly	GO:0007306	66	0.979
meiosis i	GO:0007127	59	0.974
dorsal appendage formation	GO:0046843	47	0.965
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.960
eggshell formation	GO:0030703	105	0.957
polarity specification of anterior posterior axis	GO:0009949	5	0.955
meiotic chromosome segregation	GO:0045132	59	0.955
organelle fission	GO:0048285	340	0.955
ovarian follicle cell development	GO:0030707	248	0.950
meiotic cell cycle	GO:0051321	171	0.944
meiotic cell cycle process	GO:1903046	132	0.939
meiotic nuclear division	GO:0007126	151	0.935
double strand break repair via homologous recombination	GO:0000724	13	0.919	Human
oocyte differentiation	GO:0009994	145	0.901
dna metabolic process	GO:0006259	227	0.890	Human
chromosome organization	GO:0051276	360	0.889
dna damage checkpoint	GO:0000077	78	0.877
columnar cuboidal epithelial cell development	GO:0002066	249	0.876
cellular response to dna damage stimulus	GO:0006974	223	0.818	Human
dorsal ventral axis specification	GO:0009950	66	0.816
cell cycle checkpoint	GO:0000075	95	0.809	Human
chromosome segregation	GO:0007059	157	0.808
dorsal ventral pattern formation	GO:0009953	133	0.765
specification of axis polarity	GO:0065001	6	0.728
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.728	Human
dna geometric change	GO:0032392	16	0.722
dna integrity checkpoint	GO:0031570	81	0.718
double strand break repair via synthesis dependent strand annealing	GO:0045003	6	0.710
g2 dna damage checkpoint	GO:0031572	69	0.709
resolution of meiotic recombination intermediates	GO:0000712	6	0.691
axis specification	GO:0009798	167	0.678
nuclear division	GO:0000280	332	0.674
mitotic cell cycle phase transition	GO:0044772	138	0.665
epithelial cell development	GO:0002064	274	0.657
oocyte fate determination	GO:0030716	27	0.649
double strand break repair	GO:0006302	26	0.635	Human
regulation of cell cycle process	GO:0010564	181	0.620	Human
regulation of cell cycle phase transition	GO:1901987	130	0.619	Human
regulation of mitotic cell cycle	GO:0007346	190	0.604	Human
nucleotide excision repair	GO:0006289	8	0.582
oocyte localization involved in germarium derived egg chamber formation	GO:0030720	12	0.525
mitotic dna damage checkpoint	GO:0044773	74	0.505
oocyte nucleus localization involved in oocyte dorsal ventral axis specification	GO:0051663	12	0.502
dna repair	GO:0006281	54	0.493	Human
cellular component assembly involved in morphogenesis	GO:0010927	151	0.475
oocyte dorsal ventral axis specification	GO:0007310	34	0.466
aromatic compound catabolic process	GO:0019439	166	0.462	Human
positive regulation of mitotic cell cycle phase transition	GO:1901992	20	0.455
female meiosis chromosome segregation	GO:0016321	33	0.452
microtubule organizing center organization	GO:0031023	168	0.426	Human
negative regulation of cell cycle phase transition	GO:1901988	103	0.390	Human
cell cycle phase transition	GO:0044770	140	0.386
double strand break repair via nonhomologous end joining	GO:0006303	5	0.380
female meiotic division	GO:0007143	70	0.374
regionalization	GO:0003002	416	0.358
heterocycle catabolic process	GO:0046700	166	0.357	Human
oocyte development	GO:0048599	124	0.330
dna duplex unwinding	GO:0032508	16	0.328
oocyte axis specification	GO:0007309	108	0.328
anterior posterior pattern specification	GO:0009952	136	0.326
organic cyclic compound catabolic process	GO:1901361	168	0.315	Human
regulation of cell cycle	GO:0051726	291	0.315	Human
dna synthesis involved in dna repair	GO:0000731	5	0.308
nucleobase containing compound catabolic process	GO:0034655	165	0.303	Human
male gamete generation	GO:0048232	201	0.302
anterior posterior axis specification	GO:0009948	109	0.287
spermatogenesis	GO:0007283	200	0.285
oocyte anterior posterior axis specification	GO:0007314	72	0.283
cell fate determination	GO:0001709	91	0.282
sister chromatid segregation	GO:0000819	92	0.273
non recombinational repair	GO:0000726	7	0.273
organic substance catabolic process	GO:1901575	308	0.262	Human
mitotic dna integrity checkpoint	GO:0044774	75	0.260
cellular catabolic process	GO:0044248	372	0.253	Human
cellular nitrogen compound catabolic process	GO:0044270	165	0.243	Human
response to abiotic stimulus	GO:0009628	341	0.241
actin cytoskeleton organization	GO:0030036	206	0.221
male meiosis	GO:0007140	52	0.219
chromosome separation	GO:0051304	42	0.218
negative regulation of cell cycle	GO:0045786	116	0.207	Human
cellular macromolecule catabolic process	GO:0044265	136	0.201	Human
gene silencing	GO:0016458	138	0.197
telomere maintenance via recombination	GO:0000722	1	0.191
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.187
macromolecule catabolic process	GO:0009057	161	0.182	Human
mitotic g2 m transition checkpoint	GO:0044818	70	0.177
epithelial cell differentiation	GO:0030855	322	0.169
positive regulation of mitotic cell cycle	GO:0045931	34	0.169	Human
oocyte construction	GO:0007308	112	0.165
cellular macromolecule localization	GO:0070727	220	0.154
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.151
mitotic g2 dna damage checkpoint	GO:0007095	69	0.150
cell division	GO:0051301	248	0.149
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.142
g2 m transition of mitotic cell cycle	GO:0000086	19	0.132
dna catabolic process	GO:0006308	16	0.132	Human
small molecule metabolic process	GO:0044281	305	0.128
rna localization	GO:0006403	115	0.127
transcription from rna polymerase ii promoter	GO:0006366	368	0.127
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.124	Human
response to organic substance	GO:0010033	284	0.112
response to organonitrogen compound	GO:0010243	75	0.109
intracellular mrna localization	GO:0008298	66	0.105
dorsal ventral axis specification ovarian follicular epithelium	GO:0008069	13	0.100
regulation of gene expression epigenetic	GO:0040029	128	0.100
regulation of dna metabolic process	GO:0051052	34	0.098
regulation of protein metabolic process	GO:0051246	256	0.093	Human
mitotic cell cycle checkpoint	GO:0007093	88	0.088	Human
mitotic sister chromatid segregation	GO:0000070	87	0.087
positive regulation of dna endoreduplication	GO:0032877	4	0.084
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.082
apoptotic process	GO:0006915	159	0.082
spindle organization	GO:0007051	253	0.082
mitotic recombination	GO:0006312	2	0.080	Human
negative regulation of oskar mrna translation	GO:0007319	5	0.079
positive regulation of cell cycle process	GO:0090068	28	0.077	Human
negative regulation of transposition	GO:0010529	12	0.076
positive regulation of cellular biosynthetic process	GO:0031328	316	0.075
negative regulation of mitotic cell cycle	GO:0045930	109	0.074	Human
pole plasm assembly	GO:0007315	61	0.073
negative regulation of signal transduction	GO:0009968	206	0.071
cell cycle dna replication	GO:0044786	23	0.070
response to light stimulus	GO:0009416	124	0.069
negative regulation of cell cycle process	GO:0010948	109	0.069	Human
catabolic process	GO:0009056	409	0.066	Human
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.066
gene silencing by rna	GO:0031047	57	0.065
negative regulation of cellular component organization	GO:0051129	108	0.064	Human
ras protein signal transduction	GO:0007265	88	0.064
ovarian fusome organization	GO:0030723	11	0.063
meiotic chromosome separation	GO:0051307	8	0.062
response to caffeine	GO:0031000	12	0.062
embryonic pattern specification	GO:0009880	174	0.061
eggshell chorion gene amplification	GO:0007307	9	0.060
positive regulation of macromolecule metabolic process	GO:0010604	405	0.060
positive regulation of cell cycle	GO:0045787	43	0.060	Human
ribose phosphate metabolic process	GO:0019693	145	0.059
nucleobase containing small molecule metabolic process	GO:0055086	174	0.059
cell maturation	GO:0048469	144	0.058
chorion containing eggshell pattern formation	GO:0030381	11	0.058
pirna metabolic process	GO:0034587	10	0.055
ncrna 3 end processing	GO:0043628	17	0.055
death	GO:0016265	284	0.053
cytoplasmic transport nurse cell to oocyte	GO:0007303	12	0.053
regulation of response to stress	GO:0080134	200	0.052
mitotic nuclear division	GO:0007067	213	0.052
cell cycle g2 m phase transition	GO:0044839	22	0.052
nucleoside triphosphate catabolic process	GO:0009143	108	0.050
negative regulation of rna metabolic process	GO:0051253	251	0.049
positive regulation of biosynthetic process	GO:0009891	316	0.049
organonitrogen compound metabolic process	GO:1901564	318	0.049
response to radiation	GO:0009314	155	0.048
dna conformation change	GO:0071103	105	0.048
phosphorylation	GO:0016310	294	0.047
actin filament based process	GO:0030029	220	0.047
purine ribonucleoside catabolic process	GO:0046130	112	0.047
actin filament organization	GO:0007015	126	0.046
sister chromatid cohesion	GO:0007062	18	0.045
negative regulation of rna biosynthetic process	GO:1902679	240	0.045
programmed cell death	GO:0012501	257	0.044
ribonucleoside catabolic process	GO:0042454	112	0.043
purine ribonucleoside metabolic process	GO:0046128	127	0.043
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.042
ribonucleoside metabolic process	GO:0009119	127	0.042
regulation of pole plasm oskar mrna localization	GO:0007317	27	0.040
negative regulation of cellular metabolic process	GO:0031324	382	0.040	Human
nucleoside phosphate catabolic process	GO:1901292	110	0.039
body morphogenesis	GO:0010171	2	0.037
regulation of catabolic process	GO:0009894	170	0.037	Human
regulation of phosphorus metabolic process	GO:0051174	210	0.036
developmental maturation	GO:0021700	172	0.035
single organism biosynthetic process	GO:0044711	206	0.035
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.035
signal transduction by phosphorylation	GO:0023014	107	0.034
single organism cellular localization	GO:1902580	180	0.034
blastoderm segmentation	GO:0007350	159	0.033
dna double strand break processing	GO:0000729	3	0.033
oocyte maturation	GO:0001556	3	0.033
endocytosis	GO:0006897	310	0.032
nucleoside metabolic process	GO:0009116	127	0.032
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.032
targeting of mrna for destruction involved in rna interference	GO:0030423	4	0.031
positive regulation of cellular component organization	GO:0051130	156	0.031
purine containing compound catabolic process	GO:0072523	112	0.031
response to organic cyclic compound	GO:0014070	89	0.031
mrna processing	GO:0006397	104	0.031
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.031
purine containing compound metabolic process	GO:0072521	155	0.031
meiotic sister chromatid segregation	GO:0045144	6	0.030
cellular macromolecular complex assembly	GO:0034622	153	0.030
rna polymerase ii transcriptional preinitiation complex assembly	GO:0051123	20	0.030
chromatin organization	GO:0006325	207	0.029
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.029
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.028
organelle assembly	GO:0070925	198	0.028
chromatin modification	GO:0016568	147	0.028
positive regulation of signal transduction	GO:0009967	223	0.027
positive regulation of signaling	GO:0023056	243	0.027
dna amplification	GO:0006277	11	0.027
carbohydrate derivative metabolic process	GO:1901135	217	0.027
negative regulation of cellular biosynthetic process	GO:0031327	277	0.026
small gtpase mediated signal transduction	GO:0007264	88	0.026
protein modification process	GO:0036211	438	0.026
single organism catabolic process	GO:0044712	228	0.026
vesicle mediated transport	GO:0016192	381	0.026
posttranscriptional gene silencing	GO:0016441	46	0.026
nucleus localization	GO:0051647	34	0.026
positive regulation of catabolic process	GO:0009896	105	0.026
nucleoside phosphate metabolic process	GO:0006753	162	0.025
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.025
cell death	GO:0008219	279	0.025
response to camptothecin	GO:1901563	2	0.025
chromatin remodeling	GO:0006338	72	0.025
cytoplasm organization	GO:0007028	64	0.025
organophosphate metabolic process	GO:0019637	195	0.025
response to alkaloid	GO:0043279	26	0.025
oocyte microtubule cytoskeleton organization	GO:0016325	35	0.024
negative regulation of cell communication	GO:0010648	223	0.024
protein phosphorylation	GO:0006468	169	0.024
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification	GO:0030722	6	0.024
response to nitrogen compound	GO:1901698	90	0.024
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.024
purine nucleoside monophosphate catabolic process	GO:0009128	38	0.023
nuclear dna replication	GO:0033260	1	0.023
purine nucleoside metabolic process	GO:0042278	127	0.023
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.023
medium chain fatty acid metabolic process	GO:0051791	1	0.023
regulation of meiosis	GO:0040020	3	0.023
protein dna complex subunit organization	GO:0071824	86	0.022
regulation of organelle organization	GO:0033043	196	0.022	Human
positive regulation of response to stimulus	GO:0048584	323	0.022
positive regulation of nuclear transcribed mrna poly a tail shortening	GO:0060213	4	0.022
negative regulation of erk1 and erk2 cascade	GO:0070373	3	0.022
response to ionizing radiation	GO:0010212	32	0.022
regulation of nuclear division	GO:0051783	58	0.022	Human
purine nucleotide metabolic process	GO:0006163	146	0.021
regulation of cytoskeleton organization	GO:0051493	89	0.021	Human
negative regulation of meiotic cell cycle	GO:0051447	2	0.021
positive regulation of hydrolase activity	GO:0051345	78	0.021
sex differentiation	GO:0007548	81	0.021
regulation of multicellular organismal development	GO:2000026	414	0.021
cellular response to radiation	GO:0071478	52	0.021
positive regulation of intracellular signal transduction	GO:1902533	116	0.021
protein dna complex assembly	GO:0065004	63	0.021
positive regulation of phosphate metabolic process	GO:0045937	139	0.020
positive regulation of cellular catabolic process	GO:0031331	95	0.020
cellular response to organic substance	GO:0071310	132	0.020
positive regulation of gene expression	GO:0010628	290	0.020
anion homeostasis	GO:0055081	3	0.020
chaeta morphogenesis	GO:0008407	42	0.019
compound eye photoreceptor cell differentiation	GO:0001751	140	0.019
positive regulation of mapk cascade	GO:0043410	63	0.019
nucleoside catabolic process	GO:0009164	112	0.019
protein complex assembly	GO:0006461	200	0.019
glycosyl compound catabolic process	GO:1901658	112	0.019
nucleotide metabolic process	GO:0009117	161	0.019
regulation of programmed cell death	GO:0043067	152	0.019
regulation of g2 m transition of mitotic cell cycle	GO:0010389	15	0.019
nucleoside triphosphate metabolic process	GO:0009141	120	0.018
peptidyl amino acid modification	GO:0018193	105	0.018
embryo development ending in birth or egg hatching	GO:0009792	152	0.018
embryonic axis specification	GO:0000578	107	0.018
regulation of double strand break repair	GO:2000779	3	0.018
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.018
positive regulation of phosphorus metabolic process	GO:0010562	139	0.018
ribonucleotide catabolic process	GO:0009261	109	0.018
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.018
response to endogenous stimulus	GO:0009719	119	0.018
posttranscriptional gene silencing by rna	GO:0035194	45	0.017
phagocytosis	GO:0006909	215	0.017
regulation of mapk cascade	GO:0043408	92	0.017
response to oxygen containing compound	GO:1901700	200	0.017
purine nucleoside catabolic process	GO:0006152	112	0.017
positive regulation of cell cycle phase transition	GO:1901989	20	0.017
erbb signaling pathway	GO:0038127	58	0.017
glycosyl compound metabolic process	GO:1901657	127	0.017
regulation of erk1 and erk2 cascade	GO:0070372	39	0.017
chromosome organization involved in meiosis	GO:0070192	10	0.017
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.017
ion transport	GO:0006811	145	0.017
dna alkylation	GO:0006305	4	0.017
negative regulation of protein metabolic process	GO:0051248	85	0.017	Human
immune response	GO:0006955	246	0.016
organonitrogen compound catabolic process	GO:1901565	128	0.016
morphogenesis of follicular epithelium	GO:0016333	36	0.016
chromosome condensation	GO:0030261	41	0.016
positive regulation of mrna catabolic process	GO:0061014	5	0.016
pole plasm rna localization	GO:0007316	52	0.016
negative regulation of gene expression	GO:0010629	387	0.016	Human
polyol biosynthetic process	GO:0046173	3	0.016
regulation of cellular response to stress	GO:0080135	89	0.016
regulation of cellular localization	GO:0060341	136	0.016
intracellular signal transduction	GO:0035556	300	0.016
response to decreased oxygen levels	GO:0036293	58	0.016
carbohydrate derivative catabolic process	GO:1901136	118	0.016
organophosphate catabolic process	GO:0046434	112	0.016
positive regulation of dna metabolic process	GO:0051054	12	0.016
regulation of ras protein signal transduction	GO:0046578	93	0.016
rna processing	GO:0006396	147	0.016
regulation of phosphate metabolic process	GO:0019220	210	0.015
rna interference	GO:0016246	27	0.015
segmentation	GO:0035282	207	0.015
macromolecular complex assembly	GO:0065003	256	0.015
regulation of mrna metabolic process	GO:1903311	72	0.015
male pronucleus assembly	GO:0035039	6	0.015
cell cycle arrest	GO:0007050	4	0.015
purine ribonucleotide metabolic process	GO:0009150	145	0.015
negative regulation of organelle organization	GO:0010639	56	0.015	Human
aging	GO:0007568	143	0.015
determination of adult lifespan	GO:0008340	137	0.015
purine ribonucleotide catabolic process	GO:0009154	109	0.014
establishment or maintenance of cell polarity	GO:0007163	167	0.014
dna biosynthetic process	GO:0071897	24	0.014
spermatid development	GO:0007286	98	0.014
regulation of cellular protein metabolic process	GO:0032268	243	0.014	Human
tissue morphogenesis	GO:0048729	297	0.014
anatomical structure homeostasis	GO:0060249	97	0.014
cell motility	GO:0048870	251	0.014
negative regulation of signaling	GO:0023057	219	0.014
regulation of catalytic activity	GO:0050790	185	0.014
positive regulation of molecular function	GO:0044093	136	0.014
cellular protein modification process	GO:0006464	438	0.014
regulation of response to dna damage stimulus	GO:2001020	23	0.014
ribonucleotide metabolic process	GO:0009259	145	0.013
nucleoside monophosphate metabolic process	GO:0009123	52	0.013
histone acetylation	GO:0016573	38	0.013
carboxylic acid metabolic process	GO:0019752	92	0.013
negative regulation of transcription dna templated	GO:0045892	237	0.013
translesion synthesis	GO:0019985	2	0.013
positive regulation of protein metabolic process	GO:0051247	128	0.013
nucleotide catabolic process	GO:0009166	109	0.013
positive regulation of catalytic activity	GO:0043085	118	0.013
positive regulation of phosphorylation	GO:0042327	87	0.013
negative regulation of biosynthetic process	GO:0009890	277	0.013
appendage morphogenesis	GO:0035107	397	0.013
cell aging	GO:0007569	2	0.013
establishment of protein localization	GO:0045184	163	0.013
mrna metabolic process	GO:0016071	124	0.013
regulation of apoptotic process	GO:0042981	130	0.013
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.012
cell proliferation	GO:0008283	299	0.012
negative regulation of growth	GO:0045926	84	0.012
mapk cascade	GO:0000165	107	0.012
regulation of phosphorylation	GO:0042325	147	0.012
anterior posterior axis specification embryo	GO:0008595	103	0.012
regulation of cellular catabolic process	GO:0031329	157	0.012	Human
reproductive system development	GO:0061458	74	0.012
negative regulation of intracellular signal transduction	GO:1902532	57	0.012
locomotory behavior	GO:0007626	176	0.012
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.012
protein complex biogenesis	GO:0070271	201	0.012
dna replication	GO:0006260	48	0.012
male meiosis i	GO:0007141	9	0.012
response to organophosphorus	GO:0046683	2	0.012
response to oxygen levels	GO:0070482	59	0.012
secondary metabolite catabolic process	GO:0090487	1	0.012
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.012
dna dependent dna replication	GO:0006261	17	0.012
imaginal disc derived appendage development	GO:0048737	399	0.011
developmental growth	GO:0048589	280	0.011
dna templated transcriptional preinitiation complex assembly	GO:0070897	20	0.011
postreplication repair	GO:0006301	2	0.011
negative regulation of cellular protein metabolic process	GO:0032269	85	0.011	Human
establishment or maintenance of polarity of follicular epithelium	GO:0016334	26	0.011
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay	GO:1900153	4	0.011
growth	GO:0040007	359	0.011
purine ribonucleoside monophosphate catabolic process	GO:0009169	38	0.011
striated muscle cell differentiation	GO:0051146	90	0.011
meiotic sister chromatid cohesion	GO:0051177	6	0.011
positive regulation of developmental process	GO:0051094	143	0.011
positive regulation of g2 m transition of mitotic cell cycle	GO:0010971	2	0.011
neurological system process	GO:0050877	358	0.011
signal transduction in response to dna damage	GO:0042770	3	0.011
regulation of mrna processing	GO:0050684	71	0.011
positive regulation of cell development	GO:0010720	61	0.011
positive regulation of cell communication	GO:0010647	250	0.011
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.011
telomere maintenance	GO:0000723	21	0.011
response to uv	GO:0009411	24	0.011
immune response regulating signaling pathway	GO:0002764	2	0.011
positive regulation of multicellular organismal process	GO:0051240	143	0.011
protein localization	GO:0008104	284	0.011
response to inorganic substance	GO:0010035	44	0.011
oxoacid metabolic process	GO:0043436	103	0.011
tripartite regional subdivision	GO:0007351	103	0.011
spinal cord patterning	GO:0021511	1	0.011
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.010
regulation of growth	GO:0040008	233	0.010
regulation of cell morphogenesis	GO:0022604	163	0.010
purine nucleotide catabolic process	GO:0006195	109	0.010
cellular response to ionizing radiation	GO:0071479	15	0.010
positive regulation of cellular protein metabolic process	GO:0032270	118	0.010
positive regulation of ras protein signal transduction	GO:0046579	43	0.010
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.010
synaptic transmission	GO:0007268	288	0.010
response to other organism	GO:0051707	293	0.010
female germ line cyst formation	GO:0048135	42	0.010

spn-B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of anatomical entity	DOID:7	0.273
bone marrow disease	DOID:4961	0.273
anemia	DOID:2355	0.273
aplastic anemia	DOID:12449	0.273
hematopoietic system disease	DOID:74	0.273
immune system disease	DOID:2914	0.273
congenital hypoplastic anemia	DOID:1342	0.221
breast cancer	DOID:1612	0.069	Human
thoracic cancer	DOID:5093	0.069	Human
disease of cellular proliferation	DOID:14566	0.069	Human
cancer	DOID:162	0.069	Human
organ system cancer	DOID:0050686	0.069	Human
cardiovascular system disease	DOID:1287	0.026
hypertension	DOID:10763	0.026
essential hypertension	DOID:10825	0.026
artery disease	DOID:0050828	0.026
vascular disease	DOID:178	0.026
glucose metabolism disease	DOID:4194	0.015
acquired metabolic disease	DOID:0060158	0.015
disease of metabolism	DOID:0014667	0.015
carbohydrate metabolism disease	DOID:0050013	0.015

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