Drosophila melanogaster

150 known processes

Pdf (Dmel_CG6496)

Pigment-dispersing factor

(Aliases: PAP,cPDH,anon-WO0140519.261,CG6496,Dmel\CG6496,pdf,anon-WO0140519.3,Drm-PDF,PDH,PDF,Drm-PDH,BcDNA:RH08487,Drm-pdf)

Pdf biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
circadian rhythmGO:00076231050.996
rhythmic behaviorGO:0007622760.987
circadian behaviorGO:0048512760.982
rhythmic processGO:00485111060.970
locomotor rhythmGO:0045475560.967
single organism behaviorGO:00447083910.941
multi organism behaviorGO:00517051750.883
mating behaviorGO:00076171060.833
gravitaxisGO:0042332260.810
regulation of behaviorGO:0050795750.808
matingGO:00076181200.799
reproductive behaviorGO:00190981220.676
locomotory behaviorGO:00076261760.639
sleepGO:0030431490.574
multi organism reproductive behaviorGO:00447051210.514
multicellular organismal reproductive behaviorGO:00330571100.336
entrainment of circadian clockGO:0009649160.316
response to gravityGO:0009629260.315
regulation of circadian rhythmGO:0042752490.277
regulation of circadian sleep wake cycleGO:0042749250.248
purine containing compound biosynthetic processGO:0072522300.247
multi multicellular organism processGO:00447061230.223
neurological system processGO:00508773580.168
regulation of cell proliferationGO:00421271630.160
detection of stimulusGO:00516061560.155
positive regulation of biosynthetic processGO:00098913160.154
purine containing compound metabolic processGO:00725211550.153
sensory perceptionGO:00076001960.153
regulation of circadian sleep wake cycle sleepGO:0045187210.144
taxisGO:00423303040.141
nucleobase containing small molecule metabolic processGO:00550861740.141
female mating behaviorGO:0060180300.134
organonitrogen compound metabolic processGO:19015643180.131
cell proliferationGO:00082832990.126
organophosphate metabolic processGO:00196371950.124
positive regulation of nitrogen compound metabolic processGO:00511733540.123
detection of stimulus involved in sensory perceptionGO:0050906920.122
response to oxygen containing compoundGO:19017002000.115
positive regulation of macromolecule biosynthetic processGO:00105572830.111
inter male aggressive behaviorGO:0002121600.105
negative regulation of response to stimulusGO:00485852580.100
anatomical structure homeostasisGO:0060249970.098
negative regulation of cellular biosynthetic processGO:00313272770.097
protein localizationGO:00081042840.090
adult behaviorGO:00305341370.090
regulation of transcription from rna polymerase ii promoterGO:00063573780.090
negative regulation of nucleobase containing compound metabolic processGO:00459342610.083
positive regulation of macromolecule metabolic processGO:00106044050.083
positive regulation of rna biosynthetic processGO:19026802660.079
positive regulation of cell growthGO:0030307190.078
ribose phosphate metabolic processGO:00196931450.078
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.077
enzyme linked receptor protein signaling pathwayGO:00071671790.077
behavioral response to ethanolGO:0048149490.072
response to organic substanceGO:00100332840.071
cellular response to chemical stimulusGO:00708871990.069
nucleoside phosphate metabolic processGO:00067531620.068
circadian sleep wake cycle processGO:0022410240.067
aggressive behaviorGO:0002118630.067
positive regulation of phosphate metabolic processGO:00459371390.064
organ growthGO:0035265560.059
developmental growthGO:00485892800.059
negative regulation of rna metabolic processGO:00512532510.058
nucleotide metabolic processGO:00091171610.058
regulation of immune system processGO:00026821760.058
positive regulation of signalingGO:00230562430.057
purine ribonucleotide metabolic processGO:00091501450.056
ribonucleotide metabolic processGO:00092591450.055
regulation of cellular component sizeGO:0032535980.054
response to abiotic stimulusGO:00096283410.053
epithelial tube morphogenesisGO:0060562880.053
transcription from rna polymerase ii promoterGO:00063663680.051
negative regulation of biosynthetic processGO:00098902770.049
regulation of molecular functionGO:00650092170.048
positive regulation of signal transductionGO:00099672230.048
regulation of growthGO:00400082330.047
carbohydrate derivative metabolic processGO:19011352170.047
response to temperature stimulusGO:00092661060.045
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.044
positive regulation of gene expressionGO:00106282900.044
cellular response to hormone stimulusGO:0032870440.044
positive regulation of nucleic acid templated transcriptionGO:19035082660.044
regulation of female receptivityGO:0045924240.043
epithelial cell differentiationGO:00308553220.043
cell growthGO:00160491080.042
larval behaviorGO:0030537420.042
response to alcoholGO:0097305950.041
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188170.040
detection of external stimulusGO:0009581660.040
positive regulation of rna metabolic processGO:00512542710.040
regulation of cell sizeGO:0008361630.039
macromolecular complex assemblyGO:00650032560.039
cellular response to peptideGO:1901653280.039
multicellular organism growthGO:0035264460.038
copulationGO:0007620260.037
eye developmentGO:00016543230.037
negative regulation of cellular metabolic processGO:00313243820.037
response to organonitrogen compoundGO:0010243750.037
positive regulation of response to stimulusGO:00485843230.036
positive regulation of cellular biosynthetic processGO:00313283160.035
entrainment of circadian clock by photoperiodGO:004315390.035
compound eye developmentGO:00487493070.035
cellular response to endogenous stimulusGO:0071495800.035
single organism biosynthetic processGO:00447112060.034
dendrite morphogenesisGO:00488131990.034
detection of light stimulusGO:0009583580.033
regulation of camp biosynthetic processGO:0030817120.033
positive regulation of protein metabolic processGO:00512471280.032
epithelial cell developmentGO:00020642740.032
multicellular organismal agingGO:00102591400.031
eye morphogenesisGO:00485922600.031
neuropeptide signaling pathwayGO:0007218450.031
positive regulation of growthGO:0045927750.031
localization of cellGO:00516742570.031
regulation of response to stressGO:00801342000.031
negative regulation of gene expressionGO:00106293870.031
growthGO:00400073590.030
camp biosynthetic processGO:0006171170.030
response to radiationGO:00093141550.030
regulation of intracellular signal transductionGO:19025312360.030
circadian sleep wake cycle sleepGO:0050802230.029
developmental maturationGO:00217001720.029
cellular response to organonitrogen compoundGO:0071417360.029
positive regulation of cell communicationGO:00106472500.029
regulation of epithelial cell differentiationGO:003085640.029
negative regulation of transcription dna templatedGO:00458922370.028
negative regulation of macromolecule biosynthetic processGO:00105582700.028
detection of abiotic stimulusGO:0009582660.028
dendrite developmentGO:00163582040.028
determination of adult lifespanGO:00083401370.028
regulation of cell cycleGO:00517262910.027
negative regulation of rna biosynthetic processGO:19026792400.027
positive regulation of nucleobase containing compound metabolic processGO:00459353320.026
muscle structure developmentGO:00610612240.026
tissue morphogenesisGO:00487292970.026
larval feeding behaviorGO:0030536150.025
cell deathGO:00082192790.025
organonitrogen compound biosynthetic processGO:19015661170.025
regulation of defense responseGO:00313471020.025
regulation of cellular protein metabolic processGO:00322682430.025
gland developmentGO:00487321910.025
feeding behaviorGO:0007631500.024
immune response regulating signaling pathwayGO:000276420.024
nucleoside phosphate biosynthetic processGO:1901293340.024
positive regulation of phosphorylationGO:0042327870.024
cellular amino acid metabolic processGO:0006520610.024
deathGO:00162652840.024
regulation of phosphate metabolic processGO:00192202100.024
organic substance transportGO:00717022570.023
immune system processGO:00023763470.023
startle responseGO:0001964160.023
response to nitrogen compoundGO:1901698900.023
negative regulation of nucleic acid templated transcriptionGO:19035072400.023
response to endogenous stimulusGO:00097191190.023
regulation of protein metabolic processGO:00512462560.023
catechol containing compound metabolic processGO:0009712100.023
small molecule metabolic processGO:00442813050.022
regulation of developmental growthGO:00486381740.022
response to ethanolGO:0045471590.022
response to peptide hormoneGO:0043434290.022
ribose phosphate biosynthetic processGO:0046390280.022
regulation of response to external stimulusGO:00321011150.022
response to insulinGO:0032868290.022
cell divisionGO:00513012480.022
response to heatGO:0009408630.022
circadian sleep wake cycleGO:0042745280.021
positive regulation of intracellular signal transductionGO:19025331160.021
regulation of purine nucleotide metabolic processGO:1900542620.021
male mating behaviorGO:0060179700.021
regulation of cell deathGO:00109411730.021
cellular protein modification processGO:00064644380.021
insulin receptor signaling pathwayGO:0008286250.021
positive regulation of transcription dna templatedGO:00458932660.021
limb developmentGO:006017310.020
protein complex assemblyGO:00064612000.020
chromatin organizationGO:00063252070.020
positive regulation of phosphorus metabolic processGO:00105621390.020
cyclic nucleotide biosynthetic processGO:0009190250.020
regulation of organ growthGO:0046620420.020
purine ribonucleoside triphosphate catabolic processGO:00092071080.020
nitrogen compound transportGO:0071705850.019
histone modificationGO:00165701060.019
agingGO:00075681430.019
regionalizationGO:00030024160.019
cellular response to organic substanceGO:00713101320.019
cellular response to nitrogen compoundGO:1901699510.019
homeostatic processGO:00425921990.019
immune responseGO:00069552460.019
kidney developmentGO:000182230.019
regulation of programmed cell deathGO:00430671520.019
positive regulation of developmental processGO:00510941430.019
sensory organ morphogenesisGO:00905962600.019
protein modification processGO:00362114380.019
purine nucleotide metabolic processGO:00061631460.018
organic substance catabolic processGO:19015753080.018
regulation of anatomical structure sizeGO:00900661630.018
cellular response to abiotic stimulusGO:0071214580.018
regulation of multi organism processGO:00439001310.018
tube developmentGO:00352952440.018
organelle fissionGO:00482853400.018
thermotaxisGO:0043052160.018
tube morphogenesisGO:00352391910.018
appendage morphogenesisGO:00351073970.018
regulation of cellular response to stressGO:0080135890.018
photoperiodismGO:0009648100.018
secretionGO:00469031090.018
chemotaxisGO:00069352490.018
cellular response to radiationGO:0071478520.017
mesenchymal cell differentiationGO:004876210.017
compound eye photoreceptor cell differentiationGO:00017511400.017
carbohydrate utilizationGO:000975810.017
negative regulation of developmental processGO:00510932010.017
regulation of transcription regulatory region dna bindingGO:200067730.017
organic acid metabolic processGO:00060821030.017
signal transduction by phosphorylationGO:00230141070.017
glycosyl compound metabolic processGO:19016571270.017
positive regulation of multicellular organismal processGO:00512401430.017
regulation of neurogenesisGO:00507671580.017
heart processGO:0003015370.017
cyclic nucleotide metabolic processGO:0009187280.017
compound eye morphogenesisGO:00017452490.017
terminal region determinationGO:0007362250.017
positive regulation of cyclic nucleotide metabolic processGO:003080190.017
response to light stimulusGO:00094161240.017
carboxylic acid metabolic processGO:0019752920.016
photoreceptor cell differentiationGO:00465301700.016
aromatic compound catabolic processGO:00194391660.016
regulation of female receptivity post matingGO:0046008170.016
response to extracellular stimulusGO:00099911160.016
regulation of catalytic activityGO:00507901850.016
sensory perception of soundGO:0007605560.016
positive regulation of purine nucleotide metabolic processGO:1900544550.016
regulation of adenylate cyclase activityGO:0045761120.016
connective tissue developmentGO:006144830.016
regulation of cell growthGO:0001558430.016
organelle fusionGO:0048284460.015
columnar cuboidal epithelial cell differentiationGO:00020652560.015
regulation of immune responseGO:00507761180.015
dna metabolic processGO:00062592270.015
central nervous system developmentGO:00074172010.015
proteolysisGO:00065081920.015
nucleoside catabolic processGO:00091641120.015
vesicle fusionGO:0006906190.015
olfactory behaviorGO:0042048970.015
carbohydrate derivative biosynthetic processGO:1901137850.015
oxoacid metabolic processGO:00434361030.015
apoptotic processGO:00069151590.015
regulation of cell developmentGO:00602842150.015
aromatic amino acid family metabolic processGO:000907230.015
regulation of cellular component biogenesisGO:00440872010.015
regulation of anatomical structure morphogenesisGO:00226032420.015
positive regulation of cellular component biogenesisGO:0044089800.015
cellular response to dna damage stimulusGO:00069742230.015
regulation of cell morphogenesisGO:00226041630.015
single organism membrane organizationGO:0044802930.015
regulation of nucleotide metabolic processGO:0006140620.014
protein complex biogenesisGO:00702712010.014
negative regulation of nucleotide biosynthetic processGO:003080930.014
neuron projection guidanceGO:00974852410.014
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.014
actin filament based processGO:00300292200.014
regulation of cell differentiationGO:00455953020.014
negative regulation of nitrogen compound metabolic processGO:00511722650.014
regulation of dna metabolic processGO:0051052340.014
negative regulation of insulin secretionGO:004667610.014
intracellular signal transductionGO:00355563000.014
ribonucleoside triphosphate catabolic processGO:00092031080.014
positive regulation of behaviorGO:0048520190.014
flight behaviorGO:0007629260.014
regulation of localizationGO:00328792750.014
regulation of multicellular organism growthGO:0040014400.014
chromosome organizationGO:00512763600.014
positive regulation of cellular protein metabolic processGO:00322701180.014
mitotic nuclear divisionGO:00070672130.014
cellular amine metabolic processGO:0044106120.014
molting cycle chitin based cuticleGO:0007591560.014
head developmentGO:00603221350.014
cell cycle checkpointGO:0000075950.014
macromolecule catabolic processGO:00090571610.013
regulation of neuron differentiationGO:00456641030.013
response to monosaccharideGO:003428440.013
establishment of localization in cellGO:00516494020.013
appendage developmentGO:00487364010.013
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathwayGO:001057970.013
branching morphogenesis of an epithelial tubeGO:0048754450.013
cell type specific apoptotic processGO:0097285380.013
purine nucleotide biosynthetic processGO:0006164290.013
positive regulation of i kappab kinase nf kappab signalingGO:004312310.013
programmed cell deathGO:00125012570.013
phagocytosisGO:00069092150.013
regulation of multicellular organismal developmentGO:20000264140.013
exocrine system developmentGO:00352721620.013
positive regulation of developmental growthGO:0048639620.013
phosphorylationGO:00163102940.013
organic cyclic compound catabolic processGO:19013611680.013
regulation of cellular amine metabolic processGO:003323830.013
purine nucleoside catabolic processGO:00061521120.013
cellular response to light stimulusGO:0071482370.013
regulation of apoptotic processGO:00429811300.013
cellular response to ethanolGO:007136140.013
heterocycle catabolic processGO:00467001660.013
respiratory system developmentGO:00605412130.013
regulation of cell morphogenesis involved in differentiationGO:0010769610.013
amine metabolic processGO:0009308120.013
ras protein signal transductionGO:0007265880.013
purine ribonucleoside triphosphate metabolic processGO:00092051190.013
intracellular receptor signaling pathwayGO:0030522190.012
nucleoside phosphate catabolic processGO:19012921100.012
response to other organismGO:00517072930.012
nucleocytoplasmic transportGO:0006913720.012
regulation of catabolic processGO:00098941700.012
response to peptideGO:1901652290.012
regulation of growth rateGO:004000930.012
response to hormoneGO:0009725450.012
regulation of epithelial cell proliferationGO:005067840.012
nucleoside metabolic processGO:00091161270.012
immune effector processGO:0002252980.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.012
ribonucleoside triphosphate metabolic processGO:00091991190.012
purine containing compound catabolic processGO:00725231120.012
negative regulation of cell deathGO:0060548810.012
adult locomotory behaviorGO:0008344760.012
immune response activating signal transductionGO:000275720.012
regulation of cellular ketone metabolic processGO:001056530.012
carbohydrate derivative catabolic processGO:19011361180.012
vesicle mediated transportGO:00161923810.012
cellular response to oxygen containing compoundGO:1901701790.012
regulation of gtpase activityGO:0043087440.012
cellular response to peptide hormone stimulusGO:0071375280.012
heart contractionGO:0060047260.011
axon ensheathmentGO:0008366100.011
regulation of protein catabolic processGO:0042176550.011
negative regulation of signal transductionGO:00099682060.011
purine ribonucleotide catabolic processGO:00091541090.011
purine nucleoside triphosphate catabolic processGO:00091461080.011
regulation of mitotic cell cycleGO:00073461900.011
regulation of phosphorus metabolic processGO:00511742100.011
positive regulation of cellular component organizationGO:00511301560.011
positive regulation of catalytic activityGO:00430851180.011
nucleotide biosynthetic processGO:0009165340.011
chromatin modificationGO:00165681470.011
positive regulation of dna metabolic processGO:0051054120.011
photoreceptor cell developmentGO:0042461960.011
limb morphogenesisGO:003510810.011
positive regulation of defense responseGO:0031349590.011
extrinsic apoptotic signaling pathwayGO:009719110.011
regulation of phosphorylationGO:00423251470.011
cellular catabolic processGO:00442483720.011
nephron tubule morphogenesisGO:007207830.011
gliogenesisGO:0042063800.011
camera type eye developmentGO:004301040.011
cell maturationGO:00484691440.011
dorsal ventral pattern formationGO:00099531330.011
positive regulation of programmed cell deathGO:0043068620.011
xenobiotic catabolic processGO:004217810.011
response to inorganic substanceGO:0010035440.011
positive regulation of immune responseGO:0050778630.011
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
purine nucleoside triphosphate metabolic processGO:00091441190.011
mesenchymal cell developmentGO:001403110.010
organonitrogen compound catabolic processGO:19015651280.010
synaptic transmissionGO:00072682880.010
response to oxidative stressGO:0006979860.010
single organism catabolic processGO:00447122280.010
neuronal action potentialGO:0019228100.010
regulation of cell cycle processGO:00105641810.010
regulation of protein modification processGO:00313991120.010
positive regulation of nucleotide metabolic processGO:0045981550.010
nephron developmentGO:007200630.010
gland morphogenesisGO:00226121450.010
rna splicing via transesterification reactionsGO:0000375730.010
hormone metabolic processGO:0042445330.010
membrane fusionGO:0061025420.010

Pdf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
disease of metabolismDOID:001466700.021
nervous system diseaseDOID:86300.019
eye and adnexa diseaseDOID:149200.012
sensory system diseaseDOID:005015500.012
musculoskeletal system diseaseDOID:1700.011
inherited metabolic disorderDOID:65500.010