Drosophila melanogaster

8 known processes

PHGPx (Dmel_CG12013)

CG12013 gene product from transcript CG12013-RC

(Aliases: CG12013,DmPHGPx,anon-WO0257455.17,Dmel\CG12013)

PHGPx biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to inorganic substanceGO:0010035440.945
response to oxidative stressGO:0006979860.910
cellular response to reactive oxygen speciesGO:0034614140.644
response to reactive oxygen speciesGO:0000302240.543
catabolic processGO:00090564090.441
cellular response to oxidative stressGO:0034599280.413
glutathione metabolic processGO:0006749370.403
regulation of anatomical structure morphogenesisGO:00226032420.385
sulfur compound metabolic processGO:0006790590.368
single organism biosynthetic processGO:00447112060.362
intracellular transportGO:00469072280.342
peptide metabolic processGO:0006518800.295
cellular response to chemical stimulusGO:00708871990.285
homeostatic processGO:00425921990.275
regulation of cell deathGO:00109411730.259
single organism intracellular transportGO:19025822070.246
cellular catabolic processGO:00442483720.245
organonitrogen compound metabolic processGO:19015643180.245
response to metal ionGO:0010038230.242
determination of adult lifespanGO:00083401370.207
oxidation reduction processGO:00551141230.196
response to abiotic stimulusGO:00096283410.186
deathGO:00162652840.185
membrane fusionGO:0061025420.181
protein localizationGO:00081042840.171
response to hydrogen peroxideGO:0042542110.151
regulation of cell cycleGO:00517262910.136
membrane organizationGO:00610241120.128
cell proliferationGO:00082832990.126
intracellular signal transductionGO:00355563000.123
organic acid metabolic processGO:00060821030.123
dna metabolic processGO:00062592270.121
programmed cell deathGO:00125012570.114
regulation of apoptotic processGO:00429811300.114
carbohydrate metabolic processGO:0005975820.114
regulation of cell morphogenesisGO:00226041630.112
cellular amide metabolic processGO:0043603800.110
cell deathGO:00082192790.104
organic substance catabolic processGO:19015753080.102
organic substance transportGO:00717022570.101
small molecule metabolic processGO:00442813050.097
monocarboxylic acid metabolic processGO:0032787290.095
response to oxygen containing compoundGO:19017002000.092
positive regulation of nucleic acid templated transcriptionGO:19035082660.090
organonitrogen compound biosynthetic processGO:19015661170.087
carboxylic acid metabolic processGO:0019752920.082
regulation of programmed cell deathGO:00430671520.082
positive regulation of biosynthetic processGO:00098913160.082
response to nutrient levelsGO:00316671140.079
negative regulation of rna metabolic processGO:00512532510.079
regulation of cellular localizationGO:00603411360.077
mitochondrion organizationGO:0007005650.074
regulation of cell proliferationGO:00421271630.073
regulation of cell shapeGO:00083601130.071
mitochondrial transportGO:000683980.071
response to organic substanceGO:00100332840.070
regulation of cellular ketone metabolic processGO:001056530.069
cellular response to inorganic substanceGO:007124180.069
regulation of organelle organizationGO:00330431960.068
single organism catabolic processGO:00447122280.068
cellular aldehyde metabolic processGO:0006081100.067
endosome transport via multivesicular body sorting pathwayGO:0032509120.067
establishment of localization in cellGO:00516494020.067
hydrogen peroxide catabolic processGO:004274460.067
regulation of intracellular signal transductionGO:19025312360.064
regulation of multicellular organismal developmentGO:20000264140.063
oxoacid metabolic processGO:00434361030.062
response to woundingGO:0009611940.062
rna processingGO:00063961470.061
cellular amino acid metabolic processGO:0006520610.060
cellular modified amino acid metabolic processGO:0006575450.057
cellular response to extracellular stimulusGO:0031668640.056
lipid metabolic processGO:00066291210.055
ketone biosynthetic processGO:0042181160.055
alcohol metabolic processGO:0006066250.055
carbohydrate derivative metabolic processGO:19011352170.054
cellular response to oxygen containing compoundGO:1901701790.053
epithelial cell differentiationGO:00308553220.052
wing disc morphogenesisGO:00074723440.051
positive regulation of reactive oxygen species metabolic processGO:200037900.050
regulation of localizationGO:00328792750.050
lipid modificationGO:0030258240.050
negative regulation of nucleobase containing compound metabolic processGO:00459342610.049
negative regulation of cell communicationGO:00106482230.049
negative regulation of programmed cell deathGO:0043069720.048
regulation of apoptotic signaling pathwayGO:2001233100.048
imaginal disc derived appendage developmentGO:00487373990.048
appendage morphogenesisGO:00351073970.047
single organism carbohydrate metabolic processGO:0044723720.047
positive regulation of response to stimulusGO:00485843230.047
response to oxygen radicalGO:000030530.046
response to organic cyclic compoundGO:0014070890.045
proteolysisGO:00065081920.044
cellular response to nutrient levelsGO:0031669620.043
salivary gland cell autophagic cell deathGO:0035071830.043
response to starvationGO:0042594970.042
regulation of anatomical structure sizeGO:00900661630.042
positive regulation of nitrogen compound metabolic processGO:00511733540.041
neurological system processGO:00508773580.041
positive regulation of cellular biosynthetic processGO:00313283160.041
regulation of cell developmentGO:00602842150.040
taxisGO:00423303040.040
negative regulation of signalingGO:00230572190.039
cellular ketone metabolic processGO:0042180240.039
cellular homeostasisGO:0019725800.038
developmental pigmentationGO:0048066680.038
metal ion homeostasisGO:0055065440.038
apoptotic processGO:00069151590.038
positive regulation of intracellular signal transductionGO:19025331160.037
regulation of response to stressGO:00801342000.037
regionalizationGO:00030024160.037
regulation of transportGO:00510491810.036
regulation of cellular component sizeGO:0032535980.036
response to extracellular stimulusGO:00099911160.036
cellular response to hydrogen peroxideGO:007030170.036
posttranscriptional regulation of gene expressionGO:00106081450.036
regulation of mitochondrion organizationGO:0010821120.036
positive regulation of macromolecule biosynthetic processGO:00105572830.035
single organism membrane organizationGO:0044802930.034
cellular response to dna damage stimulusGO:00069742230.034
negative regulation of nitrogen compound metabolic processGO:00511722650.033
cellular response to starvationGO:0009267610.033
cell adhesionGO:00071551360.032
muscle structure developmentGO:00610612240.032
nucleoside phosphate metabolic processGO:00067531620.032
cell agingGO:000756920.032
positive regulation of cell communicationGO:00106472500.031
sex differentiationGO:0007548810.030
localization of cellGO:00516742570.030
vitamin biosynthetic processGO:000911010.029
regulation of steroid metabolic processGO:001921820.029
imaginal disc derived appendage morphogenesisGO:00351143950.029
regulation of cell differentiationGO:00455953020.029
pyridine nucleotide metabolic processGO:001936220.028
wing disc pattern formationGO:0035222660.028
negative regulation of cellular component organizationGO:00511291080.028
purine containing compound metabolic processGO:00725211550.027
reactive oxygen species metabolic processGO:0072593220.027
appendage developmentGO:00487364010.027
negative regulation of nucleic acid templated transcriptionGO:19035072400.027
negative regulation of response to stimulusGO:00485852580.027
pigment biosynthetic processGO:0046148360.027
negative regulation of organelle organizationGO:0010639560.027
hydrogen peroxide metabolic processGO:004274360.027
chaeta developmentGO:0022416970.027
regulation of intracellular transportGO:0032386640.027
organophosphate metabolic processGO:00196371950.027
regulation of cellular response to stressGO:0080135890.027
regulation of mrna splicing via spliceosomeGO:0048024640.027
establishment or maintenance of cell polarityGO:00071631670.026
negative regulation of cell differentiationGO:00455961430.026
pigmentationGO:0043473750.026
regulation of mrna processingGO:0050684710.026
multicellular organismal agingGO:00102591400.025
negative regulation of cell cycleGO:00457861160.025
chemotaxisGO:00069352490.025
pigment metabolic processGO:0042440840.025
cellular response to external stimulusGO:0071496660.025
regulation of reactive oxygen species metabolic processGO:200037780.024
reproductive structure developmentGO:0048608740.024
developmental programmed cell deathGO:00106231380.024
regulation of cell morphogenesis involved in differentiationGO:0010769610.024
response to bacteriumGO:00096171980.024
transcription from rna polymerase ii promoterGO:00063663680.024
cell motilityGO:00488702510.024
negative regulation of cell deathGO:0060548810.024
autophagic cell deathGO:0048102830.024
telencephalon developmentGO:002153720.024
organic hydroxy compound biosynthetic processGO:1901617210.024
developmental growthGO:00485892800.023
regulation of phosphorylationGO:00423251470.023
protein modification processGO:00362114380.022
response to endogenous stimulusGO:00097191190.022
salivary gland developmentGO:00074311620.022
regulation of neurogenesisGO:00507671580.022
forebrain developmentGO:003090020.022
digestive tract morphogenesisGO:00485461270.022
cytoplasmic transportGO:00164821300.022
brain developmentGO:00074201200.021
response to decreased oxygen levelsGO:0036293580.021
agingGO:00075681430.021
negative regulation of gene expressionGO:00106293870.021
phosphorylationGO:00163102940.021
salivary gland morphogenesisGO:00074351450.021
regulation of protein metabolic processGO:00512462560.020
histolysisGO:00075591020.020
negative regulation of homeostatic processGO:003284520.020
morphogenesis of an epitheliumGO:00020092760.020
regulation of nervous system developmentGO:00519602480.020
biological adhesionGO:00226101380.020
steroid metabolic processGO:0008202200.020
organic hydroxy compound metabolic processGO:1901615830.020
spermatogenesisGO:00072832000.020
negative regulation of developmental processGO:00510932010.020
tissue deathGO:00162711020.020
positive regulation of transcription dna templatedGO:00458932660.019
post embryonic appendage morphogenesisGO:00351203850.019
negative regulation of rna biosynthetic processGO:19026792400.019
positive regulation of molecular functionGO:00440931360.019
tube morphogenesisGO:00352391910.019
cellular lipid metabolic processGO:0044255830.019
cellular component assembly involved in morphogenesisGO:00109271510.019
exocrine system developmentGO:00352721620.019
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.018
positive regulation of rna biosynthetic processGO:19026802660.018
regulation of notch signaling pathwayGO:00085931000.018
mrna processingGO:00063971040.018
wound healingGO:0042060750.018
endocytosisGO:00068973100.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.018
purine ribonucleotide metabolic processGO:00091501450.018
dendrite developmentGO:00163582040.018
epithelial cell developmentGO:00020642740.018
nucleotide metabolic processGO:00091171610.018
secondary metabolic processGO:0019748750.018
organic cyclic compound catabolic processGO:19013611680.018
response to temperature stimulusGO:00092661060.018
regulation of cellular component biogenesisGO:00440872010.018
response to oxygen levelsGO:0070482590.018
positive regulation of signal transductionGO:00099672230.017
cellular protein complex assemblyGO:0043623710.017
maintenance of cell polarityGO:0030011180.017
anatomical structure homeostasisGO:0060249970.017
negative regulation of biosynthetic processGO:00098902770.017
release of sequestered calcium ion into cytosolGO:005120910.017
embryonic morphogenesisGO:00485982060.017
negative regulation of cellular metabolic processGO:00313243820.017
small molecule catabolic processGO:0044282210.017
cellular ion homeostasisGO:0006873390.017
cellular protein modification processGO:00064644380.017
regulation of mrna metabolic processGO:1903311720.017
regulation of mapk cascadeGO:0043408920.017
positive regulation of nucleobase containing compound metabolic processGO:00459353320.017
response to radiationGO:00093141550.016
cellular response to decreased oxygen levelsGO:0036294300.016
regulation of dna metabolic processGO:0051052340.016
negative regulation of multicellular organismal processGO:00512411420.016
regulation of phosphate metabolic processGO:00192202100.016
dna integrity checkpointGO:0031570810.016
response to hypoxiaGO:0001666530.016
chorion containing eggshell formationGO:00073041050.016
cellular response to metal ionGO:007124860.016
ion transportGO:00068111450.016
response to heatGO:0009408630.016
protein transportGO:00150311550.016
inorganic cation transmembrane transportGO:0098662610.016
tube developmentGO:00352952440.016
response to calcium ionGO:005159210.015
positive regulation of cell deathGO:0010942690.015
small gtpase mediated signal transductionGO:0007264880.015
regulation of catabolic processGO:00098941700.015
positive regulation of cellular protein metabolic processGO:00322701180.015
aggressive behaviorGO:0002118630.015
regulation of rna splicingGO:0043484690.015
male gamete generationGO:00482322010.015
developmental maturationGO:00217001720.015
ameboidal type cell migrationGO:00016671510.015
cellular response to cadmium ionGO:007127660.015
regulation of molecular functionGO:00650092170.015
negative regulation of cell proliferationGO:0008285690.015
protein phosphorylationGO:00064681690.015
single organism behaviorGO:00447083910.015
mitochondrion degradationGO:000042280.015
positive regulation of rna metabolic processGO:00512542710.015
positive regulation of programmed cell deathGO:0043068620.014
male sex differentiationGO:0046661250.014
striated muscle cell differentiationGO:0051146900.014
regulation of cellular response to oxidative stressGO:190040740.014
cellular response to organic substanceGO:00713101320.014
response to other organismGO:00517072930.014
ribose phosphate metabolic processGO:00196931450.014
endosomal transportGO:0016197440.014
salivary gland histolysisGO:0035070880.014
glycosyl compound metabolic processGO:19016571270.014
positive regulation of macromolecule metabolic processGO:00106044050.014
muscle cell differentiationGO:00426921030.014
quinone metabolic processGO:190166110.014
response to monosaccharideGO:003428440.014
regulation of small gtpase mediated signal transductionGO:0051056930.014
ribonucleotide metabolic processGO:00092591450.014
signal transduction by phosphorylationGO:00230141070.014
positive regulation of mapk cascadeGO:0043410630.014
ras protein signal transductionGO:0007265880.014
negative regulation of sequestering of calcium ionGO:005128320.013
body morphogenesisGO:001017120.013
positive regulation of signalingGO:00230562430.013
eye pigment metabolic processGO:0042441330.013
thioester metabolic processGO:003538330.013
reproductive system developmentGO:0061458740.013
cellular response to oxygen levelsGO:0071453300.013
cellular macromolecule localizationGO:00707272200.013
regulation of ras protein signal transductionGO:0046578930.013
defense responseGO:00069523000.013
organelle fissionGO:00482853400.012
gland developmentGO:00487321910.012
negative regulation of apoptotic processGO:0043066630.012
carbohydrate biosynthetic processGO:0016051170.012
gonad developmentGO:0008406500.012
intracellular protein transportGO:00068861040.012
lipid oxidationGO:003444070.012
regulation of developmental growthGO:00486381740.012
negative regulation of cellular biosynthetic processGO:00313272770.012
negative regulation of molecular functionGO:0044092510.012
imaginal disc derived wing margin morphogenesisGO:0008587410.012
positive regulation of gene expressionGO:00106282900.012
cellular cation homeostasisGO:0030003380.012
regulation of cytoplasmic transportGO:1903649470.012
carboxylic acid biosynthetic processGO:0046394150.012
response to lipopolysaccharideGO:003249640.011
cellular protein localizationGO:00346131600.011
gastrulationGO:0007369700.011
cellular response to endogenous stimulusGO:0071495800.011
dendrite morphogenesisGO:00488131990.011
response to cadmium ionGO:004668690.011
polyol biosynthetic processGO:004617330.011
acyl coa metabolic processGO:000663730.011
regulation of neuron deathGO:1901214260.011
positive regulation of apoptotic processGO:0043065470.011
axonogenesisGO:00074092900.011
apoptotic signaling pathwayGO:0097190270.011
camera type eye developmentGO:004301040.011
regulation of cellular catabolic processGO:00313291570.011
mitotic spindle elongationGO:0000022810.011
mrna splicing via spliceosomeGO:0000398730.011
regulation of cellular protein metabolic processGO:00322682430.011
dna replicationGO:0006260480.011
androgen metabolic processGO:000820910.011
regulation of proteolysisGO:0030162870.011
protein complex biogenesisGO:00702712010.010
nucleobase containing small molecule metabolic processGO:00550861740.010
regulation of response to oxidative stressGO:190288240.010
development of primary sexual characteristicsGO:0045137500.010
response to external biotic stimulusGO:00432072930.010
autophagyGO:00069141080.010
sesquiterpenoid metabolic processGO:000671430.010
larval developmentGO:00021641040.010
organelle assemblyGO:00709251980.010
growthGO:00400073590.010
cell maturationGO:00484691440.010
primary alcohol metabolic processGO:003430820.010

PHGPx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.026
central nervous system diseaseDOID:33100.016
nervous system diseaseDOID:86300.016
neurodegenerative diseaseDOID:128900.016
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012