Drosophila melanogaster

0 known processes

Npc2f (Dmel_CG6164)

Niemann-Pick type C-2f

(Aliases: CG6164,npc2f,BcDNA:LP08842,Dmel\CG6164)

Npc2f biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sterol homeostasisGO:005509240.116
response to biotic stimulusGO:00096072940.085
response to external biotic stimulusGO:00432072930.053
defense response to other organismGO:00985422250.049
small molecule metabolic processGO:00442813050.043
defense response to bacteriumGO:00427421780.042
appendage developmentGO:00487364010.041
imaginal disc derived appendage morphogenesisGO:00351143950.039
post embryonic appendage morphogenesisGO:00351203850.038
imaginal disc derived appendage developmentGO:00487373990.037
positive regulation of response to stimulusGO:00485843230.036
appendage morphogenesisGO:00351073970.035
organonitrogen compound metabolic processGO:19015643180.035
organic acid metabolic processGO:00060821030.033
imaginal disc derived wing morphogenesisGO:00074763370.032
response to bacteriumGO:00096171980.032
wing disc morphogenesisGO:00074723440.031
cellular catabolic processGO:00442483720.031
positive regulation of nitrogen compound metabolic processGO:00511733540.031
immune system processGO:00023763470.030
intracellular signal transductionGO:00355563000.030
single organism behaviorGO:00447083910.030
defense responseGO:00069523000.030
catabolic processGO:00090564090.029
cellular amine metabolic processGO:0044106120.028
regionalizationGO:00030024160.027
response to other organismGO:00517072930.027
protein modification processGO:00362114380.027
open tracheal system developmentGO:00074242040.027
response to organic substanceGO:00100332840.027
epithelial cell developmentGO:00020642740.026
response to lipopolysaccharideGO:003249640.026
vesicle mediated transportGO:00161923810.025
cellular ketone metabolic processGO:0042180240.025
adult behaviorGO:00305341370.025
positive regulation of nucleobase containing compound metabolic processGO:00459353320.025
axonogenesisGO:00074092900.025
response to abiotic stimulusGO:00096283410.024
positive regulation of cell communicationGO:00106472500.024
organic substance catabolic processGO:19015753080.024
positive regulation of signalingGO:00230562430.023
taxisGO:00423303040.023
tissue morphogenesisGO:00487292970.023
axon guidanceGO:00074112330.023
positive regulation of signal transductionGO:00099672230.023
carboxylic acid metabolic processGO:0019752920.023
positive regulation of cellular biosynthetic processGO:00313283160.022
body morphogenesisGO:001017120.022
morphogenesis of an epitheliumGO:00020092760.022
negative regulation of signal transductionGO:00099682060.022
axon developmentGO:00615642970.022
acetylcholine metabolic processGO:000829120.022
epithelial cell differentiationGO:00308553220.021
cholesterol homeostasisGO:004263230.021
columnar cuboidal epithelial cell developmentGO:00020662490.021
organelle fissionGO:00482853400.021
homeostatic processGO:00425921990.021
regulation of cellular ketone metabolic processGO:001056530.021
respiratory system developmentGO:00605412130.021
regulation of cell cycleGO:00517262910.021
tube morphogenesisGO:00352391910.021
single organism catabolic processGO:00447122280.021
camera type eye developmentGO:004301040.021
endocytosisGO:00068973100.020
phagocytosisGO:00069092150.020
positive regulation of biosynthetic processGO:00098913160.020
cell cycle phase transitionGO:00447701400.020
response to nutrient levelsGO:00316671140.020
regulation of cellular amine metabolic processGO:003323830.020
hormone catabolic processGO:004244730.020
amine metabolic processGO:0009308120.020
nuclear divisionGO:00002803320.020
synaptic transmissionGO:00072682880.020
columnar cuboidal epithelial cell differentiationGO:00020652560.020
oxoacid metabolic processGO:00434361030.020
cellular protein modification processGO:00064644380.020
compound eye morphogenesisGO:00017452490.020
steroid catabolic processGO:000670610.019
forebrain developmentGO:003090020.019
neurotransmitter metabolic processGO:004213320.019
response to organophosphorusGO:004668320.019
single organism biosynthetic processGO:00447112060.019
matingGO:00076181200.019
eye developmentGO:00016543230.019
cell cell signaling involved in cell fate commitmentGO:00451682100.019
aromatic compound catabolic processGO:00194391660.019
cell proliferationGO:00082832990.019
gland morphogenesisGO:00226121450.019
phosphorylationGO:00163102940.019
cellular response to dna damage stimulusGO:00069742230.019
regulation of multicellular organismal developmentGO:20000264140.019
organic cyclic compound catabolic processGO:19013611680.019
cell deathGO:00082192790.018
organic substance transportGO:00717022570.018
chromosome segregationGO:00070591570.018
tube developmentGO:00352952440.018
ovarian follicle cell developmentGO:00307072480.018
cellular amino acid metabolic processGO:0006520610.018
regulation of cellular amino acid metabolic processGO:000652100.018
multi organism behaviorGO:00517051750.018
positive regulation of rna biosynthetic processGO:19026802660.018
transcription from rna polymerase ii promoterGO:00063663680.018
heterocycle catabolic processGO:00467001660.018
regulation of localizationGO:00328792750.018
protein localizationGO:00081042840.018
negative regulation of cell communicationGO:00106482230.018
developmental growthGO:00485892800.017
neuron projection guidanceGO:00974852410.017
regulation of cellular protein metabolic processGO:00322682430.017
salivary gland developmentGO:00074311620.017
lipid metabolic processGO:00066291210.017
cellular nitrogen compound catabolic processGO:00442701650.017
positive regulation of nucleic acid templated transcriptionGO:19035082660.017
regulation of catalytic activityGO:00507901850.017
mitotic cell cycle phase transitionGO:00447721380.017
regulation of molecular functionGO:00650092170.017
salivary gland morphogenesisGO:00074351450.017
response to extracellular stimulusGO:00099911160.017
non sensory hair organizationGO:0035316470.017
cell recognitionGO:00080371020.017
defense response to gram negative bacteriumGO:0050829940.017
eye morphogenesisGO:00485922600.017
negative regulation of response to stimulusGO:00485852580.016
sensory organ morphogenesisGO:00905962600.016
response to oxygen containing compoundGO:19017002000.016
lateral inhibitionGO:00463312060.016
regulation of intracellular signal transductionGO:19025312360.016
connective tissue developmentGO:006144830.016
actin filament based processGO:00300292200.016
regulation of multi organism processGO:00439001310.016
positive regulation of rna metabolic processGO:00512542710.016
medium chain fatty acid metabolic processGO:005179110.016
exocrine system developmentGO:00352721620.016
positive regulation of macromolecule metabolic processGO:00106044050.016
acetate ester metabolic processGO:190061920.016
compound eye developmentGO:00487493070.016
neuron recognitionGO:00080381010.016
negative regulation of gene expressionGO:00106293870.016
response to alcoholGO:0097305950.016
carbohydrate derivative metabolic processGO:19011352170.016
positive regulation of transcription dna templatedGO:00458932660.016
dna integrity checkpointGO:0031570810.016
localization of cellGO:00516742570.015
response to light stimulusGO:00094161240.015
purine containing compound metabolic processGO:00725211550.015
regulation of anatomical structure sizeGO:00900661630.015
regulation of transcription from rna polymerase ii promoterGO:00063573780.015
developmental maturationGO:00217001720.015
regulation of tube architecture open tracheal systemGO:0035152680.015
programmed cell deathGO:00125012570.015
regulation of cell differentiationGO:00455953020.015
agingGO:00075681430.015
proteolysisGO:00065081920.015
response to starvationGO:0042594970.015
nucleoside phosphate metabolic processGO:00067531620.015
positive regulation of cellular catabolic processGO:0031331950.015
telencephalon developmentGO:002153720.015
regulation of catabolic processGO:00098941700.015
negative regulation of signalingGO:00230572190.015
acetylcholine catabolic processGO:000658110.015
nucleobase containing compound catabolic processGO:00346551650.015
wnt signaling pathwayGO:0016055980.015
regulation of phosphate metabolic processGO:00192202100.015
macromolecule catabolic processGO:00090571610.015
negative regulation of nitrogen compound metabolic processGO:00511722650.015
positive regulation of macromolecule biosynthetic processGO:00105572830.015
regulation of phosphorus metabolic processGO:00511742100.015
response to glucoseGO:000974920.015
growthGO:00400073590.015
vitamin biosynthetic processGO:000911010.015
regulation of developmental growthGO:00486381740.015
response to radiationGO:00093141550.015
ameboidal type cell migrationGO:00016671510.014
tissue migrationGO:00901301550.014
purine ribonucleotide metabolic processGO:00091501450.014
negative regulation of cellular metabolic processGO:00313243820.014
mitotic dna integrity checkpointGO:0044774750.014
neurological system processGO:00508773580.014
cellular component assembly involved in morphogenesisGO:00109271510.014
xenobiotic catabolic processGO:004217810.014
gland developmentGO:00487321910.014
reproductive behaviorGO:00190981220.014
cellular biogenic amine catabolic processGO:004240210.014
determination of adult lifespanGO:00083401370.014
regulation of cellular component biogenesisGO:00440872010.014
regulation of mitotic cell cycleGO:00073461900.014
cell divisionGO:00513012480.014
nucleobase containing small molecule metabolic processGO:00550861740.014
multicellular organismal agingGO:00102591400.014
regulation of mitotic cell cycle phase transitionGO:19019901300.014
sensory perception of chemical stimulusGO:00076061160.014
female meiotic divisionGO:0007143700.014
purine nucleotide metabolic processGO:00061631460.014
response to endogenous stimulusGO:00097191190.014
gene silencingGO:00164581380.014
spermatogenesisGO:00072832000.014
insecticide metabolic processGO:001714320.014
male gamete generationGO:00482322010.014
cell migrationGO:00164772380.014
chemical homeostasisGO:0048878920.014
segmentationGO:00352822070.013
organophosphate metabolic processGO:00196371950.013
estrogen metabolic processGO:000821010.013
small gtpase mediated signal transductionGO:0007264880.013
dorsal ventral pattern formationGO:00099531330.013
cell cycle checkpointGO:0000075950.013
vitamin metabolic processGO:000676620.013
positive regulation of gene expressionGO:00106282900.013
neuropeptide signaling pathwayGO:0007218450.013
deathGO:00162652840.013
biological adhesionGO:00226101380.013
response to monosaccharideGO:003428440.013
cellular macromolecule catabolic processGO:00442651360.013
kidney developmentGO:000182230.013
skin developmentGO:0043588650.013
wound healingGO:0042060750.013
benzene containing compound metabolic processGO:004253730.013
polyol biosynthetic processGO:004617330.013
immune responseGO:00069552460.013
humoral immune responseGO:00069591170.013
ribose phosphate metabolic processGO:00196931450.013
negative regulation of developmental processGO:00510932010.013
response to hexoseGO:000974630.013
cellular lipid metabolic processGO:0044255830.013
cellular response to ethanolGO:007136140.013
peptidyl proline hydroxylationGO:001951110.013
molting cycle chitin based cuticleGO:0007591560.013
cellular macromolecule localizationGO:00707272200.013
cell motilityGO:00488702510.013
protein transportGO:00150311550.013
activation of innate immune responseGO:000221840.013
hindbrain developmentGO:003090220.013
embryonic pattern specificationGO:00098801740.012
posttranscriptional regulation of gene expressionGO:00106081450.012
innate immune responseGO:00450871440.012
positive regulation of cell motilityGO:200014730.012
mitotic g2 dna damage checkpointGO:0007095690.012
ras protein signal transductionGO:0007265880.012
synaptic target recognitionGO:0008039450.012
regulation of synapse structure and activityGO:00508031280.012
lipid localizationGO:0010876540.012
mitotic g2 m transition checkpointGO:0044818700.012
regulation of hydrolase activityGO:0051336970.012
blastoderm segmentationGO:00073501590.012
cellular response to biotic stimulusGO:007121640.012
establishment or maintenance of cell polarityGO:00071631670.012
acylglycerol catabolic processGO:004646430.012
choline catabolic processGO:004242610.012
positive regulation of molecular functionGO:00440931360.012
positive regulation of cellular amine metabolic processGO:003324000.012
androgen metabolic processGO:000820910.012
regulation of cellular catabolic processGO:00313291570.012
establishment of localization in cellGO:00516494020.012
organonitrogen compound catabolic processGO:19015651280.012
negative regulation of cell cycle phase transitionGO:19019881030.012
chaeta developmentGO:0022416970.012
embryonic development via the syncytial blastodermGO:00017001480.012
camera type eye morphogenesisGO:004859320.012
intracellular transportGO:00469072280.012
regulation of immune system processGO:00026821760.012
positive regulation of catalytic activityGO:00430851180.012
cellular response to chemical stimulusGO:00708871990.012
g2 dna damage checkpointGO:0031572690.012
establishment of protein localizationGO:00451841630.012
multicellular organismal reproductive behaviorGO:00330571100.012
positive regulation of phosphorus metabolic processGO:00105621390.012
regulation of transportGO:00510491810.012
nucleotide metabolic processGO:00091171610.012
monocarboxylic acid transportGO:001571830.012
secondary metabolite catabolic processGO:009048710.012
multi multicellular organism processGO:00447061230.012
negative regulation of cell cycleGO:00457861160.012
eggshell formationGO:00307031050.012
mitotic cell cycle checkpointGO:0007093880.012
protein hydroxylationGO:001812610.012
l glutamate importGO:005193810.012
peripheral nervous system developmentGO:0007422520.012
positive regulation of phosphate metabolic processGO:00459371390.011
salivary gland cell autophagic cell deathGO:0035071830.011
single organism cellular localizationGO:19025801800.011
organelle assemblyGO:00709251980.011
peptidyl amino acid modificationGO:00181931050.011
apoptotic processGO:00069151590.011
purine containing compound catabolic processGO:00725231120.011
limb developmentGO:006017310.011
digestive tract morphogenesisGO:00485461270.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
positive regulation of cell migrationGO:003033520.011
regulation of gene expression epigeneticGO:00400291280.011
mrna metabolic processGO:00160711240.011
regulation of protein metabolic processGO:00512462560.011
regulation of epithelial cell proliferationGO:005067840.011
cellular macromolecular complex assemblyGO:00346221530.011
mesenchymal cell differentiationGO:004876210.011
mitotic nuclear divisionGO:00070672130.011
regulation of response to external stimulusGO:00321011150.011
regulation of response to stressGO:00801342000.011
protein phosphorylationGO:00064681690.011
imaginal disc pattern formationGO:0007447910.011
hematopoietic progenitor cell differentiationGO:000224410.011
regulation of growthGO:00400082330.011
choline metabolic processGO:001969510.011
dna damage checkpointGO:0000077780.011
amine catabolic processGO:000931010.011
maintenance of locationGO:0051235730.011
response to woundingGO:0009611940.011
immune response regulating signaling pathwayGO:000276420.011
synapse organizationGO:00508081960.011
regulation of anatomical structure morphogenesisGO:00226032420.011
negative regulation of cell cycle processGO:00109481090.011
purine ribonucleoside metabolic processGO:00461281270.011
negative regulation of macromolecule biosynthetic processGO:00105582700.011
chemotaxisGO:00069352490.011
extrinsic apoptotic signaling pathwayGO:009719110.011
antimicrobial humoral responseGO:0019730990.011
tissue deathGO:00162711020.011
ion transportGO:00068111450.011
immune response activating signal transductionGO:000275720.011
cellular response to lipopolysaccharideGO:007122230.011
regulation of cell cycle processGO:00105641810.011
actin cytoskeleton organizationGO:00300362060.011
ethanolamine containing compound metabolic processGO:004243940.011
dendrite morphogenesisGO:00488131990.011
g protein coupled receptor signaling pathwayGO:00071861360.011
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.011
oxidation reduction processGO:00551141230.011
spermatid differentiationGO:00485151140.011
peptide metabolic processGO:0006518800.011
mesoderm developmentGO:0007498780.011
digestive tract developmentGO:00485651490.011
positive regulation of catabolic processGO:00098961050.011
organonitrogen compound biosynthetic processGO:19015661170.011
cytoplasmic transportGO:00164821300.011
positive regulation of lipid metabolic processGO:004583440.011
cellular response to organic substanceGO:00713101320.010
leg disc developmentGO:0035218920.010
cellular response to carbohydrate stimulusGO:007132240.010
negative regulation of cellular biosynthetic processGO:00313272770.010
limb morphogenesisGO:003510810.010
mesenchymal cell developmentGO:001403110.010
l amino acid importGO:004309220.010
organic hydroxy compound metabolic processGO:1901615830.010
regulation of apoptotic processGO:00429811300.010
single organism intracellular transportGO:19025822070.010
spinal cord developmentGO:002151010.010
response to copper ionGO:004668840.010
regulation of cell developmentGO:00602842150.010
actin filament organizationGO:00070151260.010
cellular response to hexose stimulusGO:007133110.010
regulation of cell deathGO:00109411730.010
gene silencing by rnaGO:0031047570.010
chemosensory behaviorGO:00076351060.010
hair cell differentiationGO:0035315470.010
organophosphate catabolic processGO:00464341120.010
protein processingGO:0016485680.010
secretionGO:00469031090.010
response to alkaloidGO:0043279260.010
regulation of tube size open tracheal systemGO:0035151430.010
protein maturationGO:0051604710.010
negative regulation of multicellular organismal processGO:00512411420.010
regulation of programmed cell deathGO:00430671520.010
cellular protein localizationGO:00346131600.010
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.010
regulation of i kappab kinase nf kappab signalingGO:004312220.010

Npc2f disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.027
nervous system diseaseDOID:86300.017
cardiovascular system diseaseDOID:128700.016
vascular diseaseDOID:17800.016
cancerDOID:16200.013
disease of cellular proliferationDOID:1456600.013
artery diseaseDOID:005082800.013
hypertensionDOID:1076300.013
musculoskeletal system diseaseDOID:1700.012
inherited metabolic disorderDOID:65500.012
disease of metabolismDOID:001466700.012
essential hypertensionDOID:1082500.012
sensory system diseaseDOID:005015500.011
organ system cancerDOID:005068600.010