Drosophila melanogaster

31 known processes

GRHR (Dmel_CG11325)

Gonadotropin-releasing hormone receptor

(Aliases: DGRHR,AKHR,Akhr,DAKHR,BEST:GH19447,CG11325,GnRHR,GRHR/CG11325,Dmel\CG11325,DAKHR-1)

GRHR biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
acylglycerol catabolic processGO:004646430.779
regulation of lipid storageGO:0010883220.542
triglyceride catabolic processGO:001943330.476
lipid catabolic processGO:0016042210.309
chemical homeostasisGO:0048878920.219
triglyceride metabolic processGO:0006641120.198
neutral lipid biosynthetic processGO:004646020.182
lipid homeostasisGO:0055088330.181
acylglycerol biosynthetic processGO:004646320.166
positive regulation of lipid storageGO:001088440.156
regulation of sequestering of triglycerideGO:001088930.154
acylglycerol metabolic processGO:0006639120.154
lipid metabolic processGO:00066291210.137
imaginal disc derived wing morphogenesisGO:00074763370.133
imaginal disc derived appendage morphogenesisGO:00351143950.128
triglyceride biosynthetic processGO:001943220.128
neutral lipid catabolic processGO:004646130.127
cellular catabolic processGO:00442483720.120
glycerolipid catabolic processGO:004650330.114
neuropeptide signaling pathwayGO:0007218450.113
Fly
organic substance transportGO:00717022570.101
maintenance of locationGO:0051235730.100
cellular lipid metabolic processGO:0044255830.097
wing disc morphogenesisGO:00074723440.094
neutral lipid metabolic processGO:0006638120.094
glycerolipid metabolic processGO:0046486340.090
response to starvationGO:0042594970.087
protein localizationGO:00081042840.087
regulation of localizationGO:00328792750.086
post embryonic appendage morphogenesisGO:00351203850.080
imaginal disc derived appendage developmentGO:00487373990.079
small molecule metabolic processGO:00442813050.078
positive regulation of lipid metabolic processGO:004583440.077
lipid storageGO:0019915380.076
lipid localizationGO:0010876540.075
appendage morphogenesisGO:00351073970.071
programmed cell deathGO:00125012570.063
cellular lipid catabolic processGO:0044242160.060
salivary gland morphogenesisGO:00074351450.059
cellular protein localizationGO:00346131600.057
homeostatic processGO:00425921990.056
agingGO:00075681430.056
cellular metal ion homeostasisGO:0006875310.054
sterol homeostasisGO:005509240.051
salivary gland developmentGO:00074311620.050
exocrine system developmentGO:00352721620.048
appendage developmentGO:00487364010.047
tissue deathGO:00162711020.046
developmental programmed cell deathGO:00106231380.045
single organism catabolic processGO:00447122280.044
deathGO:00162652840.043
cation homeostasisGO:0055080510.042
anion homeostasisGO:005508130.040
gland developmentGO:00487321910.040
regulation of mitotic cell cycleGO:00073461900.039
cholesterol homeostasisGO:004263230.038
response to abiotic stimulusGO:00096283410.038
regulation of cell cycleGO:00517262910.038
response to alcoholGO:0097305950.037
Fly
cellular cation homeostasisGO:0030003380.037
cellular protein modification processGO:00064644380.037
cell deathGO:00082192790.037
divalent inorganic cation homeostasisGO:0072507290.037
lipid biosynthetic processGO:0008610460.036
oxoacid metabolic processGO:00434361030.036
organic substance catabolic processGO:19015753080.036
cellular response to lipopolysaccharideGO:007122230.035
autophagic cell deathGO:0048102830.035
negative regulation of cellular biosynthetic processGO:00313272770.032
cellular divalent inorganic cation homeostasisGO:0072503230.032
response to nutrient levelsGO:00316671140.031
negative regulation of nucleic acid templated transcriptionGO:19035072400.031
macromolecular complex assemblyGO:00650032560.031
response to organic substanceGO:00100332840.031
Zebrafish Fly
organic acid metabolic processGO:00060821030.031
regulation of cell differentiationGO:00455953020.030
cellular ion homeostasisGO:0006873390.030
phospholipid homeostasisGO:005509110.029
response to biotic stimulusGO:00096072940.029
triglyceride homeostasisGO:0070328180.029
fat soluble vitamin biosynthetic processGO:004236210.029
endocytosisGO:00068973100.029
lipid modificationGO:0030258240.028
response to lipopolysaccharideGO:003249640.028
metal ion homeostasisGO:0055065440.028
taxisGO:00423303040.028
catabolic processGO:00090564090.027
multicellular organismal agingGO:00102591400.027
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.027
salivary gland histolysisGO:0035070880.027
positive regulation of signalingGO:00230562430.027
establishment of localization in cellGO:00516494020.027
regulation of lipid metabolic processGO:0019216150.027
developmental growthGO:00485892800.026
nitrogen compound transportGO:0071705850.026
positive regulation of cellular catabolic processGO:0031331950.026
immune system processGO:00023763470.026
positive regulation of lipid catabolic processGO:005099610.026
defense response to bacteriumGO:00427421780.026
sensory perceptionGO:00076001960.026
organonitrogen compound metabolic processGO:19015643180.025
cell recognitionGO:00080371020.025
regulation of transcription from rna polymerase ii promoterGO:00063573780.024
response to extracellular stimulusGO:00099911160.024
g protein coupled receptor signaling pathwayGO:00071861360.024
single organism biosynthetic processGO:00447112060.024
spermatogenesisGO:00072832000.024
cellular macromolecule localizationGO:00707272200.024
determination of adult lifespanGO:00083401370.024
telencephalon developmentGO:002153720.024
chemosensory behaviorGO:00076351060.023
regulation of cell deathGO:00109411730.023
cholesterol transportGO:003030120.023
apoptotic processGO:00069151590.023
negative regulation of rna metabolic processGO:00512532510.023
cellular response to chemical stimulusGO:00708871990.023
Zebrafish Fly
histolysisGO:00075591020.023
open tracheal system developmentGO:00074242040.023
negative regulation of biosynthetic processGO:00098902770.023
oxidation reduction processGO:00551141230.023
forebrain developmentGO:003090020.022
positive regulation of cell communicationGO:00106472500.022
regulation of catabolic processGO:00098941700.022
cellular homeostasisGO:0019725800.022
transcription from rna polymerase ii promoterGO:00063663680.022
mitochondrion organizationGO:0007005650.022
acetylcholine metabolic processGO:000829120.022
phagocytosisGO:00069092150.021
cellular calcium ion homeostasisGO:0006874210.021
regulation of molecular functionGO:00650092170.021
alcohol metabolic processGO:0006066250.021
connective tissue developmentGO:006144830.021
negative regulation of nitrogen compound metabolic processGO:00511722650.021
regulation of organelle organizationGO:00330431960.021
cellular ketone metabolic processGO:0042180240.021
response to woundingGO:0009611940.021
defense response to other organismGO:00985422250.021
salivary gland cell autophagic cell deathGO:0035071830.020
organophosphate metabolic processGO:00196371950.020
regulation of protein metabolic processGO:00512462560.020
establishment of protein localizationGO:00451841630.020
calcium ion homeostasisGO:0055074230.020
response to light stimulusGO:00094161240.020
regulation of cellular ketone metabolic processGO:001056530.019
cellular response to biotic stimulusGO:007121640.019
regulation of multicellular organismal developmentGO:20000264140.019
cellular amine metabolic processGO:0044106120.019
antimicrobial humoral responseGO:0019730990.019
cellular response to heatGO:0034605240.019
carboxylic acid metabolic processGO:0019752920.019
positive regulation of gene expressionGO:00106282900.019
protein complex assemblyGO:00064612000.019
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.019
body morphogenesisGO:001017120.019
defense responseGO:00069523000.019
vesicle mediated transportGO:00161923810.018
cellular response to oxygen containing compoundGO:1901701790.018
Zebrafish Fly
negative regulation of macromolecule biosynthetic processGO:00105582700.018
protein modification processGO:00362114380.018
eye photoreceptor cell developmentGO:0042462810.018
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.018
positive regulation of nucleic acid templated transcriptionGO:19035082660.018
lipid particle organizationGO:003438970.018
regulation of tube architecture open tracheal systemGO:0035152680.018
immune responseGO:00069552460.018
cellular response to starvationGO:0009267610.018
choline catabolic processGO:004242610.018
response to monosaccharideGO:003428440.018
positive regulation of apoptotic signaling pathwayGO:200123540.018
regulation of transportGO:00510491810.017
choline metabolic processGO:001969510.017
positive regulation of signal transductionGO:00099672230.017
acetylcholine catabolic processGO:000658110.017
regulation of cellular amine metabolic processGO:003323830.017
extrinsic apoptotic signaling pathwayGO:009719110.017
gland morphogenesisGO:00226121450.017
regulation of cellular catabolic processGO:00313291570.017
response to oxygen containing compoundGO:19017002000.016
Zebrafish Fly
positive regulation of rna biosynthetic processGO:19026802660.016
nucleobase containing small molecule metabolic processGO:00550861740.016
regulation of microtubule cytoskeleton organizationGO:0070507410.016
dorsal ventral pattern formationGO:00099531330.016
cellular response to organic substanceGO:00713101320.016
Zebrafish Fly
response to radiationGO:00093141550.016
response to glucoseGO:000974920.016
wnt signaling pathwayGO:0016055980.016
protein transportGO:00150311550.016
regulation of catalytic activityGO:00507901850.016
response to external biotic stimulusGO:00432072930.015
response to other organismGO:00517072930.015
cellular response to molecule of bacterial originGO:007121930.015
response to desiccationGO:000926930.015
adult behaviorGO:00305341370.015
Fly
ion homeostasisGO:0050801550.015
eye developmentGO:00016543230.015
regulation of epithelial cell differentiationGO:003085640.015
positive regulation of molecular functionGO:00440931360.015
positive regulation of multicellular organismal processGO:00512401430.015
positive regulation of cell deathGO:0010942690.015
detection of stimulusGO:00516061560.015
positive regulation of cell migrationGO:003033520.015
tissue morphogenesisGO:00487292970.015
response to water deprivationGO:000941440.015
respiratory system developmentGO:00605412130.015
response to sterolGO:0036314340.015
single organism behaviorGO:00447083910.015
Fly
negative regulation of developmental processGO:00510932010.015
defense response to gram negative bacteriumGO:0050829940.014
positive regulation of programmed cell deathGO:0043068620.014
carbohydrate derivative metabolic processGO:19011352170.014
cellular response to nutrient levelsGO:0031669620.014
negative regulation of mitotic cell cycle phase transitionGO:19019911030.014
phosphatidic acid metabolic processGO:004647310.014
eye pigment metabolic processGO:0042441330.014
wound healingGO:0042060750.014
positive regulation of response to stimulusGO:00485843230.014
response to organic cyclic compoundGO:0014070890.014
regulation of cellular amino acid metabolic processGO:000652100.014
adult locomotory behaviorGO:0008344760.014
negative regulation of gene expressionGO:00106293870.014
vitamin metabolic processGO:000676620.014
regulation of cell cycle phase transitionGO:19019871300.014
mesenchymal cell developmentGO:001403110.014
positive regulation of developmental processGO:00510941430.014
cell maturationGO:00484691440.014
neurotransmitter catabolic processGO:004213510.014
single organism intracellular transportGO:19025822070.014
cellular response to hormone stimulusGO:0032870440.013
Zebrafish
camera type eye developmentGO:004301040.013
cell cycle phase transitionGO:00447701400.013
organelle assemblyGO:00709251980.013
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.013
chromosome organizationGO:00512763600.013
acylglycerol homeostasisGO:0055090190.013
regionalizationGO:00030024160.013
positive regulation of catalytic activityGO:00430851180.013
central nervous system developmentGO:00074172010.013
negative regulation of cell differentiationGO:00455961430.013
ethanolamine containing compound metabolic processGO:004243940.013
cellular response to radiationGO:0071478520.013
androgen metabolic processGO:000820910.013
heart processGO:0003015370.013
larval midgut histolysisGO:0035069220.013
negative regulation of cell deathGO:0060548810.013
growthGO:00400073590.013
biological adhesionGO:00226101380.013
fatty acid beta oxidationGO:000663560.013
neuron projection guidanceGO:00974852410.013
actin cytoskeleton organizationGO:00300362060.012
positive regulation of macromolecule biosynthetic processGO:00105572830.012
detection of chemical stimulusGO:0009593930.012
leg disc morphogenesisGO:0007478800.012
cell motilityGO:00488702510.012
hematopoietic or lymphoid organ developmentGO:0048534570.012
cellular response to abiotic stimulusGO:0071214580.012
compound eye photoreceptor cell differentiationGO:00017511400.012
protein complex biogenesisGO:00702712010.012
regulation of programmed cell deathGO:00430671520.012
positive regulation of cell motilityGO:200014730.012
mesenchymal cell differentiationGO:004876210.012
response to organophosphorusGO:004668320.012
detection of visible lightGO:0009584380.012
amine metabolic processGO:0009308120.012
negative regulation of response to stimulusGO:00485852580.012
negative regulation of rna biosynthetic processGO:19026792400.012
positive regulation of catabolic processGO:00098961050.012
fat soluble vitamin metabolic processGO:000677510.012
positive regulation of rna metabolic processGO:00512542710.012
response to hexoseGO:000974630.012
protein importGO:0017038550.012
ovarian follicle cell developmentGO:00307072480.012
non sensory hair organizationGO:0035316470.012
neurotransmitter metabolic processGO:004213320.012
monocarboxylic acid transportGO:001571830.012
retina development in camera type eyeGO:006004140.011
phototaxisGO:0042331210.011
regulation of epithelial cell proliferationGO:005067840.011
compound eye photoreceptor developmentGO:0042051780.011
negative regulation of cell communicationGO:00106482230.011
negative regulation of growthGO:0045926840.011
regulation of mitotic cell cycle phase transitionGO:19019901300.011
negative regulation of mitotic cell cycleGO:00459301090.011
negative regulation of cellular metabolic processGO:00313243820.011
cellular response to endogenous stimulusGO:0071495800.011
Zebrafish
positive regulation of cell differentiationGO:0045597640.011
regulation of anatomical structure morphogenesisGO:00226032420.011
ribonucleotide metabolic processGO:00092591450.011
positive regulation of transcription dna templatedGO:00458932660.011
pigment biosynthetic processGO:0046148360.011
compound eye developmentGO:00487493070.011
regulation of gene expression epigeneticGO:00400291280.011
imaginal disc derived leg morphogenesisGO:0007480800.011
response to oxidative stressGO:0006979860.011
response to hypoxiaGO:0001666530.011
detection of abiotic stimulusGO:0009582660.011
peripheral nervous system developmentGO:0007422520.011
cellular chemical homeostasisGO:0055082400.011
energy taxisGO:0009453210.011
nucleoside phosphate metabolic processGO:00067531620.011
mitotic spindle organizationGO:00070522200.011
anatomical structure homeostasisGO:0060249970.011
rna processingGO:00063961470.011
regulation of i kappab kinase nf kappab signalingGO:004312220.011
neuromuscular synaptic transmissionGO:0007274670.011
response to bacteriumGO:00096171980.010
heart developmentGO:0007507820.010
organic acid catabolic processGO:0016054160.010
imaginal disc pattern formationGO:0007447910.010
regulation of hydrolase activityGO:0051336970.010
cellular response to lipidGO:0071396200.010
response to endogenous stimulusGO:00097191190.010
Zebrafish
cellular component assembly involved in morphogenesisGO:00109271510.010
single organism carbohydrate metabolic processGO:0044723720.010
positive regulation of biosynthetic processGO:00098913160.010
dendrite developmentGO:00163582040.010
regulation of anatomical structure sizeGO:00900661630.010
synaptic target recognitionGO:0008039450.010
lateral inhibitionGO:00463312060.010
epithelial cell differentiationGO:00308553220.010
smoothened signaling pathwayGO:0007224490.010

GRHR disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.043
acquired metabolic diseaseDOID:006015800.043
disease of anatomical entityDOID:700.043
carbohydrate metabolism diseaseDOID:005001300.027
glucose metabolism diseaseDOID:419400.027
lipid metabolism disorderDOID:314600.020
familial hypertriglyceridemiaDOID:005052700.020
inherited metabolic disorderDOID:65500.020
musculoskeletal system diseaseDOID:1700.020
nervous system diseaseDOID:86300.018
type 2 diabetes mellitusDOID:935200.018
diabetes mellitusDOID:935100.018
hypotrichosisDOID:453500.016
integumentary system diseaseDOID:1600.016
hair diseaseDOID:42100.016
amyloidosisDOID:912000.011
familial visceral amyloidosisDOID:005063600.011
connective tissue diseaseDOID:6500.011
bone diseaseDOID:008000100.011