Drosophila melanogaster

0 known processes

Nhe3 (Dmel_CG11328)

Na[+]/H[+] hydrogen exchanger 3

(Aliases: NHE3,nhe3,DmNHE3,CG11328,Dmel\CG11328)

Nhe3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
deathGO:00162652840.283
regulation of response to stressGO:00801342000.233
regulation of response to external stimulusGO:00321011150.227
negative regulation of signalingGO:00230572190.207
endocytosisGO:00068973100.170
intracellular signal transductionGO:00355563000.164
regulation of intracellular signal transductionGO:19025312360.163
response to abiotic stimulusGO:00096283410.159
vesicle mediated transportGO:00161923810.137
defense response to other organismGO:00985422250.135
response to other organismGO:00517072930.132
catabolic processGO:00090564090.132
organic substance catabolic processGO:19015753080.128
cell deathGO:00082192790.121
single organism intracellular transportGO:19025822070.116
defense responseGO:00069523000.116
cellular catabolic processGO:00442483720.110
regulation of phosphate metabolic processGO:00192202100.106
response to radiationGO:00093141550.105
negative regulation of signal transductionGO:00099682060.101
response to biotic stimulusGO:00096072940.101
organophosphate metabolic processGO:00196371950.101
organonitrogen compound metabolic processGO:19015643180.096
organic substance transportGO:00717022570.094
programmed cell deathGO:00125012570.093
establishment of localization in cellGO:00516494020.093
heterocycle catabolic processGO:00467001660.092
single organism behaviorGO:00447083910.089
regulation of localizationGO:00328792750.085
negative regulation of response to stimulusGO:00485852580.080
regulation of transportGO:00510491810.080
meiotic nuclear divisionGO:00071261510.080
apoptotic processGO:00069151590.078
cell divisionGO:00513012480.077
positive regulation of cellular component organizationGO:00511301560.076
response to light stimulusGO:00094161240.076
regulation of cell deathGO:00109411730.076
activation of innate immune responseGO:000221840.076
homeostatic processGO:00425921990.074
Human
lipid metabolic processGO:00066291210.073
protein modification processGO:00362114380.073
regulation of catabolic processGO:00098941700.072
cellular lipid metabolic processGO:0044255830.069
glycosyl compound metabolic processGO:19016571270.068
adult behaviorGO:00305341370.067
pattern recognition receptor signaling pathwayGO:000222120.066
negative regulation of cellular metabolic processGO:00313243820.066
neuron recognitionGO:00080381010.065
regulation of cellular catabolic processGO:00313291570.064
phosphorylationGO:00163102940.063
positive regulation of cell communicationGO:00106472500.063
cellular protein modification processGO:00064644380.063
response to external biotic stimulusGO:00432072930.062
single organism catabolic processGO:00447122280.062
negative regulation of cell communicationGO:00106482230.062
nucleobase containing compound catabolic processGO:00346551650.061
protein localizationGO:00081042840.060
phagocytosisGO:00069092150.059
protein transportGO:00150311550.059
organic cyclic compound catabolic processGO:19013611680.058
regulation of phosphorus metabolic processGO:00511742100.057
mapk cascadeGO:00001651070.056
small molecule metabolic processGO:00442813050.055
innate immune response activating signal transductionGO:000275820.053
meiotic chromosome segregationGO:0045132590.053
cellular nitrogen compound catabolic processGO:00442701650.052
positive regulation of response to stimulusGO:00485843230.051
ribonucleoside triphosphate catabolic processGO:00092031080.050
purine nucleoside metabolic processGO:00422781270.050
aromatic compound catabolic processGO:00194391660.048
single organism carbohydrate metabolic processGO:0044723720.047
glycosyl compound catabolic processGO:19016581120.044
meiotic cell cycle processGO:19030461320.044
cytokinesisGO:0000910900.043
positive regulation of signal transductionGO:00099672230.043
chemical homeostasisGO:0048878920.043
Human
post embryonic appendage morphogenesisGO:00351203850.042
negative regulation of intracellular signal transductionGO:1902532570.042
purine ribonucleoside triphosphate metabolic processGO:00092051190.041
establishment of protein localizationGO:00451841630.040
axon cargo transportGO:0008088290.040
synapse organizationGO:00508081960.040
signal transduction by phosphorylationGO:00230141070.039
nucleobase containing small molecule metabolic processGO:00550861740.039
ribonucleoside catabolic processGO:00424541120.039
carbohydrate derivative metabolic processGO:19011352170.038
purine nucleoside triphosphate metabolic processGO:00091441190.038
organelle localizationGO:00516401480.038
nucleoside triphosphate metabolic processGO:00091411200.038
organonitrogen compound catabolic processGO:19015651280.037
purine ribonucleoside triphosphate catabolic processGO:00092071080.037
ras protein signal transductionGO:0007265880.037
regulation of protein metabolic processGO:00512462560.036
guanosine containing compound metabolic processGO:1901068740.035
regulation of nucleotide catabolic processGO:0030811480.035
organophosphate catabolic processGO:00464341120.035
gtp metabolic processGO:0046039720.035
nucleoside phosphate metabolic processGO:00067531620.035
regulation of i kappab kinase nf kappab signalingGO:004312220.035
nucleotide metabolic processGO:00091171610.034
regulation of cell cycleGO:00517262910.034
regulation of phosphorylationGO:00423251470.034
small gtpase mediated signal transductionGO:0007264880.034
immune response regulating signaling pathwayGO:000276420.034
neurological system processGO:00508773580.034
positive regulation of purine nucleotide metabolic processGO:1900544550.033
regulation of mapk cascadeGO:0043408920.033
eye morphogenesisGO:00485922600.032
nucleoside phosphate catabolic processGO:19012921100.032
positive regulation of transportGO:0051050920.032
intracellular protein transportGO:00068861040.032
intracellular transportGO:00469072280.032
positive regulation of phosphate metabolic processGO:00459371390.032
ribonucleoside triphosphate metabolic processGO:00091991190.031
nucleotide catabolic processGO:00091661090.031
locomotory behaviorGO:00076261760.031
carbohydrate derivative catabolic processGO:19011361180.031
regulation of cellular response to stressGO:0080135890.031
defense response to bacteriumGO:00427421780.031
nuclear importGO:0051170510.031
nucleoside triphosphate catabolic processGO:00091431080.031
regulation of multi organism processGO:00439001310.031
cellular macromolecule localizationGO:00707272200.030
body morphogenesisGO:001017120.030
purine ribonucleotide catabolic processGO:00091541090.030
positive regulation of multicellular organismal processGO:00512401430.030
regulation of synapse structure and activityGO:00508031280.029
nucleoside catabolic processGO:00091641120.029
negative regulation of defense responseGO:0031348350.029
purine nucleotide metabolic processGO:00061631460.029
purine ribonucleoside metabolic processGO:00461281270.029
nuclear divisionGO:00002803320.029
cell motilityGO:00488702510.029
organelle fissionGO:00482853400.029
purine nucleoside catabolic processGO:00061521120.029
multi multicellular organism processGO:00447061230.029
regulation of multicellular organismal developmentGO:20000264140.028
taxisGO:00423303040.028
cellular response to dna damage stimulusGO:00069742230.028
positive regulation of nucleotide metabolic processGO:0045981550.028
embryonic pattern specificationGO:00098801740.028
purine containing compound catabolic processGO:00725231120.028
dendrite developmentGO:00163582040.028
ribose phosphate metabolic processGO:00196931450.027
regulation of catalytic activityGO:00507901850.027
purine ribonucleotide metabolic processGO:00091501450.027
response to bacteriumGO:00096171980.027
positive regulation of signalingGO:00230562430.027
head developmentGO:00603221350.026
ribonucleotide metabolic processGO:00092591450.026
endosomal transportGO:0016197440.026
regulation of intracellular protein transportGO:0033157460.026
positive regulation of macromolecule metabolic processGO:00106044050.026
ribonucleoside metabolic processGO:00091191270.026
guanosine containing compound catabolic processGO:1901069740.026
protein catabolic processGO:00301631010.025
localization of cellGO:00516742570.025
salivary gland developmentGO:00074311620.025
nucleoside metabolic processGO:00091161270.025
regulation of small gtpase mediated signal transductionGO:0051056930.025
regulation of defense responseGO:00313471020.024
negative regulation of nitrogen compound metabolic processGO:00511722650.024
o glycan processingGO:001626630.024
positive regulation of phosphorus metabolic processGO:00105621390.024
purine nucleotide catabolic processGO:00061951090.024
single organism biosynthetic processGO:00447112060.024
immune system processGO:00023763470.024
regulation of response to biotic stimulusGO:0002831630.024
chromosome segregationGO:00070591570.024
cellular macromolecule catabolic processGO:00442651360.024
developmental maturationGO:00217001720.023
regulation of nervous system developmentGO:00519602480.023
positive regulation of catalytic activityGO:00430851180.023
defense response to virusGO:0051607230.023
positive regulation of endopeptidase activityGO:0010950260.023
cell recognitionGO:00080371020.023
ribonucleotide catabolic processGO:00092611090.023
positive regulation of nucleobase containing compound metabolic processGO:00459353320.022
spindle organizationGO:00070512530.022
positive regulation of catabolic processGO:00098961050.022
central nervous system developmentGO:00074172010.022
positive regulation of intracellular signal transductionGO:19025331160.022
spermatid differentiationGO:00485151140.022
multicellular organismal reproductive behaviorGO:00330571100.022
positive regulation of molecular functionGO:00440931360.021
negative regulation of immune system processGO:0002683500.021
purine nucleoside triphosphate catabolic processGO:00091461080.021
glycerolipid metabolic processGO:0046486340.021
organelle assemblyGO:00709251980.021
positive regulation of cellular catabolic processGO:0031331950.021
purine ribonucleoside catabolic processGO:00461301120.021
positive regulation of developmental processGO:00510941430.021
brain developmentGO:00074201200.021
forebrain developmentGO:003090020.021
regulation of ras protein signal transductionGO:0046578930.021
protein targetingGO:0006605640.020
meiotic cell cycleGO:00513211710.020
regulation of protein localizationGO:0032880760.020
regulation of gtp catabolic processGO:0033124440.020
regulation of vesicle mediated transportGO:0060627590.020
negative regulation of cellular biosynthetic processGO:00313272770.020
protein phosphorylationGO:00064681690.019
g protein coupled receptor signaling pathwayGO:00071861360.019
macromolecule catabolic processGO:00090571610.019
secretionGO:00469031090.019
tissue morphogenesisGO:00487292970.019
lipid modificationGO:0030258240.019
generation of precursor metabolites and energyGO:0006091420.019
positive regulation of cell deathGO:0010942690.019
single organism membrane organizationGO:0044802930.018
adult locomotory behaviorGO:0008344760.018
regulation of apoptotic processGO:00429811300.018
molting cycleGO:0042303560.018
regulation of nucleoside metabolic processGO:0009118500.018
compound eye photoreceptor developmentGO:0042051780.018
purine containing compound metabolic processGO:00725211550.018
columnar cuboidal epithelial cell differentiationGO:00020652560.018
positive regulation of programmed cell deathGO:0043068620.018
immune response activating signal transductionGO:000275720.018
regulation of synapse organizationGO:00508071100.018
regulation of anatomical structure sizeGO:00900661630.017
protein ubiquitinationGO:0016567700.017
amine metabolic processGO:0009308120.017
regulation of gtpase activityGO:0043087440.017
positive regulation of nitrogen compound metabolic processGO:00511733540.017
regulation of cellular protein metabolic processGO:00322682430.017
dendrite morphogenesisGO:00488131990.017
regulation of cell sizeGO:0008361630.017
positive regulation of purine nucleotide catabolic processGO:0033123460.017
positive regulation of biosynthetic processGO:00098913160.017
notch signaling pathwayGO:00072191200.017
developmental programmed cell deathGO:00106231380.017
detection of external stimulusGO:0009581660.017
single organism cellular localizationGO:19025801800.016
regulation of ras gtpase activityGO:0032318380.016
positive regulation of nucleic acid templated transcriptionGO:19035082660.016
modification dependent macromolecule catabolic processGO:0043632790.016
regulation of protein transportGO:0051223570.016
regulation of cell divisionGO:0051302720.016
gtp catabolic processGO:0006184720.016
cellular protein localizationGO:00346131600.016
single organism nuclear importGO:1902593510.016
regulation of epithelial cell proliferationGO:005067840.016
positive regulation of immune system processGO:0002684680.016
mitotic cytokinesisGO:0000281500.016
columnar cuboidal epithelial cell developmentGO:00020662490.016
carbohydrate metabolic processGO:0005975820.015
regulation of cell developmentGO:00602842150.015
proteolysis involved in cellular protein catabolic processGO:0051603830.015
regulation of intracellular transportGO:0032386640.015
appendage developmentGO:00487364010.015
regulation of cell differentiationGO:00455953020.015
transmembrane transportGO:00550851390.015
Human
cellular response to chemical stimulusGO:00708871990.015
positive regulation of gtpase activityGO:0043547430.015
cellular amine metabolic processGO:0044106120.015
regulation of establishment of protein localizationGO:0070201610.015
macromolecular complex assemblyGO:00650032560.015
positive regulation of cellular biosynthetic processGO:00313283160.015
regulation of notch signaling pathwayGO:00085931000.015
mitotic spindle organizationGO:00070522200.015
regulation of endocytosisGO:0030100370.015
cell adhesionGO:00071551360.015
protein targeting to nucleusGO:0044744510.014
peptidyl amino acid modificationGO:00181931050.014
carboxylic acid metabolic processGO:0019752920.014
imaginal disc derived appendage morphogenesisGO:00351143950.014
positive regulation of nucleotide catabolic processGO:0030813460.014
appendage morphogenesisGO:00351073970.014
salivary gland histolysisGO:0035070880.014
chemotaxisGO:00069352490.014
transcription from rna polymerase ii promoterGO:00063663680.014
regulation of cellular localizationGO:00603411360.014
embryo development ending in birth or egg hatchingGO:00097921520.014
negative regulation of response to external stimulusGO:0032102220.014
positive regulation of ras gtpase activityGO:0032320360.014
proteolysisGO:00065081920.014
biological adhesionGO:00226101380.013
regulation of purine nucleotide metabolic processGO:1900542620.013
regulation of response to nutrient levelsGO:0032107180.013
digestive tract morphogenesisGO:00485461270.013
regulation of molecular functionGO:00650092170.013
regulation of organelle organizationGO:00330431960.013
positive regulation of apoptotic processGO:0043065470.013
olfactory behaviorGO:0042048970.013
ovarian follicle cell developmentGO:00307072480.013
developmental pigmentationGO:0048066680.013
regulation of cell morphogenesisGO:00226041630.013
modification dependent protein catabolic processGO:0019941780.013
segmentationGO:00352822070.013
organic acid metabolic processGO:00060821030.013
response to organic substanceGO:00100332840.013
microtubule based movementGO:0007018510.013
immune effector processGO:0002252980.013
positive regulation of nucleoside metabolic processGO:0045979470.013
wing disc morphogenesisGO:00074723440.013
dna metabolic processGO:00062592270.012
regulation of lipid transportGO:003236830.012
single fertilizationGO:0007338240.012
ubiquitin dependent protein catabolic processGO:0006511780.012
positive regulation of nervous system developmentGO:0051962690.012
axon guidanceGO:00074112330.012
telencephalon developmentGO:002153720.012
salivary gland cell autophagic cell deathGO:0035071830.012
cation homeostasisGO:0055080510.012
Human
reproductive behaviorGO:00190981220.012
epithelial cell migrationGO:00106311480.012
rho protein signal transductionGO:0007266140.012
innate immune responseGO:00450871440.012
nucleus organizationGO:0006997450.012
regulation of nucleotide metabolic processGO:0006140620.012
morphogenesis of an epitheliumGO:00020092760.012
jnk cascadeGO:0007254500.012
regulation of protein import into nucleusGO:0042306280.012
cytoskeleton dependent intracellular transportGO:0030705440.012
regulation of purine nucleotide catabolic processGO:0033121480.012
regulation of stress activated mapk cascadeGO:0032872410.012
regulation of synaptic transmissionGO:0050804690.012
positive regulation of phosphorylationGO:0042327870.012
regulation of stress activated protein kinase signaling cascadeGO:0070302420.012
circadian rhythmGO:00076231050.012
exocrine system developmentGO:00352721620.011
autophagic cell deathGO:0048102830.011
positive regulation of cell developmentGO:0010720610.011
glycoprotein metabolic processGO:0009100410.011
response to oxygen containing compoundGO:19017002000.011
gland developmentGO:00487321910.011
imaginal disc derived leg morphogenesisGO:0007480800.011
membrane organizationGO:00610241120.011
rhythmic processGO:00485111060.011
secretion by cellGO:00329401010.011
negative regulation of phosphate metabolic processGO:0045936450.011
nucleocytoplasmic transportGO:0006913720.011
detection of light stimulusGO:0009583580.011
cellular protein catabolic processGO:0044257830.011
courtship behaviorGO:0007619680.011
imaginal disc derived wing morphogenesisGO:00074763370.011
regulation of cellular amine metabolic processGO:003323830.011
positive regulation of hydrolase activityGO:0051345780.011
protein import into nucleusGO:0006606510.011
epidermal growth factor receptor signaling pathwayGO:0007173580.011
hindbrain developmentGO:003090220.011
embryonic morphogenesisGO:00485982060.011
eye photoreceptor cell differentiationGO:00017541450.011
negative regulation of nucleobase containing compound metabolic processGO:00459342610.011
intracellular receptor signaling pathwayGO:0030522190.011
mitochondrion distributionGO:0048311100.011
oocyte constructionGO:00073081120.011
positive regulation of neuron apoptotic processGO:004352510.011
regionalizationGO:00030024160.011
regulation of kinase activityGO:0043549530.011
axon developmentGO:00615642970.011
Human
establishment or maintenance of cell polarityGO:00071631670.011
learning or memoryGO:00076111410.010
microtubule based transportGO:0010970420.010
cellularizationGO:0007349900.010
cellular macromolecular complex assemblyGO:00346221530.010
nitrogen compound transportGO:0071705850.010
regulation of erk1 and erk2 cascadeGO:0070372390.010
mesenchymal cell differentiationGO:004876210.010
cellular ketone metabolic processGO:0042180240.010
compound eye developmentGO:00487493070.010
response to lipopolysaccharideGO:003249640.010
positive regulation of cellular component biogenesisGO:0044089800.010
negative regulation of programmed cell deathGO:0043069720.010
regulation of neurogenesisGO:00507671580.010
regulation of erbb signaling pathwayGO:1901184420.010
imaginal disc derived appendage developmentGO:00487373990.010
negative regulation of mapk cascadeGO:0043409230.010
positive regulation of macromolecule biosynthetic processGO:00105572830.010
cognitionGO:00508901410.010
regulation of immune effector processGO:0002697520.010
regulation of cellular amino acid metabolic processGO:000652100.010

Nhe3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.066
nervous system diseaseDOID:86300.029
disease of cellular proliferationDOID:1456600.017
organ system cancerDOID:005068600.017
cancerDOID:16200.017