Drosophila melanogaster

122 known processes

hdc (Dmel_CG15532)

headcase

(Aliases: Dmel\CG15532,Hdc,CG15532,l(3)B4-3-20)

hdc biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
photoreceptor cell differentiationGO:00465301700.889
eye photoreceptor cell differentiationGO:00017541450.832
compound eye photoreceptor cell differentiationGO:00017511400.609
positive regulation of transcription dna templatedGO:00458932660.602
gliogenesisGO:0042063800.580
compound eye photoreceptor developmentGO:0042051780.550
positive regulation of nitrogen compound metabolic processGO:00511733540.503
synaptic transmissionGO:00072682880.419
aggressive behaviorGO:0002118630.366
chromosome organizationGO:00512763600.333
compound eye developmentGO:00487493070.259
protein phosphorylationGO:00064681690.227
regulation of localizationGO:00328792750.212
r7 cell differentiationGO:0045466430.196
regulation of anatomical structure morphogenesisGO:00226032420.183
circadian rhythmGO:00076231050.164
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.159
multi organism behaviorGO:00517051750.152
adult behaviorGO:00305341370.151
photoreceptor cell developmentGO:0042461960.148
multicellular organismal reproductive behaviorGO:00330571100.146
developmental maturationGO:00217001720.146
developmental programmed cell deathGO:00106231380.144
open tracheal system developmentGO:00074242040.142
regulation of transportGO:00510491810.134
glial cell migrationGO:0008347310.133
exocrine system developmentGO:00352721620.132
neuron recognitionGO:00080381010.129
regulation of behaviorGO:0050795750.127
eye photoreceptor cell developmentGO:0042462810.126
axon developmentGO:00615642970.120
regulation of neurogenesisGO:00507671580.117
eye photoreceptor cell fate commitmentGO:0042706370.116
regulation of neuron differentiationGO:00456641030.116
regulation of cell developmentGO:00602842150.115
mating behaviorGO:00076171060.112
regulation of cellular localizationGO:00603411360.106
regulation of oocyte developmentGO:0060281270.104
oxoacid metabolic processGO:00434361030.100
positive regulation of macromolecule metabolic processGO:00106044050.100
protein catabolic processGO:00301631010.089
tissue deathGO:00162711020.088
amine metabolic processGO:0009308120.085
single organism intracellular transportGO:19025822070.084
response to endogenous stimulusGO:00097191190.083
compound eye photoreceptor fate commitmentGO:0001752360.079
catabolic processGO:00090564090.075
tube morphogenesisGO:00352391910.073
regulation of protein metabolic processGO:00512462560.072
photoreceptor cell fate commitmentGO:0046552410.070
regulation of r7 cell differentiationGO:0045676150.070
appendage developmentGO:00487364010.069
maintenance of locationGO:0051235730.066
cellular protein modification processGO:00064644380.065
tube developmentGO:00352952440.061
cytoplasmic transportGO:00164821300.060
oocyte maturationGO:000155630.059
positive regulation of macromolecule biosynthetic processGO:00105572830.059
positive regulation of rna biosynthetic processGO:19026802660.058
compound eye cone cell differentiationGO:0042675130.057
response to nutrient levelsGO:00316671140.057
sex differentiationGO:0007548810.056
regulation of cellular amino acid metabolic processGO:000652100.056
cellular amine metabolic processGO:0044106120.052
cellular response to dna damage stimulusGO:00069742230.050
taxisGO:00423303040.050
positive regulation of nucleic acid templated transcriptionGO:19035082660.050
transcription from rna polymerase ii promoterGO:00063663680.050
pole plasm mrna localizationGO:0019094490.048
neuron fate commitmentGO:0048663500.048
positive regulation of cellular biosynthetic processGO:00313283160.048
imaginal disc derived appendage morphogenesisGO:00351143950.048
inter male aggressive behaviorGO:0002121600.047
phosphorylationGO:00163102940.046
intercellular transportGO:001049620.045
learning or memoryGO:00076111410.043
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.042
eye developmentGO:00016543230.040
synapse assemblyGO:00074161430.040
localization of cellGO:00516742570.040
positive regulation of cell communicationGO:00106472500.040
detection of stimulusGO:00516061560.039
eye morphogenesisGO:00485922600.038
central nervous system developmentGO:00074172010.037
autophagic cell deathGO:0048102830.037
regulation of synaptic transmissionGO:0050804690.037
regulation of cellular amine metabolic processGO:003323830.036
lateral inhibitionGO:00463312060.036
r7 cell fate commitmentGO:0007465120.036
olfactory behaviorGO:0042048970.036
regulation of multicellular organismal developmentGO:20000264140.035
negative regulation of signalingGO:00230572190.035
regulation of establishment of protein localizationGO:0070201610.035
response to radiationGO:00093141550.035
cell motilityGO:00488702510.035
salivary gland histolysisGO:0035070880.034
mitotic cytokinesisGO:0000281500.033
negative regulation of cellular protein metabolic processGO:0032269850.033
positive regulation of r7 cell differentiationGO:004567870.031
response to light stimulusGO:00094161240.030
positive regulation of synaptic transmissionGO:0050806150.030
regulation of membrane potentialGO:0042391350.030
phenol containing compound metabolic processGO:0018958570.030
response to abiotic stimulusGO:00096283410.030
compound eye cone cell fate commitmentGO:004267650.029
positive regulation of protein metabolic processGO:00512471280.029
regulation of embryonic developmentGO:0045995680.029
negative regulation of cell differentiationGO:00455961430.028
regulation of phosphorus metabolic processGO:00511742100.028
chemosensory behaviorGO:00076351060.028
response to other organismGO:00517072930.027
imaginal disc derived appendage developmentGO:00487373990.027
positive regulation of nucleobase containing compound metabolic processGO:00459353320.027
negative regulation of response to stimulusGO:00485852580.027
g protein coupled receptor signaling pathwayGO:00071861360.027
gland developmentGO:00487321910.027
cell junction organizationGO:0034330570.026
regulation of reproductive processGO:2000241540.026
detection of external stimulusGO:0009581660.025
negative regulation of molecular functionGO:0044092510.025
deathGO:00162652840.025
agingGO:00075681430.024
salivary gland cell autophagic cell deathGO:0035071830.024
cell proliferationGO:00082832990.024
organic substance catabolic processGO:19015753080.023
protein import into nucleusGO:0006606510.023
regulation of photoreceptor cell differentiationGO:0046532340.022
associative learningGO:0008306650.022
cognitionGO:00508901410.022
reproductive behaviorGO:00190981220.022
cellular component assembly involved in morphogenesisGO:00109271510.021
cell agingGO:000756920.021
oocyte anterior posterior axis specificationGO:0007314720.021
chromatin organizationGO:00063252070.021
salivary gland developmentGO:00074311620.021
muscle structure developmentGO:00610612240.021
negative regulation of signal transductionGO:00099682060.020
courtship behaviorGO:0007619680.020
telencephalon developmentGO:002153720.020
positive regulation of gene expressionGO:00106282900.020
protein localizationGO:00081042840.020
neuron neuron synaptic transmissionGO:0007270140.019
macromolecule catabolic processGO:00090571610.019
organic substance transportGO:00717022570.019
multi multicellular organism processGO:00447061230.019
regulation of phosphorylationGO:00423251470.019
cellular response to endogenous stimulusGO:0071495800.018
covalent chromatin modificationGO:00165691060.018
male mating behaviorGO:0060179700.018
regulation of response to stressGO:00801342000.017
retina development in camera type eyeGO:006004140.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.017
cell divisionGO:00513012480.017
negative regulation of phosphorylationGO:0042326350.017
lipid storageGO:0019915380.017
growthGO:00400073590.017
neurological system processGO:00508773580.017
protein importGO:0017038550.017
axis specificationGO:00097981670.017
multi organism reproductive behaviorGO:00447051210.017
regulation of anatomical structure sizeGO:00900661630.017
endomembrane system organizationGO:00102561190.017
oocyte differentiationGO:00099941450.017
protein modification processGO:00362114380.016
release of sequestered calcium ion into cytosolGO:005120910.016
positive regulation of biosynthetic processGO:00098913160.016
intracellular signal transductionGO:00355563000.016
carboxylic acid metabolic processGO:0019752920.016
regulation of nervous system developmentGO:00519602480.016
positive regulation of intracellular signal transductionGO:19025331160.016
negative regulation of cellular metabolic processGO:00313243820.016
striated muscle cell differentiationGO:0051146900.016
delaminationGO:006023280.016
cellular macromolecule localizationGO:00707272200.016
chromatin modificationGO:00165681470.015
peptidyl amino acid modificationGO:00181931050.015
cell maturationGO:00484691440.015
programmed cell deathGO:00125012570.015
proteolysis involved in cellular protein catabolic processGO:0051603830.015
notch signaling pathwayGO:00072191200.015
negative regulation of cell developmentGO:0010721620.015
regulation of compound eye cone cell fate specificationGO:004268240.015
locomotory behaviorGO:00076261760.015
circadian behaviorGO:0048512760.015
cranial nerve developmentGO:002154510.014
regulation of protein modification processGO:00313991120.014
histolysisGO:00075591020.014
single organism behaviorGO:00447083910.014
regulation of cellular component biogenesisGO:00440872010.014
forebrain developmentGO:003090020.014
optic placode formationGO:000174340.014
regulation of cell morphogenesis involved in differentiationGO:0010769610.014
compound eye retinal cell programmed cell deathGO:0046667230.014
cellular amino acid metabolic processGO:0006520610.014
larval developmentGO:00021641040.014
establishment of localization in cellGO:00516494020.013
response to oxygen containing compoundGO:19017002000.013
establishment of protein localization to plasma membraneGO:009000290.013
nucleus localizationGO:0051647340.013
adult locomotory behaviorGO:0008344760.013
autophagyGO:00069141080.013
regulation of protein localization to plasma membraneGO:190307670.013
response to hormoneGO:0009725450.013
regulation of cell cell adhesionGO:0022407210.013
neuromuscular synaptic transmissionGO:0007274670.013
neuron fate specificationGO:0048665120.013
nitrogen compound transportGO:0071705850.013
cell cell signaling involved in cell fate commitmentGO:00451682100.013
negative regulation of cell communicationGO:00106482230.013
proteolysisGO:00065081920.013
single organism cellular localizationGO:19025801800.013
positive regulation of neurotransmitter transportGO:005159020.013
embryonic morphogenesisGO:00485982060.013
regulation of protein localizationGO:0032880760.012
dorsal ventral axis specificationGO:0009950660.012
cell junction assemblyGO:0034329420.012
compound eye morphogenesisGO:00017452490.012
female germ line cyst formationGO:0048135420.012
brain developmentGO:00074201200.012
regulation of erbb signaling pathwayGO:1901184420.012
regulation of mapk cascadeGO:0043408920.012
germ line cyst formationGO:0048134440.012
regulation of transcription from rna polymerase ii promoterGO:00063573780.012
camera type eye morphogenesisGO:004859320.012
ecdysone mediated induction of salivary gland cell autophagic cell deathGO:0035072120.012
regulation of striated muscle contractionGO:000694220.012
peripheral nervous system developmentGO:0007422520.012
regulation of transferase activityGO:0051338580.012
phagocytosisGO:00069092150.012
establishment of protein localization to organelleGO:0072594620.012
dopamine biosynthetic processGO:004241630.012
regulation of circadian rhythmGO:0042752490.012
chemotaxisGO:00069352490.012
cellular protein catabolic processGO:0044257830.011
response to ketoneGO:1901654340.011
cell cycle checkpointGO:0000075950.011
response to alcoholGO:0097305950.011
positive regulation of bindingGO:005109940.011
hematopoietic or lymphoid organ developmentGO:0048534570.011
olfactory learningGO:0008355560.011
translationGO:0006412690.011
positive regulation of phosphorylationGO:0042327870.011
mesodermal cell fate specificationGO:000750120.011
eye antennal disc developmentGO:0035214600.011
detection of abiotic stimulusGO:0009582660.011
regulation of phosphate metabolic processGO:00192202100.011
photoreceptor cell fate specificationGO:004370490.011
glial cell differentiationGO:0010001350.011
regulation of molecular functionGO:00650092170.011
cellular response to biotic stimulusGO:007121640.010
negative regulation of protein metabolic processGO:0051248850.010
epithelial cell developmentGO:00020642740.010
regulation of cellular protein metabolic processGO:00322682430.010

hdc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nonsyndromic deafnessDOID:005056300.014
autosomal dominant nonsyndromic deafnessDOID:005056400.014
auditory system diseaseDOID:274200.014
nervous system diseaseDOID:86300.014
disease of anatomical entityDOID:700.014
sensory system diseaseDOID:005015500.014