Drosophila melanogaster

57 known processes

shf (Dmel_CG3135)

shifted

(Aliases: Dmel\CG3135,CG3135,CG3134,DmWif,CT10514,Shf,shf-ov,D-Wif,DmWIF)

shf biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
wing disc morphogenesisGO:00074723440.324
embryonic morphogenesisGO:00485982060.203
male sex differentiationGO:0046661250.201
imaginal disc derived wing morphogenesisGO:00074763370.200
imaginal disc derived appendage developmentGO:00487373990.181
negative regulation of nucleic acid templated transcriptionGO:19035072400.162
single organism biosynthetic processGO:00447112060.161
regulation of immune system processGO:00026821760.158
negative regulation of cell communicationGO:00106482230.157
Zebrafish
leg disc developmentGO:0035218920.152
appendage morphogenesisGO:00351073970.142
tissue morphogenesisGO:00487292970.139
brain developmentGO:00074201200.133
torso signaling pathwayGO:0008293210.132
circadian rhythmGO:00076231050.130
negative regulation of signal transductionGO:00099682060.130
Zebrafish
positive regulation of signalingGO:00230562430.129
morphogenesis of an epitheliumGO:00020092760.117
imaginal disc derived appendage morphogenesisGO:00351143950.111
imaginal disc derived wing vein specificationGO:0007474480.100
camera type eye developmentGO:004301040.097
cellular component assembly involved in morphogenesisGO:00109271510.090
kidney epithelium developmentGO:007207330.088
terminal region determinationGO:0007362250.088
kidney developmentGO:000182230.087
memoryGO:0007613940.087
post embryonic appendage morphogenesisGO:00351203850.086
regulation of multicellular organismal developmentGO:20000264140.085
negative regulation of macromolecule biosynthetic processGO:00105582700.085
positive regulation of cell communicationGO:00106472500.083
regulation of multicellular organism growthGO:0040014400.081
learning or memoryGO:00076111410.078
appendage developmentGO:00487364010.076
lipid metabolic processGO:00066291210.072
embryonic pattern specificationGO:00098801740.071
negative regulation of hormone biosynthetic processGO:003235310.070
connective tissue developmentGO:006144830.066
tube morphogenesisGO:00352391910.066
sensory organ morphogenesisGO:00905962600.066
pigmentationGO:0043473750.065
regulation of behaviorGO:0050795750.065
circadian behaviorGO:0048512760.064
regionalizationGO:00030024160.064
pigment biosynthetic processGO:0046148360.063
axis specificationGO:00097981670.063
cognitionGO:00508901410.062
amine metabolic processGO:0009308120.060
cellular response to oxygen containing compoundGO:1901701790.059
positive regulation of multicellular organismal processGO:00512401430.059
protein phosphorylationGO:00064681690.059
protein modification processGO:00362114380.058
dorsal closureGO:0007391790.057
epithelial cell differentiationGO:00308553220.057
negative regulation of developmental processGO:00510932010.056
developmental pigmentationGO:0048066680.056
embryonic development via the syncytial blastodermGO:00017001480.055
segmentationGO:00352822070.055
negative regulation of response to stimulusGO:00485852580.055
Zebrafish
regulation of protein metabolic processGO:00512462560.053
negative regulation of signalingGO:00230572190.053
Zebrafish
regulation of cell differentiationGO:00455953020.052
Mouse
negative regulation of biosynthetic processGO:00098902770.052
tube developmentGO:00352952440.052
cellular protein modification processGO:00064644380.052
establishment of localization in cellGO:00516494020.051
extracellular structure organizationGO:0043062460.049
developmental growthGO:00485892800.049
regulation of cellular ketone metabolic processGO:001056530.047
positive regulation of developmental growthGO:0048639620.047
negative regulation of nitrogen compound metabolic processGO:00511722650.046
negative regulation of rna biosynthetic processGO:19026792400.046
leg disc morphogenesisGO:0007478800.045
camera type eye morphogenesisGO:004859320.045
regulation of cellular localizationGO:00603411360.045
immune system processGO:00023763470.044
male gonad developmentGO:000858490.043
negative regulation of nucleobase containing compound metabolic processGO:00459342610.043
cellular ketone metabolic processGO:0042180240.043
response to lipopolysaccharideGO:003249640.042
negative regulation of cell differentiationGO:00455961430.042
organic substance transportGO:00717022570.041
intracellular signal transductionGO:00355563000.041
growthGO:00400073590.040
rhythmic behaviorGO:0007622760.040
transmembrane transportGO:00550851390.040
sensory perception of painGO:001923340.039
imaginal disc derived leg morphogenesisGO:0007480800.039
regulation of transcription from rna polymerase ii promoterGO:00063573780.039
protein targetingGO:0006605640.038
regulation of localizationGO:00328792750.038
zygotic determination of anterior posterior axis embryoGO:0007354270.038
negative regulation of nervous system developmentGO:0051961920.038
developmental maturationGO:00217001720.037
homeostatic processGO:00425921990.037
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.036
single organism carbohydrate metabolic processGO:0044723720.036
nephron developmentGO:007200630.036
blastoderm segmentationGO:00073501590.034
extracellular matrix organizationGO:0030198320.034
response to monosaccharideGO:003428440.034
deathGO:00162652840.034
anterior posterior pattern specificationGO:00099521360.034
protein complex biogenesisGO:00702712010.034
nephron epithelium developmentGO:007200930.033
oocyte dorsal ventral axis specificationGO:0007310340.033
rhythmic processGO:00485111060.033
regulation of developmental growthGO:00486381740.033
positive regulation of growthGO:0045927750.032
protein complex assemblyGO:00064612000.032
enzyme linked receptor protein signaling pathwayGO:00071671790.032
neurological system processGO:00508773580.032
anatomical structure homeostasisGO:0060249970.031
cellular response to organic substanceGO:00713101320.031
regulation of intracellular signal transductionGO:19025312360.031
negative regulation of gene expressionGO:00106293870.030
actin cytoskeleton organizationGO:00300362060.030
negative regulation of cellular biosynthetic processGO:00313272770.030
lipid modificationGO:0030258240.030
oocyte developmentGO:00485991240.030
regulation of molecular functionGO:00650092170.030
response to oxidative stressGO:0006979860.029
actin filament based processGO:00300292200.029
eggshell chorion assemblyGO:0007306660.029
macromolecular complex assemblyGO:00650032560.029
secretionGO:00469031090.029
response to organic substanceGO:00100332840.028
regulation of neuron differentiationGO:00456641030.028
multicellular organism growthGO:0035264460.028
regulation of growthGO:00400082330.028
regulation of neurogenesisGO:00507671580.028
positive regulation of multicellular organism growthGO:0040018210.028
transcription from rna polymerase ii promoterGO:00063663680.027
negative regulation of rna metabolic processGO:00512532510.027
positive regulation of developmental processGO:00510941430.027
Mouse
organonitrogen compound metabolic processGO:19015643180.026
salivary gland developmentGO:00074311620.026
positive regulation of signal transductionGO:00099672230.026
body morphogenesisGO:001017120.025
multicellular organismal homeostasisGO:0048871410.025
immune system developmentGO:0002520570.025
response to oxygen containing compoundGO:19017002000.025
synaptic transmissionGO:00072682880.025
vesicle mediated transportGO:00161923810.025
stem cell developmentGO:0048864790.025
adult behaviorGO:00305341370.025
defense responseGO:00069523000.024
nephron morphogenesisGO:007202830.024
positive regulation of cellular amine metabolic processGO:003324000.024
negative regulation of multicellular organismal processGO:00512411420.024
regulation of secretion by cellGO:1903530390.024
reproductive system developmentGO:0061458740.023
carbohydrate metabolic processGO:0005975820.023
single organism behaviorGO:00447083910.023
molting cycleGO:0042303560.023
regulation of transportGO:00510491810.023
skin developmentGO:0043588650.022
immune responseGO:00069552460.022
molting cycle chitin based cuticleGO:0007591560.022
central nervous system developmentGO:00074172010.021
ovarian follicle cell developmentGO:00307072480.021
response to external biotic stimulusGO:00432072930.021
phagocytosisGO:00069092150.021
response to abiotic stimulusGO:00096283410.021
regulation of cell cycleGO:00517262910.021
positive regulation of cellular component organizationGO:00511301560.021
positive regulation of nervous system developmentGO:0051962690.020
anterior posterior axis specificationGO:00099481090.020
chemical homeostasisGO:0048878920.020
negative regulation of transcription dna templatedGO:00458922370.020
response to other organismGO:00517072930.020
digestive system developmentGO:00551231490.020
negative regulation of cellular metabolic processGO:00313243820.020
organic acid metabolic processGO:00060821030.020
positive regulation of response to stimulusGO:00485843230.020
positive regulation of cellular amino acid metabolic processGO:004576400.019
non sensory hair organizationGO:0035316470.019
chaeta morphogenesisGO:0008407420.019
cellular response to dna damage stimulusGO:00069742230.019
anterior posterior axis specification embryoGO:00085951030.019
eye morphogenesisGO:00485922600.019
establishment of planar polarityGO:0001736870.019
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.019
cellular response to hexose stimulusGO:007133110.019
cellular macromolecule localizationGO:00707272200.019
cellular response to chemical stimulusGO:00708871990.018
catabolic processGO:00090564090.018
protein targeting to nucleusGO:0044744510.018
ion transmembrane transportGO:00342201220.018
oxoacid metabolic processGO:00434361030.018
regulation of immune responseGO:00507761180.018
response to ketoneGO:1901654340.018
dorsal appendage formationGO:0046843470.018
cell maturationGO:00484691440.018
chromatin organizationGO:00063252070.018
myotube cell developmentGO:001490430.018
small molecule metabolic processGO:00442813050.018
multi organism behaviorGO:00517051750.018
development of primary male sexual characteristicsGO:004654690.018
positive regulation of cellular catabolic processGO:0031331950.018
cellular amino acid metabolic processGO:0006520610.017
response to glucoseGO:000974920.017
cellular amine metabolic processGO:0044106120.017
columnar cuboidal epithelial cell differentiationGO:00020652560.017
protein localization to organelleGO:0033365820.017
erk1 and erk2 cascadeGO:0070371390.017
cell adhesionGO:00071551360.017
negative regulation of cellular protein metabolic processGO:0032269850.017
cell deathGO:00082192790.017
positive regulation of transcription dna templatedGO:00458932660.017
actin filament organizationGO:00070151260.017
synapse organizationGO:00508081960.017
forebrain developmentGO:003090020.017
hemopoiesisGO:0030097460.016
response to endogenous stimulusGO:00097191190.016
intracellular transportGO:00469072280.016
positive regulation of catabolic processGO:00098961050.016
negative regulation of molecular functionGO:0044092510.016
gland morphogenesisGO:00226121450.016
tripartite regional subdivisionGO:00073511030.016
negative regulation of cell cycleGO:00457861160.016
regulation of bmp signaling pathwayGO:0030510230.016
muscle attachmentGO:0016203360.016
chorion containing eggshell formationGO:00073041050.015
sensory perceptionGO:00076001960.015
developmental programmed cell deathGO:00106231380.015
kidney morphogenesisGO:006099330.015
neuromuscular junction developmentGO:00075281490.015
response to organic cyclic compoundGO:0014070890.015
reproductive structure developmentGO:0048608740.015
positive regulation of defense responseGO:0031349590.015
response to light stimulusGO:00094161240.015
nephron tubule developmentGO:007208030.015
epithelial cell developmentGO:00020642740.015
regulation of cellular amine metabolic processGO:003323830.015
morphogenesis of embryonic epitheliumGO:0016331940.015
regulation of ras protein signal transductionGO:0046578930.015
eye developmentGO:00016543230.015
monocarboxylic acid transportGO:001571830.015
columnar cuboidal epithelial cell developmentGO:00020662490.015
single organism nuclear importGO:1902593510.015
digestive tract morphogenesisGO:00485461270.015
eggshell formationGO:00307031050.015
muscle cell differentiationGO:00426921030.014
response to nitrogen compoundGO:1901698900.014
response to alcoholGO:0097305950.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.014
negative regulation of peptide hormone secretionGO:009027810.014
dorsal ventral axis specificationGO:0009950660.014
positive regulation of cell migrationGO:003033520.014
locomotor rhythmGO:0045475560.014
gastrulationGO:0007369700.014
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.014
positive regulation of nucleic acid templated transcriptionGO:19035082660.014
dorsal ventral pattern formationGO:00099531330.014
single organism cellular localizationGO:19025801800.014
extrinsic apoptotic signaling pathwayGO:009719110.014
response to bacteriumGO:00096171980.014
synapse assemblyGO:00074161430.014
synaptic growth at neuromuscular junctionGO:00511241190.014
morphogenesis of a polarized epitheliumGO:0001738930.014
collateral sproutingGO:004866830.014
regulation of locomotionGO:0040012420.014
secretion by cellGO:00329401010.014
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.014
endocytosisGO:00068973100.013
regulation of notch signaling pathwayGO:00085931000.013
gland developmentGO:00487321910.013
nuclear importGO:0051170510.013
locomotory behaviorGO:00076261760.013
protein transportGO:00150311550.013
intracellular protein transportGO:00068861040.013
negative regulation of cell developmentGO:0010721620.013
protein localizationGO:00081042840.013
pigment metabolic processGO:0042440840.013
regulation of intracellular transportGO:0032386640.013
biological adhesionGO:00226101380.013
cellular nitrogen compound catabolic processGO:00442701650.013
cuticle developmentGO:0042335860.012
positive regulation of cell motilityGO:200014730.012
positive regulation of neuron apoptotic processGO:004352510.012
single organism intracellular transportGO:19025822070.012
cellular protein localizationGO:00346131600.012
cell motilityGO:00488702510.012
development of primary sexual characteristicsGO:0045137500.012
glandular epithelial cell differentiationGO:000206710.012
positive regulation of synapse assemblyGO:0051965290.012
ion transportGO:00068111450.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.012
response to hexoseGO:000974630.012
carboxylic acid metabolic processGO:0019752920.012
establishment of protein localizationGO:00451841630.012
adult feeding behaviorGO:0008343130.012
single organism catabolic processGO:00447122280.012
regulation of synapse organizationGO:00508071100.012
regulation of establishment of protein localizationGO:0070201610.012
imaginal disc derived wing hair organizationGO:0035317450.012
skeletal muscle organ developmentGO:0060538480.012
somatic muscle developmentGO:0007525660.012
regulation of cell cycle processGO:00105641810.012
reproductive behaviorGO:00190981220.012
imaginal disc derived leg segmentationGO:0036011260.011
positive regulation of cellular biosynthetic processGO:00313283160.011
multicellular organismal reproductive behaviorGO:00330571100.011
head developmentGO:00603221350.011
regulation of nervous system developmentGO:00519602480.011
cellular protein complex assemblyGO:0043623710.011
male gamete generationGO:00482322010.011
positive regulation of gene expressionGO:00106282900.011
respiratory system developmentGO:00605412130.011
regulation of lipid transportGO:003236830.011
regulation of anatomical structure sizeGO:00900661630.011
regulation of intracellular protein transportGO:0033157460.011
exocrine system developmentGO:00352721620.011
regulation of mrna splicing via spliceosomeGO:0048024640.011
embryonic hemopoiesisGO:0035162260.011
regulation of membrane potentialGO:0042391350.011
wnt signaling pathwayGO:0016055980.011
cellular catabolic processGO:00442483720.011
cellular response to monosaccharide stimulusGO:007132620.011
regulation of cellular component movementGO:0051270420.011
musculoskeletal movementGO:005088130.011
cellular macromolecular complex assemblyGO:00346221530.011
nucleoside phosphate catabolic processGO:19012921100.011
molting cycle processGO:0022404290.010
response to woundingGO:0009611940.010
axon guidanceGO:00074112330.010
digestive tract developmentGO:00485651490.010
organic hydroxy compound biosynthetic processGO:1901617210.010
cellular amide metabolic processGO:0043603800.010
apoptotic process involved in morphogenesisGO:006056130.010
regulation of cell developmentGO:00602842150.010
negative regulation of calcium ion importGO:009028120.010
anion transportGO:0006820410.010
apoptotic processGO:00069151590.010
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.010
establishment of protein localization to organelleGO:0072594620.010
nucleobase containing compound transportGO:0015931560.010
positive regulation of protein metabolic processGO:00512471280.010

shf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.047
disease of anatomical entityDOID:700.045
nervous system diseaseDOID:86300.045
cancerDOID:16200.035
organ system cancerDOID:005068600.035
disease of metabolismDOID:001466700.023
inherited metabolic disorderDOID:65500.023
cardiovascular system diseaseDOID:128700.018
sensory system diseaseDOID:005015500.012
eye diseaseDOID:561400.011
eye and adnexa diseaseDOID:149200.011
central nervous system diseaseDOID:33100.011
urinary system diseaseDOID:1800.011