Drosophila melanogaster

49 known processes

LKR (Dmel_CG7144)

lysine ketoglutarate reductase

(Aliases: CG7144,dLKR,BEST:CK02318,Dmel\CG7144,CK02318,SDH,anon-WO0149856.1)

LKR biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
g protein coupled receptor signaling pathwayGO:00071861360.125
response to organic substanceGO:00100332840.095
organic substance transportGO:00717022570.065
negative regulation of gene expressionGO:00106293870.056
negative regulation of nucleobase containing compound metabolic processGO:00459342610.053
cellular protein modification processGO:00064644380.051
transmembrane transportGO:00550851390.050
negative regulation of cellular metabolic processGO:00313243820.049
embryonic development via the syncytial blastodermGO:00017001480.049
regionalizationGO:00030024160.047
response to abiotic stimulusGO:00096283410.045
negative regulation of nitrogen compound metabolic processGO:00511722650.042
immune system processGO:00023763470.040
single organism behaviorGO:00447083910.040
regulation of transcription from rna polymerase ii promoterGO:00063573780.040
single organism biosynthetic processGO:00447112060.039
negative regulation of biosynthetic processGO:00098902770.037
organonitrogen compound metabolic processGO:19015643180.037
dorsal ventral pattern formationGO:00099531330.036
l amino acid importGO:004309220.036
adult behaviorGO:00305341370.036
negative regulation of cellular biosynthetic processGO:00313272770.035
small molecule metabolic processGO:00442813050.034
epithelial cell differentiationGO:00308553220.034
transcription from rna polymerase ii promoterGO:00063663680.033
forebrain developmentGO:003090020.032
negative regulation of rna metabolic processGO:00512532510.032
immune responseGO:00069552460.032
response to oxygen containing compoundGO:19017002000.032
imaginal disc derived appendage morphogenesisGO:00351143950.032
organelle fissionGO:00482853400.032
wing disc morphogenesisGO:00074723440.031
multicellular organismal reproductive behaviorGO:00330571100.031
appendage developmentGO:00487364010.029
protein modification processGO:00362114380.029
multi organism reproductive behaviorGO:00447051210.029
matingGO:00076181200.028
ion transmembrane transportGO:00342201220.028
nitrogen compound transportGO:0071705850.027
reproductive behaviorGO:00190981220.027
establishment of localization in cellGO:00516494020.027
response to organic cyclic compoundGO:0014070890.027
embryo development ending in birth or egg hatchingGO:00097921520.026
localization of cellGO:00516742570.026
cell deathGO:00082192790.026
ion transportGO:00068111450.026
macromolecular complex assemblyGO:00650032560.026
appendage morphogenesisGO:00351073970.026
positive regulation of response to stimulusGO:00485843230.026
vesicle mediated transportGO:00161923810.026
regulation of cell deathGO:00109411730.025
multi organism behaviorGO:00517051750.025
compound eye developmentGO:00487493070.025
regulation of protein metabolic processGO:00512462560.025
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.025
chromosome organizationGO:00512763600.025
cellular amino acid metabolic processGO:0006520610.025
imaginal disc derived appendage developmentGO:00487373990.024
nucleoside phosphate metabolic processGO:00067531620.024
cell cell signaling involved in cell fate commitmentGO:00451682100.024
imaginal disc derived wing morphogenesisGO:00074763370.024
neuropeptide signaling pathwayGO:0007218450.024
protein complex biogenesisGO:00702712010.024
cell motilityGO:00488702510.024
developmental growthGO:00485892800.023
innate immune responseGO:00450871440.023
negative regulation of nucleic acid templated transcriptionGO:19035072400.023
negative regulation of transcription dna templatedGO:00458922370.023
oxoacid metabolic processGO:00434361030.023
post embryonic appendage morphogenesisGO:00351203850.023
intracellular transportGO:00469072280.023
regulation of intracellular signal transductionGO:19025312360.023
positive regulation of signalingGO:00230562430.023
nuclear divisionGO:00002803320.023
negative regulation of macromolecule biosynthetic processGO:00105582700.023
positive regulation of macromolecule metabolic processGO:00106044050.023
deathGO:00162652840.022
endocytosisGO:00068973100.022
meiotic nuclear divisionGO:00071261510.022
negative regulation of rna biosynthetic processGO:19026792400.022
central nervous system developmentGO:00074172010.022
positive regulation of biosynthetic processGO:00098913160.021
phosphorylationGO:00163102940.021
growthGO:00400073590.021
regulation of anatomical structure morphogenesisGO:00226032420.021
phagocytosisGO:00069092150.021
positive regulation of cell communicationGO:00106472500.021
imaginal disc pattern formationGO:0007447910.021
regulation of cellular protein metabolic processGO:00322682430.021
cell migrationGO:00164772380.020
positive regulation of cellular biosynthetic processGO:00313283160.020
wing disc pattern formationGO:0035222660.020
response to radiationGO:00093141550.020
intracellular signal transductionGO:00355563000.020
eye developmentGO:00016543230.020
regulation of localizationGO:00328792750.020
organophosphate metabolic processGO:00196371950.019
morphogenesis of an epitheliumGO:00020092760.019
protein localizationGO:00081042840.019
negative regulation of multicellular organismal processGO:00512411420.019
positive regulation of transcription dna templatedGO:00458932660.019
epithelial cell developmentGO:00020642740.019
lateral inhibitionGO:00463312060.019
regulation of programmed cell deathGO:00430671520.019
cellular response to dna damage stimulusGO:00069742230.019
protein complex assemblyGO:00064612000.018
programmed cell deathGO:00125012570.018
positive regulation of nitrogen compound metabolic processGO:00511733540.018
multi multicellular organism processGO:00447061230.018
defense responseGO:00069523000.018
positive regulation of signal transductionGO:00099672230.018
response to light stimulusGO:00094161240.018
single organism intracellular transportGO:19025822070.018
body morphogenesisGO:001017120.018
mating behaviorGO:00076171060.018
nucleobase containing small molecule metabolic processGO:00550861740.018
catabolic processGO:00090564090.018
chaeta developmentGO:0022416970.018
positive regulation of nucleic acid templated transcriptionGO:19035082660.018
nucleotide metabolic processGO:00091171610.018
male mating behaviorGO:0060179700.018
positive regulation of rna biosynthetic processGO:19026802660.018
locomotory behaviorGO:00076261760.017
positive regulation of gene expressionGO:00106282900.017
regulation of response to stressGO:00801342000.017
compound eye morphogenesisGO:00017452490.017
regulation of phosphorus metabolic processGO:00511742100.017
columnar cuboidal epithelial cell differentiationGO:00020652560.017
response to endogenous stimulusGO:00097191190.016
cellular response to chemical stimulusGO:00708871990.016
organonitrogen compound biosynthetic processGO:19015661170.016
male gamete generationGO:00482322010.016
negative regulation of signalingGO:00230572190.016
amine metabolic processGO:0009308120.016
positive regulation of macromolecule biosynthetic processGO:00105572830.016
homeostatic processGO:00425921990.016
cellular response to organic substanceGO:00713101320.016
gland developmentGO:00487321910.016
positive regulation of rna metabolic processGO:00512542710.016
regulation of cell cycleGO:00517262910.016
ameboidal type cell migrationGO:00016671510.016
salivary gland morphogenesisGO:00074351450.016
meiotic cell cycleGO:00513211710.016
determination of adult lifespanGO:00083401370.016
cell growthGO:00160491080.015
regulation of apoptotic processGO:00429811300.015
protein phosphorylationGO:00064681690.015
carboxylic acid metabolic processGO:0019752920.015
response to nitrogen compoundGO:1901698900.015
spermatogenesisGO:00072832000.015
positive regulation of intracellular signal transductionGO:19025331160.015
brain developmentGO:00074201200.015
ovarian follicle cell developmentGO:00307072480.015
positive regulation of nucleobase containing compound metabolic processGO:00459353320.015
regulation of cellular component sizeGO:0032535980.014
muscle structure developmentGO:00610612240.014
response to monosaccharideGO:003428440.014
spindle organizationGO:00070512530.014
carbohydrate metabolic processGO:0005975820.014
humoral immune responseGO:00069591170.014
taxisGO:00423303040.014
anion transportGO:0006820410.014
actin cytoskeleton organizationGO:00300362060.014
exocrine system developmentGO:00352721620.014
muscle organ developmentGO:00075171270.014
carbohydrate derivative metabolic processGO:19011352170.014
head developmentGO:00603221350.014
actin filament based processGO:00300292200.014
regulation of multicellular organismal developmentGO:20000264140.014
sensory perception of painGO:001923340.014
regulation of gene expression epigeneticGO:00400291280.013
response to woundingGO:0009611940.013
response to lipopolysaccharideGO:003249640.013
organic acid metabolic processGO:00060821030.013
positive regulation of developmental processGO:00510941430.013
secretionGO:00469031090.013
rna processingGO:00063961470.013
tissue morphogenesisGO:00487292970.013
protein transportGO:00150311550.013
response to hexoseGO:000974630.013
columnar cuboidal epithelial cell developmentGO:00020662490.013
posttranscriptional regulation of gene expressionGO:00106081450.013
cell adhesionGO:00071551360.013
regulation of molecular functionGO:00650092170.013
sensory organ morphogenesisGO:00905962600.013
negative regulation of cell communicationGO:00106482230.013
regulation of cell differentiationGO:00455953020.013
mrna processingGO:00063971040.013
segmentationGO:00352822070.013
cellular macromolecular complex assemblyGO:00346221530.013
biological adhesionGO:00226101380.013
response to oxygen levelsGO:0070482590.012
chemotaxisGO:00069352490.012
monocarboxylic acid transportGO:001571830.012
developmental programmed cell deathGO:00106231380.012
negative regulation of response to stimulusGO:00485852580.012
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.012
regulation of catalytic activityGO:00507901850.012
cellular amine metabolic processGO:0044106120.012
synaptic transmissionGO:00072682880.012
mrna metabolic processGO:00160711240.012
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.012
response to biotic stimulusGO:00096072940.012
signal transduction by phosphorylationGO:00230141070.012
embryonic morphogenesisGO:00485982060.012
dendrite morphogenesisGO:00488131990.012
respiratory system developmentGO:00605412130.012
mitochondrion organizationGO:0007005650.012
phenol containing compound metabolic processGO:0018958570.012
response to alcoholGO:0097305950.012
purine containing compound metabolic processGO:00725211550.012
response to organonitrogen compoundGO:0010243750.012
chromatin organizationGO:00063252070.012
organic substance catabolic processGO:19015753080.012
secretion by cellGO:00329401010.012
positive regulation of cell migrationGO:003033520.012
macromolecule catabolic processGO:00090571610.012
phosphate ion transportGO:000681740.012
regulation of transportGO:00510491810.012
axon guidanceGO:00074112330.012
single organism cellular localizationGO:19025801800.012
multicellular organismal agingGO:00102591400.012
organelle localizationGO:00516401480.012
regulation of immune responseGO:00507761180.012
organic hydroxy compound metabolic processGO:1901615830.012
response to glucoseGO:000974920.012
cellular macromolecule catabolic processGO:00442651360.012
cellular macromolecule localizationGO:00707272200.011
establishment of protein localizationGO:00451841630.011
regulation of cell shapeGO:00083601130.011
axonogenesisGO:00074092900.011
mesenchymal cell differentiationGO:004876210.011
wound healingGO:0042060750.011
sodium dependent phosphate transportGO:004434120.011
telencephalon developmentGO:002153720.011
positive regulation of phosphorylationGO:0042327870.011
tube developmentGO:00352952440.011
camera type eye developmentGO:004301040.011
tube morphogenesisGO:00352391910.011
mitotic nuclear divisionGO:00070672130.011
salivary gland developmentGO:00074311620.011
eye morphogenesisGO:00485922600.011
regulation of anatomical structure sizeGO:00900661630.011
embryonic pattern specificationGO:00098801740.011
single organism carbohydrate metabolic processGO:0044723720.011
positive regulation of transportGO:0051050920.011
positive regulation of protein metabolic processGO:00512471280.011
negative regulation of cell deathGO:0060548810.011
adult locomotory behaviorGO:0008344760.011
purine nucleotide metabolic processGO:00061631460.011
negative regulation of developmental processGO:00510932010.011
digestive system developmentGO:00551231490.011
mapk cascadeGO:00001651070.011
cation transmembrane transportGO:0098655880.011
ribose phosphate metabolic processGO:00196931450.011
morphogenesis of embryonic epitheliumGO:0016331940.011
response to starvationGO:0042594970.010
digestive tract developmentGO:00485651490.010
regulation of behaviorGO:0050795750.010
regulation of cell cycle processGO:00105641810.010
regulation of cellular localizationGO:00603411360.010
regulation of immune system processGO:00026821760.010
dorsal ventral pattern formation imaginal discGO:0007450510.010
positive regulation of phosphorus metabolic processGO:00105621390.010
neuron projection guidanceGO:00974852410.010
developmental maturationGO:00217001720.010
male meiosisGO:0007140520.010
tissue migrationGO:00901301550.010
cellular response to biotic stimulusGO:007121640.010
regulation of phosphorylationGO:00423251470.010
positive regulation of catalytic activityGO:00430851180.010
regulation of protein modification processGO:00313991120.010
wnt signaling pathwayGO:0016055980.010

LKR disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.018
disease of metabolismDOID:001466700.016
inherited metabolic disorderDOID:65500.012
nervous system diseaseDOID:86300.011