Drosophila melanogaster

41 known processes

pwn (Dmel_CG11101)

pawn

(Aliases: CT31067,l(2)pwn,Dmel\CG11101,CG11101)

pwn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
imaginal disc derived appendage morphogenesisGO:00351143950.166
imaginal disc derived wing morphogenesisGO:00074763370.132
appendage developmentGO:00487364010.113
organonitrogen compound metabolic processGO:19015643180.102
wing disc morphogenesisGO:00074723440.097
lateral inhibitionGO:00463312060.093
regulation of transcription from rna polymerase ii promoterGO:00063573780.075
imaginal disc derived appendage developmentGO:00487373990.071
cell cell signaling involved in cell fate commitmentGO:00451682100.071
appendage morphogenesisGO:00351073970.069
response to abiotic stimulusGO:00096283410.064
cellular amine metabolic processGO:0044106120.055
negative regulation of gene expressionGO:00106293870.055
developmental maturationGO:00217001720.051
chromosome organizationGO:00512763600.051
small molecule metabolic processGO:00442813050.050
endocytosisGO:00068973100.048
negative regulation of cellular metabolic processGO:00313243820.046
positive regulation of rna biosynthetic processGO:19026802660.046
organelle assemblyGO:00709251980.045
carboxylic acid metabolic processGO:0019752920.044
cell motilityGO:00488702510.044
anion homeostasisGO:005508130.044
dendrite morphogenesisGO:00488131990.043
epithelial cell differentiationGO:00308553220.043
catabolic processGO:00090564090.042
positive regulation of macromolecule biosynthetic processGO:00105572830.042
neurological system processGO:00508773580.042
compound eye developmentGO:00487493070.041
cell adhesionGO:00071551360.041
transcription from rna polymerase ii promoterGO:00063663680.040
protein modification processGO:00362114380.040
organic acid metabolic processGO:00060821030.040
regulation of anatomical structure morphogenesisGO:00226032420.040
dendrite developmentGO:00163582040.040
forebrain developmentGO:003090020.039
skin developmentGO:0043588650.039
positive regulation of nucleobase containing compound metabolic processGO:00459353320.039
post embryonic appendage morphogenesisGO:00351203850.038
organic substance catabolic processGO:19015753080.037
vesicle mediated transportGO:00161923810.037
actin filament organizationGO:00070151260.037
amine metabolic processGO:0009308120.037
oxoacid metabolic processGO:00434361030.036
tube developmentGO:00352952440.036
organic hydroxy compound metabolic processGO:1901615830.036
spindle organizationGO:00070512530.036
cell proliferationGO:00082832990.035
localization of cellGO:00516742570.035
regulation of cellular protein metabolic processGO:00322682430.035
tissue morphogenesisGO:00487292970.035
compound eye morphogenesisGO:00017452490.035
ethanolamine containing compound metabolic processGO:004243940.034
regulation of localizationGO:00328792750.034
regulation of organelle organizationGO:00330431960.034
programmed cell deathGO:00125012570.033
establishment of localization in cellGO:00516494020.033
cell deathGO:00082192790.033
response to other organismGO:00517072930.033
regulation of cellular amino acid metabolic processGO:000652100.033
epithelial cell developmentGO:00020642740.033
anterior posterior pattern specificationGO:00099521360.033
single organism behaviorGO:00447083910.032
neuroblast proliferationGO:0007405740.032
cellular amino acid metabolic processGO:0006520610.032
cellular protein modification processGO:00064644380.032
negative regulation of response to stimulusGO:00485852580.032
digestive tract morphogenesisGO:00485461270.031
biological adhesionGO:00226101380.031
regulation of multicellular organismal developmentGO:20000264140.031
negative regulation of signalingGO:00230572190.031
regulation of protein metabolic processGO:00512462560.031
epithelial tube morphogenesisGO:0060562880.031
phagocytosisGO:00069092150.031
regulation of mitotic cell cycleGO:00073461900.030
morphogenesis of an epitheliumGO:00020092760.030
single organism catabolic processGO:00447122280.030
cellular macromolecule localizationGO:00707272200.030
cell migrationGO:00164772380.030
body morphogenesisGO:001017120.030
regulation of cellular amine metabolic processGO:003323830.030
sterol homeostasisGO:005509240.030
respiratory system developmentGO:00605412130.030
positive regulation of rna metabolic processGO:00512542710.029
macromolecular complex assemblyGO:00650032560.029
compound eye photoreceptor cell differentiationGO:00017511400.029
positive regulation of transcription dna templatedGO:00458932660.029
positive regulation of cell migrationGO:003033520.029
response to external biotic stimulusGO:00432072930.028
regulation of transportGO:00510491810.028
intracellular transportGO:00469072280.028
regulation of cell cycleGO:00517262910.028
intracellular signal transductionGO:00355563000.028
phospholipid homeostasisGO:005509110.028
regulation of embryonic developmentGO:0045995680.028
deathGO:00162652840.028
cellular catabolic processGO:00442483720.028
renal system developmentGO:0072001720.028
positive regulation of response to stimulusGO:00485843230.027
histone modificationGO:00165701060.027
mitotic nuclear divisionGO:00070672130.027
neural precursor cell proliferationGO:0061351750.027
positive regulation of gene expressionGO:00106282900.027
defense responseGO:00069523000.027
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.027
positive regulation of macromolecule metabolic processGO:00106044050.027
homeostatic processGO:00425921990.027
positive regulation of signal transductionGO:00099672230.027
mitotic spindle organizationGO:00070522200.027
eye developmentGO:00016543230.027
telencephalon developmentGO:002153720.027
cell divisionGO:00513012480.026
regulation of cellular ketone metabolic processGO:001056530.026
protein complex biogenesisGO:00702712010.026
protein localizationGO:00081042840.026
regulation of epithelial cell differentiationGO:003085640.026
epidermal cell differentiationGO:0009913510.026
gland developmentGO:00487321910.026
chromatin modificationGO:00165681470.025
cellular ketone metabolic processGO:0042180240.025
spindle assemblyGO:0051225800.025
negative regulation of cell communicationGO:00106482230.025
positive regulation of nucleic acid templated transcriptionGO:19035082660.025
nuclear divisionGO:00002803320.025
regulation of epithelial cell proliferationGO:005067840.025
regulation of cell morphogenesisGO:00226041630.025
regulation of cell cycle processGO:00105641810.025
sensory organ morphogenesisGO:00905962600.025
cell maturationGO:00484691440.024
negative regulation of biosynthetic processGO:00098902770.024
kidney developmentGO:000182230.024
cholesterol homeostasisGO:004263230.024
protein maturationGO:0051604710.024
chromatin organizationGO:00063252070.024
open tracheal system developmentGO:00074242040.024
eye photoreceptor cell differentiationGO:00017541450.024
positive regulation of nitrogen compound metabolic processGO:00511733540.024
regulation of cell deathGO:00109411730.024
covalent chromatin modificationGO:00165691060.024
axon developmentGO:00615642970.024
epidermis developmentGO:0008544650.024
organic substance transportGO:00717022570.024
digestive system developmentGO:00551231490.023
cellular nitrogen compound catabolic processGO:00442701650.023
digestive tract developmentGO:00485651490.023
mitotic cytokinesisGO:0000281500.023
single organism intracellular transportGO:19025822070.023
negative regulation of mitotic cell cycleGO:00459301090.022
regulation of response to stressGO:00801342000.022
gland morphogenesisGO:00226121450.022
apoptotic processGO:00069151590.022
negative regulation of cell cycleGO:00457861160.022
establishment of protein localizationGO:00451841630.022
somatic muscle developmentGO:0007525660.022
regulation of chromosome organizationGO:0033044640.022
fat soluble vitamin biosynthetic processGO:004236210.022
vitamin biosynthetic processGO:000911010.022
macromolecule catabolic processGO:00090571610.022
phosphorylationGO:00163102940.021
chemotaxisGO:00069352490.021
regulation of cellular localizationGO:00603411360.021
positive regulation of biosynthetic processGO:00098913160.021
proteolysisGO:00065081920.021
immune response regulating signaling pathwayGO:000276420.021
response to organic substanceGO:00100332840.021
actin cytoskeleton organizationGO:00300362060.021
cognitionGO:00508901410.021
organelle fissionGO:00482853400.021
stem cell differentiationGO:00488631170.021
photoreceptor cell differentiationGO:00465301700.021
hindbrain developmentGO:003090220.021
regulation of growthGO:00400082330.021
tube morphogenesisGO:00352391910.020
negative regulation of cell cycle processGO:00109481090.020
developmental growthGO:00485892800.020
hindgut morphogenesisGO:0007442580.020
salivary gland developmentGO:00074311620.020
regionalizationGO:00030024160.020
fat soluble vitamin metabolic processGO:000677510.020
salivary gland morphogenesisGO:00074351450.020
cuticle developmentGO:0042335860.020
multi organism reproductive behaviorGO:00447051210.020
segmentationGO:00352822070.020
negative regulation of cell differentiationGO:00455961430.020
regulation of molecular functionGO:00650092170.020
negative regulation of macromolecule biosynthetic processGO:00105582700.020
sensory perceptionGO:00076001960.020
nephron epithelium developmentGO:007200930.020
regulation of histone deacetylationGO:003106320.020
regulation of cell shapeGO:00083601130.020
organophosphate metabolic processGO:00196371950.019
regulation of synapse assemblyGO:0051963940.019
gliogenesisGO:0042063800.019
learning or memoryGO:00076111410.019
regulation of anatomical structure sizeGO:00900661630.019
notch signaling pathwayGO:00072191200.019
axis specificationGO:00097981670.019
protein transportGO:00150311550.019
eye morphogenesisGO:00485922600.019
small gtpase mediated signal transductionGO:0007264880.019
glycosyl compound metabolic processGO:19016571270.019
protein modification by small protein conjugationGO:0032446790.019
chaeta developmentGO:0022416970.019
apical constrictionGO:0003383180.019
regulation of proteolysisGO:0030162870.019
positive regulation of cell communicationGO:00106472500.019
defense response to other organismGO:00985422250.019
purine nucleoside metabolic processGO:00422781270.019
exocrine system developmentGO:00352721620.019
ribonucleoside triphosphate metabolic processGO:00091991190.018
positive regulation of cell motilityGO:200014730.018
organonitrogen compound catabolic processGO:19015651280.018
negative regulation of developmental processGO:00510932010.018
negative regulation of signal transductionGO:00099682060.018
locomotory behaviorGO:00076261760.018
regulation of neuron differentiationGO:00456641030.018
response to organophosphorusGO:004668320.018
maintenance of locationGO:0051235730.018
negative regulation of nucleobase containing compound metabolic processGO:00459342610.018
kidney morphogenesisGO:006099330.018
carbohydrate derivative catabolic processGO:19011361180.018
positive regulation of cellular amino acid metabolic processGO:004576400.018
negative regulation of rna metabolic processGO:00512532510.017
organic cyclic compound catabolic processGO:19013611680.017
regulation of cell morphogenesis involved in differentiationGO:0010769610.017
heterocycle catabolic processGO:00467001660.017
regulation of synapse structure and activityGO:00508031280.017
regulation of immune system processGO:00026821760.017
negative regulation of nucleic acid templated transcriptionGO:19035072400.017
negative regulation of nitrogen compound metabolic processGO:00511722650.017
ras protein signal transductionGO:0007265880.017
positive regulation of multicellular organismal processGO:00512401430.017
steroid catabolic processGO:000670610.017
regulation of neurogenesisGO:00507671580.017
stem cell proliferationGO:0072089880.017
multicellular organismal reproductive behaviorGO:00330571100.017
taxisGO:00423303040.017
negative regulation of rna biosynthetic processGO:19026792400.017
response to bacteriumGO:00096171980.017
purine ribonucleoside metabolic processGO:00461281270.017
protein complex assemblyGO:00064612000.017
negative regulation of transcription dna templatedGO:00458922370.017
camera type eye morphogenesisGO:004859320.017
negative regulation of cell cycle phase transitionGO:19019881030.017
stem cell divisionGO:0017145690.017
spermatogenesisGO:00072832000.016
positive regulation of cellular component organizationGO:00511301560.016
regulation of phosphorus metabolic processGO:00511742100.016
spindle assembly involved in mitosisGO:0090307500.016
regulation of defense responseGO:00313471020.016
connective tissue developmentGO:006144830.016
g2 dna damage checkpointGO:0031572690.016
nephron developmentGO:007200630.016
regulation of catalytic activityGO:00507901850.016
protein processingGO:0016485680.016
response to lipopolysaccharideGO:003249640.016
immune system processGO:00023763470.016
positive regulation of lipid storageGO:001088440.016
cellular lipid metabolic processGO:0044255830.016
positive regulation of cellular amine metabolic processGO:003324000.016
positive regulation of transportGO:0051050920.016
positive regulation of signalingGO:00230562430.016
columnar cuboidal epithelial cell differentiationGO:00020652560.016
regulation of cellular component biogenesisGO:00440872010.016
regulation of programmed cell deathGO:00430671520.016
regulation of cell developmentGO:00602842150.016
axon guidanceGO:00074112330.016
rna localizationGO:00064031150.016
chemical homeostasisGO:0048878920.016
embryonic pattern specificationGO:00098801740.016
regulation of cell proliferationGO:00421271630.016
olfactory behaviorGO:0042048970.016
microtubule cytoskeleton organization involved in mitosisGO:1902850520.016
regulation of cell projection organizationGO:0031344920.015
synapse assemblyGO:00074161430.015
embryo development ending in birth or egg hatchingGO:00097921520.015
cellular response to organic substanceGO:00713101320.015
response to glucoseGO:000974920.015
chemosensory behaviorGO:00076351060.015
tripartite regional subdivisionGO:00073511030.015
lipid metabolic processGO:00066291210.015
regulation of mitotic cell cycle phase transitionGO:19019901300.015
neurotransmitter metabolic processGO:004213320.015
histolysisGO:00075591020.015
regulation of cell cycle phase transitionGO:19019871300.015
cellular modified amino acid metabolic processGO:0006575450.015
growthGO:00400073590.015
regulation of gene expression epigeneticGO:00400291280.015
nephron morphogenesisGO:007202830.015
oocyte differentiationGO:00099941450.015
nephron tubule morphogenesisGO:007207830.015
imaginal disc derived leg morphogenesisGO:0007480800.015
gene silencingGO:00164581380.015
response to organic cyclic compoundGO:0014070890.015
leg disc morphogenesisGO:0007478800.015
axonogenesisGO:00074092900.015
cellular protein localizationGO:00346131600.015
regulation of multi organism processGO:00439001310.015
cuticle pattern formationGO:0035017270.015
cellular response to chemical stimulusGO:00708871990.015
regulation of catabolic processGO:00098941700.015
kidney epithelium developmentGO:007207330.015
behavioral response to painGO:004826630.015
polyol biosynthetic processGO:004617330.015
positive regulation of catabolic processGO:00098961050.015
regulation of developmental growthGO:00486381740.014
stem cell developmentGO:0048864790.014
nucleoside phosphate metabolic processGO:00067531620.014
urogenital system developmentGO:0001655720.014
embryonic morphogenesisGO:00485982060.014
rna processingGO:00063961470.014
acylglycerol catabolic processGO:004646430.014
mitotic cell cycle checkpointGO:0007093880.014
detection of stimulus involved in sensory perceptionGO:0050906920.014
neuron fate commitmentGO:0048663500.014
posttranscriptional regulation of gene expressionGO:00106081450.014
purine ribonucleoside triphosphate metabolic processGO:00092051190.014
microtubule organizing center organizationGO:00310231680.014
male gamete generationGO:00482322010.014
response to oxygen containing compoundGO:19017002000.014
regulation of embryonic cell shapeGO:0016476300.014
limb developmentGO:006017310.014
cell fate specificationGO:0001708710.014
neuron recognitionGO:00080381010.014
positive regulation of cellular biosynthetic processGO:00313283160.014
ribonucleotide catabolic processGO:00092611090.014
aromatic compound catabolic processGO:00194391660.014
ribonucleoside triphosphate catabolic processGO:00092031080.014
regulation of cellular catabolic processGO:00313291570.014
negative regulation of cellular protein metabolic processGO:0032269850.014
hematopoietic progenitor cell differentiationGO:000224410.014
anterior posterior axis specificationGO:00099481090.014
oocyte axis specificationGO:00073091080.014
purine nucleoside triphosphate metabolic processGO:00091441190.014
negative regulation of cellular component organizationGO:00511291080.014
synaptic growth at neuromuscular junctionGO:00511241190.014
negative regulation of cellular biosynthetic processGO:00313272770.014
intracellular protein transportGO:00068861040.014
endodermal cell differentiationGO:003598730.014
regulation of apoptotic processGO:00429811300.014
mesenchymal cell differentiationGO:004876210.014
regulation of axonogenesisGO:0050770320.014
regulation of sequestering of triglycerideGO:001088930.014
nephron epithelium morphogenesisGO:007208830.014
camera type eye developmentGO:004301040.014
neuromuscular junction developmentGO:00075281490.014
response to hexoseGO:000974630.014
spinal cord developmentGO:002151010.014
protein catabolic processGO:00301631010.014
single organism cellular localizationGO:19025801800.013
eye photoreceptor cell developmentGO:0042462810.013
cellularizationGO:0007349900.013
response to monosaccharideGO:003428440.013
negative regulation of proteolysisGO:0045861310.013
regulation of cell differentiationGO:00455953020.013
wnt signaling pathwayGO:0016055980.013
dorsal ventral pattern formationGO:00099531330.013
tissue migrationGO:00901301550.013
regulation of nervous system developmentGO:00519602480.013
vitamin metabolic processGO:000676620.013
purine containing compound catabolic processGO:00725231120.013
endoderm formationGO:000170630.013
secretionGO:00469031090.013
establishment or maintenance of cell polarityGO:00071631670.013
actin filament based movementGO:0030048260.013
cell cycle phase transitionGO:00447701400.013
triglyceride biosynthetic processGO:001943220.013
reproductive behaviorGO:00190981220.013
peptidyl amino acid modificationGO:00181931050.013
chromosome segregationGO:00070591570.013
regulation of protein modification processGO:00313991120.013
dna metabolic processGO:00062592270.013
central nervous system developmentGO:00074172010.013
cell cell junction organizationGO:0045216550.013
carbohydrate derivative metabolic processGO:19011352170.013
smoothened signaling pathwayGO:0007224490.013
ribonucleoside metabolic processGO:00091191270.013
peptidyl proline hydroxylationGO:001951110.013
regulation of phosphate metabolic processGO:00192202100.013
positive regulation of histone deacetylationGO:003106520.013
positive regulation of catalytic activityGO:00430851180.013
regulation of intracellular signal transductionGO:19025312360.013
epithelial cell morphogenesisGO:0003382250.013
insecticide catabolic processGO:004670110.013
sensory perception of painGO:001923340.013
sister chromatid segregationGO:0000819920.013
purine nucleoside triphosphate catabolic processGO:00091461080.013
phosphatidylethanolamine metabolic processGO:004633710.013
oxidation reduction processGO:00551141230.012
retina development in camera type eyeGO:006004140.012
phenol containing compound metabolic processGO:0018958570.012
retina morphogenesis in camera type eyeGO:006004220.012
positive regulation of protein metabolic processGO:00512471280.012
head developmentGO:00603221350.012
response to biotic stimulusGO:00096072940.012
response to copper ionGO:004668840.012
regulation of response to external stimulusGO:00321011150.012
cellular macromolecular complex assemblyGO:00346221530.012
nucleobase containing compound catabolic processGO:00346551650.012
peripheral nervous system developmentGO:0007422520.012
regulation of i kappab kinase nf kappab signalingGO:004312220.012
lipopolysaccharide mediated signaling pathwayGO:003166310.012
regulation of wnt signaling pathwayGO:0030111680.012
regulation of reproductive processGO:2000241540.012
nucleoside metabolic processGO:00091161270.012
oocyte developmentGO:00485991240.012
anterior posterior axis specification embryoGO:00085951030.012
endodermal cell fate commitmentGO:000171130.012
response to extracellular stimulusGO:00099911160.012
negative regulation of epithelial cell proliferationGO:005068040.012
mitotic cell cycle phase transitionGO:00447721380.012
compound eye photoreceptor developmentGO:0042051780.012
leg disc developmentGO:0035218920.012
photoreceptor cell fate commitmentGO:0046552410.012
protein modification by small protein conjugation or removalGO:00706471060.012
ribose phosphate metabolic processGO:00196931450.012
glycosyl compound catabolic processGO:19016581120.012
endomembrane system organizationGO:00102561190.012
purine ribonucleotide catabolic processGO:00091541090.012
embryonic hindgut morphogenesisGO:0048619480.012
cellular response to lipopolysaccharideGO:007122230.012
negative regulation of nervous system developmentGO:0051961920.012
hair cell differentiationGO:0035315470.012
purine nucleotide catabolic processGO:00061951090.012
eye antennal disc developmentGO:0035214600.012
embryonic axis specificationGO:00005781070.012
ameboidal type cell migrationGO:00016671510.012
regulation of protein deacetylationGO:009031120.012
nucleotide metabolic processGO:00091171610.012
nephron tubule developmentGO:007208030.012
regulation of synapse organizationGO:00508071100.012
gastrulation involving germ band extensionGO:0010004360.012
response to endogenous stimulusGO:00097191190.012
cytoplasmic transportGO:00164821300.012
response to painGO:004826530.012
imaginal disc derived wing vein specificationGO:0007474480.012
cell recognitionGO:00080371020.012
defense response to bacteriumGO:00427421780.012
cholesterol transportGO:003030120.012
organophosphate catabolic processGO:00464341120.012
eggshell formationGO:00307031050.012
brain developmentGO:00074201200.012
glial cell differentiationGO:0010001350.012
synapse organizationGO:00508081960.012
immune responseGO:00069552460.012
germarium derived egg chamber formationGO:00072931010.012
organonitrogen compound biosynthetic processGO:19015661170.012
intracellular protein transmembrane transportGO:006500240.012
multi multicellular organism processGO:00447061230.012
malpighian tubule developmentGO:0072002640.012
morphogenesis of embryonic epitheliumGO:0016331940.012
single organism membrane organizationGO:0044802930.012
regulation of endocytosisGO:0030100370.012
negative regulation of cell deathGO:0060548810.011
cellular response to molecule of bacterial originGO:007121930.011
renal tubule developmentGO:0061326640.011
regulation of cell substrate adhesionGO:001081020.011
substrate adhesion dependent cell spreadingGO:003444620.011
gastrulationGO:0007369700.011
proteolysis involved in cellular protein catabolic processGO:0051603830.011
nucleoside phosphate catabolic processGO:19012921100.011
neuron projection guidanceGO:00974852410.011
response to temperature stimulusGO:00092661060.011
hindgut developmentGO:0061525580.011
regulation of phosphorylationGO:00423251470.011
positive regulation of phosphate metabolic processGO:00459371390.011
actin filament based processGO:00300292200.011
cellular protein catabolic processGO:0044257830.011
glandular epithelial cell differentiationGO:000206710.011
positive regulation of protein deacetylationGO:009031220.011
regulation of lipid transportGO:003236830.011
oocyte constructionGO:00073081120.011
protein ubiquitinationGO:0016567700.011
multicellular organismal agingGO:00102591400.011
negative regulation of mitotic cell cycle phase transitionGO:19019911030.011
embryonic development via the syncytial blastodermGO:00017001480.011
regulation of sterol transportGO:003237110.011
pyridine nucleotide metabolic processGO:001936220.011
establishment of planar polarityGO:0001736870.011

pwn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.098
musculoskeletal system diseaseDOID:1700.021
disease of cellular proliferationDOID:1456600.020
organ system cancerDOID:005068600.020
cancerDOID:16200.020
kidney diseaseDOID:55700.020
urinary system diseaseDOID:1800.020
nervous system diseaseDOID:86300.018
cardiovascular system diseaseDOID:128700.017
artery diseaseDOID:005082800.015
vascular diseaseDOID:17800.015
hypertensionDOID:1076300.015
disease of metabolismDOID:001466700.014
inherited metabolic disorderDOID:65500.014
connective tissue diseaseDOID:6500.012
bone diseaseDOID:008000100.012