Drosophila melanogaster

5 known processes

Trxr-2 (Dmel_CG11401)

thioredoxin reductase 2

(Aliases: Trxr2,CG11401,Dmel\CG11401,DmTrxR-2,trxr-2)

Trxr-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
small molecule metabolic processGO:00442813050.071
cellular catabolic processGO:00442483720.068
endocytosisGO:00068973100.068
catabolic processGO:00090564090.066
phagocytosisGO:00069092150.063
appendage developmentGO:00487364010.061
vesicle mediated transportGO:00161923810.061
post embryonic appendage morphogenesisGO:00351203850.059
organic substance catabolic processGO:19015753080.058
appendage morphogenesisGO:00351073970.046
organonitrogen compound metabolic processGO:19015643180.045
nucleobase containing compound catabolic processGO:00346551650.043
response to monosaccharideGO:003428440.043
positive regulation of nitrogen compound metabolic processGO:00511733540.043
positive regulation of catabolic processGO:00098961050.042
oxoacid metabolic processGO:00434361030.041
heterocycle catabolic processGO:00467001660.041
carbohydrate derivative metabolic processGO:19011352170.041
imaginal disc derived appendage developmentGO:00487373990.038
negative regulation of gene expressionGO:00106293870.038
imaginal disc derived appendage morphogenesisGO:00351143950.037
negative regulation of biosynthetic processGO:00098902770.037
wing disc morphogenesisGO:00074723440.036
negative regulation of cellular metabolic processGO:00313243820.036
body morphogenesisGO:001017120.036
regionalizationGO:00030024160.035
response to organophosphorusGO:004668320.035
carboxylic acid metabolic processGO:0019752920.035
positive regulation of signalingGO:00230562430.034
positive regulation of cellular biosynthetic processGO:00313283160.034
transcription from rna polymerase ii promoterGO:00063663680.033
imaginal disc derived wing morphogenesisGO:00074763370.032
positive regulation of response to stimulusGO:00485843230.031
cell cell signaling involved in cell fate commitmentGO:00451682100.031
aromatic compound catabolic processGO:00194391660.031
response to lipopolysaccharideGO:003249640.030
negative regulation of macromolecule biosynthetic processGO:00105582700.030
protein modification processGO:00362114380.030
organic cyclic compound catabolic processGO:19013611680.030
negative regulation of cellular biosynthetic processGO:00313272770.029
purine ribonucleoside triphosphate catabolic processGO:00092071080.029
positive regulation of nucleobase containing compound metabolic processGO:00459353320.028
programmed cell deathGO:00125012570.028
response to organic substanceGO:00100332840.028
deathGO:00162652840.027
cellular nitrogen compound catabolic processGO:00442701650.027
regulation of phosphorus metabolic processGO:00511742100.027
response to hexoseGO:000974630.026
regulation of catabolic processGO:00098941700.026
positive regulation of cell communicationGO:00106472500.026
positive regulation of macromolecule metabolic processGO:00106044050.026
regulation of cellular catabolic processGO:00313291570.026
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.026
purine nucleoside metabolic processGO:00422781270.026
regulation of transcription from rna polymerase ii promoterGO:00063573780.026
organic acid metabolic processGO:00060821030.026
nucleotide metabolic processGO:00091171610.026
negative regulation of nitrogen compound metabolic processGO:00511722650.025
intracellular signal transductionGO:00355563000.025
cell deathGO:00082192790.025
purine containing compound metabolic processGO:00725211550.024
purine nucleoside catabolic processGO:00061521120.024
nucleoside catabolic processGO:00091641120.024
cellular protein modification processGO:00064644380.024
regulation of localizationGO:00328792750.024
establishment of localization in cellGO:00516494020.024
renal system processGO:0003014120.024
regulation of cellular ketone metabolic processGO:001056530.024
positive regulation of nucleic acid templated transcriptionGO:19035082660.024
single organism biosynthetic processGO:00447112060.024
carbohydrate derivative catabolic processGO:19011361180.024
positive regulation of signal transductionGO:00099672230.024
purine ribonucleoside metabolic processGO:00461281270.023
ribose phosphate metabolic processGO:00196931450.023
homeostatic processGO:00425921990.023
positive regulation of phosphorus metabolic processGO:00105621390.023
purine nucleotide catabolic processGO:00061951090.023
organonitrogen compound catabolic processGO:19015651280.023
positive regulation of cellular catabolic processGO:0031331950.023
organic substance transportGO:00717022570.023
negative regulation of nucleic acid templated transcriptionGO:19035072400.023
positive regulation of phosphate metabolic processGO:00459371390.023
response to other organismGO:00517072930.023
purine containing compound catabolic processGO:00725231120.022
positive regulation of macromolecule biosynthetic processGO:00105572830.022
phosphorylationGO:00163102940.022
lateral inhibitionGO:00463312060.022
positive regulation of biosynthetic processGO:00098913160.022
negative regulation of rna metabolic processGO:00512532510.022
camera type eye developmentGO:004301040.022
macromolecule catabolic processGO:00090571610.022
ribonucleotide metabolic processGO:00092591450.022
regulation of cell differentiationGO:00455953020.022
positive regulation of rna metabolic processGO:00512542710.022
organophosphate metabolic processGO:00196371950.022
ribonucleoside triphosphate metabolic processGO:00091991190.021
purine ribonucleoside triphosphate metabolic processGO:00092051190.021
organelle fissionGO:00482853400.021
cellular response to chemical stimulusGO:00708871990.021
nucleobase containing small molecule metabolic processGO:00550861740.021
purine ribonucleotide catabolic processGO:00091541090.021
regulation of phosphate metabolic processGO:00192202100.021
single organism catabolic processGO:00447122280.021
cellular amino acid metabolic processGO:0006520610.021
cellular ketone metabolic processGO:0042180240.021
nucleoside phosphate catabolic processGO:19012921100.021
nucleoside triphosphate metabolic processGO:00091411200.020
regulation of molecular functionGO:00650092170.020
response to oxygen containing compoundGO:19017002000.020
response to abiotic stimulusGO:00096283410.020
Rat
positive regulation of nucleoside metabolic processGO:0045979470.020
macromolecular complex assemblyGO:00650032560.020
ribonucleotide catabolic processGO:00092611090.020
cholesterol homeostasisGO:004263230.020
mitotic nuclear divisionGO:00070672130.020
regulation of transportGO:00510491810.020
cellular response to organic substanceGO:00713101320.019
spermatogenesisGO:00072832000.019
single organism carbohydrate metabolic processGO:0044723720.019
ribonucleoside catabolic processGO:00424541120.019
amine metabolic processGO:0009308120.019
negative regulation of signal transductionGO:00099682060.019
regulation of multicellular organismal developmentGO:20000264140.019
sterol homeostasisGO:005509240.019
cell divisionGO:00513012480.019
mitotic spindle organizationGO:00070522200.019
positive regulation of hydrolase activityGO:0051345780.019
spindle organizationGO:00070512530.019
positive regulation of transcription dna templatedGO:00458932660.019
regulation of cellular amine metabolic processGO:003323830.018
response to temperature stimulusGO:00092661060.018
nucleoside triphosphate catabolic processGO:00091431080.018
ribonucleoside triphosphate catabolic processGO:00092031080.018
glycosyl compound metabolic processGO:19016571270.018
protein transportGO:00150311550.018
purine nucleotide metabolic processGO:00061631460.018
protein complex biogenesisGO:00702712010.018
imaginal disc pattern formationGO:0007447910.018
negative regulation of cell communicationGO:00106482230.018
nucleoside phosphate metabolic processGO:00067531620.018
compound eye developmentGO:00487493070.018
purine ribonucleoside monophosphate metabolic processGO:0009167500.018
negative regulation of rna biosynthetic processGO:19026792400.018
proteolysisGO:00065081920.018
response to external biotic stimulusGO:00432072930.017
response to biotic stimulusGO:00096072940.017
renal filtrationGO:009720570.017
apoptotic processGO:00069151590.017
cation transmembrane transportGO:0098655880.017
telencephalon developmentGO:002153720.017
regulation of response to stressGO:00801342000.017
regulation of catalytic activityGO:00507901850.017
regulation of cellular localizationGO:00603411360.017
regulation of cellular amino acid metabolic processGO:000652100.017
nucleotide catabolic processGO:00091661090.017
regulation of cell deathGO:00109411730.017
gland developmentGO:00487321910.017
compound eye morphogenesisGO:00017452490.017
organophosphate catabolic processGO:00464341120.017
segmentationGO:00352822070.017
single organism behaviorGO:00447083910.017
purine nucleoside triphosphate metabolic processGO:00091441190.017
positive regulation of molecular functionGO:00440931360.017
regulation of cellular component biogenesisGO:00440872010.017
nucleoside metabolic processGO:00091161270.017
ras protein signal transductionGO:0007265880.016
atp metabolic processGO:0046034490.016
purine ribonucleotide metabolic processGO:00091501450.016
glycosyl compound catabolic processGO:19016581120.016
regulation of purine nucleotide catabolic processGO:0033121480.016
regulation of hydrolase activityGO:0051336970.016
single organism intracellular transportGO:19025822070.016
ribonucleoside metabolic processGO:00091191270.016
intracellular transportGO:00469072280.016
positive regulation of catalytic activityGO:00430851180.016
chromosome segregationGO:00070591570.016
regulation of intracellular signal transductionGO:19025312360.016
oxidoreduction coenzyme metabolic processGO:000673320.016
cellular amine metabolic processGO:0044106120.016
cellular lipid metabolic processGO:0044255830.015
retina development in camera type eyeGO:006004140.015
oxidation reduction processGO:00551141230.015
neurological system processGO:00508773580.015
carbohydrate metabolic processGO:0005975820.015
kidney developmentGO:000182230.015
dorsal ventral pattern formationGO:00099531330.015
regulation of cell cycleGO:00517262910.015
response to copper ionGO:004668840.015
epithelial cell differentiationGO:00308553220.015
cellular macromolecule catabolic processGO:00442651360.015
cellular response to endogenous stimulusGO:0071495800.015
tissue morphogenesisGO:00487292970.015
regulation of programmed cell deathGO:00430671520.015
cell proliferationGO:00082832990.015
eye developmentGO:00016543230.015
response to bacteriumGO:00096171980.015
nuclear divisionGO:00002803320.015
positive regulation of gene expressionGO:00106282900.015
mapk cascadeGO:00001651070.014
eye morphogenesisGO:00485922600.014
sensory organ morphogenesisGO:00905962600.014
developmental growthGO:00485892800.014
purine nucleoside triphosphate catabolic processGO:00091461080.014
anion homeostasisGO:005508130.014
mating behaviorGO:00076171060.014
morphogenesis of an epitheliumGO:00020092760.014
organelle assemblyGO:00709251980.014
negative regulation of transcription dna templatedGO:00458922370.014
small gtpase mediated signal transductionGO:0007264880.014
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.014
negative regulation of nucleobase containing compound metabolic processGO:00459342610.014
regulation of mitotic cell cycleGO:00073461900.014
ethanolamine containing compound metabolic processGO:004243940.014
negative regulation of developmental processGO:00510932010.014
regulation of nucleotide catabolic processGO:0030811480.014
positive regulation of nucleotide metabolic processGO:0045981550.014
embryo development ending in birth or egg hatchingGO:00097921520.014
response to extracellular stimulusGO:00099911160.014
mrna metabolic processGO:00160711240.014
cellular macromolecular complex assemblyGO:00346221530.014
purine ribonucleoside catabolic processGO:00461301120.014
actin cytoskeleton organizationGO:00300362060.014
response to heatGO:0009408630.013
response to glucoseGO:000974920.013
regulation of protein metabolic processGO:00512462560.013
positive regulation of purine nucleotide catabolic processGO:0033123460.013
photoreceptor cell differentiationGO:00465301700.013
positive regulation of purine nucleotide metabolic processGO:1900544550.013
ribonucleoside monophosphate catabolic processGO:0009158390.013
response to nitrogen compoundGO:1901698900.013
immune system processGO:00023763470.013
regulation of anatomical structure sizeGO:00900661630.013
positive regulation of rna biosynthetic processGO:19026802660.013
negative regulation of cell differentiationGO:00455961430.013
protein localizationGO:00081042840.013
forebrain developmentGO:003090020.013
regulation of cellular protein metabolic processGO:00322682430.013
chromosome organizationGO:00512763600.013
positive regulation of nucleotide catabolic processGO:0030813460.013
gene silencingGO:00164581380.013
cytoplasmic transportGO:00164821300.013
negative regulation of response to stimulusGO:00485852580.013
rna localizationGO:00064031150.013
transmembrane transportGO:00550851390.013
monocarboxylic acid transportGO:001571830.013
signal transduction by phosphorylationGO:00230141070.013
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.013
response to endogenous stimulusGO:00097191190.013
adult behaviorGO:00305341370.013
defense responseGO:00069523000.013
regulation of nucleoside metabolic processGO:0009118500.012
embryonic pattern specificationGO:00098801740.012
regulation of purine nucleotide metabolic processGO:1900542620.012
nicotinamide nucleotide metabolic processGO:004649620.012
synaptic transmissionGO:00072682880.012
developmental maturationGO:00217001720.012
regulation of developmental growthGO:00486381740.012
cation transportGO:00068121100.012
immune response activating signal transductionGO:000275720.012
cellular macromolecule localizationGO:00707272200.012
generation of precursor metabolites and energyGO:0006091420.012
dna metabolic processGO:00062592270.012
cellular response to dna damage stimulusGO:00069742230.012
epithelial cell developmentGO:00020642740.012
innate immune responseGO:00450871440.012
protein complex assemblyGO:00064612000.012
cellular response to external stimulusGO:0071496660.012
regulation of cellular component sizeGO:0032535980.012
endomembrane system organizationGO:00102561190.012
regulation of gene expression epigeneticGO:00400291280.012
ribonucleoside monophosphate metabolic processGO:0009161510.012
regulation of phosphorylationGO:00423251470.012
regulation of apoptotic processGO:00429811300.012
limb developmentGO:006017310.012
gland morphogenesisGO:00226121450.012
wing disc pattern formationGO:0035222660.012
response to nutrient levelsGO:00316671140.012
growthGO:00400073590.012
protein catabolic processGO:00301631010.012
dendrite developmentGO:00163582040.012
actin filament based processGO:00300292200.012
cell motilityGO:00488702510.012
embryonic development via the syncytial blastodermGO:00017001480.012
carbohydrate derivative biosynthetic processGO:1901137850.012
purine nucleoside monophosphate catabolic processGO:0009128380.012
axis specificationGO:00097981670.012
posttranscriptional regulation of gene expressionGO:00106081450.012
positive regulation of cellular amine metabolic processGO:003324000.012
blastoderm segmentationGO:00073501590.012
nucleoside monophosphate metabolic processGO:0009123520.012
regulation of nervous system developmentGO:00519602480.012
neutral lipid biosynthetic processGO:004646020.011
establishment or maintenance of cytoskeleton polarityGO:0030952440.011
exocrine system developmentGO:00352721620.011
salivary gland developmentGO:00074311620.011
adult locomotory behaviorGO:0008344760.011
secretionGO:00469031090.011
secondary metabolic processGO:0019748750.011
enzyme linked receptor protein signaling pathwayGO:00071671790.011
positive regulation of atp catabolic processGO:190329130.011
regulation of immune responseGO:00507761180.011
eye photoreceptor cell differentiationGO:00017541450.011
localization of cellGO:00516742570.011
regulation of mrna metabolic processGO:1903311720.011
camera type eye morphogenesisGO:004859320.011
regulation of nucleotide metabolic processGO:0006140620.011
very long chain fatty acid metabolic processGO:000003840.011
regulation of ras protein signal transductionGO:0046578930.011
negative regulation of signalingGO:00230572190.011
establishment or maintenance of cell polarityGO:00071631670.011
positive regulation of intracellular signal transductionGO:19025331160.011
regulation of immune system processGO:00026821760.011
regulation of organelle organizationGO:00330431960.011
oocyte constructionGO:00073081120.011
cellularizationGO:0007349900.011
purine ribonucleoside monophosphate catabolic processGO:0009169380.011
antimicrobial humoral responseGO:0019730990.011
wnt signaling pathwayGO:0016055980.011
anatomical structure homeostasisGO:0060249970.011
regulation of small gtpase mediated signal transductionGO:0051056930.011
immune response regulating signaling pathwayGO:000276420.011
regulation of cell cycle processGO:00105641810.011
notch signaling pathwayGO:00072191200.011
cellular protein complex assemblyGO:0043623710.011
positive regulation of phosphorylationGO:0042327870.011
organelle localizationGO:00516401480.011
tripartite regional subdivisionGO:00073511030.011
anterior posterior axis specification embryoGO:00085951030.011
immune responseGO:00069552460.011
hematopoietic progenitor cell differentiationGO:000224410.011
somatic muscle developmentGO:0007525660.011
chemical homeostasisGO:0048878920.011
stem cell differentiationGO:00488631170.010
sister chromatid segregationGO:0000819920.010
regulation of cell developmentGO:00602842150.010
nitrogen compound transportGO:0071705850.010
protein phosphorylationGO:00064681690.010
positive regulation of immune responseGO:0050778630.010
maintenance of locationGO:0051235730.010
positive regulation of transportGO:0051050920.010
peptidyl amino acid modificationGO:00181931050.010
monocarboxylic acid metabolic processGO:0032787290.010
dendrite morphogenesisGO:00488131990.010
peptidyl proline modificationGO:001820830.010
secretion by cellGO:00329401010.010
establishment of protein localizationGO:00451841630.010
protein heterooligomerizationGO:005129140.010
cytokinesisGO:0000910900.010
salivary gland morphogenesisGO:00074351450.010
acylglycerol biosynthetic processGO:004646320.010

Trxr-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.039
disease of metabolismDOID:001466700.023
type 2 diabetes mellitusDOID:935200.017
glucose metabolism diseaseDOID:419400.017
diabetes mellitusDOID:935100.017
carbohydrate metabolism diseaseDOID:005001300.017
acquired metabolic diseaseDOID:006015800.017
inherited metabolic disorderDOID:65500.015
nervous system diseaseDOID:86300.015
cardiovascular system diseaseDOID:128700.014
vascular diseaseDOID:17800.011
artery diseaseDOID:005082800.011
musculoskeletal system diseaseDOID:1700.010