IMP: Integrative Multi-species Prediction

Drosophila melanogaster

10 known processes

CG5091 (Dmel_CG5091)

CG5091 gene product from transcript CG5091-RA

(Aliases: Dmel\CG5091)

Entrez: 34409
FLYBASE: FBgn0032234
UniProtKB: M9PB91
UniProtKB: Q9VKX7

Process Predictions
Disease Predictions

CG5091 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
regionalization	GO:0003002	416	0.129
mesoderm development	GO:0007498	78	0.104
mesodermal cell migration	GO:0008078	7	0.092
blastoderm segmentation	GO:0007350	159	0.090
cuticle development	GO:0042335	86	0.079
organonitrogen compound metabolic process	GO:1901564	318	0.072
oxoacid metabolic process	GO:0043436	103	0.066
small molecule metabolic process	GO:0044281	305	0.065
positive regulation of response to stimulus	GO:0048584	323	0.059
embryonic development via the syncytial blastoderm	GO:0001700	148	0.057
ion transmembrane transport	GO:0034220	122	0.055
axon guidance	GO:0007411	233	0.055
multi organism behavior	GO:0051705	175	0.054
intracellular signal transduction	GO:0035556	300	0.054
regulation of localization	GO:0032879	275	0.054
respiratory system development	GO:0060541	213	0.053
steroid catabolic process	GO:0006706	1	0.052
cellular protein modification process	GO:0006464	438	0.050
organic acid metabolic process	GO:0006082	103	0.047
gastrulation with mouth forming first	GO:0001703	36	0.043
epithelial cell migration	GO:0010631	148	0.042
axis specification	GO:0009798	167	0.041
carboxylic acid metabolic process	GO:0019752	92	0.041
response to extracellular stimulus	GO:0009991	116	0.040
negative regulation of response to stimulus	GO:0048585	258	0.039
protein modification process	GO:0036211	438	0.038
negative regulation of signal transduction	GO:0009968	206	0.038
digestive system development	GO:0055123	149	0.037
tissue migration	GO:0090130	155	0.037
regulation of intracellular signal transduction	GO:1902531	236	0.036
oxidation reduction process	GO:0055114	123	0.036
embryonic pattern specification	GO:0009880	174	0.036
tube morphogenesis	GO:0035239	191	0.036
anterior posterior pattern specification	GO:0009952	136	0.035
response to external biotic stimulus	GO:0043207	293	0.035
developmental maturation	GO:0021700	172	0.035
negative regulation of cell communication	GO:0010648	223	0.033
tube development	GO:0035295	244	0.033
digestive tract development	GO:0048565	149	0.032
nucleotide transmembrane transport	GO:1901679	7	0.032
central nervous system development	GO:0007417	201	0.032
regulation of anatomical structure morphogenesis	GO:0022603	242	0.031
camera type eye development	GO:0043010	4	0.031
protein palmitoylation	GO:0018345	2	0.031
positive regulation of signal transduction	GO:0009967	223	0.031
transmembrane transport	GO:0055085	139	0.031
response to lipopolysaccharide	GO:0032496	4	0.031
embryo development ending in birth or egg hatching	GO:0009792	152	0.030
vesicle mediated transport	GO:0016192	381	0.030
eye development	GO:0001654	323	0.029
dorsal ventral pattern formation	GO:0009953	133	0.029
multicellular organismal reproductive behavior	GO:0033057	110	0.028
negative regulation of signaling	GO:0023057	219	0.028
cation transport	GO:0006812	110	0.028
single organism behavior	GO:0044708	391	0.028
catabolic process	GO:0009056	409	0.028
regulation of cell proliferation	GO:0042127	163	0.028
response to organic substance	GO:0010033	284	0.027
cellular response to ethanol	GO:0071361	4	0.027
epithelial cell differentiation	GO:0030855	322	0.027
ameboidal type cell migration	GO:0001667	151	0.027
regulation of multicellular organismal development	GO:2000026	414	0.026
ras protein signal transduction	GO:0007265	88	0.026
gastrulation involving germ band extension	GO:0010004	36	0.026
body morphogenesis	GO:0010171	2	0.026
positive regulation of signaling	GO:0023056	243	0.026
cell migration	GO:0016477	238	0.025
response to abiotic stimulus	GO:0009628	341	0.025
negative regulation of intracellular signal transduction	GO:1902532	57	0.025
regulation of notch signaling pathway	GO:0008593	100	0.025
segment specification	GO:0007379	33	0.025
tissue morphogenesis	GO:0048729	297	0.025
imaginal disc pattern formation	GO:0007447	91	0.025
sensory perception	GO:0007600	196	0.025
regulation of response to stress	GO:0080134	200	0.024
endocytosis	GO:0006897	310	0.024
xenobiotic catabolic process	GO:0042178	1	0.024
morphogenesis of an epithelium	GO:0002009	276	0.024
cellular amino acid metabolic process	GO:0006520	61	0.024
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.024
negative regulation of developmental process	GO:0051093	201	0.023
response to other organism	GO:0051707	293	0.023
mating	GO:0007618	120	0.023
regulation of ras protein signal transduction	GO:0046578	93	0.023
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.023
cellular ketone metabolic process	GO:0042180	24	0.023
regulation of cell cycle	GO:0051726	291	0.023
open tracheal system development	GO:0007424	204	0.023
regulation of immune system process	GO:0002682	176	0.022
cell migration involved in gastrulation	GO:0042074	9	0.022
small gtpase mediated signal transduction	GO:0007264	88	0.022
chemotaxis	GO:0006935	249	0.022
cell motility	GO:0048870	251	0.022
positive regulation of cell communication	GO:0010647	250	0.022
carbohydrate derivative metabolic process	GO:1901135	217	0.022
retina development in camera type eye	GO:0060041	4	0.022
cholesterol transport	GO:0030301	2	0.022
rna processing	GO:0006396	147	0.022
organic substance transport	GO:0071702	257	0.022
chromatin organization	GO:0006325	207	0.021
multi multicellular organism process	GO:0044706	123	0.021
neuron projection guidance	GO:0097485	241	0.021
response to alcohol	GO:0097305	95	0.021
macromolecular complex assembly	GO:0065003	256	0.021
l amino acid import	GO:0043092	2	0.021
endoderm formation	GO:0001706	3	0.021
embryonic morphogenesis	GO:0048598	206	0.021
response to oxygen containing compound	GO:1901700	200	0.020
gland development	GO:0048732	191	0.020
positive regulation of cellular biosynthetic process	GO:0031328	316	0.020
segmentation	GO:0035282	207	0.020
columnar cuboidal epithelial cell development	GO:0002066	249	0.020
cell cell junction assembly	GO:0007043	38	0.019
cholesterol homeostasis	GO:0042632	3	0.019
oocyte axis specification	GO:0007309	108	0.019
rrna processing	GO:0006364	3	0.019
regulation of growth	GO:0040008	233	0.019
epithelium migration	GO:0090132	148	0.019
regulation of intracellular protein transport	GO:0033157	46	0.019
localization of cell	GO:0051674	257	0.019
neurological system process	GO:0050877	358	0.018
cellular macromolecule localization	GO:0070727	220	0.018
phagocytosis	GO:0006909	215	0.018
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.018
taxis	GO:0042330	304	0.018
apoptotic process	GO:0006915	159	0.018
regulation of cellular amine metabolic process	GO:0033238	3	0.018
l glutamate import	GO:0051938	1	0.018
digestive tract morphogenesis	GO:0048546	127	0.018
cellular lipid metabolic process	GO:0044255	83	0.018
notch signaling pathway	GO:0007219	120	0.018
nitrogen compound transport	GO:0071705	85	0.018
regulation of cytoskeleton organization	GO:0051493	89	0.018
dorsal closure	GO:0007391	79	0.018
protein catabolic process	GO:0030163	101	0.018
chemical homeostasis	GO:0048878	92	0.017
androgen metabolic process	GO:0008209	1	0.017
regulation of catalytic activity	GO:0050790	185	0.017
mesoderm morphogenesis	GO:0048332	22	0.017
growth	GO:0040007	359	0.017
regulation of cell cycle process	GO:0010564	181	0.017
response to starvation	GO:0042594	97	0.017
axon development	GO:0061564	297	0.017
segment polarity determination	GO:0007367	25	0.017
apical junction assembly	GO:0043297	32	0.017
immune system process	GO:0002376	347	0.017
vitamin metabolic process	GO:0006766	2	0.017
regulation of cell development	GO:0060284	215	0.017
estrogen metabolic process	GO:0008210	1	0.017
amine metabolic process	GO:0009308	12	0.017
negative regulation of cell death	GO:0060548	81	0.017
cellular homeostasis	GO:0019725	80	0.017
mitotic cell cycle phase transition	GO:0044772	138	0.017
synaptic transmission	GO:0007268	288	0.017
secondary metabolic process	GO:0019748	75	0.017
carbohydrate metabolic process	GO:0005975	82	0.017
cell proliferation	GO:0008283	299	0.017
intracellular mrna localization involved in anterior posterior axis specification	GO:0060811	53	0.016
organic substance catabolic process	GO:1901575	308	0.016
dna metabolic process	GO:0006259	227	0.016
ion transport	GO:0006811	145	0.016
establishment of protein localization	GO:0045184	163	0.016
cellular catabolic process	GO:0044248	372	0.016
neutral lipid biosynthetic process	GO:0046460	2	0.016
single organism cellular localization	GO:1902580	180	0.016
anterior posterior axis specification embryo	GO:0008595	103	0.016
cellular response to chemical stimulus	GO:0070887	199	0.016
carbohydrate derivative biosynthetic process	GO:1901137	85	0.016
cellular response to abiotic stimulus	GO:0071214	58	0.016
regulation of apoptotic process	GO:0042981	130	0.016
oocyte differentiation	GO:0009994	145	0.016
response to ethanol	GO:0045471	59	0.016
meiotic cell cycle	GO:0051321	171	0.016
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.016
single organism biosynthetic process	GO:0044711	206	0.016
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.016
chromatin modification	GO:0016568	147	0.016
single organism catabolic process	GO:0044712	228	0.016
regulation of cellular ketone metabolic process	GO:0010565	3	0.016
compound eye development	GO:0048749	307	0.015
golgi organization	GO:0007030	66	0.015
negative regulation of transcription dna templated	GO:0045892	237	0.015
programmed cell death	GO:0012501	257	0.015
regulation of programmed cell death	GO:0043067	152	0.015
gastrulation	GO:0007369	70	0.015
response to nutrient levels	GO:0031667	114	0.015
cellular amine metabolic process	GO:0044106	12	0.015
response to biotic stimulus	GO:0009607	294	0.015
cell maturation	GO:0048469	144	0.015
benzene containing compound metabolic process	GO:0042537	3	0.015
chromatin remodeling	GO:0006338	72	0.015
positive regulation of cell migration	GO:0030335	2	0.015
positive regulation of phosphorus metabolic process	GO:0010562	139	0.015
eye morphogenesis	GO:0048592	260	0.015
tripartite regional subdivision	GO:0007351	103	0.015
regulation of phosphorylation	GO:0042325	147	0.015
negative regulation of gene expression	GO:0010629	387	0.015
regulation of cellular component biogenesis	GO:0044087	201	0.015
regulation of protein metabolic process	GO:0051246	256	0.014
response to bacterium	GO:0009617	198	0.014
regulation of transport	GO:0051049	181	0.014
ncrna metabolic process	GO:0034660	43	0.014
protein n linked glycosylation	GO:0006487	9	0.014
imaginal disc derived wing morphogenesis	GO:0007476	337	0.014
appendage morphogenesis	GO:0035107	397	0.014
kidney development	GO:0001822	3	0.014
camera type eye morphogenesis	GO:0048593	2	0.014
embryonic axis specification	GO:0000578	107	0.014
regulation of cell death	GO:0010941	173	0.014
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.014
cell junction assembly	GO:0034329	42	0.014
jnk cascade	GO:0007254	50	0.014
defense response to other organism	GO:0098542	225	0.014
meiotic cell cycle process	GO:1903046	132	0.014
regulation of phosphorus metabolic process	GO:0051174	210	0.014
establishment of localization in cell	GO:0051649	402	0.014
regulation of molecular function	GO:0065009	217	0.014
telencephalon development	GO:0021537	2	0.014
regulation of protein modification process	GO:0031399	112	0.014
reproductive behavior	GO:0019098	122	0.014
positive regulation of intracellular signal transduction	GO:1902533	116	0.014
connective tissue development	GO:0061448	3	0.014
regulation of cellular amino acid metabolic process	GO:0006521	0	0.014
epithelial cell development	GO:0002064	274	0.014
intracellular mrna localization	GO:0008298	66	0.014
developmental pigmentation	GO:0048066	68	0.014
cell cycle checkpoint	GO:0000075	95	0.014
signal transduction by phosphorylation	GO:0023014	107	0.014
organonitrogen compound catabolic process	GO:1901565	128	0.013
leg disc development	GO:0035218	92	0.013
regulation of cellular response to stress	GO:0080135	89	0.013
immune response regulating signaling pathway	GO:0002764	2	0.013
hormone catabolic process	GO:0042447	3	0.013
oocyte construction	GO:0007308	112	0.013
cellular response to organic substance	GO:0071310	132	0.013
cellular response to radiation	GO:0071478	52	0.013
chondroitin sulfate metabolic process	GO:0030204	2	0.013
nuclear division	GO:0000280	332	0.013
activation of innate immune response	GO:0002218	4	0.013
dna damage checkpoint	GO:0000077	78	0.013
limb development	GO:0060173	1	0.013
response to light stimulus	GO:0009416	124	0.013
endomembrane system organization	GO:0010256	119	0.013
protein modification by small protein conjugation or removal	GO:0070647	106	0.013
cellular component assembly involved in morphogenesis	GO:0010927	151	0.013
peptidyl amino acid modification	GO:0018193	105	0.013
wnt signaling pathway	GO:0016055	98	0.013
defense response	GO:0006952	300	0.013
regulation of intracellular transport	GO:0032386	64	0.013
gene silencing	GO:0016458	138	0.013
positive regulation of biosynthetic process	GO:0009891	316	0.013
dna integrity checkpoint	GO:0031570	81	0.013
actin filament based movement	GO:0030048	26	0.013
cell death	GO:0008219	279	0.013
response to radiation	GO:0009314	155	0.012
proteolysis	GO:0006508	192	0.012
mapk cascade	GO:0000165	107	0.012
mesoderm formation	GO:0001707	21	0.012
rna localization	GO:0006403	115	0.012
sensory organ morphogenesis	GO:0090596	260	0.012
positive regulation of cell motility	GO:2000147	3	0.012
regulation of nervous system development	GO:0051960	248	0.012
single organism carbohydrate metabolic process	GO:0044723	72	0.012
cellular modified amino acid metabolic process	GO:0006575	45	0.012
lipid metabolic process	GO:0006629	121	0.012
cell growth	GO:0016049	108	0.012
regulation of protein localization	GO:0032880	76	0.012
inorganic ion transmembrane transport	GO:0098660	73	0.012
positive regulation of multicellular organismal process	GO:0051240	143	0.012
acylglycerol biosynthetic process	GO:0046463	2	0.012
cell junction organization	GO:0034330	57	0.012
positive regulation of transport	GO:0051050	92	0.012
positive regulation of macromolecule metabolic process	GO:0010604	405	0.012
death	GO:0016265	284	0.012
endodermal cell differentiation	GO:0035987	3	0.012
oocyte development	GO:0048599	124	0.012
negative regulation of programmed cell death	GO:0043069	72	0.012
sterol homeostasis	GO:0055092	4	0.012
chaeta development	GO:0022416	97	0.012
response to copper ion	GO:0046688	4	0.011
response to organic cyclic compound	GO:0014070	89	0.011
peptidyl lysine modification	GO:0018205	57	0.011
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.011
g2 dna damage checkpoint	GO:0031572	69	0.011
septate junction assembly	GO:0019991	26	0.011
regulation of phosphate metabolic process	GO:0019220	210	0.011
protein heterooligomerization	GO:0051291	4	0.011
mitotic g2 m transition checkpoint	GO:0044818	70	0.011
response to endogenous stimulus	GO:0009719	119	0.011
cell cell junction organization	GO:0045216	55	0.011
sulfur compound metabolic process	GO:0006790	59	0.011
regulation of mitotic cell cycle	GO:0007346	190	0.011
anterior posterior axis specification	GO:0009948	109	0.011
regulation of stress activated mapk cascade	GO:0032872	41	0.011
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.011
positive regulation of catalytic activity	GO:0043085	118	0.011
response to monosaccharide	GO:0034284	4	0.011
defense response to bacterium	GO:0042742	178	0.011
regulation of developmental growth	GO:0048638	174	0.011
learning or memory	GO:0007611	141	0.011
sodium dependent phosphate transport	GO:0044341	2	0.011
g protein coupled receptor signaling pathway	GO:0007186	136	0.011
single organism intracellular transport	GO:1902582	207	0.011
generation of precursor metabolites and energy	GO:0006091	42	0.011
forebrain development	GO:0030900	2	0.011
pronuclear migration	GO:0035046	4	0.011
cell projection assembly	GO:0030031	94	0.011
regulation of protein transport	GO:0051223	57	0.011
cellular amide metabolic process	GO:0043603	80	0.011
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.011
anion transport	GO:0006820	41	0.011
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.011
retina morphogenesis in camera type eye	GO:0060042	2	0.011
receptor clustering	GO:0043113	3	0.011
negative regulation of rna biosynthetic process	GO:1902679	240	0.011
macromolecule catabolic process	GO:0009057	161	0.011
plasma membrane organization	GO:0007009	26	0.011
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.011
endodermal cell fate commitment	GO:0001711	3	0.011
response to organophosphorus	GO:0046683	2	0.011
innate immune response activating signal transduction	GO:0002758	2	0.011
mesenchymal cell development	GO:0014031	1	0.010
negative regulation of notch signaling pathway	GO:0045746	41	0.010
negative regulation of rna metabolic process	GO:0051253	251	0.010
male mating behavior	GO:0060179	70	0.010
adult behavior	GO:0030534	137	0.010
cellular response to nitrogen compound	GO:1901699	51	0.010
protein transport	GO:0015031	155	0.010
regulation of anatomical structure size	GO:0090066	163	0.010
establishment of tissue polarity	GO:0007164	87	0.010
negative regulation of sequestering of calcium ion	GO:0051283	2	0.010
vitamin biosynthetic process	GO:0009110	1	0.010
cell division	GO:0051301	248	0.010
positive regulation of cellular component biogenesis	GO:0044089	80	0.010
eye photoreceptor cell differentiation	GO:0001754	145	0.010
organelle assembly	GO:0070925	198	0.010
head development	GO:0060322	135	0.010
positive regulation of phosphorylation	GO:0042327	87	0.010
positive regulation of protein transport	GO:0051222	37	0.010
regulation of cell morphogenesis	GO:0022604	163	0.010
morphogenesis of a polarized epithelium	GO:0001738	93	0.010
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.010
regulation of response to external stimulus	GO:0032101	115	0.010
negative regulation of growth	GO:0045926	84	0.010
cellular response to extracellular stimulus	GO:0031668	64	0.010
stress activated protein kinase signaling cascade	GO:0031098	55	0.010
regulation of gene expression epigenetic	GO:0040029	128	0.010
meiotic nuclear division	GO:0007126	151	0.010

CG5091 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.019
inherited metabolic disorder	DOID:655	0.011
disease of metabolism	DOID:0014667	0.011

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