Drosophila melanogaster

66 known processes

MED19 (Dmel_CG5546)

Mediator complex subunit 19

(Aliases: CG5546,Dmel\CG5546)

MED19 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of macromolecule metabolic processGO:00106044050.706
axon developmentGO:00615642970.561
regulation of developmental growthGO:00486381740.504
negative regulation of cellular metabolic processGO:00313243820.462
tube developmentGO:00352952440.447
stem cell differentiationGO:00488631170.406
eye morphogenesisGO:00485922600.401
central nervous system developmentGO:00074172010.400
regulation of anatomical structure morphogenesisGO:00226032420.398
dna metabolic processGO:00062592270.394
regulation of multicellular organismal developmentGO:20000264140.392
regulation of response to stressGO:00801342000.365
negative regulation of nucleobase containing compound metabolic processGO:00459342610.352
eye developmentGO:00016543230.344
negative regulation of response to stimulusGO:00485852580.321
positive regulation of macromolecule biosynthetic processGO:00105572830.320
larval developmentGO:00021641040.315
negative regulation of rna metabolic processGO:00512532510.307
growthGO:00400073590.306
compound eye developmentGO:00487493070.300
developmental growthGO:00485892800.288
muscle structure developmentGO:00610612240.257
camera type eye developmentGO:004301040.254
positive regulation of developmental processGO:00510941430.248
digestive tract developmentGO:00485651490.247
sensory organ morphogenesisGO:00905962600.234
positive regulation of gene expressionGO:00106282900.234
negative regulation of signalingGO:00230572190.226
negative regulation of gene expressionGO:00106293870.226
striated muscle cell differentiationGO:0051146900.225
embryo development ending in birth or egg hatchingGO:00097921520.222
regulation of transcription from rna polymerase ii promoterGO:00063573780.215
regulation of intracellular signal transductionGO:19025312360.214
apoptotic signaling pathwayGO:0097190270.214
negative regulation of nitrogen compound metabolic processGO:00511722650.196
positive regulation of nucleic acid templated transcriptionGO:19035082660.191
digestive system developmentGO:00551231490.183
stem cell developmentGO:0048864790.181
tube morphogenesisGO:00352391910.172
compound eye morphogenesisGO:00017452490.170
regulation of cell differentiationGO:00455953020.167
heart developmentGO:0007507820.164
negative regulation of nucleic acid templated transcriptionGO:19035072400.162
immune system developmentGO:0002520570.161
regulation of cell cycle phase transitionGO:19019871300.154
reproductive structure developmentGO:0048608740.144
gonad developmentGO:0008406500.144
negative regulation of cellular biosynthetic processGO:00313272770.142
gastrulationGO:0007369700.142
sex differentiationGO:0007548810.141
cellular catabolic processGO:00442483720.138
reproductive system developmentGO:0061458740.137
macromolecule catabolic processGO:00090571610.136
immune system processGO:00023763470.136
organic substance catabolic processGO:19015753080.135
protein phosphorylationGO:00064681690.133
eye photoreceptor cell differentiationGO:00017541450.132
digestive tract morphogenesisGO:00485461270.129
hematopoietic or lymphoid organ developmentGO:0048534570.129
rna processingGO:00063961470.128
regulation of protein metabolic processGO:00512462560.128
catabolic processGO:00090564090.127
regionalizationGO:00030024160.127
positive regulation of protein metabolic processGO:00512471280.125
negative regulation of biosynthetic processGO:00098902770.119
cell proliferationGO:00082832990.115
negative regulation of signal transductionGO:00099682060.114
wnt signaling pathwayGO:0016055980.110
establishment of localization in cellGO:00516494020.110
cellular protein modification processGO:00064644380.107
cellular macromolecule catabolic processGO:00442651360.101
striated muscle cell developmentGO:0055002500.099
regulation of cell shapeGO:00083601130.098
mrna metabolic processGO:00160711240.097
negative regulation of cell communicationGO:00106482230.096
regulation of growthGO:00400082330.095
protein ubiquitinationGO:0016567700.095
positive regulation of cellular biosynthetic processGO:00313283160.095
positive regulation of developmental growthGO:0048639620.094
development of primary sexual characteristicsGO:0045137500.093
positive regulation of retinal cell programmed cell deathGO:004667090.092
regulation of cellular protein metabolic processGO:00322682430.092
cell fate specificationGO:0001708710.091
cellular response to chemical stimulusGO:00708871990.090
organelle fissionGO:00482853400.086
compound eye photoreceptor cell differentiationGO:00017511400.085
response to other organismGO:00517072930.085
protein localizationGO:00081042840.085
response to heatGO:0009408630.081
molting cycleGO:0042303560.081
regulation of protein modification processGO:00313991120.080
germ cell migrationGO:0008354430.080
positive regulation of nitrogen compound metabolic processGO:00511733540.079
positive regulation of multicellular organismal processGO:00512401430.078
positive regulation of nucleocytoplasmic transportGO:0046824240.078
male mating behaviorGO:0060179700.076
negative regulation of developmental processGO:00510932010.073
smoothened signaling pathwayGO:0007224490.072
mrna processingGO:00063971040.072
transcription from rna polymerase ii promoterGO:00063663680.070
asymmetric cell divisionGO:0008356370.069
rna localizationGO:00064031150.068
negative regulation of developmental growthGO:0048640640.068
small gtpase mediated signal transductionGO:0007264880.066
aromatic compound catabolic processGO:00194391660.065
homeostatic processGO:00425921990.065
apoptotic processGO:00069151590.064
protein modification processGO:00362114380.064
intracellular signal transductionGO:00355563000.064
reproductive behaviorGO:00190981220.062
mesenchymal cell developmentGO:001403110.061
positive regulation of biosynthetic processGO:00098913160.061
multi organism reproductive behaviorGO:00447051210.061
regulation of gene silencingGO:0060968630.060
negative regulation of rna biosynthetic processGO:19026792400.060
positive regulation of signal transductionGO:00099672230.060
camera type eye morphogenesisGO:004859320.058
defense response to bacteriumGO:00427421780.058
cell migrationGO:00164772380.057
response to temperature stimulusGO:00092661060.057
stem cell divisionGO:0017145690.057
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.057
positive regulation of rna metabolic processGO:00512542710.056
regulation of response to external stimulusGO:00321011150.055
proteasomal protein catabolic processGO:0010498590.054
nucleobase containing compound catabolic processGO:00346551650.054
response to organic substanceGO:00100332840.054
mitotic spindle organizationGO:00070522200.053
defense responseGO:00069523000.052
regulation of immune responseGO:00507761180.052
phosphorylationGO:00163102940.051
regulation of cell proliferationGO:00421271630.051
regulation of dna metabolic processGO:0051052340.050
single organism intracellular transportGO:19025822070.050
negative regulation of macromolecule biosynthetic processGO:00105582700.050
regulation of epithelial cell proliferationGO:005067840.049
negative regulation of transcription dna templatedGO:00458922370.048
organic substance transportGO:00717022570.048
macromolecular complex assemblyGO:00650032560.047
regulation of defense responseGO:00313471020.047
innate immune responseGO:00450871440.047
dendrite guidanceGO:0070983210.047
muscle organ developmentGO:00075171270.046
epithelial cell migrationGO:00106311480.046
gliogenesisGO:0042063800.046
rna transportGO:0050658460.046
positive regulation of cell communicationGO:00106472500.046
response to bacteriumGO:00096171980.045
mrna polyadenylationGO:0006378110.045
glial cell differentiationGO:0010001350.043
rna splicingGO:0008380830.043
cellular response to ionizing radiationGO:0071479150.042
brain developmentGO:00074201200.042
cell motilityGO:00488702510.042
mitotic cell cycle phase transitionGO:00447721380.041
cellular response to organic substanceGO:00713101320.041
regulation of cell cycle g1 s phase transitionGO:1902806230.041
regulation of mitotic cell cycle phase transitionGO:19019901300.040
negative regulation of cell differentiationGO:00455961430.040
stem cell proliferationGO:0072089880.040
negative regulation of multicellular organismal processGO:00512411420.039
protein dna complex subunit organizationGO:0071824860.039
positive regulation of molecular functionGO:00440931360.039
negative regulation of cell cycle phase transitionGO:19019881030.039
embryonic morphogenesisGO:00485982060.039
cellular component assembly involved in morphogenesisGO:00109271510.039
stem cell maintenanceGO:0019827670.038
proteolysis involved in cellular protein catabolic processGO:0051603830.038
respiratory system developmentGO:00605412130.038
negative regulation of intracellular signal transductionGO:1902532570.038
positive regulation of rna biosynthetic processGO:19026802660.037
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.037
regulation of immune system processGO:00026821760.037
negative regulation of gene expression epigeneticGO:0045814770.037
ubiquitin dependent protein catabolic processGO:0006511780.037
muscle cell developmentGO:0055001500.036
agingGO:00075681430.036
multicellular organismal reproductive behaviorGO:00330571100.035
gene silencingGO:00164581380.035
hindbrain developmentGO:003090220.034
nitrogen compound transportGO:0071705850.034
modification dependent protein catabolic processGO:0019941780.034
regulation of innate immune responseGO:0045088710.033
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.033
establishment of rna localizationGO:0051236470.032
mrna 3 end processingGO:0031124280.032
positive regulation of response to stimulusGO:00485843230.032
antimicrobial humoral responseGO:0019730990.032
deathGO:00162652840.032
meiosis iGO:0007127590.032
protein complex biogenesisGO:00702712010.031
genitalia developmentGO:0048806260.031
mesenchymal cell differentiationGO:004876210.030
tissue migrationGO:00901301550.030
hemopoiesisGO:0030097460.030
ameboidal type cell migrationGO:00016671510.030
photoreceptor cell differentiationGO:00465301700.030
positive regulation of apoptotic processGO:0043065470.030
negative regulation of cell deathGO:0060548810.029
mitotic nuclear divisionGO:00070672130.029
response to external biotic stimulusGO:00432072930.029
chromosome segregationGO:00070591570.029
cellular response to dna damage stimulusGO:00069742230.028
single organism biosynthetic processGO:00447112060.028
positive regulation of signalingGO:00230562430.028
endocytosisGO:00068973100.028
meiotic chromosome segregationGO:0045132590.028
retina development in camera type eyeGO:006004140.028
regulation of protein catabolic processGO:0042176550.028
protein modification by small protein conjugationGO:0032446790.027
regulation of nucleocytoplasmic transportGO:0046822350.027
cell fate determinationGO:0001709910.027
response to ionizing radiationGO:0010212320.026
regulation of programmed cell deathGO:00430671520.026
organic cyclic compound catabolic processGO:19013611680.026
regulation of cellular response to stressGO:0080135890.026
small molecule metabolic processGO:00442813050.026
positive regulation of cellular component biogenesisGO:0044089800.026
negative regulation of apoptotic processGO:0043066630.026
sister chromatid segregationGO:0000819920.025
proteolysisGO:00065081920.025
muscle cell differentiationGO:00426921030.025
regulation of cellular component sizeGO:0032535980.025
negative regulation of cell cycle processGO:00109481090.025
positive regulation of growthGO:0045927750.025
positive regulation of transcription dna templatedGO:00458932660.025
negative regulation of cell proliferationGO:0008285690.025
endoderm formationGO:000170630.025
positive regulation of cell deathGO:0010942690.025
eggshell formationGO:00307031050.025
response to biotic stimulusGO:00096072940.025
positive regulation of phosphorylationGO:0042327870.025
rna polyadenylationGO:0043631120.024
programmed cell deathGO:00125012570.024
regulation of nurse cell apoptotic processGO:004547790.024
rna cappingGO:003626010.024
response to oxygen containing compoundGO:19017002000.024
regulation of cellular catabolic processGO:00313291570.024
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.024
cellular nitrogen compound catabolic processGO:00442701650.024
spindle elongationGO:0051231830.024
negative regulation of cell cycle g1 s phase transitionGO:1902807130.024
positive regulation of cellular protein metabolic processGO:00322701180.024
response to gamma radiationGO:0010332170.024
response to woundingGO:0009611940.024
regulation of cell morphogenesisGO:00226041630.024
cellular protein catabolic processGO:0044257830.024
regulation of catabolic processGO:00098941700.023
ovarian follicle cell developmentGO:00307072480.023
regulation of response to dna damage stimulusGO:2001020230.023
connective tissue developmentGO:006144830.023
chromatin silencingGO:0006342760.023
cardiovascular system developmentGO:0072358820.022
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.022
body morphogenesisGO:001017120.022
positive regulation of programmed cell deathGO:0043068620.022
spinal cord developmentGO:002151010.022
mapk cascadeGO:00001651070.022
signal transduction by phosphorylationGO:00230141070.022
mitotic spindle elongationGO:0000022810.022
response to abiotic stimulusGO:00096283410.022
axonogenesisGO:00074092900.022
g protein coupled receptor signaling pathwayGO:00071861360.022
regulation of catalytic activityGO:00507901850.022
anatomical structure homeostasisGO:0060249970.022
protein modification by small protein conjugation or removalGO:00706471060.022
cell cycle phase transitionGO:00447701400.022
defense response to other organismGO:00985422250.022
positive regulation of protein modification processGO:0031401580.021
response to light stimulusGO:00094161240.021
regulation of transportGO:00510491810.021
regulation of cellular localizationGO:00603411360.021
meiotic cell cycle processGO:19030461320.021
positive regulation of catabolic processGO:00098961050.021
immune responseGO:00069552460.021
regulation of phosphorylationGO:00423251470.021
dorsal ventral pattern formationGO:00099531330.021
matingGO:00076181200.021
appendage developmentGO:00487364010.020
peptidyl amino acid modificationGO:00181931050.020
cell cycle g1 s phase transitionGO:0044843310.020
positive regulation of nucleobase containing compound metabolic processGO:00459353320.020
regulation of neurogenesisGO:00507671580.020
wing disc pattern formationGO:0035222660.020
multi organism behaviorGO:00517051750.020
multi multicellular organism processGO:00447061230.020
regulation of cell deathGO:00109411730.020
regulation of cytoplasmic transportGO:1903649470.019
regulation of molecular functionGO:00650092170.019
regulation of g1 s transition of mitotic cell cycleGO:2000045230.019
genital disc developmentGO:0035215440.019
sex comb developmentGO:004549880.019
positive regulation of cellular catabolic processGO:0031331950.019
regulation of protein ubiquitinationGO:0031396220.019
rhabdomere developmentGO:0042052380.019
open tracheal system developmentGO:00074242040.019
histone h3 k4 methylationGO:0051568160.018
germ line stem cell maintenanceGO:0030718500.018
defense response to gram negative bacteriumGO:0050829940.018
mating behaviorGO:00076171060.018
activin receptor signaling pathwayGO:003292460.018
cellular protein localizationGO:00346131600.018
regulation of protein phosphorylationGO:0001932640.018
lipid metabolic processGO:00066291210.018
developmental growth involved in morphogenesisGO:0060560650.018
multicellular organismal homeostasisGO:0048871410.018
actin filament based processGO:00300292200.018
maintenance of protein location in cellGO:0032507260.018
nucleobase containing compound transportGO:0015931560.018
epithelial cell type specification open tracheal systemGO:0035153110.018
response to organic cyclic compoundGO:0014070890.017
chromatin organizationGO:00063252070.017
telencephalon developmentGO:002153720.017
positive regulation of intracellular signal transductionGO:19025331160.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.017
regulation of cell cell adhesionGO:0022407210.017
cell divisionGO:00513012480.016
cellular response to abiotic stimulusGO:0071214580.016
limb developmentGO:006017310.016
appendage morphogenesisGO:00351073970.016
tissue morphogenesisGO:00487292970.016
heart morphogenesisGO:0003007320.016
regulation of nervous system developmentGO:00519602480.016
organophosphate catabolic processGO:00464341120.016
negative regulation of protein metabolic processGO:0051248850.016
multicellular organismal agingGO:00102591400.016
circulatory system developmentGO:0072359820.016
positive regulation of mapk cascadeGO:0043410630.016
columnar cuboidal epithelial cell developmentGO:00020662490.016
mrna splicing via spliceosomeGO:0000398730.016
positive regulation of cell differentiationGO:0045597640.016
response to ethanolGO:0045471590.015
response to endogenous stimulusGO:00097191190.015
modification dependent macromolecule catabolic processGO:0043632790.015
regulation of mitotic cell cycleGO:00073461900.015
negative regulation of cellular component organizationGO:00511291080.015
negative regulation of protein modification processGO:0031400290.015
protein complex assemblyGO:00064612000.015
tracheal outgrowth open tracheal systemGO:0007426180.015
enzyme linked receptor protein signaling pathwayGO:00071671790.015
cellular response to endogenous stimulusGO:0071495800.015
protein maturationGO:0051604710.015
regulation of chromosome organizationGO:0033044640.015
purine ribonucleoside triphosphate catabolic processGO:00092071080.014
transcription elongation from rna polymerase ii promoterGO:0006368180.014
intrinsic apoptotic signaling pathwayGO:0097193160.014
positive regulation of transportGO:0051050920.014
negative regulation of cellular protein metabolic processGO:0032269850.014
disaccharide metabolic processGO:000598440.014
posttranscriptional regulation of gene expressionGO:00106081450.014
regulation of hemocyte proliferationGO:0035206370.014
negative regulation of g1 s transition of mitotic cell cycleGO:2000134130.014
taxisGO:00423303040.014
regulation of proteolysisGO:0030162870.014
cellular macromolecular complex assemblyGO:00346221530.014
neuron projection extensionGO:1990138320.014
regulation of cellular ketone metabolic processGO:001056530.014
purine nucleoside metabolic processGO:00422781270.014
o glycan processingGO:001626630.014
neuronal stem cell divisionGO:0036445350.014
guanosine containing compound metabolic processGO:1901068740.013
regulation of intracellular transportGO:0032386640.013
multicellular organism growthGO:0035264460.013
somatic stem cell maintenanceGO:0035019140.013
positive regulation of multicellular organism growthGO:0040018210.013
protein transportGO:00150311550.013
endomembrane system organizationGO:00102561190.013
neurological system processGO:00508773580.013
vesicle mediated transportGO:00161923810.013
compound eye retinal cell programmed cell deathGO:0046667230.013
negative regulation of programmed cell deathGO:0043069720.013
regulation of synapse organizationGO:00508071100.013
positive regulation of phosphorus metabolic processGO:00105621390.012
negative regulation of dna metabolic processGO:0051053120.012
imaginal disc derived wing morphogenesisGO:00074763370.012
extrinsic apoptotic signaling pathwayGO:009719110.012
negative regulation of nervous system developmentGO:0051961920.012
organelle assemblyGO:00709251980.012
regulation of wnt signaling pathwayGO:0030111680.012
cellular lipid metabolic processGO:0044255830.012
developmental programmed cell deathGO:00106231380.012
cytoplasmic transportGO:00164821300.012
actin cytoskeleton organizationGO:00300362060.012
blastoderm segmentationGO:00073501590.012
positive regulation of mitotic cell cycle phase transitionGO:1901992200.012
kidney developmentGO:000182230.012
cell deathGO:00082192790.012
regulation of proteasomal protein catabolic processGO:0061136390.012
regulation of smoothened signaling pathwayGO:0008589280.012
neural precursor cell proliferationGO:0061351750.012
negative regulation of mitotic cell cycleGO:00459301090.011
protein catabolic processGO:00301631010.011
regulation of synapse assemblyGO:0051963940.011
hindgut morphogenesisGO:0007442580.011
head developmentGO:00603221350.011
regulation of cellular component biogenesisGO:00440872010.011
regulation of cell cycleGO:00517262910.011
cellular amine metabolic processGO:0044106120.011
organonitrogen compound metabolic processGO:19015643180.011
positive regulation of intracellular transportGO:0032388420.011
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.011
nucleoside metabolic processGO:00091161270.011
regulation of localizationGO:00328792750.011
neuroblast proliferationGO:0007405740.011
response to ecdysoneGO:0035075340.011
heterocycle catabolic processGO:00467001660.011
cell type specific apoptotic processGO:0097285380.011
muscle fiber developmentGO:0048747120.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101180.010
carbohydrate derivative biosynthetic processGO:1901137850.010
positive regulation of immune system processGO:0002684680.010
embryonic organ developmentGO:0048568500.010
histone modificationGO:00165701060.010
negative regulation of protein processingGO:0010955310.010
regulation of organ morphogenesisGO:2000027780.010
humoral immune responseGO:00069591170.010

MED19 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.124
disease of anatomical entityDOID:700.081
cancerDOID:16200.061
nervous system diseaseDOID:86300.021
motor neuron diseaseDOID:23100.021
central nervous system diseaseDOID:33100.021
neurodegenerative diseaseDOID:128900.021
organ system cancerDOID:005068600.018
musculoskeletal system diseaseDOID:1700.011