IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

Oscp (Dmel_CG4307)

Oligomycin sensitivity-conferring protein

(Aliases: CG4307,OSCP,ATPO_DROME,Dmel\CG4307)

FLYBASE: FBgn0016691
Entrez: 41845
UniProtKB: Q24439

Process Predictions
Disease Predictions

Oscp biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
purine nucleoside metabolic process	GO:0042278	127	0.525	Yeast Worm
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.502	Yeast Worm
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.496	Yeast Worm
embryo development ending in birth or egg hatching	GO:0009792	152	0.490	Worm
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.465	Yeast Worm
nucleobase containing small molecule metabolic process	GO:0055086	174	0.408	Yeast Worm
purine ribonucleoside metabolic process	GO:0046128	127	0.403	Yeast Worm
ribonucleoside metabolic process	GO:0009119	127	0.402	Yeast Worm
small molecule metabolic process	GO:0044281	305	0.400	Yeast Worm
nucleoside metabolic process	GO:0009116	127	0.398	Yeast Worm
nucleoside triphosphate metabolic process	GO:0009141	120	0.373	Yeast Worm
larval development	GO:0002164	104	0.351	Worm
ribose phosphate metabolic process	GO:0019693	145	0.348	Yeast Worm
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.298	Yeast
ribonucleotide metabolic process	GO:0009259	145	0.297	Yeast Worm
purine nucleotide metabolic process	GO:0006163	146	0.291	Yeast Worm
nucleoside monophosphate metabolic process	GO:0009123	52	0.253	Yeast Worm
atp metabolic process	GO:0046034	49	0.239	Yeast Worm
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.230	Yeast Worm
purine containing compound metabolic process	GO:0072521	155	0.228	Yeast Worm
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.210	Yeast Worm
purine containing compound catabolic process	GO:0072523	112	0.208	Yeast
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.203	Yeast Worm
heterocycle catabolic process	GO:0046700	166	0.180	Yeast
aging	GO:0007568	143	0.179	Worm
purine ribonucleotide metabolic process	GO:0009150	145	0.171	Yeast Worm
brain development	GO:0007420	120	0.152
organophosphate metabolic process	GO:0019637	195	0.144	Yeast Worm
glycosyl compound metabolic process	GO:1901657	127	0.143	Yeast Worm
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.137	Yeast
ribonucleoside catabolic process	GO:0042454	112	0.132	Yeast
nucleoside phosphate metabolic process	GO:0006753	162	0.127	Yeast Worm
cellular nitrogen compound catabolic process	GO:0044270	165	0.126	Yeast
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.122	Yeast
nucleobase containing compound catabolic process	GO:0034655	165	0.116	Yeast
nucleotide metabolic process	GO:0009117	161	0.110	Yeast Worm
purine nucleoside catabolic process	GO:0006152	112	0.110	Yeast
atp biosynthetic process	GO:0006754	2	0.103	Yeast Worm
glycosyl compound catabolic process	GO:1901658	112	0.102	Yeast
carbohydrate derivative catabolic process	GO:1901136	118	0.101	Yeast
nucleoside catabolic process	GO:0009164	112	0.099	Yeast
nucleoside triphosphate catabolic process	GO:0009143	108	0.087	Yeast
nucleotide catabolic process	GO:0009166	109	0.086	Yeast
purine nucleotide biosynthetic process	GO:0006164	29	0.085	Yeast Worm
purine ribonucleotide catabolic process	GO:0009154	109	0.085	Yeast
regulation of cell differentiation	GO:0045595	302	0.084
ribonucleotide catabolic process	GO:0009261	109	0.084	Yeast
nucleoside phosphate catabolic process	GO:1901292	110	0.083	Yeast
aromatic compound catabolic process	GO:0019439	166	0.080	Yeast
cellular catabolic process	GO:0044248	372	0.077	Yeast
purine ribonucleoside catabolic process	GO:0046130	112	0.075	Yeast
vesicle mediated transport	GO:0016192	381	0.074
organonitrogen compound metabolic process	GO:1901564	318	0.074	Yeast Worm
carbohydrate derivative metabolic process	GO:1901135	217	0.070	Yeast Worm
organic cyclic compound catabolic process	GO:1901361	168	0.069	Yeast
organic substance catabolic process	GO:1901575	308	0.068	Yeast
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.066	Yeast
catabolic process	GO:0009056	409	0.060	Yeast
oxidation reduction process	GO:0055114	123	0.058
purine nucleotide catabolic process	GO:0006195	109	0.058	Yeast
purine ribonucleoside monophosphate catabolic process	GO:0009169	38	0.057	Yeast
organonitrogen compound catabolic process	GO:1901565	128	0.055	Yeast
single organism catabolic process	GO:0044712	228	0.052	Yeast
endocytosis	GO:0006897	310	0.051
body morphogenesis	GO:0010171	2	0.048
nucleoside phosphate biosynthetic process	GO:1901293	34	0.048	Yeast Worm
phosphorylation	GO:0016310	294	0.048
organic acid metabolic process	GO:0006082	103	0.047
ribonucleoside biosynthetic process	GO:0042455	3	0.045	Yeast Worm
respiratory electron transport chain	GO:0022904	11	0.044
head development	GO:0060322	135	0.039
central nervous system development	GO:0007417	201	0.038
determination of adult lifespan	GO:0008340	137	0.037	Worm
generation of precursor metabolites and energy	GO:0006091	42	0.037
proteolysis	GO:0006508	192	0.037
male gamete generation	GO:0048232	201	0.036
growth	GO:0040007	359	0.036
inorganic cation transmembrane transport	GO:0098662	61	0.036	Yeast Worm
regulation of developmental growth	GO:0048638	174	0.033
purine nucleoside monophosphate catabolic process	GO:0009128	38	0.032	Yeast
negative regulation of rna biosynthetic process	GO:1902679	240	0.032
response to biotic stimulus	GO:0009607	294	0.031
nucleoside monophosphate catabolic process	GO:0009125	39	0.031	Yeast
ribose phosphate biosynthetic process	GO:0046390	28	0.030	Yeast Worm
atp catabolic process	GO:0006200	38	0.030	Yeast
death	GO:0016265	284	0.029	Worm
monovalent inorganic cation transport	GO:0015672	40	0.029	Yeast Worm
multicellular organismal aging	GO:0010259	140	0.029	Worm
organonitrogen compound biosynthetic process	GO:1901566	117	0.028	Yeast Worm
establishment of localization in cell	GO:0051649	402	0.028	Worm
regulation of hemocyte proliferation	GO:0035206	37	0.027
energy derivation by oxidation of organic compounds	GO:0015980	32	0.027
positive regulation of multicellular organismal process	GO:0051240	143	0.027
oxoacid metabolic process	GO:0043436	103	0.027
defense response	GO:0006952	300	0.026
lipid metabolic process	GO:0006629	121	0.026
regulation of multicellular organismal development	GO:2000026	414	0.025
negative regulation of developmental process	GO:0051093	201	0.025
intracellular signal transduction	GO:0035556	300	0.025
purine ribonucleoside monophosphate biosynthetic process	GO:0009168	3	0.025	Yeast Worm
cell death	GO:0008219	279	0.024	Worm
positive regulation of viral process	GO:0048524	2	0.023
nucleotide biosynthetic process	GO:0009165	34	0.023	Yeast Worm
electron transport chain	GO:0022900	14	0.022
regulation of cell development	GO:0060284	215	0.022
cellular respiration	GO:0045333	26	0.021
cation transmembrane transport	GO:0098655	88	0.021	Yeast Worm
response to abiotic stimulus	GO:0009628	341	0.021
regulation of growth	GO:0040008	233	0.020
innate immune response	GO:0045087	144	0.020
ribonucleotide biosynthetic process	GO:0009260	28	0.018	Yeast Worm
negative regulation of response to stimulus	GO:0048585	258	0.018
stem cell proliferation	GO:0072089	88	0.018
regulation of cell death	GO:0010941	173	0.018
spermatid development	GO:0007286	98	0.018
regulation of intracellular signal transduction	GO:1902531	236	0.018
spermatogenesis	GO:0007283	200	0.018
protein destabilization	GO:0031648	2	0.018
apoptotic process	GO:0006915	159	0.018	Worm
molting cycle	GO:0042303	56	0.017
regulation of catalytic activity	GO:0050790	185	0.017
purine nucleoside biosynthetic process	GO:0042451	3	0.017	Yeast Worm
negative regulation of gene expression	GO:0010629	387	0.017
protein complex biogenesis	GO:0070271	201	0.017
cation transport	GO:0006812	110	0.017	Yeast Worm
regulation of neuroblast proliferation	GO:1902692	34	0.016
organophosphate catabolic process	GO:0046434	112	0.016	Yeast
programmed cell death	GO:0012501	257	0.016	Worm
purine containing compound biosynthetic process	GO:0072522	30	0.016	Yeast Worm
regulation of cell proliferation	GO:0042127	163	0.016
neuroblast proliferation	GO:0007405	74	0.015
spinal cord development	GO:0021510	1	0.015
carboxylic acid metabolic process	GO:0019752	92	0.015
negative regulation of purine nucleotide catabolic process	GO:0033122	1	0.015
negative regulation of stem cell proliferation	GO:2000647	30	0.015
negative regulation of cell differentiation	GO:0045596	143	0.015
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.015
mitochondrial atp synthesis coupled electron transport	GO:0042775	8	0.014
reproductive structure development	GO:0048608	74	0.014
regulation of neurogenesis	GO:0050767	158	0.014
negative regulation of signal transduction	GO:0009968	206	0.014
reproductive system development	GO:0061458	74	0.014
cellular protein modification process	GO:0006464	438	0.014
immune response	GO:0006955	246	0.014
regulation of programmed cell death	GO:0043067	152	0.014
multicellular organism growth	GO:0035264	46	0.014
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.013
cell growth	GO:0016049	108	0.013
carbohydrate derivative biosynthetic process	GO:1901137	85	0.013	Yeast Worm
regulation of phosphatase activity	GO:0010921	3	0.013
developmental growth	GO:0048589	280	0.013
response to organic substance	GO:0010033	284	0.012
base excision repair	GO:0006284	2	0.012
response to external biotic stimulus	GO:0043207	293	0.012
ribonucleoside monophosphate biosynthetic process	GO:0009156	3	0.012	Yeast Worm
negative regulation of protein metabolic process	GO:0051248	85	0.012
organelle inheritance	GO:0048308	2	0.012
immune system process	GO:0002376	347	0.012
centrosome organization	GO:0051297	163	0.012
intracellular transport	GO:0046907	228	0.012	Worm
glycosyl compound biosynthetic process	GO:1901659	3	0.012	Yeast Worm
regulation of endopeptidase activity	GO:0052548	36	0.012
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.012
response to organic cyclic compound	GO:0014070	89	0.012
inorganic ion transmembrane transport	GO:0098660	73	0.012	Yeast Worm
negative regulation of nervous system development	GO:0051961	92	0.011
regulation of stem cell proliferation	GO:0072091	40	0.011
single organism behavior	GO:0044708	391	0.011
regulation of striated muscle contraction	GO:0006942	2	0.011
regulation of apoptotic process	GO:0042981	130	0.011
regulation of cellular protein metabolic process	GO:0032268	243	0.011
hematopoietic stem cell differentiation	GO:0060218	1	0.011
regulation of cell cycle	GO:0051726	291	0.011
neurological system process	GO:0050877	358	0.011
organophosphate biosynthetic process	GO:0090407	46	0.011	Yeast Worm
positive regulation of developmental process	GO:0051094	143	0.011
defense response to bacterium	GO:0042742	178	0.011
regulation of viral genome replication	GO:0045069	4	0.011
cellular amino acid metabolic process	GO:0006520	61	0.010
negative regulation of cellular biosynthetic process	GO:0031327	277	0.010
negative regulation of neuron projection development	GO:0010977	9	0.010
positive regulation of binding	GO:0051099	4	0.010
negative regulation of transcription factor import into nucleus	GO:0042992	4	0.010
phagocytosis	GO:0006909	215	0.010
positive regulation of cellular biosynthetic process	GO:0031328	316	0.010

Oscp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
gonadal dysgenesis	DOID:14447	0.079
chromosomal disease	DOID:0080014	0.079
organ system cancer	DOID:0050686	0.018
disease of cellular proliferation	DOID:14566	0.018
cancer	DOID:162	0.018
inherited metabolic disorder	DOID:655	0.012
disease of metabolism	DOID:0014667	0.012

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