Drosophila melanogaster

104 known processes

Vps4 (Dmel_CG6842)

Vacuolar protein sorting 4

(Aliases: CG6842,bcDNA:GH02678,dvps4,Dmel\CG6842,DmBcDNA.GH02678,BcDNA:GH02678,vps4)

Vps4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
deathGO:00162652840.413
Worm
response to oxidative stressGO:0006979860.346
cell deathGO:00082192790.308
Worm
imaginal disc derived appendage developmentGO:00487373990.302
cellular catabolic processGO:00442483720.250
regulation of growthGO:00400082330.234
vacuolar transportGO:0007034130.220
Yeast
cell growthGO:00160491080.217
single organism membrane buddingGO:190259120.213
Yeast
cytoplasmic transportGO:00164821300.184
Human Yeast
actin filament based processGO:00300292200.169
organic substance transportGO:00717022570.162
Human Mouse
modification dependent macromolecule catabolic processGO:0043632790.161
regulation of transcription from rna polymerase ii promoterGO:00063573780.143
developmental growthGO:00485892800.129
dna metabolic processGO:00062592270.125
protein localizationGO:00081042840.118
Yeast
protein transportGO:00150311550.116
actin cytoskeleton organizationGO:00300362060.108
meiotic nuclear divisionGO:00071261510.108
negative regulation of response to stimulusGO:00485852580.104
vesicle mediated transportGO:00161923810.100
establishment of protein localizationGO:00451841630.094
small molecule metabolic processGO:00442813050.091
Human Yeast
organic substance catabolic processGO:19015753080.087
positive regulation of macromolecule metabolic processGO:00106044050.083
endosome transport via multivesicular body sorting pathwayGO:0032509120.080
Human Yeast
meiotic chromosome segregationGO:0045132590.079
single organism intracellular transportGO:19025822070.078
Human Yeast
programmed cell deathGO:00125012570.076
Worm
establishment of localization in cellGO:00516494020.076
Human Yeast
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.074
enzyme linked receptor protein signaling pathwayGO:00071671790.073
cellular macromolecule localizationGO:00707272200.073
Yeast
intracellular transportGO:00469072280.072
Human Yeast
positive regulation of developmental processGO:00510941430.072
negative regulation of signal transductionGO:00099682060.064
regulation of erbb signaling pathwayGO:1901184420.063
ubiquitin dependent protein catabolic processGO:0006511780.063
positive regulation of cellular catabolic processGO:0031331950.063
response to abiotic stimulusGO:00096283410.062
single organism membrane organizationGO:0044802930.058
regulation of transportGO:00510491810.057
Human
axonogenesisGO:00074092900.057
larval midgut histolysisGO:0035069220.057
lateral inhibitionGO:00463312060.055
cellular response to chemical stimulusGO:00708871990.055
membrane organizationGO:00610241120.054
response to other organismGO:00517072930.053
autophagic vacuole assemblyGO:000004520.053
regulation of multi organism processGO:00439001310.053
regulation of synapse structure and activityGO:00508031280.052
positive regulation of protein metabolic processGO:00512471280.052
regulation of anatomical structure morphogenesisGO:00226032420.050
eye morphogenesisGO:00485922600.049
single organism cellular localizationGO:19025801800.048
Yeast
nucleobase containing small molecule metabolic processGO:00550861740.047
Human Yeast
cell motilityGO:00488702510.047
nucleoside catabolic processGO:00091641120.046
Human Yeast
protein targetingGO:0006605640.046
endocytosisGO:00068973100.046
growthGO:00400073590.045
nucleoside phosphate catabolic processGO:19012921100.045
Human Yeast
cellular macromolecule catabolic processGO:00442651360.044
secretion by cellGO:00329401010.043
Human
positive regulation of cellular biosynthetic processGO:00313283160.043
organonitrogen compound metabolic processGO:19015643180.043
Human Yeast
regulation of localizationGO:00328792750.042
Human
appendage developmentGO:00487364010.042
apoptotic processGO:00069151590.042
Worm
regulation of synapse organizationGO:00508071100.042
proteolysis involved in cellular protein catabolic processGO:0051603830.041
regulation of cell projection organizationGO:0031344920.041
membrane buddingGO:000690040.041
Human Yeast
protein phosphorylationGO:00064681690.040
imaginal disc derived wing margin morphogenesisGO:0008587410.039
regulation of neuron projection developmentGO:0010975690.039
molting cycleGO:0042303560.039
Worm
negative regulation of erbb signaling pathwayGO:1901185290.038
regulation of organelle organizationGO:00330431960.038
cellular response to reactive oxygen speciesGO:0034614140.038
cellular response to organic substanceGO:00713101320.038
ribonucleoside metabolic processGO:00091191270.038
Human Yeast
positive regulation of growthGO:0045927750.038
regulation of cell developmentGO:00602842150.038
spindle organizationGO:00070512530.038
synaptic growth at neuromuscular junctionGO:00511241190.037
regulation of cell differentiationGO:00455953020.037
embryo development ending in birth or egg hatchingGO:00097921520.036
Worm
negative regulation of cellular biosynthetic processGO:00313272770.036
aromatic compound catabolic processGO:00194391660.036
Human Yeast
regulation of intracellular protein transportGO:0033157460.035
organophosphate metabolic processGO:00196371950.035
Human Yeast
organelle fissionGO:00482853400.035
negative regulation of nitrogen compound metabolic processGO:00511722650.035
cellular response to external stimulusGO:0071496660.034
ribonucleoside triphosphate metabolic processGO:00091991190.034
Human Yeast
taxisGO:00423303040.034
purine ribonucleoside triphosphate metabolic processGO:00092051190.034
Human Yeast
glycosyl compound metabolic processGO:19016571270.034
Human Yeast
modification dependent protein catabolic processGO:0019941780.033
meiotic cell cycle processGO:19030461320.033
nucleotide metabolic processGO:00091171610.033
Human Yeast
macroautophagyGO:0016236420.033
chromosome segregationGO:00070591570.032
regulation of neuron differentiationGO:00456641030.032
protein modification processGO:00362114380.032
axon guidanceGO:00074112330.031
carbohydrate derivative catabolic processGO:19011361180.031
Human Yeast
protein complex assemblyGO:00064612000.031
Yeast
imaginal disc derived wing morphogenesisGO:00074763370.031
gtp catabolic processGO:0006184720.031
regulation of cell deathGO:00109411730.031
purine nucleotide catabolic processGO:00061951090.030
Human Yeast
chromosome organizationGO:00512763600.030
regulation of cellular localizationGO:00603411360.029
Human
cellular protein catabolic processGO:0044257830.028
cellular protein localizationGO:00346131600.028
Yeast
intracellular protein transportGO:00068861040.028
heterocycle catabolic processGO:00467001660.028
Human Yeast
positive regulation of cellular component organizationGO:00511301560.027
regulation of programmed cell deathGO:00430671520.027
negative regulation of biosynthetic processGO:00098902770.027
autophagyGO:00069141080.026
response to endoplasmic reticulum stressGO:0034976280.026
cellular homeostasisGO:0019725800.026
maintenance of location in cellGO:0051651280.026
Yeast
regulation of cell cycleGO:00517262910.026
Human
negative regulation of cellular response to oxidative stressGO:190040810.026
developmental programmed cell deathGO:00106231380.026
single organism catabolic processGO:00447122280.026
chemotaxisGO:00069352490.026
regulation of cysteine type endopeptidase activityGO:2000116270.026
muscle structure developmentGO:00610612240.025
lipid modificationGO:0030258240.025
positive regulation of nucleic acid templated transcriptionGO:19035082660.025
purine ribonucleoside triphosphate catabolic processGO:00092071080.025
Human Yeast
establishment of organelle localizationGO:00516561220.025
regulation of cellular protein metabolic processGO:00322682430.025
regulation of protein metabolic processGO:00512462560.025
phagocytosisGO:00069092150.025
regulation of molecular functionGO:00650092170.024
organic hydroxy compound metabolic processGO:1901615830.024
Yeast
regulation of vesicle mediated transportGO:0060627590.024
Human
appendage morphogenesisGO:00351073970.024
purine ribonucleoside metabolic processGO:00461281270.024
Human Yeast
regulation of epithelial cell proliferationGO:005067840.024
regulation of developmental growthGO:00486381740.024
regulation of apoptotic processGO:00429811300.024
nucleoside metabolic processGO:00091161270.024
Human Yeast
eye developmentGO:00016543230.024
meiotic cytokinesisGO:0033206330.023
chemical homeostasisGO:0048878920.023
immune response regulating signaling pathwayGO:000276420.023
nucleocytoplasmic transportGO:0006913720.023
defense responseGO:00069523000.023
determination of adult lifespanGO:00083401370.023
ribose phosphate metabolic processGO:00196931450.023
Human Yeast
intracellular signal transductionGO:00355563000.023
neuromuscular junction developmentGO:00075281490.023
positive regulation of cellular protein metabolic processGO:00322701180.023
response to biotic stimulusGO:00096072940.022
organic cyclic compound catabolic processGO:19013611680.022
Human Yeast
regulation of response to stressGO:00801342000.022
positive regulation of molecular functionGO:00440931360.022
regulation of response to external stimulusGO:00321011150.022
purine nucleoside catabolic processGO:00061521120.022
Human Yeast
centrosome organizationGO:00512971630.022
meiotic cell cycleGO:00513211710.021
nuclear transportGO:0051169720.021
nucleoside triphosphate metabolic processGO:00091411200.021
Human Yeast
proteasomal protein catabolic processGO:0010498590.021
transcription from rna polymerase ii promoterGO:00063663680.021
positive regulation of multi organism processGO:0043902400.021
Human
regulation of protein localizationGO:0032880760.021
negative regulation of nucleobase containing compound metabolic processGO:00459342610.020
purine nucleoside triphosphate metabolic processGO:00091441190.020
Human Yeast
leg disc developmentGO:0035218920.020
compound eye developmentGO:00487493070.020
synapse organizationGO:00508081960.020
maintenance of locationGO:0051235730.020
Yeast
negative regulation of rna metabolic processGO:00512532510.020
regulation of cell sizeGO:0008361630.020
purine containing compound metabolic processGO:00725211550.020
Human Yeast
small gtpase mediated signal transductionGO:0007264880.020
secretionGO:00469031090.019
Human
striated muscle cell developmentGO:0055002500.019
regulation of cellular component sizeGO:0032535980.019
response to extracellular stimulusGO:00099911160.019
ribonucleotide catabolic processGO:00092611090.019
Human Yeast
ribonucleoside triphosphate catabolic processGO:00092031080.019
Human Yeast
positive regulation of programmed cell deathGO:0043068620.019
positive regulation of multicellular organismal processGO:00512401430.019
imaginal disc derived appendage morphogenesisGO:00351143950.019
regulation of intracellular signal transductionGO:19025312360.018
positive regulation of cell deathGO:0010942690.018
regulation of locomotionGO:0040012420.018
regulation of cytoskeleton organizationGO:0051493890.018
regulation of cell morphogenesisGO:00226041630.018
regulation of i kappab kinase nf kappab signalingGO:004312220.018
regulation of multicellular organismal developmentGO:20000264140.018
organelle assemblyGO:00709251980.018
positive regulation of hydrolase activityGO:0051345780.018
nucleoside triphosphate catabolic processGO:00091431080.018
Human Yeast
catabolic processGO:00090564090.018
regulation of nervous system developmentGO:00519602480.017
regulation of catalytic activityGO:00507901850.017
interspecies interaction between organismsGO:0044419160.017
positive regulation of gene expressionGO:00106282900.017
inorganic ion transmembrane transportGO:0098660730.017
positive regulation of apoptotic processGO:0043065470.017
actomyosin structure organizationGO:0031032560.017
purine nucleoside metabolic processGO:00422781270.017
Human Yeast
tissue morphogenesisGO:00487292970.017
regulation of hydrolase activityGO:0051336970.017
positive regulation of catabolic processGO:00098961050.017
negative regulation of macromolecule biosynthetic processGO:00105582700.016
regulation of phosphatase activityGO:001092130.016
positive regulation of nitrogen compound metabolic processGO:00511733540.016
positive regulation of nucleobase containing compound metabolic processGO:00459353320.016
protein catabolic processGO:00301631010.016
positive regulation of macromolecule biosynthetic processGO:00105572830.016
positive regulation of phosphate metabolic processGO:00459371390.016
nucleobase containing compound catabolic processGO:00346551650.016
Human Yeast
post embryonic appendage morphogenesisGO:00351203850.016
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.016
inorganic cation transmembrane transportGO:0098662610.016
phosphatidylinositol mediated signalingGO:004801540.016
regulation of cellular ketone metabolic processGO:001056530.016
positive regulation of gtpase activityGO:0043547430.016
immune system processGO:00023763470.016
scf dependent proteasomal ubiquitin dependent protein catabolic processGO:003114610.016
microtubule based movementGO:0007018510.016
g protein coupled receptor signaling pathwayGO:00071861360.016
single organism behaviorGO:00447083910.016
store operated calcium entryGO:000211530.016
phosphorylationGO:00163102940.015
female meiotic divisionGO:0007143700.015
cellular ketone metabolic processGO:0042180240.015
purine containing compound catabolic processGO:00725231120.015
Human Yeast
larval midgut cell programmed cell deathGO:0035096190.015
gtp metabolic processGO:0046039720.015
phospholipid metabolic processGO:0006644230.015
reproductive behaviorGO:00190981220.015
negative regulation of cellular metabolic processGO:00313243820.015
cell cell signaling involved in cell fate commitmentGO:00451682100.015
larval developmentGO:00021641040.015
Worm
carbohydrate derivative metabolic processGO:19011352170.015
Human Yeast
negative regulation of cell communicationGO:00106482230.015
chaeta developmentGO:0022416970.014
cation transmembrane transportGO:0098655880.014
protein localization to organelleGO:0033365820.014
Yeast
localization of cellGO:00516742570.014
body morphogenesisGO:001017120.014
cellular amine metabolic processGO:0044106120.014
regulation of hemocyte proliferationGO:0035206370.014
immune responseGO:00069552460.014
spindle assemblyGO:0051225800.014
positive regulation of rna metabolic processGO:00512542710.014
regulation of cytoplasmic transportGO:1903649470.014
ameboidal type cell migrationGO:00016671510.014
regulation of response to biotic stimulusGO:0002831630.014
vesicle organizationGO:0016050440.014
Human Yeast
tissue deathGO:00162711020.013
protein prenylationGO:001834230.013
cation transportGO:00068121100.013
Mouse
response to ionizing radiationGO:0010212320.013
agingGO:00075681430.013
regulation of intracellular transportGO:0032386640.013
regulation of protein transportGO:0051223570.013
proteolysisGO:00065081920.013
amine metabolic processGO:0009308120.013
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200100.013
anatomical structure homeostasisGO:0060249970.013
regulation of macroautophagyGO:0016241150.013
multicellular organismal agingGO:00102591400.013
positive regulation of purine nucleotide metabolic processGO:1900544550.013
antimicrobial humoral responseGO:0019730990.013
regulation of phosphorylationGO:00423251470.013
positive regulation of phosphorus metabolic processGO:00105621390.012
protein secretionGO:0009306450.012
ras protein signal transductionGO:0007265880.012
protein kinase b signalingGO:004349110.012
regulation of cellular component biogenesisGO:00440872010.012
positive regulation of cell developmentGO:0010720610.012
macromolecule catabolic processGO:00090571610.012
axon developmentGO:00615642970.012
cellular response to starvationGO:0009267610.012
instar larval developmentGO:0002168550.012
erbb signaling pathwayGO:0038127580.012
translationGO:0006412690.012
negative regulation of signalingGO:00230572190.012
regulation of cellular amine metabolic processGO:003323830.012
regulation of cell shapeGO:00083601130.012
response to organic substanceGO:00100332840.012
Human
dna repairGO:0006281540.012
cell divisionGO:00513012480.012
Human
endomembrane system organizationGO:00102561190.012
Mouse
cellular amino acid metabolic processGO:0006520610.012
cortical actin cytoskeleton organizationGO:0030866240.012
establishment of protein localization to organelleGO:0072594620.011
regulation of secretionGO:0051046440.011
Human
regulation of catabolic processGO:00098941700.011
purine ribonucleoside catabolic processGO:00461301120.011
Human Yeast
protein targeting to nucleusGO:0044744510.011
regulation of cellular response to stressGO:0080135890.011
purine nucleotide metabolic processGO:00061631460.011
Human Yeast
kidney morphogenesisGO:006099330.011
response to light stimulusGO:00094161240.011
positive regulation of phagocytosis engulfmentGO:006010010.011
positive regulation of transportGO:0051050920.011
Human
histone h4 k16 acetylationGO:004398440.011
antimicrobial peptide productionGO:0002775460.011
leg disc morphogenesisGO:0007478800.011
cortical cytoskeleton organizationGO:0030865290.011
positive regulation of rna biosynthetic processGO:19026802660.011
regulation of meiosisGO:004002030.011
epithelial cell developmentGO:00020642740.011
phosphatidylinositol phosphorylationGO:0046854100.011
organonitrogen compound catabolic processGO:19015651280.011
Human Yeast
negative regulation of gene expressionGO:00106293870.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
regulation of establishment of protein localizationGO:0070201610.011
regulation of notch signaling pathwayGO:00085931000.011
defense response to other organismGO:00985422250.011
regulation of transferase activityGO:0051338580.010
positive regulation of response to external stimulusGO:0032103440.010
autophagic cell deathGO:0048102830.010
cellular protein modification processGO:00064644380.010
epithelial cell migrationGO:00106311480.010
guanosine containing compound catabolic processGO:1901069740.010
organelle localizationGO:00516401480.010
positive regulation of intracellular signal transductionGO:19025331160.010
positive regulation of autophagyGO:0010508210.010
neuron projection guidanceGO:00974852410.010

Vps4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.097
disease of anatomical entityDOID:700.097
central nervous system diseaseDOID:33100.019
neurodegenerative diseaseDOID:128900.015
motor neuron diseaseDOID:23100.015
cancerDOID:16200.010
disease of cellular proliferationDOID:1456600.010