IMP: Integrative Multi-species Prediction

Drosophila melanogaster

119 known processes

BRWD3 (Dmel_CG31132)

CG31132 gene product from transcript CG31132-RA

(Aliases: ram,CG6400,anon-WO0118547.620,anon-WO0118547.520,Dmel\CG31132,CG18670,l(3)05842,l(3)s5349,dBRWD3,CG31132)

FLYBASE: FBgn0011785
Entrez: 42898
UniProtKB: Q9VC96

Process Predictions
Disease Predictions

BRWD3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.984	Mouse
mitotic g2 m transition checkpoint	GO:0044818	70	0.971
histone modification	GO:0016570	106	0.969
chromatin organization	GO:0006325	207	0.967
g2 dna damage checkpoint	GO:0031572	69	0.943
positive regulation of transcription dna templated	GO:0045893	266	0.937	Mouse
spermatogenesis	GO:0007283	200	0.916
chromatin silencing	GO:0006342	76	0.907
positive regulation of biosynthetic process	GO:0009891	316	0.901	Mouse
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.893
cellular response to dna damage stimulus	GO:0006974	223	0.852
mitotic dna integrity checkpoint	GO:0044774	75	0.847
negative regulation of cell cycle phase transition	GO:1901988	103	0.816
chromosome organization	GO:0051276	360	0.813
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.798	Mouse
positive regulation of rna biosynthetic process	GO:1902680	266	0.793	Mouse
transcription from rna polymerase ii promoter	GO:0006366	368	0.776	Mouse
response to oxygen containing compound	GO:1901700	200	0.775
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.767
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.750
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.748	Mouse
cell cycle checkpoint	GO:0000075	95	0.734
response to organic cyclic compound	GO:0014070	89	0.719
negative regulation of cellular metabolic process	GO:0031324	382	0.713
multi organism behavior	GO:0051705	175	0.705
mitotic g2 dna damage checkpoint	GO:0007095	69	0.703
chromatin modification	GO:0016568	147	0.701
positive regulation of rna metabolic process	GO:0051254	271	0.697	Mouse
negative regulation of rna biosynthetic process	GO:1902679	240	0.695
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.689	Mouse
mitotic dna damage checkpoint	GO:0044773	74	0.687
negative regulation of transcription dna templated	GO:0045892	237	0.680
protein dna complex subunit organization	GO:0071824	86	0.672
growth	GO:0040007	359	0.665	Mouse
dna integrity checkpoint	GO:0031570	81	0.639
protein complex biogenesis	GO:0070271	201	0.638
negative regulation of gene expression	GO:0010629	387	0.629
positive regulation of cellular biosynthetic process	GO:0031328	316	0.628	Mouse
response to sterol	GO:0036314	34	0.611
covalent chromatin modification	GO:0016569	106	0.607
mitotic cell cycle checkpoint	GO:0007093	88	0.602
macromolecular complex assembly	GO:0065003	256	0.592
regulation of cell cycle	GO:0051726	291	0.582
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.578
male gamete generation	GO:0048232	201	0.568
appendage morphogenesis	GO:0035107	397	0.543
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.534
positive regulation of gene expression	GO:0010628	290	0.475	Mouse
cellular protein modification process	GO:0006464	438	0.471	Mouse
embryo development ending in birth or egg hatching	GO:0009792	152	0.469
positive regulation of macromolecule metabolic process	GO:0010604	405	0.465	Mouse
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.427
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.413	Mouse
multicellular organismal reproductive behavior	GO:0033057	110	0.403
negative regulation of rna metabolic process	GO:0051253	251	0.402
histolysis	GO:0007559	102	0.402
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.391
sex differentiation	GO:0007548	81	0.380
cellular catabolic process	GO:0044248	372	0.372
response to abiotic stimulus	GO:0009628	341	0.366
establishment of organelle localization	GO:0051656	122	0.345
dna damage checkpoint	GO:0000077	78	0.343
induction of programmed cell death by hormones	GO:0035081	12	0.342
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.338
single organism intracellular transport	GO:1902582	207	0.334	Mouse
regulation of organelle organization	GO:0033043	196	0.328	Mouse
cell proliferation	GO:0008283	299	0.323	Mouse
multi organism reproductive behavior	GO:0044705	121	0.320
organelle assembly	GO:0070925	198	0.320
organic substance catabolic process	GO:1901575	308	0.306
negative regulation of cellular biosynthetic process	GO:0031327	277	0.299
protein modification process	GO:0036211	438	0.293	Mouse
neurological system process	GO:0050877	358	0.291
wnt signaling pathway	GO:0016055	98	0.288
nuclear division	GO:0000280	332	0.278	Mouse
oviposition	GO:0018991	19	0.269
protein complex assembly	GO:0006461	200	0.267
salivary gland histolysis	GO:0035070	88	0.261
cellular macromolecular complex assembly	GO:0034622	153	0.258
response to alcohol	GO:0097305	95	0.253
tissue death	GO:0016271	102	0.248
chromatin remodeling	GO:0006338	72	0.247
cellular response to chemical stimulus	GO:0070887	199	0.245	Mouse
dna metabolic process	GO:0006259	227	0.238
catabolic process	GO:0009056	409	0.237
cellular component assembly involved in morphogenesis	GO:0010927	151	0.233
stem cell maintenance	GO:0019827	67	0.229
negative regulation of biosynthetic process	GO:0009890	277	0.229
nucleosome organization	GO:0034728	59	0.226
negative regulation of cell cycle process	GO:0010948	109	0.226
cellular protein catabolic process	GO:0044257	83	0.226
rna processing	GO:0006396	147	0.223
cellular macromolecule catabolic process	GO:0044265	136	0.212
regulation of cell cycle phase transition	GO:1901987	130	0.207
negative regulation of signaling	GO:0023057	219	0.204
regulation of cell proliferation	GO:0042127	163	0.201	Mouse
cell cycle phase transition	GO:0044770	140	0.199
protein dna complex assembly	GO:0065004	63	0.196
post embryonic appendage morphogenesis	GO:0035120	385	0.196
regulation of cell cycle process	GO:0010564	181	0.194
regulation of multicellular organismal development	GO:2000026	414	0.193
protein localization	GO:0008104	284	0.183	Mouse
dna packaging	GO:0006323	91	0.178
multi multicellular organism process	GO:0044706	123	0.177
reproductive behavior	GO:0019098	122	0.173
phosphorylation	GO:0016310	294	0.171	Mouse
positive regulation of cellular protein metabolic process	GO:0032270	118	0.170	Mouse
chromatin assembly	GO:0031497	48	0.167
internal protein amino acid acetylation	GO:0006475	38	0.163
cellular response to oxygen containing compound	GO:1901701	79	0.155	Mouse
development of primary sexual characteristics	GO:0045137	50	0.153
negative regulation of gene expression epigenetic	GO:0045814	77	0.152
developmental programmed cell death	GO:0010623	138	0.151
muscle structure development	GO:0061061	224	0.148
dna templated transcription initiation	GO:0006352	25	0.146
actin filament based process	GO:0030029	220	0.144
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.143
hematopoietic or lymphoid organ development	GO:0048534	57	0.142
cell motility	GO:0048870	251	0.141
dna repair	GO:0006281	54	0.140
positive regulation of developmental process	GO:0051094	143	0.140
regulation of gene expression epigenetic	GO:0040029	128	0.139
imaginal disc derived appendage development	GO:0048737	399	0.139
nucleosome mobilization	GO:0042766	9	0.138
negative regulation of cell cycle	GO:0045786	116	0.136
death	GO:0016265	284	0.134
immune system process	GO:0002376	347	0.132
histone acetylation	GO:0016573	38	0.132
autophagic cell death	GO:0048102	83	0.126
cellular ketone metabolic process	GO:0042180	24	0.124
positive regulation of signal transduction	GO:0009967	223	0.118
salivary gland development	GO:0007431	162	0.118
negative regulation of cell differentiation	GO:0045596	143	0.117
regulation of cell differentiation	GO:0045595	302	0.115
oxoacid metabolic process	GO:0043436	103	0.114
exocrine system development	GO:0035272	162	0.113
regulation of cellular response to hypoxia	GO:1900037	3	0.111
negative regulation of mitotic cell cycle	GO:0045930	109	0.110
meiotic cell cycle process	GO:1903046	132	0.110
mitotic spindle organization	GO:0007052	220	0.110
dna conformation change	GO:0071103	105	0.110
positive regulation of signaling	GO:0023056	243	0.109
macromolecule catabolic process	GO:0009057	161	0.109
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.107
gland morphogenesis	GO:0022612	145	0.107
ecdysone mediated induction of salivary gland cell autophagic cell death	GO:0035072	12	0.104
immune system development	GO:0002520	57	0.104
atp dependent chromatin remodeling	GO:0043044	22	0.104
amine metabolic process	GO:0009308	12	0.103
response to ecdysone	GO:0035075	34	0.103
positive regulation of response to stimulus	GO:0048584	323	0.097
forebrain development	GO:0030900	2	0.095
cellular response to organic substance	GO:0071310	132	0.094	Mouse
spermatid differentiation	GO:0048515	114	0.093
imaginal disc derived leg morphogenesis	GO:0007480	80	0.093
regulation of neurogenesis	GO:0050767	158	0.093
gene silencing	GO:0016458	138	0.091
regulation of cellular ketone metabolic process	GO:0010565	3	0.091
response to organonitrogen compound	GO:0010243	75	0.090	Mouse
tube development	GO:0035295	244	0.088
cellular protein complex assembly	GO:0043623	71	0.088
reproductive structure development	GO:0048608	74	0.085
body morphogenesis	GO:0010171	2	0.085
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.085
salivary gland cell autophagic cell death	GO:0035071	83	0.084
localization of cell	GO:0051674	257	0.083
regulation of mrna metabolic process	GO:1903311	72	0.082
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.081
larval midgut histolysis	GO:0035069	22	0.081
meiotic cell cycle	GO:0051321	171	0.079
transcription initiation from rna polymerase ii promoter	GO:0006367	25	0.079
negative regulation of multicellular organismal process	GO:0051241	142	0.079
peptidyl lysine acetylation	GO:0018394	39	0.079
single organism biosynthetic process	GO:0044711	206	0.075
response to hormone	GO:0009725	45	0.074	Mouse
rna polymerase ii transcriptional preinitiation complex assembly	GO:0051123	20	0.074
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.073
appendage development	GO:0048736	401	0.073
organonitrogen compound metabolic process	GO:1901564	318	0.072
regulation of cellular protein metabolic process	GO:0032268	243	0.071	Mouse
regulation of establishment of protein localization	GO:0070201	61	0.071
peptidyl lysine modification	GO:0018205	57	0.071
regulation of cellular amine metabolic process	GO:0033238	3	0.069
vesicle mediated transport	GO:0016192	381	0.069
regulation of rna splicing	GO:0043484	69	0.068
positive regulation of transport	GO:0051050	92	0.068
regulation of cell development	GO:0060284	215	0.067
intracellular signal transduction	GO:0035556	300	0.066
mitotic cell cycle phase transition	GO:0044772	138	0.066
protein acylation	GO:0043543	42	0.066
ncrna metabolic process	GO:0034660	43	0.066
peptidyl amino acid modification	GO:0018193	105	0.065	Mouse
organelle localization	GO:0051640	148	0.065
protein acetylation	GO:0006473	39	0.064
chromatin assembly or disassembly	GO:0006333	52	0.063
salivary gland morphogenesis	GO:0007435	145	0.063
regulation of protein localization	GO:0032880	76	0.062
response to endogenous stimulus	GO:0009719	119	0.061	Mouse
atp metabolic process	GO:0046034	49	0.060
regionalization	GO:0003002	416	0.060
dna templated transcriptional preinitiation complex assembly	GO:0070897	20	0.059
reproductive system development	GO:0061458	74	0.058
meiosis i	GO:0007127	59	0.058
gonad development	GO:0008406	50	0.058
protein modification by small protein conjugation or removal	GO:0070647	106	0.057
positive regulation of protein metabolic process	GO:0051247	128	0.056	Mouse
dna templated transcription elongation	GO:0006354	18	0.055
small molecule metabolic process	GO:0044281	305	0.055
gland development	GO:0048732	191	0.055
locomotory behavior	GO:0007626	176	0.054
regulation of growth	GO:0040008	233	0.054	Mouse
regulation of immune system process	GO:0002682	176	0.053
modification dependent macromolecule catabolic process	GO:0043632	79	0.053
response to nitrogen compound	GO:1901698	90	0.053	Mouse
glycosyl compound metabolic process	GO:1901657	127	0.052
meiotic nuclear division	GO:0007126	151	0.052
negative regulation of organelle organization	GO:0010639	56	0.052
regulation of cellular amino acid metabolic process	GO:0006521	0	0.052
carboxylic acid metabolic process	GO:0019752	92	0.052
leg disc morphogenesis	GO:0007478	80	0.052
wing disc morphogenesis	GO:0007472	344	0.051
rna splicing via transesterification reactions	GO:0000375	73	0.051
nuclear pore organization	GO:0006999	1	0.051
response to decreased oxygen levels	GO:0036293	58	0.050
ubiquitin dependent protein catabolic process	GO:0006511	78	0.050
cellular nitrogen compound catabolic process	GO:0044270	165	0.049
regulation of mrna processing	GO:0050684	71	0.049
regulation of cellular catabolic process	GO:0031329	157	0.048
regulation of intracellular signal transduction	GO:1902531	236	0.048
dendrite morphogenesis	GO:0048813	199	0.047
organic substance transport	GO:0071702	257	0.047	Mouse
regulation of developmental growth	GO:0048638	174	0.047
leg disc development	GO:0035218	92	0.046
respiratory system development	GO:0060541	213	0.046
regulation of catabolic process	GO:0009894	170	0.046
induction of programmed cell death	GO:0012502	12	0.045
pharynx development	GO:0060465	1	0.045
negative regulation of cell development	GO:0010721	62	0.045
single organism behavior	GO:0044708	391	0.045
tube morphogenesis	GO:0035239	191	0.044
cell migration	GO:0016477	238	0.044
larval development	GO:0002164	104	0.043
response to ketone	GO:1901654	34	0.042
cellular macromolecule localization	GO:0070727	220	0.042	Mouse
cellular response to peptide	GO:1901653	28	0.042	Mouse
endocytosis	GO:0006897	310	0.040
positive regulation of nucleocytoplasmic transport	GO:0046824	24	0.040
regulation of localization	GO:0032879	275	0.040
nucleocytoplasmic transport	GO:0006913	72	0.039	Mouse
aromatic compound catabolic process	GO:0019439	166	0.039
mrna splicing via spliceosome	GO:0000398	73	0.038
regulation of cellular localization	GO:0060341	136	0.038
spindle organization	GO:0007051	253	0.038
regulation of nervous system development	GO:0051960	248	0.037
digestive tract development	GO:0048565	149	0.037
regulation of cellular response to stress	GO:0080135	89	0.036
chromosome condensation	GO:0030261	41	0.036
negative regulation of developmental process	GO:0051093	201	0.036
establishment of rna localization	GO:0051236	47	0.036
telencephalon development	GO:0021537	2	0.035
regulation of chromatin modification	GO:1903308	28	0.035
negative regulation of cellular component organization	GO:0051129	108	0.035
dna biosynthetic process	GO:0071897	24	0.035
cellular response to organic cyclic compound	GO:0071407	32	0.035
histone h4 k16 acetylation	GO:0043984	4	0.034
positive regulation of cellular component organization	GO:0051130	156	0.034	Mouse
organic cyclic compound catabolic process	GO:1901361	168	0.034
regulation of cytoskeleton organization	GO:0051493	89	0.034
regulation of programmed cell death	GO:0043067	152	0.034
protein catabolic process	GO:0030163	101	0.033
rna splicing	GO:0008380	83	0.033
negative regulation of intracellular signal transduction	GO:1902532	57	0.033
establishment of protein localization	GO:0045184	163	0.033	Mouse
positive regulation of cell communication	GO:0010647	250	0.032
regulation of mrna splicing via spliceosome	GO:0048024	64	0.032
nucleobase containing compound catabolic process	GO:0034655	165	0.031
cell division	GO:0051301	248	0.031	Mouse
heterocycle catabolic process	GO:0046700	166	0.031
cytoplasmic transport	GO:0016482	130	0.031	Mouse
nuclear transcribed mrna catabolic process nonsense mediated decay	GO:0000184	8	0.031
regulation of protein metabolic process	GO:0051246	256	0.031	Mouse
small gtpase mediated signal transduction	GO:0007264	88	0.030
protein ubiquitination	GO:0016567	70	0.030
cellular amine metabolic process	GO:0044106	12	0.029
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.029
histone methylation	GO:0016571	40	0.029
regulation of response to stress	GO:0080134	200	0.029
regulation of phosphate metabolic process	GO:0019220	210	0.028	Mouse
histone h3 acetylation	GO:0043966	11	0.028
histone ubiquitination	GO:0016574	4	0.028
gene silencing by rna	GO:0031047	57	0.028
regulation of protein catabolic process	GO:0042176	55	0.028
negative regulation of cell communication	GO:0010648	223	0.027
regulation of molecular function	GO:0065009	217	0.027
positive regulation of erk1 and erk2 cascade	GO:0070374	36	0.027
nitrogen compound transport	GO:0071705	85	0.027
double strand break repair	GO:0006302	26	0.026
programmed cell death	GO:0012501	257	0.026
induction of programmed cell death by ecdysone	GO:0035078	12	0.026
rna catabolic process	GO:0006401	37	0.026
receptor mediated endocytosis	GO:0006898	21	0.026
ras protein signal transduction	GO:0007265	88	0.026
negative regulation of neurogenesis	GO:0050768	53	0.026
response to organic substance	GO:0010033	284	0.026
cellular amino acid metabolic process	GO:0006520	61	0.026
regulation of gene silencing	GO:0060968	63	0.026
establishment of localization in cell	GO:0051649	402	0.026	Mouse
autophagy	GO:0006914	108	0.025
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.025
eye development	GO:0001654	323	0.025
actin cytoskeleton organization	GO:0030036	206	0.025
response to external biotic stimulus	GO:0043207	293	0.025
protein transport	GO:0015031	155	0.024	Mouse
regulation of phosphorylation	GO:0042325	147	0.024	Mouse
regulation of dna templated transcription elongation	GO:0032784	17	0.024
chromosome segregation	GO:0007059	157	0.024
regulation of protein transport	GO:0051223	57	0.023
g1 s transition of mitotic cell cycle	GO:0000082	31	0.023
regulation of cellular component biogenesis	GO:0044087	201	0.023
positive regulation of catabolic process	GO:0009896	105	0.022
regulation of meiosis	GO:0040020	3	0.022
cellular response to organonitrogen compound	GO:0071417	36	0.022	Mouse
cell death	GO:0008219	279	0.022
regulation of catalytic activity	GO:0050790	185	0.022
regulation of chromosome organization	GO:0033044	64	0.022
mrna catabolic process	GO:0006402	33	0.022
protein modification by small protein conjugation	GO:0032446	79	0.022
genitalia development	GO:0048806	26	0.021
posttranscriptional gene silencing by rna	GO:0035194	45	0.021
posttranscriptional gene silencing	GO:0016441	46	0.021
embryonic development via the syncytial blastoderm	GO:0001700	148	0.021
positive regulation of developmental growth	GO:0048639	62	0.021
rna localization	GO:0006403	115	0.021
cellular response to nitrogen compound	GO:1901699	51	0.021	Mouse
protein alkylation	GO:0008213	43	0.021
regulation of protein complex assembly	GO:0043254	42	0.021
regulation of actin cytoskeleton organization	GO:0032956	42	0.020
pupal development	GO:0035209	11	0.020
mrna processing	GO:0006397	104	0.020
nucleosome positioning	GO:0016584	3	0.020
regulation of g1 s transition of mitotic cell cycle	GO:2000045	23	0.020
methylation	GO:0032259	47	0.020
learning	GO:0007612	75	0.020
response to other organism	GO:0051707	293	0.020
histone lysine methylation	GO:0034968	32	0.020
organelle fission	GO:0048285	340	0.020	Mouse
dephosphorylation	GO:0016311	51	0.020
response to peptide hormone	GO:0043434	29	0.019	Mouse
internal peptidyl lysine acetylation	GO:0018393	38	0.019
nucleoside phosphate metabolic process	GO:0006753	162	0.019
positive regulation of cellular catabolic process	GO:0031331	95	0.019
ribonucleoprotein complex biogenesis	GO:0022613	31	0.019
heart contraction	GO:0060047	26	0.019
actin filament organization	GO:0007015	126	0.019
alternative mrna splicing via spliceosome	GO:0000380	60	0.018
rhythmic process	GO:0048511	106	0.018
regulation of protein export from nucleus	GO:0046825	3	0.018
positive regulation of multicellular organismal process	GO:0051240	143	0.018
border follicle cell migration	GO:0007298	113	0.018
developmental maturation	GO:0021700	172	0.018
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.018	Mouse
negative regulation of chromosome segregation	GO:0051985	14	0.018
mating behavior	GO:0007617	106	0.018
single organism cellular localization	GO:1902580	180	0.017	Mouse
centrosome organization	GO:0051297	163	0.017
protein complex disassembly	GO:0043241	36	0.017
positive regulation of intracellular signal transduction	GO:1902533	116	0.017
dendrite development	GO:0016358	204	0.017
eye antennal disc development	GO:0035214	60	0.017
cellular response to endogenous stimulus	GO:0071495	80	0.017	Mouse
hematopoietic progenitor cell differentiation	GO:0002244	1	0.017
signal transduction in response to dna damage	GO:0042770	3	0.017
positive regulation of purine nucleotide catabolic process	GO:0033123	46	0.017
mrna metabolic process	GO:0016071	124	0.017
positive regulation of cellular amine metabolic process	GO:0033240	0	0.016
cellular response to oxygen levels	GO:0071453	30	0.016
protein modification by small protein removal	GO:0070646	28	0.016
positive regulation of organelle organization	GO:0010638	65	0.016	Mouse
histone h4 acetylation	GO:0043967	13	0.016
response to oxygen levels	GO:0070482	59	0.016
regulation of wnt signaling pathway	GO:0030111	68	0.016
stem cell development	GO:0048864	79	0.016
negative regulation of cell proliferation	GO:0008285	69	0.016
positive regulation of cell cycle	GO:0045787	43	0.016	Mouse
response to hypoxia	GO:0001666	53	0.016
modification dependent protein catabolic process	GO:0019941	78	0.015
regulation of sister chromatid cohesion	GO:0007063	2	0.015
microtubule organizing center organization	GO:0031023	168	0.015
mitotic sister chromatid segregation	GO:0000070	87	0.015
histone lysine demethylation	GO:0070076	6	0.015
rna transport	GO:0050658	46	0.015
chemosensory behavior	GO:0007635	106	0.015
nucleobase containing compound transport	GO:0015931	56	0.015
sister chromatid segregation	GO:0000819	92	0.015
regulation of ras protein signal transduction	GO:0046578	93	0.014
regulation of cellular protein catabolic process	GO:1903362	44	0.014
multicellular organism growth	GO:0035264	46	0.014
positive regulation of cell cycle process	GO:0090068	28	0.014	Mouse
hemopoiesis	GO:0030097	46	0.014
cellular protein localization	GO:0034613	160	0.014	Mouse
muscle organ development	GO:0007517	127	0.014
response to lipid	GO:0033993	38	0.014
regulation of cytoplasmic transport	GO:1903649	47	0.014
negative regulation of nervous system development	GO:0051961	92	0.014
regulation of mitotic cell cycle	GO:0007346	190	0.014
positive regulation of growth	GO:0045927	75	0.014
regulation of protein complex disassembly	GO:0043244	29	0.014
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.014
regulation of transport	GO:0051049	181	0.013
nuclear import	GO:0051170	51	0.013	Mouse
carbohydrate derivative metabolic process	GO:1901135	217	0.013
signal transduction by phosphorylation	GO:0023014	107	0.013
positive regulation of intracellular transport	GO:0032388	42	0.013
intracellular transport	GO:0046907	228	0.013	Mouse
positive regulation of molecular function	GO:0044093	136	0.013
dorsal ventral pattern formation imaginal disc	GO:0007450	51	0.013
ncrna processing	GO:0034470	30	0.013
hindbrain development	GO:0030902	2	0.013
protein methylation	GO:0006479	43	0.013
positive regulation of protein import into nucleus	GO:0042307	21	0.013
regulation of intracellular transport	GO:0032386	64	0.013
ribonucleoside metabolic process	GO:0009119	127	0.013
glycoprotein biosynthetic process	GO:0009101	41	0.012
regulation of multi organism process	GO:0043900	131	0.012
heart process	GO:0003015	37	0.012
positive regulation of protein transport	GO:0051222	37	0.012
morphogenesis of an epithelium	GO:0002009	276	0.012
anterior posterior pattern specification	GO:0009952	136	0.012
anterior posterior axis specification	GO:0009948	109	0.012
chromosome localization	GO:0050000	20	0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.012
positive regulation of cell proliferation	GO:0008284	47	0.012	Mouse
purine ribonucleoside catabolic process	GO:0046130	112	0.012
striated muscle cell development	GO:0055002	50	0.012
gene silencing by mirna	GO:0035195	22	0.012
embryonic pattern specification	GO:0009880	174	0.012
proteolysis	GO:0006508	192	0.012
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.012
eggshell chorion gene amplification	GO:0007307	9	0.012
single organism catabolic process	GO:0044712	228	0.012
rna interference	GO:0016246	27	0.012
nucleotide metabolic process	GO:0009117	161	0.011
regulation of erk1 and erk2 cascade	GO:0070372	39	0.011
cell fate specification	GO:0001708	71	0.011
negative regulation of signal transduction	GO:0009968	206	0.011
defense response to other organism	GO:0098542	225	0.011
antimicrobial humoral response	GO:0019730	99	0.011
protein deubiquitination	GO:0016579	17	0.011
positive regulation of mapk cascade	GO:0043410	63	0.011
oocyte differentiation	GO:0009994	145	0.011
taxis	GO:0042330	304	0.011
compound eye photoreceptor fate commitment	GO:0001752	36	0.011
spliceosomal complex assembly	GO:0000245	1	0.011
response to peptide	GO:1901652	29	0.011	Mouse
icosanoid biosynthetic process	GO:0046456	1	0.011
regulation of multicellular organism growth	GO:0040014	40	0.011
camera type eye development	GO:0043010	4	0.011
regulation of stem cell proliferation	GO:0072091	40	0.011
organic acid metabolic process	GO:0006082	103	0.011
positive regulation of small gtpase mediated signal transduction	GO:0051057	43	0.011
response to radiation	GO:0009314	155	0.011
protein localization to organelle	GO:0033365	82	0.011	Mouse
histone h2a acetylation	GO:0043968	1	0.011
mating	GO:0007618	120	0.011
nucleoside triphosphate metabolic process	GO:0009141	120	0.011
cellular response to peptide hormone stimulus	GO:0071375	28	0.011	Mouse
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	44	0.011
proteasomal protein catabolic process	GO:0010498	59	0.011
regulation of transcription elongation from rna polymerase ii promoter	GO:0034243	15	0.011
cognition	GO:0050890	141	0.011
regulation of apoptotic process	GO:0042981	130	0.011	Mouse
nuclear transport	GO:0051169	72	0.011	Mouse
immune response	GO:0006955	246	0.011
intracellular steroid hormone receptor signaling pathway	GO:0030518	12	0.010
morphogenesis of a polarized epithelium	GO:0001738	93	0.010
nucleic acid transport	GO:0050657	46	0.010
histone h3 k9 acetylation	GO:0043970	3	0.010
regulation of anatomical structure morphogenesis	GO:0022603	242	0.010	Human
maintenance of location	GO:0051235	73	0.010
carbohydrate derivative catabolic process	GO:1901136	118	0.010
ribonucleotide metabolic process	GO:0009259	145	0.010
imaginal disc growth	GO:0007446	37	0.010
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.010
regulation of chromatin silencing	GO:0031935	36	0.010
regulation of intracellular protein transport	GO:0033157	46	0.010
epithelial cell differentiation	GO:0030855	322	0.010

BRWD3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.099
cancer	DOID:162	0.077
organ system cancer	DOID:0050686	0.071
disease of anatomical entity	DOID:7	0.018
nervous system disease	DOID:863	0.017

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