Drosophila melanogaster

124 known processes

Dscam (Dmel_CG17800)

Down syndrome cell adhesion molecule

(Aliases: Dscam1,Dmel\CG17800,CT39257,FBgn0033159,43Bc,p270,Neu1,l(2)43Bc,dscam,DScam,dScam,DSCAM,CG17800,l(2)05518)

Dscam biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
axon developmentGO:00615642970.999
dendrite developmentGO:00163582040.992
dendrite morphogenesisGO:00488131990.992
regulation of axon guidanceGO:1902667100.987
Human Mouse
axon guidanceGO:00074112330.984
axonogenesisGO:00074092900.983
mushroom body developmentGO:0016319700.981
chemotaxisGO:00069352490.979
brain developmentGO:00074201200.977
regulation of axon extension involved in axon guidanceGO:004884140.976
Human Mouse
central nervous system developmentGO:00074172010.970
neuron projection guidanceGO:00974852410.968
taxisGO:00423303040.967
dendrite guidanceGO:0070983210.956
regulation of cell developmentGO:00602842150.903
muscle structure developmentGO:00610612240.880
positive regulation of cell projection organizationGO:0031346290.858
Human Mouse
head developmentGO:00603221350.839
axon extension involved in axon guidanceGO:0048846100.839
regulation of dendrite morphogenesisGO:0048814280.816
regulation of dendrite developmentGO:0050773370.764
regulation of chemotaxisGO:0050920120.763
Human Mouse
neuron recognitionGO:00080381010.720
activation of cysteine type endopeptidase activityGO:0097202170.719
retinal ganglion cell axon guidanceGO:0031290120.705
regulation of neuron projection developmentGO:0010975690.705
positive regulation of axonogenesisGO:005077220.683
Human Mouse
negative regulation of signalingGO:00230572190.682
spindle elongationGO:0051231830.673
regulation of cell projection organizationGO:0031344920.662
cell motilityGO:00488702510.660
Zebrafish
axon extensionGO:0048675320.648
regulation of localizationGO:00328792750.637
Human Mouse
ameboidal type cell migrationGO:00016671510.623
Zebrafish
dorsal ventral axon guidanceGO:003356320.595
neuron projection extensionGO:1990138320.561
axon midline choice point recognitionGO:0016199260.550
epithelial cell developmentGO:00020642740.540
regulation of cell differentiationGO:00455953020.537
regulation of cell sizeGO:0008361630.529
Human Mouse
positive regulation of cell morphogenesis involved in differentiationGO:0010770120.519
Human Mouse
positive regulation of developmental processGO:00510941430.476
Human Mouse
photoreceptor cell axon guidanceGO:0072499230.469
positive regulation of dendrite morphogenesisGO:005077590.466
positive regulation of neuron differentiationGO:0045666260.465
Human Mouse
regulation of cysteine type endopeptidase activityGO:2000116270.427
regulation of cellular component sizeGO:0032535980.406
Human Mouse
positive regulation of developmental growthGO:0048639620.401
Human Mouse
multi organism behaviorGO:00517051750.401
regulation of cell morphogenesisGO:00226041630.401
exocrine system developmentGO:00352721620.381
positive regulation of cell growthGO:0030307190.378
Human Mouse
positive regulation of axon extensionGO:004577320.371
Human Mouse
axon choice point recognitionGO:0016198260.364
neuron remodelingGO:0016322290.355
eye developmentGO:00016543230.346
Mouse
regulation of cellular component biogenesisGO:00440872010.342
cell migrationGO:00164772380.341
Zebrafish
axon regenerationGO:003110380.327
response to alcoholGO:0097305950.318
regulation of multicellular organismal developmentGO:20000264140.308
regulation of synapse structure and activityGO:00508031280.305
enzyme linked receptor protein signaling pathwayGO:00071671790.297
cell recognitionGO:00080371020.294
positive regulation of neuron projection developmentGO:0010976140.293
Human Mouse
embryo development ending in birth or egg hatchingGO:00097921520.289
Human Worm
locomotory behaviorGO:00076261760.286
Mouse
gland developmentGO:00487321910.279
positive regulation of neurogenesisGO:0050769410.271
Human Mouse
positive regulation of locomotionGO:004001780.261
Human Mouse
negative regulation of cell communicationGO:00106482230.257
regulation of developmental growthGO:00486381740.256
Human Mouse
neurological system processGO:00508773580.255
central nervous system projection neuron axonogenesisGO:002195260.254
cell growthGO:00160491080.245
negative regulation of signal transductionGO:00099682060.241
regulation of anatomical structure sizeGO:00900661630.233
Human Mouse
mitotic spindle elongationGO:0000022810.231
establishment of localization in cellGO:00516494020.228
cellular macromolecular complex assemblyGO:00346221530.222
negative regulation of gene expressionGO:00106293870.212
positive regulation of cellular component organizationGO:00511301560.210
Human Mouse
regulation of nervous system developmentGO:00519602480.201
regulation of neuron differentiationGO:00456641030.198
negative regulation of response to stimulusGO:00485852580.197
regulation of growthGO:00400082330.193
Human Mouse
positive regulation of macromolecule biosynthetic processGO:00105572830.186
homeostatic processGO:00425921990.183
growthGO:00400073590.179
central complex developmentGO:004803690.177
regulation of neurogenesisGO:00507671580.175
regulation of cell morphogenesis involved in differentiationGO:0010769610.174
synapse assemblyGO:00074161430.174
synapse organizationGO:00508081960.173
developmental growthGO:00485892800.172
response to organic substanceGO:00100332840.170
negative regulation of nitrogen compound metabolic processGO:00511722650.167
negative regulation of multicellular organismal processGO:00512411420.163
gland morphogenesisGO:00226121450.159
regulation of behaviorGO:0050795750.158
Human Mouse
tissue morphogenesisGO:00487292970.152
Mouse
imaginal disc derived appendage morphogenesisGO:00351143950.149
regulation of cell cycleGO:00517262910.147
olfactory bulb axon guidanceGO:007167830.144
appendage developmentGO:00487364010.143
mitotic spindle organizationGO:00070522200.139
positive regulation of cell developmentGO:0010720610.137
Human Mouse
developmental cell growthGO:0048588520.136
developmental growth involved in morphogenesisGO:0060560650.130
localization of cellGO:00516742570.127
Zebrafish
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.124
regulation of axon extensionGO:003051680.124
Human Mouse
positive regulation of axon guidanceGO:190266910.122
Human Mouse
ventral cord developmentGO:0007419160.121
positive regulation of cell motilityGO:200014730.120
positive regulation of cell migrationGO:003033520.113
stem cell developmentGO:0048864790.111
axonal fasciculationGO:0007413120.111
lamellipodium organizationGO:0097581210.110
single organism behaviorGO:00447083910.110
appendage morphogenesisGO:00351073970.104
actin filament based processGO:00300292200.103
embryonic development via the syncytial blastodermGO:00017001480.102
regulation of peptidase activityGO:0052547390.102
regulation of synapse organizationGO:00508071100.100
neuron projection extension involved in neuron projection guidanceGO:1902284100.099
single organism carbohydrate metabolic processGO:0044723720.099
tissue migrationGO:00901301550.098
positive regulation of macromolecule metabolic processGO:00106044050.097
cellular response to ketoneGO:1901655170.097
positive regulation of multicellular organismal processGO:00512401430.094
Human Mouse
positive regulation of nervous system developmentGO:0051962690.094
Human Mouse
positive regulation of gene expressionGO:00106282900.094
neuromuscular junction developmentGO:00075281490.093
carbohydrate metabolic processGO:0005975820.092
regulation of epithelial cell migration open tracheal systemGO:2000274110.092
imaginal disc derived wing morphogenesisGO:00074763370.092
motor neuron axon guidanceGO:0008045580.092
negative regulation of cellular component organizationGO:00511291080.091
salivary gland developmentGO:00074311620.088
negative regulation of neuroblast proliferationGO:0007406270.088
forebrain developmentGO:003090020.086
negative regulation of cell differentiationGO:00455961430.086
maintenance of locationGO:0051235730.083
morphogenesis of an epitheliumGO:00020092760.082
negative regulation of axon extensionGO:003051730.082
regulation of photoreceptor cell axon guidanceGO:200028950.081
actomyosin structure organizationGO:0031032560.080
phosphorylationGO:00163102940.079
Human
protein complex assemblyGO:00064612000.079
apoptotic processGO:00069151590.078
cellular nitrogen compound catabolic processGO:00442701650.077
body morphogenesisGO:001017120.077
neuron maturationGO:0042551310.076
intracellular transportGO:00469072280.076
negative regulation of synapse assemblyGO:0051964390.074
cellular response to chemical stimulusGO:00708871990.073
regulation of protein complex assemblyGO:0043254420.072
positive regulation of cellular component biogenesisGO:0044089800.070
digestive tract morphogenesisGO:00485461270.070
Zebrafish
synaptic growth at neuromuscular junctionGO:00511241190.070
negative regulation of cellular metabolic processGO:00313243820.069
salivary gland boundary specificationGO:000743280.068
negative regulation of developmental processGO:00510932010.065
regionalizationGO:00030024160.064
vesicle mediated transportGO:00161923810.062
regulation of axonogenesisGO:0050770320.062
positive regulation of cellular biosynthetic processGO:00313283160.060
negative regulation of nervous system developmentGO:0051961920.060
regulation of proteolysisGO:0030162870.060
organelle assemblyGO:00709251980.058
cation transportGO:00068121100.056
cellular response to organic cyclic compoundGO:0071407320.055
negative regulation of growthGO:0045926840.055
convergent extensionGO:006002620.054
carbohydrate derivative metabolic processGO:19011352170.054
chemical homeostasisGO:0048878920.052
organophosphate metabolic processGO:00196371950.051
proteolysisGO:00065081920.050
cellular response to organic substanceGO:00713101320.049
macromolecular complex assemblyGO:00650032560.048
regulation of synapse assemblyGO:0051963940.047
neural precursor cell proliferationGO:0061351750.046
actin cytoskeleton organizationGO:00300362060.045
negative regulation of biosynthetic processGO:00098902770.045
regulation of phosphatase activityGO:001092130.045
endocytosisGO:00068973100.045
inter male aggressive behaviorGO:0002121600.045
cell migration involved in gastrulationGO:004207490.045
Zebrafish
collateral sproutingGO:004866830.045
regulation of microtubule based processGO:0032886490.044
transcription from rna polymerase ii promoterGO:00063663680.044
post embryonic appendage morphogenesisGO:00351203850.044
single organism cell adhesionGO:0098602470.044
regulation of anatomical structure morphogenesisGO:00226032420.043
small molecule metabolic processGO:00442813050.042
cellular response to oxygen containing compoundGO:1901701790.042
semaphorin plexin signaling pathwayGO:007152640.042
response to axon injuryGO:0048678120.041
columnar cuboidal epithelial cell differentiationGO:00020652560.040
ovarian follicle cell developmentGO:00307072480.040
negative regulation of cell developmentGO:0010721620.040
small gtpase mediated signal transductionGO:0007264880.040
imaginal disc derived appendage developmentGO:00487373990.039
regulation of protein metabolic processGO:00512462560.039
eye morphogenesisGO:00485922600.039
Mouse
cellular component assembly involved in morphogenesisGO:00109271510.039
deathGO:00162652840.039
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.039
male gamete generationGO:00482322010.038
establishment of proximal distal cell polarityGO:002260640.038
sex differentiationGO:0007548810.038
regulation of synapse structural plasticityGO:005182330.038
regulation of cellular component movementGO:0051270420.038
Human Mouse
tube morphogenesisGO:00352391910.037
Zebrafish
formation of organ boundaryGO:0010160300.037
cell proliferationGO:00082832990.037
ras protein signal transductionGO:0007265880.036
regulation of microtubule cytoskeleton organizationGO:0070507410.036
protein polymerizationGO:0051258420.035
lamellipodium assemblyGO:0030032210.035
gene silencing by rnaGO:0031047570.034
single organism catabolic processGO:00447122280.033
regulation of small gtpase mediated signal transductionGO:0051056930.033
negative regulation of neurogenesisGO:0050768530.033
negative regulation of macromolecule biosynthetic processGO:00105582700.032
regulation of endopeptidase activityGO:0052548360.032
energy derivation by oxidation of organic compoundsGO:0015980320.032
ovarian follicle cell migrationGO:00072971210.031
rho protein signal transductionGO:0007266140.031
muscle attachmentGO:0016203360.031
columnar cuboidal epithelial cell developmentGO:00020662490.030
positive regulation of growthGO:0045927750.029
Human Mouse
secretion by cellGO:00329401010.029
neuron projection regenerationGO:003110280.029
tube developmentGO:00352952440.029
Zebrafish
positive regulation of proteolysisGO:0045862520.028
imaginal disc derived wing hair site selectionGO:003532040.028
regulation of tube architecture open tracheal systemGO:0035152680.028
intracellular signal transductionGO:00355563000.028
ribonucleoside catabolic processGO:00424541120.027
substrate dependent cell migrationGO:000692930.027
neuroblast proliferationGO:0007405740.027
protein complex biogenesisGO:00702712010.027
glycosyl compound catabolic processGO:19016581120.026
ribose phosphate metabolic processGO:00196931450.025
protein maturationGO:0051604710.025
development of primary sexual characteristicsGO:0045137500.025
phagocytosisGO:00069092150.025
negative regulation of neuron differentiationGO:0045665160.025
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.025
spindle organizationGO:00070512530.024
epithelium migrationGO:00901321480.024
lipid localizationGO:0010876540.024
epithelial cell differentiationGO:00308553220.024
male courtship behaviorGO:0008049630.024
cell divisionGO:00513012480.024
cation homeostasisGO:0055080510.024
oxidation reduction processGO:00551141230.024
cytoskeleton dependent intracellular transportGO:0030705440.024
purine nucleoside catabolic processGO:00061521120.024
sensory perception of chemical stimulusGO:00076061160.024
response to organic cyclic compoundGO:0014070890.024
purine containing compound catabolic processGO:00725231120.024
organelle fissionGO:00482853400.023
Worm
polyol biosynthetic processGO:004617330.023
outflow tract morphogenesisGO:000315140.023
positive regulation of response to stimulusGO:00485843230.023
Human Mouse
cell deathGO:00082192790.023
response to oxygen containing compoundGO:19017002000.022
wing disc morphogenesisGO:00074723440.022
positive regulation of peptidase activityGO:0010952290.022
regulation of stress activated mapk cascadeGO:0032872410.022
positive regulation of biosynthetic processGO:00098913160.022
sensory perception of mechanical stimulusGO:0050954720.022
regulation of neuroblast proliferationGO:1902692340.021
purine ribonucleotide catabolic processGO:00091541090.021
centrosome cycleGO:00070981370.021
response to ecdysoneGO:0035075340.021
cellular response to endogenous stimulusGO:0071495800.021
response to sterolGO:0036314340.020
salivary gland morphogenesisGO:00074351450.020
microtubule polymerization or depolymerizationGO:0031109390.020
cilium morphogenesisGO:0060271390.020
response to ketoneGO:1901654340.020
protein modification by small protein conjugationGO:0032446790.019
response to other organismGO:00517072930.019
regulation of endocytosisGO:0030100370.019
larval developmentGO:00021641040.019
neuroblast developmentGO:0014019130.019
regulation of ras protein signal transductionGO:0046578930.019
segmentationGO:00352822070.019
cellular response to hormone stimulusGO:0032870440.019
protein catabolic processGO:00301631010.019
ribonucleoside metabolic processGO:00091191270.019
positive regulation of behaviorGO:0048520190.019
Human Mouse
multicellular organismal reproductive behaviorGO:00330571100.019
regulation of rho gtpase activityGO:0032319200.019
cellular response to nitrogen compoundGO:1901699510.018
eye photoreceptor cell developmentGO:0042462810.018
regulation of phosphorus metabolic processGO:00511742100.018
Human
positive regulation of phosphorus metabolic processGO:00105621390.018
Human
ribonucleotide catabolic processGO:00092611090.018
cellular response to peptide hormone stimulusGO:0071375280.018
aromatic compound catabolic processGO:00194391660.018
cellular protein complex assemblyGO:0043623710.018
organonitrogen compound catabolic processGO:19015651280.018
oocyte fate determinationGO:0030716270.018
compound eye photoreceptor cell differentiationGO:00017511400.018
regulation of catabolic processGO:00098941700.018
purine ribonucleoside triphosphate metabolic processGO:00092051190.017
positive regulation of cell communicationGO:00106472500.017
phagocytosis engulfmentGO:0006911110.017
central nervous system neuron axonogenesisGO:002195570.017
regulation of transportGO:00510491810.017
organonitrogen compound metabolic processGO:19015643180.017
cell maturationGO:00484691440.017
nucleoside phosphate metabolic processGO:00067531620.017
regulation of catalytic activityGO:00507901850.017
response to endogenous stimulusGO:00097191190.016
purine ribonucleotide metabolic processGO:00091501450.016
negative regulation of chemotaxisGO:005092210.016
photoreceptor cell differentiationGO:00465301700.016
rhythmic behaviorGO:0007622760.016
actin filament organizationGO:00070151260.016
positive regulation of translationGO:0045727120.016
regulation of cellular catabolic processGO:00313291570.016
nucleobase containing small molecule metabolic processGO:00550861740.016
regulation of cell deathGO:00109411730.016
organic substance catabolic processGO:19015753080.016
response to external biotic stimulusGO:00432072930.016
regulation of vesicle mediated transportGO:0060627590.016
anatomical structure homeostasisGO:0060249970.016
roundabout signaling pathwayGO:003538540.016
actin polymerization or depolymerizationGO:0008154310.016
response to inorganic substanceGO:0010035440.016
regulation of cell substrate adhesionGO:001081020.016
regulation of response to external stimulusGO:00321011150.016
Human Mouse
positive regulation of response to external stimulusGO:0032103440.015
Human Mouse
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.015
regulation of programmed cell deathGO:00430671520.015
regulation of extent of cell growthGO:006138780.015
Human Mouse
regulation of response to oxidative stressGO:190288240.015
detection of stimulusGO:00516061560.015
nucleotide metabolic processGO:00091171610.015
nucleoside triphosphate catabolic processGO:00091431080.014
skeletal muscle organ developmentGO:0060538480.014
muscle cell differentiationGO:00426921030.014
regulation of phosphate metabolic processGO:00192202100.014
Human
stem cell proliferationGO:0072089880.014
gonad developmentGO:0008406500.014
centrosome duplicationGO:00512981210.014
nucleoside phosphate catabolic processGO:19012921100.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.014
chemosensory behaviorGO:00076351060.014
positive regulation of ras protein signal transductionGO:0046579430.014
protein ubiquitinationGO:0016567700.014
regulation of protein localizationGO:0032880760.014
regulation of cellular protein metabolic processGO:00322682430.014
histone h3 k9 modificationGO:0061647120.014
neuronal stem cell divisionGO:0036445350.014
muscle organ developmentGO:00075171270.014
positive regulation of cellular component movementGO:0051272110.013
Human Mouse
positive regulation of protein metabolic processGO:00512471280.013
programmed cell deathGO:00125012570.013
cellular catabolic processGO:00442483720.013
epithelial cell migrationGO:00106311480.013
positive regulation of cellular catabolic processGO:0031331950.013
spermatogenesisGO:00072832000.013
stem cell differentiationGO:00488631170.013
protein modification by small protein conjugation or removalGO:00706471060.013
positive regulation of hydrolase activityGO:0051345780.013
cytoplasmic transportGO:00164821300.013
gene silencingGO:00164581380.012
regulation of cytoskeleton organizationGO:0051493890.012
organic cyclic compound catabolic processGO:19013611680.012
startle responseGO:0001964160.012
antennal morphogenesisGO:0048800140.012
cellular response to sterolGO:0036315170.012
pupariationGO:0035073140.012
formation of anatomical boundaryGO:0048859370.012
negative regulation of cell projection organizationGO:0031345130.012
convergent extension involved in gastrulationGO:006002720.012
glycosyl compound metabolic processGO:19016571270.012
regulation of locomotionGO:0040012420.012
Human Mouse
intracellular steroid hormone receptor signaling pathwayGO:0030518120.012
carbohydrate biosynthetic processGO:0016051170.011
compound eye developmentGO:00487493070.011
eye photoreceptor cell differentiationGO:00017541450.011
ribonucleoside triphosphate metabolic processGO:00091991190.011
sensory perceptionGO:00076001960.011
reproductive behaviorGO:00190981220.011
positive regulation of signalingGO:00230562430.011
single organismal cell cell adhesionGO:0016337450.011
membrane organizationGO:00610241120.011
establishment of organelle localizationGO:00516561220.011
mitotic dna damage checkpointGO:0044773740.011
cilium assemblyGO:0042384380.011
negative regulation of developmental growthGO:0048640640.011
response to woundingGO:0009611940.011
positive regulation of gtp catabolic processGO:0033126430.010
regulation of cell motilityGO:2000145230.010
organophosphate catabolic processGO:00464341120.010
regulation of lamellipodium assemblyGO:0010591150.010
cellular response to insulin stimulusGO:0032869280.010
macromolecule catabolic processGO:00090571610.010
negative regulation of neuron deathGO:1901215180.010
cellular component maintenanceGO:0043954230.010
blood circulationGO:0008015260.010
actin filament polymerizationGO:0030041270.010
multi organism reproductive behaviorGO:00447051210.010

Dscam disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.058
sensory system diseaseDOID:005015500.048
nervous system diseaseDOID:86300.048
eye diseaseDOID:561400.016
eye and adnexa diseaseDOID:149200.016