Drosophila melanogaster

65 known processes

unpg (Dmel_CG1650)

unplugged

(Aliases: unp,Dmel\CG1650,anon-45C,CG1650,upg,Gbx)

unpg biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of transcription dna templatedGO:00458932660.059
Fly
negative regulation of response to stimulusGO:00485852580.058
positive regulation of rna biosynthetic processGO:19026802660.056
Fly
sensory organ morphogenesisGO:00905962600.055
Mouse Fly
transcription from rna polymerase ii promoterGO:00063663680.054
Fly
neuron projection guidanceGO:00974852410.051
Mouse
regulation of transcription from rna polymerase ii promoterGO:00063573780.050
Fly
positive regulation of macromolecule metabolic processGO:00106044050.050
Fly
chemotaxisGO:00069352490.049
Mouse
tube developmentGO:00352952440.048
Zebrafish Mouse
positive regulation of nitrogen compound metabolic processGO:00511733540.046
Fly
cell deathGO:00082192790.045
body morphogenesisGO:001017120.043
positive regulation of rna metabolic processGO:00512542710.043
Fly
locomotory behaviorGO:00076261760.043
Mouse
positive regulation of biosynthetic processGO:00098913160.043
Fly
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.042
Fly
compound eye morphogenesisGO:00017452490.042
Fly
respiratory system developmentGO:00605412130.041
taxisGO:00423303040.041
Mouse
positive regulation of nucleic acid templated transcriptionGO:19035082660.041
Fly
eye developmentGO:00016543230.040
Fly
regulation of multicellular organismal developmentGO:20000264140.040
regionalizationGO:00030024160.040
Zebrafish Mouse
kidney developmentGO:000182230.038
cell proliferationGO:00082832990.038
Mouse
neuron fate commitmentGO:0048663500.038
Mouse Fly
negative regulation of nitrogen compound metabolic processGO:00511722650.037
Fly
cell migrationGO:00164772380.037
Mouse
establishment of localization in cellGO:00516494020.036
deathGO:00162652840.036
morphogenesis of an epitheliumGO:00020092760.035
Mouse Fly
protein localizationGO:00081042840.035
photoreceptor cell differentiationGO:00465301700.035
Fly
axon developmentGO:00615642970.035
Mouse Fly
negative regulation of nucleobase containing compound metabolic processGO:00459342610.034
Fly
negative regulation of transcription dna templatedGO:00458922370.034
Fly
single organism behaviorGO:00447083910.033
Mouse
segmentationGO:00352822070.033
negative regulation of cellular biosynthetic processGO:00313272770.033
Fly
axonogenesisGO:00074092900.032
Mouse Fly
axon guidanceGO:00074112330.031
Mouse
embryonic pattern specificationGO:00098801740.031
positive regulation of cellular biosynthetic processGO:00313283160.031
Fly
programmed cell deathGO:00125012570.031
negative regulation of cellular metabolic processGO:00313243820.031
Fly
regulation of anatomical structure morphogenesisGO:00226032420.030
Zebrafish
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.029
Fly
organonitrogen compound metabolic processGO:19015643180.029
notch signaling pathwayGO:00072191200.029
negative regulation of rna metabolic processGO:00512532510.028
Fly
compound eye developmentGO:00487493070.028
Fly
response to abiotic stimulusGO:00096283410.028
establishment or maintenance of cell polarityGO:00071631670.028
Fly
regulation of intracellular signal transductionGO:19025312360.028
negative regulation of biosynthetic processGO:00098902770.027
Fly
single organism cellular localizationGO:19025801800.027
dendrite morphogenesisGO:00488131990.027
regulation of cell cycleGO:00517262910.027
regulation of notch signaling pathwayGO:00085931000.026
digestive tract morphogenesisGO:00485461270.026
negative regulation of gene expressionGO:00106293870.026
Fly
localization of cellGO:00516742570.026
Mouse
digestive tract developmentGO:00485651490.025
regulation of localizationGO:00328792750.025
response to organic substanceGO:00100332840.025
cellular protein modification processGO:00064644380.025
cell motilityGO:00488702510.025
Mouse
positive regulation of gene expressionGO:00106282900.025
Fly
intracellular transportGO:00469072280.024
telencephalon developmentGO:002153720.024
regulation of cellular ketone metabolic processGO:001056530.024
defense responseGO:00069523000.024
compound eye photoreceptor cell differentiationGO:00017511400.024
Fly
protein modification processGO:00362114380.024
negative regulation of rna biosynthetic processGO:19026792400.023
Fly
blastoderm segmentationGO:00073501590.023
chromosome organizationGO:00512763600.023
cell fate specificationGO:0001708710.023
regulation of cell proliferationGO:00421271630.023
regulation of cell deathGO:00109411730.023
regulation of cell differentiationGO:00455953020.023
camera type eye developmentGO:004301040.023
lateral inhibitionGO:00463312060.023
Fly
negative regulation of nucleic acid templated transcriptionGO:19035072400.022
Fly
response to external biotic stimulusGO:00432072930.022
response to other organismGO:00517072930.022
negative regulation of signal transductionGO:00099682060.022
forebrain developmentGO:003090020.022
Mouse
open tracheal system developmentGO:00074242040.022
homeostatic processGO:00425921990.022
regulation of organelle organizationGO:00330431960.022
digestive system developmentGO:00551231490.022
positive regulation of nucleobase containing compound metabolic processGO:00459353320.021
Fly
immune system processGO:00023763470.021
dorsal ventral pattern formationGO:00099531330.021
connective tissue developmentGO:006144830.021
imaginal disc pattern formationGO:0007447910.020
organic substance transportGO:00717022570.020
phosphorylationGO:00163102940.020
appendage morphogenesisGO:00351073970.020
circulatory system developmentGO:0072359820.020
Mouse
organic acid metabolic processGO:00060821030.020
gland morphogenesisGO:00226121450.020
regulation of phosphorylationGO:00423251470.020
protein transportGO:00150311550.020
cellular macromolecule localizationGO:00707272200.020
positive regulation of macromolecule biosynthetic processGO:00105572830.020
Fly
establishment of protein localizationGO:00451841630.020
tube morphogenesisGO:00352391910.019
Mouse
negative regulation of macromolecule biosynthetic processGO:00105582700.019
Fly
central nervous system developmentGO:00074172010.019
exocrine system developmentGO:00352721620.019
immune responseGO:00069552460.019
mitotic nuclear divisionGO:00070672130.019
gliogenesisGO:0042063800.019
dna metabolic processGO:00062592270.019
cell maturationGO:00484691440.019
synaptic transmissionGO:00072682880.019
eye morphogenesisGO:00485922600.019
Fly
cellular component assembly involved in morphogenesisGO:00109271510.019
embryonic axis specificationGO:00005781070.018
developmental growthGO:00485892800.018
tissue morphogenesisGO:00487292970.018
Mouse Fly
imaginal disc derived appendage developmentGO:00487373990.018
regulation of cellular amine metabolic processGO:003323830.018
head developmentGO:00603221350.018
apoptotic processGO:00069151590.018
cellularizationGO:0007349900.017
regulation of immune system processGO:00026821760.017
regulation of synaptic transmissionGO:0050804690.017
positive regulation of cell communicationGO:00106472500.017
regulation of behaviorGO:0050795750.017
epithelial cell differentiationGO:00308553220.017
Fly
intracellular signal transductionGO:00355563000.017
regulation of mitotic cell cycleGO:00073461900.017
axis specificationGO:00097981670.017
neurological system processGO:00508773580.017
Mouse
nephron developmentGO:007200630.017
brain developmentGO:00074201200.017
cellular response to chemical stimulusGO:00708871990.017
developmental maturationGO:00217001720.017
organelle fissionGO:00482853400.016
regulation of cellular localizationGO:00603411360.016
carbohydrate derivative metabolic processGO:19011352170.016
regulation of response to external stimulusGO:00321011150.016
salivary gland morphogenesisGO:00074351450.016
imaginal disc derived wing morphogenesisGO:00074763370.016
compound eye photoreceptor fate commitmentGO:0001752360.016
Fly
compound eye photoreceptor developmentGO:0042051780.016
malpighian tubule morphogenesisGO:0007443440.016
rna processingGO:00063961470.016
positive regulation of signalingGO:00230562430.016
chromatin organizationGO:00063252070.016
renal tubule morphogenesisGO:0061333440.016
single organism intracellular transportGO:19025822070.016
anterior posterior axis specification embryoGO:00085951030.016
nuclear divisionGO:00002803320.016
regulation of apoptotic processGO:00429811300.016
organic substance catabolic processGO:19015753080.016
hindgut developmentGO:0061525580.015
negative regulation of cell communicationGO:00106482230.015
positive regulation of response to stimulusGO:00485843230.015
negative regulation of multicellular organismal processGO:00512411420.015
oxoacid metabolic processGO:00434361030.015
neuron recognitionGO:00080381010.015
catabolic processGO:00090564090.015
enzyme linked receptor protein signaling pathwayGO:00071671790.015
dendrite developmentGO:00163582040.015
carboxylic acid metabolic processGO:0019752920.015
appendage developmentGO:00487364010.015
defense response to bacteriumGO:00427421780.015
urogenital system developmentGO:0001655720.015
regulation of cell cycle processGO:00105641810.015
rhythmic behaviorGO:0007622760.015
tripartite regional subdivisionGO:00073511030.015
photoreceptor cell fate commitmentGO:0046552410.015
Fly
immune effector processGO:0002252980.014
growthGO:00400073590.014
oocyte axis specificationGO:00073091080.014
cell fate determinationGO:0001709910.014
regulation of developmental growthGO:00486381740.014
columnar cuboidal epithelial cell differentiationGO:00020652560.014
Fly
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.014
anterior posterior axis specificationGO:00099481090.014
mrna metabolic processGO:00160711240.014
eye photoreceptor cell differentiationGO:00017541450.014
Fly
phagocytosisGO:00069092150.014
positive regulation of developmental processGO:00510941430.014
regulation of programmed cell deathGO:00430671520.014
anterior posterior pattern specificationGO:00099521360.014
Zebrafish Mouse
wound healingGO:0042060750.014
hindbrain developmentGO:003090220.014
Zebrafish Mouse
gland developmentGO:00487321910.014
hindgut morphogenesisGO:0007442580.014
response to biotic stimulusGO:00096072940.014
spermatid developmentGO:0007286980.014
oocyte constructionGO:00073081120.014
actin cytoskeleton organizationGO:00300362060.014
ovarian follicle cell developmentGO:00307072480.014
salivary gland developmentGO:00074311620.014
post embryonic appendage morphogenesisGO:00351203850.014
intracellular mrna localization involved in pattern specification processGO:0060810560.013
regulation of cellular component biogenesisGO:00440872010.013
organelle assemblyGO:00709251980.013
eye photoreceptor cell developmentGO:0042462810.013
immune response activating signal transductionGO:000275720.013
eye antennal disc developmentGO:0035214600.013
cell cell signaling involved in cell fate commitmentGO:00451682100.013
Fly
eye photoreceptor cell fate commitmentGO:0042706370.013
Fly
response to woundingGO:0009611940.013
mapk cascadeGO:00001651070.013
regulation of growthGO:00400082330.013
negative regulation of cell deathGO:0060548810.013
epithelial cell developmentGO:00020642740.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.013
spindle organizationGO:00070512530.013
negative regulation of developmental processGO:00510932010.013
positive regulation of cell motilityGO:200014730.013
sensory perceptionGO:00076001960.013
Mouse
stem cell proliferationGO:0072089880.013
chromatin modificationGO:00165681470.013
reproductive behaviorGO:00190981220.013
negative regulation of signalingGO:00230572190.012
gene silencingGO:00164581380.012
spermatid differentiationGO:00485151140.012
regulation of phosphate metabolic processGO:00192202100.012
cytoplasm organizationGO:0007028640.012
mesenchymal cell differentiationGO:004876210.012
Mouse
embryonic hindgut morphogenesisGO:0048619480.012
response to oxygen containing compoundGO:19017002000.012
embryonic morphogenesisGO:00485982060.012
Zebrafish Mouse
cellular response to oxygen containing compoundGO:1901701790.012
negative regulation of cellular component organizationGO:00511291080.012
sensory perception of painGO:001923340.012
negative regulation of mitotic cell cycleGO:00459301090.012
photoreceptor cell developmentGO:0042461960.012
cellular amino acid metabolic processGO:0006520610.012
positive regulation of cell migrationGO:003033520.012
mitotic spindle organizationGO:00070522200.012
dorsal ventral axis specificationGO:0009950660.012
regulation of nervous system developmentGO:00519602480.012
regulation of rna splicingGO:0043484690.012
malpighian tubule developmentGO:0072002640.012
innate immune responseGO:00450871440.012
neuroblast proliferationGO:0007405740.012
spermatogenesisGO:00072832000.012
regulation of embryonic developmentGO:0045995680.012
Zebrafish
muscle structure developmentGO:00610612240.012
chaeta morphogenesisGO:0008407420.012
regulation of protein localizationGO:0032880760.012
regulation of phosphorus metabolic processGO:00511742100.011
histolysisGO:00075591020.011
positive regulation of signal transductionGO:00099672230.011
neural precursor cell proliferationGO:0061351750.011
Mouse
small molecule metabolic processGO:00442813050.011
ribonucleotide metabolic processGO:00092591450.011
monocarboxylic acid transportGO:001571830.011
regulation of response to stressGO:00801342000.011
cuticle developmentGO:0042335860.011
organic cyclic compound catabolic processGO:19013611680.011
cellular catabolic processGO:00442483720.011
amine metabolic processGO:0009308120.011
macromolecular complex assemblyGO:00650032560.011
mesenchymal cell developmentGO:001403110.011
Mouse
oocyte anterior posterior axis specificationGO:0007314720.011
regulation of cell morphogenesisGO:00226041630.011
mrna processingGO:00063971040.011
stem cell differentiationGO:00488631170.011
Mouse
oocyte differentiationGO:00099941450.011
cation transportGO:00068121100.011
synapse organizationGO:00508081960.011
retina development in camera type eyeGO:006004140.011
camera type eye morphogenesisGO:004859320.011
cellular amine metabolic processGO:0044106120.011
regulation of cellular amino acid metabolic processGO:000652100.011
regulation of cell developmentGO:00602842150.011
regulation of gene expression epigeneticGO:00400291280.011
regulation of synapse structure and activityGO:00508031280.011
cellular protein localizationGO:00346131600.011
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.011
Fly
cell divisionGO:00513012480.011
pole plasm rna localizationGO:0007316520.011
regulation of mapk cascadeGO:0043408920.011
peptide metabolic processGO:0006518800.011
embryonic organ developmentGO:0048568500.011
Mouse
cell recognitionGO:00080371020.011
cellular response to dna damage stimulusGO:00069742230.011
epithelial cell migrationGO:00106311480.011
segment specificationGO:0007379330.010
endomembrane system organizationGO:00102561190.010
nucleoside triphosphate metabolic processGO:00091411200.010
dna packagingGO:0006323910.010
leg disc developmentGO:0035218920.010
pole plasm oskar mrna localizationGO:0045451460.010
response to lipopolysaccharideGO:003249640.010
endodermal cell differentiationGO:003598730.010
regulation of neuron differentiationGO:00456641030.010
single organism membrane organizationGO:0044802930.010
renal tubule developmentGO:0061326640.010
regulation of mrna splicing via spliceosomeGO:0048024640.010
cell projection assemblyGO:0030031940.010
mrna splicing via spliceosomeGO:0000398730.010
activation of innate immune responseGO:000221840.010
intracellular mrna localizationGO:0008298660.010
maternal determination of anterior posterior axis embryoGO:0008358740.010
posttranscriptional regulation of gene expressionGO:00106081450.010
positive regulation of cellular amino acid metabolic processGO:004576400.010
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.010

unpg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.038
urinary system diseaseDOID:1800.014
kidney diseaseDOID:55700.014
acquired metabolic diseaseDOID:006015800.012
familial visceral amyloidosisDOID:005063600.012
amyloidosisDOID:912000.012
disease of metabolismDOID:001466700.012