IMP: Integrative Multi-species Prediction

Drosophila melanogaster

15 known processes

Dbp73D (Dmel_CG9680)

Dead box protein 73D

(Aliases: CG9680,DBP73D,DmRH7,Dmel\CG9680)

Entrez: 39871
FLYBASE: FBgn0004556
UniProtKB: P26802

Process Predictions
Disease Predictions

Dbp73D biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
rrna processing	GO:0006364	3	0.748	Yeast
rna processing	GO:0006396	147	0.281	Yeast
organelle assembly	GO:0070925	198	0.230
establishment of localization in cell	GO:0051649	402	0.185
macromolecular complex assembly	GO:0065003	256	0.180
multicellular organismal reproductive behavior	GO:0033057	110	0.124
mrna catabolic process	GO:0006402	33	0.115
digestive system development	GO:0055123	149	0.108
cellular catabolic process	GO:0044248	372	0.101
organic cyclic compound catabolic process	GO:1901361	168	0.086
regulation of cell cycle	GO:0051726	291	0.086
establishment or maintenance of cell polarity	GO:0007163	167	0.082
dendrite development	GO:0016358	204	0.081
organelle localization	GO:0051640	148	0.081
ribonucleoprotein complex biogenesis	GO:0022613	31	0.080	Yeast
nucleobase containing compound catabolic process	GO:0034655	165	0.076
cellular macromolecular complex assembly	GO:0034622	153	0.075
ribosome biogenesis	GO:0042254	8	0.072	Yeast
cell division	GO:0051301	248	0.070
regulation of mitotic cell cycle	GO:0007346	190	0.066
cellular macromolecule localization	GO:0070727	220	0.065
ribonucleoprotein complex subunit organization	GO:0071826	28	0.065
vesicle mediated transport	GO:0016192	381	0.064	Worm
heterocycle catabolic process	GO:0046700	166	0.063
larval development	GO:0002164	104	0.062	Worm
mitotic g2 m transition checkpoint	GO:0044818	70	0.060
positive regulation of macromolecule metabolic process	GO:0010604	405	0.059
ribosomal large subunit biogenesis	GO:0042273	1	0.059	Yeast
organic substance catabolic process	GO:1901575	308	0.056
regulation of protein metabolic process	GO:0051246	256	0.055
rna catabolic process	GO:0006401	37	0.055
positive regulation of rna metabolic process	GO:0051254	271	0.052
ncrna metabolic process	GO:0034660	43	0.051	Yeast
macromolecule catabolic process	GO:0009057	161	0.049
positive regulation of cellular biosynthetic process	GO:0031328	316	0.047
rna localization	GO:0006403	115	0.047
multi organism behavior	GO:0051705	175	0.045
cell death	GO:0008219	279	0.045
regulation of cell cycle process	GO:0010564	181	0.045
mitotic dna damage checkpoint	GO:0044773	74	0.040
regulation of cellular protein metabolic process	GO:0032268	243	0.039
nuclear transcribed mrna catabolic process	GO:0000956	24	0.038
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.037
regulation of cell development	GO:0060284	215	0.037
response to abiotic stimulus	GO:0009628	341	0.036
programmed cell death	GO:0012501	257	0.035
negative regulation of cell cycle	GO:0045786	116	0.035
aromatic compound catabolic process	GO:0019439	166	0.034
nuclear transport	GO:0051169	72	0.034
mrna processing	GO:0006397	104	0.034
ribonucleoprotein complex assembly	GO:0022618	23	0.033
cytokinetic process	GO:0032506	27	0.033
cellular nitrogen compound catabolic process	GO:0044270	165	0.032
regulation of multicellular organismal development	GO:2000026	414	0.032
regulation of cell differentiation	GO:0045595	302	0.032
regulation of developmental growth	GO:0048638	174	0.032
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.032
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.031
catabolic process	GO:0009056	409	0.030
muscle structure development	GO:0061061	224	0.029
endocytosis	GO:0006897	310	0.029	Worm
positive regulation of gene expression	GO:0010628	290	0.029
positive regulation of multicellular organismal process	GO:0051240	143	0.028
positive regulation of signal transduction	GO:0009967	223	0.028
protein modification process	GO:0036211	438	0.028
translation	GO:0006412	69	0.028
regulation of translation	GO:0006417	56	0.028
phosphorylation	GO:0016310	294	0.028
negative regulation of cellular metabolic process	GO:0031324	382	0.027
rna phosphodiester bond hydrolysis	GO:0090501	17	0.027
mrna metabolic process	GO:0016071	124	0.027
intracellular transport	GO:0046907	228	0.026
embryo development ending in birth or egg hatching	GO:0009792	152	0.026
mitotic g2 dna damage checkpoint	GO:0007095	69	0.026
dendrite morphogenesis	GO:0048813	199	0.025
positive regulation of signaling	GO:0023056	243	0.024
growth	GO:0040007	359	0.024
mitotic dna integrity checkpoint	GO:0044774	75	0.024
regulation of neuron differentiation	GO:0045664	103	0.024
cellular macromolecule catabolic process	GO:0044265	136	0.024
protein complex biogenesis	GO:0070271	201	0.024
nuclear import	GO:0051170	51	0.024
negative regulation of molecular function	GO:0044092	51	0.023
cellular protein complex assembly	GO:0043623	71	0.023
cytokinesis	GO:0000910	90	0.023
regulation of nervous system development	GO:0051960	248	0.022
establishment of cell polarity	GO:0030010	40	0.022
gland morphogenesis	GO:0022612	145	0.022
positive regulation of developmental process	GO:0051094	143	0.022
actin filament based process	GO:0030029	220	0.021
rna 3 end processing	GO:0031123	45	0.021
positive regulation of cell communication	GO:0010647	250	0.021
regulation of mrna processing	GO:0050684	71	0.021
regulation of organelle organization	GO:0033043	196	0.020
negative regulation of gene expression	GO:0010629	387	0.020
establishment of organelle localization	GO:0051656	122	0.020
negative regulation of cellular biosynthetic process	GO:0031327	277	0.020
nucleocytoplasmic transport	GO:0006913	72	0.020
developmental growth	GO:0048589	280	0.020
organic substance transport	GO:0071702	257	0.020
striated muscle myosin thick filament assembly	GO:0071688	3	0.020
ncrna processing	GO:0034470	30	0.020	Yeast
regulation of gene expression epigenetic	GO:0040029	128	0.020
regulation of glial cell proliferation	GO:0060251	11	0.019
defense response	GO:0006952	300	0.019
skeletal muscle fiber development	GO:0048741	3	0.019
cellular protein modification process	GO:0006464	438	0.019
regulation of phosphorus metabolic process	GO:0051174	210	0.018
regulation of neurogenesis	GO:0050767	158	0.018
regulation of cellular localization	GO:0060341	136	0.018
regulation of protein ubiquitination	GO:0031396	22	0.018
negative regulation of developmental process	GO:0051093	201	0.018
positive regulation of developmental growth	GO:0048639	62	0.018
response to organic substance	GO:0010033	284	0.018
protein import into nucleus	GO:0006606	51	0.017
transcription from rna polymerase ii promoter	GO:0006366	368	0.017
exocrine system development	GO:0035272	162	0.017
mitotic cell cycle phase transition	GO:0044772	138	0.016
regulation of mrna splicing via spliceosome	GO:0048024	64	0.016
regulation of establishment of protein localization	GO:0070201	61	0.016
positive regulation of rna biosynthetic process	GO:1902680	266	0.016
regulation of cell size	GO:0008361	63	0.016
negative regulation of cell death	GO:0060548	81	0.016
response to oxygen containing compound	GO:1901700	200	0.016
localization of cell	GO:0051674	257	0.015
negative regulation of cellular protein metabolic process	GO:0032269	85	0.015
chromosome organization	GO:0051276	360	0.015
regulation of nucleocytoplasmic transport	GO:0046822	35	0.015
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.015
oocyte construction	GO:0007308	112	0.015
nucleoside phosphate metabolic process	GO:0006753	162	0.015
protein dna complex subunit organization	GO:0071824	86	0.015
dna integrity checkpoint	GO:0031570	81	0.015
multi multicellular organism process	GO:0044706	123	0.015
chromatin organization	GO:0006325	207	0.015
negative regulation of biosynthetic process	GO:0009890	277	0.015
negative regulation of mitotic cell cycle	GO:0045930	109	0.015
positive regulation of multicellular organism growth	GO:0040018	21	0.015
sex differentiation	GO:0007548	81	0.014
protein localization	GO:0008104	284	0.014
regulation of molecular function	GO:0065009	217	0.014
gliogenesis	GO:0042063	80	0.014
posttranscriptional gene silencing	GO:0016441	46	0.014
organophosphate metabolic process	GO:0019637	195	0.014
regionalization	GO:0003002	416	0.014
protein targeting	GO:0006605	64	0.014
g2 dna damage checkpoint	GO:0031572	69	0.014
post embryonic appendage morphogenesis	GO:0035120	385	0.013
protein localization to organelle	GO:0033365	82	0.013
single organism cellular localization	GO:1902580	180	0.013
cellular protein localization	GO:0034613	160	0.013
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.013
establishment of protein localization	GO:0045184	163	0.013
axon development	GO:0061564	297	0.013
negative regulation of cell cycle phase transition	GO:1901988	103	0.013
single organism catabolic process	GO:0044712	228	0.013
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.013
death	GO:0016265	284	0.013
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.013
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.013
regulation of transport	GO:0051049	181	0.013
negative regulation of protein metabolic process	GO:0051248	85	0.013
glial cell proliferation	GO:0014009	13	0.013
salivary gland histolysis	GO:0035070	88	0.013
positive regulation of response to stimulus	GO:0048584	323	0.013
alternative mrna splicing via spliceosome	GO:0000380	60	0.013
notch signaling pathway	GO:0007219	120	0.012
protein targeting to nucleus	GO:0044744	51	0.012
nuclear transcribed mrna catabolic process deadenylation dependent decay	GO:0000288	14	0.012
negative regulation of cell cycle process	GO:0010948	109	0.012
protein complex assembly	GO:0006461	200	0.012
posttranscriptional regulation of gene expression	GO:0010608	145	0.012
response to hypoxia	GO:0001666	53	0.012
positive regulation of transcription dna templated	GO:0045893	266	0.012
cellular component assembly involved in morphogenesis	GO:0010927	151	0.012
body morphogenesis	GO:0010171	2	0.012
response to other organism	GO:0051707	293	0.012
regulation of cell cycle phase transition	GO:1901987	130	0.012
organonitrogen compound metabolic process	GO:1901564	318	0.012
response to endogenous stimulus	GO:0009719	119	0.011
organ growth	GO:0035265	56	0.011
dna damage checkpoint	GO:0000077	78	0.011
microtubule organizing center organization	GO:0031023	168	0.011
spindle organization	GO:0007051	253	0.011
salivary gland development	GO:0007431	162	0.011
negative regulation of programmed cell death	GO:0043069	72	0.011
cell proliferation	GO:0008283	299	0.011
protein import	GO:0017038	55	0.011
cell cycle phase transition	GO:0044770	140	0.011
appendage morphogenesis	GO:0035107	397	0.011
negative regulation of cell communication	GO:0010648	223	0.011
defense response to bacterium	GO:0042742	178	0.011
rna splicing via transesterification reactions	GO:0000375	73	0.011
oxidation reduction process	GO:0055114	123	0.011
cellular response to dna damage stimulus	GO:0006974	223	0.011
regulation of mrna metabolic process	GO:1903311	72	0.011
positive regulation of binding	GO:0051099	4	0.011
regulation of protein modification process	GO:0031399	112	0.011
single organism intracellular transport	GO:1902582	207	0.011
protein transport	GO:0015031	155	0.011
regulation of phosphate metabolic process	GO:0019220	210	0.010
response to biotic stimulus	GO:0009607	294	0.010
axonogenesis	GO:0007409	290	0.010
response to fungus	GO:0009620	50	0.010
protein phosphorylation	GO:0006468	169	0.010
gastrulation	GO:0007369	70	0.010

Dbp73D disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.016
	nervous system disease	DOID:863	0	0.010

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