Drosophila melanogaster

52 known processes

mthl1 (Dmel_CG4521)

methuselah-like 1

(Aliases: anon-WO0170980.23,anon-WO0170980.22,CG4521,Dmel\CG4521,Mth-1)

mthl1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
appendage morphogenesisGO:00351073970.139
imaginal disc derived appendage morphogenesisGO:00351143950.109
wing disc morphogenesisGO:00074723440.059
imaginal disc derived appendage developmentGO:00487373990.057
post embryonic appendage morphogenesisGO:00351203850.056
positive regulation of nitrogen compound metabolic processGO:00511733540.048
cell proliferationGO:00082832990.046
appendage developmentGO:00487364010.046
intracellular signal transductionGO:00355563000.044
negative regulation of nitrogen compound metabolic processGO:00511722650.044
positive regulation of response to stimulusGO:00485843230.042
negative regulation of gene expressionGO:00106293870.039
regulation of phosphate metabolic processGO:00192202100.039
leg disc developmentGO:0035218920.039
response to abiotic stimulusGO:00096283410.038
Fly
positive regulation of macromolecule metabolic processGO:00106044050.038
dna metabolic processGO:00062592270.038
negative regulation of rna biosynthetic processGO:19026792400.035
negative regulation of biosynthetic processGO:00098902770.035
chromosome organizationGO:00512763600.034
negative regulation of rna metabolic processGO:00512532510.034
organonitrogen compound metabolic processGO:19015643180.033
imaginal disc derived wing morphogenesisGO:00074763370.033
negative regulation of transcription dna templatedGO:00458922370.033
endocytosisGO:00068973100.033
programmed cell deathGO:00125012570.032
regulation of cellular ketone metabolic processGO:001056530.032
negative regulation of cellular metabolic processGO:00313243820.032
phosphorylationGO:00163102940.032
positive regulation of cell communicationGO:00106472500.032
taxisGO:00423303040.032
positive regulation of signal transductionGO:00099672230.031
regulation of cellular amine metabolic processGO:003323830.031
regulation of mitotic cell cycleGO:00073461900.031
organic substance catabolic processGO:19015753080.031
negative regulation of cellular biosynthetic processGO:00313272770.030
regulation of phosphorus metabolic processGO:00511742100.030
neurological system processGO:00508773580.030
negative regulation of nucleic acid templated transcriptionGO:19035072400.029
ras protein signal transductionGO:0007265880.029
negative regulation of macromolecule biosynthetic processGO:00105582700.029
organic substance transportGO:00717022570.029
positive regulation of signalingGO:00230562430.028
vesicle mediated transportGO:00161923810.028
Fly
catabolic processGO:00090564090.028
neuron projection guidanceGO:00974852410.028
imaginal disc derived leg morphogenesisGO:0007480800.027
respiratory system developmentGO:00605412130.027
deathGO:00162652840.027
carboxylic acid metabolic processGO:0019752920.027
cellular protein modification processGO:00064644380.027
regionalizationGO:00030024160.026
cell deathGO:00082192790.026
axonogenesisGO:00074092900.026
negative regulation of nucleobase containing compound metabolic processGO:00459342610.026
negative regulation of response to stimulusGO:00485852580.026
cell motilityGO:00488702510.026
regulation of cellular amino acid metabolic processGO:000652100.025
regulation of intracellular signal transductionGO:19025312360.025
eye developmentGO:00016543230.025
cellular catabolic processGO:00442483720.025
protein modification processGO:00362114380.025
central nervous system developmentGO:00074172010.025
positive regulation of cellular biosynthetic processGO:00313283160.025
ion transportGO:00068111450.025
actin filament based processGO:00300292200.025
epithelial cell developmentGO:00020642740.024
salivary gland developmentGO:00074311620.024
negative regulation of cell cycle processGO:00109481090.024
cell divisionGO:00513012480.024
small molecule metabolic processGO:00442813050.024
response to lipopolysaccharideGO:003249640.024
mapk cascadeGO:00001651070.024
compound eye developmentGO:00487493070.024
regulation of cellular catabolic processGO:00313291570.024
single organism catabolic processGO:00447122280.024
ovarian follicle cell developmentGO:00307072480.023
single organism behaviorGO:00447083910.023
chemotaxisGO:00069352490.023
transcription from rna polymerase ii promoterGO:00063663680.023
cell cycle checkpointGO:0000075950.023
regulation of cellular component biogenesisGO:00440872010.023
negative regulation of cell communicationGO:00106482230.022
regulation of phosphorylationGO:00423251470.022
axon guidanceGO:00074112330.022
gene silencingGO:00164581380.022
phagocytosisGO:00069092150.022
dna conformation changeGO:00711031050.022
positive regulation of nucleobase containing compound metabolic processGO:00459353320.022
leg disc morphogenesisGO:0007478800.021
single organism biosynthetic processGO:00447112060.021
mitotic nuclear divisionGO:00070672130.021
negative regulation of signal transductionGO:00099682060.021
positive regulation of gene expressionGO:00106282900.021
tube morphogenesisGO:00352391910.021
tissue morphogenesisGO:00487292970.021
organic cyclic compound catabolic processGO:19013611680.021
gland morphogenesisGO:00226121450.021
chromatin organizationGO:00063252070.021
sensory organ morphogenesisGO:00905962600.021
actin cytoskeleton organizationGO:00300362060.021
cellular macromolecule localizationGO:00707272200.021
macromolecular complex assemblyGO:00650032560.021
defense responseGO:00069523000.021
lateral inhibitionGO:00463312060.021
ribonucleoside catabolic processGO:00424541120.020
connective tissue developmentGO:006144830.020
positive regulation of nucleic acid templated transcriptionGO:19035082660.020
axon developmentGO:00615642970.020
response to other organismGO:00517072930.020
positive regulation of biosynthetic processGO:00098913160.020
negative regulation of mitotic cell cycle phase transitionGO:19019911030.020
organelle fissionGO:00482853400.020
regulation of cell proliferationGO:00421271630.020
small gtpase mediated signal transductionGO:0007264880.019
adult behaviorGO:00305341370.019
cellular ketone metabolic processGO:0042180240.019
regulation of molecular functionGO:00650092170.019
columnar cuboidal epithelial cell differentiationGO:00020652560.019
morphogenesis of an epitheliumGO:00020092760.019
protein localizationGO:00081042840.019
negative regulation of mitotic cell cycleGO:00459301090.019
negative regulation of gene expression epigeneticGO:0045814770.019
protein phosphorylationGO:00064681690.019
positive regulation of phosphorus metabolic processGO:00105621390.019
enzyme linked receptor protein signaling pathwayGO:00071671790.019
response to alcoholGO:0097305950.019
positive regulation of macromolecule biosynthetic processGO:00105572830.019
purine ribonucleoside catabolic processGO:00461301120.018
cellular nitrogen compound catabolic processGO:00442701650.018
androgen metabolic processGO:000820910.018
camera type eye developmentGO:004301040.018
signal transduction by phosphorylationGO:00230141070.018
rna processingGO:00063961470.018
spindle organizationGO:00070512530.018
purine ribonucleotide catabolic processGO:00091541090.018
positive regulation of cell migrationGO:003033520.018
forebrain developmentGO:003090020.018
chromatin modificationGO:00165681470.018
exocrine system developmentGO:00352721620.018
regulation of localizationGO:00328792750.018
cellular amine metabolic processGO:0044106120.018
columnar cuboidal epithelial cell developmentGO:00020662490.018
regulation of catabolic processGO:00098941700.018
regulation of multicellular organismal developmentGO:20000264140.018
anion homeostasisGO:005508130.018
amine metabolic processGO:0009308120.018
salivary gland morphogenesisGO:00074351450.018
regulation of cytoskeleton organizationGO:0051493890.018
cell migrationGO:00164772380.018
positive regulation of cell motilityGO:200014730.018
regulation of protein metabolic processGO:00512462560.017
tube developmentGO:00352952440.017
developmental growthGO:00485892800.017
purine nucleotide metabolic processGO:00061631460.017
negative regulation of cell cycleGO:00457861160.017
positive regulation of rna biosynthetic processGO:19026802660.017
apoptotic processGO:00069151590.017
response to radiationGO:00093141550.017
organic acid metabolic processGO:00060821030.017
regulation of cell cycle processGO:00105641810.017
positive regulation of phosphate metabolic processGO:00459371390.017
establishment of localization in cellGO:00516494020.017
Fly
developmental programmed cell deathGO:00106231380.017
protein complex assemblyGO:00064612000.017
establishment or maintenance of cell polarityGO:00071631670.017
homeostatic processGO:00425921990.017
mitotic cell cycle phase transitionGO:00447721380.017
regulation of programmed cell deathGO:00430671520.017
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.017
negative regulation of signalingGO:00230572190.017
positive regulation of cellular component organizationGO:00511301560.017
carbohydrate derivative metabolic processGO:19011352170.017
regulation of mapk cascadeGO:0043408920.017
compound eye morphogenesisGO:00017452490.016
regulation of cell developmentGO:00602842150.016
compound eye photoreceptor cell differentiationGO:00017511400.016
purine nucleoside metabolic processGO:00422781270.016
ribonucleoside triphosphate catabolic processGO:00092031080.016
regulation of ras protein signal transductionGO:0046578930.016
positive regulation of cellular amine metabolic processGO:003324000.016
dendrite morphogenesisGO:00488131990.016
body morphogenesisGO:001017120.016
negative regulation of cell cycle phase transitionGO:19019881030.016
immune system processGO:00023763470.016
ribonucleoside metabolic processGO:00091191270.016
regulation of response to stressGO:00801342000.016
regulation of cell cycleGO:00517262910.016
hormone catabolic processGO:004244730.016
oxoacid metabolic processGO:00434361030.016
gland developmentGO:00487321910.016
response to organic substanceGO:00100332840.016
Fly
regulation of cell cycle phase transitionGO:19019871300.016
purine ribonucleoside metabolic processGO:00461281270.016
regulation of gene expression epigeneticGO:00400291280.016
regulation of organelle organizationGO:00330431960.016
dna packagingGO:0006323910.016
proteolysisGO:00065081920.016
telencephalon developmentGO:002153720.015
nuclear divisionGO:00002803320.015
response to light stimulusGO:00094161240.015
regulation of mitotic cell cycle phase transitionGO:19019901300.015
notch signaling pathwayGO:00072191200.015
nucleoside phosphate metabolic processGO:00067531620.015
nucleobase containing small molecule metabolic processGO:00550861740.015
purine nucleoside triphosphate metabolic processGO:00091441190.015
protein complex biogenesisGO:00702712010.015
epithelial cell differentiationGO:00308553220.015
regulation of notch signaling pathwayGO:00085931000.015
cellular response to lipopolysaccharideGO:007122230.015
regulation of cellular protein metabolic processGO:00322682430.015
phosphate ion transportGO:000681740.015
heterocycle catabolic processGO:00467001660.015
response to temperature stimulusGO:00092661060.015
Fly
regulation of cell deathGO:00109411730.015
cellular protein localizationGO:00346131600.015
sister chromatid segregationGO:0000819920.015
photoreceptor cell differentiationGO:00465301700.015
peptidyl threonine phosphorylationGO:001810720.015
head developmentGO:00603221350.015
ribose phosphate metabolic processGO:00196931450.014
purine ribonucleotide metabolic processGO:00091501450.014
lipid metabolic processGO:00066291210.014
positive regulation of phosphorylationGO:0042327870.014
sodium dependent phosphate transportGO:004434120.014
sensory perceptionGO:00076001960.014
cellular response to chemical stimulusGO:00708871990.014
multi multicellular organism processGO:00447061230.014
carbohydrate derivative catabolic processGO:19011361180.014
regulation of transcription from rna polymerase ii promoterGO:00063573780.014
regulation of catalytic activityGO:00507901850.014
cellular response to molecule of bacterial originGO:007121930.014
cholesterol transportGO:003030120.014
immune response regulating signaling pathwayGO:000276420.014
peptidyl threonine modificationGO:001821030.014
mitotic sister chromatid segregationGO:0000070870.014
cellular response to radiationGO:0071478520.014
macromolecule catabolic processGO:00090571610.014
response to external biotic stimulusGO:00432072930.014
cell cell signaling involved in cell fate commitmentGO:00451682100.014
positive regulation of catabolic processGO:00098961050.014
eye morphogenesisGO:00485922600.014
ribonucleotide metabolic processGO:00092591450.014
purine ribonucleoside triphosphate metabolic processGO:00092051190.014
intracellular transportGO:00469072280.014
growthGO:00400073590.014
nucleobase containing compound catabolic processGO:00346551650.014
nucleoside metabolic processGO:00091161270.014
purine nucleoside triphosphate catabolic processGO:00091461080.014
response to oxygen containing compoundGO:19017002000.014
Fly
organonitrogen compound biosynthetic processGO:19015661170.014
establishment of organelle localizationGO:00516561220.014
Fly
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.014
organophosphate metabolic processGO:00196371950.014
positive regulation of catalytic activityGO:00430851180.014
chromosome segregationGO:00070591570.014
regulation of transportGO:00510491810.014
positive regulation of cellular catabolic processGO:0031331950.014
l amino acid importGO:004309220.014
purine nucleoside catabolic processGO:00061521120.014
cellular amino acid metabolic processGO:0006520610.014
protein transportGO:00150311550.014
nucleoside catabolic processGO:00091641120.014
dendrite developmentGO:00163582040.014
regulation of nervous system developmentGO:00519602480.014
ameboidal type cell migrationGO:00016671510.014
regulation of anatomical structure sizeGO:00900661630.014
endomembrane system organizationGO:00102561190.014
purine containing compound metabolic processGO:00725211550.014
tissue migrationGO:00901301550.014
jnk cascadeGO:0007254500.013
tissue deathGO:00162711020.013
regulation of apoptotic processGO:00429811300.013
detection of stimulusGO:00516061560.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
regulation of immune system processGO:00026821760.013
wnt signaling pathwayGO:0016055980.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.013
cell adhesionGO:00071551360.013
actin filament organizationGO:00070151260.013
nucleoside triphosphate catabolic processGO:00091431080.013
nucleotide metabolic processGO:00091171610.013
positive regulation of intracellular signal transductionGO:19025331160.013
positive regulation of cellular protein metabolic processGO:00322701180.013
salivary gland histolysisGO:0035070880.013
positive regulation of multicellular organismal processGO:00512401430.013
lipopolysaccharide mediated signaling pathwayGO:003166310.013
positive regulation of molecular functionGO:00440931360.013
cell fate determinationGO:0001709910.013
organonitrogen compound catabolic processGO:19015651280.013
single organism intracellular transportGO:19025822070.013
cellular response to dna damage stimulusGO:00069742230.013
regulation of cell substrate adhesionGO:001081020.013
nucleoside phosphate catabolic processGO:19012921100.013
aromatic compound catabolic processGO:00194391660.013
response to biotic stimulusGO:00096072940.013
autophagic cell deathGO:0048102830.013
extrinsic apoptotic signaling pathwayGO:009719110.013
positive regulation of developmental processGO:00510941430.013
g protein coupled receptor signaling pathwayGO:00071861360.013
Fly
response to bacteriumGO:00096171980.013
glycosyl compound catabolic processGO:19016581120.013
developmental maturationGO:00217001720.013
intracellular protein transportGO:00068861040.013
positive regulation of protein metabolic processGO:00512471280.013
ribonucleotide catabolic processGO:00092611090.013
limb developmentGO:006017310.013
regulation of tube architecture open tracheal systemGO:0035152680.013
posttranscriptional regulation of gene expressionGO:00106081450.013
nucleotide catabolic processGO:00091661090.012
immune response activating signal transductionGO:000275720.012
autophagyGO:00069141080.012
dorsal ventral pattern formationGO:00099531330.012
negative regulation of multicellular organismal processGO:00512411420.012
digestive tract developmentGO:00485651490.012
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.012
purine containing compound catabolic processGO:00725231120.012
biological adhesionGO:00226101380.012
modification dependent macromolecule catabolic processGO:0043632790.012
cell maturationGO:00484691440.012
digestive system developmentGO:00551231490.012
organelle localizationGO:00516401480.012
Fly
localization of cellGO:00516742570.012
organophosphate catabolic processGO:00464341120.012
regulation of small gtpase mediated signal transductionGO:0051056930.012
axis specificationGO:00097981670.012
segmentationGO:00352822070.012
modification dependent protein catabolic processGO:0019941780.012
establishment of tissue polarityGO:0007164870.012
protein modification by small protein conjugationGO:0032446790.012
cellular homeostasisGO:0019725800.012
gtp metabolic processGO:0046039720.012
protein catabolic processGO:00301631010.012
cellular response to abiotic stimulusGO:0071214580.012
establishment of protein localizationGO:00451841630.012
glycosyl compound metabolic processGO:19016571270.012
kidney developmentGO:000182230.012
regulation of protein catabolic processGO:0042176550.012
chromatin assembly or disassemblyGO:0006333520.012
mitotic spindle organizationGO:00070522200.012
stem cell proliferationGO:0072089880.012
chaeta developmentGO:0022416970.012
epidermal growth factor receptor signaling pathwayGO:0007173580.012
digestive tract morphogenesisGO:00485461270.012
cell recognitionGO:00080371020.012
regulation of cell differentiationGO:00455953020.012
purine nucleotide catabolic processGO:00061951090.012
locomotory behaviorGO:00076261760.012
positive regulation of rna metabolic processGO:00512542710.012
immune responseGO:00069552460.012
response to hexoseGO:000974630.012
multi organism behaviorGO:00517051750.012
regulation of alternative mrna splicing via spliceosomeGO:0000381600.011
stress activated mapk cascadeGO:0051403520.011
protein maturationGO:0051604710.011
cell cycle phase transitionGO:00447701400.011
matingGO:00076181200.011
cilium morphogenesisGO:0060271390.011
response to paraquatGO:190156240.011
Fly
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
regulation of growthGO:00400082330.011
cellular component assembly involved in morphogenesisGO:00109271510.011
muscle organ developmentGO:00075171270.011
detection of external stimulusGO:0009581660.011
defense response to bacteriumGO:00427421780.011
salivary gland cell autophagic cell deathGO:0035071830.011
response to monosaccharideGO:003428440.011
regulation of cell shapeGO:00083601130.011
cellular response to organic substanceGO:00713101320.011
synapse organizationGO:00508081960.011
positive regulation of hydrolase activityGO:0051345780.011
defense response to other organismGO:00985422250.011
cell projection assemblyGO:0030031940.011
response to organophosphorusGO:004668320.011
wing disc pattern formationGO:0035222660.011
ubiquitin dependent protein catabolic processGO:0006511780.011
positive regulation of transcription dna templatedGO:00458932660.011
regulation of vesicle mediated transportGO:0060627590.011
embryonic pattern specificationGO:00098801740.011
regulation of cellular component sizeGO:0032535980.011
eye photoreceptor cell differentiationGO:00017541450.011
cellular macromolecule catabolic processGO:00442651360.011
protein heterooligomerizationGO:005129140.011
stem cell divisionGO:0017145690.011
epidermis developmentGO:0008544650.011
cellular protein catabolic processGO:0044257830.011
negative regulation of cellular component organizationGO:00511291080.011
histolysisGO:00075591020.011
stem cell differentiationGO:00488631170.011
eggshell formationGO:00307031050.011
gastrulationGO:0007369700.011
regulation of epithelial cell differentiationGO:003085640.011
anion transportGO:0006820410.011
monocarboxylic acid transportGO:001571830.011
mrna processingGO:00063971040.011
regulation of proteolysisGO:0030162870.011
retina development in camera type eyeGO:006004140.011
detection of abiotic stimulusGO:0009582660.011
regulation of anatomical structure morphogenesisGO:00226032420.011
cellular response to biotic stimulusGO:007121640.011
nitrogen compound transportGO:0071705850.011
regulation of mrna processingGO:0050684710.010
rna localizationGO:00064031150.010
phagocytosis recognitionGO:000691010.010
steroid catabolic processGO:000670610.010
embryonic morphogenesisGO:00485982060.010
vitamin metabolic processGO:000676620.010
nucleoside triphosphate metabolic processGO:00091411200.010
proteolysis involved in cellular protein catabolic processGO:0051603830.010
developmental growth involved in morphogenesisGO:0060560650.010
chromatin silencingGO:0006342760.010
phosphatidic acid metabolic processGO:004647310.010
protein ubiquitinationGO:0016567700.010
regulation of cellular response to stressGO:0080135890.010
neuroblast proliferationGO:0007405740.010
negative regulation of developmental processGO:00510932010.010
chromatin assemblyGO:0031497480.010
imaginal disc derived wing margin morphogenesisGO:0008587410.010

mthl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.039
nervous system diseaseDOID:86300.019
sensory system diseaseDOID:005015500.015
musculoskeletal system diseaseDOID:1700.012
eye and adnexa diseaseDOID:149200.012
eye diseaseDOID:561400.012