IMP: Integrative Multi-species Prediction

Drosophila melanogaster

75 known processes

CG8436 (Dmel_CG8436)

CG8436 gene product from transcript CG8436-RA

(Aliases: Dmel\CG8436)

FLYBASE: FBgn0037670
Entrez: 41103
UniProtKB: Q9VHG5

Process Predictions
Disease Predictions

CG8436 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
peptidyl amino acid modification	GO:0018193	105	0.157
intracellular transport	GO:0046907	228	0.153
histone modification	GO:0016570	106	0.129
covalent chromatin modification	GO:0016569	106	0.109
positive regulation of biosynthetic process	GO:0009891	316	0.092
peptidyl lysine modification	GO:0018205	57	0.085
chromosome organization	GO:0051276	360	0.080
cellular protein modification process	GO:0006464	438	0.076
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.072
positive regulation of response to stimulus	GO:0048584	323	0.067
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.067
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.067
regionalization	GO:0003002	416	0.065
protein acetylation	GO:0006473	39	0.063
transcription from rna polymerase ii promoter	GO:0006366	368	0.062
regulation of mrna processing	GO:0050684	71	0.060
positive regulation of signaling	GO:0023056	243	0.047
positive regulation of cell communication	GO:0010647	250	0.044
rna splicing	GO:0008380	83	0.043
nucleobase containing compound catabolic process	GO:0034655	165	0.043
small molecule metabolic process	GO:0044281	305	0.042
response to biotic stimulus	GO:0009607	294	0.042
organonitrogen compound metabolic process	GO:1901564	318	0.040
negative regulation of cellular metabolic process	GO:0031324	382	0.040
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.038
regulation of phosphate metabolic process	GO:0019220	210	0.037
endomembrane system organization	GO:0010256	119	0.036
mrna cis splicing via spliceosome	GO:0045292	1	0.036
negative regulation of developmental process	GO:0051093	201	0.035
chromatin modification	GO:0016568	147	0.035
histone acetylation	GO:0016573	38	0.035
positive regulation of macromolecule metabolic process	GO:0010604	405	0.035
positive regulation of gene expression	GO:0010628	290	0.034
chromatin organization	GO:0006325	207	0.034
regulation of gene expression epigenetic	GO:0040029	128	0.033
negative regulation of rna metabolic process	GO:0051253	251	0.032
chromosome segregation	GO:0007059	157	0.031
chromatin silencing	GO:0006342	76	0.029
phosphorylation	GO:0016310	294	0.029
muscle structure development	GO:0061061	224	0.029
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.029
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.029
negative regulation of chromosome organization	GO:2001251	19	0.029
gene silencing	GO:0016458	138	0.029
regulation of protein modification process	GO:0031399	112	0.028
rna processing	GO:0006396	147	0.028
negative regulation of transcription dna templated	GO:0045892	237	0.028
peptidyl lysine acetylation	GO:0018394	39	0.028
positive regulation of signal transduction	GO:0009967	223	0.027
regulation of mrna splicing via spliceosome	GO:0048024	64	0.026
regulation of cell differentiation	GO:0045595	302	0.026
phagocytosis	GO:0006909	215	0.025
positive regulation of transcription dna templated	GO:0045893	266	0.025
dna metabolic process	GO:0006259	227	0.025
cell division	GO:0051301	248	0.024
organic substance transport	GO:0071702	257	0.024
methylation	GO:0032259	47	0.024
response to heat	GO:0009408	63	0.023
aromatic compound catabolic process	GO:0019439	166	0.022
aging	GO:0007568	143	0.022
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.022
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.022
positive regulation of cellular biosynthetic process	GO:0031328	316	0.021
negative regulation of rna biosynthetic process	GO:1902679	240	0.021
rna splicing via transesterification reactions	GO:0000375	73	0.021
regulation of protein metabolic process	GO:0051246	256	0.021
organelle fission	GO:0048285	340	0.021
internal peptidyl lysine acetylation	GO:0018393	38	0.021
positive regulation of phosphorylation	GO:0042327	87	0.021
cell death	GO:0008219	279	0.021
negative regulation of programmed cell death	GO:0043069	72	0.020
regulation of phosphorylation	GO:0042325	147	0.020
histone methylation	GO:0016571	40	0.020
establishment of localization in cell	GO:0051649	402	0.020
signal transduction by phosphorylation	GO:0023014	107	0.020
histone h2a acetylation	GO:0043968	1	0.020
carboxylic acid metabolic process	GO:0019752	92	0.019
regulation of catalytic activity	GO:0050790	185	0.019
regulation of multicellular organismal development	GO:2000026	414	0.019
macromolecular complex assembly	GO:0065003	256	0.018
regulation of apoptotic process	GO:0042981	130	0.018
muscle organ development	GO:0007517	127	0.018
oocyte dorsal ventral axis specification	GO:0007310	34	0.018
negative regulation of cell differentiation	GO:0045596	143	0.018
positive regulation of phosphate metabolic process	GO:0045937	139	0.018
endocytosis	GO:0006897	310	0.018
internal protein amino acid acetylation	GO:0006475	38	0.018
positive regulation of rna biosynthetic process	GO:1902680	266	0.017
single organism behavior	GO:0044708	391	0.017
mrna processing	GO:0006397	104	0.017
response to other organism	GO:0051707	293	0.017
organic cyclic compound catabolic process	GO:1901361	168	0.017
regulation of gene silencing	GO:0060968	63	0.016
regulation of phosphorus metabolic process	GO:0051174	210	0.016
programmed cell death	GO:0012501	257	0.016
negative regulation of gene expression	GO:0010629	387	0.016
alternative mrna splicing via spliceosome	GO:0000380	60	0.015
protein acylation	GO:0043543	42	0.015
nucleoside phosphate metabolic process	GO:0006753	162	0.015
ribonucleotide metabolic process	GO:0009259	145	0.014
posttranscriptional gene silencing by rna	GO:0035194	45	0.014
negative regulation of chromatin silencing	GO:0031936	9	0.014
cellular nitrogen compound catabolic process	GO:0044270	165	0.014
death	GO:0016265	284	0.014
heterocycle catabolic process	GO:0046700	166	0.014
rna catabolic process	GO:0006401	37	0.014
regulation of cell death	GO:0010941	173	0.013
amine metabolic process	GO:0009308	12	0.013
protein dna complex subunit organization	GO:0071824	86	0.013
vesicle mediated transport	GO:0016192	381	0.013
multicellular organismal aging	GO:0010259	140	0.013
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.013
response to external biotic stimulus	GO:0043207	293	0.013
spermatogenesis	GO:0007283	200	0.012
mitotic nuclear division	GO:0007067	213	0.012
negative regulation of apoptotic process	GO:0043066	63	0.012
regulation of molecular function	GO:0065009	217	0.012
negative regulation of cellular biosynthetic process	GO:0031327	277	0.012
defense response to bacterium	GO:0042742	178	0.012
immune effector process	GO:0002252	98	0.012
positive regulation of mapk cascade	GO:0043410	63	0.012
protein localization	GO:0008104	284	0.012
apoptotic process	GO:0006915	159	0.012
regulation of cell division	GO:0051302	72	0.012
compound eye development	GO:0048749	307	0.012
regulation of mapk cascade	GO:0043408	92	0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.012
negative regulation of cell death	GO:0060548	81	0.012
positive regulation of rho protein signal transduction	GO:0035025	4	0.012
nitrogen compound transport	GO:0071705	85	0.011
positive regulation of phosphorus metabolic process	GO:0010562	139	0.011
mrna metabolic process	GO:0016071	124	0.011
regulation of programmed cell death	GO:0043067	152	0.011
intracellular signal transduction	GO:0035556	300	0.011
small gtpase mediated signal transduction	GO:0007264	88	0.011
sensory organ morphogenesis	GO:0090596	260	0.011
regulation of rna splicing	GO:0043484	69	0.011
ribonucleoprotein complex disassembly	GO:0032988	1	0.011
regulation of ras protein signal transduction	GO:0046578	93	0.010
establishment of rna localization	GO:0051236	47	0.010
protein modification process	GO:0036211	438	0.010
regulation of dna metabolic process	GO:0051052	34	0.010
oxoacid metabolic process	GO:0043436	103	0.010
gland development	GO:0048732	191	0.010

CG8436 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	chromosomal disease	DOID:0080014	0	0.016
	disease of anatomical entity	DOID:7	0	0.012

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