Drosophila melanogaster

50 known processes

MED1 (Dmel_CG7162)

Mediator complex subunit 1

(Aliases: Trap220,Dmel\CG7162,dTRAP220,Med1/SOP3/TRAP220,Med1,CG7162)

MED1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromosome organizationGO:00512763600.557
chromatin modificationGO:00165681470.201
organelle assemblyGO:00709251980.181
chromatin organizationGO:00063252070.168
positive regulation of gene expressionGO:00106282900.119
localization of cellGO:00516742570.108
positive regulation of biosynthetic processGO:00098913160.099
establishment of localization in cellGO:00516494020.098
histone modificationGO:00165701060.089
neuron projection guidanceGO:00974852410.089
cellular component disassemblyGO:0022411460.082
covalent chromatin modificationGO:00165691060.072
regulation of multicellular organismal developmentGO:20000264140.067
macromolecular complex assemblyGO:00650032560.065
kidney developmentGO:000182230.063
regulation of cell developmentGO:00602842150.061
muscle organ developmentGO:00075171270.061
cell motilityGO:00488702510.060
single organism intracellular transportGO:19025822070.060
mitotic g2 m transition checkpointGO:0044818700.057
positive regulation of cellular biosynthetic processGO:00313283160.055
rna splicingGO:0008380830.055
aromatic compound catabolic processGO:00194391660.054
positive regulation of rna metabolic processGO:00512542710.050
chromatin remodelingGO:0006338720.048
protein modification by small protein conjugation or removalGO:00706471060.048
establishment or maintenance of cell polarityGO:00071631670.047
positive regulation of rna biosynthetic processGO:19026802660.047
deathGO:00162652840.046
taxisGO:00423303040.045
positive regulation of apoptotic signaling pathwayGO:200123540.044
immune system processGO:00023763470.044
proteolysis involved in cellular protein catabolic processGO:0051603830.043
negative regulation of mitotic cell cycle phase transitionGO:19019911030.043
body morphogenesisGO:001017120.042
cellular protein modification processGO:00064644380.042
negative regulation of gene expressionGO:00106293870.042
axon guidanceGO:00074112330.041
protein modification processGO:00362114380.039
cell migrationGO:00164772380.039
central nervous system developmentGO:00074172010.039
establishment or maintenance of cytoskeleton polarityGO:0030952440.038
negative regulation of cellular metabolic processGO:00313243820.037
cell divisionGO:00513012480.036
histone acetylationGO:0016573380.036
head developmentGO:00603221350.035
positive regulation of nitrogen compound metabolic processGO:00511733540.035
negative regulation of programmed cell deathGO:0043069720.035
axon regenerationGO:003110380.034
chemotaxisGO:00069352490.034
growthGO:00400073590.034
tube morphogenesisGO:00352391910.033
axon developmentGO:00615642970.033
carboxylic acid metabolic processGO:0019752920.032
positive regulation of signalingGO:00230562430.032
positive regulation of response to stimulusGO:00485843230.032
apoptotic processGO:00069151590.032
embryo development ending in birth or egg hatchingGO:00097921520.031
cellular catabolic processGO:00442483720.031
negative regulation of cell cycle phase transitionGO:19019881030.031
regulation of catalytic activityGO:00507901850.030
cellular response to dna damage stimulusGO:00069742230.030
response to organic substanceGO:00100332840.030
larval developmentGO:00021641040.030
cellular macromolecule catabolic processGO:00442651360.029
protein modification by small protein conjugationGO:0032446790.029
imaginal disc growthGO:0007446370.029
proteolysisGO:00065081920.029
internal peptidyl lysine acetylationGO:0018393380.028
negative regulation of cell cycle processGO:00109481090.028
signal transduction by phosphorylationGO:00230141070.028
regulation of cellular amino acid metabolic processGO:000652100.028
cellular amino acid metabolic processGO:0006520610.028
regulation of localizationGO:00328792750.027
organic substance catabolic processGO:19015753080.027
regulation of cellular localizationGO:00603411360.027
positive regulation of cell communicationGO:00106472500.027
regulation of mitotic cell cycleGO:00073461900.027
phosphorylationGO:00163102940.027
regulation of cell cycleGO:00517262910.026
catabolic processGO:00090564090.026
negative regulation of apoptotic processGO:0043066630.026
negative regulation of cell deathGO:0060548810.026
positive regulation of signal transductionGO:00099672230.026
intracellular transportGO:00469072280.025
regulation of neurogenesisGO:00507671580.025
protein complex assemblyGO:00064612000.025
nuclear rna surveillanceGO:007102730.025
cellular macromolecular complex assemblyGO:00346221530.025
cell proliferationGO:00082832990.025
positive regulation of intracellular signal transductionGO:19025331160.025
hindbrain developmentGO:003090220.024
negative regulation of cell cycleGO:00457861160.024
positive regulation of phosphate metabolic processGO:00459371390.024
positive regulation of macromolecule metabolic processGO:00106044050.024
gene silencingGO:00164581380.024
regulation of mapk cascadeGO:0043408920.024
positive regulation of developmental processGO:00510941430.023
cytoplasmic transportGO:00164821300.023
response to sterolGO:0036314340.023
regulation of molecular functionGO:00650092170.023
embryonic morphogenesisGO:00485982060.023
hematopoietic or lymphoid organ developmentGO:0048534570.023
vesicle mediated transportGO:00161923810.023
brain developmentGO:00074201200.023
modification dependent macromolecule catabolic processGO:0043632790.023
macromolecule catabolic processGO:00090571610.023
regulation of embryonic developmentGO:0045995680.023
regulation of cell projection organizationGO:0031344920.022
regulation of cellular amine metabolic processGO:003323830.022
organelle localizationGO:00516401480.022
protein phosphorylationGO:00064681690.022
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.022
developmental growthGO:00485892800.022
axonogenesisGO:00074092900.022
positive regulation of phosphorus metabolic processGO:00105621390.021
intracellular signal transductionGO:00355563000.021
dna metabolic processGO:00062592270.021
homeostatic processGO:00425921990.021
cell deathGO:00082192790.021
cellular ketone metabolic processGO:0042180240.021
endocytosisGO:00068973100.021
reproductive system developmentGO:0061458740.021
organic cyclic compound catabolic processGO:19013611680.021
chromosome segregationGO:00070591570.020
microtubule organizing center organizationGO:00310231680.020
negative regulation of cell developmentGO:0010721620.020
centrosome organizationGO:00512971630.020
positive regulation of macromolecule biosynthetic processGO:00105572830.019
regulation of phosphate metabolic processGO:00192202100.019
single organism cellular localizationGO:19025801800.019
mitotic dna integrity checkpointGO:0044774750.019
establishment of protein localizationGO:00451841630.019
negative regulation of biosynthetic processGO:00098902770.019
peptidyl lysine modificationGO:0018205570.019
regulation of phosphorus metabolic processGO:00511742100.019
muscle structure developmentGO:00610612240.018
regulation of transportGO:00510491810.018
cellular protein catabolic processGO:0044257830.018
organic acid metabolic processGO:00060821030.018
digestive tract morphogenesisGO:00485461270.018
protein complex biogenesisGO:00702712010.018
cellular protein localizationGO:00346131600.017
organelle fissionGO:00482853400.017
cell cycle phase transitionGO:00447701400.017
epidermal growth factor receptor signaling pathwayGO:0007173580.017
macromolecular complex disassemblyGO:0032984370.017
digestive system developmentGO:00551231490.017
mitotic dna damage checkpointGO:0044773740.016
regulation of cellular ketone metabolic processGO:001056530.016
protein acetylationGO:0006473390.016
nucleocytoplasmic transportGO:0006913720.016
gastrulationGO:0007369700.016
mitotic sister chromatid segregationGO:0000070870.016
negative regulation of protein metabolic processGO:0051248850.016
regulation of cell cycle phase transitionGO:19019871300.016
hemopoiesisGO:0030097460.015
positive regulation of nucleobase containing compound metabolic processGO:00459353320.015
negative regulation of mitotic cell cycleGO:00459301090.015
cellular nitrogen compound catabolic processGO:00442701650.015
male gamete generationGO:00482322010.015
nuclear transportGO:0051169720.015
cellular component assembly involved in morphogenesisGO:00109271510.015
rhythmic processGO:00485111060.015
tube developmentGO:00352952440.015
response to ketoneGO:1901654340.015
cellular response to ketoneGO:1901655170.015
peptidyl amino acid modificationGO:00181931050.015
regulation of cell cycle processGO:00105641810.015
rna splicing via transesterification reactionsGO:0000375730.015
dna repairGO:0006281540.015
regulation of cellular protein metabolic processGO:00322682430.015
response to abiotic stimulusGO:00096283410.015
cell fate specificationGO:0001708710.015
nucleosome organizationGO:0034728590.014
dendrite developmentGO:00163582040.014
mrna processingGO:00063971040.014
positive regulation of nucleic acid templated transcriptionGO:19035082660.014
protein transportGO:00150311550.014
mitotic cell cycle phase transitionGO:00447721380.014
regulation of microtubule depolymerizationGO:0031114240.014
protein ubiquitinationGO:0016567700.014
negative regulation of rna biosynthetic processGO:19026792400.014
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.014
protein processingGO:0016485680.014
spindle organizationGO:00070512530.014
regulation of neuron differentiationGO:00456641030.014
transcription from rna polymerase ii promoterGO:00063663680.013
programmed cell deathGO:00125012570.013
protein depolymerizationGO:0051261310.013
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.013
indole containing compound biosynthetic processGO:004243540.013
immune system developmentGO:0002520570.013
protein catabolic processGO:00301631010.013
regulation of gene expression epigeneticGO:00400291280.013
protein targeting to nucleusGO:0044744510.013
cellular response to organic substanceGO:00713101320.013
regulation of vesicle mediated transportGO:0060627590.013
appendage developmentGO:00487364010.013
regulation of anatomical structure morphogenesisGO:00226032420.013
nuclear importGO:0051170510.013
neuroblast proliferationGO:0007405740.013
organonitrogen compound metabolic processGO:19015643180.013
positive regulation of cellular amine metabolic processGO:003324000.013
histone exchangeGO:0043486210.013
negative regulation of cellular biosynthetic processGO:00313272770.012
chromatin silencingGO:0006342760.012
larval lymph gland hemopoiesisGO:0035167170.012
negative regulation of nucleobase containing compound metabolic processGO:00459342610.012
cellular macromolecule localizationGO:00707272200.012
negative regulation of erk1 and erk2 cascadeGO:007037330.012
carbohydrate derivative metabolic processGO:19011352170.012
response to woundingGO:0009611940.012
regulation of nervous system developmentGO:00519602480.012
purine ribonucleoside triphosphate catabolic processGO:00092071080.012
cytokinesisGO:0000910900.012
imaginal disc derived appendage developmentGO:00487373990.012
response to ecdysoneGO:0035075340.012
internal protein amino acid acetylationGO:0006475380.012
mitotic cell cycle checkpointGO:0007093880.012
peptidyl lysine acetylationGO:0018394390.012
cellular response to chemical stimulusGO:00708871990.012
camera type eye developmentGO:004301040.012
mapk cascadeGO:00001651070.011
negative regulation of epithelial cell proliferationGO:005068040.011
reproductive structure developmentGO:0048608740.011
regulation of phosphorylationGO:00423251470.011
endomembrane system organizationGO:00102561190.011
cellular homeostasisGO:0019725800.011
regulation of hydrolase activityGO:0051336970.011
tissue morphogenesisGO:00487292970.011
sensory perception of soundGO:0007605560.011
mitotic cytokinesisGO:0000281500.011
enzyme linked receptor protein signaling pathwayGO:00071671790.011
regulation of apoptotic processGO:00429811300.011
neurological system processGO:00508773580.011
sex differentiationGO:0007548810.011
peptidyl tyrosine modificationGO:0018212240.011
mrna splicing via spliceosomeGO:0000398730.011
circulatory system developmentGO:0072359820.010
organic substance transportGO:00717022570.010
translationGO:0006412690.010
positive regulation of cell migrationGO:003033520.010
response to endogenous stimulusGO:00097191190.010
extrinsic apoptotic signaling pathwayGO:009719110.010
negative regulation of rna metabolic processGO:00512532510.010
protein import into nucleusGO:0006606510.010
negative regulation of response to stimulusGO:00485852580.010
embryonic hemopoiesisGO:0035162260.010

MED1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.047
disease of cellular proliferationDOID:1456600.026
cancerDOID:16200.017
organ system cancerDOID:005068600.014
musculoskeletal system diseaseDOID:1700.013
muscular diseaseDOID:008000000.013
muscle tissue diseaseDOID:6600.012
nervous system diseaseDOID:86300.010