Drosophila melanogaster

77 known processes

nec (Dmel_CG1857)

necrotic

(Aliases: Spn43Ac,Dmel\CG1857,Ser3,Nec,anon-WO0118057.3,CG1857,SER3)

nec biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pigment metabolic processGO:0042440840.620
axis specificationGO:00097981670.597
developmental pigmentationGO:0048066680.519
phenol containing compound metabolic processGO:0018958570.483
regulation of immune effector processGO:0002697520.427
Fly
taxisGO:00423303040.404
response to woundingGO:0009611940.399
Rat
response to bacteriumGO:00096171980.381
Fly
adult chitin containing cuticle pigmentationGO:0048085160.370
organonitrogen compound metabolic processGO:19015643180.357
Fly
response to fungusGO:0009620500.348
immune effector processGO:0002252980.344
Fly
regulation of response to biotic stimulusGO:0002831630.340
Fly
cuticle pigmentationGO:0048067220.335
negative regulation of cellular metabolic processGO:00313243820.322
response to biotic stimulusGO:00096072940.320
negative regulation of gene expressionGO:00106293870.312
regulation of multi organism processGO:00439001310.306
Fly
organic hydroxy compound metabolic processGO:1901615830.296
positive regulation of gene expressionGO:00106282900.286
positive regulation of nitrogen compound metabolic processGO:00511733540.286
pigmentationGO:0043473750.281
regulation of adult chitin containing cuticle pigmentationGO:0048082130.279
immune responseGO:00069552460.269
regulation of developmental pigmentationGO:0048070240.262
protein maturationGO:0051604710.249
Mouse Fly
regulation of response to external stimulusGO:00321011150.243
Rat Fly
regulation of chitin based cuticle tanningGO:0007564140.213
regulation of cuticle pigmentationGO:0048079160.205
dorsal ventral axis specificationGO:0009950660.189
appendage morphogenesisGO:00351073970.189
regulation of humoral immune responseGO:0002920510.188
Fly
innate immune responseGO:00450871440.186
peptide metabolic processGO:0006518800.182
Fly
regulation of catalytic activityGO:00507901850.177
defense response to bacteriumGO:00427421780.174
Fly
defense responseGO:00069523000.170
tissue morphogenesisGO:00487292970.161
secondary metabolic processGO:0019748750.159
chitin based cuticle sclerotizationGO:0007593190.157
response to abiotic stimulusGO:00096283410.156
positive regulation of defense responseGO:0031349590.145
circulatory system developmentGO:0072359820.140
immune system processGO:00023763470.139
defense response to other organismGO:00985422250.137
regulation of cellular amide metabolic processGO:0034248390.134
Fly
melanin metabolic processGO:0006582470.130
organonitrogen compound biosynthetic processGO:19015661170.128
humoral immune responseGO:00069591170.126
regulation of immune system processGO:00026821760.124
Fly
response to extracellular stimulusGO:00099911160.119
Rat
epithelium migrationGO:00901321480.116
regulation of response to stressGO:00801342000.114
Rat
hormone metabolic processGO:0042445330.110
Fly
wound healingGO:0042060750.109
Rat
endocytosisGO:00068973100.106
multi organism behaviorGO:00517051750.105
protein processingGO:0016485680.103
Fly
response to other organismGO:00517072930.102
negative regulation of nucleic acid templated transcriptionGO:19035072400.099
cellular amide metabolic processGO:0043603800.097
Fly
cellular catabolic processGO:00442483720.096
positive regulation of biosynthetic processGO:00098913160.095
negative regulation of biosynthetic processGO:00098902770.094
positive regulation of response to external stimulusGO:0032103440.094
negative regulation of signal transductionGO:00099682060.093
toll signaling pathwayGO:0008063250.091
positive regulation of cellular biosynthetic processGO:00313283160.090
pattern recognition receptor signaling pathwayGO:000222120.089
compound eye developmentGO:00487493070.088
response to external biotic stimulusGO:00432072930.088
melanization defense responseGO:0035006450.086
regulation of immune responseGO:00507761180.086
Fly
phagocytosisGO:00069092150.085
establishment of tissue polarityGO:0007164870.083
negative regulation of nucleobase containing compound metabolic processGO:00459342610.083
positive regulation of response to stimulusGO:00485843230.082
positive regulation of immune system processGO:0002684680.081
zymogen activationGO:0031638200.079
eye developmentGO:00016543230.077
molting cycle processGO:0022404290.076
defense response to fungusGO:0050832480.071
establishment of planar polarityGO:0001736870.069
positive regulation of nucleobase containing compound metabolic processGO:00459353320.065
regulation of anatomical structure morphogenesisGO:00226032420.064
pigment biosynthetic processGO:0046148360.064
immune response activating signal transductionGO:000275720.063
gene silencingGO:00164581380.062
positive regulation of antimicrobial humoral responseGO:0002760280.061
catabolic processGO:00090564090.060
peptide biosynthetic processGO:0043043420.060
organic acid metabolic processGO:00060821030.059
cell deathGO:00082192790.059
cell migrationGO:00164772380.058
cellular response to chemical stimulusGO:00708871990.058
Zebrafish
regulation of molecular functionGO:00650092170.056
positive regulation of antibacterial peptide productionGO:0002803200.055
regulation of i kappab kinase nf kappab signalingGO:004312220.055
regulation of cell differentiationGO:00455953020.053
developmental growthGO:00485892800.051
Rat
regulation of response to woundingGO:1903034190.050
Rat
regionalizationGO:00030024160.050
dorsal ventral pattern formationGO:00099531330.050
intracellular transportGO:00469072280.050
response to organic substanceGO:00100332840.049
Zebrafish
vesicle mediated transportGO:00161923810.048
epithelial tube morphogenesisGO:0060562880.048
sensory organ morphogenesisGO:00905962600.048
stress activated mapk cascadeGO:0051403520.047
exocrine system developmentGO:00352721620.046
response to nitrogen compoundGO:1901698900.046
cell cell junction organizationGO:0045216550.045
defense response to gram negative bacteriumGO:0050829940.045
Fly
imaginal disc derived appendage developmentGO:00487373990.044
negative regulation of macromolecule biosynthetic processGO:00105582700.043
positive regulation of immune responseGO:0050778630.043
production of molecular mediator of immune responseGO:0002440460.043
Fly
salivary gland developmentGO:00074311620.043
positive regulation of cell communicationGO:00106472500.042
ameboidal type cell migrationGO:00016671510.042
chemotaxisGO:00069352490.041
antimicrobial humoral responseGO:0019730990.041
antibacterial humoral responseGO:0019731440.040
biological adhesionGO:00226101380.039
Rat
synaptic transmissionGO:00072682880.039
small molecule metabolic processGO:00442813050.039
regulation of peptidase activityGO:0052547390.038
growthGO:00400073590.038
Rat
proteolysisGO:00065081920.037
defense response to virusGO:0051607230.037
regulation of defense responseGO:00313471020.037
Rat
negative regulation of rna metabolic processGO:00512532510.037
carbohydrate derivative metabolic processGO:19011352170.037
positive regulation of signalingGO:00230562430.037
developmental maturationGO:00217001720.036
regulation of multicellular organismal developmentGO:20000264140.036
regulation of antimicrobial humoral responseGO:0002759500.035
Fly
positive regulation of macromolecule metabolic processGO:00106044050.035
neuromuscular junction developmentGO:00075281490.035
wing disc morphogenesisGO:00074723440.034
post embryonic appendage morphogenesisGO:00351203850.034
negative regulation of gene expression epigeneticGO:0045814770.034
compound eye morphogenesisGO:00017452490.034
cardiovascular system developmentGO:0072358820.034
localization of cellGO:00516742570.034
positive regulation of humoral immune responseGO:0002922280.034
positive regulation of cell migrationGO:003033520.034
response to temperature stimulusGO:00092661060.033
regulation of antimicrobial peptide productionGO:0002784440.033
Fly
substrate adhesion dependent cell spreadingGO:003444620.033
organic substance catabolic processGO:19015753080.033
single organism carbohydrate metabolic processGO:0044723720.032
reproductive behaviorGO:00190981220.032
small molecule biosynthetic processGO:0044283370.032
negative regulation of cell communicationGO:00106482230.031
negative regulation of nitrogen compound metabolic processGO:00511722650.031
Fly
positive regulation of multi organism processGO:0043902400.031
positive regulation of rna metabolic processGO:00512542710.031
cell cell signaling involved in cell fate commitmentGO:00451682100.031
regulation of hydrolase activityGO:0051336970.030
tube developmentGO:00352952440.030
single organism cell adhesionGO:0098602470.030
cellular response to biotic stimulusGO:007121640.030
response to organic cyclic compoundGO:0014070890.030
Zebrafish
cuticle developmentGO:0042335860.030
positive regulation of response to biotic stimulusGO:0002833310.030
embryo development ending in birth or egg hatchingGO:00097921520.030
cellular protein localizationGO:00346131600.029
dendrite developmentGO:00163582040.029
deathGO:00162652840.029
protein modification processGO:00362114380.029
sex differentiationGO:0007548810.029
chromatin silencing at centromereGO:003070230.029
response to organophosphorusGO:004668320.028
regulation of transcription from rna polymerase ii promoterGO:00063573780.028
morphogenesis of an epitheliumGO:00020092760.028
purine containing compound metabolic processGO:00725211550.027
positive regulation of antimicrobial peptide productionGO:0002225280.027
regulation of cellular protein metabolic processGO:00322682430.027
positive regulation of nucleic acid templated transcriptionGO:19035082660.027
positive regulation of antimicrobial peptide biosynthetic processGO:0002807260.027
imaginal disc derived appendage morphogenesisGO:00351143950.027
regulation of production of molecular mediator of immune responseGO:0002700440.027
Fly
positive regulation of rna biosynthetic processGO:19026802660.026
negative regulation of response to stimulusGO:00485852580.026
single organism biosynthetic processGO:00447112060.026
Mouse
regulation of neuron deathGO:1901214260.026
tube morphogenesisGO:00352391910.026
cell motilityGO:00488702510.026
appendage developmentGO:00487364010.026
regulation of innate immune responseGO:0045088710.025
regulation of antimicrobial peptide biosynthetic processGO:0002805380.025
negative regulation of protein metabolic processGO:0051248850.024
open tracheal system developmentGO:00074242040.024
anion homeostasisGO:005508130.024
molting cycle chitin based cuticleGO:0007591560.024
positive regulation of catalytic activityGO:00430851180.024
oxoacid metabolic processGO:00434361030.024
activation of innate immune responseGO:000221840.023
tissue deathGO:00162711020.023
positive regulation of transcription dna templatedGO:00458932660.022
signal transduction by phosphorylationGO:00230141070.022
response to oxygen containing compoundGO:19017002000.022
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.022
positive regulation of molecular functionGO:00440931360.022
transcription from rna polymerase ii promoterGO:00063663680.022
dendrite morphogenesisGO:00488131990.021
regulation of protein metabolic processGO:00512462560.021
antimicrobial peptide biosynthetic processGO:0002777380.021
positive regulation of cell motilityGO:200014730.021
agingGO:00075681430.021
antibacterial peptide productionGO:0002778220.021
catechol containing compound biosynthetic processGO:000971330.021
positive regulation of macromolecule biosynthetic processGO:00105572830.021
mitotic cell cycle embryonicGO:0045448380.020
cellular response to organic substanceGO:00713101320.020
Zebrafish
regulation of cellular response to stressGO:0080135890.020
negative regulation of peptidase activityGO:0010466110.020
cellular response to molecule of bacterial originGO:007121930.020
cell divisionGO:00513012480.020
cell proliferationGO:00082832990.020
programmed cell deathGO:00125012570.020
macromolecular complex assemblyGO:00650032560.020
purine nucleoside metabolic processGO:00422781270.019
neurological system processGO:00508773580.019
hemolymph coagulationGO:0042381100.019
chromatin silencingGO:0006342760.019
synapse organizationGO:00508081960.019
muscle cell developmentGO:0055001500.019
gland developmentGO:00487321910.019
amide biosynthetic processGO:0043604420.019
regulation of cell adhesionGO:0030155270.019
Rat
lipid metabolic processGO:00066291210.018
salivary gland morphogenesisGO:00074351450.018
cellular amino acid metabolic processGO:0006520610.018
muscle organ developmentGO:00075171270.018
heart developmentGO:0007507820.018
regulation of toll signaling pathwayGO:0008592170.018
germ cell migrationGO:0008354430.018
response to lipopolysaccharideGO:003249640.018
respiratory system developmentGO:00605412130.018
intracellular protein transportGO:00068861040.018
wnt signaling pathwayGO:0016055980.018
positive regulation of i kappab kinase nf kappab signalingGO:004312310.018
forebrain developmentGO:003090020.017
regulation of cellular component biogenesisGO:00440872010.017
stress activated protein kinase signaling cascadeGO:0031098550.017
rhythmic processGO:00485111060.017
cell adhesionGO:00071551360.017
Rat
response to radiationGO:00093141550.017
carbohydrate metabolic processGO:0005975820.017
negative regulation of rna biosynthetic processGO:19026792400.017
nucleoside catabolic processGO:00091641120.017
homeostatic processGO:00425921990.016
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.016
regulation of phosphorus metabolic processGO:00511742100.016
multicellular organismal reproductive behaviorGO:00330571100.016
tyrosine metabolic processGO:000657010.016
regulation of cell proliferationGO:00421271630.016
negative regulation of cellular biosynthetic processGO:00313272770.015
lipid biosynthetic processGO:0008610460.015
regulation of secondary metabolic processGO:004345570.015
columnar cuboidal epithelial cell developmentGO:00020662490.015
positive regulation of production of molecular mediator of immune responseGO:0002702280.015
regulation of cell morphogenesis involved in differentiationGO:0010769610.015
larval developmentGO:00021641040.015
mapk cascadeGO:00001651070.015
gene silencing by rnaGO:0031047570.015
cellular component assembly involved in morphogenesisGO:00109271510.015
negative regulation of cellular protein metabolic processGO:0032269850.015
regulation of wnt signaling pathwayGO:0030111680.014
mesoderm developmentGO:0007498780.014
response to inorganic substanceGO:0010035440.014
actin filament based processGO:00300292200.014
determination of adult lifespanGO:00083401370.014
monocarboxylic acid transportGO:001571830.014
apoptotic processGO:00069151590.014
regulation of locomotionGO:0040012420.014
regulation of phosphate metabolic processGO:00192202100.014
dopamine biosynthetic processGO:004241630.014
neuron deathGO:0070997270.014
response to oxidative stressGO:0006979860.014
organic substance transportGO:00717022570.014
eye morphogenesisGO:00485922600.014
neuron projection guidanceGO:00974852410.014
cellular macromolecule localizationGO:00707272200.014
aromatic amino acid family metabolic processGO:000907230.014
positive regulation of multicellular organismal processGO:00512401430.014
intracellular signal transductionGO:00355563000.014
defense response to gram positive bacteriumGO:0050830410.014
segmentationGO:00352822070.013
carboxylic acid metabolic processGO:0019752920.013
regulation of establishment of planar polarityGO:0090175220.013
positive regulation of immune effector processGO:0002699280.013
cellular amine metabolic processGO:0044106120.013
negative regulation of molecular functionGO:0044092510.013
regulation of hormone levelsGO:0010817400.013
Fly
catecholamine biosynthetic processGO:004242330.013
mesenchymal cell developmentGO:001403110.013
hormone biosynthetic processGO:0042446200.013
single organism catabolic processGO:00447122280.013
chemical homeostasisGO:0048878920.013
negative regulation of catalytic activityGO:0043086420.013
molting cycleGO:0042303560.013
regulation of hemocyte differentiationGO:0045610220.013
establishment of protein localizationGO:00451841630.013
protein localizationGO:00081042840.012
response to virusGO:0009615280.012
blastoderm segmentationGO:00073501590.012
zygotic determination of anterior posterior axis embryoGO:0007354270.012
morphogenesis of a branching epitheliumGO:0061138450.012
regulation of antibacterial peptide biosynthetic processGO:0002808220.012
extrinsic apoptotic signaling pathwayGO:009719110.012
antibacterial peptide biosynthetic processGO:0002780220.012
positive regulation of innate immune responseGO:0045089380.012
negative regulation of transcription dna templatedGO:00458922370.012
axonogenesisGO:00074092900.012
aromatic compound catabolic processGO:00194391660.012
jnk cascadeGO:0007254500.012
regulation of localizationGO:00328792750.012
nucleoside metabolic processGO:00091161270.012
autophagic cell deathGO:0048102830.012
positive regulation of cellular amide metabolic processGO:0034250260.012
embryonic pattern specificationGO:00098801740.012
axon guidanceGO:00074112330.012
negative regulation of proteolysisGO:0045861310.011
r3 r4 cell fate commitmentGO:0007464100.011
amine metabolic processGO:0009308120.011
cellular response to external stimulusGO:0071496660.011
positive regulation of nervous system developmentGO:0051962690.011
carboxylic acid biosynthetic processGO:0046394150.011
regulation of cellular catabolic processGO:00313291570.011
response to reactive oxygen speciesGO:0000302240.011
protein transportGO:00150311550.011
macromolecule catabolic processGO:00090571610.011
epithelial cell migrationGO:00106311480.011
nucleoside phosphate metabolic processGO:00067531620.011
developmental growth involved in morphogenesisGO:0060560650.011
reproductive structure developmentGO:0048608740.011
cellular protein modification processGO:00064644380.011
response to dsrnaGO:0043331150.011
nucleobase containing small molecule metabolic processGO:00550861740.011
regulation of cell cycleGO:00517262910.011
negative regulation of multicellular organismal processGO:00512411420.011
extracellular matrix organizationGO:0030198320.011
Mouse
morphogenesis of a polarized epitheliumGO:0001738930.011
muscle structure developmentGO:00610612240.011
regulation of cell morphogenesisGO:00226041630.011
establishment of ommatidial planar polarityGO:0042067490.011
positive regulation of phosphorus metabolic processGO:00105621390.011
digestive system developmentGO:00551231490.011
innate immune response activating signal transductionGO:000275820.011
positive regulation of cell differentiationGO:0045597640.011
phosphorylationGO:00163102940.010
epithelial cell differentiationGO:00308553220.010
morphogenesis of a branching structureGO:0001763450.010
cellular response to endogenous stimulusGO:0071495800.010
Zebrafish
cellular response to lipidGO:0071396200.010
Zebrafish
positive regulation of cell deathGO:0010942690.010
positive regulation of phosphorylationGO:0042327870.010
kidney developmentGO:000182230.010
regulation of tube sizeGO:0035150460.010
tripartite regional subdivisionGO:00073511030.010
positive regulation of cellular component organizationGO:00511301560.010
response to endogenous stimulusGO:00097191190.010
Zebrafish

nec disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.018
disease of cellular proliferationDOID:1456600.018
cancerDOID:16200.018