Drosophila melanogaster

97 known processes

rb (Dmel_CG11427)

ruby

(Aliases: Dmel\CG11427,AP-3beta,beta3,Rb,cg11427,CG11427)

rb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ocellus pigment metabolic processGO:0046158190.921
eye pigment granule organizationGO:0008057120.832
ommochrome biosynthetic processGO:0006727190.817
cellular pigmentationGO:0033059120.805
vesicle organizationGO:0016050440.777
ommochrome metabolic processGO:0046152190.601
negative regulation of gene expressionGO:00106293870.563
endosomal transportGO:0016197440.521
pigment granule organizationGO:0048753120.520
pigmentationGO:0043473750.491
compound eye pigmentationGO:0048072170.467
ocellus pigment biosynthetic processGO:0008055190.451
developmental pigmentationGO:0048066680.398
cellular catabolic processGO:00442483720.390
eye pigment metabolic processGO:0042441330.372
multicellular organismal agingGO:00102591400.325
pigment biosynthetic processGO:0046148360.317
autophagyGO:00069141080.298
ocellus pigmentationGO:0033060190.267
macroautophagyGO:0016236420.205
negative regulation of macromolecule biosynthetic processGO:00105582700.172
small molecule metabolic processGO:00442813050.171
protein modification processGO:00362114380.171
agingGO:00075681430.162
determination of adult lifespanGO:00083401370.155
organic substance transportGO:00717022570.154
cellular protein modification processGO:00064644380.154
protein transportGO:00150311550.151
regulation of autophagyGO:0010506620.146
embryonic pattern specificationGO:00098801740.141
pigment metabolic processGO:0042440840.139
carboxylic acid metabolic processGO:0019752920.127
regulation of catabolic processGO:00098941700.124
synaptic transmissionGO:00072682880.123
Mouse
endocytosisGO:00068973100.123
positive regulation of nitrogen compound metabolic processGO:00511733540.116
positive regulation of proteolysisGO:0045862520.113
secondary metabolite biosynthetic processGO:0044550240.110
catabolic processGO:00090564090.109
negative regulation of signal transductionGO:00099682060.104
negative regulation of response to stimulusGO:00485852580.099
autophagic vacuole fusionGO:0000046150.095
cellular response to starvationGO:0009267610.095
establishment of protein localizationGO:00451841630.091
negative regulation of rna metabolic processGO:00512532510.091
organic acid metabolic processGO:00060821030.090
organic substance catabolic processGO:19015753080.088
gene silencingGO:00164581380.088
regulation of cell deathGO:00109411730.088
establishment of localization in cellGO:00516494020.088
negative regulation of cellular metabolic processGO:00313243820.082
pigment metabolic process involved in developmental pigmentationGO:0043324330.080
positive regulation of response to stimulusGO:00485843230.077
intracellular signal transductionGO:00355563000.077
single organism catabolic processGO:00447122280.074
cytoplasmic transportGO:00164821300.074
single organism intracellular transportGO:19025822070.071
Mouse
aromatic amino acid family metabolic processGO:000907230.069
columnar cuboidal epithelial cell differentiationGO:00020652560.069
cellular macromolecule catabolic processGO:00442651360.069
negative regulation of nitrogen compound metabolic processGO:00511722650.067
negative regulation of cell communicationGO:00106482230.067
tissue morphogenesisGO:00487292970.066
regionalizationGO:00030024160.062
protein localizationGO:00081042840.060
negative regulation of cellular biosynthetic processGO:00313272770.059
dorsal appendage formationGO:0046843470.058
posttranscriptional regulation of gene expressionGO:00106081450.058
heterocycle catabolic processGO:00467001660.057
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.057
cellular amino acid metabolic processGO:0006520610.055
pigment metabolic process involved in pigmentationGO:0043474330.054
regulation of proteolysisGO:0030162870.054
organelle membrane fusionGO:0090174160.053
response to abiotic stimulusGO:00096283410.051
intracellular transportGO:00469072280.051
Mouse
secretionGO:00469031090.051
endomembrane system organizationGO:00102561190.050
oxoacid metabolic processGO:00434361030.049
positive regulation of catabolic processGO:00098961050.048
regulation of notch signaling pathwayGO:00085931000.048
secondary metabolic processGO:0019748750.048
regulation of localizationGO:00328792750.048
regulation of multicellular organismal developmentGO:20000264140.047
locomotory behaviorGO:00076261760.047
enzyme linked receptor protein signaling pathwayGO:00071671790.047
blastoderm segmentationGO:00073501590.045
single organism membrane organizationGO:0044802930.045
columnar cuboidal epithelial cell developmentGO:00020662490.044
purine nucleoside triphosphate catabolic processGO:00091461080.044
positive regulation of gene expressionGO:00106282900.043
body morphogenesisGO:001017120.042
cellular macromolecule localizationGO:00707272200.042
glycosyl compound catabolic processGO:19016581120.041
amine metabolic processGO:0009308120.041
cellular response to extracellular stimulusGO:0031668640.040
regulation of neuron deathGO:1901214260.040
intracellular protein transportGO:00068861040.040
cuticle developmentGO:0042335860.040
protein modification by small protein conjugation or removalGO:00706471060.040
establishment of organelle localizationGO:00516561220.040
Mouse
organonitrogen compound metabolic processGO:19015643180.039
chitin based cuticle developmentGO:0040003490.037
regulation of cellular component biogenesisGO:00440872010.037
chemical homeostasisGO:0048878920.036
ion transportGO:00068111450.036
negative regulation of signalingGO:00230572190.036
vesicle mediated transportGO:00161923810.036
anterograde axon cargo transportGO:000808960.036
Mouse
ribonucleoside catabolic processGO:00424541120.035
cellular nitrogen compound catabolic processGO:00442701650.035
positive regulation of cellular catabolic processGO:0031331950.035
tube developmentGO:00352952440.035
single organism cellular localizationGO:19025801800.035
endosome to lysosome transportGO:000833370.033
cellular response to nutrient levelsGO:0031669620.032
neuron deathGO:0070997270.032
aromatic compound catabolic processGO:00194391660.032
epithelial cell differentiationGO:00308553220.032
segmentationGO:00352822070.031
regulation of hydrolase activityGO:0051336970.031
organelle assemblyGO:00709251980.031
positive regulation of cell deathGO:0010942690.031
anterograde synaptic vesicle transportGO:004849030.031
Mouse
positive regulation of cysteine type endopeptidase activityGO:2001056240.031
single organism behaviorGO:00447083910.031
carbohydrate derivative metabolic processGO:19011352170.031
carbohydrate derivative catabolic processGO:19011361180.030
positive regulation of multicellular organismal processGO:00512401430.030
macromolecule catabolic processGO:00090571610.030
protein complex assemblyGO:00064612000.030
regulation of intracellular signal transductionGO:19025312360.029
cellular protein catabolic processGO:0044257830.029
positive regulation of peptidase activityGO:0010952290.028
establishment of vesicle localizationGO:0051650510.028
Mouse
developmental maturationGO:00217001720.028
eye pigment biosynthetic processGO:0006726320.028
regulation of cellular protein metabolic processGO:00322682430.028
macromolecular complex assemblyGO:00650032560.028
negative regulation of nucleic acid templated transcriptionGO:19035072400.028
cellular response to organic substanceGO:00713101320.027
axis specificationGO:00097981670.027
embryonic morphogenesisGO:00485982060.027
regulation of cell cycleGO:00517262910.027
mitotic cell cycle phase transitionGO:00447721380.027
regulation of cellular component sizeGO:0032535980.026
ribose phosphate metabolic processGO:00196931450.026
regulation of mitotic cell cycleGO:00073461900.026
nucleotide catabolic processGO:00091661090.026
protein modification by small protein conjugationGO:0032446790.026
positive regulation of nucleobase containing compound metabolic processGO:00459353320.025
gene silencing by rnaGO:0031047570.025
organic cyclic compound catabolic processGO:19013611680.025
regulation of immune system processGO:00026821760.025
notch receptor processingGO:0007220130.025
response to starvationGO:0042594970.024
regulation of translationGO:0006417560.024
adult locomotory behaviorGO:0008344760.024
lipid storageGO:0019915380.023
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.023
regulation of erbb signaling pathwayGO:1901184420.023
morphogenesis of an epitheliumGO:00020092760.023
negative regulation of developmental processGO:00510932010.023
purine ribonucleotide catabolic processGO:00091541090.023
regulation of cellular catabolic processGO:00313291570.022
positive regulation of cell communicationGO:00106472500.022
notch signaling pathwayGO:00072191200.022
proteasomal protein catabolic processGO:0010498590.022
positive regulation of signal transductionGO:00099672230.022
cellular response to chemical stimulusGO:00708871990.021
ovarian follicle cell developmentGO:00307072480.021
cellular response to external stimulusGO:0071496660.021
negative regulation of notch signaling pathwayGO:0045746410.021
gtp catabolic processGO:0006184720.021
small gtpase mediated signal transductionGO:0007264880.021
regulation of apoptotic processGO:00429811300.021
cellular macromolecular complex assemblyGO:00346221530.021
nucleoside metabolic processGO:00091161270.021
regulation of cell cycle processGO:00105641810.021
organophosphate metabolic processGO:00196371950.020
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.020
negative regulation of nucleobase containing compound metabolic processGO:00459342610.020
regulation of anatomical structure morphogenesisGO:00226032420.020
growthGO:00400073590.020
cellular chemical homeostasisGO:0055082400.020
lysosomal transportGO:0007041130.020
regulation of cell morphogenesisGO:00226041630.020
regulation of cell differentiationGO:00455953020.020
chromosome organizationGO:00512763600.020
organonitrogen compound catabolic processGO:19015651280.020
cellular protein complex assemblyGO:0043623710.019
regulation of gene silencingGO:0060968630.019
regulation of response to stressGO:00801342000.019
epithelial cell developmentGO:00020642740.019
head involutionGO:0008258350.019
regulation of protein transportGO:0051223570.019
nucleoside triphosphate catabolic processGO:00091431080.019
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.019
peptidyl threonine phosphorylationGO:001810720.019
purine containing compound metabolic processGO:00725211550.018
regulation of establishment of protein localizationGO:0070201610.018
actin filament based processGO:00300292200.018
membrane fusionGO:0061025420.018
post embryonic appendage morphogenesisGO:00351203850.018
rna localizationGO:00064031150.017
embryo development ending in birth or egg hatchingGO:00097921520.017
purine nucleotide catabolic processGO:00061951090.017
protein targetingGO:0006605640.017
single organism biosynthetic processGO:00447112060.017
nucleoside catabolic processGO:00091641120.017
transcription from rna polymerase ii promoterGO:00063663680.017
purine ribonucleoside catabolic processGO:00461301120.017
cellular protein localizationGO:00346131600.017
nucleoside triphosphate metabolic processGO:00091411200.017
positive regulation of hydrolase activityGO:0051345780.017
ribonucleotide catabolic processGO:00092611090.017
chromatin modificationGO:00165681470.017
cell divisionGO:00513012480.017
positive regulation of endopeptidase activityGO:0010950260.017
modification dependent macromolecule catabolic processGO:0043632790.017
male gamete generationGO:00482322010.017
positive regulation of programmed cell deathGO:0043068620.017
embryonic axis specificationGO:00005781070.017
purine ribonucleoside metabolic processGO:00461281270.016
nucleobase containing small molecule metabolic processGO:00550861740.016
nucleobase containing compound catabolic processGO:00346551650.016
regulation of transportGO:00510491810.016
hematopoietic or lymphoid organ developmentGO:0048534570.016
regulation of protein metabolic processGO:00512462560.016
ribonucleoside metabolic processGO:00091191270.016
spermatogenesisGO:00072832000.016
organophosphate catabolic processGO:00464341120.016
cellular amine metabolic processGO:0044106120.016
rna processingGO:00063961470.016
purine containing compound catabolic processGO:00725231120.016
modification dependent protein catabolic processGO:0019941780.016
regulation of ras protein signal transductionGO:0046578930.016
guanosine containing compound catabolic processGO:1901069740.016
protein complex biogenesisGO:00702712010.016
phosphorylationGO:00163102940.016
negative regulation of gene expression epigeneticGO:0045814770.015
gtp metabolic processGO:0046039720.015
regulation of transcription from rna polymerase ii promoterGO:00063573780.015
phagocytosisGO:00069092150.015
regulation of nucleotide catabolic processGO:0030811480.015
regulation of mitotic cell cycle phase transitionGO:19019901300.015
digestive tract morphogenesisGO:00485461270.015
proteolysisGO:00065081920.014
protein ubiquitinationGO:0016567700.014
developmental growthGO:00485892800.014
regulation of cellular response to stressGO:0080135890.014
negative regulation of biosynthetic processGO:00098902770.014
regulation of catalytic activityGO:00507901850.014
positive regulation of transcription dna templatedGO:00458932660.014
purine ribonucleoside triphosphate catabolic processGO:00092071080.014
positive regulation of molecular functionGO:00440931360.014
nucleoside phosphate catabolic processGO:19012921100.014
ameboidal type cell migrationGO:00016671510.014
positive regulation of nucleotide catabolic processGO:0030813460.014
immune system developmentGO:0002520570.014
anterior posterior axis specification embryoGO:00085951030.014
mrna catabolic processGO:0006402330.014
glycosyl compound metabolic processGO:19016571270.014
cellular ketone metabolic processGO:0042180240.013
regulation of defense responseGO:00313471020.013
purine nucleoside triphosphate metabolic processGO:00091441190.013
actin cytoskeleton organizationGO:00300362060.013
regulation of peptidase activityGO:0052547390.013
spermatid differentiationGO:00485151140.013
regulation of neuron differentiationGO:00456641030.013
establishment of rna localizationGO:0051236470.013
positive regulation of ras gtpase activityGO:0032320360.013
response to oxygen containing compoundGO:19017002000.013
neurological system processGO:00508773580.013
regulation of phosphate metabolic processGO:00192202100.013
embryonic development via the syncytial blastodermGO:00017001480.012
negative regulation of mitotic cell cycleGO:00459301090.012
negative regulation of multicellular organismal processGO:00512411420.012
tube morphogenesisGO:00352391910.012
nucleoside phosphate metabolic processGO:00067531620.012
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.012
cell deathGO:00082192790.012
negative regulation of rna biosynthetic processGO:19026792400.012
regulation of molecular functionGO:00650092170.012
organelle fusionGO:0048284460.012
positive regulation of macromolecule biosynthetic processGO:00105572830.012
cell cycle phase transitionGO:00447701400.012
lipid metabolic processGO:00066291210.012
imaginal disc derived appendage developmentGO:00487373990.012
negative regulation of cell deathGO:0060548810.012
regulation of cellular amino acid metabolic processGO:000652100.012
anterior posterior pattern specificationGO:00099521360.012
regulation of protein localizationGO:0032880760.012
camera type eye developmentGO:004301040.011
ion homeostasisGO:0050801550.011
purine nucleoside catabolic processGO:00061521120.011
purine nucleoside metabolic processGO:00422781270.011
regulation of programmed cell deathGO:00430671520.011
decapentaplegic signaling pathwayGO:0008101190.011
central nervous system developmentGO:00074172010.011
regulation of ras gtpase activityGO:0032318380.011
eye developmentGO:00016543230.011
circadian rhythmGO:00076231050.011
peptidyl amino acid modificationGO:00181931050.011
vesicle localizationGO:0051648550.011
Mouse
tripartite regional subdivisionGO:00073511030.011
germarium derived egg chamber formationGO:00072931010.011
regulation of cell developmentGO:00602842150.011
compound eye developmentGO:00487493070.011
retina development in camera type eyeGO:006004140.011
metal ion transportGO:0030001740.011
chromatin organizationGO:00063252070.011
regulation of lipid storageGO:0010883220.011
cell proliferationGO:00082832990.011
respiratory system developmentGO:00605412130.011
peptidyl lysine modificationGO:0018205570.011
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.011
ribonucleoside triphosphate metabolic processGO:00091991190.011
regulation of endopeptidase activityGO:0052548360.011
regulation of organ morphogenesisGO:2000027780.011
mesenchymal cell developmentGO:001403110.011
negative regulation of transcription dna templatedGO:00458922370.011
cognitionGO:00508901410.010
pigment cell differentiationGO:005093130.010
epithelial cell migrationGO:00106311480.010
positive regulation of catalytic activityGO:00430851180.010
positive regulation of intracellular signal transductionGO:19025331160.010
positive regulation of rna metabolic processGO:00512542710.010
regulation of neuron projection developmentGO:0010975690.010
purine ribonucleotide metabolic processGO:00091501450.010
anion transportGO:0006820410.010
mitotic dna integrity checkpointGO:0044774750.010
positive regulation of rna biosynthetic processGO:19026802660.010
ribonucleoside triphosphate catabolic processGO:00092031080.010
proteolysis involved in cellular protein catabolic processGO:0051603830.010
chemosensory behaviorGO:00076351060.010
ras protein signal transductionGO:0007265880.010
nucleobase containing compound transportGO:0015931560.010

rb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.012