Drosophila melanogaster

124 known processes

Cka (Dmel_CG7392)

Connector of kinase to AP-1

(Aliases: 5836,CKA,l(2)s1883,CG7392,l(2)05836,Dmel\CG7392,anon-WO0172774.179,Dcka,anon-WO0172774.177,cka,anon-WO0172774.175,anon-WO0172774.174)

Cka biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
gravitaxisGO:0042332260.913
negative regulation of nucleobase containing compound metabolic processGO:00459342610.798
Human Rat
positive regulation of rna metabolic processGO:00512542710.793
Human
tissue morphogenesisGO:00487292970.773
morphogenesis of an epitheliumGO:00020092760.693
response to gravityGO:0009629260.633
regulation of cell developmentGO:00602842150.415
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.396
Human
positive regulation of macromolecule biosynthetic processGO:00105572830.360
Human
negative regulation of gene expressionGO:00106293870.286
Human Rat
regulation of cell proliferationGO:00421271630.279
negative regulation of nitrogen compound metabolic processGO:00511722650.274
Human Rat
negative regulation of rna metabolic processGO:00512532510.270
Human Rat
cellular protein modification processGO:00064644380.245
tube developmentGO:00352952440.239
negative regulation of response to stimulusGO:00485852580.232
Rat
taxisGO:00423303040.228
positive regulation of macromolecule metabolic processGO:00106044050.222
Human
regulation of transcription from rna polymerase ii promoterGO:00063573780.217
Human
embryonic morphogenesisGO:00485982060.215
digestive system developmentGO:00551231490.211
cell proliferationGO:00082832990.209
positive regulation of transcription dna templatedGO:00458932660.206
Human
negative regulation of cellular metabolic processGO:00313243820.195
Human Rat
dendrite morphogenesisGO:00488131990.193
response to abiotic stimulusGO:00096283410.184
embryo development ending in birth or egg hatchingGO:00097921520.179
eye developmentGO:00016543230.177
nucleocytoplasmic transportGO:0006913720.153
regulation of cell cycleGO:00517262910.151
appendage developmentGO:00487364010.150
embryonic development via the syncytial blastodermGO:00017001480.149
protein modification processGO:00362114380.143
regulation of multicellular organismal developmentGO:20000264140.143
regulation of organ morphogenesisGO:2000027780.143
antimicrobial humoral responseGO:0019730990.139
enzyme linked receptor protein signaling pathwayGO:00071671790.139
chromatin mediated maintenance of transcriptionGO:004809670.136
transcription from rna polymerase ii promoterGO:00063663680.133
Human
negative regulation of nucleic acid templated transcriptionGO:19035072400.133
Human Rat
agingGO:00075681430.133
cell deathGO:00082192790.132
regulation of localizationGO:00328792750.128
sensory organ morphogenesisGO:00905962600.127
cellular amide metabolic processGO:0043603800.124
growthGO:00400073590.123
cellular response to chemical stimulusGO:00708871990.122
organelle localizationGO:00516401480.122
cellular response to dna damage stimulusGO:00069742230.121
regulation of cellular response to stressGO:0080135890.115
response to other organismGO:00517072930.114
epithelial cell differentiationGO:00308553220.114
tube morphogenesisGO:00352391910.111
regulation of anatomical structure morphogenesisGO:00226032420.110
regulation of molecular functionGO:00650092170.109
imaginal disc derived appendage morphogenesisGO:00351143950.107
immune system processGO:00023763470.107
cell cell signaling involved in cell fate commitmentGO:00451682100.106
retina development in camera type eyeGO:006004140.106
morphogenesis of embryonic epitheliumGO:0016331940.097
dna repairGO:0006281540.096
organelle fissionGO:00482853400.093
regulation of cellular protein metabolic processGO:00322682430.093
positive regulation of biosynthetic processGO:00098913160.092
Human
dna metabolic processGO:00062592270.091
r7 cell differentiationGO:0045466430.090
negative regulation of intracellular signal transductionGO:1902532570.089
retina morphogenesis in camera type eyeGO:006004220.087
positive regulation of nucleobase containing compound metabolic processGO:00459353320.081
Human
phagocytosisGO:00069092150.080
imaginal disc derived appendage developmentGO:00487373990.080
negative regulation of rna biosynthetic processGO:19026792400.078
Human Rat
chromosome segregationGO:00070591570.074
regulation of neuron projection developmentGO:0010975690.071
positive regulation of signal transductionGO:00099672230.070
negative regulation of transcription dna templatedGO:00458922370.070
Human Rat
negative regulation of signal transductionGO:00099682060.070
Rat
negative regulation of cellular biosynthetic processGO:00313272770.069
Human Rat
cellular response to fibroblast growth factor stimulusGO:0044344100.067
chromosome organizationGO:00512763600.066
skin developmentGO:0043588650.065
appendage morphogenesisGO:00351073970.065
humoral immune responseGO:00069591170.065
chromatin remodelingGO:0006338720.064
positive regulation of cell proliferationGO:0008284470.061
positive regulation of nucleic acid templated transcriptionGO:19035082660.061
Human
double strand break repairGO:0006302260.060
organonitrogen compound metabolic processGO:19015643180.059
positive regulation of gene expressionGO:00106282900.058
Human
intracellular protein transportGO:00068861040.057
negative regulation of biosynthetic processGO:00098902770.057
Human Rat
digestive tract morphogenesisGO:00485461270.057
establishment of mitotic spindle localizationGO:0040001170.056
protein complex assemblyGO:00064612000.055
response to organic substanceGO:00100332840.055
Rat
positive regulation of cellular biosynthetic processGO:00313283160.054
Human
single organism intracellular transportGO:19025822070.054
chromatin modificationGO:00165681470.052
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.052
Human Rat
rna splicing via transesterification reactionsGO:0000375730.051
camera type eye developmentGO:004301040.051
gland developmentGO:00487321910.049
regulation of cell differentiationGO:00455953020.048
spindle organizationGO:00070512530.048
cell cycle phase transitionGO:00447701400.047
regulation of proteasomal protein catabolic processGO:0061136390.047
anatomical structure homeostasisGO:0060249970.047
eye photoreceptor cell fate commitmentGO:0042706370.047
regulation of neurogenesisGO:00507671580.046
eye photoreceptor cell differentiationGO:00017541450.046
single organism behaviorGO:00447083910.046
dendrite developmentGO:00163582040.045
Rat
establishment of localization in cellGO:00516494020.045
mitotic spindle organizationGO:00070522200.045
protein localizationGO:00081042840.044
respiratory system developmentGO:00605412130.044
embryonic hemopoiesisGO:0035162260.044
photoreceptor cell fate commitmentGO:0046552410.044
muscle cell fate commitmentGO:0042693140.043
digestive tract developmentGO:00485651490.043
photoreceptor cell differentiationGO:00465301700.043
developmental growthGO:00485892800.042
regulation of nervous system developmentGO:00519602480.042
regulation of embryonic developmentGO:0045995680.042
immune system developmentGO:0002520570.042
regulation of protein localizationGO:0032880760.042
endocytosisGO:00068973100.041
camera type eye morphogenesisGO:004859320.041
chemical homeostasisGO:0048878920.039
regulation of anatomical structure sizeGO:00900661630.039
compound eye photoreceptor developmentGO:0042051780.039
programmed cell deathGO:00125012570.039
compound eye morphogenesisGO:00017452490.039
response to biotic stimulusGO:00096072940.038
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.038
outflow tract morphogenesisGO:000315140.037
small molecule metabolic processGO:00442813050.037
regulation of protein metabolic processGO:00512462560.037
regulation of transportGO:00510491810.037
hematopoietic or lymphoid organ developmentGO:0048534570.037
axonogenesisGO:00074092900.036
cellular response to oxidative stressGO:0034599280.036
compound eye photoreceptor cell differentiationGO:00017511400.036
phototransductionGO:0007602520.036
macromolecular complex assemblyGO:00650032560.035
ion transmembrane transportGO:00342201220.035
imaginal disc growthGO:0007446370.035
columnar cuboidal epithelial cell differentiationGO:00020652560.034
imaginal disc derived wing morphogenesisGO:00074763370.034
periodic partitioningGO:0007365290.034
regulation of protein transportGO:0051223570.034
modification dependent macromolecule catabolic processGO:0043632790.033
regulation of programmed cell deathGO:00430671520.033
chromatin organizationGO:00063252070.032
developmental growth involved in morphogenesisGO:0060560650.032
single organism cellular localizationGO:19025801800.032
post embryonic appendage morphogenesisGO:00351203850.031
peptide metabolic processGO:0006518800.031
central nervous system developmentGO:00074172010.031
establishment of protein localizationGO:00451841630.031
negative regulation of macromolecule biosynthetic processGO:00105582700.031
Human Rat
defense responseGO:00069523000.031
spindle assemblyGO:0051225800.030
neuron fate commitmentGO:0048663500.030
regulation of cell cycle phase transitionGO:19019871300.030
positive regulation of nitrogen compound metabolic processGO:00511733540.030
Human
regulation of protein modification processGO:00313991120.029
cell type specific apoptotic processGO:0097285380.029
cell recognitionGO:00080371020.029
meiotic chromosome segregationGO:0045132590.029
regulation of mitotic cell cycleGO:00073461900.028
negative regulation of cell communicationGO:00106482230.028
Rat
protein modification by small protein conjugationGO:0032446790.028
positive regulation of rna biosynthetic processGO:19026802660.028
Human
anterior posterior pattern specificationGO:00099521360.027
nuclear divisionGO:00002803320.027
morphogenesis of a branching epitheliumGO:0061138450.027
eye morphogenesisGO:00485922600.027
signal transduction in response to dna damageGO:004277030.027
protein transportGO:00150311550.026
double strand break repair via homologous recombinationGO:0000724130.026
regulation of apoptotic processGO:00429811300.026
response to oxygen containing compoundGO:19017002000.026
Rat
actin filament based processGO:00300292200.026
antimicrobial peptide productionGO:0002775460.026
response to oxidative stressGO:0006979860.025
establishment of cell polarityGO:0030010400.025
establishment of spindle localizationGO:0051293220.025
defense response to other organismGO:00985422250.025
deathGO:00162652840.024
mitotic cell cycle embryonicGO:0045448380.024
regulation of epithelial cell differentiationGO:003085640.024
meiotic cell cycle processGO:19030461320.023
peptidyl amino acid modificationGO:00181931050.023
negative regulation of cellular protein metabolic processGO:0032269850.023
negative regulation of apoptotic processGO:0043066630.023
oxoacid metabolic processGO:00434361030.022
establishment or maintenance of cell polarityGO:00071631670.022
circulatory system developmentGO:0072359820.022
positive regulation of cell communicationGO:00106472500.022
positive regulation of phosphate metabolic processGO:00459371390.022
epidermal cell differentiationGO:0009913510.022
morphogenesis of a branching structureGO:0001763450.022
regulation of antimicrobial peptide biosynthetic processGO:0002805380.022
cell fate determinationGO:0001709910.022
homeostatic processGO:00425921990.022
centrosome organizationGO:00512971630.022
female sex differentiationGO:0046660200.021
development of primary sexual characteristicsGO:0045137500.021
Worm
reproductive system developmentGO:0061458740.021
Worm
dna templated transcription elongationGO:0006354180.021
regulation of gene silencingGO:0060968630.021
regulation of r7 cell differentiationGO:0045676150.021
positive regulation of transportGO:0051050920.021
response to bacteriumGO:00096171980.021
regulation of mitotic cell cycle phase transitionGO:19019901300.021
multi organism behaviorGO:00517051750.021
maintenance of locationGO:0051235730.020
regulation of i kappab kinase nf kappab signalingGO:004312220.020
positive regulation of molecular functionGO:00440931360.020
compound eye cone cell differentiationGO:0042675130.020
sister chromatid segregationGO:0000819920.020
regulation of neuron differentiationGO:00456641030.020
protein modification by small protein conjugation or removalGO:00706471060.019
photoreceptor cell developmentGO:0042461960.019
regulation of intracellular signal transductionGO:19025312360.019
nuclear transportGO:0051169720.019
eye antennal disc developmentGO:0035214600.019
negative regulation of cell developmentGO:0010721620.019
regulation of cell cycle processGO:00105641810.019
regulation of alternative mrna splicing via spliceosomeGO:0000381600.019
regulation of growthGO:00400082330.018
segmentationGO:00352822070.018
protein complex biogenesisGO:00702712010.018
positive regulation of signalingGO:00230562430.018
cellular response to organic substanceGO:00713101320.018
antennal developmentGO:0007469250.018
positive regulation of epithelial cell differentiationGO:003085810.018
intracellular transportGO:00469072280.018
development of primary female sexual characteristicsGO:0046545120.018
establishment of organelle localizationGO:00516561220.018
sex differentiationGO:0007548810.018
Worm
gene silencingGO:00164581380.018
regulation of dna templated transcription elongationGO:0032784170.017
response to fibroblast growth factorGO:0071774100.017
negative regulation of cell deathGO:0060548810.017
regulation of cellular amide metabolic processGO:0034248390.017
immune responseGO:00069552460.017
segment polarity determinationGO:0007367250.017
positive regulation of developmental processGO:00510941430.017
protein localization to nucleusGO:0034504550.017
regulation of lipid transportGO:003236830.017
amide biosynthetic processGO:0043604420.017
regulation of gene expression epigeneticGO:00400291280.017
gonad developmentGO:0008406500.017
Worm
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.017
Human
antibacterial peptide biosynthetic processGO:0002780220.017
dna alkylationGO:000630540.017
wnt signaling pathwayGO:0016055980.016
regulation of phosphorylationGO:00423251470.016
response to external biotic stimulusGO:00432072930.016
vesicle mediated transportGO:00161923810.016
wing disc morphogenesisGO:00074723440.016
positive regulation of immune system processGO:0002684680.016
chitin based cuticle developmentGO:0040003490.016
organonitrogen compound biosynthetic processGO:19015661170.016
adult behaviorGO:00305341370.016
neural retina developmentGO:000340740.016
exocrine system developmentGO:00352721620.016
cytoskeleton dependent cytokinesisGO:0061640810.016
positive regulation of gene expression epigeneticGO:0045815160.016
organ growthGO:0035265560.016
regulation of defense response to bacteriumGO:1900424300.015
cellular response to extracellular stimulusGO:0031668640.015
neurological system processGO:00508773580.015
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.015
intracellular signal transductionGO:00355563000.015
developmental programmed cell deathGO:00106231380.015
organic substance transportGO:00717022570.015
protein modification by small protein removalGO:0070646280.015
terminal region determinationGO:0007362250.015
axon guidanceGO:00074112330.015
mesenchymal cell developmentGO:001403110.015
compound eye retinal cell programmed cell deathGO:0046667230.015
protein targeting to nucleusGO:0044744510.015
negative regulation of molecular functionGO:0044092510.015
ameboidal type cell migrationGO:00016671510.015
mitotic cell cycle phase transitionGO:00447721380.014
metal ion transportGO:0030001740.014
regulation of dendrite morphogenesisGO:0048814280.014
signal transduction by phosphorylationGO:00230141070.014
actin cytoskeleton organizationGO:00300362060.014
regulation of cell projection organizationGO:0031344920.014
response to endogenous stimulusGO:00097191190.014
Rat
cell divisionGO:00513012480.014
positive regulation of response to stimulusGO:00485843230.014
carboxylic acid metabolic processGO:0019752920.014
skeletal muscle organ developmentGO:0060538480.014
reproductive structure developmentGO:0048608740.014
Worm
mitotic nuclear divisionGO:00070672130.014
mrna splicing via spliceosomeGO:0000398730.014
negative regulation of programmed cell deathGO:0043069720.014
mesenchymal cell differentiationGO:004876210.014
protein import into nucleusGO:0006606510.014
tissue deathGO:00162711020.014
positive regulation of multicellular organismal processGO:00512401430.014
proteolysisGO:00065081920.014
organic acid metabolic processGO:00060821030.014
chromatin silencingGO:0006342760.014
multicellular organismal agingGO:00102591400.014
regionalizationGO:00030024160.014
regulation of immune system processGO:00026821760.014
somatic stem cell divisionGO:0048103370.014
regulation of chromosome organizationGO:0033044640.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.013
neuron recognitionGO:00080381010.013
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.013
protein phosphorylationGO:00064681690.013
gastrulationGO:0007369700.013
protein acetylationGO:0006473390.013
olfactory behaviorGO:0042048970.013
chemotaxisGO:00069352490.013
regulation of antimicrobial humoral responseGO:0002759500.013
response to lipidGO:0033993380.013
Rat
instar larval developmentGO:0002168550.013
immune effector processGO:0002252980.013
regulation of embryonic cell shapeGO:0016476300.013
telencephalon developmentGO:002153720.013
regulation of cellular protein catabolic processGO:1903362440.012
localization of cellGO:00516742570.012
rna processingGO:00063961470.012
proteasomal protein catabolic processGO:0010498590.012
eye photoreceptor cell developmentGO:0042462810.012
stem cell differentiationGO:00488631170.012
epithelial tube morphogenesisGO:0060562880.012
salivary gland morphogenesisGO:00074351450.012
hair cell differentiationGO:0035315470.012
epithelial cell developmentGO:00020642740.012
phosphorylationGO:00163102940.012
regulation of establishment of protein localizationGO:0070201610.012
dorsal appendage formationGO:0046843470.012
blood circulationGO:0008015260.012
cytokinesisGO:0000910900.012
regulation of ion transmembrane transporter activityGO:003241260.012
negative regulation of protein metabolic processGO:0051248850.012
regulation of hydrolase activityGO:0051336970.011
modification dependent protein catabolic processGO:0019941780.011
ubiquitin dependent protein catabolic processGO:0006511780.011
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.011
negative regulation of r7 cell differentiationGO:004567720.011
secretionGO:00469031090.011
regulation of mrna splicing via spliceosomeGO:0048024640.011
hindbrain developmentGO:003090220.011
cellular protein catabolic processGO:0044257830.011
histolysisGO:00075591020.011
regulation of epithelial cell proliferationGO:005067840.011
cell junction assemblyGO:0034329420.011
antimicrobial peptide biosynthetic processGO:0002777380.011
myotube cell developmentGO:001490430.011
hemopoiesisGO:0030097460.011
lateral inhibitionGO:00463312060.011
microtubule cytoskeleton organization involved in mitosisGO:1902850520.011
negative regulation of catalytic activityGO:0043086420.011
negative regulation of response to external stimulusGO:0032102220.011
regulation of catalytic activityGO:00507901850.011
female meiotic divisionGO:0007143700.011
intracellular receptor signaling pathwayGO:0030522190.011
Rat
dorsal ventral axis specificationGO:0009950660.010
regulation of chromatin organizationGO:1902275320.010
larval developmentGO:00021641040.010
Worm
stem cell proliferationGO:0072089880.010
response to ecdysoneGO:0035075340.010
regulation of phosphorus metabolic processGO:00511742100.010
compound eye developmentGO:00487493070.010
synapse assemblyGO:00074161430.010
establishment of mitotic spindle orientationGO:0000132130.010
initiation of dorsal closureGO:0007392120.010
covalent chromatin modificationGO:00165691060.010
peptide biosynthetic processGO:0043043420.010
response to calcium ionGO:005159210.010
cell agingGO:000756920.010

Cka disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.016
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013
organ system cancerDOID:005068600.013