IMP: Integrative Multi-species Prediction

Drosophila melanogaster

75 known processes

CG9740 (Dmel_CG9740)

CG9740 gene product from transcript CG9740-RA

(Aliases: Dmel\CG9740)

Entrez: 41102
FLYBASE: FBgn0037669
UniProtKB: Q9VHG6

Process Predictions
Disease Predictions

CG9740 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.600
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.496
negative regulation of cellular biosynthetic process	GO:0031327	277	0.467
transcription from rna polymerase ii promoter	GO:0006366	368	0.434
positive regulation of rna biosynthetic process	GO:1902680	266	0.412
positive regulation of biosynthetic process	GO:0009891	316	0.377
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.376
chromosome organization	GO:0051276	360	0.376
negative regulation of transcription dna templated	GO:0045892	237	0.359
embryo development ending in birth or egg hatching	GO:0009792	152	0.325
negative regulation of rna biosynthetic process	GO:1902679	240	0.253
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.246
negative regulation of gene expression	GO:0010629	387	0.220
dna metabolic process	GO:0006259	227	0.189
positive regulation of cellular biosynthetic process	GO:0031328	316	0.170
positive regulation of rna metabolic process	GO:0051254	271	0.169
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.165
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.163
negative regulation of biosynthetic process	GO:0009890	277	0.153
chromatin organization	GO:0006325	207	0.146
regulation of cell differentiation	GO:0045595	302	0.146
establishment of localization in cell	GO:0051649	402	0.146
regulation of gene expression epigenetic	GO:0040029	128	0.144
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.142
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.137
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.125
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.121
positive regulation of macromolecule metabolic process	GO:0010604	405	0.117
positive regulation of gene expression	GO:0010628	290	0.114
rna splicing via transesterification reactions	GO:0000375	73	0.112
protein complex assembly	GO:0006461	200	0.110
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.105
macromolecular complex assembly	GO:0065003	256	0.104
cellular macromolecular complex assembly	GO:0034622	153	0.103
mrna splicing via spliceosome	GO:0000398	73	0.097
immune system process	GO:0002376	347	0.085
positive regulation of transcription dna templated	GO:0045893	266	0.082
dna conformation change	GO:0071103	105	0.081
organelle fission	GO:0048285	340	0.078
response to organic substance	GO:0010033	284	0.078
establishment or maintenance of cell polarity	GO:0007163	167	0.072
single organism behavior	GO:0044708	391	0.070
regulation of organelle organization	GO:0033043	196	0.070
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.067
rna splicing	GO:0008380	83	0.066
muscle structure development	GO:0061061	224	0.065
protein complex biogenesis	GO:0070271	201	0.063
nuclear division	GO:0000280	332	0.063
compound eye development	GO:0048749	307	0.062
sensory organ morphogenesis	GO:0090596	260	0.060
histone mrna metabolic process	GO:0008334	8	0.055
compound eye morphogenesis	GO:0001745	249	0.054
cytoplasmic transport	GO:0016482	130	0.053
vesicle mediated transport	GO:0016192	381	0.053
endocytosis	GO:0006897	310	0.051
regulation of gene silencing	GO:0060968	63	0.048
mrna processing	GO:0006397	104	0.046
response to biotic stimulus	GO:0009607	294	0.045
protein localization	GO:0008104	284	0.043
phagocytosis	GO:0006909	215	0.042
negative regulation of rna metabolic process	GO:0051253	251	0.042
intracellular transport	GO:0046907	228	0.041
trna transcription from rna polymerase iii promoter	GO:0042797	1	0.040
cellular component assembly involved in morphogenesis	GO:0010927	151	0.038
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.036
appendage morphogenesis	GO:0035107	397	0.034
nucleocytoplasmic transport	GO:0006913	72	0.033
regulation of chromatin organization	GO:1902275	32	0.032
gene silencing	GO:0016458	138	0.032
positive regulation of chromatin silencing	GO:0031937	16	0.030
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.030
dendrite development	GO:0016358	204	0.029
mrna metabolic process	GO:0016071	124	0.028
actin filament based process	GO:0030029	220	0.027
spindle organization	GO:0007051	253	0.027
regulation of multi organism process	GO:0043900	131	0.026
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.026
negative regulation of developmental process	GO:0051093	201	0.026
hematopoietic stem cell differentiation	GO:0060218	1	0.025
locomotory behavior	GO:0007626	176	0.025
rna processing	GO:0006396	147	0.024
leg disc morphogenesis	GO:0007478	80	0.024
photoreceptor cell differentiation	GO:0046530	170	0.024
regulation of chromatin silencing	GO:0031935	36	0.024
appendage development	GO:0048736	401	0.023
sex differentiation	GO:0007548	81	0.022
organic substance transport	GO:0071702	257	0.022
chromatin silencing	GO:0006342	76	0.021
positive regulation of defense response	GO:0031349	59	0.021
reproductive structure development	GO:0048608	74	0.021
regulation of multicellular organismal development	GO:2000026	414	0.021
chromatin remodeling	GO:0006338	72	0.021
negative regulation of cell differentiation	GO:0045596	143	0.020
eye morphogenesis	GO:0048592	260	0.020
chromatin assembly or disassembly	GO:0006333	52	0.019
regulation of cell cycle process	GO:0010564	181	0.018
imaginal disc derived appendage development	GO:0048737	399	0.018
gene silencing by rna	GO:0031047	57	0.017
centrosome organization	GO:0051297	163	0.017
regulation of chromatin modification	GO:1903308	28	0.017
regulation of cellular localization	GO:0060341	136	0.017
compound eye photoreceptor cell differentiation	GO:0001751	140	0.017
cellular response to chemical stimulus	GO:0070887	199	0.017
salivary gland morphogenesis	GO:0007435	145	0.016
central nervous system development	GO:0007417	201	0.016
response to other organism	GO:0051707	293	0.016
response to ketone	GO:1901654	34	0.016
regulation of dna templated transcription elongation	GO:0032784	17	0.016
regulation of protein metabolic process	GO:0051246	256	0.016
imaginal disc derived leg morphogenesis	GO:0007480	80	0.015
response to external biotic stimulus	GO:0043207	293	0.015
mitotic nuclear division	GO:0007067	213	0.015
cell proliferation	GO:0008283	299	0.015
positive regulation of signal transduction	GO:0009967	223	0.015
response to oxygen containing compound	GO:1901700	200	0.014
negative regulation of cellular metabolic process	GO:0031324	382	0.014
cellular response to organic substance	GO:0071310	132	0.014
positive regulation of lipid catabolic process	GO:0050996	1	0.014
gonad development	GO:0008406	50	0.014
mitotic spindle organization	GO:0007052	220	0.013
ribonucleoprotein complex disassembly	GO:0032988	1	0.013
chromosome segregation	GO:0007059	157	0.013
regulation of chromosome organization	GO:0033044	64	0.012
chromatin modification	GO:0016568	147	0.012
eye development	GO:0001654	323	0.012
regionalization	GO:0003002	416	0.012
regulation of cellular component biogenesis	GO:0044087	201	0.012
regulation of rac gtpase activity	GO:0032314	1	0.012
positive regulation of transcription from rna polymerase i promoter	GO:0045943	3	0.012
left right axis specification	GO:0070986	1	0.012
striated muscle myosin thick filament assembly	GO:0071688	3	0.011
dendrite morphogenesis	GO:0048813	199	0.011
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.011
chromatin assembly	GO:0031497	48	0.011
regulation of striated muscle contraction	GO:0006942	2	0.011
nitrogen compound transport	GO:0071705	85	0.011
small molecule metabolic process	GO:0044281	305	0.011
actin cytoskeleton organization	GO:0030036	206	0.011
adult behavior	GO:0030534	137	0.011
regulation of transport	GO:0051049	181	0.011
centrosome cycle	GO:0007098	137	0.010
response to organic cyclic compound	GO:0014070	89	0.010
regulation of cell cycle	GO:0051726	291	0.010
negative regulation of cell communication	GO:0010648	223	0.010
imaginal disc derived wing morphogenesis	GO:0007476	337	0.010
positive regulation of nurse cell apoptotic process	GO:0045850	5	0.010

CG9740 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.018
disease of anatomical entity	DOID:7	0.018
central nervous system disease	DOID:331	0.012
neurodegenerative disease	DOID:1289	0.011

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