Drosophila melanogaster

224 known processes

Crag (Dmel_CG12737)

Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein

(Aliases: CJ,Dmel\CG12737,CG12737,CRAG)

Crag biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell cycle phase transitionGO:19019871300.895
immune system processGO:00023763470.654
mitotic g2 dna damage checkpointGO:0007095690.634
regulation of mitotic cell cycle phase transitionGO:19019901300.603
regulation of notch signaling pathwayGO:00085931000.544
positive regulation of mrna catabolic processGO:006101450.538
notch signaling pathwayGO:00072191200.495
negative regulation of cell cycle phase transitionGO:19019881030.465
negative regulation of mitotic cell cycle phase transitionGO:19019911030.408
cell cycle checkpointGO:0000075950.396
negative regulation of mitotic cell cycleGO:00459301090.302
positive regulation of nucleobase containing compound metabolic processGO:00459353320.290
dna damage checkpointGO:0000077780.275
regulation of growthGO:00400082330.233
aromatic compound catabolic processGO:00194391660.213
rna catabolic processGO:0006401370.211
g2 dna damage checkpointGO:0031572690.208
negative regulation of cell cycle processGO:00109481090.207
mitotic g2 m transition checkpointGO:0044818700.206
asymmetric cell divisionGO:0008356370.201
cell cycle phase transitionGO:00447701400.201
cellular catabolic processGO:00442483720.191
mrna catabolic processGO:0006402330.181
regulation of cellular catabolic processGO:00313291570.178
catabolic processGO:00090564090.174
cellular response to dna damage stimulusGO:00069742230.169
single organism membrane fusionGO:0044801420.150
organic substance catabolic processGO:19015753080.150
endosomal transportGO:0016197440.149
establishment of organelle localizationGO:00516561220.142
endocytosisGO:00068973100.131
compound eye developmentGO:00487493070.130
epithelial cell developmentGO:00020642740.124
mitotic dna damage checkpointGO:0044773740.124
positive regulation of catabolic processGO:00098961050.116
negative regulation of immune system processGO:0002683500.112
lipid homeostasisGO:0055088330.111
mitotic cell cycle phase transitionGO:00447721380.105
regulation of mitotic cell cycleGO:00073461900.105
positive regulation of macromolecule metabolic processGO:00106044050.105
autophagyGO:00069141080.105
regulation of catabolic processGO:00098941700.104
regulation of small gtpase mediated signal transductionGO:0051056930.099
immune responseGO:00069552460.098
defense response to bacteriumGO:00427421780.098
intracellular signal transductionGO:00355563000.097
negative regulation of nitrogen compound metabolic processGO:00511722650.096
phototransduction visible lightGO:0007603270.093
protein modification by small protein removalGO:0070646280.092
macromolecule catabolic processGO:00090571610.092
pheromone biosynthetic processGO:004281130.091
mitotic cell cycle checkpointGO:0007093880.089
regulation of cell cycle processGO:00105641810.086
organic cyclic compound catabolic processGO:19013611680.085
positive regulation of transcription dna templatedGO:00458932660.084
response to endogenous stimulusGO:00097191190.084
positive regulation of rna metabolic processGO:00512542710.083
organic substance transportGO:00717022570.083
muscle structure developmentGO:00610612240.081
regulation of lamellipodium organizationGO:1902743150.081
nuclear transcribed mrna catabolic processGO:0000956240.079
regulation of cell cycle g1 s phase transitionGO:1902806230.076
negative regulation of cellular metabolic processGO:00313243820.072
membrane organizationGO:00610241120.069
dna integrity checkpointGO:0031570810.066
body morphogenesisGO:001017120.066
nucleobase containing small molecule metabolic processGO:00550861740.065
positive regulation of gene expressionGO:00106282900.065
positive regulation of signalingGO:00230562430.064
embryo development ending in birth or egg hatchingGO:00097921520.062
homeostatic processGO:00425921990.061
establishment or maintenance of bipolar cell polarityGO:0061245340.061
intracellular transportGO:00469072280.059
regulation of protein metabolic processGO:00512462560.058
oocyte axis specificationGO:00073091080.058
positive regulation of growthGO:0045927750.057
oocyte constructionGO:00073081120.056
growthGO:00400073590.056
larval developmentGO:00021641040.056
single organism biosynthetic processGO:00447112060.054
regulation of autophagyGO:0010506620.054
establishment of nucleus localizationGO:0040023260.053
synaptic transmissionGO:00072682880.053
regulation of cell proliferationGO:00421271630.052
positive regulation of cell communicationGO:00106472500.051
striated muscle myosin thick filament assemblyGO:007168830.051
positive regulation of nitrogen compound metabolic processGO:00511733540.050
negative regulation of growth of symbiont involved in interaction with hostGO:004414690.050
cell maturationGO:00484691440.050
response to abiotic stimulusGO:00096283410.049
regulation of lamellipodium assemblyGO:0010591150.048
mitotic dna integrity checkpointGO:0044774750.048
mrna metabolic processGO:00160711240.047
establishment of localization in cellGO:00516494020.047
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288140.046
transcription from rna polymerase ii promoterGO:00063663680.045
reproductive structure developmentGO:0048608740.044
cellular response to chemical stimulusGO:00708871990.044
multi organism behaviorGO:00517051750.044
cellular macromolecule catabolic processGO:00442651360.044
axis specificationGO:00097981670.043
negative regulation of response to stimulusGO:00485852580.043
positive regulation of signal transductionGO:00099672230.043
nucleobase containing compound catabolic processGO:00346551650.042
pigment metabolic processGO:0042440840.041
cellular ketone metabolic processGO:0042180240.041
hemopoiesisGO:0030097460.041
regulation of developmental growthGO:00486381740.041
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.040
heterocycle catabolic processGO:00467001660.040
organelle fissionGO:00482853400.039
head developmentGO:00603221350.039
sex differentiationGO:0007548810.038
sensory perception of soundGO:0007605560.038
translationGO:0006412690.038
vesicle mediated transportGO:00161923810.037
protein localizationGO:00081042840.036
oocyte developmentGO:00485991240.036
response to endoplasmic reticulum stressGO:0034976280.035
cell cell junction organizationGO:0045216550.035
positive regulation of cellular catabolic processGO:0031331950.035
regulation of immune system processGO:00026821760.035
regulation of multicellular organismal developmentGO:20000264140.034
anion homeostasisGO:005508130.034
positive regulation of nucleic acid templated transcriptionGO:19035082660.033
cell cycle g1 s phase transitionGO:0044843310.033
secretion by cellGO:00329401010.033
memoryGO:0007613940.032
positive regulation of phosphorus metabolic processGO:00105621390.032
positive regulation of cellular biosynthetic processGO:00313283160.032
establishment of mitochondrion localizationGO:005165470.032
phagocytosisGO:00069092150.032
regulation of purine nucleotide metabolic processGO:1900542620.032
dna repairGO:0006281540.031
ras protein signal transductionGO:0007265880.031
regulation of phosphate metabolic processGO:00192202100.031
positive regulation of developmental processGO:00510941430.031
nucleus localizationGO:0051647340.031
regulation of mrna 3 end processingGO:003144070.031
response to hypoxiaGO:0001666530.031
neuromuscular synaptic transmissionGO:0007274670.031
gland developmentGO:00487321910.031
small molecule metabolic processGO:00442813050.030
g1 s transition of mitotic cell cycleGO:0000082310.030
rna processingGO:00063961470.030
nucleoside phosphate metabolic processGO:00067531620.029
plasma membrane organizationGO:0007009260.029
nucleotide metabolic processGO:00091171610.029
response to oxygen levelsGO:0070482590.029
protein transportGO:00150311550.029
negative regulation of signal transductionGO:00099682060.028
negative regulation of gene expressionGO:00106293870.028
positive regulation of cell growthGO:0030307190.028
regulation of retinal cell programmed cell deathGO:0046668180.027
reproductive system developmentGO:0061458740.027
fatty acid homeostasisGO:005508920.027
protein localization to plasma membraneGO:0072659130.027
response to external biotic stimulusGO:00432072930.027
epithelial cell differentiationGO:00308553220.026
columnar cuboidal epithelial cell differentiationGO:00020652560.026
dna metabolic processGO:00062592270.026
regulation of response to stressGO:00801342000.026
establishment of protein localizationGO:00451841630.026
asymmetric protein localizationGO:0008105330.026
response to other organismGO:00517072930.025
establishment or maintenance of apical basal cell polarityGO:0035088340.025
negative regulation of cellular component organizationGO:00511291080.025
purine containing compound metabolic processGO:00725211550.025
cell proliferationGO:00082832990.024
positive regulation of nuclear transcribed mrna poly a tail shorteningGO:006021340.024
actin filament based processGO:00300292200.024
developmental growthGO:00485892800.024
regulation of phosphorus metabolic processGO:00511742100.024
positive regulation of biosynthetic processGO:00098913160.024
purine nucleoside metabolic processGO:00422781270.023
organophosphate catabolic processGO:00464341120.023
sensory perceptionGO:00076001960.023
cellular nitrogen compound catabolic processGO:00442701650.023
response to heatGO:0009408630.023
positive regulation of rna biosynthetic processGO:19026802660.023
organonitrogen compound metabolic processGO:19015643180.022
posttranscriptional regulation of gene expressionGO:00106081450.022
establishment or maintenance of cell polarityGO:00071631670.022
lipid metabolic processGO:00066291210.022
negative regulation of growthGO:0045926840.022
purine nucleotide metabolic processGO:00061631460.022
positive regulation of response to stimulusGO:00485843230.022
nuclear dna replicationGO:003326010.022
lipid catabolic processGO:0016042210.022
microtubule depolymerizationGO:0007019250.021
negative regulation of nucleic acid templated transcriptionGO:19035072400.021
cellular response to light stimulusGO:0071482370.021
exocytosisGO:0006887280.021
peptidyl lysine modificationGO:0018205570.021
regulation of epidermal cell differentiationGO:004560430.021
regulation of intracellular signal transductionGO:19025312360.021
organelle localizationGO:00516401480.020
single organism membrane organizationGO:0044802930.020
regulation of cytoplasmic transportGO:1903649470.020
response to uvGO:0009411240.020
nuclear divisionGO:00002803320.020
response to biotic stimulusGO:00096072940.020
regulation of multicellular organism growthGO:0040014400.020
negative regulation of synapse assemblyGO:0051964390.020
oxoacid metabolic processGO:00434361030.020
chromosome segregationGO:00070591570.019
rna transportGO:0050658460.019
secretionGO:00469031090.019
regulation of cell morphogenesis involved in differentiationGO:0010769610.019
purine nucleotide catabolic processGO:00061951090.019
eggshell chorion gene amplificationGO:000730790.019
regulation of cellular amine metabolic processGO:003323830.019
regulation of cell projection assemblyGO:0060491300.019
cellular response to sterol depletionGO:007150130.019
glycosyl compound catabolic processGO:19016581120.019
small gtpase mediated signal transductionGO:0007264880.019
cell junction organizationGO:0034330570.018
regulation of dendrite developmentGO:0050773370.018
endomembrane system organizationGO:00102561190.018
positive regulation of gtp catabolic processGO:0033126430.018
organelle fusionGO:0048284460.018
protein modification processGO:00362114380.018
negative regulation of cell cycleGO:00457861160.018
secondary metabolic processGO:0019748750.018
positive regulation of phosphate metabolic processGO:00459371390.018
cellular response to organic substanceGO:00713101320.018
actin cytoskeleton organizationGO:00300362060.017
negative regulation of signalingGO:00230572190.017
response to oxygen containing compoundGO:19017002000.017
cell growthGO:00160491080.017
multicellular organismal reproductive behaviorGO:00330571100.017
multicellular organism growthGO:0035264460.017
kidney developmentGO:000182230.017
regulation of cellular ketone metabolic processGO:001056530.017
positive regulation of cellular component organizationGO:00511301560.017
skin developmentGO:0043588650.017
guanosine containing compound catabolic processGO:1901069740.017
rna localizationGO:00064031150.017
cellular response to radiationGO:0071478520.016
glycosyl compound metabolic processGO:19016571270.016
ribonucleoside metabolic processGO:00091191270.016
brain developmentGO:00074201200.016
response to light stimulusGO:00094161240.016
regulation of cell cycleGO:00517262910.016
regulation of cellular response to stressGO:0080135890.016
peptidyl lysine methylationGO:0018022160.016
positive regulation of molecular functionGO:00440931360.016
cellular response to decreased oxygen levelsGO:0036294300.016
establishment of rna localizationGO:0051236470.015
ribonucleotide metabolic processGO:00092591450.015
single organism catabolic processGO:00447122280.015
purine ribonucleoside triphosphate catabolic processGO:00092071080.015
gtp catabolic processGO:0006184720.015
cognitionGO:00508901410.015
gene silencing by mirnaGO:0035195220.015
regulation of anatomical structure morphogenesisGO:00226032420.015
synaptic growth at neuromuscular junctionGO:00511241190.015
sterol homeostasisGO:005509240.015
eggshell formationGO:00307031050.015
regulation of nervous system developmentGO:00519602480.015
purine ribonucleoside metabolic processGO:00461281270.015
instar larval developmentGO:0002168550.015
purine nucleoside catabolic processGO:00061521120.015
defense responseGO:00069523000.015
compound eye retinal cell programmed cell deathGO:0046667230.015
forebrain developmentGO:003090020.014
defense response to other organismGO:00985422250.014
development of primary sexual characteristicsGO:0045137500.014
immune response regulating signaling pathwayGO:000276420.014
protein catabolic processGO:00301631010.014
nucleoside metabolic processGO:00091161270.014
immune system developmentGO:0002520570.014
cytoplasmic transportGO:00164821300.014
receptor recyclingGO:000188120.014
positive regulation of notch signaling pathwayGO:0045747340.014
leg disc developmentGO:0035218920.014
agingGO:00075681430.014
guanosine containing compound metabolic processGO:1901068740.014
cholesterol homeostasisGO:004263230.014
amine metabolic processGO:0009308120.014
regulation of g1 s transition of mitotic cell cycleGO:2000045230.014
negative regulation of organelle organizationGO:0010639560.014
maintenance of locationGO:0051235730.014
nucleobase containing compound transportGO:0015931560.014
larval midgut histolysisGO:0035069220.013
protein secretionGO:0009306450.013
single organism cellular localizationGO:19025801800.013
adult chitin containing cuticle pigmentationGO:0048085160.013
multicellular organismal homeostasisGO:0048871410.013
tissue deathGO:00162711020.013
response to extracellular stimulusGO:00099911160.013
developmental pigmentationGO:0048066680.013
gland morphogenesisGO:00226121450.013
oocyte differentiationGO:00099941450.013
negative regulation of developmental growthGO:0048640640.013
positive regulation of protein transportGO:0051222370.013
covalent chromatin modificationGO:00165691060.013
maintenance of cell polarityGO:0030011180.013
imaginal disc pattern formationGO:0007447910.013
response to decreased oxygen levelsGO:0036293580.013
carboxylic acid metabolic processGO:0019752920.012
intracellular mrna localizationGO:0008298660.012
establishment or maintenance of epithelial cell apical basal polarityGO:0045197240.012
multi multicellular organism processGO:00447061230.012
negative regulation of nucleobase containing compound metabolic processGO:00459342610.012
regulation of cell growthGO:0001558430.012
regulation of cell sizeGO:0008361630.012
meiotic cell cycleGO:00513211710.012
cellular response to abiotic stimulusGO:0071214580.012
activation of protein kinase activityGO:0032147120.012
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.012
nuclear transportGO:0051169720.012
carbohydrate derivative catabolic processGO:19011361180.012
ribose phosphate metabolic processGO:00196931450.012
cellular lipid catabolic processGO:0044242160.012
innate immune responseGO:00450871440.012
positive regulation of catalytic activityGO:00430851180.012
rna 3 end processingGO:0031123450.012
positive regulation of intracellular signal transductionGO:19025331160.012
compound eye morphogenesisGO:00017452490.012
response to bacteriumGO:00096171980.012
hindbrain developmentGO:003090220.012
negative regulation of transforming growth factor beta receptor signaling pathwayGO:003051240.012
regulation of catalytic activityGO:00507901850.012
phenol containing compound metabolic processGO:0018958570.012
morphogenesis of follicular epitheliumGO:0016333360.012
nitrogen compound transportGO:0071705850.011
lamellipodium assemblyGO:0030032210.011
sensory perception of mechanical stimulusGO:0050954720.011
tricarboxylic acid metabolic processGO:007235010.011
negative regulation of cellular biosynthetic processGO:00313272770.011
protein phosphorylationGO:00064681690.011
organonitrogen compound catabolic processGO:19015651280.011
ribonucleotide catabolic processGO:00092611090.011
organelle membrane fusionGO:0090174160.011
positive regulation of purine nucleotide catabolic processGO:0033123460.011
negative regulation of defense responseGO:0031348350.011
positive regulation of nucleotide catabolic processGO:0030813460.011
melanization defense responseGO:0035006450.011
epidermal cell differentiationGO:0009913510.011
response to organic cyclic compoundGO:0014070890.011
regulation of epithelial cell differentiationGO:003085640.011
positive regulation of macromolecule biosynthetic processGO:00105572830.011
positive regulation of multicellular organism growthGO:0040018210.011
oocyte microtubule cytoskeleton organizationGO:0016325350.011
gastrulation with mouth forming firstGO:0001703360.011
regulation of protein depolymerizationGO:1901879270.010
autophagic vacuole fusionGO:0000046150.010
organic hydroxy compound metabolic processGO:1901615830.010
salivary gland histolysisGO:0035070880.010

Crag disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
reproductive organ cancerDOID:19300.021
disease of cellular proliferationDOID:1456600.021
cancerDOID:16200.021
organ system cancerDOID:005068600.021
male reproductive organ cancerDOID:385600.021
central nervous system diseaseDOID:33100.013
nervous system diseaseDOID:86300.013
inherited metabolic disorderDOID:65500.011
disease of metabolismDOID:001466700.011