Drosophila melanogaster

5 known processes

Dhod (Dmel_CG9741)

Dihydroorotate dehydrogenase

(Aliases: l(3)s3512,DHOD,DHODH,CG9741,Dmel\CG9741,dhod)

Dhod biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
proteolysisGO:00065081920.389
negative regulation of mitotic cell cycle phase transitionGO:19019911030.282
intracellular transportGO:00469072280.235
single organism intracellular transportGO:19025822070.229
protein localizationGO:00081042840.226
regulation of cellular protein metabolic processGO:00322682430.214
cellular macromolecule localizationGO:00707272200.214
negative regulation of cellular metabolic processGO:00313243820.204
imaginal disc derived appendage morphogenesisGO:00351143950.184
cellular catabolic processGO:00442483720.182
posttranscriptional regulation of gene expressionGO:00106081450.170
establishment of localization in cellGO:00516494020.168
localization of cellGO:00516742570.166
regulation of cell cycle phase transitionGO:19019871300.150
regulation of mitotic cell cycleGO:00073461900.147
positive regulation of response to stimulusGO:00485843230.142
cellular protein catabolic processGO:0044257830.141
mitotic cell cycle checkpointGO:0007093880.131
cellular response to dna damage stimulusGO:00069742230.126
endocytosisGO:00068973100.125
regulation of translationGO:0006417560.124
proteolysis involved in cellular protein catabolic processGO:0051603830.119
cellular protein modification processGO:00064644380.111
intracellular protein transportGO:00068861040.111
cell motilityGO:00488702510.109
enzyme linked receptor protein signaling pathwayGO:00071671790.109
protein modification by small protein conjugation or removalGO:00706471060.105
cell migrationGO:00164772380.102
negative regulation of cell cycleGO:00457861160.101
regulation of protein metabolic processGO:00512462560.101
cellular macromolecule catabolic processGO:00442651360.100
vesicle mediated transportGO:00161923810.098
protein ubiquitinationGO:0016567700.096
organic substance transportGO:00717022570.096
macromolecule catabolic processGO:00090571610.092
protein modification processGO:00362114380.089
cellular protein localizationGO:00346131600.087
cell cycle checkpointGO:0000075950.084
negative regulation of cell cycle processGO:00109481090.082
apoptotic signaling pathwayGO:0097190270.082
protein transportGO:00150311550.081
regulation of phosphate metabolic processGO:00192202100.080
embryonic development via the syncytial blastodermGO:00017001480.080
regulation of localizationGO:00328792750.078
mitotic cell cycle phase transitionGO:00447721380.076
cell divisionGO:00513012480.076
intracellular signal transductionGO:00355563000.076
negative regulation of cell cycle phase transitionGO:19019881030.074
phagocytosisGO:00069092150.071
positive regulation of macromolecule metabolic processGO:00106044050.071
imaginal disc derived appendage developmentGO:00487373990.069
negative regulation of mitotic cell cycleGO:00459301090.068
regulation of intracellular signal transductionGO:19025312360.068
regulation of phosphorylationGO:00423251470.067
establishment of protein localizationGO:00451841630.067
macromolecular complex assemblyGO:00650032560.067
cellular amide metabolic processGO:0043603800.066
positive regulation of endopeptidase activityGO:0010950260.065
regulation of cell cycle processGO:00105641810.065
ubiquitin dependent protein catabolic processGO:0006511780.063
cellular response to chemical stimulusGO:00708871990.063
proteasomal protein catabolic processGO:0010498590.063
regulation of mitotic cell cycle phase transitionGO:19019901300.062
epidermal growth factor receptor signaling pathwayGO:0007173580.061
spermatid developmentGO:0007286980.059
protein localization to organelleGO:0033365820.059
regulation of phosphorus metabolic processGO:00511742100.059
cell proliferationGO:00082832990.058
regulation of cell cycleGO:00517262910.058
protein targetingGO:0006605640.058
regulation of cell deathGO:00109411730.057
regulation of cellular catabolic processGO:00313291570.057
spermatogenesisGO:00072832000.056
response to temperature stimulusGO:00092661060.055
response to organic substanceGO:00100332840.055
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.054
organelle assemblyGO:00709251980.054
cell growthGO:00160491080.053
deathGO:00162652840.053
appendage morphogenesisGO:00351073970.053
transmembrane transportGO:00550851390.052
negative regulation of signalingGO:00230572190.052
regulation of catalytic activityGO:00507901850.051
modification dependent macromolecule catabolic processGO:0043632790.050
catabolic processGO:00090564090.049
male gamete generationGO:00482322010.049
positive regulation of cell communicationGO:00106472500.049
cytoplasmic transportGO:00164821300.047
mitotic g2 m transition checkpointGO:0044818700.046
wing disc morphogenesisGO:00074723440.046
mitochondrion organizationGO:0007005650.045
negative regulation of cell communicationGO:00106482230.045
mapk cascadeGO:00001651070.045
organic substance catabolic processGO:19015753080.045
positive regulation of signalingGO:00230562430.044
mitotic dna integrity checkpointGO:0044774750.044
positive regulation of proteolysisGO:0045862520.044
cell cycle phase transitionGO:00447701400.044
establishment of protein localization to organelleGO:0072594620.043
positive regulation of signal transductionGO:00099672230.042
protein maturationGO:0051604710.042
regulation of mapk cascadeGO:0043408920.042
chromosome organizationGO:00512763600.041
segmentationGO:00352822070.041
post embryonic appendage morphogenesisGO:00351203850.041
growthGO:00400073590.041
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.041
negative regulation of response to stimulusGO:00485852580.040
response to oxidative stressGO:0006979860.040
modification dependent protein catabolic processGO:0019941780.039
dendrite developmentGO:00163582040.039
single organism cellular localizationGO:19025801800.039
phosphorylationGO:00163102940.038
programmed cell deathGO:00125012570.038
oxoacid metabolic processGO:00434361030.036
mitotic dna damage checkpointGO:0044773740.036
sex differentiationGO:0007548810.036
signal transduction by phosphorylationGO:00230141070.036
activation of cysteine type endopeptidase activityGO:0097202170.035
regulation of transcription from rna polymerase ii promoterGO:00063573780.034
apoptotic processGO:00069151590.034
cell deathGO:00082192790.034
regulation of molecular functionGO:00650092170.034
mitochondrial transportGO:000683980.034
cellular response to starvationGO:0009267610.033
positive regulation of molecular functionGO:00440931360.033
single organism biosynthetic processGO:00447112060.032
dna damage checkpointGO:0000077780.032
protein catabolic processGO:00301631010.031
positive regulation of cellular catabolic processGO:0031331950.031
translationGO:0006412690.031
peptide metabolic processGO:0006518800.030
epithelial cell differentiationGO:00308553220.030
endosomal transportGO:0016197440.030
sperm individualizationGO:0007291480.030
embryonic morphogenesisGO:00485982060.030
regulation of gene expression epigeneticGO:00400291280.030
regulation of dna metabolic processGO:0051052340.029
protein complex assemblyGO:00064612000.029
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.029
erbb signaling pathwayGO:0038127580.028
regulation of erbb signaling pathwayGO:1901184420.028
regionalizationGO:00030024160.028
positive regulation of catabolic processGO:00098961050.028
protein complex biogenesisGO:00702712010.028
appendage developmentGO:00487364010.027
regulation of proteolysisGO:0030162870.027
cellular response to extracellular stimulusGO:0031668640.026
imaginal disc derived wing morphogenesisGO:00074763370.025
ion transportGO:00068111450.025
response to starvationGO:0042594970.025
oocyte differentiationGO:00099941450.024
mitotic g2 dna damage checkpointGO:0007095690.024
immune system processGO:00023763470.024
positive regulation of cell deathGO:0010942690.024
positive regulation of cellular protein metabolic processGO:00322701180.023
somatic muscle developmentGO:0007525660.023
oocyte microtubule cytoskeleton polarizationGO:0008103220.023
heterocycle catabolic processGO:00467001660.023
g2 dna damage checkpointGO:0031572690.023
regulation of hydrolase activityGO:0051336970.023
regulation of organelle organizationGO:00330431960.023
response to abiotic stimulusGO:00096283410.023
cilium assemblyGO:0042384380.023
negative regulation of cellular protein metabolic processGO:0032269850.023
organonitrogen compound metabolic processGO:19015643180.022
cell agingGO:000756920.022
dorsal closureGO:0007391790.022
sperm axoneme assemblyGO:0007288130.022
positive regulation of lipid metabolic processGO:004583440.021
dna metabolic processGO:00062592270.021
negative regulation of cell deathGO:0060548810.021
positive regulation of catalytic activityGO:00430851180.021
developmental maturationGO:00217001720.021
regulation of programmed cell deathGO:00430671520.021
regulation of peptidase activityGO:0052547390.021
pigmentationGO:0043473750.021
regulation of multicellular organismal developmentGO:20000264140.021
response to endogenous stimulusGO:00097191190.020
positive regulation of biosynthetic processGO:00098913160.020
positive regulation of intracellular signal transductionGO:19025331160.020
positive regulation of phosphate metabolic processGO:00459371390.020
cation transportGO:00068121100.020
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.020
regulation of response to stressGO:00801342000.020
posttranscriptional gene silencingGO:0016441460.020
cilium morphogenesisGO:0060271390.020
organelle fissionGO:00482853400.020
negative regulation of erbb signaling pathwayGO:1901185290.020
negative regulation of phosphorus metabolic processGO:0010563450.020
protein phosphorylationGO:00064681690.020
nucleoside triphosphate metabolic processGO:00091411200.020
exocrine system developmentGO:00352721620.020
nucleobase containing compound catabolic processGO:00346551650.019
response to other organismGO:00517072930.019
protein k48 linked ubiquitinationGO:007093630.019
regulation of cellular component biogenesisGO:00440872010.019
dendrite morphogenesisGO:00488131990.019
negative regulation of catalytic activityGO:0043086420.019
regulation of catabolic processGO:00098941700.019
hematopoietic or lymphoid organ developmentGO:0048534570.018
intrinsic apoptotic signaling pathwayGO:0097193160.018
dna integrity checkpointGO:0031570810.018
mitotic spindle organizationGO:00070522200.018
nucleoside phosphate metabolic processGO:00067531620.018
protein transmembrane transportGO:007180640.018
protein processingGO:0016485680.018
nucleoside phosphate catabolic processGO:19012921100.018
regulation of protein localizationGO:0032880760.018
purine nucleotide metabolic processGO:00061631460.018
embryonic axis specificationGO:00005781070.018
small molecule metabolic processGO:00442813050.018
response to oxygen containing compoundGO:19017002000.017
negative regulation of protein metabolic processGO:0051248850.017
morphogenesis of an epitheliumGO:00020092760.017
positive regulation of phosphorus metabolic processGO:00105621390.017
reproductive system developmentGO:0061458740.017
regulation of proteasomal protein catabolic processGO:0061136390.017
positive regulation of hydrolase activityGO:0051345780.017
mitotic nuclear divisionGO:00070672130.017
negative regulation of programmed cell deathGO:0043069720.017
cellular homeostasisGO:0019725800.017
meiotic cell cycleGO:00513211710.016
embryonic pattern specificationGO:00098801740.016
embryo development ending in birth or egg hatchingGO:00097921520.016
negative regulation of signal transductionGO:00099682060.016
cellular response to nutrient levelsGO:0031669620.016
regulation of cell divisionGO:0051302720.016
aromatic compound catabolic processGO:00194391660.016
cellular nitrogen compound catabolic processGO:00442701650.016
negative regulation of phosphorylationGO:0042326350.016
negative regulation of protein modification processGO:0031400290.016
defense responseGO:00069523000.015
cellular amino acid metabolic processGO:0006520610.015
small gtpase mediated signal transductionGO:0007264880.015
regulation of autophagyGO:0010506620.015
rna processingGO:00063961470.015
ribosomal large subunit biogenesisGO:004227310.015
positive regulation of phosphorylationGO:0042327870.015
spindle organizationGO:00070512530.015
negative regulation of cellular component organizationGO:00511291080.015
ribonucleoside triphosphate catabolic processGO:00092031080.015
positive regulation of cell motilityGO:200014730.015
homeostatic processGO:00425921990.015
negative regulation of molecular functionGO:0044092510.015
regulation of cellular response to stressGO:0080135890.015
negative regulation of phosphate metabolic processGO:0045936450.015
negative regulation of protein phosphorylationGO:0001933170.015
secretion by cellGO:00329401010.015
ribonucleotide catabolic processGO:00092611090.015
response to nutrient levelsGO:00316671140.015
protein modification by small protein conjugationGO:0032446790.014
peptidyl amino acid modificationGO:00181931050.014
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.014
anterior posterior pattern specificationGO:00099521360.014
positive regulation of nucleobase containing compound metabolic processGO:00459353320.014
chemical homeostasisGO:0048878920.014
positive regulation of nitrogen compound metabolic processGO:00511733540.014
positive regulation of mapk cascadeGO:0043410630.014
taxisGO:00423303040.014
positive regulation of transcription dna templatedGO:00458932660.014
regulation of cell proliferationGO:00421271630.014
organophosphate metabolic processGO:00196371950.014
response to external biotic stimulusGO:00432072930.014
negative regulation of transcription dna templatedGO:00458922370.014
response to biotic stimulusGO:00096072940.014
cellular response to external stimulusGO:0071496660.014
sister chromatid segregationGO:0000819920.014
membrane organizationGO:00610241120.014
positive regulation of gene expressionGO:00106282900.014
axon midline choice point recognitionGO:0016199260.014
oocyte constructionGO:00073081120.014
atp metabolic processGO:0046034490.013
positive regulation of macromolecule biosynthetic processGO:00105572830.013
positive regulation of transportGO:0051050920.013
organophosphate catabolic processGO:00464341120.013
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.013
cellular response to oxygen containing compoundGO:1901701790.013
cellular macromolecular complex assemblyGO:00346221530.013
tissue migrationGO:00901301550.013
nephrocyte filtrationGO:009720670.013
protein localization to mitochondrionGO:007058510.013
negative regulation of cellular catabolic processGO:0031330340.013
transcription from rna polymerase ii promoterGO:00063663680.013
regulation of sister chromatid segregationGO:0033045280.013
regulation of cellular protein catabolic processGO:1903362440.013
rna localizationGO:00064031150.013
regulation of synapse structure and activityGO:00508031280.013
negative regulation of biosynthetic processGO:00098902770.012
purine containing compound metabolic processGO:00725211550.012
regulation of endopeptidase activityGO:0052548360.012
regulation of epithelial cell proliferationGO:005067840.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.012
spindle assemblyGO:0051225800.012
regulation of apoptotic processGO:00429811300.012
negative regulation of nucleic acid templated transcriptionGO:19035072400.012
defense response to other organismGO:00985422250.012
chaeta morphogenesisGO:0008407420.012
regulation of immune system processGO:00026821760.012
gene silencing by rnaGO:0031047570.012
zymogen activationGO:0031638200.012
gene silencingGO:00164581380.012
muscle structure developmentGO:00610612240.012
carbohydrate derivative catabolic processGO:19011361180.012
stress activated protein kinase signaling cascadeGO:0031098550.012
posttranscriptional gene silencing by rnaGO:0035194450.012
gonad developmentGO:0008406500.012
extrinsic apoptotic signaling pathwayGO:009719110.012
negative regulation of apoptotic processGO:0043066630.012
eye antennal disc developmentGO:0035214600.012
nuclear divisionGO:00002803320.012
columnar cuboidal epithelial cell differentiationGO:00020652560.012
induction of programmed cell death by ecdysoneGO:0035078120.012
actin filament based processGO:00300292200.012
positive regulation of rna metabolic processGO:00512542710.012
cell maturationGO:00484691440.012
cellular response to organic substanceGO:00713101320.012
sulfur compound metabolic processGO:0006790590.012
positive regulation of nucleic acid templated transcriptionGO:19035082660.012
retrograde transport endosome to golgiGO:004214730.012
molting cycle chitin based cuticleGO:0007591560.011
intracellular protein transmembrane transportGO:006500240.011
leg disc developmentGO:0035218920.011
tripartite regional subdivisionGO:00073511030.011
cell projection assemblyGO:0030031940.011
epithelial cell developmentGO:00020642740.011
positive regulation of i kappab kinase nf kappab signalingGO:004312310.011
regulation of protein phosphorylationGO:0001932640.011
axis specificationGO:00097981670.011
negative regulation of nucleobase containing compound metabolic processGO:00459342610.011
gland morphogenesisGO:00226121450.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.011
endomitotic cell cycleGO:000711370.011
regulation of protein catabolic processGO:0042176550.011
dna repairGO:0006281540.011
ion transmembrane transportGO:00342201220.011
autophagyGO:00069141080.011
developmental pigmentationGO:0048066680.011
purine ribonucleoside metabolic processGO:00461281270.011
response to dsrnaGO:0043331150.011
purine nucleoside metabolic processGO:00422781270.011
body morphogenesisGO:001017120.011
oocyte developmentGO:00485991240.011
wnt signaling pathwayGO:0016055980.011
regulation of cellular amine metabolic processGO:003323830.011
rrna processingGO:000636430.011
positive regulation of cellular biosynthetic processGO:00313283160.011
ras protein signal transductionGO:0007265880.010
purine ribonucleotide catabolic processGO:00091541090.010
positive regulation of apoptotic processGO:0043065470.010
nucleotide catabolic processGO:00091661090.010
positive regulation of apoptotic signaling pathwayGO:200123540.010
inorganic ion transmembrane transportGO:0098660730.010
immune responseGO:00069552460.010
development of primary sexual characteristicsGO:0045137500.010
single organism catabolic processGO:00447122280.010
camera type eye developmentGO:004301040.010
epithelium migrationGO:00901321480.010
humoral immune responseGO:00069591170.010
regulation of protein kinase activityGO:0045859510.010
cellularizationGO:0007349900.010
carbohydrate derivative metabolic processGO:19011352170.010

Dhod disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
nervous system diseaseDOID:86300.017
neurodegenerative diseaseDOID:128900.013
central nervous system diseaseDOID:33100.013
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
organ system cancerDOID:005068600.012
sensory system diseaseDOID:005015500.011