Drosophila melanogaster

114 known processes

spir (Dmel_CG10076)

spire

(Aliases: Spir,Dmel\CG10076,p150Spir,CG18621,Spire,l(2)08327,38C.34,38C.37,CG10076,p150-Spir)

spir biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oocyte developmentGO:00485991240.998
cell maturationGO:00484691440.997
oocyte differentiationGO:00099941450.991
oocyte anterior posterior axis specificationGO:0007314720.979
axis specificationGO:00097981670.975
chorion containing eggshell formationGO:00073041050.973
regulation of pole plasm oskar mrna localizationGO:0007317270.969
oocyte constructionGO:00073081120.953
oocyte axis specificationGO:00073091080.930
tripartite regional subdivisionGO:00073511030.927
cytoplasm organizationGO:0007028640.912
oocyte dorsal ventral axis specificationGO:0007310340.907
pole plasm rna localizationGO:0007316520.901
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.892
regionalizationGO:00030024160.873
embryonic axis specificationGO:00005781070.862
anterior posterior axis specification embryoGO:00085951030.859
embryonic pattern specificationGO:00098801740.845
anterior posterior axis specificationGO:00099481090.836
establishment of organelle localizationGO:00516561220.828
Human
actin filament based processGO:00300292200.818
regulation of oocyte developmentGO:0060281270.816
regulation of embryonic pattern specificationGO:1902875270.762
organelle localizationGO:00516401480.738
Human
ovarian follicle cell developmentGO:00307072480.718
regulation of cell maturationGO:1903429270.637
blastoderm segmentationGO:00073501590.632
pole plasm assemblyGO:0007315610.631
rna localizationGO:00064031150.594
columnar cuboidal epithelial cell differentiationGO:00020652560.588
maternal determination of anterior posterior axis embryoGO:0008358740.579
columnar cuboidal epithelial cell developmentGO:00020662490.571
developmental maturationGO:00217001720.551
segmentationGO:00352822070.532
dorsal ventral axis specificationGO:0009950660.516
meiotic cell cycle processGO:19030461320.490
Human
response to alcoholGO:0097305950.443
actin filament organizationGO:00070151260.421
meiotic cell cycleGO:00513211710.397
Human
pole plasm mrna localizationGO:0019094490.375
regulation of actin filament polymerizationGO:0030833250.368
regulation of protein polymerizationGO:0032271280.363
actin polymerization or depolymerizationGO:0008154310.336
regulation of embryonic developmentGO:0045995680.334
epithelial cell differentiationGO:00308553220.332
anterior posterior pattern specificationGO:00099521360.311
regulation of reproductive processGO:2000241540.304
meiotic chromosome segregationGO:0045132590.303
meiotic cytokinesisGO:0033206330.285
establishment of nucleus localizationGO:0040023260.271
pole plasm protein localizationGO:0007318100.262
intracellular mrna localizationGO:0008298660.209
oocyte microtubule cytoskeleton organizationGO:0016325350.208
regulation of cellular component biogenesisGO:00440872010.194
establishment of localization in cellGO:00516494020.168
Human
epithelial cell developmentGO:00020642740.168
actin cytoskeleton organizationGO:00300362060.166
nuclear divisionGO:00002803320.165
germarium derived oocyte fate determinationGO:0007294260.164
eggshell chorion assemblyGO:0007306660.164
dorsal ventral pattern formationGO:00099531330.159
localization of cellGO:00516742570.155
regulation of cellular component sizeGO:0032535980.148
chromosome localizationGO:0050000200.146
regulation of actin polymerization or depolymerizationGO:0008064270.144
regulation of actin filament lengthGO:0030832270.138
actin filament polymerizationGO:0030041270.128
regulation of actin filament based processGO:0032970420.127
eggshell formationGO:00307031050.126
female meiotic divisionGO:0007143700.124
regulation of anatomical structure sizeGO:00900661630.123
karyosome formationGO:0030717220.122
response to light stimulusGO:00094161240.117
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.114
chromosome segregationGO:00070591570.108
ethanolamine containing compound metabolic processGO:004243940.103
regulation of multicellular organismal developmentGO:20000264140.103
regulation of protein complex assemblyGO:0043254420.102
establishment or maintenance of cytoskeleton polarityGO:0030952440.100
cellularizationGO:0007349900.098
female meiosis chromosome segregationGO:0016321330.097
cellular component assembly involved in morphogenesisGO:00109271510.092
memoryGO:0007613940.087
nucleus localizationGO:0051647340.086
meiosis iGO:0007127590.085
cell migrationGO:00164772380.084
growthGO:00400073590.084
response to abiotic stimulusGO:00096283410.080
cytokinesisGO:0000910900.077
meiotic nuclear divisionGO:00071261510.075
positive regulation of actin filament polymerizationGO:0030838110.074
dorsal appendage formationGO:0046843470.072
oocyte localization involved in germarium derived egg chamber formationGO:0030720120.071
programmed cell deathGO:00125012570.068
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.068
chorion containing eggshell pattern formationGO:0030381110.067
organophosphate metabolic processGO:00196371950.067
g protein coupled receptor signaling pathwayGO:00071861360.066
macromolecular complex assemblyGO:00650032560.063
response to organic substanceGO:00100332840.063
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:003072260.060
response to oxidative stressGO:0006979860.059
behavioral response to ethanolGO:0048149490.058
gland developmentGO:00487321910.058
single organism biosynthetic processGO:00447112060.057
single organism behaviorGO:00447083910.056
ovarian fusome organizationGO:0030723110.056
oocyte maturationGO:000155630.055
axonogenesisGO:00074092900.054
organelle fissionGO:00482853400.053
protein complex assemblyGO:00064612000.052
oocyte fate determinationGO:0030716270.051
actin nucleationGO:004501080.050
fusome organizationGO:0045478130.049
nuclear migrationGO:0007097200.049
epithelial cell migrationGO:00106311480.049
regulation of cell projection organizationGO:0031344920.049
organophosphate biosynthetic processGO:0090407460.048
tissue deathGO:00162711020.047
chemical homeostasisGO:0048878920.046
tissue migrationGO:00901301550.045
regulation of epithelial cell differentiationGO:003085640.045
positive regulation of cellular response to insulin stimulusGO:190007840.043
actin filament bundle organizationGO:0061572280.043
cell divisionGO:00513012480.043
purine nucleotide metabolic processGO:00061631460.043
negative regulation of growthGO:0045926840.042
pole cell developmentGO:0007277260.042
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.040
vesicle mediated transportGO:00161923810.040
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.039
positive regulation of lipid metabolic processGO:004583440.038
regulation of cell cycleGO:00517262910.038
pole plasm oskar mrna localizationGO:0045451460.038
cellular amine metabolic processGO:0044106120.038
regulation of cellular localizationGO:00603411360.038
intracellular mrna localization involved in pattern specification processGO:0060810560.038
ribose phosphate biosynthetic processGO:0046390280.037
amine metabolic processGO:0009308120.037
lipid metabolic processGO:00066291210.035
cellular response to chemical stimulusGO:00708871990.035
regulation of localizationGO:00328792750.035
cognitionGO:00508901410.034
ovarian follicle cell migrationGO:00072971210.034
lipid biosynthetic processGO:0008610460.033
developmental growthGO:00485892800.031
acylglycerol biosynthetic processGO:004646320.031
taxisGO:00423303040.031
negative regulation of multicellular organismal processGO:00512411420.031
oocyte microtubule cytoskeleton polarizationGO:0008103220.030
male meiosisGO:0007140520.030
protein catabolic processGO:00301631010.029
camp biosynthetic processGO:0006171170.028
single organism cellular localizationGO:19025801800.028
Human
organonitrogen compound metabolic processGO:19015643180.028
cell growthGO:00160491080.027
single organism catabolic processGO:00447122280.027
detection of external stimulusGO:0009581660.026
phosphatidylcholine metabolic processGO:004647030.026
salivary gland histolysisGO:0035070880.026
membrane buddingGO:000690040.025
phosphorylationGO:00163102940.025
tissue morphogenesisGO:00487292970.025
spindle localizationGO:0051653220.025
Human
regulation of meiosisGO:004002030.025
cell proliferationGO:00082832990.025
positive regulation of organelle organizationGO:0010638650.024
establishment of spindle localizationGO:0051293220.024
Human
imaginal disc derived wing morphogenesisGO:00074763370.024
appendage morphogenesisGO:00351073970.024
catabolic processGO:00090564090.024
positive regulation of cellular component organizationGO:00511301560.023
salivary gland developmentGO:00074311620.023
regulation of synaptic growth at neuromuscular junctionGO:0008582890.023
regulation of multi organism processGO:00439001310.023
positive regulation of protein complex assemblyGO:0031334220.022
intercellular bridge organizationGO:0043063140.022
establishment or maintenance of cell polarityGO:00071631670.022
small molecule metabolic processGO:00442813050.022
response to nutrient levelsGO:00316671140.022
organonitrogen compound biosynthetic processGO:19015661170.021
positive regulation of response to stimulusGO:00485843230.021
intracellular transportGO:00469072280.021
positive regulation of cytoskeleton organizationGO:0051495210.021
organic substance catabolic processGO:19015753080.021
cellular protein complex assemblyGO:0043623710.021
regulation of synapse structure and activityGO:00508031280.021
generation of precursor metabolites and energyGO:0006091420.021
cytoskeleton dependent cytokinesisGO:0061640810.021
histolysisGO:00075591020.021
signal transduction by phosphorylationGO:00230141070.020
response to oxygen containing compoundGO:19017002000.020
imaginal disc derived appendage developmentGO:00487373990.019
regulation of epidermal cell differentiationGO:004560430.019
alcohol metabolic processGO:0006066250.019
pronuclear migrationGO:003504640.019
cellular response to oxygen containing compoundGO:1901701790.019
deathGO:00162652840.019
activation of mapk activityGO:000018790.019
regulation of phosphatase activityGO:001092130.019
regulation of synapse assemblyGO:0051963940.019
positive regulation of cell projection organizationGO:0031346290.019
regulation of cellular amine metabolic processGO:003323830.019
negative regulation of protein polymerizationGO:003227270.019
eye morphogenesisGO:00485922600.018
regulation of compound eye cone cell fate specificationGO:004268240.018
response to bacteriumGO:00096171980.018
carbohydrate derivative metabolic processGO:19011352170.018
organic cyclic compound catabolic processGO:19013611680.018
regulation of hemocyte proliferationGO:0035206370.017
determination of adult lifespanGO:00083401370.017
maternal specification of dorsal ventral axis oocyte germ line encodedGO:000731140.017
carbohydrate derivative biosynthetic processGO:1901137850.017
rna processingGO:00063961470.017
regulation of transportGO:00510491810.017
aromatic compound catabolic processGO:00194391660.016
sister chromatid segregationGO:0000819920.016
border follicle cell migrationGO:00072981130.016
positive regulation of macromolecule metabolic processGO:00106044050.016
intracellular signal transductionGO:00355563000.016
positive regulation of cell communicationGO:00106472500.016
nucleotide metabolic processGO:00091171610.016
protein transportGO:00150311550.016
apoptotic processGO:00069151590.015
purine ribonucleotide metabolic processGO:00091501450.015
response to gravityGO:0009629260.015
response to lipidGO:0033993380.015
positive regulation of phosphorylationGO:0042327870.015
establishment of spindle orientationGO:0051294180.015
oxoacid metabolic processGO:00434361030.015
negative regulation of actin filament polymerizationGO:003083770.015
glycerolipid metabolic processGO:0046486340.015
ion homeostasisGO:0050801550.015
single organism intracellular transportGO:19025822070.015
protein modification processGO:00362114380.015
metal ion transportGO:0030001740.015
gtp metabolic processGO:0046039720.014
regulation of cellular ketone metabolic processGO:001056530.014
nucleobase containing compound catabolic processGO:00346551650.014
ribonucleoside metabolic processGO:00091191270.014
forebrain developmentGO:003090020.014
cell motilityGO:00488702510.014
dendrite morphogenesisGO:00488131990.014
cystoblast divisionGO:0007282100.014
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.014
agingGO:00075681430.014
multicellular organismal agingGO:00102591400.013
regulation of antifungal peptide biosynthetic processGO:000281050.013
dna metabolic processGO:00062592270.013
developmental programmed cell deathGO:00106231380.013
germ cell migrationGO:0008354430.013
exocrine system developmentGO:00352721620.013
positive regulation of signalingGO:00230562430.013
organic substance transportGO:00717022570.013
response to oxygen levelsGO:0070482590.013
protein localizationGO:00081042840.013
cellular response to biotic stimulusGO:007121640.013
organic acid metabolic processGO:00060821030.013
endodermal cell fate commitmentGO:000171130.013
negative regulation of cellular component organizationGO:00511291080.013
mitotic sister chromatid segregationGO:0000070870.013
cellular response to organic cyclic compoundGO:0071407320.013
dendrite developmentGO:00163582040.012
mapk cascadeGO:00001651070.012
cyclic nucleotide metabolic processGO:0009187280.012
immune response activating signal transductionGO:000275720.012
synaptic growth at neuromuscular junctionGO:00511241190.012
lipid homeostasisGO:0055088330.012
endocytosisGO:00068973100.012
cellular amino acid metabolic processGO:0006520610.012
cellular ketone metabolic processGO:0042180240.012
chemotaxisGO:00069352490.012
regulation of small gtpase mediated signal transductionGO:0051056930.012
regulation of insulin secretionGO:005079650.011
negative regulation of oskar mrna translationGO:000731950.011
positive regulation of lipid biosynthetic processGO:004688930.011
ribonucleotide metabolic processGO:00092591450.011
response to decreased oxygen levelsGO:0036293580.011
regulation of stress activated protein kinase signaling cascadeGO:0070302420.011
detection of stimulus involved in sensory perceptionGO:0050906920.011
nucleobase containing small molecule metabolic processGO:00550861740.011
synaptic transmissionGO:00072682880.011
molting cycleGO:0042303560.011
positive regulation of catabolic processGO:00098961050.011
leg disc morphogenesisGO:0007478800.011
positive regulation of macromolecule biosynthetic processGO:00105572830.011
positive regulation of gene expressionGO:00106282900.011
membrane organizationGO:00610241120.010
nucleoside phosphate metabolic processGO:00067531620.010
regulation of phosphate metabolic processGO:00192202100.010
regulation of cell morphogenesisGO:00226041630.010
embryonic morphogenesisGO:00485982060.010
purine ribonucleoside catabolic processGO:00461301120.010
actin filament bundle assemblyGO:0051017260.010
regulation of purine nucleotide metabolic processGO:1900542620.010
regulation of cellular amino acid metabolic processGO:000652100.010

spir disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.164
nervous system diseaseDOID:86300.027
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014