Drosophila melanogaster

0 known processes

Psa (Dmel_CG1009)

Puromycin sensitive aminopeptidase

(Aliases: dPsa,CG1009,PSA,Dmel\CG1009,dPSA,l(3)06226)

Psa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein modification by small protein conjugation or removalGO:00706471060.249
cellular macromolecule catabolic processGO:00442651360.241
segmentationGO:00352822070.233
proteolysisGO:00065081920.229
proteolysis involved in cellular protein catabolic processGO:0051603830.211
anterior posterior axis specificationGO:00099481090.190
protein ubiquitinationGO:0016567700.168
modification dependent macromolecule catabolic processGO:0043632790.142
posttranscriptional regulation of gene expressionGO:00106081450.139
protein modification by small protein conjugationGO:0032446790.129
regulation of cellular protein metabolic processGO:00322682430.129
intracellular signal transductionGO:00355563000.126
regulation of pole plasm oskar mrna localizationGO:0007317270.121
ubiquitin dependent protein catabolic processGO:0006511780.121
cellular protein catabolic processGO:0044257830.111
regulation of cellular component biogenesisGO:00440872010.109
catabolic processGO:00090564090.107
pole plasm mrna localizationGO:0019094490.102
macromolecule catabolic processGO:00090571610.102
protein catabolic processGO:00301631010.098
cellular protein modification processGO:00064644380.096
modification dependent protein catabolic processGO:0019941780.092
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.090
positive regulation of macromolecule metabolic processGO:00106044050.089
protein modification processGO:00362114380.086
phosphorylationGO:00163102940.085
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.084
sperm individualizationGO:0007291480.083
cellular macromolecule localizationGO:00707272200.082
mapk cascadeGO:00001651070.081
regulation of transcription from rna polymerase ii promoterGO:00063573780.076
cellular catabolic processGO:00442483720.075
organic substance catabolic processGO:19015753080.075
positive regulation of response to stimulusGO:00485843230.074
regulation of protein metabolic processGO:00512462560.072
mitotic cytokinesisGO:0000281500.070
lateral inhibitionGO:00463312060.069
protein maturationGO:0051604710.064
cellularizationGO:0007349900.062
oocyte constructionGO:00073081120.062
oocyte differentiationGO:00099941450.061
oocyte microtubule cytoskeleton polarizationGO:0008103220.060
translationGO:0006412690.060
negative regulation of macromolecule biosynthetic processGO:00105582700.060
regulation of multicellular organismal developmentGO:20000264140.059
proteasomal protein catabolic processGO:0010498590.052
positive regulation of signal transductionGO:00099672230.052
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.050
protein complex biogenesisGO:00702712010.049
positive regulation of gene expressionGO:00106282900.048
regulation of nf kappab import into nucleusGO:004234510.047
intracellular protein transmembrane transportGO:006500240.046
immune effector processGO:0002252980.046
tissue morphogenesisGO:00487292970.042
apoptotic processGO:00069151590.042
negative regulation of cellular metabolic processGO:00313243820.042
cell divisionGO:00513012480.042
regulation of programmed cell deathGO:00430671520.041
oocyte dorsal ventral axis specificationGO:0007310340.041
pole plasm rna localizationGO:0007316520.041
intracellular transportGO:00469072280.041
oocyte anterior posterior axis specificationGO:0007314720.041
agingGO:00075681430.040
imaginal disc derived wing morphogenesisGO:00074763370.040
nephron developmentGO:007200630.040
oocyte axis specificationGO:00073091080.039
chromosome organizationGO:00512763600.039
protein transportGO:00150311550.038
connective tissue developmentGO:006144830.038
cytoskeleton dependent cytokinesisGO:0061640810.037
regulation of cell deathGO:00109411730.037
cytokinesisGO:0000910900.037
muscle organ developmentGO:00075171270.037
cellular amide metabolic processGO:0043603800.035
protein processingGO:0016485680.035
regulation of organ morphogenesisGO:2000027780.035
regulation of synapse structure and activityGO:00508031280.035
regulation of reproductive processGO:2000241540.035
oocyte developmentGO:00485991240.035
multicellular organismal agingGO:00102591400.034
determination of dorsal ventral asymmetryGO:004826230.034
endocytosisGO:00068973100.033
cellular macromolecular complex assemblyGO:00346221530.033
maternal determination of anterior posterior axis embryoGO:0008358740.032
chromosome separationGO:0051304420.032
axis specificationGO:00097981670.032
protein transmembrane transportGO:007180640.030
muscle structure developmentGO:00610612240.030
negative regulation of gene expressionGO:00106293870.030
single organism cellular localizationGO:19025801800.030
protein deubiquitinationGO:0016579170.030
pole plasm assemblyGO:0007315610.029
tripartite regional subdivisionGO:00073511030.029
embryonic morphogenesisGO:00485982060.029
regulation of multi organism processGO:00439001310.029
larval developmentGO:00021641040.028
regulation of mrna 3 end processingGO:003144070.028
response to abiotic stimulusGO:00096283410.028
regulation of proteolysisGO:0030162870.028
macromolecular complex assemblyGO:00650032560.028
compound eye developmentGO:00487493070.027
positive regulation of cellular protein metabolic processGO:00322701180.027
regulation of metaphase anaphase transition of cell cycleGO:1902099260.027
imaginal disc derived appendage developmentGO:00487373990.027
response to bacteriumGO:00096171980.027
cell cell signaling involved in cell fate commitmentGO:00451682100.027
protein complex assemblyGO:00064612000.027
embryonic pattern specificationGO:00098801740.026
positive regulation of nitrogen compound metabolic processGO:00511733540.026
oxoacid metabolic processGO:00434361030.026
positive regulation of mapk cascadeGO:0043410630.025
vesicle mediated transportGO:00161923810.025
developmental maturationGO:00217001720.024
pigmentationGO:0043473750.024
cytoplasm organizationGO:0007028640.024
regionalizationGO:00030024160.024
negative regulation of biosynthetic processGO:00098902770.023
intracellular mrna localization involved in pattern specification processGO:0060810560.023
dorsal ventral pattern formationGO:00099531330.023
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.023
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.023
rna localizationGO:00064031150.022
positive regulation of signalingGO:00230562430.022
rna processingGO:00063961470.022
negative regulation of cell cycle phase transitionGO:19019881030.022
embryonic axis specificationGO:00005781070.022
molting cycleGO:0042303560.021
deathGO:00162652840.021
positive regulation of intracellular signal transductionGO:19025331160.021
oocyte microtubule cytoskeleton organizationGO:0016325350.021
determination of adult lifespanGO:00083401370.021
establishment of body hair planar orientationGO:004810510.021
regulation of peptidase activityGO:0052547390.021
mitochondrion organizationGO:0007005650.021
cell maturationGO:00484691440.021
defense response to other organismGO:00985422250.021
regulation of embryonic pattern specificationGO:1902875270.021
response to organic substanceGO:00100332840.021
cellular component assembly involved in morphogenesisGO:00109271510.021
positive regulation of cellular biosynthetic processGO:00313283160.020
regulation of cell cycleGO:00517262910.020
imaginal disc derived appendage morphogenesisGO:00351143950.020
positive regulation of mrna processingGO:005068540.020
positive regulation of nucleobase containing compound metabolic processGO:00459353320.020
peptide metabolic processGO:0006518800.020
protein modification by small protein removalGO:0070646280.020
regulation of protein complex assemblyGO:0043254420.020
transition metal ion transportGO:0000041160.019
transcription from rna polymerase ii promoterGO:00063663680.019
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.019
negative regulation of erbb signaling pathwayGO:1901185290.019
mushroom body developmentGO:0016319700.019
negative regulation of response to stimulusGO:00485852580.019
gland developmentGO:00487321910.019
anterior posterior axis specification embryoGO:00085951030.019
regulation of defense response to bacteriumGO:1900424300.019
establishment of protein localizationGO:00451841630.019
growthGO:00400073590.018
regulation of apoptotic processGO:00429811300.018
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.018
establishment or maintenance of cytoskeleton polarityGO:0030952440.018
negative regulation of cell deathGO:0060548810.018
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.018
positive regulation of cellular component organizationGO:00511301560.018
intracellular mrna localizationGO:0008298660.018
nf kappab import into nucleusGO:004234810.018
response to external biotic stimulusGO:00432072930.018
negative regulation of protein processingGO:0010955310.018
nuclear transcribed mrna poly a tail shorteningGO:0000289120.018
nuclear transcribed mrna catabolic processGO:0000956240.018
rna interferenceGO:0016246270.018
small molecule metabolic processGO:00442813050.017
spermatid developmentGO:0007286980.017
blastoderm segmentationGO:00073501590.017
regulation of mrna metabolic processGO:1903311720.017
morphogenesis of embryonic epitheliumGO:0016331940.017
carboxylic acid metabolic processGO:0019752920.017
forebrain developmentGO:003090020.017
intracellular protein transportGO:00068861040.017
nucleobase containing compound catabolic processGO:00346551650.017
regulation of response to stressGO:00801342000.017
post embryonic appendage morphogenesisGO:00351203850.017
organonitrogen compound metabolic processGO:19015643180.017
epithelial cell differentiationGO:00308553220.017
positive regulation of cell communicationGO:00106472500.017
embryo development ending in birth or egg hatchingGO:00097921520.017
pole plasm oskar mrna localizationGO:0045451460.017
regulation of intracellular signal transductionGO:19025312360.016
organic substance transportGO:00717022570.016
protein targetingGO:0006605640.016
mrna catabolic processGO:0006402330.016
regulation of nuclear transcribed mrna poly a tail shorteningGO:006021140.016
regulation of chromosome organizationGO:0033044640.016
regulation of epithelial cell differentiationGO:003085640.016
regulation of r7 cell differentiationGO:0045676150.016
establishment of localization in cellGO:00516494020.016
negative regulation of protein metabolic processGO:0051248850.016
atp metabolic processGO:0046034490.016
regulation of mitotic sister chromatid segregationGO:0033047280.016
positive regulation of biosynthetic processGO:00098913160.016
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.016
hair cell differentiationGO:0035315470.015
nephron tubule morphogenesisGO:007207830.015
regulation of cell cycle processGO:00105641810.015
immune system processGO:00023763470.015
organic cyclic compound catabolic processGO:19013611680.015
body morphogenesisGO:001017120.015
terminal region determinationGO:0007362250.015
positive regulation of mrna catabolic processGO:006101450.015
negative regulation of developmental processGO:00510932010.015
response to dsrnaGO:0043331150.015
kidney epithelium developmentGO:007207330.015
regulation of phosphorylationGO:00423251470.015
response to oxidative stressGO:0006979860.015
regulation of cell differentiationGO:00455953020.015
mitotic sister chromatid segregationGO:0000070870.015
response to biotic stimulusGO:00096072940.015
regulation of cellular protein catabolic processGO:1903362440.015
embryonic development via the syncytial blastodermGO:00017001480.015
skin developmentGO:0043588650.015
mrna processingGO:00063971040.014
germline ring canal formationGO:0030725130.014
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.014
cellular nitrogen compound catabolic processGO:00442701650.014
appendage segmentationGO:0035285260.014
protein localizationGO:00081042840.014
positive regulation of cell deathGO:0010942690.014
aromatic compound catabolic processGO:00194391660.014
organic acid metabolic processGO:00060821030.014
stem cell developmentGO:0048864790.014
regulation of chromosome segregationGO:0051983320.014
head developmentGO:00603221350.014
protein polymerizationGO:0051258420.014
compound eye photoreceptor cell differentiationGO:00017511400.014
regulation of localizationGO:00328792750.014
immune responseGO:00069552460.013
compound eye morphogenesisGO:00017452490.013
sister chromatid segregationGO:0000819920.013
negative regulation of programmed cell deathGO:0043069720.013
posttranscriptional gene silencingGO:0016441460.013
regulation of protein modification by small protein conjugation or removalGO:1903320250.013
negative regulation of nucleobase containing compound metabolic processGO:00459342610.013
regulation of establishment of planar polarityGO:0090175220.013
establishment of protein localization to organelleGO:0072594620.013
regulation of i kappab kinase nf kappab signalingGO:004312220.013
appendage morphogenesisGO:00351073970.013
regulation of translationGO:0006417560.013
cellular response to ethanolGO:007136140.013
regulation of protein catabolic processGO:0042176550.013
positive regulation of mrna 3 end processingGO:003144240.013
production of small rna involved in gene silencing by rnaGO:0070918150.013
epidermal cell differentiationGO:0009913510.013
determination of ventral identityGO:004826410.013
anterior posterior pattern specificationGO:00099521360.013
imaginal disc derived leg segmentationGO:0036011260.013
limb morphogenesisGO:003510810.013
cellular protein complex assemblyGO:0043623710.013
regulation of chitin based cuticle tanningGO:0007564140.013
regulation of anatomical structure sizeGO:00900661630.012
regulation of organelle organizationGO:00330431960.012
mitochondrion morphogenesisGO:007058480.012
imaginal disc pattern formationGO:0007447910.012
er associated ubiquitin dependent protein catabolic processGO:003043330.012
cell deathGO:00082192790.012
regulation of histone deacetylationGO:003106320.012
response to radiationGO:00093141550.012
regulation of mapk cascadeGO:0043408920.012
negative regulation of proteolysisGO:0045861310.012
nephron morphogenesisGO:007202830.012
signal transduction by phosphorylationGO:00230141070.012
kidney morphogenesisGO:006099330.012
regulation of phosphorus metabolic processGO:00511742100.012
mitotic cell cycle phase transitionGO:00447721380.012
equator specificationGO:004531740.012
cellular response to organic substanceGO:00713101320.012
imaginal disc derived wing vein specificationGO:0007474480.012
negative regulation of cellular biosynthetic processGO:00313272770.012
heterocycle catabolic processGO:00467001660.012
purine nucleotide metabolic processGO:00061631460.011
somatic muscle developmentGO:0007525660.011
gland morphogenesisGO:00226121450.011
retina development in camera type eyeGO:006004140.011
positive regulation of catabolic processGO:00098961050.011
negative regulation of mitotic cell cycle phase transitionGO:19019911030.011
regulation of proteasomal protein catabolic processGO:0061136390.011
unidimensional cell growthGO:0009826150.011
regulation of cell divisionGO:0051302720.011
wing disc morphogenesisGO:00074723440.011
neuron projection guidanceGO:00974852410.011
cuticle pigmentationGO:0048067220.011
regulation of sister chromatid segregationGO:0033045280.011
regulation of response to biotic stimulusGO:0002831630.011
spermatid differentiationGO:00485151140.011
peripheral nervous system developmentGO:0007422520.011
necrotic cell deathGO:007026510.011
nucleotide metabolic processGO:00091171610.011
response to lipopolysaccharideGO:003249640.011
membrane buddingGO:000690040.011
negative regulation of cell differentiationGO:00455961430.011
regulation of immune system processGO:00026821760.011
cell agingGO:000756920.011
regulation of protein modification processGO:00313991120.011
regulation of cell developmentGO:00602842150.011
muscle cell differentiationGO:00426921030.010
regulation of synapse organizationGO:00508071100.010
molting cycle chitin based cuticleGO:0007591560.010
mesenchymal cell differentiationGO:004876210.010
negative regulation of endopeptidase activityGO:0010951110.010
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051170.010
cell proliferationGO:00082832990.010
regulation of cellular amine metabolic processGO:003323830.010
single organism membrane fusionGO:0044801420.010
cellular amine metabolic processGO:0044106120.010
membrane organizationGO:00610241120.010
phagocytosisGO:00069092150.010
gene silencing by rnaGO:0031047570.010
nucleoside phosphate metabolic processGO:00067531620.010
negative regulation of mitotic cell cycleGO:00459301090.010

Psa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
nervous system diseaseDOID:86300.027
neurodegenerative diseaseDOID:128900.027
motor neuron diseaseDOID:23100.027
central nervous system diseaseDOID:33100.027
cardiovascular system diseaseDOID:128700.015
sensory system diseaseDOID:005015500.010
autosomal dominant nonsyndromic deafnessDOID:005056400.010
auditory system diseaseDOID:274200.010
nonsyndromic deafnessDOID:005056300.010