Drosophila melanogaster

0 known processes

Pak (Dmel_CG10295)

PAK-kinase

(Aliases: DPak,dPAK,PaK,pak1,pak,D-Pak,p65[PAK],Dpak1,CG10295,Dmel\CG10295,Pak1,DPAK,dPAK1,dpak,PAK2,Dpak,dPak,PAK,dpak1,PAK1,DmPAK1)

Pak biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
axonogenesisGO:00074092900.998
Mouse
regulation of nervous system developmentGO:00519602480.992
Rat Fly
regulation of synaptic growth at neuromuscular junctionGO:0008582890.988
chemotaxisGO:00069352490.986
axon developmentGO:00615642970.979
Mouse
establishment of localization in cellGO:00516494020.976
Yeast
developmental growth involved in morphogenesisGO:0060560650.975
synaptic growth at neuromuscular junctionGO:00511241190.974
taxisGO:00423303040.946
neuromuscular junction developmentGO:00075281490.922
Mouse
regulation of neurogenesisGO:00507671580.907
Rat
regulation of synapse structure and activityGO:00508031280.903
Fly
actin filament bundle organizationGO:0061572280.896
Human
deathGO:00162652840.891
Human Yeast Rat
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.890
regulation of phosphate metabolic processGO:00192202100.888
Human Yeast
imaginal disc derived appendage morphogenesisGO:00351143950.879
vesicle mediated transportGO:00161923810.866
protein modification processGO:00362114380.858
Human Yeast Mouse Rat Worm
axon guidanceGO:00074112330.856
regulation of anatomical structure morphogenesisGO:00226032420.846
Rat
appendage developmentGO:00487364010.825
axis specificationGO:00097981670.818
regulation of cell developmentGO:00602842150.816
Rat
cellular protein modification processGO:00064644380.814
Human Yeast Mouse Rat Worm
axon extension involved in axon guidanceGO:0048846100.810
regulation of programmed cell deathGO:00430671520.810
Human Yeast Rat
phosphorylationGO:00163102940.801
Human Yeast Mouse Rat Worm
tube developmentGO:00352952440.798
Human
neuron projection extensionGO:1990138320.786
regulation of neuron differentiationGO:00456641030.786
Rat
regulation of multicellular organismal developmentGO:20000264140.784
Rat Fly
regulation of cell morphogenesis involved in differentiationGO:0010769610.777
Rat
gland developmentGO:00487321910.773
positive regulation of molecular functionGO:00440931360.744
Human Yeast
tissue morphogenesisGO:00487292970.741
Human
morphogenesis of an epitheliumGO:00020092760.741
Human
positive regulation of cell projection organizationGO:0031346290.736
Rat
appendage morphogenesisGO:00351073970.726
cell deathGO:00082192790.711
Human Yeast Rat
regulation of localizationGO:00328792750.691
Yeast
dendrite developmentGO:00163582040.688
Mouse Rat
regulation of synapse assemblyGO:0051963940.674
Fly
imaginal disc derived appendage developmentGO:00487373990.656
eye developmentGO:00016543230.654
positive regulation of cellular component organizationGO:00511301560.653
Human Rat Fly
regulation of cell projection organizationGO:0031344920.649
Rat
regulation of molecular functionGO:00650092170.622
Human Yeast
organelle localizationGO:00516401480.607
regulation of cell differentiationGO:00455953020.602
Rat
developmental programmed cell deathGO:00106231380.594
regulation of cell morphogenesisGO:00226041630.593
Rat
positive regulation of macromolecule metabolic processGO:00106044050.590
Human Yeast Rat
non sensory hair organizationGO:0035316470.585
negative regulation of response to stimulusGO:00485852580.576
regulation of cell deathGO:00109411730.575
Human Yeast Rat
embryonic development via the syncytial blastodermGO:00017001480.561
embryonic morphogenesisGO:00485982060.552
Worm
catabolic processGO:00090564090.550
actin filament organizationGO:00070151260.545
Human Fly
regulation of cell shapeGO:00083601130.530
cell migrationGO:00164772380.525
Worm
neuron projection guidanceGO:00974852410.509
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.505
lipid localizationGO:0010876540.499
Yeast
small molecule metabolic processGO:00442813050.496
negative regulation of cell communicationGO:00106482230.478
growthGO:00400073590.475
Yeast
regulation of axon extensionGO:003051680.462
retinal ganglion cell axon guidanceGO:0031290120.459
developmental cell growthGO:0048588520.459
regulation of cytoskeleton organizationGO:0051493890.456
Human Rat
positive regulation of nervous system developmentGO:0051962690.454
Rat Fly
regulation of cellular component sizeGO:0032535980.447
Human
regulation of axon extension involved in axon guidanceGO:004884140.439
cell growthGO:00160491080.436
Yeast
imaginal disc derived wing morphogenesisGO:00074763370.430
regulation of endopeptidase activityGO:0052548360.425
Human
negative regulation of growthGO:0045926840.418
negative regulation of developmental processGO:00510932010.418
dorsal closureGO:0007391790.411
wing disc morphogenesisGO:00074723440.407
axon extensionGO:0048675320.405
wnt signaling pathwayGO:0016055980.403
negative regulation of cell differentiationGO:00455961430.403
positive regulation of multicellular organismal processGO:00512401430.401
Rat Fly
synapse assemblyGO:00074161430.400
Fly
developmental growthGO:00485892800.393
protein phosphorylationGO:00064681690.390
Human Yeast Mouse Rat Worm
negative regulation of signalingGO:00230572190.386
apoptotic processGO:00069151590.386
Human Yeast Rat
negative regulation of signal transductionGO:00099682060.381
regulation of axon guidanceGO:1902667100.379
endocytosisGO:00068973100.378
regulation of actin filament polymerizationGO:0030833250.377
Human
actin filament bundle assemblyGO:0051017260.376
Human
regulation of cell sizeGO:0008361630.376
regulation of actin filament lengthGO:0030832270.372
Human
actin filament based processGO:00300292200.369
Human Rat Fly
dendrite morphogenesisGO:00488131990.367
Rat
cell proliferationGO:00082832990.361
Human
localization of cellGO:00516742570.356
Worm
regulation of vesicle mediated transportGO:0060627590.354
negative regulation of developmental growthGO:0048640640.348
actin filament polymerizationGO:0030041270.348
Human
positive regulation of hydrolase activityGO:0051345780.345
enzyme linked receptor protein signaling pathwayGO:00071671790.343
regulation of synapse organizationGO:00508071100.341
Fly
regulation of endocytosisGO:0030100370.331
organic substance catabolic processGO:19015753080.329
regulation of growthGO:00400082330.318
positive regulation of response to stimulusGO:00485843230.316
Human Yeast
negative regulation of synapse assemblyGO:0051964390.316
regulation of phosphorylationGO:00423251470.315
Human Yeast
salivary gland morphogenesisGO:00074351450.309
nucleotide catabolic processGO:00091661090.307
ribonucleoside catabolic processGO:00424541120.298
asymmetric cell divisionGO:0008356370.295
stem cell proliferationGO:0072089880.292
larval developmentGO:00021641040.289
Worm
sensory organ morphogenesisGO:00905962600.288
regionalizationGO:00030024160.282
positive regulation of nucleobase containing compound metabolic processGO:00459353320.281
Rat
neuron projection extension involved in neuron projection guidanceGO:1902284100.279
eye morphogenesisGO:00485922600.275
regulation of neuron projection developmentGO:0010975690.274
Rat
cellular nitrogen compound catabolic processGO:00442701650.265
regulation of catalytic activityGO:00507901850.264
Human Yeast
positive regulation of signal transductionGO:00099672230.263
Human Yeast
maintenance of locationGO:0051235730.248
positive regulation of catalytic activityGO:00430851180.248
Human Yeast
positive regulation of axon guidanceGO:190266910.244
purine nucleoside triphosphate catabolic processGO:00091461080.242
guanosine containing compound metabolic processGO:1901068740.242
biological adhesionGO:00226101380.242
purine ribonucleoside triphosphate metabolic processGO:00092051190.242
positive regulation of phosphorus metabolic processGO:00105621390.241
Human Yeast
embryo development ending in birth or egg hatchingGO:00097921520.238
Worm
morphogenesis of embryonic epitheliumGO:0016331940.236
purine nucleotide catabolic processGO:00061951090.236
regulation of cell proliferation involved in imaginal disc derived wing morphogenesisGO:009025620.232
tube morphogenesisGO:00352391910.231
Human
programmed cell deathGO:00125012570.231
Human Yeast Rat
regulation of anatomical structure sizeGO:00900661630.228
Human
aromatic compound catabolic processGO:00194391660.225
mapk cascadeGO:00001651070.223
Human Yeast
heterocycle catabolic processGO:00467001660.220
establishment of organelle localizationGO:00516561220.220
regulation of hydrolase activityGO:0051336970.220
Human
regulation of developmental growthGO:00486381740.218
regulation of cell proliferationGO:00421271630.218
Human
regulation of apoptotic processGO:00429811300.216
Human Yeast Rat
intracellular signal transductionGO:00355563000.208
Human Yeast
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.207
Human
regulation of proteolysisGO:0030162870.202
Human
carbohydrate derivative catabolic processGO:19011361180.201
negative regulation of cellular component organizationGO:00511291080.201
regulation of intracellular signal transductionGO:19025312360.200
Human Yeast
regulation of cellular component movementGO:0051270420.197
imaginal disc derived wing hair organizationGO:0035317450.193
gland morphogenesisGO:00226121450.190
post embryonic appendage morphogenesisGO:00351203850.184
negative regulation of cell developmentGO:0010721620.184
purine ribonucleotide catabolic processGO:00091541090.182
positive regulation of developmental processGO:00510941430.182
Rat Fly
cellular protein complex assemblyGO:0043623710.173
Human
salivary gland developmentGO:00074311620.173
negative regulation of cell deathGO:0060548810.173
Human
synapse organizationGO:00508081960.171
Mouse Fly
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.171
mushroom body developmentGO:0016319700.170
cell fate specificationGO:0001708710.166
retina morphogenesis in camera type eyeGO:006004220.165
negative regulation of cellular metabolic processGO:00313243820.162
Human
positive regulation of axonogenesisGO:005077220.162
regulation of axonogenesisGO:0050770320.160
tissue deathGO:00162711020.159
regulation of protein modification processGO:00313991120.157
Human Yeast
epithelial cell migrationGO:00106311480.157
glycosyl compound catabolic processGO:19016581120.157
ribonucleotide catabolic processGO:00092611090.155
imaginal disc derived leg morphogenesisGO:0007480800.154
purine containing compound catabolic processGO:00725231120.153
positive regulation of axon extensionGO:004577320.152
ameboidal type cell migrationGO:00016671510.148
cell proliferation involved in imaginal disc derived wing morphogenesisGO:009025520.147
cellular catabolic processGO:00442483720.140
rho protein signal transductionGO:0007266140.139
apoptotic cell clearanceGO:0043277140.138
regulation of phosphorus metabolic processGO:00511742100.138
Human Yeast
cell maturationGO:00484691440.138
regulation of cysteine type endopeptidase activityGO:2000116270.137
Human
purine ribonucleoside catabolic processGO:00461301120.132
protein complex assemblyGO:00064612000.131
Human
defense response to other organismGO:00985422250.131
positive regulation of cell migrationGO:003033520.130
regulation of stress activated protein kinase signaling cascadeGO:0070302420.125
Human
guanosine containing compound catabolic processGO:1901069740.124
adherens junction organizationGO:0034332270.122
cell motilityGO:00488702510.120
Worm
unidimensional cell growthGO:0009826150.117
negative regulation of multicellular organismal processGO:00512411420.114
muscle structure developmentGO:00610612240.114
Fly
regulation of actin filament based processGO:0032970420.114
Human Rat
ribonucleoside triphosphate metabolic processGO:00091991190.114
oocyte developmentGO:00485991240.113
instar larval developmentGO:0002168550.112
protein polymerizationGO:0051258420.111
Human
developmental maturationGO:00217001720.111
cell cycle checkpointGO:0000075950.111
regulation of multi organism processGO:00439001310.109
purine nucleoside catabolic processGO:00061521120.109
positive regulation of catabolic processGO:00098961050.108
compound eye developmentGO:00487493070.108
regulation of cellular localizationGO:00603411360.106
Yeast
positive regulation of cell morphogenesis involved in differentiationGO:0010770120.106
Rat
organic cyclic compound catabolic processGO:19013611680.105
negative regulation of gene expressionGO:00106293870.104
Human Yeast
nucleoside triphosphate catabolic processGO:00091431080.103
ribonucleoside metabolic processGO:00091191270.103
organophosphate metabolic processGO:00196371950.101
phagocytosisGO:00069092150.100
negative regulation of nervous system developmentGO:0051961920.100
negative regulation of nitrogen compound metabolic processGO:00511722650.100
exocrine system developmentGO:00352721620.099
cell divisionGO:00513012480.099
Yeast
positive regulation of synapse assemblyGO:0051965290.098
Fly
nucleobase containing compound catabolic processGO:00346551650.095
regulation of protein polymerizationGO:0032271280.093
Human
positive regulation of peptidase activityGO:0010952290.093
cellular response to organic substanceGO:00713101320.092
Yeast Rat
organonitrogen compound catabolic processGO:19015651280.091
response to organic substanceGO:00100332840.091
Yeast Rat
oocyte axis specificationGO:00073091080.090
purine ribonucleoside metabolic processGO:00461281270.088
notch signaling pathwayGO:00072191200.088
single organism intracellular transportGO:19025822070.088
Yeast
cellular amine metabolic processGO:0044106120.087
response to external biotic stimulusGO:00432072930.084
organic substance transportGO:00717022570.082
Yeast
regulation of actin cytoskeleton organizationGO:0032956420.081
Human Rat
negative regulation of cellular protein metabolic processGO:0032269850.081
Human
ovarian follicle cell developmentGO:00307072480.080
positive regulation of jun kinase activityGO:004350740.080
Human
secretion by cellGO:00329401010.079
immune system processGO:00023763470.079
negative regulation of programmed cell deathGO:0043069720.079
Human
oocyte constructionGO:00073081120.078
regulation of purine nucleotide catabolic processGO:0033121480.078
positive regulation of biosynthetic processGO:00098913160.077
Rat
muscle organ developmentGO:00075171270.076
response to growth factorGO:0070848310.075
gastrulationGO:0007369700.074
organonitrogen compound metabolic processGO:19015643180.074
epithelial cell developmentGO:00020642740.074
leg disc developmentGO:0035218920.073
purine ribonucleoside triphosphate catabolic processGO:00092071080.073
regulation of protein metabolic processGO:00512462560.073
Human Yeast
regulation of cell cycle processGO:00105641810.072
Yeast
fatty acid metabolic processGO:0006631200.072
response to other organismGO:00517072930.072
muscle cell differentiationGO:00426921030.070
Fly
central nervous system developmentGO:00074172010.070
initiation of dorsal closureGO:0007392120.069
protein complex biogenesisGO:00702712010.069
Human
secretionGO:00469031090.069
regulation of locomotionGO:0040012420.068
regulation of peptidase activityGO:0052547390.068
Human
oxidation reduction processGO:00551141230.066
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.066
response to extracellular stimulusGO:00099911160.066
positive regulation of filopodium assemblyGO:0051491150.066
positive regulation of endopeptidase activityGO:0010950260.065
regulation of dendrite morphogenesisGO:0048814280.064
Rat
macromolecular complex assemblyGO:00650032560.063
Human Yeast
cellular response to growth factor stimulusGO:0071363300.063
regulation of stress activated mapk cascadeGO:0032872410.063
Human
negative regulation of apoptotic processGO:0043066630.062
Human
establishment of imaginal disc derived wing hair orientationGO:0001737240.061
positive regulation of immune system processGO:0002684680.061
salivary gland histolysisGO:0035070880.060
peripheral nervous system developmentGO:0007422520.059
camera type eye morphogenesisGO:004859320.058
dorsal ventral axon guidanceGO:003356320.058
regulation of protein modification by small protein conjugation or removalGO:1903320250.058
collateral sproutingGO:004866830.058
cholesterol homeostasisGO:004263230.058
regulation of cell motilityGO:2000145230.057
anterior posterior axis specificationGO:00099481090.057
positive regulation of cellular biosynthetic processGO:00313283160.057
Rat
regulation of cellular catabolic processGO:00313291570.057
response to biotic stimulusGO:00096072940.056
oocyte differentiationGO:00099941450.056
epithelium migrationGO:00901321480.055
positive regulation of protein metabolic processGO:00512471280.053
Human Yeast
spindle organizationGO:00070512530.053
actin polymerization or depolymerizationGO:0008154310.052
Human
negative regulation of phosphorus metabolic processGO:0010563450.052
nucleobase containing small molecule metabolic processGO:00550861740.052
regulation of wnt signaling pathwayGO:0030111680.051
nucleoside catabolic processGO:00091641120.051
establishment of synaptic vesicle localizationGO:0097480500.051
retina development in camera type eyeGO:006004140.050
ribonucleotide metabolic processGO:00092591450.049
cellular macromolecular complex assemblyGO:00346221530.047
Human Yeast
positive regulation of cellular component biogenesisGO:0044089800.047
Human Fly
regulation of stress fiber assemblyGO:005149260.047
Human
branching morphogenesis of an epithelial tubeGO:0048754450.046
Human
dorsal ventral pattern formationGO:00099531330.046
negative regulation of molecular functionGO:0044092510.046
Human
protein ubiquitinationGO:0016567700.045
mesoderm developmentGO:0007498780.045
regulation of cellular response to stressGO:0080135890.045
Human
epithelial cell differentiationGO:00308553220.045
regulation of nucleotide metabolic processGO:0006140620.044
proteolysisGO:00065081920.044
Human
salivary gland cell autophagic cell deathGO:0035071830.044
digestive tract morphogenesisGO:00485461270.044
organophosphate catabolic processGO:00464341120.044
positive regulation of intracellular signal transductionGO:19025331160.043
Human Yeast
regulation of mapk cascadeGO:0043408920.043
Human Yeast
regulation of dendrite developmentGO:0050773370.042
Rat
glycosyl compound metabolic processGO:19016571270.041
positive regulation of cellular catabolic processGO:0031331950.040
purine nucleoside triphosphate metabolic processGO:00091441190.040
detection of stimulusGO:00516061560.040
actomyosin structure organizationGO:0031032560.039
Human
vesicle organizationGO:0016050440.039
nucleoside phosphate metabolic processGO:00067531620.039
neural precursor cell proliferationGO:0061351750.039
endosomal transportGO:0016197440.039
regulation of protein phosphorylationGO:0001932640.039
Human Yeast
regulation of extent of cell growthGO:006138780.039
nucleoside phosphate catabolic processGO:19012921100.038
negative regulation of nucleobase containing compound metabolic processGO:00459342610.038
positive regulation of lamellipodium organizationGO:190274570.037
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.037
dorsal closure elongation of leading edge cellsGO:0007394100.037
cellular response to chemical stimulusGO:00708871990.037
Yeast Rat
stem cell maintenanceGO:0019827670.037
positive regulation of nitrogen compound metabolic processGO:00511733540.037
Rat
membrane tubulationGO:009732040.037
oxoacid metabolic processGO:00434361030.037
regulation of cellular amine metabolic processGO:003323830.037
negative regulation of epithelial cell proliferationGO:005068040.036
regulation of mitotic cell cycleGO:00073461900.036
Yeast
camera type eye developmentGO:004301040.036
positive regulation of rna biosynthetic processGO:19026802660.035
regulation of immune system processGO:00026821760.035
ion transmembrane transportGO:00342201220.035
response to organic cyclic compoundGO:0014070890.035
positive regulation of establishment of protein localization to plasma membraneGO:009000430.035
positive regulation of cellular protein metabolic processGO:00322701180.035
Human Yeast
organelle assemblyGO:00709251980.035
Yeast
positive regulation of cell developmentGO:0010720610.034
Rat
regulation of actin polymerization or depolymerizationGO:0008064270.034
Human
signal releaseGO:0023061490.034
response to insulinGO:0032868290.034
Rat
anterior posterior axis specification embryoGO:00085951030.033
protein localizationGO:00081042840.033
Yeast Mouse
transcription from rna polymerase ii promoterGO:00063663680.033
regulation of cell cycleGO:00517262910.033
Yeast
regulation of neuron deathGO:1901214260.033
Rat
transmembrane transportGO:00550851390.033
Yeast
histolysisGO:00075591020.033
receptor clusteringGO:004311330.032
Mouse
defense response to virusGO:0051607230.032
motor neuron axon guidanceGO:0008045580.031
regulation of lamellipodium organizationGO:1902743150.031
organelle fissionGO:00482853400.031
Yeast
gtp catabolic processGO:0006184720.030
response to unfolded proteinGO:000698690.030
positive regulation of actin filament polymerizationGO:0030838110.030
positive regulation of phosphorylationGO:0042327870.030
Human Yeast
regulation of cellular protein metabolic processGO:00322682430.030
Human Yeast
organic acid metabolic processGO:00060821030.030
cell cell junction organizationGO:0045216550.030
positive regulation of proteolysisGO:0045862520.030
regulation of lipid transportGO:003236830.029
compound eye morphogenesisGO:00017452490.029
non canonical wnt signaling pathwayGO:003556780.029
regulation of ras protein signal transductionGO:0046578930.029
positive regulation of signalingGO:00230562430.029
Human Yeast
immune response regulating signaling pathwayGO:000276420.028
regulation of organ morphogenesisGO:2000027780.028
single organism catabolic processGO:00447122280.028
adult locomotory behaviorGO:0008344760.028
chromatin organizationGO:00063252070.028
Yeast
actin cytoskeleton reorganizationGO:0031532220.028
Human
leg disc morphogenesisGO:0007478800.028
sensory perception of touchGO:0050975110.028
syncytium formationGO:0006949430.028
Fly
cell recognitionGO:00080371020.027
monovalent inorganic cation transportGO:0015672400.027
autophagic cell deathGO:0048102830.027
response to transforming growth factor betaGO:0071559180.027
regulation of organelle organizationGO:00330431960.027
Human Yeast Rat
regulation of jnk cascadeGO:0046328400.026
Human
cholesterol transportGO:003030120.026
positive regulation of gtp catabolic processGO:0033126430.026
neural retina developmentGO:000340740.025
endoderm formationGO:000170630.025
generation of precursor metabolites and energyGO:0006091420.025
heart morphogenesisGO:0003007320.025
regulation of transferase activityGO:0051338580.025
Human Yeast
regulation of cell migrationGO:0030334220.025
purine nucleotide metabolic processGO:00061631460.025
purine ribonucleotide metabolic processGO:00091501450.025
positive regulation of phosphate metabolic processGO:00459371390.024
Human Yeast
homeostatic processGO:00425921990.024
transforming growth factor beta receptor signaling pathwayGO:0007179160.024
eye photoreceptor cell differentiationGO:00017541450.024
positive regulation of cell deathGO:0010942690.024
Human Yeast Rat
axon midline choice point recognitionGO:0016199260.024
bmp signaling pathway involved in malpighian tubule cell chemotaxisGO:006135330.023
positive regulation of phagocytosis engulfmentGO:006010010.023
syncytium formation by plasma membrane fusionGO:0000768430.023
Fly
positive regulation of purine nucleotide metabolic processGO:1900544550.023
positive regulation of neurogenesisGO:0050769410.023
Rat
negative regulation of transferase activityGO:0051348180.023
regulation of transcription from rna polymerase ii promoterGO:00063573780.023
negative regulation of protein metabolic processGO:0051248850.023
Human
regulation of canonical wnt signaling pathwayGO:0060828150.023
mitotic spindle organizationGO:00070522200.023
filopodium assemblyGO:0046847330.023
positive regulation of gtpase activityGO:0043547430.023
stress fiber assemblyGO:004314960.022
Human
regulation of behaviorGO:0050795750.022
regulation of chemotaxisGO:0050920120.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.022
nucleoside triphosphate metabolic processGO:00091411200.022
positive regulation of transcription dna templatedGO:00458932660.022
negative regulation of cell cycle processGO:00109481090.022
intracellular transportGO:00469072280.022
Yeast
ras protein signal transductionGO:0007265880.022
endodermal cell fate commitmentGO:000171130.022
formation of organ boundaryGO:0010160300.021
meiotic cell cycle processGO:19030461320.021
pseudocleavage involved in syncytial blastoderm formationGO:003058990.021
cellular response to unfolded proteinGO:003462090.021
negative regulation of rna biosynthetic processGO:19026792400.021
positive regulation of neuron projection developmentGO:0010976140.021
Rat
negative regulation of cellular biosynthetic processGO:00313272770.021
nucleocytoplasmic transportGO:0006913720.021
Yeast
brain developmentGO:00074201200.021
regulation of filopodium assemblyGO:0051489240.021
positive regulation of protein modification processGO:0031401580.021
Human Yeast
neuron maturationGO:0042551310.021
nucleoside metabolic processGO:00091161270.021
cortical actin cytoskeleton organizationGO:0030866240.021
jnk cascadeGO:0007254500.021
Human
establishment of spindle localizationGO:0051293220.021
regulation of notch signaling pathwayGO:00085931000.020
positive regulation of cell motilityGO:200014730.020
negative regulation of nucleic acid templated transcriptionGO:19035072400.020
cellular response to endogenous stimulusGO:0071495800.020
Rat
morphogenesis of larval imaginal disc epitheliumGO:001633550.020
regulation of stem cell proliferationGO:0072091400.020
forebrain developmentGO:003090020.020
regulation of hemocyte proliferationGO:0035206370.020
stress activated protein kinase signaling cascadeGO:0031098550.019
Human
cell competition in a multicellular organismGO:0035212100.019
positive regulation of protein polymerizationGO:0032273140.019
purine containing compound metabolic processGO:00725211550.019
response to bacteriumGO:00096171980.019
regulation of small gtpase mediated signal transductionGO:0051056930.019
meiotic cell cycleGO:00513211710.019
ribonucleoside triphosphate catabolic processGO:00092031080.018
positive regulation of purine nucleotide catabolic processGO:0033123460.018
monocarboxylic acid transportGO:001571830.018
negative regulation of mitotic cell cycle phase transitionGO:19019911030.018
cellular macromolecule localizationGO:00707272200.017
Yeast Mouse
extracellular structure organizationGO:0043062460.017
negative regulation of notch signaling pathwayGO:0045746410.017
cellular response to topologically incorrect proteinGO:0035967100.017
regulation of protein localizationGO:0032880760.017
Yeast
dna integrity checkpointGO:0031570810.017
response to abiotic stimulusGO:00096283410.017
Yeast Rat
pupal developmentGO:0035209110.017
hair cell differentiationGO:0035315470.017
negative regulation of neurogenesisGO:0050768530.017
endodermal cell differentiationGO:003598730.016
glutamate secretionGO:001404710.016
negative regulation of cellular response to growth factor stimulusGO:009028860.016
maintenance of location in cellGO:0051651280.016
autophagyGO:00069141080.016
cellular respirationGO:0045333260.016
response to topologically incorrect proteinGO:0035966100.016
axon choice point recognitionGO:0016198260.016
regulation of kinase activityGO:0043549530.016
Human Yeast
positive regulation of immune responseGO:0050778630.016
gtp metabolic processGO:0046039720.016
cytoplasmic microtubule organizationGO:0031122220.015
posttranscriptional gene silencing by rnaGO:0035194450.015
positive regulation of autophagyGO:0010508210.015
ethanolamine containing compound metabolic processGO:004243940.015

Pak disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
disease of cellular proliferationDOID:1456600.022
cardiovascular system diseaseDOID:128700.016