IMP: Integrative Multi-species Prediction

Drosophila melanogaster

65 known processes

Rdl (Dmel_CG10537)

Resistant to dieldrin

(Aliases: CG10537,Rd1,GABAr,GABA[[A]] receptor,DmRDL,LCCH1,DmRdl,GABA[[A]],Dmel\CG10537,rdl,RDL,gaba,GABA)

Entrez: 39054
FLYBASE: FBgn0004244
UniProtKB: P25123
UniProtKB: M9PHV2
UniProtKB: M9PEV8
UniProtKB: M9PBZ1

Process Predictions
Disease Predictions

Rdl biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
rhythmic behavior	GO:0007622	76	0.933
adult behavior	GO:0030534	137	0.918	Fly
cation transmembrane transport	GO:0098655	88	0.862
locomotory behavior	GO:0007626	176	0.857
single organism behavior	GO:0044708	391	0.759
response to ethanol	GO:0045471	59	0.715
ion transmembrane transport	GO:0034220	122	0.625	Fly
metal ion transport	GO:0030001	74	0.616
sleep	GO:0030431	49	0.587
circadian behavior	GO:0048512	76	0.568
response to abiotic stimulus	GO:0009628	341	0.553
transmembrane transport	GO:0055085	139	0.507	Fly
regulation of behavior	GO:0050795	75	0.488
learning or memory	GO:0007611	141	0.483
circadian rhythm	GO:0007623	105	0.456
rhythmic process	GO:0048511	106	0.446
taxis	GO:0042330	304	0.393	Fly
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.390
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.378
feeding behavior	GO:0007631	50	0.376
response to alkaloid	GO:0043279	26	0.368
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.350
neuropeptide signaling pathway	GO:0007218	45	0.341
multi organism behavior	GO:0051705	175	0.331
small molecule metabolic process	GO:0044281	305	0.330
positive regulation of biosynthetic process	GO:0009891	316	0.322
regulation of synaptic transmission	GO:0050804	69	0.312
g protein coupled receptor signaling pathway	GO:0007186	136	0.304
regulation of circadian rhythm	GO:0042752	49	0.294
behavioral response to ethanol	GO:0048149	49	0.285
learning	GO:0007612	75	0.264
ion transport	GO:0006811	145	0.259
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.246
response to oxygen containing compound	GO:1901700	200	0.241	Fly
response to mechanical stimulus	GO:0009612	28	0.232
multi multicellular organism process	GO:0044706	123	0.226
associative learning	GO:0008306	65	0.216
response to temperature stimulus	GO:0009266	106	0.213	Fly
organonitrogen compound biosynthetic process	GO:1901566	117	0.185
transcription from rna polymerase ii promoter	GO:0006366	368	0.182
response to anesthetic	GO:0072347	9	0.181
carbohydrate derivative biosynthetic process	GO:1901137	85	0.179
response to radiation	GO:0009314	155	0.176
male courtship behavior veined wing generated song production	GO:0045433	20	0.170
regulation of multicellular organismal development	GO:2000026	414	0.165
inorganic cation transmembrane transport	GO:0098662	61	0.162
neurological system process	GO:0050877	358	0.158
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.154
regulation of molecular function	GO:0065009	217	0.153
heart process	GO:0003015	37	0.152
regulation of ion transport	GO:0043269	39	0.151
regulation of circadian sleep wake cycle	GO:0042749	25	0.150
synaptic target recognition	GO:0008039	45	0.149
nucleobase containing small molecule metabolic process	GO:0055086	174	0.149
positive regulation of rna metabolic process	GO:0051254	271	0.147
molting cycle chitin based cuticle	GO:0007591	56	0.145
regulation of localization	GO:0032879	275	0.144
cation transport	GO:0006812	110	0.143
response to organic substance	GO:0010033	284	0.142	Fly
localization of cell	GO:0051674	257	0.141
positive regulation of cellular biosynthetic process	GO:0031328	316	0.128
response to inorganic substance	GO:0010035	44	0.126
regulation of membrane potential	GO:0042391	35	0.121
social behavior	GO:0035176	4	0.120
thermotaxis	GO:0043052	16	0.117	Fly
larval behavior	GO:0030537	42	0.116
neuron recognition	GO:0008038	101	0.113
response to oxidative stress	GO:0006979	86	0.108
response to insecticide	GO:0017085	14	0.105
purine containing compound metabolic process	GO:0072521	155	0.105
response to drug	GO:0042493	17	0.103
axonogenesis	GO:0007409	290	0.102
regulation of nervous system development	GO:0051960	248	0.101
chemotaxis	GO:0006935	249	0.100
mating	GO:0007618	120	0.098
positive regulation of molecular function	GO:0044093	136	0.095
regulation of ion transmembrane transport	GO:0034765	27	0.094
multicellular organismal reproductive behavior	GO:0033057	110	0.094
positive regulation of transcription dna templated	GO:0045893	266	0.093
regulation of system process	GO:0044057	36	0.092
multi organism reproductive behavior	GO:0044705	121	0.091
synaptic transmission	GO:0007268	288	0.091
regulation of cyclic nucleotide metabolic process	GO:0030799	13	0.091
cellular response to hormone stimulus	GO:0032870	44	0.091
axon guidance	GO:0007411	233	0.087
response to alcohol	GO:0097305	95	0.086
olfactory learning	GO:0008355	56	0.085
response to nitrogen compound	GO:1901698	90	0.085
negative regulation of homeostatic process	GO:0032845	2	0.083
cognition	GO:0050890	141	0.080
muscle tissue morphogenesis	GO:0060415	2	0.078
response to light stimulus	GO:0009416	124	0.078
regulation of catalytic activity	GO:0050790	185	0.078
carbohydrate derivative metabolic process	GO:1901135	217	0.077
choline catabolic process	GO:0042426	1	0.075
intraspecies interaction between organisms	GO:0051703	4	0.075
mating behavior	GO:0007617	106	0.074
organonitrogen compound metabolic process	GO:1901564	318	0.074
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.074
reproductive behavior	GO:0019098	122	0.073
regulation of epithelial cell proliferation	GO:0050678	4	0.072
regulation of olfactory learning	GO:0090328	8	0.071
acetylcholine metabolic process	GO:0008291	2	0.071
acetate ester metabolic process	GO:1900619	2	0.071
locomotor rhythm	GO:0045475	56	0.070
cellular cation homeostasis	GO:0030003	38	0.070
cellular response to endogenous stimulus	GO:0071495	80	0.070
developmental growth	GO:0048589	280	0.070
stem cell differentiation	GO:0048863	117	0.066
response to toxic substance	GO:0009636	22	0.065	Fly
negative regulation of molecular function	GO:0044092	51	0.062
positive regulation of response to stimulus	GO:0048584	323	0.062
memory	GO:0007613	94	0.061
catechol containing compound biosynthetic process	GO:0009713	3	0.061
detection of chemical stimulus	GO:0009593	93	0.061
regulation of transport	GO:0051049	181	0.057
regulation of transcription regulatory region dna binding	GO:2000677	3	0.055
courtship behavior	GO:0007619	68	0.055
purine ribonucleotide metabolic process	GO:0009150	145	0.053
regulation of anatomical structure size	GO:0090066	163	0.053
cellular amino acid metabolic process	GO:0006520	61	0.053
regulation of cell differentiation	GO:0045595	302	0.052
neuron projection guidance	GO:0097485	241	0.052
cyclic nucleotide metabolic process	GO:0009187	28	0.052
cellular homeostasis	GO:0019725	80	0.051
nucleoside phosphate biosynthetic process	GO:1901293	34	0.051
vesicle mediated transport	GO:0016192	381	0.051	Fly
single organism biosynthetic process	GO:0044711	206	0.050
regulation of locomotion	GO:0040012	42	0.050
positive regulation of signaling	GO:0023056	243	0.049
synaptic transmission cholinergic	GO:0007271	9	0.048
negative regulation of cell death	GO:0060548	81	0.047
positive regulation of macromolecule metabolic process	GO:0010604	405	0.047
immune response regulating signaling pathway	GO:0002764	2	0.047
oxoacid metabolic process	GO:0043436	103	0.047
actin filament based process	GO:0030029	220	0.046
negative regulation of response to stimulus	GO:0048585	258	0.046
potassium ion transport	GO:0006813	20	0.046
sensory organ morphogenesis	GO:0090596	260	0.045
cell motility	GO:0048870	251	0.045
regulation of cell death	GO:0010941	173	0.045
positive regulation of rna biosynthetic process	GO:1902680	266	0.045
regulation of camp metabolic process	GO:0030814	12	0.045
regulation of muscle contraction	GO:0006937	5	0.043
regulation of programmed cell death	GO:0043067	152	0.043
regulation of transmembrane transport	GO:0034762	27	0.043
circadian sleep wake cycle	GO:0042745	28	0.042
cyclic nucleotide biosynthetic process	GO:0009190	25	0.042
regulation of neurogenesis	GO:0050767	158	0.042
death	GO:0016265	284	0.042
catecholamine biosynthetic process	GO:0042423	3	0.042
forebrain development	GO:0030900	2	0.041
purine nucleotide metabolic process	GO:0006163	146	0.041
regulation of organelle organization	GO:0033043	196	0.041
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	17	0.041
wound healing	GO:0042060	75	0.041
cell death	GO:0008219	279	0.040
regulation of phosphorus metabolic process	GO:0051174	210	0.040
cellular metal ion homeostasis	GO:0006875	31	0.040
immune response activating signal transduction	GO:0002757	2	0.040
positive regulation of cell migration	GO:0030335	2	0.039
axon development	GO:0061564	297	0.039
motor neuron axon guidance	GO:0008045	58	0.038
cellular amide metabolic process	GO:0043603	80	0.038
eye photoreceptor cell differentiation	GO:0001754	145	0.038
heart development	GO:0007507	82	0.038
regulation of nucleotide metabolic process	GO:0006140	62	0.038
circulatory system development	GO:0072359	82	0.037
neuron death	GO:0070997	27	0.037
ribose phosphate metabolic process	GO:0019693	145	0.037
organic substance transport	GO:0071702	257	0.037
response to lipopolysaccharide	GO:0032496	4	0.037
cation homeostasis	GO:0055080	51	0.037
regulation of cell development	GO:0060284	215	0.037
response to organonitrogen compound	GO:0010243	75	0.037
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.037
response to decreased oxygen levels	GO:0036293	58	0.036
negative regulation of programmed cell death	GO:0043069	72	0.036
regulation of circadian sleep wake cycle sleep	GO:0045187	21	0.036
cell type specific apoptotic process	GO:0097285	38	0.036
cell maturation	GO:0048469	144	0.036
lateral inhibition	GO:0046331	206	0.036
sensory perception of chemical stimulus	GO:0007606	116	0.036
embryonic heart tube development	GO:0035050	22	0.036
negative regulation of neural precursor cell proliferation	GO:2000178	27	0.035
spinal cord development	GO:0021510	1	0.035
synapse assembly	GO:0007416	143	0.035
negative regulation of sequestering of calcium ion	GO:0051283	2	0.035
camp biosynthetic process	GO:0006171	17	0.035
neurotransmitter metabolic process	GO:0042133	2	0.035
regulation of cellular component biogenesis	GO:0044087	201	0.034
cellular response to peptide	GO:1901653	28	0.034
stem cell development	GO:0048864	79	0.033
cellular response to nitrogen compound	GO:1901699	51	0.033
chromatin remodeling	GO:0006338	72	0.033
cellular response to insulin stimulus	GO:0032869	28	0.033
regulation of cellular component movement	GO:0051270	42	0.032
negative regulation of biosynthetic process	GO:0009890	277	0.031
activation of innate immune response	GO:0002218	4	0.031
heart morphogenesis	GO:0003007	32	0.031
positive regulation of phosphate metabolic process	GO:0045937	139	0.031
positive regulation of immune response	GO:0050778	63	0.031
circadian sleep wake cycle sleep	GO:0050802	23	0.031
organic substance catabolic process	GO:1901575	308	0.031
regulation of synapse assembly	GO:0051963	94	0.031
mesenchymal cell differentiation	GO:0048762	1	0.030
peptide metabolic process	GO:0006518	80	0.030
monovalent inorganic cation transport	GO:0015672	40	0.030
chromatin modification	GO:0016568	147	0.030
cellular response to organic substance	GO:0071310	132	0.030
neurotransmitter catabolic process	GO:0042135	1	0.030
cell migration	GO:0016477	238	0.030
regulation of actin filament based process	GO:0032970	42	0.029
regionalization	GO:0003002	416	0.029
organic acid metabolic process	GO:0006082	103	0.029
response to organophosphorus	GO:0046683	2	0.029
muscle system process	GO:0003012	21	0.029
male mating behavior	GO:0060179	70	0.029
intracellular signal transduction	GO:0035556	300	0.029
metal ion homeostasis	GO:0055065	44	0.028
regulation of neuron projection development	GO:0010975	69	0.028
olfactory behavior	GO:0042048	97	0.027
adult locomotory behavior	GO:0008344	76	0.027
muscle organ development	GO:0007517	127	0.027
regulation of sequestering of calcium ion	GO:0051282	3	0.027
regulation of purine nucleotide biosynthetic process	GO:1900371	14	0.027
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.027
regulation of response to biotic stimulus	GO:0002831	63	0.027
cardiovascular system development	GO:0072358	82	0.027
regulation of multi organism process	GO:0043900	131	0.026
macromolecular complex assembly	GO:0065003	256	0.026
protein complex biogenesis	GO:0070271	201	0.026
homeostatic process	GO:0042592	199	0.026
nucleoside phosphate metabolic process	GO:0006753	162	0.026
amine metabolic process	GO:0009308	12	0.026
catabolic process	GO:0009056	409	0.026
regulation of phosphate metabolic process	GO:0019220	210	0.026
cellular response to carbohydrate stimulus	GO:0071322	4	0.025
muscle contraction	GO:0006936	13	0.025
growth	GO:0040007	359	0.025
positive regulation of cell communication	GO:0010647	250	0.025
carboxylic acid metabolic process	GO:0019752	92	0.025
response to insulin	GO:0032868	29	0.025
positive regulation of cell proliferation	GO:0008284	47	0.025
negative regulation of cell communication	GO:0010648	223	0.025
developmental maturation	GO:0021700	172	0.025
cell recognition	GO:0008037	102	0.024
skin development	GO:0043588	65	0.024
connective tissue development	GO:0061448	3	0.024
camera type eye development	GO:0043010	4	0.024
regulation of protein metabolic process	GO:0051246	256	0.024
regulation of immune response	GO:0050776	118	0.024
protein import into nucleus	GO:0006606	51	0.024
cellular catabolic process	GO:0044248	372	0.024
regulation of cell projection organization	GO:0031344	92	0.024
actin cytoskeleton organization	GO:0030036	206	0.024
antimicrobial humoral response	GO:0019730	99	0.023
endocytosis	GO:0006897	310	0.023	Fly
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.023
regulation of nucleotide biosynthetic process	GO:0030808	14	0.023
response to endogenous stimulus	GO:0009719	119	0.023
regulation of anatomical structure morphogenesis	GO:0022603	242	0.023
cellular response to lipopolysaccharide	GO:0071222	3	0.023
peripheral nervous system development	GO:0007422	52	0.023
positive regulation of cellular component biogenesis	GO:0044089	80	0.022
regulation of cellular protein metabolic process	GO:0032268	243	0.022
positive regulation of immune system process	GO:0002684	68	0.022
negative regulation of signaling	GO:0023057	219	0.022
adult chitin containing cuticle pigmentation	GO:0048085	16	0.022
immune response	GO:0006955	246	0.022
phagocytosis	GO:0006909	215	0.022	Fly
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.022
positive regulation of cyclic nucleotide metabolic process	GO:0030801	9	0.022
mesenchymal cell development	GO:0014031	1	0.022
cellular response to peptide hormone stimulus	GO:0071375	28	0.022
divalent inorganic cation homeostasis	GO:0072507	29	0.022
positive regulation of lyase activity	GO:0051349	10	0.021
larval feeding behavior	GO:0030536	15	0.021
positive regulation of programmed cell death	GO:0043068	62	0.021
response to wounding	GO:0009611	94	0.021
tissue morphogenesis	GO:0048729	297	0.021
eye development	GO:0001654	323	0.021
action potential	GO:0001508	13	0.021
positive regulation of behavior	GO:0048520	19	0.021
glycosyl compound metabolic process	GO:1901657	127	0.021
protein complex assembly	GO:0006461	200	0.021
neurotransmitter receptor metabolic process	GO:0045213	3	0.021
cellular response to oxygen containing compound	GO:1901701	79	0.021
response to organic cyclic compound	GO:0014070	89	0.021
macromolecule catabolic process	GO:0009057	161	0.021
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway	GO:0010579	7	0.021
detection of stimulus involved in sensory perception	GO:0050906	92	0.020
cellular response to biotic stimulus	GO:0071216	4	0.020
pigmentation	GO:0043473	75	0.020
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.020
sensory perception	GO:0007600	196	0.020
regulation of cellular amine metabolic process	GO:0033238	3	0.020
response to external biotic stimulus	GO:0043207	293	0.020
chromatin organization	GO:0006325	207	0.020
regulation of excitatory postsynaptic membrane potential	GO:0060079	3	0.020
dendrite guidance	GO:0070983	21	0.020
intracellular transport	GO:0046907	228	0.019
heart contraction	GO:0060047	26	0.019
negative regulation of synaptic transmission	GO:0050805	12	0.019
cellular chemical homeostasis	GO:0055082	40	0.019
histone modification	GO:0016570	106	0.019
chromosome organization	GO:0051276	360	0.019
regulation of cellular catabolic process	GO:0031329	157	0.019
regulation of neuron death	GO:1901214	26	0.019
regulation of cell proliferation	GO:0042127	163	0.019
proteolysis	GO:0006508	192	0.019
regulation of blood circulation	GO:1903522	21	0.019
positive regulation of nervous system development	GO:0051962	69	0.019
calcium ion homeostasis	GO:0055074	23	0.019
regulation of neuron differentiation	GO:0045664	103	0.019
single organism catabolic process	GO:0044712	228	0.018
regulation of purine nucleotide metabolic process	GO:1900542	62	0.018
segmentation	GO:0035282	207	0.018
programmed cell death	GO:0012501	257	0.018
regulation of heart contraction	GO:0008016	21	0.018
response to oxygen levels	GO:0070482	59	0.018
neuromuscular junction development	GO:0007528	149	0.018
positive regulation of signal transduction	GO:0009967	223	0.018
muscle organ morphogenesis	GO:0048644	7	0.018
inositol lipid mediated signaling	GO:0048017	4	0.018
photoreceptor cell development	GO:0042461	96	0.018
positive regulation of hydrolase activity	GO:0051345	78	0.018
circulatory system process	GO:0003013	37	0.018
lipid metabolic process	GO:0006629	121	0.017
protein modification process	GO:0036211	438	0.017
positive regulation of cell motility	GO:2000147	3	0.017
regulation of cellular ketone metabolic process	GO:0010565	3	0.017
eye morphogenesis	GO:0048592	260	0.017
dorsal ventral axis specification	GO:0009950	66	0.017
serotonin receptor signaling pathway	GO:0007210	5	0.017
cellular response to organonitrogen compound	GO:0071417	36	0.017
cellular divalent inorganic cation homeostasis	GO:0072503	23	0.017
blood circulation	GO:0008015	26	0.017
male courtship behavior veined wing extension	GO:0048065	22	0.017
organophosphate biosynthetic process	GO:0090407	46	0.017
positive regulation of catalytic activity	GO:0043085	118	0.017
positive regulation of phosphorus metabolic process	GO:0010562	139	0.016
positive regulation of i kappab kinase nf kappab signaling	GO:0043123	1	0.016
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.016
positive regulation of cyclic nucleotide biosynthetic process	GO:0030804	9	0.016
compound eye development	GO:0048749	307	0.016
regulation of immune system process	GO:0002682	176	0.016
protein catabolic process	GO:0030163	101	0.016
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.016
nucleotide metabolic process	GO:0009117	161	0.016
regulation of lyase activity	GO:0051339	14	0.016
response to extracellular stimulus	GO:0009991	116	0.016
dorsal ventral pattern formation	GO:0009953	133	0.016
membrane depolarization	GO:0051899	4	0.016
ribonucleotide metabolic process	GO:0009259	145	0.016
cell growth	GO:0016049	108	0.016
cell junction organization	GO:0034330	57	0.016
cell proliferation	GO:0008283	299	0.016
muscle cell development	GO:0055001	50	0.016
dopamine biosynthetic process	GO:0042416	3	0.016
apoptotic process	GO:0006915	159	0.015
light adaption	GO:0036367	3	0.015
multicellular organismal signaling	GO:0035637	12	0.015
regulation of heart rate	GO:0002027	11	0.015
regulation of cuticle pigmentation	GO:0048079	16	0.015
anesthesia resistant memory	GO:0007615	6	0.015
actin filament based movement	GO:0030048	26	0.015
negative regulation of cellular metabolic process	GO:0031324	382	0.015
negative regulation of apoptotic process	GO:0043066	63	0.015
acetylcholine catabolic process	GO:0006581	1	0.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger	GO:0007187	17	0.014
response to heat	GO:0009408	63	0.014
muscle tissue development	GO:0060537	30	0.014
organonitrogen compound catabolic process	GO:1901565	128	0.014
divalent metal ion transport	GO:0070838	26	0.014
negative regulation of rna biosynthetic process	GO:1902679	240	0.014
i kappab phosphorylation	GO:0007252	3	0.014
response to hypoxia	GO:0001666	53	0.014
biological adhesion	GO:0022610	138	0.014
compound eye photoreceptor cell differentiation	GO:0001751	140	0.014
epithelial cell migration	GO:0010631	148	0.014
sensory perception of smell	GO:0007608	80	0.014
ribonucleotide biosynthetic process	GO:0009260	28	0.014
response to hexose	GO:0009746	3	0.014
ameboidal type cell migration	GO:0001667	151	0.014
negative regulation of epithelial cell proliferation	GO:0050680	4	0.014
macromolecule methylation	GO:0043414	45	0.014
humoral immune response	GO:0006959	117	0.014
regulation of camp biosynthetic process	GO:0030817	12	0.014
cellular amine metabolic process	GO:0044106	12	0.014
skeletal muscle organ development	GO:0060538	48	0.014
positive regulation of multicellular organismal process	GO:0051240	143	0.014
regulation of cyclase activity	GO:0031279	13	0.014
protein phosphorylation	GO:0006468	169	0.014
larval development	GO:0002164	104	0.014
ion homeostasis	GO:0050801	55	0.013
carbohydrate metabolic process	GO:0005975	82	0.013
phosphorylation	GO:0016310	294	0.013
regulation of metal ion transport	GO:0010959	15	0.013
carbohydrate derivative catabolic process	GO:1901136	118	0.013
response to acid chemical	GO:0001101	25	0.013
heterochromatin organization	GO:0070828	25	0.013
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	4	0.013
cuticle pigmentation	GO:0048067	22	0.013
cytokinesis	GO:0000910	90	0.013
cellular potassium ion transport	GO:0071804	18	0.013
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.013
circadian sleep wake cycle process	GO:0022410	24	0.013
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.013
negative regulation of transcription dna templated	GO:0045892	237	0.013
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.013
regulation of tube size	GO:0035150	46	0.013
positive regulation of cellular catabolic process	GO:0031331	95	0.013
axon target recognition	GO:0007412	16	0.013
pigment cell differentiation	GO:0050931	3	0.013
regulation of intracellular transport	GO:0032386	64	0.013
negative regulation of developmental process	GO:0051093	201	0.013
regulation of sequence specific dna binding transcription factor activity	GO:0051090	12	0.013
cellular response to molecule of bacterial origin	GO:0071219	3	0.013
regulation of protein modification process	GO:0031399	112	0.012
organ growth	GO:0035265	56	0.012
regulation of transmembrane transporter activity	GO:0022898	6	0.012
regulation of pole plasm oskar mrna localization	GO:0007317	27	0.012
myotube differentiation	GO:0014902	46	0.012
sequestering of calcium ion	GO:0051208	5	0.012
cellular protein modification process	GO:0006464	438	0.012
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.012
conditioned taste aversion	GO:0001661	3	0.012
positive regulation of cell differentiation	GO:0045597	64	0.012
regulation of apoptotic process	GO:0042981	130	0.012
male courtship behavior	GO:0008049	63	0.012
single organism carbohydrate metabolic process	GO:0044723	72	0.012
neuron fate commitment	GO:0048663	50	0.012
regulation of mitotic cell cycle	GO:0007346	190	0.012
nephron tubule development	GO:0072080	3	0.012
regulation of phosphorylation	GO:0042325	147	0.012
cytoskeleton dependent cytokinesis	GO:0061640	81	0.012
response to nutrient levels	GO:0031667	114	0.012
negative regulation of transcription regulatory region dna binding	GO:2000678	3	0.012
cell adhesion	GO:0007155	136	0.012
response to biotic stimulus	GO:0009607	294	0.012
sex differentiation	GO:0007548	81	0.012
nucleotide biosynthetic process	GO:0009165	34	0.012
cell junction assembly	GO:0034329	42	0.012
production of molecular mediator of immune response	GO:0002440	46	0.012
retina development in camera type eye	GO:0060041	4	0.012
embryonic organ development	GO:0048568	50	0.012
negative regulation of cell differentiation	GO:0045596	143	0.011
negative regulation of catalytic activity	GO:0043086	42	0.011
signal transduction by phosphorylation	GO:0023014	107	0.011
retinal cone cell differentiation	GO:0042670	2	0.011
epidermis development	GO:0008544	65	0.011
chemical homeostasis	GO:0048878	92	0.011
synaptic transmission gabaergic	GO:0051932	1	0.011
phenol containing compound biosynthetic process	GO:0046189	6	0.011
establishment of localization in cell	GO:0051649	402	0.011
positive regulation of cellular protein metabolic process	GO:0032270	118	0.011
regulation of chromosome organization	GO:0033044	64	0.011
thermosensory behavior	GO:0040040	19	0.011
entrainment of circadian clock	GO:0009649	16	0.011
synaptic growth at neuromuscular junction	GO:0051124	119	0.011
extrinsic apoptotic signaling pathway	GO:0097191	1	0.011
actin filament organization	GO:0007015	126	0.011
organophosphate metabolic process	GO:0019637	195	0.011
regulation of neuron apoptotic process	GO:0043523	16	0.011
purine ribonucleoside metabolic process	GO:0046128	127	0.011
response to peptide hormone	GO:0043434	29	0.011
kidney development	GO:0001822	3	0.011
positive regulation of cyclase activity	GO:0031281	9	0.011
germ cell migration	GO:0008354	43	0.011
immune effector process	GO:0002252	98	0.011
synapse organization	GO:0050808	196	0.011
regulation of transporter activity	GO:0032409	6	0.011
anatomical structure homeostasis	GO:0060249	97	0.011
purine containing compound catabolic process	GO:0072523	112	0.011
neuron apoptotic process	GO:0051402	17	0.011
negative regulation of cellular protein metabolic process	GO:0032269	85	0.011
positive regulation of gene expression	GO:0010628	290	0.011
tissue migration	GO:0090130	155	0.011
anion transmembrane transport	GO:0098656	26	0.010	Fly
regulation of epithelial cell differentiation	GO:0030856	4	0.010
response to hormone	GO:0009725	45	0.010
response to glucose	GO:0009749	2	0.010

Rdl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
cancer	DOID:162	0.054
disease of cellular proliferation	DOID:14566	0.054
organ system cancer	DOID:0050686	0.047
disease of anatomical entity	DOID:7	0.028
nervous system disease	DOID:863	0.027
glucose metabolism disease	DOID:4194	0.026
acquired metabolic disease	DOID:0060158	0.026
carbohydrate metabolism disease	DOID:0050013	0.026
disease of metabolism	DOID:0014667	0.026
cardiovascular system disease	DOID:1287	0.014
musculoskeletal system disease	DOID:17	0.011
muscular disease	DOID:0080000	0.011

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