Drosophila melanogaster

61 known processes

tral (Dmel_CG10686)

trailer hitch

(Aliases: Lsm15,CG10686,p70,p67,TRAL,LSm15,Scd6p,DmLSm15,BEST:GH08269,anon-WO02059370.24,anon-EST:Posey139,Tral,Dmel\CG10686,anon-WO0172774.89)

tral biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oocyte axis specificationGO:00073091080.996
oocyte constructionGO:00073081120.995
oocyte developmentGO:00485991240.994
oocyte differentiationGO:00099941450.985
anterior posterior axis specification embryoGO:00085951030.959
rna localizationGO:00064031150.952
embryonic pattern specificationGO:00098801740.945
oocyte anterior posterior axis specificationGO:0007314720.938
blastoderm segmentationGO:00073501590.932
embryonic axis specificationGO:00005781070.920
anterior posterior axis specificationGO:00099481090.910
tripartite regional subdivisionGO:00073511030.909
anterior posterior pattern specificationGO:00099521360.899
pole plasm oskar mrna localizationGO:0045451460.887
positive regulation of gene expressionGO:00106282900.853
positive regulation of nucleic acid templated transcriptionGO:19035082660.818
transcription from rna polymerase ii promoterGO:00063663680.809
positive regulation of nitrogen compound metabolic processGO:00511733540.808
regionalizationGO:00030024160.773
chorion containing eggshell formationGO:00073041050.739
germarium derived egg chamber formationGO:00072931010.722
segmentationGO:00352822070.711
positive regulation of macromolecule biosynthetic processGO:00105572830.702
positive regulation of biosynthetic processGO:00098913160.697
pole plasm rna localizationGO:0007316520.696
pole plasm mrna localizationGO:0019094490.609
macromolecule catabolic processGO:00090571610.601
protein complex assemblyGO:00064612000.595
positive regulation of rna biosynthetic processGO:19026802660.591
eggshell formationGO:00307031050.578
positive regulation of transcription dna templatedGO:00458932660.572
rna catabolic processGO:0006401370.569
positive regulation of nucleobase containing compound metabolic processGO:00459353320.547
pole plasm assemblyGO:0007315610.536
intracellular mrna localizationGO:0008298660.534
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.514
regulation of transcription from rna polymerase ii promoterGO:00063573780.492
cellular macromolecule catabolic processGO:00442651360.490
actin cytoskeleton organizationGO:00300362060.488
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288140.486
positive regulation of rna metabolic processGO:00512542710.482
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.482
developmental maturationGO:00217001720.479
positive regulation of cellular biosynthetic processGO:00313283160.439
mitotic dna integrity checkpointGO:0044774750.428
ribonucleoprotein complex biogenesisGO:0022613310.428
Human
deathGO:00162652840.417
Worm
axis specificationGO:00097981670.396
mrna metabolic processGO:00160711240.393
protein modification by small protein conjugation or removalGO:00706471060.390
translationGO:0006412690.387
nucleobase containing compound catabolic processGO:00346551650.385
cellular macromolecular complex assemblyGO:00346221530.379
Human
negative regulation of biosynthetic processGO:00098902770.374
macromolecular complex assemblyGO:00650032560.373
Human
oocyte microtubule cytoskeleton organizationGO:0016325350.369
cellular catabolic processGO:00442483720.330
positive regulation of mrna processingGO:005068540.313
nuclear pore organizationGO:000699910.303
negative regulation of multicellular organismal processGO:00512411420.302
nuclear transcribed mrna catabolic processGO:0000956240.301
negative regulation of gene expressionGO:00106293870.278
organic substance catabolic processGO:19015753080.273
positive regulation of mrna metabolic processGO:190331350.269
maternal determination of anterior posterior axis embryoGO:0008358740.267
regulation of mrna processingGO:0050684710.253
cytoplasm organizationGO:0007028640.253
cellular response to abiotic stimulusGO:0071214580.248
gene silencingGO:00164581380.245
intracellular transportGO:00469072280.226
embryo development ending in birth or egg hatchingGO:00097921520.223
Worm
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.213
establishment of localization in cellGO:00516494020.211
protein modification processGO:00362114380.211
negative regulation of translationGO:0017148280.205
dorsal appendage formationGO:0046843470.201
protein modification by small protein conjugationGO:0032446790.195
regulation of intracellular transportGO:0032386640.194
negative regulation of macromolecule biosynthetic processGO:00105582700.192
eggshell chorion assemblyGO:0007306660.186
regulation of meiosisGO:004002030.182
rna processingGO:00063961470.180
posttranscriptional regulation of gene expressionGO:00106081450.180
catabolic processGO:00090564090.179
negative regulation of cellular metabolic processGO:00313243820.177
regulation of translationGO:0006417560.176
ribonucleoprotein complex assemblyGO:0022618230.159
Human
regulation of synapse assemblyGO:0051963940.154
protein localization to nucleusGO:0034504550.152
heterocycle catabolic processGO:00467001660.152
positive regulation of macromolecule metabolic processGO:00106044050.152
regulation of transportGO:00510491810.150
ribonucleoprotein complex subunit organizationGO:0071826280.149
Human
organic cyclic compound catabolic processGO:19013611680.149
cell maturationGO:00484691440.146
gene silencing by rnaGO:0031047570.145
dorsal ventral axis specificationGO:0009950660.140
mitotic cell cycle checkpointGO:0007093880.140
cellular macromolecule localizationGO:00707272200.140
aromatic compound catabolic processGO:00194391660.137
negative regulation of cellular biosynthetic processGO:00313272770.137
mrna catabolic processGO:0006402330.137
regulation of mrna metabolic processGO:1903311720.132
posttranscriptional gene silencingGO:0016441460.130
organic substance transportGO:00717022570.122
regulation of cytoplasmic transportGO:1903649470.120
cellular component assembly involved in morphogenesisGO:00109271510.120
ncrna metabolic processGO:0034660430.115
epithelial cell developmentGO:00020642740.114
regulation of pole plasm oskar mrna localizationGO:0007317270.110
posttranscriptional gene silencing by rnaGO:0035194450.107
mrna processingGO:00063971040.106
cellular protein modification processGO:00064644380.105
dna damage checkpointGO:0000077780.104
cellular protein complex assemblyGO:0043623710.103
cellular nitrogen compound catabolic processGO:00442701650.103
regulation of response to stressGO:00801342000.096
response to other organismGO:00517072930.092
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018480.089
organelle assemblyGO:00709251980.088
Human
regulation of mrna splicing via spliceosomeGO:0048024640.086
protein ubiquitinationGO:0016567700.083
regulation of cellular localizationGO:00603411360.081
protein complex biogenesisGO:00702712010.081
cellular response to chemical stimulusGO:00708871990.081
negative regulation of nitrogen compound metabolic processGO:00511722650.080
centrosome duplicationGO:00512981210.078
single organism intracellular transportGO:19025822070.077
protein targeting to nucleusGO:0044744510.076
body morphogenesisGO:001017120.076
carboxylic acid metabolic processGO:0019752920.072
single organism nuclear importGO:1902593510.072
ovarian follicle cell developmentGO:00307072480.071
regulation of nucleocytoplasmic transportGO:0046822350.070
negative regulation of signal transduction by p53 class mediatorGO:190179710.067
regulation of localizationGO:00328792750.066
spindle elongationGO:0051231830.065
single organism cellular localizationGO:19025801800.065
modification dependent macromolecule catabolic processGO:0043632790.065
actin filament organizationGO:00070151260.065
regulation of gene expression epigeneticGO:00400291280.064
chromatin organizationGO:00063252070.064
taxisGO:00423303040.062
cell divisionGO:00513012480.062
Worm
response to biotic stimulusGO:00096072940.062
regulation of protein metabolic processGO:00512462560.061
muscle structure developmentGO:00610612240.060
regulation of multicellular organismal developmentGO:20000264140.058
positive regulation of protein import into nucleusGO:0042307210.057
actin filament based processGO:00300292200.056
multi organism behaviorGO:00517051750.056
oocyte dorsal ventral axis specificationGO:0007310340.056
nucleobase containing compound transportGO:0015931560.056
ncrna processingGO:0034470300.056
nls bearing protein import into nucleusGO:000660750.055
chromosome condensationGO:0030261410.050
tissue deathGO:00162711020.049
appendage morphogenesisGO:00351073970.048
regulation of cell cycleGO:00517262910.047
nuclear envelope organizationGO:000699870.047
centrosome organizationGO:00512971630.046
intracellular mrna localization involved in pattern specification processGO:0060810560.046
neurological system processGO:00508773580.044
positive regulation of nucleocytoplasmic transportGO:0046824240.044
response to organic substanceGO:00100332840.044
mitotic spindle organizationGO:00070522200.044
Worm
dorsal ventral pattern formationGO:00099531330.043
sex differentiationGO:0007548810.043
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decayGO:190015340.043
mitotic cell cycle phase transitionGO:00447721380.042
centrosome cycleGO:00070981370.042
g2 dna damage checkpointGO:0031572690.042
development of primary sexual characteristicsGO:0045137500.042
response to organonitrogen compoundGO:0010243750.041
rna transportGO:0050658460.041
negative regulation of developmental processGO:00510932010.040
regulation of phosphatase activityGO:001092130.040
modification dependent protein catabolic processGO:0019941780.039
establishment of rna localizationGO:0051236470.039
regulation of cell cycle phase transitionGO:19019871300.038
response to oxygen containing compoundGO:19017002000.037
rrna processingGO:000636430.037
protein importGO:0017038550.036
meiotic cell cycleGO:00513211710.036
response to external biotic stimulusGO:00432072930.035
regulation of mitotic cell cycleGO:00073461900.035
protein import into nucleusGO:0006606510.034
meiotic chromosome segregationGO:0045132590.034
striated muscle cell developmentGO:0055002500.034
microtubule organizing center organizationGO:00310231680.034
chaeta developmentGO:0022416970.034
regulation of multi organism processGO:00439001310.033
columnar cuboidal epithelial cell developmentGO:00020662490.033
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.033
epithelial cell differentiationGO:00308553220.032
programmed cell deathGO:00125012570.032
Worm
negative regulation of oskar mrna translationGO:000731950.032
maintenance of locationGO:0051235730.029
positive regulation of developmental processGO:00510941430.029
oxoacid metabolic processGO:00434361030.029
humoral immune responseGO:00069591170.028
protein localizationGO:00081042840.028
regulation of oocyte developmentGO:0060281270.028
negative regulation of cell cycle phase transitionGO:19019881030.028
negative regulation of protein metabolic processGO:0051248850.028
developmental programmed cell deathGO:00106231380.027
positive regulation of multicellular organismal processGO:00512401430.027
regulation of embryonic developmentGO:0045995680.027
reproductive system developmentGO:0061458740.027
mitotic spindle elongationGO:0000022810.027
regulation of cell shapeGO:00083601130.027
oocyte microtubule cytoskeleton polarizationGO:0008103220.026
negative regulation of transpositionGO:0010529120.026
carbohydrate derivative metabolic processGO:19011352170.026
cellular protein localizationGO:00346131600.025
nucleocytoplasmic transportGO:0006913720.025
neuron projection guidanceGO:00974852410.025
nuclear importGO:0051170510.025
covalent chromatin modificationGO:00165691060.025
regulation of cellular protein metabolic processGO:00322682430.024
cellular protein catabolic processGO:0044257830.024
dna metabolic processGO:00062592270.024
regulation of response to external stimulusGO:00321011150.024
learning or memoryGO:00076111410.024
histone lysine demethylationGO:007007660.024
negative regulation of signal transductionGO:00099682060.023
regulation of protein import into nucleusGO:0042306280.023
positive regulation of cell proliferationGO:0008284470.023
organic acid metabolic processGO:00060821030.023
negative regulation of transcription dna templatedGO:00458922370.022
single organism behaviorGO:00447083910.022
muscle system processGO:0003012210.022
wing disc morphogenesisGO:00074723440.022
regulation of meiotic cell cycleGO:005144590.022
columnar cuboidal epithelial cell differentiationGO:00020652560.022
cell deathGO:00082192790.021
Worm
intracellular signal transductionGO:00355563000.021
regulation of mitotic cell cycle phase transitionGO:19019901300.021
vesicle mediated transportGO:00161923810.021
regulation of actin filament based processGO:0032970420.021
negative regulation of cellular protein metabolic processGO:0032269850.021
cell cycle phase transitionGO:00447701400.020
regulation of transpositionGO:0010528130.020
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.020
lipid metabolic processGO:00066291210.020
imaginal disc derived wing morphogenesisGO:00074763370.020
regulation of rna splicingGO:0043484690.020
negative regulation of rna biosynthetic processGO:19026792400.020
alternative mrna splicing via spliceosomeGO:0000380600.020
tissue morphogenesisGO:00487292970.020
positive regulation of mitotic cell cycle phase transitionGO:1901992200.020
wound healingGO:0042060750.019
protein catabolic processGO:00301631010.019
regulation of cellular component biogenesisGO:00440872010.019
response to abiotic stimulusGO:00096283410.019
protein polyubiquitinationGO:0000209110.019
mitotic g2 dna damage checkpointGO:0007095690.018
positive regulation of signalingGO:00230562430.018
mitotic cell cycle embryonicGO:0045448380.018
phagocytosisGO:00069092150.018
dna conformation changeGO:00711031050.018
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.017
regulation of transcription factor import into nucleusGO:0042990220.017
organonitrogen compound metabolic processGO:19015643180.017
chromosome organizationGO:00512763600.017
genitalia developmentGO:0048806260.017
morphogenesis of an epitheliumGO:00020092760.016
nuclear transportGO:0051169720.016
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.016
imaginal disc derived appendage morphogenesisGO:00351143950.016
chromatin modificationGO:00165681470.016
oocyte localization involved in germarium derived egg chamber formationGO:0030720120.016
rna splicingGO:0008380830.016
regulation of alternative mrna splicing via spliceosomeGO:0000381600.016
regulation of establishment of protein localizationGO:0070201610.016
mitotic dna damage checkpointGO:0044773740.015
rna interferenceGO:0016246270.015
synapse assemblyGO:00074161430.015
protein targetingGO:0006605640.015
cytoplasmic mrna processing body assemblyGO:0033962100.015
Human
gonad developmentGO:0008406500.015
response to endogenous stimulusGO:00097191190.015
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.014
regulation of organelle organizationGO:00330431960.014
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.014
response to nitrogen compoundGO:1901698900.014
small gtpase mediated signal transductionGO:0007264880.014
nucleic acid transportGO:0050657460.014
positive regulation of protein metabolic processGO:00512471280.014
reproductive structure developmentGO:0048608740.014
antimicrobial humoral responseGO:0019730990.013
positive regulation of lipid metabolic processGO:004583440.013
proteolysis involved in cellular protein catabolic processGO:0051603830.013
germ line cyst formationGO:0048134440.013
dna packagingGO:0006323910.013
transposition rna mediatedGO:003219730.013
positive regulation of transportGO:0051050920.013
regulation of protein export from nucleusGO:004682530.012
proteolysisGO:00065081920.012
regulation of oskar mrna translationGO:004601180.012
multi organism reproductive behaviorGO:00447051210.012
morphogenesis of follicular epitheliumGO:0016333360.012
maintenance of protein location in cellGO:0032507260.012
regulation of protein complex assemblyGO:0043254420.012
stem cell developmentGO:0048864790.012
axon choice point recognitionGO:0016198260.012
germarium derived oocyte fate determinationGO:0007294260.012
negative regulation of cell cycle processGO:00109481090.012
establishment of protein localizationGO:00451841630.012
cellular response to radiationGO:0071478520.011
nuclear transcribed mrna poly a tail shorteningGO:0000289120.011
regulation of intracellular protein transportGO:0033157460.011
negative regulation of cell cycleGO:00457861160.011
germarium derived oocyte differentiationGO:0030706290.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.011
regulation of hemocyte proliferationGO:0035206370.011
histone h3 k9 modificationGO:0061647120.011
response to temperature stimulusGO:00092661060.011
long term memoryGO:0007616620.011
ubiquitin dependent protein catabolic processGO:0006511780.011
defense responseGO:00069523000.011
establishment of ommatidial planar polarityGO:0042067490.011
regulation of cell differentiationGO:00455953020.011
cellular response to light stimulusGO:0071482370.010
female germ line cyst formationGO:0048135420.010
head developmentGO:00603221350.010
positive regulation of cell cycleGO:0045787430.010
growthGO:00400073590.010
positive regulation of cellular component biogenesisGO:0044089800.010
peptide metabolic processGO:0006518800.010
muscle cell differentiationGO:00426921030.010
regulation of actin filament polymerizationGO:0030833250.010
meiotic nuclear divisionGO:00071261510.010
meiotic chromosome condensationGO:001003230.010
regulation of cellular response to stressGO:0080135890.010

tral disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
benign neoplasmDOID:006007200.026
disease of cellular proliferationDOID:1456600.026
muscular diseaseDOID:008000000.014
musculoskeletal system diseaseDOID:1700.014
myopathyDOID:42300.014
muscle tissue diseaseDOID:6600.014
disease of anatomical entityDOID:700.014