IMP: Integrative Multi-species Prediction

Drosophila melanogaster

48 known processes

Lim3 (Dmel_CG10699)

CG10699 gene product from transcript CG10699-RB

(Aliases: lim3,l(2)Bd,CG10699,l(2)37Bd,CG15174,Dmel\CG10699,Lim-3A)

Entrez: 35184
FLYBASE: FBgn0002023
UniProtKB: Q9VJ00
UniProtKB: Q9VJ02
UniProtKB: M9NCY1
UniProtKB: M9PD53

Process Predictions
Disease Predictions

Lim3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
appendage development	GO:0048736	401	0.938	Fly
motor neuron axon guidance	GO:0008045	58	0.881
appendage morphogenesis	GO:0035107	397	0.791	Fly
compound eye development	GO:0048749	307	0.696	Fly
post embryonic appendage morphogenesis	GO:0035120	385	0.627	Fly
wing disc morphogenesis	GO:0007472	344	0.605
eye development	GO:0001654	323	0.594	Fly
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.582	Fly
negative regulation of gene expression	GO:0010629	387	0.520	Fly
sensory organ morphogenesis	GO:0090596	260	0.519
eye morphogenesis	GO:0048592	260	0.515
positive regulation of biosynthetic process	GO:0009891	316	0.504	Mouse Fly
dendrite development	GO:0016358	204	0.496	Fly
imaginal disc derived appendage development	GO:0048737	399	0.457	Fly
axonogenesis	GO:0007409	290	0.448
transcription from rna polymerase ii promoter	GO:0006366	368	0.434	Mouse Fly
neuron projection guidance	GO:0097485	241	0.424
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.388	Mouse Fly
compound eye morphogenesis	GO:0001745	249	0.338
positive regulation of rna biosynthetic process	GO:1902680	266	0.322	Mouse Fly
somatic muscle development	GO:0007525	66	0.320	Fly
embryo development ending in birth or egg hatching	GO:0009792	152	0.309	Fly
positive regulation of transcription dna templated	GO:0045893	266	0.305	Mouse Fly
regulation of nervous system development	GO:0051960	248	0.279
heart development	GO:0007507	82	0.273	Fly
embryonic development via the syncytial blastoderm	GO:0001700	148	0.272	Fly
neuromuscular junction development	GO:0007528	149	0.270
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.269	Fly
dendrite guidance	GO:0070983	21	0.264	Fly
axon guidance	GO:0007411	233	0.256
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.256	Mouse Fly
learning	GO:0007612	75	0.235
negative regulation of cellular biosynthetic process	GO:0031327	277	0.230	Fly
imaginal disc derived wing morphogenesis	GO:0007476	337	0.229
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.225	Fly
taxis	GO:0042330	304	0.222
regulation of cell differentiation	GO:0045595	302	0.207
chaeta development	GO:0022416	97	0.204	Fly
positive regulation of cellular biosynthetic process	GO:0031328	316	0.198	Mouse Fly
regionalization	GO:0003002	416	0.197	Mouse Fly
negative regulation of cellular metabolic process	GO:0031324	382	0.196	Fly
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.194	Fly
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.192
exocrine system development	GO:0035272	162	0.191
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.178	Mouse Fly
circulatory system development	GO:0072359	82	0.175	Fly
synapse assembly	GO:0007416	143	0.171
retinal ganglion cell axon guidance	GO:0031290	12	0.167
chemotaxis	GO:0006935	249	0.162
cell recognition	GO:0008037	102	0.162
imaginal disc pattern formation	GO:0007447	91	0.160	Fly
negative regulation of transcription dna templated	GO:0045892	237	0.159	Fly
regulation of neurogenesis	GO:0050767	158	0.157
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.155	Mouse Fly
cardiovascular system development	GO:0072358	82	0.153	Fly
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.153	Mouse Fly
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.149	Fly
regulation of axon extension involved in axon guidance	GO:0048841	4	0.143
synaptic growth at neuromuscular junction	GO:0051124	119	0.140
synapse organization	GO:0050808	196	0.138
neuron recognition	GO:0008038	101	0.137
neurological system process	GO:0050877	358	0.132
regulation of cell cycle	GO:0051726	291	0.130
forebrain development	GO:0030900	2	0.129	Mouse
positive regulation of rna metabolic process	GO:0051254	271	0.129	Mouse Fly
malpighian tubule development	GO:0072002	64	0.120
cell projection assembly	GO:0030031	94	0.115
chorion containing eggshell formation	GO:0007304	105	0.109
axon development	GO:0061564	297	0.109
regulation of cell development	GO:0060284	215	0.109
tube development	GO:0035295	244	0.108
regulation of axonogenesis	GO:0050770	32	0.108
negative regulation of biosynthetic process	GO:0009890	277	0.107	Fly
kidney development	GO:0001822	3	0.104
salivary gland morphogenesis	GO:0007435	145	0.100
chaeta morphogenesis	GO:0008407	42	0.099	Fly
regulation of neuron differentiation	GO:0045664	103	0.098
organ growth	GO:0035265	56	0.095
organelle assembly	GO:0070925	198	0.095
endocytosis	GO:0006897	310	0.093
negative regulation of rna biosynthetic process	GO:1902679	240	0.091	Fly
regulation of synapse assembly	GO:0051963	94	0.090
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.086	Mouse Fly
cellular component assembly involved in morphogenesis	GO:0010927	151	0.086
cardioblast differentiation	GO:0010002	20	0.085
regulation of multicellular organismal development	GO:2000026	414	0.081
cardiocyte differentiation	GO:0035051	29	0.081
cellular response to dna damage stimulus	GO:0006974	223	0.080
epithelial cell differentiation	GO:0030855	322	0.078
urogenital system development	GO:0001655	72	0.077
compound eye photoreceptor cell differentiation	GO:0001751	140	0.075
columnar cuboidal epithelial cell development	GO:0002066	249	0.074
limb development	GO:0060173	1	0.074
cytoskeleton dependent intracellular transport	GO:0030705	44	0.073
neuron projection extension	GO:1990138	32	0.071
stem cell differentiation	GO:0048863	117	0.070
developmental growth involved in morphogenesis	GO:0060560	65	0.068
growth	GO:0040007	359	0.067
wing disc pattern formation	GO:0035222	66	0.067	Fly
retina development in camera type eye	GO:0060041	4	0.067
chemosensory behavior	GO:0007635	106	0.065
cognition	GO:0050890	141	0.065
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.065
intracellular signal transduction	GO:0035556	300	0.065
positive regulation of gene expression	GO:0010628	290	0.064	Mouse Fly
single organism behavior	GO:0044708	391	0.062	Worm
embryonic morphogenesis	GO:0048598	206	0.062	Fly
detection of stimulus	GO:0051606	156	0.061	Worm
synaptic target recognition	GO:0008039	45	0.061
eggshell formation	GO:0030703	105	0.061
axon midline choice point recognition	GO:0016199	26	0.060
gland morphogenesis	GO:0022612	145	0.060
vesicle mediated transport	GO:0016192	381	0.060
telencephalon development	GO:0021537	2	0.060
cilium assembly	GO:0042384	38	0.058
photoreceptor cell development	GO:0042461	96	0.057
microtubule based transport	GO:0010970	42	0.057
cell cell adhesion	GO:0098609	26	0.056
spinal cord development	GO:0021510	1	0.056	Mouse
regulation of growth	GO:0040008	233	0.056
cell fate specification	GO:0001708	71	0.055	Mouse Fly
head development	GO:0060322	135	0.055	Mouse
gastrulation	GO:0007369	70	0.055
epithelial cell development	GO:0002064	274	0.054
brain development	GO:0007420	120	0.054	Mouse
renal tubule development	GO:0061326	64	0.054
regulation of neuron projection development	GO:0010975	69	0.053
tissue morphogenesis	GO:0048729	297	0.053	Fly
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.053
axon extension	GO:0048675	32	0.053
negative regulation of nervous system development	GO:0051961	92	0.053
eye photoreceptor cell development	GO:0042462	81	0.052
heart field specification	GO:0003128	0	0.052
axonal defasciculation	GO:0007414	12	0.051
actin filament organization	GO:0007015	126	0.050
axon target recognition	GO:0007412	16	0.050
developmental growth	GO:0048589	280	0.050
regulation of developmental growth	GO:0048638	174	0.049
negative regulation of cell communication	GO:0010648	223	0.049
cellular response to organic substance	GO:0071310	132	0.049
gland development	GO:0048732	191	0.049	Mouse Fly
camera type eye development	GO:0043010	4	0.049
axon extension involved in axon guidance	GO:0048846	10	0.049
regulation of behavior	GO:0050795	75	0.049
small molecule metabolic process	GO:0044281	305	0.049
larval development	GO:0002164	104	0.049	Fly
compound eye photoreceptor development	GO:0042051	78	0.048
developmental cell growth	GO:0048588	52	0.048
positive regulation of nervous system development	GO:0051962	69	0.048
salivary gland development	GO:0007431	162	0.047
negative regulation of cell cycle	GO:0045786	116	0.047
central nervous system development	GO:0007417	201	0.046	Mouse
ovarian follicle cell development	GO:0030707	248	0.045
lateral inhibition	GO:0046331	206	0.045
histolysis	GO:0007559	102	0.045	Fly
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.044	Fly
cardiac cell fate commitment	GO:0060911	17	0.044
limb morphogenesis	GO:0035108	1	0.043
phosphorylation	GO:0016310	294	0.043
regulation of cell morphogenesis	GO:0022604	163	0.043
negative regulation of signaling	GO:0023057	219	0.043
photoreceptor cell axon guidance	GO:0072499	23	0.042
regulation of axon guidance	GO:1902667	10	0.042
positive regulation of developmental process	GO:0051094	143	0.042
bolwig s organ development	GO:0055034	8	0.042
formation of anatomical boundary	GO:0048859	37	0.041
immune system development	GO:0002520	57	0.041	Fly
regulation of synapse organization	GO:0050807	110	0.041
positive regulation of phosphate metabolic process	GO:0045937	139	0.041
formation of organ boundary	GO:0010160	30	0.041
positive regulation of axonogenesis	GO:0050772	2	0.041
muscle structure development	GO:0061061	224	0.041	Fly
tube morphogenesis	GO:0035239	191	0.040
detection of chemical stimulus involved in sensory perception	GO:0050907	75	0.039
positive regulation of macromolecule metabolic process	GO:0010604	405	0.038	Mouse Fly
eye photoreceptor cell differentiation	GO:0001754	145	0.038
positive regulation of cell development	GO:0010720	61	0.038
cilium organization	GO:0044782	41	0.038
regulation of cell fate specification	GO:0042659	27	0.038
nephron development	GO:0072006	3	0.037
cardioblast cell fate commitment	GO:0042684	14	0.037
renal system development	GO:0072001	72	0.037
male courtship behavior veined wing vibration	GO:0016545	21	0.036
regulation of dendrite morphogenesis	GO:0048814	28	0.036
positive regulation of cell communication	GO:0010647	250	0.036
cellular amide metabolic process	GO:0043603	80	0.036
mushroom body development	GO:0016319	70	0.035
myoblast fusion	GO:0007520	43	0.035
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.035
regulation of anatomical structure morphogenesis	GO:0022603	242	0.035
phagocytosis	GO:0006909	215	0.035
small gtpase mediated signal transduction	GO:0007264	88	0.035
detection of external stimulus	GO:0009581	66	0.035	Worm
organonitrogen compound metabolic process	GO:1901564	318	0.034
positive regulation of response to stimulus	GO:0048584	323	0.034
kidney epithelium development	GO:0072073	3	0.034
associative learning	GO:0008306	65	0.034
positive regulation of phosphorus metabolic process	GO:0010562	139	0.034
regulation of molecular function	GO:0065009	217	0.034	Fly
negative regulation of neurogenesis	GO:0050768	53	0.034
positive regulation of cell differentiation	GO:0045597	64	0.034
photoreceptor cell differentiation	GO:0046530	170	0.033
regulation of cell cycle process	GO:0010564	181	0.033
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.033
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.033
regulation of cellular component biogenesis	GO:0044087	201	0.033
wnt signaling pathway	GO:0016055	98	0.033
regulation of wnt signaling pathway	GO:0030111	68	0.033
anterior posterior pattern specification	GO:0009952	136	0.032	Fly
regulation of phosphorylation	GO:0042325	147	0.032
localization of cell	GO:0051674	257	0.032
stress activated protein kinase signaling cascade	GO:0031098	55	0.032
nucleoside phosphate metabolic process	GO:0006753	162	0.032
heart process	GO:0003015	37	0.032
negative regulation of developmental process	GO:0051093	201	0.031
internal protein amino acid acetylation	GO:0006475	38	0.031
negative regulation of signal transduction	GO:0009968	206	0.031
regulation of synapse structure and activity	GO:0050803	128	0.030
signal transduction by phosphorylation	GO:0023014	107	0.030
regulation of cell fate commitment	GO:0010453	29	0.030
regulation of intracellular signal transduction	GO:1902531	236	0.030
regulation of response to external stimulus	GO:0032101	115	0.029
microtubule based movement	GO:0007018	51	0.029
morphogenesis of an epithelium	GO:0002009	276	0.029	Fly
leg disc development	GO:0035218	92	0.029	Fly
segmentation	GO:0035282	207	0.029	Fly
imaginal disc derived leg morphogenesis	GO:0007480	80	0.029	Fly
anatomical structure homeostasis	GO:0060249	97	0.029	Fly
homeostatic process	GO:0042592	199	0.028	Fly
eye antennal disc morphogenesis	GO:0007455	34	0.028
cell growth	GO:0016049	108	0.028
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.027
negative regulation of cell cycle process	GO:0010948	109	0.027
regulation of cell proliferation	GO:0042127	163	0.027
regulation of cellular component movement	GO:0051270	42	0.027
respiratory system development	GO:0060541	213	0.027
dephosphorylation	GO:0016311	51	0.027
response to organic substance	GO:0010033	284	0.027
dendrite morphogenesis	GO:0048813	199	0.026	Fly
embryonic heart tube development	GO:0035050	22	0.026
response to oxygen containing compound	GO:1901700	200	0.026
lamellipodium organization	GO:0097581	21	0.026
antennal morphogenesis	GO:0048800	14	0.026
cell cycle checkpoint	GO:0000075	95	0.026
positive regulation of signal transduction	GO:0009967	223	0.026
multicellular organismal reproductive behavior	GO:0033057	110	0.025
jnk cascade	GO:0007254	50	0.025
outflow tract morphogenesis	GO:0003151	4	0.025
positive regulation of exocytosis	GO:0045921	4	0.025
positive regulation of cellular amine metabolic process	GO:0033240	0	0.025
striated muscle cell differentiation	GO:0051146	90	0.025
non sensory hair organization	GO:0035316	47	0.024
regulation of heart morphogenesis	GO:2000826	3	0.024
convergent extension	GO:0060026	2	0.024
sex differentiation	GO:0007548	81	0.024
muscle organ development	GO:0007517	127	0.024	Fly
rho protein signal transduction	GO:0007266	14	0.024
negative regulation of cell differentiation	GO:0045596	143	0.024
cell motility	GO:0048870	251	0.024
mesoderm formation	GO:0001707	21	0.024
negative regulation of cell development	GO:0010721	62	0.024
hindbrain development	GO:0030902	2	0.024
axon choice point recognition	GO:0016198	26	0.024
stress activated mapk cascade	GO:0051403	52	0.024
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	4	0.024	Fly
organonitrogen compound catabolic process	GO:1901565	128	0.024
organ formation	GO:0048645	39	0.023
germ cell migration	GO:0008354	43	0.023
peptidyl lysine modification	GO:0018205	57	0.023
actin cytoskeleton organization	GO:0030036	206	0.023
cell adhesion	GO:0007155	136	0.023
establishment of planar polarity	GO:0001736	87	0.023
hemopoiesis	GO:0030097	46	0.023
regulation of epithelial cell migration open tracheal system	GO:2000274	11	0.023
cilium morphogenesis	GO:0060271	39	0.023
protein heterooligomerization	GO:0051291	4	0.023
sensory perception	GO:0007600	196	0.023
torso signaling pathway	GO:0008293	21	0.023	Fly
regulation of cell projection organization	GO:0031344	92	0.023
spindle organization	GO:0007051	253	0.023
g protein coupled receptor signaling pathway	GO:0007186	136	0.023
larval somatic muscle development	GO:0007526	19	0.022	Fly
determination of digestive tract left right asymmetry	GO:0071907	6	0.022
anterior posterior pattern specification imaginal disc	GO:0007448	16	0.022
ribonucleotide metabolic process	GO:0009259	145	0.022
dorsal ventral pattern formation	GO:0009953	133	0.022	Mouse Fly
mating	GO:0007618	120	0.022
nephron tubule development	GO:0072080	3	0.022
morphogenesis of a polarized epithelium	GO:0001738	93	0.022
purine ribonucleotide metabolic process	GO:0009150	145	0.022
catabolic process	GO:0009056	409	0.022
negative regulation of multicellular organismal process	GO:0051241	142	0.022
protein polymerization	GO:0051258	42	0.022
mrna splicing via spliceosome	GO:0000398	73	0.022
cellular response to chemical stimulus	GO:0070887	199	0.022
mitotic spindle organization	GO:0007052	220	0.022
macromolecular complex assembly	GO:0065003	256	0.022
regulation of localization	GO:0032879	275	0.022
actin filament bundle organization	GO:0061572	28	0.022
regulation of mrna metabolic process	GO:1903311	72	0.022
regulation of organ formation	GO:0003156	3	0.021
tissue death	GO:0016271	102	0.021	Fly
morphogenesis of embryonic epithelium	GO:0016331	94	0.021	Fly
filopodium assembly	GO:0046847	33	0.021
eye antennal disc development	GO:0035214	60	0.021
positive regulation of cellular component biogenesis	GO:0044089	80	0.021
purine nucleoside catabolic process	GO:0006152	112	0.021
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.020	Fly
epidermis development	GO:0008544	65	0.020
regulation of phosphate metabolic process	GO:0019220	210	0.020
hematopoietic or lymphoid organ development	GO:0048534	57	0.020	Fly
convergent extension involved in gastrulation	GO:0060027	2	0.020
purine containing compound metabolic process	GO:0072521	155	0.020
mapk cascade	GO:0000165	107	0.020
male gamete generation	GO:0048232	201	0.020
regulation of protein metabolic process	GO:0051246	256	0.020
branching morphogenesis of an epithelial tube	GO:0048754	45	0.020
wing and notum subfield formation	GO:0035309	13	0.020	Fly
ribonucleotide catabolic process	GO:0009261	109	0.020
cellular protein modification process	GO:0006464	438	0.020
dna metabolic process	GO:0006259	227	0.019
mitotic cell cycle checkpoint	GO:0007093	88	0.019
peptide metabolic process	GO:0006518	80	0.019
positive regulation of phosphorylation	GO:0042327	87	0.019
positive regulation of synapse assembly	GO:0051965	29	0.019
developmental programmed cell death	GO:0010623	138	0.019
hair cell differentiation	GO:0035315	47	0.019
detection of stimulus involved in sensory perception	GO:0050906	92	0.019
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.019
cell fate commitment involved in pattern specification	GO:0060581	31	0.019	Mouse Fly
rhabdomere development	GO:0042052	38	0.019
protein phosphorylation	GO:0006468	169	0.019
purine nucleotide catabolic process	GO:0006195	109	0.019
body morphogenesis	GO:0010171	2	0.019
peripheral nervous system development	GO:0007422	52	0.019
defasciculation of motor neuron axon	GO:0007415	8	0.019
lamellipodium assembly	GO:0030032	21	0.019
detection of abiotic stimulus	GO:0009582	66	0.019	Worm
response to ecdysone	GO:0035075	34	0.019
protein modification process	GO:0036211	438	0.019
epithelial cell migration open tracheal system	GO:0007427	32	0.019
substrate dependent cell migration	GO:0006929	3	0.019
negative regulation of organelle organization	GO:0010639	56	0.019
negative regulation of rna metabolic process	GO:0051253	251	0.019	Fly
protein acylation	GO:0043543	42	0.018
regulation of mrna processing	GO:0050684	71	0.018
regulation of dendrite development	GO:0050773	37	0.018
actin filament based process	GO:0030029	220	0.018
intracellular transport	GO:0046907	228	0.018
mitotic g2 dna damage checkpoint	GO:0007095	69	0.018
regulation of cardioblast differentiation	GO:0051890	9	0.018
response to lipopolysaccharide	GO:0032496	4	0.018
regulation of cell size	GO:0008361	63	0.018
nucleotide metabolic process	GO:0009117	161	0.018
cell division	GO:0051301	248	0.018
actin polymerization or depolymerization	GO:0008154	31	0.018
histone acetylation	GO:0016573	38	0.018
single organism intracellular transport	GO:1902582	207	0.018
organelle localization	GO:0051640	148	0.018
lymph gland development	GO:0048542	28	0.018	Fly
negative regulation of response to stimulus	GO:0048585	258	0.018
male courtship behavior veined wing generated song production	GO:0045433	20	0.018
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.018
ribose phosphate metabolic process	GO:0019693	145	0.018
dendrite self avoidance	GO:0070593	8	0.018
circulatory system process	GO:0003013	37	0.018
detection of chemical stimulus involved in sensory perception of smell	GO:0050911	50	0.018
positive regulation of compound eye retinal cell programmed cell death	GO:0046672	9	0.018
regulation of antimicrobial humoral response	GO:0002759	50	0.017
chemical homeostasis	GO:0048878	92	0.017
dorsal ventral axon guidance	GO:0033563	2	0.017
ras protein signal transduction	GO:0007265	88	0.017
axis elongation	GO:0003401	3	0.017
negative regulation of gene expression epigenetic	GO:0045814	77	0.017
peptidyl lysine acetylation	GO:0018394	39	0.017
regulation of map kinase activity	GO:0043405	17	0.017
cell cell adhesion via plasma membrane adhesion molecules	GO:0098742	26	0.017
cranial nerve development	GO:0021545	1	0.017
negative chemotaxis	GO:0050919	15	0.017
regulation of membrane potential	GO:0042391	35	0.017
wing disc dorsal ventral pattern formation	GO:0048190	47	0.017	Fly
nephron epithelium development	GO:0072009	3	0.017
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.017
positive regulation of multicellular organismal process	GO:0051240	143	0.017
cell fate specification involved in pattern specification	GO:0060573	8	0.017	Mouse Fly
cation transmembrane transport	GO:0098655	88	0.017
rna splicing via transesterification reactions	GO:0000375	73	0.017
reproductive structure development	GO:0048608	74	0.017	Mouse
olfactory bulb axon guidance	GO:0071678	3	0.017
negative regulation of cell cycle phase transition	GO:1901988	103	0.017
digestive tract development	GO:0048565	149	0.017
development of primary sexual characteristics	GO:0045137	50	0.017
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	26	0.017
regulation of gene expression epigenetic	GO:0040029	128	0.017
negative regulation of wnt signaling pathway	GO:0030178	28	0.016
positive regulation of cell migration	GO:0030335	2	0.016
neural retina development	GO:0003407	4	0.016
learning or memory	GO:0007611	141	0.016
myoblast proliferation	GO:0051450	3	0.016
regulation of jnk cascade	GO:0046328	40	0.016
kidney morphogenesis	GO:0060993	3	0.016
multi multicellular organism process	GO:0044706	123	0.016
regulation of cellular ketone metabolic process	GO:0010565	3	0.016
glycosyl compound metabolic process	GO:1901657	127	0.016
regulation of steroid metabolic process	GO:0019218	2	0.016
protein complex assembly	GO:0006461	200	0.016
regulation of catalytic activity	GO:0050790	185	0.016
male courtship behavior	GO:0008049	63	0.016
hemocyte migration	GO:0035099	19	0.015
specification of organ identity	GO:0010092	3	0.015
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.015	Fly
cardioblast cell fate specification	GO:0042685	9	0.015
cardiac cell fate determination	GO:0060913	3	0.015
nucleoside catabolic process	GO:0009164	112	0.015
regulation of catabolic process	GO:0009894	170	0.015
water homeostasis	GO:0030104	3	0.015
cell death	GO:0008219	279	0.015	Mouse
cell migration	GO:0016477	238	0.015
response to alcohol	GO:0097305	95	0.015
regulation of mapk cascade	GO:0043408	92	0.015
positive regulation of wnt signaling pathway	GO:0030177	25	0.015
hematopoietic progenitor cell differentiation	GO:0002244	1	0.015
nephron tubule morphogenesis	GO:0072078	3	0.015
mitotic g2 m transition checkpoint	GO:0044818	70	0.015
g2 dna damage checkpoint	GO:0031572	69	0.015
exocytosis	GO:0006887	28	0.015
regulation of mrna splicing via spliceosome	GO:0048024	64	0.015
immune system process	GO:0002376	347	0.015	Fly
semaphorin plexin signaling pathway	GO:0071526	4	0.015
digestive system development	GO:0055123	149	0.015
regulation of cellular amine metabolic process	GO:0033238	3	0.015
membrane organization	GO:0061024	112	0.015
actomyosin structure organization	GO:0031032	56	0.015
aromatic compound catabolic process	GO:0019439	166	0.015
regulation of blood circulation	GO:1903522	21	0.015
purine nucleoside metabolic process	GO:0042278	127	0.014
adult behavior	GO:0030534	137	0.014
histone exchange	GO:0043486	21	0.014
regulation of rna splicing	GO:0043484	69	0.014
muscle tissue morphogenesis	GO:0060415	2	0.014
positive regulation of transport	GO:0051050	92	0.014
autophagy	GO:0006914	108	0.014
embryonic axis specification	GO:0000578	107	0.014	Fly
negative regulation of smoothened signaling pathway	GO:0045879	16	0.014
chromatin remodeling	GO:0006338	72	0.014
stem cell development	GO:0048864	79	0.014
regulation of canonical wnt signaling pathway	GO:0060828	15	0.014
establishment of localization in cell	GO:0051649	402	0.014
amnioserosa maintenance	GO:0046665	5	0.014	Fly
regulation of lamellipodium assembly	GO:0010591	15	0.014
determination of imaginal disc primordium	GO:0007445	11	0.014
hemocyte differentiation	GO:0042386	38	0.014
actin filament polymerization	GO:0030041	27	0.014
regulation of gene silencing	GO:0060968	63	0.014
negative regulation of cellular component organization	GO:0051129	108	0.014
regulation of locomotion	GO:0040012	42	0.014
neuron projection extension involved in neuron projection guidance	GO:1902284	10	0.014
r7 cell development	GO:0045467	14	0.014
mitotic dna integrity checkpoint	GO:0044774	75	0.014
skeletal muscle organ development	GO:0060538	48	0.014
posttranscriptional gene silencing by rna	GO:0035194	45	0.014
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.014
mitotic dna damage checkpoint	GO:0044773	74	0.014
blastoderm segmentation	GO:0007350	159	0.014	Fly
regulation of protein polymerization	GO:0032271	28	0.014
ameboidal type cell migration	GO:0001667	151	0.014
purine ribonucleoside metabolic process	GO:0046128	127	0.014
regulation of cellular localization	GO:0060341	136	0.014
glandular epithelial cell differentiation	GO:0002067	1	0.014
peptidyl amino acid modification	GO:0018193	105	0.014
ribonucleoside catabolic process	GO:0042454	112	0.014
neuroblast differentiation	GO:0014016	29	0.014
gonad morphogenesis	GO:0035262	7	0.014
glycosyl compound catabolic process	GO:1901658	112	0.013
digestive tract morphogenesis	GO:0048546	127	0.013
positive regulation of cell motility	GO:2000147	3	0.013
mesoderm development	GO:0007498	78	0.013
heart morphogenesis	GO:0003007	32	0.013
positive regulation of mapk cascade	GO:0043410	63	0.013
muscle cell differentiation	GO:0042692	103	0.013	Fly
nucleoside triphosphate catabolic process	GO:0009143	108	0.013
positive regulation of developmental growth	GO:0048639	62	0.013
regulation of stress activated mapk cascade	GO:0032872	41	0.013
regulation of stress activated protein kinase signaling cascade	GO:0070302	42	0.013
enteroendocrine cell differentiation	GO:0035883	1	0.013
apoptotic process involved in morphogenesis	GO:0060561	3	0.013
negative regulation of neuron death	GO:1901215	18	0.013
regulation of multi organism process	GO:0043900	131	0.013

Lim3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.074
nervous system disease	DOID:863	0.032
urinary system disease	DOID:18	0.025
sensory system disease	DOID:0050155	0.019
disease of metabolism	DOID:0014667	0.014
eye and adnexa disease	DOID:1492	0.014
disease of cellular proliferation	DOID:14566	0.014
cancer	DOID:162	0.014

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