Drosophila melanogaster

108 known processes

flr (Dmel_CG10724)

flare

(Aliases: CG10724,aip1,Dmel\CG10724,Aip1)

flr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
non sensory hair organizationGO:0035316470.907
imaginal disc derived wing hair organizationGO:0035317450.904
protein depolymerizationGO:0051261310.901
actin filament based processGO:00300292200.814
hair cell differentiationGO:0035315470.803
organelle assemblyGO:00709251980.614
wing disc morphogenesisGO:00074723440.612
actin filament depolymerizationGO:003004250.609
appendage developmentGO:00487364010.577
actin cytoskeleton organizationGO:00300362060.477
negative regulation of notch signaling pathwayGO:0045746410.431
macromolecular complex disassemblyGO:0032984370.384
notch signaling pathwayGO:00072191200.380
imaginal disc derived appendage developmentGO:00487373990.351
regulation of notch signaling pathwayGO:00085931000.341
regulation of actin cytoskeleton organizationGO:0032956420.340
cellular component disassemblyGO:0022411460.335
epidermal cell differentiationGO:0009913510.321
cellular protein complex disassemblyGO:0043624350.304
imaginal disc derived wing morphogenesisGO:00074763370.297
regulation of actin filament depolymerizationGO:003083430.291
spermatogenesisGO:00072832000.278
negative regulation of actin filament depolymerizationGO:003083520.277
intracellular transportGO:00469072280.255
single organism intracellular transportGO:19025822070.235
establishment of imaginal disc derived wing hair orientationGO:0001737240.235
regulation of lamellipodium assemblyGO:0010591150.228
establishment of localization in cellGO:00516494020.228
actin polymerization or depolymerizationGO:0008154310.216
vesicle mediated transportGO:00161923810.206
negative regulation of protein polymerizationGO:003227270.188
appendage morphogenesisGO:00351073970.176
imaginal disc derived appendage morphogenesisGO:00351143950.166
male gamete generationGO:00482322010.166
cellular protein modification processGO:00064644380.163
negative regulation of actin filament polymerizationGO:003083770.162
actin filament organizationGO:00070151260.156
myofibril assemblyGO:0030239360.144
endocytosisGO:00068973100.142
establishment or maintenance of bipolar cell polarityGO:0061245340.137
body morphogenesisGO:001017120.135
regulation of anatomical structure morphogenesisGO:00226032420.133
regulation of proteolysisGO:0030162870.131
protein modification processGO:00362114380.130
negative regulation of signal transductionGO:00099682060.128
imaginal disc derived wing hair site selectionGO:003532040.125
negative regulation of response to stimulusGO:00485852580.123
epidermis developmentGO:0008544650.123
regulation of actin filament based processGO:0032970420.119
establishment of planar polarityGO:0001736870.115
actin filament polymerizationGO:0030041270.115
post embryonic appendage morphogenesisGO:00351203850.114
spermatid developmentGO:0007286980.114
dendrite self avoidanceGO:007059380.113
actin filament cappingGO:005169320.109
regulation of actin filament polymerizationGO:0030833250.101
chromosome organizationGO:00512763600.098
establishment or maintenance of cell polarityGO:00071631670.097
myotube cell developmentGO:001490430.097
imaginal disc derived wing vein morphogenesisGO:0008586440.092
regulation of actin filament lengthGO:0030832270.091
regulation of protein depolymerizationGO:1901879270.089
protein complex disassemblyGO:0043241360.084
negative regulation of signalingGO:00230572190.079
organic substance transportGO:00717022570.079
negative regulation of cell communicationGO:00106482230.077
cellular protein complex assemblyGO:0043623710.075
regulation of organelle organizationGO:00330431960.073
cellular catabolic processGO:00442483720.072
cuticle pattern formationGO:0035017270.072
cellular macromolecular complex assemblyGO:00346221530.071
organelle localizationGO:00516401480.071
regulation of endopeptidase activityGO:0052548360.070
chaeta developmentGO:0022416970.069
cell projection assemblyGO:0030031940.068
positive regulation of signalingGO:00230562430.067
negative regulation of cytoskeleton organizationGO:0051494300.067
regulation of anatomical structure sizeGO:00900661630.067
regulation of actin polymerization or depolymerizationGO:0008064270.066
establishment or maintenance of cytoskeleton polarityGO:0030952440.065
regulation of vesicle mediated transportGO:0060627590.064
muscle cell differentiationGO:00426921030.061
establishment or maintenance of apical basal cell polarityGO:0035088340.061
regulation of multicellular organismal developmentGO:20000264140.059
regulation of dendrite morphogenesisGO:0048814280.059
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.058
regulation of protein metabolic processGO:00512462560.058
establishment of body hair or bristle planar orientationGO:004810460.056
proteasomal protein catabolic processGO:0010498590.055
chaeta morphogenesisGO:0008407420.055
blood circulationGO:0008015260.054
protein polymerizationGO:0051258420.054
cellular component assembly involved in morphogenesisGO:00109271510.054
protein localizationGO:00081042840.053
skin developmentGO:0043588650.053
negative regulation of protein complex disassemblyGO:0043242230.052
protein transportGO:00150311550.051
positive regulation of organelle organizationGO:0010638650.051
regulation of cellular component sizeGO:0032535980.051
protein maturationGO:0051604710.051
mapk cascadeGO:00001651070.050
establishment of proximal distal cell polarityGO:002260640.049
circulatory system developmentGO:0072359820.049
asymmetric cell divisionGO:0008356370.049
synaptic transmissionGO:00072682880.046
regulation of protein complex disassemblyGO:0043244290.046
retina development in camera type eyeGO:006004140.044
positive regulation of wnt signaling pathwayGO:0030177250.044
cilium organizationGO:0044782410.044
protein complex biogenesisGO:00702712010.044
cardiovascular system developmentGO:0072358820.043
spermatid differentiationGO:00485151140.043
wnt signaling pathwayGO:0016055980.043
organic substance catabolic processGO:19015753080.042
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.041
positive regulation of cell communicationGO:00106472500.040
establishment of tissue polarityGO:0007164870.040
ubiquitin dependent protein catabolic processGO:0006511780.040
kidney developmentGO:000182230.040
proteolysis involved in cellular protein catabolic processGO:0051603830.039
phosphorylationGO:00163102940.039
lamellipodium organizationGO:0097581210.038
intracellular signal transductionGO:00355563000.038
apoptotic processGO:00069151590.038
protein complex assemblyGO:00064612000.037
negative regulation of protein depolymerizationGO:1901880230.036
regulation of phosphorylationGO:00423251470.036
regulation of mrna processingGO:0050684710.036
cell divisionGO:00513012480.036
protein modification by small protein conjugationGO:0032446790.036
regulation of cell cycle processGO:00105641810.035
regionalizationGO:00030024160.035
skeletal muscle fiber developmentGO:004874130.035
synaptic vesicle localizationGO:0097479530.035
regulation of cell projection assemblyGO:0060491300.035
regulation of cellular component biogenesisGO:00440872010.034
regulation of neural precursor cell proliferationGO:2000177350.034
oocyte microtubule cytoskeleton polarizationGO:0008103220.034
rhabdomere developmentGO:0042052380.033
cilium assemblyGO:0042384380.033
growthGO:00400073590.033
establishment of organelle localizationGO:00516561220.033
single organism behaviorGO:00447083910.032
macromolecule catabolic processGO:00090571610.032
lamellipodium assemblyGO:0030032210.032
proteolysisGO:00065081920.032
protein processingGO:0016485680.032
atp metabolic processGO:0046034490.032
positive regulation of signal transductionGO:00099672230.032
multicellular organismal agingGO:00102591400.032
regulation of peptidase activityGO:0052547390.031
endosomal transportGO:0016197440.031
establishment of monopolar cell polarityGO:0061162150.031
negative regulation of organelle organizationGO:0010639560.031
regulation of mrna 3 end processingGO:003144070.030
regulation of lamellipodium organizationGO:1902743150.030
female germline ring canal formationGO:000730190.030
sensory perception of chemical stimulusGO:00076061160.030
regulation of proteasomal protein catabolic processGO:0061136390.029
nonmotile primary cilium assemblyGO:003505880.029
modification dependent protein catabolic processGO:0019941780.029
regulation of mitotic cell cycleGO:00073461900.029
intercellular bridge organizationGO:0043063140.028
adult somatic muscle developmentGO:0007527140.028
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.028
phagocytosisGO:00069092150.028
tube developmentGO:00352952440.028
regulation of blood circulationGO:1903522210.027
regulation of cell projection organizationGO:0031344920.027
positive regulation of actin filament polymerizationGO:0030838110.026
cell cycle phase transitionGO:00447701400.026
organonitrogen compound metabolic processGO:19015643180.026
establishment or maintenance of epithelial cell apical basal polarityGO:0045197240.026
circulatory system processGO:0003013370.026
heart contractionGO:0060047260.025
apical constrictionGO:0003383180.025
jnk cascadeGO:0007254500.025
posttranscriptional regulation of gene expressionGO:00106081450.025
asymmetric neuroblast divisionGO:0055059330.025
regulation of protein complex assemblyGO:0043254420.025
regulation of cysteine type endopeptidase activityGO:2000116270.025
epithelial cell differentiationGO:00308553220.024
notch receptor processingGO:0007220130.024
regulation of protein polymerizationGO:0032271280.024
mrna metabolic processGO:00160711240.024
purine nucleoside monophosphate metabolic processGO:0009126500.024
vesicle organizationGO:0016050440.023
regulation of smoothened signaling pathwayGO:0008589280.023
organic acid metabolic processGO:00060821030.023
regulation of canonical wnt signaling pathwayGO:0060828150.023
macromolecular complex assemblyGO:00650032560.023
positive regulation of cellular component organizationGO:00511301560.023
regulation of cell cycleGO:00517262910.023
actin filament based movementGO:0030048260.023
lateral inhibitionGO:00463312060.022
chromosome segregationGO:00070591570.022
regulation of cytoskeleton organizationGO:0051493890.022
antennal morphogenesisGO:0048800140.022
negative regulation of programmed cell deathGO:0043069720.022
antennal developmentGO:0007469250.022
positive regulation of axonogenesisGO:005077220.021
meiotic spindle organizationGO:0000212360.021
establishment of epithelial cell polarityGO:0090162130.021
cellular protein localizationGO:00346131600.021
regulation of molecular functionGO:00650092170.021
protein modification by small protein conjugation or removalGO:00706471060.021
carboxylic acid metabolic processGO:0019752920.021
cell adhesionGO:00071551360.021
regulation of cellular protein metabolic processGO:00322682430.020
striated muscle cell differentiationGO:0051146900.020
regulation of mitotic cell cycle phase transitionGO:19019901300.020
muscle attachmentGO:0016203360.020
neural precursor cell proliferationGO:0061351750.020
regulation of programmed cell deathGO:00430671520.020
morphogenesis of an epitheliumGO:00020092760.020
nephron developmentGO:007200630.020
neuronal action potentialGO:0019228100.020
actin filament bundle organizationGO:0061572280.020
maintenance of protein locationGO:0045185280.020
regulation of cytokinesisGO:003246530.020
organic cyclic compound catabolic processGO:19013611680.020
negative regulation of cellular component organizationGO:00511291080.019
negative regulation of molecular functionGO:0044092510.019
cilium morphogenesisGO:0060271390.019
regulation of apoptotic processGO:00429811300.019
heart developmentGO:0007507820.019
mrna processingGO:00063971040.019
apical junction assemblyGO:0043297320.019
purine ribonucleoside monophosphate metabolic processGO:0009167500.019
nucleus localizationGO:0051647340.019
biological adhesionGO:00226101380.019
muscle organ developmentGO:00075171270.019
ribonucleoside metabolic processGO:00091191270.019
response to temperature stimulusGO:00092661060.019
catabolic processGO:00090564090.019
kidney epithelium developmentGO:007207330.018
protein catabolic processGO:00301631010.018
regulation of cell morphogenesis involved in differentiationGO:0010769610.018
adult behaviorGO:00305341370.018
receptor mediated endocytosisGO:0006898210.018
negative regulation of catalytic activityGO:0043086420.018
positive regulation of response to stimulusGO:00485843230.018
ion transportGO:00068111450.017
regulation of cell morphogenesisGO:00226041630.017
wound healingGO:0042060750.017
cation transportGO:00068121100.017
cellular macromolecule catabolic processGO:00442651360.017
metal ion transportGO:0030001740.017
spinal cord patterningGO:002151110.017
positive regulation of cell migrationGO:003033520.017
cytokinesisGO:0000910900.017
axonal fasciculationGO:0007413120.017
cellularizationGO:0007349900.017
negative regulation of cellular protein metabolic processGO:0032269850.017
modification dependent macromolecule catabolic processGO:0043632790.017
camera type eye developmentGO:004301040.017
single organism catabolic processGO:00447122280.016
ovarian nurse cell to oocyte transportGO:0007300270.016
ribosomal large subunit biogenesisGO:004227310.016
carbohydrate derivative metabolic processGO:19011352170.016
nuclear transportGO:0051169720.016
adherens junction organizationGO:0034332270.016
organelle fusionGO:0048284460.016
actomyosin structure organizationGO:0031032560.016
stress activated mapk cascadeGO:0051403520.016
somatic stem cell divisionGO:0048103370.016
regulation of cellular protein catabolic processGO:1903362440.016
establishment of spindle localizationGO:0051293220.016
morphogenesis of a branching structureGO:0001763450.016
regulation of transportGO:00510491810.016
stress activated protein kinase signaling cascadeGO:0031098550.016
dephosphorylationGO:0016311510.015
regulation of phosphorus metabolic processGO:00511742100.015
regulation of stress activated mapk cascadeGO:0032872410.015
regulation of jnk cascadeGO:0046328400.015
rna 3 end processingGO:0031123450.015
negative regulation of neural precursor cell proliferationGO:2000178270.015
establishment of cell polarityGO:0030010400.015
memoryGO:0007613940.015
oocyte constructionGO:00073081120.015
single organism cellular localizationGO:19025801800.015
axonogenesisGO:00074092900.015
regulation of catalytic activityGO:00507901850.015
regulation of mrna metabolic processGO:1903311720.015
regulation of wnt signaling pathwayGO:0030111680.015
vesicle localizationGO:0051648550.015
branching morphogenesis of an epithelial tubeGO:0048754450.015
nucleoside catabolic processGO:00091641120.015
mushroom body developmentGO:0016319700.014
cytoskeleton dependent cytokinesisGO:0061640810.014
regulation of establishment of planar polarityGO:0090175220.014
defense response to gram negative bacteriumGO:0050829940.014
multi organism behaviorGO:00517051750.014
dorsal ventral pattern formationGO:00099531330.014
protein dephosphorylationGO:0006470270.014
action potentialGO:0001508130.014
positive regulation of establishment of protein localization to plasma membraneGO:009000430.014
negative regulation of cell deathGO:0060548810.014
regulation of cell deathGO:00109411730.014
nucleocytoplasmic transportGO:0006913720.014
regulation of stress activated protein kinase signaling cascadeGO:0070302420.014
mesodermal cell migrationGO:000807870.014
nitrogen compound transportGO:0071705850.014
nucleobase containing compound catabolic processGO:00346551650.014
regulation of endocytosisGO:0030100370.014
determination of adult lifespanGO:00083401370.013
oocyte anterior posterior axis specificationGO:0007314720.013
negative regulation of protein processingGO:0010955310.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.013
spinal cord developmentGO:002151010.013
cellular nitrogen compound catabolic processGO:00442701650.013
negative regulation of cell cycleGO:00457861160.013
hindbrain developmentGO:003090220.013
canonical wnt signaling pathway involved in heart developmentGO:006131630.013
positive regulation of cell projection organizationGO:0031346290.013
cell deathGO:00082192790.013
acid secretionGO:004671710.013
cuticle developmentGO:0042335860.013
ribonucleoside monophosphate metabolic processGO:0009161510.013
positive regulation of macromolecule metabolic processGO:00106044050.013
multicellular organismal signalingGO:0035637120.013
response to alcoholGO:0097305950.013
ameboidal type cell migrationGO:00016671510.013
response to organophosphorusGO:004668320.013
single organism biosynthetic processGO:00447112060.012
cell junction assemblyGO:0034329420.012
intracellular protein transmembrane transportGO:006500240.012
positive regulation of cell motilityGO:200014730.012
germarium derived egg chamber formationGO:00072931010.012
negative regulation of cellular metabolic processGO:00313243820.012
mitotic cell cycle phase transitionGO:00447721380.012
membrane organizationGO:00610241120.012
regulation of protein catabolic processGO:0042176550.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.012
purine nucleotide metabolic processGO:00061631460.012
neuromuscular synaptic transmissionGO:0007274670.012
actin mediated cell contractionGO:0070252210.012
mrna polyadenylationGO:0006378110.012
establishment of nucleus localizationGO:0040023260.012
response to external biotic stimulusGO:00432072930.012
germline ring canal formationGO:0030725130.012
rna localizationGO:00064031150.012
positive regulation of cellular catabolic processGO:0031331950.012
protein ubiquitinationGO:0016567700.011
nephron epithelium developmentGO:007200930.011
tissue morphogenesisGO:00487292970.011
establishment or maintenance of monopolar cell polarityGO:0061339150.011
nucleoside monophosphate metabolic processGO:0009123520.011
regulation of cell shapeGO:00083601130.011
positive regulation of protein localization to plasma membraneGO:190307830.011
positive regulation of protein catabolic processGO:0045732340.011
actin filament bundle assemblyGO:0051017260.011
cellular response to chemical stimulusGO:00708871990.011
signal transduction by phosphorylationGO:00230141070.011
oocyte developmentGO:00485991240.011
larval developmentGO:00021641040.011
cell cell signaling involved in cell fate commitmentGO:00451682100.011
establishment of protein localizationGO:00451841630.011
epithelium migrationGO:00901321480.011
programmed cell deathGO:00125012570.011
intracellular protein transportGO:00068861040.011
compound eye morphogenesisGO:00017452490.011
anterior posterior pattern specificationGO:00099521360.011
positive regulation of canonical wnt signaling pathwayGO:009026370.011
karyosome formationGO:0030717220.011
response to other organismGO:00517072930.011
purine containing compound metabolic processGO:00725211550.011
integrin mediated signaling pathwayGO:000722930.011
rna polyadenylationGO:0043631120.011
morphogenesis of a polarized epitheliumGO:0001738930.011
establishment of synaptic vesicle localizationGO:0097480500.010
cellular homeostasisGO:0019725800.010
embryonic morphogenesisGO:00485982060.010
convergent extensionGO:006002620.010
endomembrane system organizationGO:00102561190.010
nucleotide metabolic processGO:00091171610.010
cell recognitionGO:00080371020.010

flr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.055
nervous system diseaseDOID:86300.029
sensory system diseaseDOID:005015500.016
auditory system diseaseDOID:274200.016
nonsyndromic deafnessDOID:005056300.016
cardiovascular system diseaseDOID:128700.011
artery diseaseDOID:005082800.011
vascular diseaseDOID:17800.011