Drosophila melanogaster

54 known processes

B52 (Dmel_CG10851)

CG10851 gene product from transcript CG10851-RB

(Aliases: SRp55,l(3)s2249,rrm8,RSp55,SR55,B52/SRp55,B52/dSRp55,dSRp55,Rbp8,CG10851,Dmel\CG10851,E726,MabB52,E(Dfd),RRM8)

B52 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell deathGO:00082192790.920
Human
mrna metabolic processGO:00160711240.850
gene silencingGO:00164581380.782
catabolic processGO:00090564090.726
establishment of localization in cellGO:00516494020.700
chromatin assemblyGO:0031497480.665
cellular catabolic processGO:00442483720.657
heterocycle catabolic processGO:00467001660.651
positive regulation of cellular protein metabolic processGO:00322701180.561
posttranscriptional regulation of gene expressionGO:00106081450.551
salivary gland developmentGO:00074311620.527
chromatin assembly or disassemblyGO:0006333520.523
rna splicing via transesterification reactionsGO:0000375730.499
positive regulation of macromolecule metabolic processGO:00106044050.487
intracellular transportGO:00469072280.484
gland developmentGO:00487321910.461
regulation of protein metabolic processGO:00512462560.455
posttranscriptional gene silencingGO:0016441460.450
vesicle mediated transportGO:00161923810.448
rna processingGO:00063961470.431
cellular macromolecule catabolic processGO:00442651360.405
nuclear divisionGO:00002803320.401
gland morphogenesisGO:00226121450.399
negative regulation of gene expression epigeneticGO:0045814770.398
histone acetylationGO:0016573380.389
endocytosisGO:00068973100.385
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.383
regulation of mrna splicing via spliceosomeGO:0048024640.383
regulation of rna splicingGO:0043484690.378
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.375
regulation of mrna processingGO:0050684710.367
positive regulation of biosynthetic processGO:00098913160.360
mitotic nuclear divisionGO:00070672130.344
exocrine system developmentGO:00352721620.330
positive regulation of macromolecule biosynthetic processGO:00105572830.315
tissue deathGO:00162711020.305
autophagyGO:00069141080.300
organelle assemblyGO:00709251980.299
macromolecule catabolic processGO:00090571610.299
regulation of mitotic cell cycleGO:00073461900.288
mrna processingGO:00063971040.288
regulation of alternative mrna splicing via spliceosomeGO:0000381600.274
appendage developmentGO:00487364010.272
histolysisGO:00075591020.266
spindle organizationGO:00070512530.264
positive regulation of rna biosynthetic processGO:19026802660.263
developmental programmed cell deathGO:00106231380.263
regulation of cell differentiationGO:00455953020.257
Human
macromolecular complex assemblyGO:00650032560.256
Human
positive regulation of gene expressionGO:00106282900.255
internal peptidyl lysine acetylationGO:0018393380.249
mitotic spindle organizationGO:00070522200.223
mitotic cell cycle checkpointGO:0007093880.223
negative regulation of signal transductionGO:00099682060.221
central nervous system developmentGO:00074172010.217
deathGO:00162652840.217
Human
positive regulation of nucleic acid templated transcriptionGO:19035082660.217
positive regulation of proteolysisGO:0045862520.216
induction of programmed cell death by ecdysoneGO:0035078120.211
chromatin silencingGO:0006342760.208
gene silencing by rnaGO:0031047570.205
regulation of transcription from rna polymerase ii promoterGO:00063573780.201
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.197
regulation of cellular protein metabolic processGO:00322682430.192
protein dna complex subunit organizationGO:0071824860.189
induction of programmed cell death by hormonesGO:0035081120.184
chemotaxisGO:00069352490.184
positive regulation of cellular biosynthetic processGO:00313283160.182
regulation of gene expression epigeneticGO:00400291280.176
salivary gland morphogenesisGO:00074351450.175
organic substance catabolic processGO:19015753080.171
immune system processGO:00023763470.169
Mouse
posttranscriptional gene silencing by rnaGO:0035194450.164
brain developmentGO:00074201200.162
protein localizationGO:00081042840.161
single organism intracellular transportGO:19025822070.159
neuron projection guidanceGO:00974852410.157
regulation of proteolysisGO:0030162870.156
cellular nitrogen compound catabolic processGO:00442701650.149
mitotic cytokinesisGO:0000281500.149
establishment of organelle localizationGO:00516561220.147
wnt signaling pathwayGO:0016055980.145
positive regulation of protein metabolic processGO:00512471280.144
histone h4 acetylationGO:0043967130.137
aromatic compound catabolic processGO:00194391660.137
positive regulation of endopeptidase activityGO:0010950260.134
regulation of wnt signaling pathwayGO:0030111680.131
negative regulation of cell communicationGO:00106482230.131
rna splicingGO:0008380830.128
regulation of immune effector processGO:0002697520.124
epithelial cell differentiationGO:00308553220.124
Human
male gamete generationGO:00482322010.120
Worm
positive regulation of developmental processGO:00510941430.119
Human Worm
regulation of mrna metabolic processGO:1903311720.118
regulation of cysteine type endopeptidase activityGO:2000116270.110
response to external biotic stimulusGO:00432072930.109
negative regulation of nucleobase containing compound metabolic processGO:00459342610.108
Human
organic substance transportGO:00717022570.108
rna interferenceGO:0016246270.107
negative regulation of developmental processGO:00510932010.105
Human
cell fate specificationGO:0001708710.105
mitotic dna integrity checkpointGO:0044774750.105
negative regulation of signalingGO:00230572190.101
regulation of catalytic activityGO:00507901850.101
ecdysone mediated induction of salivary gland cell autophagic cell deathGO:0035072120.100
positive regulation of nucleobase containing compound metabolic processGO:00459353320.100
regulation of mitotic cell cycle phase transitionGO:19019901300.100
retina development in camera type eyeGO:006004140.099
induction of programmed cell deathGO:0012502120.095
purine ribonucleoside metabolic processGO:00461281270.094
positive regulation of transcription dna templatedGO:00458932660.094
positive regulation of catalytic activityGO:00430851180.094
organonitrogen compound metabolic processGO:19015643180.092
negative regulation of response to stimulusGO:00485852580.091
regulation of mitosisGO:0007088560.091
mrna splicing via spliceosomeGO:0000398730.088
chromatin remodelingGO:0006338720.087
transcription from rna polymerase ii promoterGO:00063663680.087
nucleobase containing compound catabolic processGO:00346551650.086
negative regulation of cellular metabolic processGO:00313243820.086
Human
cellular response to dna damage stimulusGO:00069742230.084
chromatin modificationGO:00165681470.083
regulation of cell developmentGO:00602842150.082
regulation of cell deathGO:00109411730.082
Human
regulation of endopeptidase activityGO:0052548360.080
salivary gland cell autophagic cell deathGO:0035071830.079
cellular amine metabolic processGO:0044106120.078
phagocytosisGO:00069092150.077
regulation of cell fate commitmentGO:0010453290.077
axon developmentGO:00615642970.077
ribonucleoside triphosphate catabolic processGO:00092031080.076
regulation of catabolic processGO:00098941700.076
rna catabolic processGO:0006401370.076
spermatogenesisGO:00072832000.075
Worm
regulation of phosphate metabolic processGO:00192202100.074
forebrain developmentGO:003090020.074
positive regulation of response to stimulusGO:00485843230.074
ncrna metabolic processGO:0034660430.072
organelle fissionGO:00482853400.071
negative regulation of gene expressionGO:00106293870.070
Human
regulation of protein modification processGO:00313991120.070
nucleoside triphosphate metabolic processGO:00091411200.070
regulation of phosphorus metabolic processGO:00511742100.070
regulation of chromatin organizationGO:1902275320.070
eye developmentGO:00016543230.069
regulation of cell cycleGO:00517262910.069
Rat
negative regulation of cell cycle processGO:00109481090.069
negative regulation of protein maturationGO:1903318310.068
regulation of nervous system developmentGO:00519602480.067
cellular response to oxygen containing compoundGO:1901701790.067
phosphorylationGO:00163102940.067
regionalizationGO:00030024160.066
nucleosome mobilizationGO:004276690.065
cellular response to chemical stimulusGO:00708871990.065
dna packagingGO:0006323910.065
salivary gland histolysisGO:0035070880.064
nucleotide metabolic processGO:00091171610.064
response to abiotic stimulusGO:00096283410.064
chromosome separationGO:0051304420.064
autophagic cell deathGO:0048102830.063
canonical wnt signaling pathwayGO:0060070210.063
positive regulation of rna metabolic processGO:00512542710.063
programmed cell deathGO:00125012570.062
proteolysis involved in cellular protein catabolic processGO:0051603830.062
protein complex assemblyGO:00064612000.062
alternative mrna splicing via spliceosomeGO:0000380600.061
ribonucleoside triphosphate metabolic processGO:00091991190.061
peptidyl lysine acetylationGO:0018394390.060
axonogenesisGO:00074092900.059
dna conformation changeGO:00711031050.059
proteolysisGO:00065081920.059
cellular amino acid metabolic processGO:0006520610.058
establishment of protein localizationGO:00451841630.058
apoptotic processGO:00069151590.056
negative regulation of cell differentiationGO:00455961430.056
Human
cellular protein localizationGO:00346131600.055
positive regulation of nitrogen compound metabolic processGO:00511733540.055
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.055
protein complex biogenesisGO:00702712010.054
amine metabolic processGO:0009308120.054
imaginal disc derived appendage developmentGO:00487373990.054
protein maturationGO:0051604710.053
imaginal disc derived wing morphogenesisGO:00074763370.053
axon guidanceGO:00074112330.053
regulation of gene silencingGO:0060968630.052
cytoplasmic transportGO:00164821300.051
regulation of chromosome organizationGO:0033044640.051
protein processingGO:0016485680.050
olfactory behaviorGO:0042048970.049
negative regulation of protein processingGO:0010955310.049
regulation of cellular ketone metabolic processGO:001056530.049
mitotic cell cycle phase transitionGO:00447721380.048
cell migrationGO:00164772380.048
dna integrity checkpointGO:0031570810.048
cell divisionGO:00513012480.047
regulation of cell cycle phase transitionGO:19019871300.047
chromatin organizationGO:00063252070.047
positive regulation of molecular functionGO:00440931360.047
internal protein amino acid acetylationGO:0006475380.047
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051170.046
nucleus organizationGO:0006997450.046
regulation of cellular response to stressGO:0080135890.044
cell motilityGO:00488702510.044
positive regulation of hydrolase activityGO:0051345780.044
protein modification processGO:00362114380.044
cellular macromolecular complex assemblyGO:00346221530.044
Human
ras protein signal transductionGO:0007265880.044
response to biotic stimulusGO:00096072940.043
regulation of multicellular organismal developmentGO:20000264140.043
Human Worm
nucleoside phosphate metabolic processGO:00067531620.043
gtp metabolic processGO:0046039720.042
response to organic substanceGO:00100332840.042
regulation of organ morphogenesisGO:2000027780.042
Human
ribose phosphate metabolic processGO:00196931450.042
regulation of immune system processGO:00026821760.041
compound eye developmentGO:00487493070.041
cognitionGO:00508901410.041
compound eye morphogenesisGO:00017452490.040
mrna splice site selectionGO:000637610.040
Human
single organism nuclear importGO:1902593510.040
regulation of cellular catabolic processGO:00313291570.040
nucleocytoplasmic transportGO:0006913720.038
negative regulation of biosynthetic processGO:00098902770.038
positive regulation of cell deathGO:0010942690.038
nucleosome organizationGO:0034728590.038
purine nucleoside triphosphate catabolic processGO:00091461080.037
histone h3 acetylationGO:0043966110.037
regulation of phosphorylationGO:00423251470.037
activation of cysteine type endopeptidase activityGO:0097202170.036
head developmentGO:00603221350.036
negative regulation of mitotic cell cycle phase transitionGO:19019911030.035
cytoskeleton dependent cytokinesisGO:0061640810.035
ribonucleoprotein complex biogenesisGO:0022613310.035
Human
developmental pigmentationGO:0048066680.034
positive regulation of cell differentiationGO:0045597640.034
regulation of molecular functionGO:00650092170.034
positive regulation of signalingGO:00230562430.034
intracellular protein transportGO:00068861040.033
appendage morphogenesisGO:00351073970.033
regulation of cellular amine metabolic processGO:003323830.032
regulation of response to stressGO:00801342000.032
Human
covalent chromatin modificationGO:00165691060.032
development of primary sexual characteristicsGO:0045137500.032
Worm
chromosome organizationGO:00512763600.032
regulation of cellular amino acid metabolic processGO:000652100.031
taxisGO:00423303040.031
mitotic g2 m transition checkpointGO:0044818700.031
mitotic dna damage checkpointGO:0044773740.031
positive regulation of peptidase activityGO:0010952290.030
protein modification by small protein removalGO:0070646280.030
purine nucleoside metabolic processGO:00422781270.030
negative regulation of mitotic cell cycleGO:00459301090.030
regulation of multi organism processGO:00439001310.029
muscle structure developmentGO:00610612240.029
purine ribonucleotide catabolic processGO:00091541090.029
dna damage checkpointGO:0000077780.029
regulation of neurogenesisGO:00507671580.029
regulation of cellular protein catabolic processGO:1903362440.029
small molecule metabolic processGO:00442813050.028
regulation of protein catabolic processGO:0042176550.028
regulation of anatomical structure morphogenesisGO:00226032420.028
Human
intracellular steroid hormone receptor signaling pathwayGO:0030518120.028
enzyme linked receptor protein signaling pathwayGO:00071671790.028
regulation of cellular localizationGO:00603411360.028
purine containing compound metabolic processGO:00725211550.028
macromolecular complex disassemblyGO:0032984370.028
protein acetylationGO:0006473390.028
morphogenesis of a polarized epitheliumGO:0001738930.028
sex differentiationGO:0007548810.027
Worm
dna metabolic processGO:00062592270.027
regulation of organelle organizationGO:00330431960.027
ribosome biogenesisGO:004225480.027
small gtpase mediated signal transductionGO:0007264880.027
modification dependent protein catabolic processGO:0019941780.027
regulation of chromosome segregationGO:0051983320.027
protein catabolic processGO:00301631010.027
translational initiationGO:0006413110.027
positive regulation of cell communicationGO:00106472500.026
reproductive system developmentGO:0061458740.026
Worm
protein acylationGO:0043543420.026
localization of cellGO:00516742570.026
nucleoside phosphate catabolic processGO:19012921100.025
multi organism behaviorGO:00517051750.025
ribonucleoside metabolic processGO:00091191270.025
biological adhesionGO:00226101380.025
imaginal disc derived appendage morphogenesisGO:00351143950.024
dna endoreduplicationGO:0042023220.024
eye morphogenesisGO:00485922600.024
organophosphate metabolic processGO:00196371950.024
glycosyl compound metabolic processGO:19016571270.024
regulation of peptidase activityGO:0052547390.024
negative regulation of cell cycle phase transitionGO:19019881030.024
actin cytoskeleton organizationGO:00300362060.024
cellular protein catabolic processGO:0044257830.024
genitalia developmentGO:0048806260.024
Worm
regulation of proteasomal protein catabolic processGO:0061136390.024
retina morphogenesis in camera type eyeGO:006004220.023
positive regulation of phosphate metabolic processGO:00459371390.023
g2 dna damage checkpointGO:0031572690.023
cell cell signaling involved in cell fate commitmentGO:00451682100.023
peptidyl lysine modificationGO:0018205570.023
ribonucleoside catabolic processGO:00424541120.023
nucleosome assemblyGO:0006334350.022
cytokinesisGO:0000910900.022
ribonucleotide catabolic processGO:00092611090.022
purine ribonucleoside triphosphate metabolic processGO:00092051190.021
histone modificationGO:00165701060.021
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.021
sensory organ morphogenesisGO:00905962600.021
limb developmentGO:006017310.021
positive regulation of cell developmentGO:0010720610.021
nucleoside metabolic processGO:00091161270.020
positive regulation of cysteine type endopeptidase activityGO:2001056240.020
organic cyclic compound catabolic processGO:19013611680.020
negative regulation of chromosome segregationGO:0051985140.020
response to ecdysoneGO:0035075340.020
negative regulation of proteasomal protein catabolic processGO:1901799160.020
purine ribonucleoside triphosphate catabolic processGO:00092071080.020
purine ribonucleotide metabolic processGO:00091501450.020
positive regulation of growthGO:0045927750.019
negative regulation of catabolic processGO:0009895360.019
positive regulation of signal transductionGO:00099672230.019
protein phosphorylationGO:00064681690.019
neural retina developmentGO:000340740.019
mitotic g2 dna damage checkpointGO:0007095690.018
regulation of mitotic sister chromatid separationGO:0010965280.018
single organism cellular localizationGO:19025801800.018
ncrna processingGO:0034470300.018
regulation of growthGO:00400082330.018
Worm
response to other organismGO:00517072930.018
positive regulation of translationGO:0045727120.018
regulation of cell cycle processGO:00105641810.018
regulation of hydrolase activityGO:0051336970.017
cellular response to decreased oxygen levelsGO:0036294300.017
exocytosisGO:0006887280.017
cellular component disassemblyGO:0022411460.017
regulation of notch signaling pathwayGO:00085931000.017
dorsal ventral pattern formationGO:00099531330.017
regulation of translationGO:0006417560.016
spermatid differentiationGO:00485151140.016
muscle organ developmentGO:00075171270.016
negative regulation of nucleic acid templated transcriptionGO:19035072400.016
purine nucleotide metabolic processGO:00061631460.016
negative regulation of rna biosynthetic processGO:19026792400.016
guanosine containing compound metabolic processGO:1901068740.016
camera type eye developmentGO:004301040.016
mapk cascadeGO:00001651070.016
dendrite developmentGO:00163582040.016
nucleobase containing small molecule metabolic processGO:00550861740.016
cell cycle checkpointGO:0000075950.016
apoptotic signaling pathwayGO:0097190270.016
positive regulation of mapk cascadeGO:0043410630.015
regulation of intracellular signal transductionGO:19025312360.015
regulation of protein processingGO:0070613320.015
meiotic nuclear divisionGO:00071261510.015
branch fusion open tracheal systemGO:0035147170.015
protein dna complex assemblyGO:0065004630.015
purine nucleoside triphosphate metabolic processGO:00091441190.015
regulation of chromatin silencingGO:0031935360.015
regulation of heterochromatin assemblyGO:003144580.015
positive regulation of intracellular signal transductionGO:19025331160.014
body morphogenesisGO:001017120.014
Worm
hindbrain developmentGO:003090220.014
telencephalon developmentGO:002153720.014
positive regulation of multi organism processGO:0043902400.014
glycosyl compound catabolic processGO:19016581120.014
negative regulation of cell cycleGO:00457861160.014
regulation of ras protein signal transductionGO:0046578930.014
ameboidal type cell migrationGO:00016671510.014
negative regulation of protein catabolic processGO:0042177170.014
camera type eye morphogenesisGO:004859320.014
gonad developmentGO:0008406500.013
Worm
nucleoside triphosphate catabolic processGO:00091431080.013
meiotic cell cycle processGO:19030461320.013
membrane organizationGO:00610241120.013
nucleotide catabolic processGO:00091661090.013
positive regulation of nervous system developmentGO:0051962690.013
pupal developmentGO:0035209110.013
purine nucleoside catabolic processGO:00061521120.013
positive regulation of cellular amine metabolic processGO:003324000.013
regulation of programmed cell deathGO:00430671520.013
single organism carbohydrate metabolic processGO:0044723720.013
purine nucleotide catabolic processGO:00061951090.013
carbohydrate derivative catabolic processGO:19011361180.012
response to sterolGO:0036314340.012
golgi vesicle transportGO:0048193270.012
carboxylic acid metabolic processGO:0019752920.012
developmental growthGO:00485892800.012
carbohydrate metabolic processGO:0005975820.012
guanosine containing compound catabolic processGO:1901069740.012
antimicrobial humoral responseGO:0019730990.012
chemosensory behaviorGO:00076351060.012
single organism catabolic processGO:00447122280.012
regulation of meiosisGO:004002030.012
chromosome segregationGO:00070591570.012
memoryGO:0007613940.012
convergent extensionGO:006002620.011
regulation of chromatin modificationGO:1903308280.011
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.011
protein heterooligomerizationGO:005129140.011
eye photoreceptor cell differentiationGO:00017541450.011
negative regulation of cellular catabolic processGO:0031330340.011
regulation of localizationGO:00328792750.011
organic acid metabolic processGO:00060821030.011
tube fusionGO:0035146170.011
protein transportGO:00150311550.011
negative regulation of proteolysisGO:0045861310.011
cell cycle dna replicationGO:0044786230.011
neuron fate commitmentGO:0048663500.011
negative regulation of rna metabolic processGO:00512532510.011
Human
histone h4 k16 acetylationGO:004398440.011
cell fate determinationGO:0001709910.011
single organism behaviorGO:00447083910.011
cellular ketone metabolic processGO:0042180240.011
transcription from rna polymerase iii promoterGO:000638380.011
multicellular organismal reproductive behaviorGO:00330571100.011
modification dependent macromolecule catabolic processGO:0043632790.010
regulation of protein maturationGO:1903317320.010
nuclear body organizationGO:003057560.010
establishment of protein localization to organelleGO:0072594620.010
spermatid developmentGO:0007286980.010
meiosis iGO:0007127590.010
regulation of response to biotic stimulusGO:0002831630.010

B52 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
nervous system diseaseDOID:86300.036
disease of cellular proliferationDOID:1456600.027