Drosophila melanogaster

41 known processes

Clic (Dmel_CG10997)

Chloride intracellular channel

(Aliases: DmCLIC,l(1)G0053,CG10997,DCLIC,Dmel\CG10997,l(1)G0472)

Clic biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
gravitaxisGO:0042332260.330
wing disc morphogenesisGO:00074723440.280
imaginal disc derived appendage morphogenesisGO:00351143950.232
adult behaviorGO:00305341370.210
intracellular transportGO:00469072280.187
post embryonic appendage morphogenesisGO:00351203850.186
imaginal disc derived appendage developmentGO:00487373990.145
cellular macromolecule localizationGO:00707272200.139
appendage developmentGO:00487364010.121
taxisGO:00423303040.117
cellular protein modification processGO:00064644380.101
establishment of localization in cellGO:00516494020.098
vesicle mediated transportGO:00161923810.091
intracellular signal transductionGO:00355563000.090
locomotory behaviorGO:00076261760.089
imaginal disc derived wing morphogenesisGO:00074763370.085
response to abiotic stimulusGO:00096283410.084
endocytosisGO:00068973100.075
cellular protein localizationGO:00346131600.074
single organism intracellular transportGO:19025822070.072
appendage morphogenesisGO:00351073970.071
protein localizationGO:00081042840.071
Mouse
synapse organizationGO:00508081960.070
regulation of anatomical structure morphogenesisGO:00226032420.069
dorsal closureGO:0007391790.068
cuticle pigmentationGO:0048067220.067
organelle assemblyGO:00709251980.066
tissue morphogenesisGO:00487292970.066
Mouse
single organism catabolic processGO:00447122280.065
actin filament based processGO:00300292200.065
morphogenesis of embryonic epitheliumGO:0016331940.061
single organism cellular localizationGO:19025801800.061
synaptic transmissionGO:00072682880.060
cytoplasmic transportGO:00164821300.059
cell projection assemblyGO:0030031940.058
positive regulation of phosphate metabolic processGO:00459371390.058
macromolecular complex assemblyGO:00650032560.057
protein transportGO:00150311550.056
regulation of phosphate metabolic processGO:00192202100.055
regulation of phosphorus metabolic processGO:00511742100.054
open tracheal system developmentGO:00074242040.053
establishment of protein localizationGO:00451841630.053
respiratory system developmentGO:00605412130.051
regulation of cell shapeGO:00083601130.049
cellular catabolic processGO:00442483720.048
negative regulation of response to stimulusGO:00485852580.047
pigmentationGO:0043473750.047
organophosphate catabolic processGO:00464341120.046
developmental pigmentationGO:0048066680.045
adult chitin containing cuticle pigmentationGO:0048085160.045
positive regulation of phosphorus metabolic processGO:00105621390.044
microtubule based movementGO:0007018510.044
positive regulation of response to stimulusGO:00485843230.044
protein modification processGO:00362114380.044
regulation of anatomical structure sizeGO:00900661630.044
response to gravityGO:0009629260.043
regulation of localizationGO:00328792750.042
defense response to other organismGO:00985422250.042
regulation of cell morphogenesisGO:00226041630.041
ribonucleoside triphosphate catabolic processGO:00092031080.041
photoreceptor cell differentiationGO:00465301700.040
positive regulation of cell sizeGO:0045793210.040
adult locomotory behaviorGO:0008344760.040
positive regulation of signalingGO:00230562430.039
ras protein signal transductionGO:0007265880.038
positive regulation of cell communicationGO:00106472500.038
proteolysisGO:00065081920.037
small gtpase mediated signal transductionGO:0007264880.037
homeostatic processGO:00425921990.037
Mouse
organic substance transportGO:00717022570.037
cilium morphogenesisGO:0060271390.037
protein complex biogenesisGO:00702712010.036
immune system processGO:00023763470.036
embryonic morphogenesisGO:00485982060.035
Mouse
transcription from rna polymerase ii promoterGO:00063663680.035
regulation of mapk cascadeGO:0043408920.035
response to bacteriumGO:00096171980.034
eye developmentGO:00016543230.033
Mouse
organelle localizationGO:00516401480.033
regulation of cellular protein metabolic processGO:00322682430.033
organophosphate metabolic processGO:00196371950.032
nucleoside phosphate catabolic processGO:19012921100.032
catabolic processGO:00090564090.032
negative regulation of cell communicationGO:00106482230.032
regulation of catalytic activityGO:00507901850.032
regulation of phosphorylationGO:00423251470.032
regulation of notch signaling pathwayGO:00085931000.032
positive regulation of nucleobase containing compound metabolic processGO:00459353320.031
head developmentGO:00603221350.031
positive regulation of phosphorylationGO:0042327870.031
positive regulation of nitrogen compound metabolic processGO:00511733540.031
phagocytosisGO:00069092150.031
axonogenesisGO:00074092900.031
stress activated protein kinase signaling cascadeGO:0031098550.030
cytoskeleton dependent intracellular transportGO:0030705440.030
defense responseGO:00069523000.029
regulation of molecular functionGO:00650092170.029
notch signaling pathwayGO:00072191200.029
chemical homeostasisGO:0048878920.028
Mouse
regulation of mitotic cell cycleGO:00073461900.028
heterocycle catabolic processGO:00467001660.028
ribose phosphate metabolic processGO:00196931450.028
epithelial cell developmentGO:00020642740.028
Mouse
phosphorylationGO:00163102940.028
regulation of growthGO:00400082330.028
membrane organizationGO:00610241120.028
regulation of cell cycleGO:00517262910.027
positive regulation of signal transductionGO:00099672230.027
rho protein signal transductionGO:0007266140.027
organonitrogen compound metabolic processGO:19015643180.027
regulation of intracellular signal transductionGO:19025312360.027
regulation of response to stressGO:00801342000.027
regulation of adult chitin containing cuticle pigmentationGO:0048082130.027
lateral inhibitionGO:00463312060.027
microtubule based transportGO:0010970420.027
nucleobase containing small molecule metabolic processGO:00550861740.026
cytoskeleton dependent cytokinesisGO:0061640810.026
embryo development ending in birth or egg hatchingGO:00097921520.026
intracellular protein transportGO:00068861040.026
glycosyl compound catabolic processGO:19016581120.026
cation transportGO:00068121100.026
purine ribonucleotide metabolic processGO:00091501450.026
regulation of synapse organizationGO:00508071100.025
organic cyclic compound catabolic processGO:19013611680.025
positive regulation of biosynthetic processGO:00098913160.025
single organism behaviorGO:00447083910.025
positive regulation of molecular functionGO:00440931360.025
nucleoside phosphate metabolic processGO:00067531620.025
axon guidanceGO:00074112330.024
biological adhesionGO:00226101380.024
response to light stimulusGO:00094161240.024
carbohydrate derivative metabolic processGO:19011352170.024
nucleotide metabolic processGO:00091171610.024
signal transduction in response to dna damageGO:004277030.023
positive regulation of macromolecule biosynthetic processGO:00105572830.023
purine ribonucleoside triphosphate catabolic processGO:00092071080.023
regulation of cell developmentGO:00602842150.023
regulation of cellular component biogenesisGO:00440872010.023
regulation of protein modification processGO:00313991120.022
nucleoside catabolic processGO:00091641120.022
cell adhesionGO:00071551360.022
cellular macromolecular complex assemblyGO:00346221530.022
muscle structure developmentGO:00610612240.022
tube developmentGO:00352952440.022
Mouse
regulation of cellular amine metabolic processGO:003323830.021
regulation of transcription from rna polymerase ii promoterGO:00063573780.021
regulation of developmental growthGO:00486381740.021
growthGO:00400073590.021
Mouse
regionalizationGO:00030024160.021
single organism membrane organizationGO:0044802930.021
skeletal muscle fiber developmentGO:004874130.021
organic substance catabolic processGO:19015753080.021
secretionGO:00469031090.020
positive regulation of macromolecule metabolic processGO:00106044050.020
nuclear transportGO:0051169720.020
nucleobase containing compound catabolic processGO:00346551650.020
establishment of organelle localizationGO:00516561220.020
neurological system processGO:00508773580.020
Mouse
purine containing compound metabolic processGO:00725211550.020
intracellular mrna localization involved in pattern specification processGO:0060810560.020
positive regulation of transportGO:0051050920.020
developmental growthGO:00485892800.020
positive regulation of catalytic activityGO:00430851180.020
nucleotide catabolic processGO:00091661090.020
sensory perception of mechanical stimulusGO:0050954720.020
Mouse
developmental maturationGO:00217001720.019
programmed cell deathGO:00125012570.019
purine nucleoside triphosphate catabolic processGO:00091461080.019
regulation of cell sizeGO:0008361630.019
maternal determination of anterior posterior axis embryoGO:0008358740.019
embryonic development via the syncytial blastodermGO:00017001480.019
embryonic pattern specificationGO:00098801740.019
regulation of protein metabolic processGO:00512462560.019
immune responseGO:00069552460.019
membrane fusionGO:0061025420.019
positive regulation of protein metabolic processGO:00512471280.019
aromatic compound catabolic processGO:00194391660.019
golgi localizationGO:005164520.019
actin filament organizationGO:00070151260.018
morphogenesis of an epitheliumGO:00020092760.018
Mouse
regulation of transportGO:00510491810.018
chemotaxisGO:00069352490.018
regulation of cuticle pigmentationGO:0048079160.018
positive regulation of mapk cascadeGO:0043410630.018
eggshell formationGO:00307031050.018
cellular homeostasisGO:0019725800.018
Mouse
dna damage checkpointGO:0000077780.018
response to nutrient levelsGO:00316671140.018
Mouse
regulation of organelle organizationGO:00330431960.018
cellular component assembly involved in morphogenesisGO:00109271510.018
small molecule metabolic processGO:00442813050.017
regulation of cellular localizationGO:00603411360.017
nucleocytoplasmic transportGO:0006913720.017
gland morphogenesisGO:00226121450.017
metal ion transportGO:0030001740.017
cell junction assemblyGO:0034329420.017
regulation of tube architecture open tracheal systemGO:0035152680.017
regulation of synapse structure and activityGO:00508031280.017
chitin based cuticle sclerotizationGO:0007593190.017
cell growthGO:00160491080.017
positive regulation of protein transportGO:0051222370.017
regulation of jnk cascadeGO:0046328400.017
negative regulation of signal transductionGO:00099682060.017
nucleoside monophosphate catabolic processGO:0009125390.017
protein localization to organelleGO:0033365820.017
response to hexoseGO:000974630.017
ion transmembrane transportGO:00342201220.016
cell maturationGO:00484691440.016
regulation of cellular component sizeGO:0032535980.016
initiation of dorsal closureGO:0007392120.016
vesicle organizationGO:0016050440.016
rna processingGO:00063961470.016
oocyte differentiationGO:00099941450.016
regulation of immune system processGO:00026821760.016
macromolecule catabolic processGO:00090571610.016
detection of stimulusGO:00516061560.016
cellular carbohydrate metabolic processGO:0044262220.016
regulation of hydrolase activityGO:0051336970.016
positive regulation of cellular amine metabolic processGO:003324000.016
regulation of intracellular transportGO:0032386640.016
camera type eye developmentGO:004301040.016
Mouse
eye morphogenesisGO:00485922600.016
cilium organizationGO:0044782410.015
compound eye developmentGO:00487493070.015
response to organic substanceGO:00100332840.015
negative regulation of cellular metabolic processGO:00313243820.015
carbohydrate derivative catabolic processGO:19011361180.015
ribonucleotide metabolic processGO:00092591450.015
sensory perceptionGO:00076001960.015
Mouse
nucleoside triphosphate catabolic processGO:00091431080.015
ph reductionGO:004585170.015
Mouse
establishment of protein localization to organelleGO:0072594620.015
hippo signalingGO:0035329200.015
regulation of cellular catabolic processGO:00313291570.015
regulation of cellular amino acid metabolic processGO:000652100.015
cell cell signaling involved in cell fate commitmentGO:00451682100.015
eye photoreceptor cell differentiationGO:00017541450.015
ion transportGO:00068111450.015
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.015
response to heatGO:0009408630.015
positive regulation of gene expressionGO:00106282900.014
mapk cascadeGO:00001651070.014
purine containing compound catabolic processGO:00725231120.014
peptidyl amino acid modificationGO:00181931050.014
protein catabolic processGO:00301631010.014
positive regulation of hydrolase activityGO:0051345780.014
response to other organismGO:00517072930.014
purine nucleotide metabolic processGO:00061631460.014
defense response to gram negative bacteriumGO:0050829940.014
maintenance of locationGO:0051235730.014
segmentationGO:00352822070.014
positive regulation of intracellular signal transductionGO:19025331160.014
regulation of stress activated protein kinase signaling cascadeGO:0070302420.014
muscle attachmentGO:0016203360.014
jnk cascadeGO:0007254500.014
innate immune responseGO:00450871440.014
negative regulation of programmed cell deathGO:0043069720.014
positive regulation of protein modification processGO:0031401580.014
immune response activating signal transductionGO:000275720.014
negative regulation of developmental processGO:00510932010.014
positive regulation of developmental growthGO:0048639620.014
actin cytoskeleton organizationGO:00300362060.014
dephosphorylationGO:0016311510.014
stress activated mapk cascadeGO:0051403520.014
imaginal disc fusionGO:0046528190.013
regulation of cellular response to stressGO:0080135890.013
negative regulation of cell differentiationGO:00455961430.013
central nervous system developmentGO:00074172010.013
gastrulation with mouth forming firstGO:0001703360.013
single organism biosynthetic processGO:00447112060.013
regulation of intracellular protein transportGO:0033157460.013
anterior posterior axis specification embryoGO:00085951030.013
endomembrane system organizationGO:00102561190.013
spermatid developmentGO:0007286980.013
positive regulation of cellular biosynthetic processGO:00313283160.013
regulation of nucleocytoplasmic transportGO:0046822350.013
regulation of cell cycle processGO:00105641810.013
localization of cellGO:00516742570.013
purine ribonucleoside metabolic processGO:00461281270.013
purine nucleoside catabolic processGO:00061521120.013
erk1 and erk2 cascadeGO:0070371390.013
pole plasm assemblyGO:0007315610.013
regulation of ras protein signal transductionGO:0046578930.013
protein dna complex subunit organizationGO:0071824860.013
establishment of nucleus localizationGO:0040023260.013
regulation of protein localizationGO:0032880760.013
oocyte constructionGO:00073081120.013
regulation of transferase activityGO:0051338580.013
cell divisionGO:00513012480.013
ovarian follicle cell developmentGO:00307072480.013
phagosome acidificationGO:009038310.013
multi organism reproductive behaviorGO:00447051210.013
positive regulation of cellular protein metabolic processGO:00322701180.013
regulation of chitin based cuticle tanningGO:0007564140.013
kidney developmentGO:000182230.012
positive regulation of nucleic acid templated transcriptionGO:19035082660.012
positive regulation of growthGO:0045927750.012
molting cycleGO:0042303560.012
chromatin silencingGO:0006342760.012
regulation of tube size open tracheal systemGO:0035151430.012
negative regulation of phosphorus metabolic processGO:0010563450.012
anterior posterior pattern specificationGO:00099521360.012
response to radiationGO:00093141550.012
protein importGO:0017038550.012
anatomical structure homeostasisGO:0060249970.012
cellular response to dna damage stimulusGO:00069742230.012
negative regulation of intracellular signal transductionGO:1902532570.012
response to biotic stimulusGO:00096072940.012
response to glucoseGO:000974920.012
cell deathGO:00082192790.012
single organism carbohydrate metabolic processGO:0044723720.012
regulation of protein transportGO:0051223570.012
collateral sproutingGO:004866830.012
gene silencingGO:00164581380.012
ribonucleotide catabolic processGO:00092611090.012
positive regulation of cellular component organizationGO:00511301560.012
multicellular organismal reproductive behaviorGO:00330571100.012
multi multicellular organism processGO:00447061230.012
smoothened signaling pathwayGO:0007224490.012
apoptotic processGO:00069151590.012
cytokinesisGO:0000910900.012
protein phosphorylationGO:00064681690.012
positive regulation of ras protein signal transductionGO:0046579430.012
detection of light stimulusGO:0009583580.012
ion homeostasisGO:0050801550.012
Mouse
positive regulation of cell migrationGO:003033520.012
response to external biotic stimulusGO:00432072930.012
dna integrity checkpointGO:0031570810.012
purine ribonucleotide catabolic processGO:00091541090.012
protein complex assemblyGO:00064612000.012
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.012
regulation of establishment of protein localizationGO:0070201610.012
nuclear migrationGO:0007097200.011
ribonucleoside catabolic processGO:00424541120.011
digestive system developmentGO:00551231490.011
posttranscriptional regulation of gene expressionGO:00106081450.011
cell cell junction assemblyGO:0007043380.011
hemocyte migrationGO:0035099190.011
compound eye photoreceptor developmentGO:0042051780.011
maintenance of protein locationGO:0045185280.011
renal filtrationGO:009720570.011
circulatory system processGO:0003013370.011
ribonucleoside monophosphate catabolic processGO:0009158390.011
response to lipopolysaccharideGO:003249640.011
nephron developmentGO:007200630.011
positive regulation of cell projection organizationGO:0031346290.011
cilium assemblyGO:0042384380.011
cortical actin cytoskeleton organizationGO:0030866240.011
regulation of cellular phGO:003064170.011
Mouse
organelle fissionGO:00482853400.011
negative regulation of growthGO:0045926840.011
positive regulation of intracellular transportGO:0032388420.011
outflow tract morphogenesisGO:000315140.011
positive regulation of cellular catabolic processGO:0031331950.011
protein targetingGO:0006605640.011
negative regulation of phosphate metabolic processGO:0045936450.011
signal transduction by phosphorylationGO:00230141070.011
eye pigmentationGO:0048069430.011
larval developmentGO:00021641040.011
compound eye morphogenesisGO:00017452490.011
neuromuscular junction developmentGO:00075281490.011
histone h4 k16 acetylationGO:004398440.010
transmembrane transportGO:00550851390.010
pyridine containing compound metabolic processGO:007252430.010
regulation of lipid storageGO:0010883220.010
immune response regulating signaling pathwayGO:000276420.010
cellular amine metabolic processGO:0044106120.010
protein import into nucleusGO:0006606510.010
regulation of cytoplasmic transportGO:1903649470.010
regulation of neuron differentiationGO:00456641030.010
cell agingGO:000756920.010
organelle fusionGO:0048284460.010
rrna processingGO:000636430.010
nuclear divisionGO:00002803320.010
positive regulation of erk1 and erk2 cascadeGO:0070374360.010
amine metabolic processGO:0009308120.010
sensory perception of painGO:001923340.010
cellular monovalent inorganic cation homeostasisGO:003000470.010
Mouse
membrane depolarizationGO:005189940.010

Clic disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
nervous system diseaseDOID:86300.022
eye diseaseDOID:561400.014
eye and adnexa diseaseDOID:149200.014
sensory system diseaseDOID:005015500.014