Drosophila melanogaster

142 known processes

dsx (Dmel_CG11094)

doublesex

(Aliases: DSX,Dsx,ix-62c,CG11094,Dmdsx,Hr,Dmel\CG11094)

dsx biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of biosynthetic processGO:00098902770.989
multicellular organismal reproductive behaviorGO:00330571100.973
male courtship behaviorGO:0008049630.965
reproductive behaviorGO:00190981220.955
positive regulation of nitrogen compound metabolic processGO:00511733540.954
regulation of imaginal disc derived wing sizeGO:0044719200.943
negative regulation of cellular biosynthetic processGO:00313272770.942
male courtship behavior veined wing generated song productionGO:0045433200.934
male courtship behavior veined wing extensionGO:0048065220.923
positive regulation of macromolecule biosynthetic processGO:00105572830.918
positive regulation of rna metabolic processGO:00512542710.907
single organism behaviorGO:00447083910.904
negative regulation of gene expressionGO:00106293870.904
mating behaviorGO:00076171060.895
male mating behaviorGO:0060179700.890
male courtship behavior veined wing vibrationGO:0016545210.888
regulation of transcription from rna polymerase ii promoterGO:00063573780.882
embryonic morphogenesisGO:00485982060.853
multi multicellular organism processGO:00447061230.843
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.827
positive regulation of gene expressionGO:00106282900.813
transcription from rna polymerase ii promoterGO:00063663680.789
positive regulation of cellular biosynthetic processGO:00313283160.785
positive regulation of nucleic acid templated transcriptionGO:19035082660.781
positive regulation of transcription dna templatedGO:00458932660.763
multi organism reproductive behaviorGO:00447051210.708
response to organic substanceGO:00100332840.686
photoreceptor cell differentiationGO:00465301700.659
negative regulation of nitrogen compound metabolic processGO:00511722650.656
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.651
negative regulation of developmental processGO:00510932010.637
immune system processGO:00023763470.616
matingGO:00076181200.604
positive regulation of biosynthetic processGO:00098913160.603
cell migrationGO:00164772380.591
Mouse
positive regulation of rna biosynthetic processGO:19026802660.582
courtship behaviorGO:0007619680.582
germ cell migrationGO:0008354430.576
Mouse
tube developmentGO:00352952440.567
positive regulation of nucleobase containing compound metabolic processGO:00459353320.547
male sex differentiationGO:0046661250.537
Mouse
photoreceptor cell developmentGO:0042461960.535
eye developmentGO:00016543230.534
eye photoreceptor cell differentiationGO:00017541450.519
multi organism behaviorGO:00517051750.501
negative regulation of transcription dna templatedGO:00458922370.496
digestive tract developmentGO:00485651490.480
taxisGO:00423303040.467
tissue morphogenesisGO:00487292970.416
appendage morphogenesisGO:00351073970.406
locomotory behaviorGO:00076261760.396
neurological system processGO:00508773580.373
camera type eye developmentGO:004301040.330
cellular response to organic substanceGO:00713101320.320
response to organic cyclic compoundGO:0014070890.319
regionalizationGO:00030024160.308
chemotaxisGO:00069352490.294
eye photoreceptor cell developmentGO:0042462810.288
negative regulation of cellular metabolic processGO:00313243820.285
blastoderm segmentationGO:00073501590.284
camera type eye morphogenesisGO:004859320.284
apoptotic processGO:00069151590.283
sensory organ morphogenesisGO:00905962600.275
negative regulation of nucleobase containing compound metabolic processGO:00459342610.270
enzyme linked receptor protein signaling pathwayGO:00071671790.261
Mouse
response to oxygen containing compoundGO:19017002000.243
organonitrogen compound metabolic processGO:19015643180.242
cellular response to chemical stimulusGO:00708871990.236
digestive system developmentGO:00551231490.236
regulation of molecular functionGO:00650092170.232
embryonic development via the syncytial blastodermGO:00017001480.228
imaginal disc derived female genitalia developmentGO:000748660.220
response to other organismGO:00517072930.217
defense responseGO:00069523000.215
intracellular signal transductionGO:00355563000.214
axon developmentGO:00615642970.211
wing disc morphogenesisGO:00074723440.211
cell motilityGO:00488702510.207
Mouse
anterior posterior axis specificationGO:00099481090.205
developmental programmed cell deathGO:00106231380.205
mesenchyme developmentGO:006048590.204
axonogenesisGO:00074092900.199
compound eye developmentGO:00487493070.198
regulation of transportGO:00510491810.198
mesoderm developmentGO:0007498780.197
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.194
deathGO:00162652840.192
neuron projection guidanceGO:00974852410.188
purine containing compound metabolic processGO:00725211550.188
adult chitin containing cuticle pigmentationGO:0048085160.182
localization of cellGO:00516742570.181
Mouse
multicellular organismal homeostasisGO:0048871410.178
segmentationGO:00352822070.172
dendrite developmentGO:00163582040.171
torso signaling pathwayGO:0008293210.171
response to endogenous stimulusGO:00097191190.152
response to oxidative stressGO:0006979860.150
dorsal ventral pattern formationGO:00099531330.147
homeostatic processGO:00425921990.144
leg disc developmentGO:0035218920.142
zygotic determination of anterior posterior axis embryoGO:0007354270.141
digestive tract morphogenesisGO:00485461270.140
morphogenesis of an epitheliumGO:00020092760.136
central nervous system developmentGO:00074172010.136
regulation of cell differentiationGO:00455953020.135
learning or memoryGO:00076111410.133
sensory perceptionGO:00076001960.130
response to alcoholGO:0097305950.129
imaginal disc derived appendage morphogenesisGO:00351143950.129
mesodermal cell fate specificationGO:000750120.127
cellular response to endogenous stimulusGO:0071495800.127
negative regulation of cell fate specificationGO:0009996150.125
embryonic pattern specificationGO:00098801740.124
epithelial cell migration open tracheal systemGO:0007427320.123
compound eye morphogenesisGO:00017452490.123
imaginal disc derived appendage developmentGO:00487373990.123
negative regulation of response to stimulusGO:00485852580.123
mesoderm morphogenesisGO:0048332220.123
anterior posterior pattern specificationGO:00099521360.120
sex differentiationGO:0007548810.117
regulation of catalytic activityGO:00507901850.114
hindgut morphogenesisGO:0007442580.112
response to radiationGO:00093141550.111
adult behaviorGO:00305341370.109
dna conformation changeGO:00711031050.107
tube morphogenesisGO:00352391910.107
response to bacteriumGO:00096171980.106
malpighian tubule morphogenesisGO:0007443440.103
defense response to other organismGO:00985422250.103
development of primary sexual characteristicsGO:0045137500.103
Mouse
small molecule metabolic processGO:00442813050.102
muscle structure developmentGO:00610612240.101
reproductive system developmentGO:0061458740.098
embryonic hindgut morphogenesisGO:0048619480.095
regulation of phosphate metabolic processGO:00192202100.091
cell fate specificationGO:0001708710.090
genital disc pattern formationGO:003522180.090
neural retina developmentGO:000340740.090
female gonad developmentGO:0008585120.090
negative regulation of cell communicationGO:00106482230.088
actin cytoskeleton organizationGO:00300362060.088
anatomical structure homeostasisGO:0060249970.087
establishment of localization in cellGO:00516494020.087
negative regulation of nucleic acid templated transcriptionGO:19035072400.085
actin filament based processGO:00300292200.085
phenol containing compound metabolic processGO:0018958570.084
circadian behaviorGO:0048512760.081
respiratory system developmentGO:00605412130.080
protein maturationGO:0051604710.079
eye morphogenesisGO:00485922600.078
immune responseGO:00069552460.078
protein localizationGO:00081042840.077
response to external biotic stimulusGO:00432072930.077
epithelial cell migrationGO:00106311480.076
response to alkaloidGO:0043279260.074
positive regulation of macromolecule metabolic processGO:00106044050.073
ovarian follicle cell developmentGO:00307072480.073
gastrulationGO:0007369700.072
autophagyGO:00069141080.072
negative regulation of signal transductionGO:00099682060.071
formation of primary germ layerGO:0001704240.070
cellular component assembly involved in morphogenesisGO:00109271510.069
cell recognitionGO:00080371020.068
compound eye photoreceptor developmentGO:0042051780.068
cellular response to oxygen containing compoundGO:1901701790.067
regulation of steroid metabolic processGO:001921820.066
regulation of tube architecture open tracheal systemGO:0035152680.066
negative regulation of macromolecule biosynthetic processGO:00105582700.066
negative regulation of cell deathGO:0060548810.065
actomyosin structure organizationGO:0031032560.064
response to abiotic stimulusGO:00096283410.063
organic substance catabolic processGO:19015753080.063
axon guidanceGO:00074112330.062
neuron recognitionGO:00080381010.061
sex determinationGO:0007530180.060
Mouse
female sex differentiationGO:0046660200.060
regulation of multicellular organismal developmentGO:20000264140.060
Mouse
regulation of response to stressGO:00801342000.059
positive regulation of cell migrationGO:003033520.059
single organism cellular localizationGO:19025801800.058
male gonad developmentGO:000858490.058
Mouse
regulation of cell deathGO:00109411730.058
growthGO:00400073590.057
phosphorylationGO:00163102940.056
morphogenesis of embryonic epitheliumGO:0016331940.056
striated muscle cell developmentGO:0055002500.055
defense response to bacteriumGO:00427421780.055
gonad developmentGO:0008406500.055
Mouse
secondary metabolic processGO:0019748750.055
myofibril assemblyGO:0030239360.055
positive regulation of molecular functionGO:00440931360.055
exocrine system developmentGO:00352721620.055
dorsal closureGO:0007391790.054
ribonucleotide metabolic processGO:00092591450.054
response to nitrogen compoundGO:1901698900.053
tissue migrationGO:00901301550.053
purine nucleoside metabolic processGO:00422781270.052
chromatin organizationGO:00063252070.052
developmental growth involved in morphogenesisGO:0060560650.051
ameboidal type cell migrationGO:00016671510.050
axis specificationGO:00097981670.050
tripartite regional subdivisionGO:00073511030.049
positive regulation of catalytic activityGO:00430851180.049
mesoderm formationGO:0001707210.047
positive regulation of signalingGO:00230562430.047
salivary gland morphogenesisGO:00074351450.046
stress activated mapk cascadeGO:0051403520.045
stem cell differentiationGO:00488631170.045
programmed cell deathGO:00125012570.045
regulation of intracellular signal transductionGO:19025312360.045
eye antennal disc developmentGO:0035214600.044
negative regulation of cell cycle processGO:00109481090.043
Mouse
embryonic axis specificationGO:00005781070.043
epithelial cell differentiationGO:00308553220.042
Mouse
purine ribonucleotide metabolic processGO:00091501450.042
regulation of cellular response to stressGO:0080135890.041
phenol containing compound biosynthetic processGO:004618960.040
negative regulation of signalingGO:00230572190.040
positive regulation of cell developmentGO:0010720610.039
retina development in camera type eyeGO:006004140.039
brain developmentGO:00074201200.039
skeletal muscle organ developmentGO:0060538480.039
chromosome organizationGO:00512763600.038
nucleotide metabolic processGO:00091171610.038
regulation of epithelial cell proliferationGO:005067840.037
regulation of programmed cell deathGO:00430671520.037
developmental maturationGO:00217001720.037
neuron fate commitmentGO:0048663500.037
dendrite morphogenesisGO:00488131990.037
renal system developmentGO:0072001720.037
regulation of organ morphogenesisGO:2000027780.036
histolysisGO:00075591020.036
intracellular transportGO:00469072280.036
limb morphogenesisGO:003510810.036
nucleoside phosphate metabolic processGO:00067531620.035
regulation of phosphorylationGO:00423251470.035
positive regulation of response to stimulusGO:00485843230.035
regulation of autophagyGO:0010506620.035
metal ion transportGO:0030001740.035
response to woundingGO:0009611940.035
post embryonic appendage morphogenesisGO:00351203850.035
regulation of nervous system developmentGO:00519602480.034
optic lobe placode developmentGO:0001748100.034
dorsal ventral pattern formation imaginal discGO:0007450510.034
response to biotic stimulusGO:00096072940.034
regulation of cellular protein metabolic processGO:00322682430.034
appendage developmentGO:00487364010.034
compound eye photoreceptor cell differentiationGO:00017511400.034
ribose phosphate metabolic processGO:00196931450.034
regulation of phosphorus metabolic processGO:00511742100.034
carbohydrate derivative biosynthetic processGO:1901137850.034
purine nucleotide metabolic processGO:00061631460.033
chemosensory behaviorGO:00076351060.033
telencephalon developmentGO:002153720.033
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.033
regulation of hydrolase activityGO:0051336970.032
aggressive behaviorGO:0002118630.032
imaginal disc derived wing morphogenesisGO:00074763370.032
ovarian follicle cell migrationGO:00072971210.032
regulation of compound eye retinal cell programmed cell deathGO:0046669180.032
single organism intracellular transportGO:19025822070.032
response to extracellular stimulusGO:00099911160.031
regulation of gene silencingGO:0060968630.031
macromolecular complex assemblyGO:00650032560.031
positive regulation of multicellular organismal processGO:00512401430.031
Mouse
apoptotic process involved in morphogenesisGO:006056130.030
protein modification processGO:00362114380.030
innate immune responseGO:00450871440.030
protein localization to organelleGO:0033365820.030
kidney epithelium developmentGO:007207330.030
border follicle cell migrationGO:00072981130.030
mesenchymal cell developmentGO:001403110.029
protein complex assemblyGO:00064612000.029
purine ribonucleoside monophosphate metabolic processGO:0009167500.029
columnar cuboidal epithelial cell developmentGO:00020662490.029
purine nucleoside monophosphate metabolic processGO:0009126500.029
negative regulation of nervous system developmentGO:0051961920.029
genital disc sexually dimorphic developmentGO:003526340.029
nucleobase containing small molecule metabolic processGO:00550861740.029
response to toxic substanceGO:0009636220.028
regulation of localizationGO:00328792750.028
mesenchymal cell differentiationGO:004876210.028
mitotic spindle organizationGO:00070522200.028
positive regulation of transportGO:0051050920.028
nuclear divisionGO:00002803320.028
Mouse
entrainment of circadian clockGO:0009649160.028
male gamete generationGO:00482322010.027
Mouse
cell deathGO:00082192790.027
response to glucoseGO:000974920.027
negative regulation of programmed cell deathGO:0043069720.027
muscle attachmentGO:0016203360.027
secretionGO:00469031090.027
positive regulation of developmental processGO:00510941430.027
Mouse
purine ribonucleoside metabolic processGO:00461281270.026
cell maturationGO:00484691440.026
cellular macromolecule localizationGO:00707272200.026
carbohydrate derivative metabolic processGO:19011352170.026
signal transduction by phosphorylationGO:00230141070.026
positive regulation of response to external stimulusGO:0032103440.026
agingGO:00075681430.026
actin filament organizationGO:00070151260.026
ribonucleoside monophosphate metabolic processGO:0009161510.026
regulation of anatomical structure sizeGO:00900661630.025
melanization defense responseGO:0035006450.025
proteolysisGO:00065081920.025
protein processingGO:0016485680.025
anterior posterior axis specification embryoGO:00085951030.025
gonadal mesoderm developmentGO:000750680.025
negative regulation of protein metabolic processGO:0051248850.025
positive regulation of apoptotic processGO:0043065470.025
photoreceptor cell fate commitmentGO:0046552410.025
visual perceptionGO:000760190.025
salivary gland developmentGO:00074311620.024
development of primary female sexual characteristicsGO:0046545120.024
eye antennal disc morphogenesisGO:0007455340.024
organelle fissionGO:00482853400.024
Mouse
wing and notum subfield formationGO:0035309130.024
regulation of embryonic cell shapeGO:0016476300.024
gland morphogenesisGO:00226121450.024
negative regulation of rna biosynthetic processGO:19026792400.024
negative regulation of apoptotic processGO:0043066630.024
catabolic processGO:00090564090.024
apoptotic process involved in developmentGO:1902742200.024
positive regulation of signal transductionGO:00099672230.024
negative regulation of neuron deathGO:1901215180.024
compound eye photoreceptor fate commitmentGO:0001752360.023
regulation of stress activated protein kinase signaling cascadeGO:0070302420.023
tissue homeostasisGO:0001894360.023
female genitalia developmentGO:003054060.023
kidney developmentGO:000182230.023
chemical homeostasisGO:0048878920.023
negative regulation of multicellular organismal processGO:00512411420.022
melanin metabolic processGO:0006582470.022
pigmentationGO:0043473750.022
positive regulation of phosphorus metabolic processGO:00105621390.022
positive regulation of cell deathGO:0010942690.022
positive regulation of compound eye retinal cell programmed cell deathGO:004667290.021
positive regulation of phosphate metabolic processGO:00459371390.021
hematopoietic or lymphoid organ developmentGO:0048534570.021
chitin based cuticle developmentGO:0040003490.021
organelle assemblyGO:00709251980.021
gland developmentGO:00487321910.020
open tracheal system developmentGO:00074242040.020
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.020
Mouse
developmental pigmentationGO:0048066680.020
cardiovascular system developmentGO:0072358820.020
immune system developmentGO:0002520570.020
regulation of developmental pigmentationGO:0048070240.020
cellular catabolic processGO:00442483720.020
mrna splicing via spliceosomeGO:0000398730.020
regulation of purine nucleotide metabolic processGO:1900542620.020
imaginal disc derived leg morphogenesisGO:0007480800.020
male genitalia developmentGO:0030539190.019
cuticle developmentGO:0042335860.019
embryo development ending in birth or egg hatchingGO:00097921520.019
cellular protein modification processGO:00064644380.019
response to light stimulusGO:00094161240.019
dorsal trunk growth open tracheal systemGO:003500170.019
regulation of locomotionGO:0040012420.019
salivary gland histolysisGO:0035070880.019
leg disc morphogenesisGO:0007478800.019
renal tubule morphogenesisGO:0061333440.019
determination of adult lifespanGO:00083401370.019
negative regulation of cell differentiationGO:00455961430.019
positive regulation of cell differentiationGO:0045597640.018
regulation of growthGO:00400082330.018
negative regulation of rna metabolic processGO:00512532510.018
organic acid metabolic processGO:00060821030.018
protein complex biogenesisGO:00702712010.018
genital disc developmentGO:0035215440.018
skin developmentGO:0043588650.018
regulation of embryonic developmentGO:0045995680.018
forebrain developmentGO:003090020.018
multicellular organismal agingGO:00102591400.018
cellular amino acid metabolic processGO:0006520610.018
axon choice point recognitionGO:0016198260.018
positive regulation of apoptotic signaling pathwayGO:200123540.018
regulation of apoptotic processGO:00429811300.018
neuromuscular junction developmentGO:00075281490.017
establishment of protein localizationGO:00451841630.017
gonad morphogenesisGO:003526270.017
establishment of blood brain barrierGO:0060856160.017
positive regulation of programmed cell deathGO:0043068620.017
nephron epithelium morphogenesisGO:007208830.017
reproductive structure developmentGO:0048608740.017
regulation of cellular localizationGO:00603411360.016
positive regulation of cell communicationGO:00106472500.016
kidney morphogenesisGO:006099330.016
organonitrogen compound biosynthetic processGO:19015661170.016
atp metabolic processGO:0046034490.016
dosage compensationGO:0007549160.016
mating behavior sex discriminationGO:004804770.016
nucleoside metabolic processGO:00091161270.016
cellular response to growth factor stimulusGO:0071363300.016
genital disc anterior posterior pattern formationGO:003522480.016
purine nucleoside monophosphate catabolic processGO:0009128380.016
response to ionizing radiationGO:0010212320.015
post embryonic hemopoiesisGO:0035166170.015
establishment or maintenance of cell polarityGO:00071631670.015
nucleoside monophosphate metabolic processGO:0009123520.015
nucleotide catabolic processGO:00091661090.015
chromatin silencingGO:0006342760.015
phagocytosisGO:00069092150.015
regulation of stem cell differentiationGO:2000736140.014
eye photoreceptor cell fate commitmentGO:0042706370.014
regulation of heart morphogenesisGO:200082630.014
purine ribonucleoside monophosphate catabolic processGO:0009169380.014
protein phosphorylationGO:00064681690.014
regulation of protein metabolic processGO:00512462560.014
regulation of anatomical structure morphogenesisGO:00226032420.014
response to ethanolGO:0045471590.014
nephron tubule morphogenesisGO:007207830.014
urogenital system developmentGO:0001655720.013
regulation of cell fate commitmentGO:0010453290.013
hindgut developmentGO:0061525580.013
regulation of transferase activityGO:0051338580.013
feeding behaviorGO:0007631500.013
regulation of cardiac cell fate specificationGO:200004380.013
immune effector processGO:0002252980.013
cellular homeostasisGO:0019725800.013
renal tubule developmentGO:0061326640.013
segment polarity determinationGO:0007367250.013
determination of genital disc primordiumGO:0035225100.013
nephron morphogenesisGO:007202830.013
hemocyte differentiationGO:0042386380.013
cell type specific apoptotic processGO:0097285380.013
epithelial cell developmentGO:00020642740.013
Mouse
regulation of response to external stimulusGO:00321011150.013
body morphogenesisGO:001017120.013
positive regulation of autophagyGO:0010508210.013
positive regulation of retinal cell programmed cell deathGO:004667090.013
regulation of cellular catabolic processGO:00313291570.013
genitalia morphogenesisGO:0035112160.012
rna splicingGO:0008380830.012
cardioblast cell fate commitmentGO:0042684140.012
regulation of immune system processGO:00026821760.012
neuron deathGO:0070997270.012
regulation of nucleotide metabolic processGO:0006140620.012
regulation of response to oxidative stressGO:190288240.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.012
Mouse
purine nucleoside triphosphate metabolic processGO:00091441190.012
ribonucleoside triphosphate metabolic processGO:00091991190.012
purine nucleotide catabolic processGO:00061951090.012
peptide metabolic processGO:0006518800.012
regulation of multi organism processGO:00439001310.011
sensory perception of mechanical stimulusGO:0050954720.011
muscle cell differentiationGO:00426921030.011
cellular response to nitrogen compoundGO:1901699510.011
mesodermal cell differentiationGO:004833370.011
response to heatGO:0009408630.011
negative regulation of epithelial cell proliferationGO:005068040.011
lymph gland developmentGO:0048542280.011
cellular response to extracellular stimulusGO:0031668640.011
regulation of cellular ketone metabolic processGO:001056530.011
macromolecule catabolic processGO:00090571610.011
gliogenesisGO:0042063800.011
bmp signaling pathwayGO:0030509270.011
positive regulation of cellular protein metabolic processGO:00322701180.011
heart inductionGO:000312930.011
cellular response to external stimulusGO:0071496660.011
negative regulation of cellular response to oxidative stressGO:190040810.011
positive regulation of phosphorylationGO:0042327870.011
purine ribonucleotide biosynthetic processGO:0009152280.011
filopodium assemblyGO:0046847330.010
cellular response to organic cyclic compoundGO:0071407320.010
embryonic heart tube developmentGO:0035050220.010
negative regulation of phosphorylationGO:0042326350.010
regulation of intracellular transportGO:0032386640.010
synaptic transmissionGO:00072682880.010
cellular amide metabolic processGO:0043603800.010
epithelial cell proliferationGO:0050673150.010
endocytosisGO:00068973100.010
regulation of jnk cascadeGO:0046328400.010

dsx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.126
nervous system diseaseDOID:86300.089
sensory system diseaseDOID:005015500.056
organ system cancerDOID:005068600.023
cancerDOID:16200.023
disease of cellular proliferationDOID:1456600.023
eye and adnexa diseaseDOID:149200.019
eye diseaseDOID:561400.013