IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG12299 (Dmel_CG12299)

CG12299 gene product from transcript CG12299-RA

(Aliases: Dmel\CG12299)

Entrez: 34483
FLYBASE: FBgn0032295
UniProtKB: Q9VKQ7

Process Predictions
Disease Predictions

CG12299 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
chromosome organization	GO:0051276	360	0.266
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.195
meiosis i	GO:0007127	59	0.139
negative regulation of cell cycle phase transition	GO:1901988	103	0.123
phosphorylation	GO:0016310	294	0.120
organelle fission	GO:0048285	340	0.107
pigment metabolic process	GO:0042440	84	0.106
embryo development ending in birth or egg hatching	GO:0009792	152	0.105
protein modification process	GO:0036211	438	0.095
regulation of phosphorus metabolic process	GO:0051174	210	0.091
mitotic spindle organization	GO:0007052	220	0.089
lateral inhibition	GO:0046331	206	0.089
negative regulation of cellular metabolic process	GO:0031324	382	0.081
nuclear division	GO:0000280	332	0.078
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.077
regulation of phosphate metabolic process	GO:0019220	210	0.065
regulation of cellular protein metabolic process	GO:0032268	243	0.064
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.064
mitotic dna damage checkpoint	GO:0044773	74	0.062
regulation of protein metabolic process	GO:0051246	256	0.061
sister chromatid segregation	GO:0000819	92	0.060
cellular protein modification process	GO:0006464	438	0.059
meiotic cell cycle process	GO:1903046	132	0.059
dendrite morphogenesis	GO:0048813	199	0.058
chromatin organization	GO:0006325	207	0.056
regulation of multicellular organismal development	GO:2000026	414	0.053
histone modification	GO:0016570	106	0.052
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.051
positive regulation of macromolecule metabolic process	GO:0010604	405	0.047
response to other organism	GO:0051707	293	0.046
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.045
chromatin modification	GO:0016568	147	0.045
determination of adult lifespan	GO:0008340	137	0.045
negative regulation of signaling	GO:0023057	219	0.044
embryonic development via the syncytial blastoderm	GO:0001700	148	0.043
spermatid differentiation	GO:0048515	114	0.043
proteolysis	GO:0006508	192	0.042
response to abiotic stimulus	GO:0009628	341	0.041
regulation of cell cycle	GO:0051726	291	0.041
spindle organization	GO:0007051	253	0.041
regulation of cell cycle phase transition	GO:1901987	130	0.040
negative regulation of erk1 and erk2 cascade	GO:0070373	3	0.039
meiotic cell cycle	GO:0051321	171	0.038
establishment or maintenance of cell polarity	GO:0007163	167	0.038
regulation of phosphorylation	GO:0042325	147	0.038
macromolecular complex assembly	GO:0065003	256	0.038	Yeast
chromosome condensation	GO:0030261	41	0.037
response to external biotic stimulus	GO:0043207	293	0.037
establishment of localization in cell	GO:0051649	402	0.037
regulation of cell differentiation	GO:0045595	302	0.035
positive regulation of cellular biosynthetic process	GO:0031328	316	0.035
signal transduction by phosphorylation	GO:0023014	107	0.034
male gamete generation	GO:0048232	201	0.033
negative regulation of biosynthetic process	GO:0009890	277	0.033
cell cycle checkpoint	GO:0000075	95	0.033
protein k48 linked ubiquitination	GO:0070936	3	0.032
regulation of gene expression epigenetic	GO:0040029	128	0.032
positive regulation of phosphorylation	GO:0042327	87	0.032
g2 dna damage checkpoint	GO:0031572	69	0.031
defense response to other organism	GO:0098542	225	0.031
meiotic nuclear division	GO:0007126	151	0.031
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.030
positive regulation of gene expression	GO:0010628	290	0.030
mitotic cell cycle checkpoint	GO:0007093	88	0.029
aging	GO:0007568	143	0.029
peptidyl amino acid modification	GO:0018193	105	0.028
protein phosphorylation	GO:0006468	169	0.028
dendrite development	GO:0016358	204	0.028
regulation of transport	GO:0051049	181	0.028
positive regulation of phosphorus metabolic process	GO:0010562	139	0.027
mitotic nuclear division	GO:0007067	213	0.027
catabolic process	GO:0009056	409	0.027
mapk cascade	GO:0000165	107	0.027
vesicle mediated transport	GO:0016192	381	0.027
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.027
regulation of mitotic cell cycle	GO:0007346	190	0.026
regulation of nervous system development	GO:0051960	248	0.026
regulation of cellular amino acid metabolic process	GO:0006521	0	0.025
mitotic sister chromatid segregation	GO:0000070	87	0.025
single organism behavior	GO:0044708	391	0.024
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.024
imaginal disc derived wing morphogenesis	GO:0007476	337	0.024
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.024
mitotic cell cycle phase transition	GO:0044772	138	0.024
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.024
nuclear import	GO:0051170	51	0.024
single organism intracellular transport	GO:1902582	207	0.024
regulation of catalytic activity	GO:0050790	185	0.023
regulation of erk1 and erk2 cascade	GO:0070372	39	0.023
positive regulation of catabolic process	GO:0009896	105	0.023
carboxylic acid metabolic process	GO:0019752	92	0.023
transcription from rna polymerase ii promoter	GO:0006366	368	0.023
response to biotic stimulus	GO:0009607	294	0.022
regulation of mapk cascade	GO:0043408	92	0.022
regulation of molecular function	GO:0065009	217	0.021
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.021
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.021
cellular amino acid metabolic process	GO:0006520	61	0.021
posttranscriptional regulation of gene expression	GO:0010608	145	0.021
dephosphorylation	GO:0016311	51	0.021
organic substance catabolic process	GO:1901575	308	0.020
negative regulation of intracellular signal transduction	GO:1902532	57	0.020
death	GO:0016265	284	0.020
oxoacid metabolic process	GO:0043436	103	0.020
mitochondrial membrane organization	GO:0007006	3	0.020
negative regulation of phosphate metabolic process	GO:0045936	45	0.020
regulation of ras protein signal transduction	GO:0046578	93	0.020
positive regulation of protein metabolic process	GO:0051247	128	0.019
protein localization to organelle	GO:0033365	82	0.019
positive regulation of catalytic activity	GO:0043085	118	0.019
gland development	GO:0048732	191	0.019
regulation of localization	GO:0032879	275	0.019
post embryonic appendage morphogenesis	GO:0035120	385	0.019
neurological system process	GO:0050877	358	0.018
body morphogenesis	GO:0010171	2	0.018
intracellular transport	GO:0046907	228	0.018
negative regulation of mitotic cell cycle	GO:0045930	109	0.018
positive regulation of rna biosynthetic process	GO:1902680	266	0.018
cellular macromolecule catabolic process	GO:0044265	136	0.018
negative regulation of protein metabolic process	GO:0051248	85	0.018
regulation of cellular amine metabolic process	GO:0033238	3	0.018
cellular ketone metabolic process	GO:0042180	24	0.018
regulation of cellular ketone metabolic process	GO:0010565	3	0.018
cellular amine metabolic process	GO:0044106	12	0.018
dna integrity checkpoint	GO:0031570	81	0.018
positive regulation of signaling	GO:0023056	243	0.017
cell cycle phase transition	GO:0044770	140	0.017
regulation of embryonic development	GO:0045995	68	0.017
mitotic dna integrity checkpoint	GO:0044774	75	0.017
covalent chromatin modification	GO:0016569	106	0.017
organelle assembly	GO:0070925	198	0.017
chromosome segregation	GO:0007059	157	0.017
positive regulation of phosphate metabolic process	GO:0045937	139	0.017
regulation of anatomical structure morphogenesis	GO:0022603	242	0.017
cellular response to dna damage stimulus	GO:0006974	223	0.017
cell proliferation	GO:0008283	299	0.017
endocytosis	GO:0006897	310	0.016
larval development	GO:0002164	104	0.016
erk1 and erk2 cascade	GO:0070371	39	0.016
negative regulation of rna metabolic process	GO:0051253	251	0.016
positive regulation of neuron projection regeneration	GO:0070572	3	0.016
protein complex biogenesis	GO:0070271	201	0.016
cellular catabolic process	GO:0044248	372	0.016
establishment of protein localization	GO:0045184	163	0.016
negative regulation of phosphorylation	GO:0042326	35	0.016
positive regulation of mapk cascade	GO:0043410	63	0.016
organonitrogen compound metabolic process	GO:1901564	318	0.015
cellular macromolecular complex assembly	GO:0034622	153	0.015	Yeast
regulation of cellular localization	GO:0060341	136	0.015
jnk cascade	GO:0007254	50	0.015
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.015
chromosome organization involved in meiosis	GO:0070192	10	0.015
epithelial cell development	GO:0002064	274	0.015
positive regulation of cellular protein metabolic process	GO:0032270	118	0.015
negative regulation of transcription factor import into nucleus	GO:0042992	4	0.015
response to wounding	GO:0009611	94	0.015
regulation of chromatin modification	GO:1903308	28	0.014
regulation of cellular catabolic process	GO:0031329	157	0.014
multicellular organismal aging	GO:0010259	140	0.014
protein catabolic process	GO:0030163	101	0.014
negative regulation of gene expression	GO:0010629	387	0.014
developmental growth	GO:0048589	280	0.014
proteasomal protein catabolic process	GO:0010498	59	0.014
stem cell development	GO:0048864	79	0.014
single organism biosynthetic process	GO:0044711	206	0.014
regulation of cell development	GO:0060284	215	0.014
protein transport	GO:0015031	155	0.014
regulation of proteolysis	GO:0030162	87	0.013
regulation of hydrolase activity	GO:0051336	97	0.013
salivary gland morphogenesis	GO:0007435	145	0.013
neural precursor cell proliferation	GO:0061351	75	0.013
response to organic substance	GO:0010033	284	0.013
regulation of catabolic process	GO:0009894	170	0.013
gene silencing	GO:0016458	138	0.013
neuroblast proliferation	GO:0007405	74	0.013
mitotic g2 dna damage checkpoint	GO:0007095	69	0.013
cell death	GO:0008219	279	0.013
learning or memory	GO:0007611	141	0.013
dna damage checkpoint	GO:0000077	78	0.013
positive regulation of transcription dna templated	GO:0045893	266	0.013
cellular macromolecule localization	GO:0070727	220	0.013
response to endogenous stimulus	GO:0009719	119	0.013
organic acid metabolic process	GO:0006082	103	0.012
positive regulation of response to stimulus	GO:0048584	323	0.012
formation of a compartment boundary	GO:0060288	4	0.012
phosphatidylethanolamine metabolic process	GO:0046337	1	0.012
protein complex assembly	GO:0006461	200	0.012
amine metabolic process	GO:0009308	12	0.012
negative regulation of cell communication	GO:0010648	223	0.012
protein import	GO:0017038	55	0.012
negative regulation of signal transduction	GO:0009968	206	0.012
negative regulation of response to stimulus	GO:0048585	258	0.012
positive regulation of chromatin silencing at telomere	GO:0031940	2	0.012
regulation of chromosome organization	GO:0033044	64	0.012
single organism catabolic process	GO:0044712	228	0.012
antimicrobial humoral response	GO:0019730	99	0.012
cell division	GO:0051301	248	0.012
somatic stem cell division	GO:0048103	37	0.011
positive regulation of intracellular signal transduction	GO:1902533	116	0.011
negative regulation of cellular biosynthetic process	GO:0031327	277	0.011
regulation of growth	GO:0040008	233	0.011
response to radiation	GO:0009314	155	0.011
apoptotic process	GO:0006915	159	0.011
phagocytosis	GO:0006909	215	0.011
regulation of cellular response to stress	GO:0080135	89	0.011
appendage development	GO:0048736	401	0.011
sister chromatid cohesion	GO:0007062	18	0.011
positive regulation of biosynthetic process	GO:0009891	316	0.011
positive regulation of cellular catabolic process	GO:0031331	95	0.011
regulation of protein phosphorylation	GO:0001932	64	0.011
positive regulation of cell communication	GO:0010647	250	0.011
membrane organization	GO:0061024	112	0.011
modification dependent protein catabolic process	GO:0019941	78	0.011
endomembrane system organization	GO:0010256	119	0.010
multi organism behavior	GO:0051705	175	0.010
reproductive system development	GO:0061458	74	0.010
negative regulation of wnt signaling pathway	GO:0030178	28	0.010
positive regulation of organelle organization	GO:0010638	65	0.010
cellular response to organic substance	GO:0071310	132	0.010
cell adhesion	GO:0007155	136	0.010

CG12299 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.141
nervous system disease	DOID:863	0.023
disease of cellular proliferation	DOID:14566	0.015

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