Drosophila melanogaster

71 known processes

Su(var)2-HP2 (Dmel_CG12864)

CG12864 gene product from transcript CG12864-RB

(Aliases: Dmel\CG12864,SU(VAR)2-HP2,CG12864,HP2)

Su(var)2-HP2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromosome organizationGO:00512763600.993
chromatin silencingGO:0006342760.988
negative regulation of gene expression epigeneticGO:0045814770.951
chromatin organizationGO:00063252070.925
regulation of gene expression epigeneticGO:00400291280.893
gene silencingGO:00164581380.890
heterochromatin organizationGO:0070828250.863
heterochromatin organization involved in chromatin silencingGO:007086890.855
negative regulation of gene expressionGO:00106293870.680
chromatin modificationGO:00165681470.680
negative regulation of nucleobase containing compound metabolic processGO:00459342610.651
negative regulation of cellular biosynthetic processGO:00313272770.647
dna metabolic processGO:00062592270.622
negative regulation of biosynthetic processGO:00098902770.590
negative regulation of rna biosynthetic processGO:19026792400.571
cellular response to dna damage stimulusGO:00069742230.509
negative regulation of transcription dna templatedGO:00458922370.449
negative regulation of cellular metabolic processGO:00313243820.436
meiotic cell cycleGO:00513211710.433
organelle fissionGO:00482853400.411
cell cycle checkpointGO:0000075950.392
chromatin assemblyGO:0031497480.389
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.375
telomere maintenanceGO:0000723210.359
regulation of organelle organizationGO:00330431960.330
regulation of chromosome organizationGO:0033044640.324
positive regulation of macromolecule biosynthetic processGO:00105572830.314
dna packagingGO:0006323910.310
negative regulation of nitrogen compound metabolic processGO:00511722650.301
negative regulation of macromolecule biosynthetic processGO:00105582700.298
dna replicationGO:0006260480.297
sister chromatid segregationGO:0000819920.295
dna conformation changeGO:00711031050.287
dna damage checkpointGO:0000077780.283
chromosome segregationGO:00070591570.280
covalent chromatin modificationGO:00165691060.277
negative regulation of nucleic acid templated transcriptionGO:19035072400.253
chromatin assembly or disassemblyGO:0006333520.252
nuclear divisionGO:00002803320.237
nucleosome mobilizationGO:004276690.226
negative regulation of rna metabolic processGO:00512532510.223
mitotic dna damage checkpointGO:0044773740.221
peptidyl lysine methylationGO:0018022160.204
dna repairGO:0006281540.203
nucleosome organizationGO:0034728590.202
catabolic processGO:00090564090.172
cellular protein modification processGO:00064644380.166
centrosome organizationGO:00512971630.155
positive regulation of gene expressionGO:00106282900.142
small molecule metabolic processGO:00442813050.139
regulation of chromatin silencingGO:0031935360.136
histone modificationGO:00165701060.135
meiotic cell cycle processGO:19030461320.134
positive regulation of rna metabolic processGO:00512542710.128
meiotic chromosome segregationGO:0045132590.125
cellular catabolic processGO:00442483720.121
small rna loading onto riscGO:007092260.119
dosage compensationGO:0007549160.117
aromatic compound catabolic processGO:00194391660.116
organic substance catabolic processGO:19015753080.114
g2 dna damage checkpointGO:0031572690.107
nucleobase containing compound catabolic processGO:00346551650.103
posttranscriptional gene silencing by rnaGO:0035194450.100
chromatin remodelingGO:0006338720.099
organophosphate metabolic processGO:00196371950.098
microtubule organizing center organizationGO:00310231680.098
posttranscriptional gene silencingGO:0016441460.096
regulation of transcription by chromatin organizationGO:003440130.094
double strand break repairGO:0006302260.090
neuron projection guidanceGO:00974852410.090
regulation of mitotic cell cycleGO:00073461900.089
protein modification processGO:00362114380.085
regulation of dna metabolic processGO:0051052340.085
purine ribonucleoside metabolic processGO:00461281270.082
negative regulation of mitotic cell cycleGO:00459301090.082
regulation of cellular amine metabolic processGO:003323830.082
nucleoside triphosphate catabolic processGO:00091431080.080
meiotic nuclear divisionGO:00071261510.080
histone h4 k20 methylationGO:003477040.079
purine nucleotide catabolic processGO:00061951090.077
mitotic g2 dna damage checkpointGO:0007095690.076
positive regulation of nitrogen compound metabolic processGO:00511733540.075
mitotic cell cycle phase transitionGO:00447721380.073
purine nucleoside metabolic processGO:00422781270.073
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.073
negative regulation of cell cycleGO:00457861160.072
single organism catabolic processGO:00447122280.071
sister chromatid cohesionGO:0007062180.070
regulation of cell cycle processGO:00105641810.069
organonitrogen compound metabolic processGO:19015643180.068
mitotic g2 m transition checkpointGO:0044818700.068
purine ribonucleotide catabolic processGO:00091541090.066
regionalizationGO:00030024160.065
positive regulation of cellular catabolic processGO:0031331950.065
positive regulation of nucleobase containing compound metabolic processGO:00459353320.064
cellular macromolecule catabolic processGO:00442651360.063
nucleoside catabolic processGO:00091641120.063
embryo development ending in birth or egg hatchingGO:00097921520.063
telomere organizationGO:0032200210.063
cellular ketone metabolic processGO:0042180240.063
regulation of transcription from rna polymerase ii promoterGO:00063573780.063
purine ribonucleoside catabolic processGO:00461301120.062
ribonucleoside catabolic processGO:00424541120.062
telomere cappingGO:0016233110.061
transcription from rna polymerase ii promoterGO:00063663680.061
regulation of cell cycleGO:00517262910.059
nucleoside triphosphate metabolic processGO:00091411200.059
ribonucleoside monophosphate catabolic processGO:0009158390.059
purine nucleoside catabolic processGO:00061521120.058
centrosome duplicationGO:00512981210.058
negative regulation of mitotic cell cycle phase transitionGO:19019911030.057
axonogenesisGO:00074092900.057
ribose phosphate metabolic processGO:00196931450.057
signal transduction in response to dna damageGO:004277030.054
cell cycle phase transitionGO:00447701400.053
dna methylationGO:000630640.052
mitotic sister chromatid segregationGO:0000070870.052
gene silencing by rnaGO:0031047570.052
protein dna complex subunit organizationGO:0071824860.052
purine ribonucleoside monophosphate catabolic processGO:0009169380.052
mitotic cell cycle checkpointGO:0007093880.051
heterocycle catabolic processGO:00467001660.051
positive regulation of transcription dna templatedGO:00458932660.051
regulation of mitotic cell cycle phase transitionGO:19019901300.050
positive regulation of rna biosynthetic processGO:19026802660.050
modification dependent macromolecule catabolic processGO:0043632790.049
peptidyl lysine trimethylationGO:001802360.049
production of sirna involved in rna interferenceGO:0030422110.049
methylationGO:0032259470.049
dna integrity checkpointGO:0031570810.048
glycosyl compound metabolic processGO:19016571270.048
purine ribonucleoside triphosphate catabolic processGO:00092071080.048
regulation of catabolic processGO:00098941700.048
negative regulation of organelle organizationGO:0010639560.047
regulation of cellular catabolic processGO:00313291570.045
cellular nitrogen compound catabolic processGO:00442701650.045
mitotic cell cycle embryonicGO:0045448380.044
negative regulation of cell cycle phase transitionGO:19019881030.044
response to organic cyclic compoundGO:0014070890.044
macromolecular complex assemblyGO:00650032560.043
nucleotide catabolic processGO:00091661090.043
taxisGO:00423303040.042
male courtship behavior veined wing generated song productionGO:0045433200.042
organophosphate catabolic processGO:00464341120.041
dsrna fragmentationGO:0031050150.041
regulation of cellular ketone metabolic processGO:001056530.041
histone lysine methylationGO:0034968320.041
organic cyclic compound catabolic processGO:19013611680.040
purine nucleoside triphosphate metabolic processGO:00091441190.039
production of small rna involved in gene silencing by rnaGO:0070918150.038
cellular response to ketoneGO:1901655170.037
proteolysis involved in cellular protein catabolic processGO:0051603830.036
centrosome cycleGO:00070981370.036
regulation of cellular protein metabolic processGO:00322682430.036
single organism biosynthetic processGO:00447112060.035
carbohydrate derivative catabolic processGO:19011361180.035
positive regulation of macromolecule metabolic processGO:00106044050.035
ribonucleotide catabolic processGO:00092611090.035
atp dependent chromatin remodelingGO:0043044220.035
cell cycle dna replicationGO:0044786230.034
ubiquitin dependent protein catabolic processGO:0006511780.033
ribonucleotide metabolic processGO:00092591450.033
rna interferenceGO:0016246270.032
protein catabolic processGO:00301631010.032
localization of cellGO:00516742570.032
nucleosome positioningGO:001658430.031
ribonucleoside metabolic processGO:00091191270.030
purine containing compound catabolic processGO:00725231120.030
appendage morphogenesisGO:00351073970.030
regulation of cellular amino acid metabolic processGO:000652100.030
chromatin maintenanceGO:007082720.030
positive regulation of catabolic processGO:00098961050.030
dna methylation or demethylationGO:004472840.030
cellular protein catabolic processGO:0044257830.029
positive regulation of cellular protein metabolic processGO:00322701180.029
dendrite morphogenesisGO:00488131990.029
dorsal ventral pattern formationGO:00099531330.029
purine containing compound metabolic processGO:00725211550.029
protein complex biogenesisGO:00702712010.029
purine ribonucleotide metabolic processGO:00091501450.029
regulation of proteasomal protein catabolic processGO:0061136390.029
ribonucleoside triphosphate metabolic processGO:00091991190.028
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.028
nucleoside phosphate catabolic processGO:19012921100.028
positive regulation of biosynthetic processGO:00098913160.028
positive regulation of organelle organizationGO:0010638650.028
regulation of chromatin organizationGO:1902275320.027
purine nucleoside monophosphate metabolic processGO:0009126500.027
purine ribonucleoside triphosphate metabolic processGO:00092051190.027
chemotaxisGO:00069352490.027
negative regulation of cell cycle processGO:00109481090.027
posttranscriptional regulation of gene expressionGO:00106081450.027
nucleotide metabolic processGO:00091171610.027
purine nucleotide metabolic processGO:00061631460.027
histone methylationGO:0016571400.026
regulation of cellular protein catabolic processGO:1903362440.026
axon guidanceGO:00074112330.026
modification dependent protein catabolic processGO:0019941780.026
positive regulation of nucleic acid templated transcriptionGO:19035082660.026
peptidyl lysine modificationGO:0018205570.026
homeostatic processGO:00425921990.026
regulation of localizationGO:00328792750.026
dendrite developmentGO:00163582040.026
glycosyl compound catabolic processGO:19016581120.026
appendage developmentGO:00487364010.026
chromosome separationGO:0051304420.026
ribonucleoside triphosphate catabolic processGO:00092031080.025
olfactory learningGO:0008355560.025
neurological system processGO:00508773580.025
nucleobase containing small molecule metabolic processGO:00550861740.025
wing disc morphogenesisGO:00074723440.024
purine ribonucleoside monophosphate metabolic processGO:0009167500.024
regulation of response to dna damage stimulusGO:2001020230.024
response to sterolGO:0036314340.024
tissue morphogenesisGO:00487292970.024
anatomical structure homeostasisGO:0060249970.024
axon developmentGO:00615642970.024
nucleoside monophosphate metabolic processGO:0009123520.024
regulation of gene silencingGO:0060968630.024
reproductive structure developmentGO:0048608740.024
embryonic development via the syncytial blastodermGO:00017001480.023
cellular response to dsrnaGO:0071359150.023
cellular response to chemical stimulusGO:00708871990.023
mitotic chromosome condensationGO:0007076220.023
organonitrogen compound catabolic processGO:19015651280.023
histone acetylationGO:0016573380.022
gland developmentGO:00487321910.022
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.022
developmental growthGO:00485892800.022
regulation of neuron differentiationGO:00456641030.022
negative regulation of cellular component organizationGO:00511291080.022
protein modification by small protein conjugation or removalGO:00706471060.022
imaginal disc derived appendage developmentGO:00487373990.022
dosage compensation by hyperactivation of x chromosomeGO:000904770.021
positive regulation of cellular amine metabolic processGO:003324000.021
reproductive system developmentGO:0061458740.021
cellular macromolecular complex assemblyGO:00346221530.021
forebrain developmentGO:003090020.020
regulation of chromatin modificationGO:1903308280.020
regulation of nuclear divisionGO:0051783580.020
nucleoside metabolic processGO:00091161270.020
peptidyl amino acid modificationGO:00181931050.020
nucleoside phosphate metabolic processGO:00067531620.020
single organism intracellular transportGO:19025822070.020
negative regulation of cell divisionGO:0051782170.019
dna dependent dna replicationGO:0006261170.019
regulation of protein metabolic processGO:00512462560.019
peptidyl lysine dimethylationGO:001802730.019
response to organic substanceGO:00100332840.019
atp metabolic processGO:0046034490.019
positive regulation of cellular biosynthetic processGO:00313283160.019
gliogenesisGO:0042063800.019
protein complex assemblyGO:00064612000.019
purine nucleoside triphosphate catabolic processGO:00091461080.019
histone h3 k4 methylationGO:0051568160.018
cell deathGO:00082192790.018
positive regulation of apoptotic signaling pathwayGO:200123540.018
negative regulation of signal transductionGO:00099682060.018
response to ionizing radiationGO:0010212320.018
ribonucleoside monophosphate metabolic processGO:0009161510.018
protein alkylationGO:0008213430.018
regulation of cellular response to stressGO:0080135890.018
cellular response to organic cyclic compoundGO:0071407320.017
regulation of mitotic sister chromatid segregationGO:0033047280.017
intracellular transportGO:00469072280.017
protein modification by small protein conjugationGO:0032446790.017
negative regulation of chromosome organizationGO:2001251190.017
mitotic nuclear divisionGO:00070672130.017
regulation of catalytic activityGO:00507901850.016
negative regulation of cell differentiationGO:00455961430.016
response to dsrnaGO:0043331150.016
nuclear body organizationGO:003057560.016
regulation of neurogenesisGO:00507671580.016
response to nitrogen compoundGO:1901698900.016
regulation of protein catabolic processGO:0042176550.015
camera type eye developmentGO:004301040.015
carbohydrate derivative metabolic processGO:19011352170.015
intracellular steroid hormone receptor signaling pathwayGO:0030518120.015
limb morphogenesisGO:003510810.015
cellular response to oxygen levelsGO:0071453300.015
body morphogenesisGO:001017120.015
male meiosis chromosome segregationGO:0007060100.015
imaginal disc derived wing morphogenesisGO:00074763370.015
histone exchangeGO:0043486210.014
cell agingGO:000756920.014
targeting of mrna for destruction involved in rna interferenceGO:003042340.014
mitotic dna integrity checkpointGO:0044774750.014
histone h3 k27 methylationGO:007073460.014
regulation of photoreceptor cell differentiationGO:0046532340.014
organic substance transportGO:00717022570.014
carboxylic acid metabolic processGO:0019752920.014
mitotic sister chromatid separationGO:0051306300.014
protein acetylationGO:0006473390.014
single organism cellular localizationGO:19025801800.013
innate immune responseGO:00450871440.013
macromolecule methylationGO:0043414450.013
regulation of wnt signaling pathwayGO:0030111680.013
sex differentiationGO:0007548810.013
proteasomal protein catabolic processGO:0010498590.013
wnt signaling pathwayGO:0016055980.013
protein dna complex assemblyGO:0065004630.013
response to ketoneGO:1901654340.013
regulation of cell differentiationGO:00455953020.013
regulation of behaviorGO:0050795750.012
regulation of cell cycle phase transitionGO:19019871300.012
positive regulation of neurogenesisGO:0050769410.012
nucleoside monophosphate catabolic processGO:0009125390.012
oxoacid metabolic processGO:00434361030.012
response to bacteriumGO:00096171980.012
positive regulation of cellular component organizationGO:00511301560.012
growthGO:00400073590.012
regulation of defense response to virus by hostGO:0050691100.012
response to ecdysoneGO:0035075340.012
proteolysisGO:00065081920.011
atp catabolic processGO:0006200380.011
embryonic hemopoiesisGO:0035162260.011
positive regulation of chromatin silencingGO:0031937160.011
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.011
wound healingGO:0042060750.011
establishment of localization in cellGO:00516494020.011
response to oxygen containing compoundGO:19017002000.011
regulation of gtp catabolic processGO:0033124440.011
replication fork processingGO:003129700.011
karyosome formationGO:0030717220.011
apoptotic signaling pathwayGO:0097190270.011
dna modificationGO:000630450.011
regulation of dna replicationGO:0006275130.011
negative regulation of neurogenesisGO:0050768530.010
post embryonic appendage morphogenesisGO:00351203850.010
development of primary sexual characteristicsGO:0045137500.010
positive regulation of cell developmentGO:0010720610.010
positive regulation of phosphate metabolic processGO:00459371390.010
cellular component maintenanceGO:0043954230.010
negative regulation of multicellular organismal processGO:00512411420.010
positive regulation of nucleoside metabolic processGO:0045979470.010

Su(var)2-HP2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.038
organ system cancerDOID:005068600.038
cancerDOID:16200.038
disease of anatomical entityDOID:700.017