IMP: Integrative Multi-species Prediction

Drosophila melanogaster

21 known processes

RpS13 (Dmel_CG13389)

Ribosomal protein S13

(Aliases: S13,Dmel\CG13389,CG13389,M(2)32,Rp17,M(2)32A,M(2)29B,l(2)k09614)

Entrez: 34149
FLYBASE: FBgn0010265
UniProtKB: Q03334
UniProtKB: X2J950

Process Predictions
Disease Predictions

RpS13 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
spindle elongation	GO:0051231	83	0.964
mitotic spindle elongation	GO:0000022	81	0.958
mitotic spindle organization	GO:0007052	220	0.924
centrosome duplication	GO:0051298	121	0.905
rrna processing	GO:0006364	3	0.871	Yeast
centrosome cycle	GO:0007098	137	0.839
embryo development ending in birth or egg hatching	GO:0009792	152	0.780	Worm
spindle organization	GO:0007051	253	0.638
larval development	GO:0002164	104	0.601	Worm
negative regulation of gene expression	GO:0010629	387	0.401	Human
translation	GO:0006412	69	0.367
regulation of growth	GO:0040008	233	0.308
microtubule organizing center organization	GO:0031023	168	0.291
cytoplasmic translation	GO:0002181	0	0.253
apoptotic process	GO:0006915	159	0.237
growth	GO:0040007	359	0.218
regulation of protein metabolic process	GO:0051246	256	0.195
posttranscriptional regulation of gene expression	GO:0010608	145	0.195
cell death	GO:0008219	279	0.189
rna processing	GO:0006396	147	0.178	Human Yeast
centrosome organization	GO:0051297	163	0.177
dna metabolic process	GO:0006259	227	0.173
negative regulation of response to stimulus	GO:0048585	258	0.145
death	GO:0016265	284	0.145
ncrna metabolic process	GO:0034660	43	0.134	Yeast
regulation of developmental growth	GO:0048638	174	0.126
body morphogenesis	GO:0010171	2	0.121
cellular protein modification process	GO:0006464	438	0.118
regulation of cellular protein metabolic process	GO:0032268	243	0.106
phosphorylation	GO:0016310	294	0.104
ribosomal large subunit biogenesis	GO:0042273	1	0.095
homeostatic process	GO:0042592	199	0.094
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.092
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.091
positive regulation of protein metabolic process	GO:0051247	128	0.083
nuclear export	GO:0051168	24	0.081
ribonucleoprotein complex biogenesis	GO:0022613	31	0.080	Yeast
positive regulation of macromolecule metabolic process	GO:0010604	405	0.080
molting cycle	GO:0042303	56	0.079
protein phosphorylation	GO:0006468	169	0.076
determination of adult lifespan	GO:0008340	137	0.076
developmental growth	GO:0048589	280	0.073
positive regulation of response to stimulus	GO:0048584	323	0.073
protein modification process	GO:0036211	438	0.071
programmed cell death	GO:0012501	257	0.068
rna localization	GO:0006403	115	0.066
regulation of multicellular organism growth	GO:0040014	40	0.065
regulation of translation	GO:0006417	56	0.064
response to monosaccharide	GO:0034284	4	0.064
positive regulation of gene expression	GO:0010628	290	0.060
organonitrogen compound metabolic process	GO:1901564	318	0.058
establishment of localization in cell	GO:0051649	402	0.057
positive regulation of cell communication	GO:0010647	250	0.052
negative regulation of signaling	GO:0023057	219	0.050
ribosome biogenesis	GO:0042254	8	0.048	Yeast
multicellular organismal aging	GO:0010259	140	0.047
regulation of cellular catabolic process	GO:0031329	157	0.046
positive regulation of biosynthetic process	GO:0009891	316	0.045
regulation of cellular component biogenesis	GO:0044087	201	0.045
positive regulation of cellular protein metabolic process	GO:0032270	118	0.045
intracellular transport	GO:0046907	228	0.043
negative regulation of signal transduction	GO:0009968	206	0.043
positive regulation of developmental growth	GO:0048639	62	0.042
positive regulation of cellular biosynthetic process	GO:0031328	316	0.042
regulation of multicellular organismal development	GO:2000026	414	0.042
neurological system process	GO:0050877	358	0.041
positive regulation of phosphate metabolic process	GO:0045937	139	0.040
regulation of molecular function	GO:0065009	217	0.040
mitotic cell cycle checkpoint	GO:0007093	88	0.040
positive regulation of phosphorylation	GO:0042327	87	0.039
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.038
cell growth	GO:0016049	108	0.037
organelle fission	GO:0048285	340	0.036
regulation of wnt signaling pathway	GO:0030111	68	0.036
aging	GO:0007568	143	0.034
heterocycle catabolic process	GO:0046700	166	0.033
regulation of apoptotic process	GO:0042981	130	0.033
amine metabolic process	GO:0009308	12	0.033
positive regulation of signaling	GO:0023056	243	0.032
regulation of response to stress	GO:0080134	200	0.032
regulation of intracellular signal transduction	GO:1902531	236	0.032
protein processing	GO:0016485	68	0.031
cytoplasmic transport	GO:0016482	130	0.031
macromolecule catabolic process	GO:0009057	161	0.031
positive regulation of hydrolase activity	GO:0051345	78	0.031
reproductive structure development	GO:0048608	74	0.031	Worm
regulation of phosphate metabolic process	GO:0019220	210	0.031
regulation of phosphorus metabolic process	GO:0051174	210	0.030
positive regulation of developmental process	GO:0051094	143	0.030
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.029	Human
ncrna processing	GO:0034470	30	0.029	Yeast
digestive system development	GO:0055123	149	0.029
regulation of peptidase activity	GO:0052547	39	0.029
translational elongation	GO:0006414	4	0.028
regulation of programmed cell death	GO:0043067	152	0.028
intracellular signal transduction	GO:0035556	300	0.028
multicellular organism growth	GO:0035264	46	0.027
circulatory system development	GO:0072359	82	0.027
positive regulation of catalytic activity	GO:0043085	118	0.027
immune system process	GO:0002376	347	0.026
macromolecular complex assembly	GO:0065003	256	0.026
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.026
regulation of translational elongation	GO:0006448	1	0.025
protein catabolic process	GO:0030163	101	0.025
establishment or maintenance of cell polarity	GO:0007163	167	0.024
positive regulation of catabolic process	GO:0009896	105	0.024
regulation of mitotic cell cycle	GO:0007346	190	0.024
sex differentiation	GO:0007548	81	0.022	Worm
anatomical structure homeostasis	GO:0060249	97	0.022
regulation of cellular response to stress	GO:0080135	89	0.022
negative regulation of apoptotic process	GO:0043066	63	0.022
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.022
endocytosis	GO:0006897	310	0.021
regulation of cellular amine metabolic process	GO:0033238	3	0.021
neuron death	GO:0070997	27	0.021
positive regulation of signal transduction	GO:0009967	223	0.021
posttranscriptional gene silencing	GO:0016441	46	0.021
cellular response to chemical stimulus	GO:0070887	199	0.021
positive regulation of multicellular organism growth	GO:0040018	21	0.020
reproductive system development	GO:0061458	74	0.020	Worm
protein localization	GO:0008104	284	0.020
meiotic cell cycle process	GO:1903046	132	0.020
establishment of planar polarity	GO:0001736	87	0.020
transcription from rna polymerase ii promoter	GO:0006366	368	0.020
positive regulation of multicellular organismal process	GO:0051240	143	0.020
eye development	GO:0001654	323	0.019
regulation of cell death	GO:0010941	173	0.019
cellular response to dna damage stimulus	GO:0006974	223	0.019
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.019
organic substance transport	GO:0071702	257	0.019
locomotory behavior	GO:0007626	176	0.019
tube development	GO:0035295	244	0.018
response to heat	GO:0009408	63	0.018
regulation of catalytic activity	GO:0050790	185	0.018
positive regulation of translation	GO:0045727	12	0.018
regulation of phosphorylation	GO:0042325	147	0.018
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.018
regulation of kinase activity	GO:0043549	53	0.018
protein modification by small protein conjugation or removal	GO:0070647	106	0.018
positive regulation of growth	GO:0045927	75	0.018
detection of chemical stimulus	GO:0009593	93	0.017
negative regulation of mitotic cell cycle	GO:0045930	109	0.017
response to oxygen containing compound	GO:1901700	200	0.017
imaginal disc derived appendage development	GO:0048737	399	0.017
positive regulation of molecular function	GO:0044093	136	0.017
response to external biotic stimulus	GO:0043207	293	0.017
wnt signaling pathway	GO:0016055	98	0.017
regulation of anatomical structure morphogenesis	GO:0022603	242	0.016
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.016
protein modification by small protein conjugation	GO:0032446	79	0.016
cellular nitrogen compound catabolic process	GO:0044270	165	0.016
catabolic process	GO:0009056	409	0.016
positive regulation of peptidase activity	GO:0010952	29	0.016
negative regulation of biosynthetic process	GO:0009890	277	0.016
cytoplasm organization	GO:0007028	64	0.016
nuclear transport	GO:0051169	72	0.015
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.015
salivary gland morphogenesis	GO:0007435	145	0.015
negative regulation of cell cycle process	GO:0010948	109	0.015
proteolysis	GO:0006508	192	0.015
regulation of catabolic process	GO:0009894	170	0.015
negative regulation of cellular biosynthetic process	GO:0031327	277	0.015
response to organic substance	GO:0010033	284	0.015
axis specification	GO:0009798	167	0.014
regulation of cell cycle process	GO:0010564	181	0.014
negative regulation of neuron death	GO:1901215	18	0.014
posttranscriptional gene silencing by rna	GO:0035194	45	0.014
response to abiotic stimulus	GO:0009628	341	0.014
positive regulation of protein phosphorylation	GO:0001934	34	0.014
positive regulation of cell migration	GO:0030335	2	0.014
nucleobase containing compound transport	GO:0015931	56	0.014
cellular macromolecule catabolic process	GO:0044265	136	0.013
negative regulation of cell death	GO:0060548	81	0.013
single organism intracellular transport	GO:1902582	207	0.013
defense response	GO:0006952	300	0.013
positive regulation of cellular component biogenesis	GO:0044089	80	0.013
centriole assembly	GO:0098534	24	0.013
genitalia development	GO:0048806	26	0.013
organelle assembly	GO:0070925	198	0.013
immune response regulating signaling pathway	GO:0002764	2	0.013
neuron apoptotic process	GO:0051402	17	0.013
positive regulation of protein modification process	GO:0031401	58	0.012
phagocytosis	GO:0006909	215	0.012
cellular amino acid metabolic process	GO:0006520	61	0.012
regulation of cellular ketone metabolic process	GO:0010565	3	0.012
chromosome segregation	GO:0007059	157	0.012
establishment of organelle localization	GO:0051656	122	0.012
central nervous system development	GO:0007417	201	0.012
morphogenesis of follicular epithelium	GO:0016333	36	0.012
peptidyl tyrosine modification	GO:0018212	24	0.012
development of primary sexual characteristics	GO:0045137	50	0.011	Worm
regulation of neuron death	GO:1901214	26	0.011
dna integrity checkpoint	GO:0031570	81	0.011
positive regulation of execution phase of apoptosis	GO:1900119	4	0.011
regulation of cysteine type endopeptidase activity	GO:2000116	27	0.011
dna replication	GO:0006260	48	0.011
deactivation of rhodopsin mediated signaling	GO:0016059	17	0.011
aromatic compound catabolic process	GO:0019439	166	0.011
gene silencing	GO:0016458	138	0.011
response to hexose	GO:0009746	3	0.011
tissue morphogenesis	GO:0048729	297	0.011
regulation of endopeptidase activity	GO:0052548	36	0.011
tissue homeostasis	GO:0001894	36	0.011
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.011
cellular macromolecular complex assembly	GO:0034622	153	0.011
male gamete generation	GO:0048232	201	0.011
negative regulation of cellular protein metabolic process	GO:0032269	85	0.011
cellular catabolic process	GO:0044248	372	0.011
cellular amine metabolic process	GO:0044106	12	0.011
head development	GO:0060322	135	0.010
chemotaxis	GO:0006935	249	0.010
positive regulation of programmed cell death	GO:0043068	62	0.010
negative regulation of cellular component organization	GO:0051129	108	0.010
negative regulation of cell communication	GO:0010648	223	0.010
morphogenesis of an epithelium	GO:0002009	276	0.010
protein complex assembly	GO:0006461	200	0.010

RpS13 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.123
immune system disease	DOID:2914	0.083
hematopoietic system disease	DOID:74	0.083
anemia	DOID:2355	0.083
bone marrow disease	DOID:4961	0.083
aplastic anemia	DOID:12449	0.083
congenital hypoplastic anemia	DOID:1342	0.079
diamond blackfan anemia	DOID:1339	0.012

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