Drosophila melanogaster

72 known processes

Klp10A (Dmel_CG1453)

CG1453 gene product from transcript CG1453-RA

(Aliases: anon-WO03040301.142,KLP10A,DmKLP10A,Kif2A,klp10A,Dmel\CG1453,DmCG1453,KLP10a,DmKlp10A,CG1453,KIF2A)

Klp10A biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
centrosome duplicationGO:00512981210.998
mitotic spindle organizationGO:00070522200.997
microtubule organizing center organizationGO:00310231680.993
centrosome cycleGO:00070981370.989
spindle organizationGO:00070512530.976
centrosome organizationGO:00512971630.973
sister chromatid segregationGO:0000819920.962
meiotic nuclear divisionGO:00071261510.960
chromosome segregationGO:00070591570.960
organelle fissionGO:00482853400.950
spindle assemblyGO:0051225800.926
meiotic cell cycle processGO:19030461320.918
spindle assembly involved in meiosisGO:0090306200.914
nuclear divisionGO:00002803320.900
organelle assemblyGO:00709251980.898
chromosome organizationGO:00512763600.865
macromolecular complex assemblyGO:00650032560.831
establishment of localization in cellGO:00516494020.806
microtubule polymerization or depolymerizationGO:0031109390.756
Human Worm
mitotic nuclear divisionGO:00070672130.729
male meiosisGO:0007140520.712
cellular macromolecular complex assemblyGO:00346221530.703
Worm
protein modification processGO:00362114380.636
regulation of protein metabolic processGO:00512462560.629
establishment of spindle orientationGO:0051294180.617
cellular protein complex assemblyGO:0043623710.591
Worm
centrosome separationGO:0051299200.555
meiosis iGO:0007127590.547
regulation of cell cycle phase transitionGO:19019871300.541
regulation of mitotic cell cycleGO:00073461900.539
spindle assembly involved in female meiosis iGO:000705750.532
mitotic sister chromatid segregationGO:0000070870.530
spindle assembly involved in mitosisGO:0090307500.515
meiotic spindle organizationGO:0000212360.492
protein complex biogenesisGO:00702712010.486
oocyte microtubule cytoskeleton organizationGO:0016325350.479
mitotic spindle elongationGO:0000022810.479
protein localizationGO:00081042840.468
meiotic cell cycleGO:00513211710.426
cellular protein modification processGO:00064644380.421
protein polymerizationGO:0051258420.401
Worm
protein complex assemblyGO:00064612000.382
regulation of organelle organizationGO:00330431960.350
establishment or maintenance of cell polarityGO:00071631670.323
spindle elongationGO:0051231830.320
regulation of cellular protein metabolic processGO:00322682430.314
centriole assemblyGO:0098534240.295
regulation of microtubule cytoskeleton organizationGO:0070507410.293
regulation of cell cycleGO:00517262910.293
cell divisionGO:00513012480.283
Worm
embryo development ending in birth or egg hatchingGO:00097921520.271
Worm
meiotic chromosome segregationGO:0045132590.267
Worm
cellular macromolecule localizationGO:00707272200.246
positive regulation of macromolecule metabolic processGO:00106044050.234
female meiosis iGO:000714480.223
vesicle mediated transportGO:00161923810.215
spermatid differentiationGO:00485151140.206
mitotic cell cycle phase transitionGO:00447721380.192
spindle assembly involved in female meiosisGO:0007056140.188
oocyte differentiationGO:00099941450.187
chromatin organizationGO:00063252070.172
spermatid developmentGO:0007286980.168
ubiquitin homeostasisGO:001099210.155
regulation of mitotic cell cycle phase transitionGO:19019901300.153
maintenance of protein location in cellGO:0032507260.152
centriole centriole cohesionGO:001045750.149
cellular protein localizationGO:00346131600.147
positive regulation of protein metabolic processGO:00512471280.142
cell proliferationGO:00082832990.138
macromolecular complex disassemblyGO:0032984370.136
Human Worm
positive regulation of nucleic acid templated transcriptionGO:19035082660.132
positive regulation of proteasomal protein catabolic processGO:1901800200.131
positive regulation of cellular protein metabolic processGO:00322701180.127
regulation of mitotic spindle organizationGO:006023690.126
oocyte axis specificationGO:00073091080.120
negative regulation of multicellular organismal processGO:00512411420.119
single organism intracellular transportGO:19025822070.118
microtubule bundle formationGO:0001578270.113
cell cycle phase transitionGO:00447701400.111
dna conformation changeGO:00711031050.107
establishment or maintenance of cytoskeleton polarityGO:0030952440.104
Human
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.104
segmentationGO:00352822070.103
intracellular transportGO:00469072280.103
mitotic spindle stabilizationGO:004314860.102
microtubule cytoskeleton organization involved in mitosisGO:1902850520.101
establishment of cell polarityGO:0030010400.099
oocyte developmentGO:00485991240.096
microtubule anchoringGO:0034453110.096
oocyte constructionGO:00073081120.095
endocytosisGO:00068973100.094
intercellular bridge organizationGO:0043063140.089
regulation of cell cycle processGO:00105641810.087
embryonic pattern specificationGO:00098801740.086
protein modification by small protein conjugation or removalGO:00706471060.085
pole plasm mrna localizationGO:0019094490.084
translationGO:0006412690.084
larval developmentGO:00021641040.081
developmental maturationGO:00217001720.080
rna localizationGO:00064031150.079
negative regulation of cellular biosynthetic processGO:00313272770.078
cellular component disassemblyGO:0022411460.078
Human Worm
negative regulation of developmental processGO:00510932010.073
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.072
Human
attachment of spindle microtubules to kinetochoreGO:000860850.071
cytokinesisGO:0000910900.070
Worm
cell maturationGO:00484691440.069
regulation of cytoskeleton organizationGO:0051493890.068
regulation of transcription from rna polymerase ii promoterGO:00063573780.068
single organism cellular localizationGO:19025801800.066
intracellular mrna localizationGO:0008298660.064
maintenance of locationGO:0051235730.064
protein complex disassemblyGO:0043241360.063
Human Worm
negative regulation of cell cycle phase transitionGO:19019881030.063
positive regulation of macromolecule biosynthetic processGO:00105572830.061
pronuclear migrationGO:003504640.061
regulation of neuron differentiationGO:00456641030.061
centriole replicationGO:0007099240.058
organelle localizationGO:00516401480.058
development of primary sexual characteristicsGO:0045137500.057
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.056
positive regulation of multicellular organismal processGO:00512401430.054
posttranscriptional regulation of gene expressionGO:00106081450.054
female meiotic divisionGO:0007143700.054
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.054
maternal determination of anterior posterior axis embryoGO:0008358740.053
regulation of protein complex disassemblyGO:0043244290.052
regulation of translationGO:0006417560.051
maintenance of protein locationGO:0045185280.050
regulation of mitosisGO:0007088560.050
regulation of mitotic sister chromatid separationGO:0010965280.049
blastoderm segmentationGO:00073501590.048
chromosome condensationGO:0030261410.048
positive regulation of rna metabolic processGO:00512542710.048
negative regulation of protein metabolic processGO:0051248850.047
mitotic centrosome separationGO:000710080.047
negative regulation of mitotic cell cycle phase transitionGO:19019911030.046
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.046
positive regulation of rna biosynthetic processGO:19026802660.046
response to abiotic stimulusGO:00096283410.045
regulation of microtubule polymerization or depolymerizationGO:0031110270.045
catabolic processGO:00090564090.045
cellular catabolic processGO:00442483720.044
positive regulation of gene expressionGO:00106282900.044
regulation of localizationGO:00328792750.043
regulation of protein modification processGO:00313991120.042
cellular component assembly involved in morphogenesisGO:00109271510.041
nucleocytoplasmic transportGO:0006913720.041
establishment of mitotic spindle orientationGO:0000132130.041
protein depolymerizationGO:0051261310.040
Human Worm
positive regulation of response to stimulusGO:00485843230.039
regulation of nuclear divisionGO:0051783580.038
positive regulation of transcription dna templatedGO:00458932660.038
regulation of mitotic sister chromatid segregationGO:0033047280.038
positive regulation of organelle organizationGO:0010638650.037
negative regulation of cell developmentGO:0010721620.037
actin cytoskeleton organizationGO:00300362060.037
microtubule based movementGO:0007018510.037
regulation of cellular component biogenesisGO:00440872010.037
pole cell developmentGO:0007277260.037
transcription from rna polymerase ii promoterGO:00063663680.037
male meiosis chromosome segregationGO:0007060100.037
single fertilizationGO:0007338240.036
positive regulation of signal transductionGO:00099672230.036
deathGO:00162652840.036
establishment of spindle localizationGO:0051293220.035
mitotic cell cycle embryonicGO:0045448380.035
nucleoside triphosphate metabolic processGO:00091411200.035
protein localization to organelleGO:0033365820.035
cytoplasmic microtubule organizationGO:0031122220.035
mitotic spindle checkpointGO:0071174110.034
negative regulation of macromolecule biosynthetic processGO:00105582700.034
metaphase plate congressionGO:0051310190.034
negative regulation of cellular protein metabolic processGO:0032269850.033
positive regulation of proteolysisGO:0045862520.033
proteolysisGO:00065081920.032
cell cycle comprising mitosis without cytokinesisGO:0033301250.032
oocyte dorsal ventral axis specificationGO:0007310340.032
spindle localizationGO:0051653220.032
macromolecule catabolic processGO:00090571610.032
cellular protein complex disassemblyGO:0043624350.032
Human Worm
positive regulation of protein modification processGO:0031401580.031
negative regulation of cytoskeleton organizationGO:0051494300.031
nucleus localizationGO:0051647340.031
negative regulation of gene expressionGO:00106293870.031
ubiquitin dependent protein catabolic processGO:0006511780.031
aromatic compound catabolic processGO:00194391660.031
mitotic chromosome condensationGO:0007076220.031
regulation of oocyte developmentGO:0060281270.031
photoreceptor cell developmentGO:0042461960.030
body morphogenesisGO:001017120.029
metaphase anaphase transition of mitotic cell cycleGO:0007091280.029
positive regulation of cellular biosynthetic processGO:00313283160.029
negative regulation of biosynthetic processGO:00098902770.029
cell deathGO:00082192790.029
chromatin modificationGO:00165681470.028
cellular macromolecule catabolic processGO:00442651360.028
maintenance of location in cellGO:0051651280.028
meiotic sister chromatid segregationGO:004514460.027
regulation of cellular localizationGO:00603411360.027
regulation of cellular protein catabolic processGO:1903362440.027
regulation of catalytic activityGO:00507901850.027
microtubule polymerizationGO:0046785150.027
Worm
negative regulation of neurogenesisGO:0050768530.027
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.026
response to temperature stimulusGO:00092661060.026
anterior posterior axis specification embryoGO:00085951030.026
regulation of spindle elongationGO:003288710.026
mitotic cell cycle checkpointGO:0007093880.025
oocyte anterior posterior axis specificationGO:0007314720.025
anterior posterior axis specificationGO:00099481090.025
positive regulation of mitotic sister chromatid separationGO:1901970100.025
phosphorylationGO:00163102940.025
eye morphogenesisGO:00485922600.025
protein localization to cytoskeletonGO:004438020.024
mitotic sister chromatid separationGO:0051306300.024
positive regulation of growthGO:0045927750.024
regulation of cell divisionGO:0051302720.023
microtubule depolymerizationGO:0007019250.023
Human Worm
establishment of mitotic spindle localizationGO:0040001170.023
g2 m transition of mitotic cell cycleGO:0000086190.023
intracellular mrna localization involved in pattern specification processGO:0060810560.023
covalent chromatin modificationGO:00165691060.023
positive regulation of nitrogen compound metabolic processGO:00511733540.023
protein transportGO:00150311550.023
spermatogenesisGO:00072832000.022
regulation of microtubule based processGO:0032886490.022
somatic stem cell divisionGO:0048103370.022
axis specificationGO:00097981670.022
regulation of spindle organizationGO:0090224170.022
programmed cell deathGO:00125012570.022
organophosphate catabolic processGO:00464341120.022
chromosome separationGO:0051304420.021
embryonic cleavageGO:004001650.021
proteolysis involved in cellular protein catabolic processGO:0051603830.021
positive regulation of nucleobase containing compound metabolic processGO:00459353320.021
regulation of protein localizationGO:0032880760.020
anterior posterior pattern specificationGO:00099521360.020
positive regulation of mitotic metaphase anaphase transitionGO:0045842100.020
organonitrogen compound metabolic processGO:19015643180.020
positive regulation of cellular component organizationGO:00511301560.020
positive regulation of nervous system developmentGO:0051962690.020
modification dependent protein catabolic processGO:0019941780.019
cytoplasmic transportGO:00164821300.019
histone modificationGO:00165701060.019
organic substance catabolic processGO:19015753080.019
gland developmentGO:00487321910.019
negative regulation of molecular functionGO:0044092510.019
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.019
fertilizationGO:0009566260.018
negative regulation of cell cycle processGO:00109481090.018
regulation of protein catabolic processGO:0042176550.018
regulation of mitotic metaphase anaphase transitionGO:0030071260.018
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.018
negative regulation of organelle organizationGO:0010639560.018
cellular protein catabolic processGO:0044257830.018
actin filament organizationGO:00070151260.017
establishment of protein localizationGO:00451841630.017
ribonucleoside monophosphate catabolic processGO:0009158390.017
regulation of molecular functionGO:00650092170.017
regulation of nucleocytoplasmic transportGO:0046822350.017
positive regulation of cell communicationGO:00106472500.017
regulation of mitotic spindle elongationGO:003288810.017
regulation of cellular response to stressGO:0080135890.017
negative regulation of translationGO:0017148280.017
axon developmentGO:00615642970.017
sensory organ morphogenesisGO:00905962600.017
positive regulation of catabolic processGO:00098961050.017
positive regulation of biosynthetic processGO:00098913160.016
small gtpase mediated signal transductionGO:0007264880.016
nuclear migrationGO:0007097200.016
negative regulation of protein depolymerizationGO:1901880230.016
negative regulation of mitotic cell cycleGO:00459301090.016
regulation of cell developmentGO:00602842150.016
regulation of ras protein signal transductionGO:0046578930.016
positive regulation of catalytic activityGO:00430851180.016
ribonucleoside triphosphate catabolic processGO:00092031080.015
cellular nitrogen compound catabolic processGO:00442701650.015
pronuclear fusionGO:000734440.015
negative regulation of cell differentiationGO:00455961430.015
regulation of intracellular signal transductionGO:19025312360.015
negative regulation of nervous system developmentGO:0051961920.015
regulation of multicellular organismal developmentGO:20000264140.015
positive regulation of signalingGO:00230562430.015
photoreceptor cell differentiationGO:00465301700.015
microtubule nucleationGO:000702080.015
Worm
positive regulation of cell proliferationGO:0008284470.015
regulation of hemocyte proliferationGO:0035206370.014
purine ribonucleoside metabolic processGO:00461281270.014
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.014
organic cyclic compound catabolic processGO:19013611680.014
stem cell proliferationGO:0072089880.014
male meiosis cytokinesisGO:0007112260.014
metaphase anaphase transition of cell cycleGO:0044784280.014
modification dependent macromolecule catabolic processGO:0043632790.014
nucleoside phosphate catabolic processGO:19012921100.014
purine nucleotide catabolic processGO:00061951090.014
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.013
meiosis iiGO:0007135230.013
regulation of metaphase anaphase transition of cell cycleGO:1902099260.013
regulation of transferase activityGO:0051338580.013
positive regulation of protein transportGO:0051222370.013
heterocycle catabolic processGO:00467001660.013
positive regulation of mitotic cell cycle phase transitionGO:1901992200.013
cytoplasm organizationGO:0007028640.013
pole plasm assemblyGO:0007315610.013
organic substance transportGO:00717022570.013
negative regulation of microtubule depolymerizationGO:0007026210.013
positive regulation of phosphorylationGO:0042327870.013
protein catabolic processGO:00301631010.013
purine nucleoside monophosphate catabolic processGO:0009128380.012
protein phosphorylationGO:00064681690.012
regulation of cell maturationGO:1903429270.012
regulation of cell proliferationGO:00421271630.012
cytoskeleton dependent cytokinesisGO:0061640810.012
regulation of chromosome organizationGO:0033044640.012
regulation of endocytosisGO:0030100370.012
regulation of wnt signaling pathwayGO:0030111680.012
regulation of phosphorus metabolic processGO:00511742100.012
positive regulation of cellular protein catabolic processGO:1903364240.012
regulation of cell shapeGO:00083601130.012
regulation of small gtpase mediated signal transductionGO:0051056930.012
regulation of response to stressGO:00801342000.012
glycosyl compound metabolic processGO:19016571270.011
nuclear transportGO:0051169720.011
regulation of protein depolymerizationGO:1901879270.011
regulation of catabolic processGO:00098941700.011
positive regulation of protein catabolic processGO:0045732340.011
organophosphate metabolic processGO:00196371950.011
embryonic axis specificationGO:00005781070.011
regulation of proteolysisGO:0030162870.011
neural precursor cell proliferationGO:0061351750.011
positive regulation of metaphase anaphase transition of cell cycleGO:1902101100.011
regulation of pole plasm oskar mrna localizationGO:0007317270.011
nucleus organizationGO:0006997450.011
phagocytosisGO:00069092150.011
regulation of synapse structure and activityGO:00508031280.011
positive regulation of mitotic cell cycleGO:0045931340.011
regulation of phosphate metabolic processGO:00192202100.011
regulation of protein transportGO:0051223570.011
mitotic spindle assembly checkpointGO:0007094110.011
protein polyubiquitinationGO:0000209110.010
cytokinetic processGO:0032506270.010
peptidyl threonine modificationGO:001821030.010
negative regulation of cellular metabolic processGO:00313243820.010
signal transduction by phosphorylationGO:00230141070.010
chemotaxisGO:00069352490.010
nuclear importGO:0051170510.010
dna metabolic processGO:00062592270.010
regulation of chromosome segregationGO:0051983320.010
Human
histolysisGO:00075591020.010
peptidyl threonine phosphorylationGO:001810720.010
purine nucleoside catabolic processGO:00061521120.010
glycosyl compound catabolic processGO:19016581120.010
asymmetric neuroblast divisionGO:0055059330.010
negative regulation of mitotic sister chromatid separationGO:2000816130.010
membrane organizationGO:00610241120.010
positive regulation of cellular component biogenesisGO:0044089800.010
positive regulation of phosphate metabolic processGO:00459371390.010
compound eye developmentGO:00487493070.010
protein maturationGO:0051604710.010

Klp10A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.033
disease of cellular proliferationDOID:1456600.033
cancerDOID:16200.033
disease of anatomical entityDOID:700.023