IMP: Integrative Multi-species Prediction

Drosophila melanogaster

9 known processes

CG14684 (Dmel_CG14684)

CG14684 gene product from transcript CG14684-RA

(Aliases: Dmel\CG14684)

FLYBASE: FBgn0037824
Entrez: 41281
UniProtKB: Q9VGY3

Process Predictions
Disease Predictions

CG14684 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
muscle structure development	GO:0061061	224	0.045
body morphogenesis	GO:0010171	2	0.042
negative regulation of developmental growth	GO:0048640	64	0.035
respiratory system development	GO:0060541	213	0.035
regulation of cell cycle	GO:0051726	291	0.033
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.032
organelle fission	GO:0048285	340	0.030
single organism behavior	GO:0044708	391	0.030
protein complex biogenesis	GO:0070271	201	0.029
growth	GO:0040007	359	0.029
cardiocyte differentiation	GO:0035051	29	0.028
muscle organ development	GO:0007517	127	0.028
nuclear division	GO:0000280	332	0.028
negative regulation of developmental process	GO:0051093	201	0.028
organonitrogen compound metabolic process	GO:1901564	318	0.027
organ growth	GO:0035265	56	0.027
protein complex assembly	GO:0006461	200	0.026
regulation of anatomical structure size	GO:0090066	163	0.025
actin filament based process	GO:0030029	220	0.023
imaginal disc derived appendage development	GO:0048737	399	0.023
regulation of localization	GO:0032879	275	0.023
regulation of transport	GO:0051049	181	0.023
organic substance transport	GO:0071702	257	0.022
negative regulation of growth	GO:0045926	84	0.022
tissue morphogenesis	GO:0048729	297	0.021
protein modification process	GO:0036211	438	0.021
developmental growth	GO:0048589	280	0.021
segmentation	GO:0035282	207	0.020
imaginal disc derived wing morphogenesis	GO:0007476	337	0.020
post embryonic appendage morphogenesis	GO:0035120	385	0.020
homeostatic process	GO:0042592	199	0.020
regulation of cell differentiation	GO:0045595	302	0.020
multicellular organismal reproductive behavior	GO:0033057	110	0.019
regulation of cellular amine metabolic process	GO:0033238	3	0.019
cellular response to dna damage stimulus	GO:0006974	223	0.019
cellular amine metabolic process	GO:0044106	12	0.018
amine metabolic process	GO:0009308	12	0.018
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.018
multi organism behavior	GO:0051705	175	0.018
appendage development	GO:0048736	401	0.018
striated muscle cell differentiation	GO:0051146	90	0.018
dendrite morphogenesis	GO:0048813	199	0.018
mating behavior	GO:0007617	106	0.017
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.017
positive regulation of rna biosynthetic process	GO:1902680	266	0.017
protein catabolic process	GO:0030163	101	0.017
small molecule metabolic process	GO:0044281	305	0.017
heart development	GO:0007507	82	0.017
establishment of localization in cell	GO:0051649	402	0.017
regulation of developmental growth	GO:0048638	174	0.016
single organism biosynthetic process	GO:0044711	206	0.016
sperm storage	GO:0046693	10	0.016
regulation of organ growth	GO:0046620	42	0.016
response to oxygen containing compound	GO:1901700	200	0.016
oxoacid metabolic process	GO:0043436	103	0.016
negative regulation of cell development	GO:0010721	62	0.016
taxis	GO:0042330	304	0.016
regulation of cell development	GO:0060284	215	0.016
vesicle mediated transport	GO:0016192	381	0.015
central nervous system development	GO:0007417	201	0.015
gland development	GO:0048732	191	0.015
macromolecular complex assembly	GO:0065003	256	0.015
negative regulation of gene expression	GO:0010629	387	0.015
negative regulation of organ growth	GO:0046621	15	0.015
extracellular matrix organization	GO:0030198	32	0.015
morphogenesis of an epithelium	GO:0002009	276	0.015
cellular protein modification process	GO:0006464	438	0.015
regulation of cellular protein metabolic process	GO:0032268	243	0.015
positive regulation of response to stimulus	GO:0048584	323	0.015
regulation of multicellular organismal development	GO:2000026	414	0.015
regulation of cell cycle process	GO:0010564	181	0.015
multi organism reproductive behavior	GO:0044705	121	0.015
phosphorylation	GO:0016310	294	0.015
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.014
organophosphate metabolic process	GO:0019637	195	0.014
axonogenesis	GO:0007409	290	0.014
regulation of cellular amino acid metabolic process	GO:0006521	0	0.014
carboxylic acid metabolic process	GO:0019752	92	0.014
wing disc morphogenesis	GO:0007472	344	0.014
regulation of protein metabolic process	GO:0051246	256	0.014
response to organic substance	GO:0010033	284	0.014
endocytosis	GO:0006897	310	0.014
cellular amino acid metabolic process	GO:0006520	61	0.014
regionalization	GO:0003002	416	0.014
cellular macromolecule localization	GO:0070727	220	0.014
epithelial cell differentiation	GO:0030855	322	0.014
insemination	GO:0007320	22	0.014
regulation of cellular ketone metabolic process	GO:0010565	3	0.014
proteolysis	GO:0006508	192	0.014
appendage morphogenesis	GO:0035107	397	0.014
phagocytosis	GO:0006909	215	0.014
regulation of mitotic cell cycle	GO:0007346	190	0.014
cell growth	GO:0016049	108	0.014
positive regulation of biosynthetic process	GO:0009891	316	0.014
reproductive behavior	GO:0019098	122	0.014
positive regulation of macromolecule metabolic process	GO:0010604	405	0.014
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.014
catabolic process	GO:0009056	409	0.014
positive regulation of cell motility	GO:2000147	3	0.014
positive regulation of multicellular organismal process	GO:0051240	143	0.014
head development	GO:0060322	135	0.013
tube development	GO:0035295	244	0.013
negative regulation of cellular metabolic process	GO:0031324	382	0.013
negative regulation of multicellular organismal process	GO:0051241	142	0.013
multi multicellular organism process	GO:0044706	123	0.013
cellular macromolecule catabolic process	GO:0044265	136	0.013
striated muscle cell development	GO:0055002	50	0.013
cell cycle checkpoint	GO:0000075	95	0.013
macromolecule catabolic process	GO:0009057	161	0.013
positive regulation of signal transduction	GO:0009967	223	0.013
chromatin organization	GO:0006325	207	0.013
spermatogenesis	GO:0007283	200	0.013
carbohydrate derivative metabolic process	GO:1901135	217	0.013
single organism intracellular transport	GO:1902582	207	0.013
exocrine system development	GO:0035272	162	0.013
regulation of growth	GO:0040008	233	0.013
single organism membrane organization	GO:0044802	93	0.013
ethanolamine containing compound metabolic process	GO:0042439	4	0.012
organic acid metabolic process	GO:0006082	103	0.012
muscle adaptation	GO:0043500	1	0.012
male gamete generation	GO:0048232	201	0.012
microtubule organizing center organization	GO:0031023	168	0.012
protein phosphorylation	GO:0006468	169	0.012
intracellular signal transduction	GO:0035556	300	0.012
positive regulation of gene expression	GO:0010628	290	0.012
response to hexose	GO:0009746	3	0.012
regulation of system process	GO:0044057	36	0.012
dendrite development	GO:0016358	204	0.012
positive regulation of transcription dna templated	GO:0045893	266	0.012
open tracheal system development	GO:0007424	204	0.012
positive regulation of cellular biosynthetic process	GO:0031328	316	0.012
positive regulation of cell communication	GO:0010647	250	0.012
forebrain development	GO:0030900	2	0.012
protein transport	GO:0015031	155	0.012
regulation of epithelial cell differentiation	GO:0030856	4	0.012
cell cycle phase transition	GO:0044770	140	0.012
circulatory system development	GO:0072359	82	0.012
organic substance catabolic process	GO:1901575	308	0.012
positive regulation of signaling	GO:0023056	243	0.012
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.012
spindle organization	GO:0007051	253	0.012
positive regulation of rna metabolic process	GO:0051254	271	0.012
cardiovascular system development	GO:0072358	82	0.012
cell recognition	GO:0008037	102	0.011
cellular protein localization	GO:0034613	160	0.011
organelle assembly	GO:0070925	198	0.011
response to lipopolysaccharide	GO:0032496	4	0.011
intracellular transport	GO:0046907	228	0.011
cellular ketone metabolic process	GO:0042180	24	0.011
muscle cell differentiation	GO:0042692	103	0.011
positive regulation of transport	GO:0051050	92	0.011
maintenance of location	GO:0051235	73	0.011
rna processing	GO:0006396	147	0.011
negative regulation of biosynthetic process	GO:0009890	277	0.011
muscle cell development	GO:0055001	50	0.011
chromosome organization	GO:0051276	360	0.011
mitotic spindle organization	GO:0007052	220	0.011
membrane organization	GO:0061024	112	0.011
cellular catabolic process	GO:0044248	372	0.011
dna integrity checkpoint	GO:0031570	81	0.011
dna metabolic process	GO:0006259	227	0.011
camera type eye development	GO:0043010	4	0.011
chemical homeostasis	GO:0048878	92	0.011
sperm individualization	GO:0007291	48	0.011
sister chromatid segregation	GO:0000819	92	0.011
cellular response to starvation	GO:0009267	61	0.011
single organism catabolic process	GO:0044712	228	0.010
modification dependent protein catabolic process	GO:0019941	78	0.010
endomembrane system organization	GO:0010256	119	0.010
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.010
cell proliferation	GO:0008283	299	0.010
cell death	GO:0008219	279	0.010
adult locomotory behavior	GO:0008344	76	0.010
cellular component assembly involved in morphogenesis	GO:0010927	151	0.010
response to extracellular stimulus	GO:0009991	116	0.010
antimicrobial humoral response	GO:0019730	99	0.010
sperm competition	GO:0046692	21	0.010

CG14684 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.055
disease of metabolism	DOID:0014667	0.019
nervous system disease	DOID:863	0.017
musculoskeletal system disease	DOID:17	0.013
connective tissue disease	DOID:65	0.013
sensory system disease	DOID:0050155	0.011
disease of cellular proliferation	DOID:14566	0.010
cancer	DOID:162	0.010

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