IMP: Integrative Multi-species Prediction

Drosophila melanogaster

176 known processes

krz (Dmel_CG1487)

kurtz

(Aliases: Krz,l(3)S095214,Kurz,CG1487,0952/14,Dmel\CG1487)

FLYBASE: FBgn0040206
Entrez: 53554
UniProtKB: Q9V393

Process Predictions
Disease Predictions

krz biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
negative regulation of signal transduction	GO:0009968	206	0.972
immune system process	GO:0002376	347	0.964
negative regulation of response to stimulus	GO:0048585	258	0.923
negative regulation of signaling	GO:0023057	219	0.907
regulation of immune response	GO:0050776	118	0.816	Mouse
cellular ketone metabolic process	GO:0042180	24	0.770
cellular protein modification process	GO:0006464	438	0.730
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.698
negative regulation of intracellular signal transduction	GO:1902532	57	0.696
negative regulation of cell communication	GO:0010648	223	0.685
regulation of growth	GO:0040008	233	0.662	Worm
carboxylic acid metabolic process	GO:0019752	92	0.621
peptidyl amino acid modification	GO:0018193	105	0.578
immune response activating signal transduction	GO:0002757	2	0.549	Mouse
epithelial cell differentiation	GO:0030855	322	0.510
regulation of cellular amino acid metabolic process	GO:0006521	0	0.509
negative regulation of cellular metabolic process	GO:0031324	382	0.507
imaginal disc derived wing morphogenesis	GO:0007476	337	0.497
positive regulation of macromolecule metabolic process	GO:0010604	405	0.485
oxoacid metabolic process	GO:0043436	103	0.481
transcription from rna polymerase ii promoter	GO:0006366	368	0.471
cellular response to chemical stimulus	GO:0070887	199	0.471	Zebrafish Mouse
protein modification process	GO:0036211	438	0.464
regulation of immune system process	GO:0002682	176	0.463
regulation of cell differentiation	GO:0045595	302	0.460
innate immune response	GO:0045087	144	0.443
neuron projection guidance	GO:0097485	241	0.441
ubiquitin dependent protein catabolic process	GO:0006511	78	0.422
instar larval development	GO:0002168	55	0.415
small molecule metabolic process	GO:0044281	305	0.402
regulation of protein metabolic process	GO:0051246	256	0.396
growth	GO:0040007	359	0.372	Worm
immune response regulating signaling pathway	GO:0002764	2	0.368	Mouse
negative regulation of phosphorylation	GO:0042326	35	0.365
organic acid metabolic process	GO:0006082	103	0.364
immune response	GO:0006955	246	0.362
cellular amino acid metabolic process	GO:0006520	61	0.358
regionalization	GO:0003002	416	0.358
modification dependent protein catabolic process	GO:0019941	78	0.349
protein phosphorylation	GO:0006468	169	0.338
positive regulation of signal transduction	GO:0009967	223	0.337	Mouse
organonitrogen compound metabolic process	GO:1901564	318	0.334
regulation of protein serine threonine kinase activity	GO:0071900	25	0.333
mitotic g2 dna damage checkpoint	GO:0007095	69	0.333
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.332
axonogenesis	GO:0007409	290	0.328
negative regulation of peptidyl tyrosine phosphorylation	GO:0050732	6	0.321
negative regulation of cell proliferation	GO:0008285	69	0.314
dorsal closure	GO:0007391	79	0.313
regulation of defense response to virus	GO:0050688	14	0.313
cellular amine metabolic process	GO:0044106	12	0.305
embryonic morphogenesis	GO:0048598	206	0.302
cell division	GO:0051301	248	0.300
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.295
negative regulation of synaptic growth at neuromuscular junction	GO:0045886	39	0.294
regulation of protein phosphorylation	GO:0001932	64	0.292
wing disc morphogenesis	GO:0007472	344	0.290
hemopoiesis	GO:0030097	46	0.286
embryo development ending in birth or egg hatching	GO:0009792	152	0.286
regulation of multicellular organismal development	GO:2000026	414	0.284
defense response to bacterium	GO:0042742	178	0.282
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.264
taxis	GO:0042330	304	0.261	Zebrafish
transforming growth factor beta receptor signaling pathway	GO:0007179	16	0.257
catabolic process	GO:0009056	409	0.257
negative regulation of immune system process	GO:0002683	50	0.254
negative regulation of biosynthetic process	GO:0009890	277	0.253
modification dependent macromolecule catabolic process	GO:0043632	79	0.249
homeostatic process	GO:0042592	199	0.249	Mouse Fly
defense response to other organism	GO:0098542	225	0.248
post embryonic appendage morphogenesis	GO:0035120	385	0.247
cell proliferation	GO:0008283	299	0.243
positive regulation of signaling	GO:0023056	243	0.232	Mouse
defense response	GO:0006952	300	0.227
hematopoietic or lymphoid organ development	GO:0048534	57	0.225
response to virus	GO:0009615	28	0.222
regulation of protein kinase activity	GO:0045859	51	0.218
embryonic development via the syncytial blastoderm	GO:0001700	148	0.212
regulation of kinase activity	GO:0043549	53	0.210
appendage morphogenesis	GO:0035107	397	0.210
appendage development	GO:0048736	401	0.209
negative regulation of programmed cell death	GO:0043069	72	0.209	Mouse
developmental growth	GO:0048589	280	0.206
positive regulation of multicellular organismal process	GO:0051240	143	0.204
organic hydroxy compound metabolic process	GO:1901615	83	0.204
cellular component assembly involved in morphogenesis	GO:0010927	151	0.203
epithelial cell development	GO:0002064	274	0.195
chemotaxis	GO:0006935	249	0.194	Zebrafish
response to temperature stimulus	GO:0009266	106	0.187
positive regulation of immune response	GO:0050778	63	0.186	Mouse
amine metabolic process	GO:0009308	12	0.185
cellular protein catabolic process	GO:0044257	83	0.180
regulation of cell proliferation	GO:0042127	163	0.179
axon guidance	GO:0007411	233	0.179
positive regulation of rna metabolic process	GO:0051254	271	0.177
positive regulation of developmental process	GO:0051094	143	0.175
regulation of map kinase activity	GO:0043405	17	0.174
response to oxidative stress	GO:0006979	86	0.173
regulation of endopeptidase activity	GO:0052548	36	0.173	Mouse
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.165
production of molecular mediator of immune response	GO:0002440	46	0.164
intracellular signal transduction	GO:0035556	300	0.164	Mouse
axis specification	GO:0009798	167	0.162
developmental maturation	GO:0021700	172	0.162
response to other organism	GO:0051707	293	0.161
proteolysis	GO:0006508	192	0.161	Mouse
tube development	GO:0035295	244	0.160
regulation of developmental growth	GO:0048638	174	0.159
positive regulation of gene expression	GO:0010628	290	0.158
regulation of wnt signaling pathway	GO:0030111	68	0.156
positive regulation of biosynthetic process	GO:0009891	316	0.154
wnt signaling pathway	GO:0016055	98	0.154
negative regulation of cellular protein metabolic process	GO:0032269	85	0.151
blastoderm segmentation	GO:0007350	159	0.151
cellular macromolecule catabolic process	GO:0044265	136	0.151
eye development	GO:0001654	323	0.148
spindle organization	GO:0007051	253	0.147
imaginal disc growth	GO:0007446	37	0.145
regulation of imaginal disc growth	GO:0045570	26	0.145
regulation of apoptotic process	GO:0042981	130	0.145	Mouse
imaginal disc derived appendage development	GO:0048737	399	0.144
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.144
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.141
regulation of immune effector process	GO:0002697	52	0.140
proteasomal protein catabolic process	GO:0010498	59	0.140
positive regulation of cell migration	GO:0030335	2	0.140
regulation of cell projection organization	GO:0031344	92	0.139
regulation of cell cycle	GO:0051726	291	0.138
embryonic pattern specification	GO:0009880	174	0.137
regulation of cellular amine metabolic process	GO:0033238	3	0.136
positive regulation of antifungal peptide biosynthetic process	GO:0006967	5	0.135
oocyte development	GO:0048599	124	0.135
negative regulation of gene expression	GO:0010629	387	0.134	Mouse
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.133
response to abiotic stimulus	GO:0009628	341	0.133	Mouse Fly
regulation of response to biotic stimulus	GO:0002831	63	0.128
vesicle mediated transport	GO:0016192	381	0.128	Mouse Fly
response to external biotic stimulus	GO:0043207	293	0.127
single organism biosynthetic process	GO:0044711	206	0.126
digestive system development	GO:0055123	149	0.125
neural precursor cell proliferation	GO:0061351	75	0.123
phosphorylation	GO:0016310	294	0.122
morphogenesis of embryonic epithelium	GO:0016331	94	0.122
protein catabolic process	GO:0030163	101	0.121
cellular ion homeostasis	GO:0006873	39	0.121
negative regulation of protein phosphorylation	GO:0001933	17	0.121
molting cycle chitin based cuticle	GO:0007591	56	0.121
determination of adult lifespan	GO:0008340	137	0.120
eye morphogenesis	GO:0048592	260	0.118
cell maturation	GO:0048469	144	0.117
regulation of localization	GO:0032879	275	0.116	Zebrafish Mouse
positive regulation of response to stimulus	GO:0048584	323	0.115	Mouse
cellular response to endogenous stimulus	GO:0071495	80	0.114
regulation of defense response	GO:0031347	102	0.113
negative regulation of cellular biosynthetic process	GO:0031327	277	0.113
secretion by cell	GO:0032940	101	0.110	Mouse
digestive tract development	GO:0048565	149	0.109
synaptic transmission	GO:0007268	288	0.109	Mouse
protein acetylation	GO:0006473	39	0.108
regulation of cellular catabolic process	GO:0031329	157	0.107
mapk cascade	GO:0000165	107	0.107	Mouse
positive regulation of intracellular signal transduction	GO:1902533	116	0.106	Mouse
regulation of protein modification process	GO:0031399	112	0.105
imaginal disc derived wing vein specification	GO:0007474	48	0.105
negative regulation of phosphate metabolic process	GO:0045936	45	0.102
negative regulation of protein metabolic process	GO:0051248	85	0.100
response to organic substance	GO:0010033	284	0.099	Mouse
regulation of proteolysis	GO:0030162	87	0.098	Mouse
regulation of synaptic transmission	GO:0050804	69	0.097	Mouse
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	44	0.097
negative regulation of rna biosynthetic process	GO:1902679	240	0.097
organic substance catabolic process	GO:1901575	308	0.096
notch signaling pathway	GO:0007219	120	0.095
oocyte construction	GO:0007308	112	0.095
negative regulation of fibroblast growth factor receptor signaling pathway	GO:0040037	2	0.095
regulation of response to stress	GO:0080134	200	0.094
phagocytosis	GO:0006909	215	0.094
regulation of multi organism process	GO:0043900	131	0.093
columnar cuboidal epithelial cell development	GO:0002066	249	0.092
neuroblast proliferation	GO:0007405	74	0.092
establishment or maintenance of cell polarity	GO:0007163	167	0.092
response to biotic stimulus	GO:0009607	294	0.090
negative regulation of wnt signaling pathway	GO:0030178	28	0.090
regulation of organ growth	GO:0046620	42	0.089
synapse organization	GO:0050808	196	0.088
positive regulation of defense response	GO:0031349	59	0.088	Mouse
cell motility	GO:0048870	251	0.087	Zebrafish
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.087
oocyte axis specification	GO:0007309	108	0.086
organ growth	GO:0035265	56	0.086
regulation of canonical wnt signaling pathway	GO:0060828	15	0.085
neuromuscular junction development	GO:0007528	149	0.085
activation of mapk activity	GO:0000187	9	0.085
defense response to gram negative bacterium	GO:0050829	94	0.084
negative regulation of growth	GO:0045926	84	0.084
organic substance transport	GO:0071702	257	0.082	Mouse
larval development	GO:0002164	104	0.081
ovarian follicle cell development	GO:0030707	248	0.081
regulation of programmed cell death	GO:0043067	152	0.080	Mouse
positive regulation of immune system process	GO:0002684	68	0.080	Mouse
negative regulation of cellular response to growth factor stimulus	GO:0090288	6	0.079
connective tissue development	GO:0061448	3	0.079
dorsal ventral axis specification	GO:0009950	66	0.078
histone h4 acetylation	GO:0043967	13	0.076
metal ion transport	GO:0030001	74	0.076
regulation of jun kinase activity	GO:0043506	8	0.075
positive regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032436	19	0.074
epithelial cell migration	GO:0010631	148	0.074
signal transduction by phosphorylation	GO:0023014	107	0.073	Mouse
cuticle development	GO:0042335	86	0.073
positive regulation of proteolysis involved in cellular protein catabolic process	GO:1903052	24	0.072
regulation of notch signaling pathway	GO:0008593	100	0.072
response to oxygen containing compound	GO:1901700	200	0.072	Mouse
positive regulation of developmental growth	GO:0048639	62	0.070
positive regulation of multicellular organism growth	GO:0040018	21	0.070
synapse assembly	GO:0007416	143	0.069
regulation of response to external stimulus	GO:0032101	115	0.068
negative regulation of multicellular organismal process	GO:0051241	142	0.068
extracellular structure organization	GO:0043062	46	0.067
chorion containing eggshell formation	GO:0007304	105	0.067
regulation of cellular protein metabolic process	GO:0032268	243	0.067
regulation of cell cycle process	GO:0010564	181	0.067
regulation of phosphorylation	GO:0042325	147	0.066
immune system development	GO:0002520	57	0.066
cellular response to organic substance	GO:0071310	132	0.066	Mouse
response to heat	GO:0009408	63	0.065
stress activated mapk cascade	GO:0051403	52	0.065
negative regulation of transforming growth factor beta receptor signaling pathway	GO:0030512	4	0.065
positive regulation of protein metabolic process	GO:0051247	128	0.065
positive regulation of jun kinase activity	GO:0043507	4	0.065
molting cycle	GO:0042303	56	0.064
negative regulation of synapse assembly	GO:0051964	39	0.064
head involution	GO:0008258	35	0.063
positive regulation of rna biosynthetic process	GO:1902680	266	0.063
positive regulation of growth	GO:0045927	75	0.063	Worm
regulation of nervous system development	GO:0051960	248	0.062
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.062
cellular response to peptide hormone stimulus	GO:0071375	28	0.062
toll signaling pathway	GO:0008063	25	0.062
positive regulation of cell motility	GO:2000147	3	0.061
histone h4 k16 acetylation	GO:0043984	4	0.061
regulation of cellular protein catabolic process	GO:1903362	44	0.061
memory	GO:0007613	94	0.060
morphogenesis of an epithelium	GO:0002009	276	0.059
cell cycle phase transition	GO:0044770	140	0.058
urogenital system development	GO:0001655	72	0.058
nuclear division	GO:0000280	332	0.057
anterior posterior pattern specification	GO:0009952	136	0.057
stem cell development	GO:0048864	79	0.056
axon development	GO:0061564	297	0.056
cell death	GO:0008219	279	0.056	Mouse
positive regulation of proteasomal protein catabolic process	GO:1901800	20	0.056
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	25	0.056	Mouse
regulation of cell division	GO:0051302	72	0.056
cytokinesis	GO:0000910	90	0.055
response to bacterium	GO:0009617	198	0.055
ameboidal type cell migration	GO:0001667	151	0.055
reproductive structure development	GO:0048608	74	0.055
developmental pigmentation	GO:0048066	68	0.055
multicellular organismal aging	GO:0010259	140	0.054
multi organism behavior	GO:0051705	175	0.054
chromatin organization	GO:0006325	207	0.053
regulation of mitotic cell cycle	GO:0007346	190	0.052
autophagic vacuole assembly	GO:0000045	2	0.052
regulation of post embryonic development	GO:0048580	10	0.052
meiotic cell cycle	GO:0051321	171	0.051
stem cell proliferation	GO:0072089	88	0.050
negative regulation of phosphorus metabolic process	GO:0010563	45	0.050
lateral inhibition	GO:0046331	206	0.050
negative regulation of molecular function	GO:0044092	51	0.050
cell cycle g1 s phase transition	GO:0044843	31	0.050
regulation of stress activated mapk cascade	GO:0032872	41	0.049
peptidyl tyrosine modification	GO:0018212	24	0.049
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.049
response to nitrogen compound	GO:1901698	90	0.049
organelle assembly	GO:0070925	198	0.049
organelle fission	GO:0048285	340	0.049
hemocyte differentiation	GO:0042386	38	0.048
mitotic spindle organization	GO:0007052	220	0.048
eye photoreceptor cell development	GO:0042462	81	0.048
negative regulation of developmental process	GO:0051093	201	0.048
mitochondrion distribution	GO:0048311	10	0.048
regulation of neuron projection development	GO:0010975	69	0.048
activation of immune response	GO:0002253	5	0.047	Mouse
positive regulation of phosphorylation	GO:0042327	87	0.047	Mouse
inorganic ion transmembrane transport	GO:0098660	73	0.047
cell migration	GO:0016477	238	0.047	Zebrafish
g2 dna damage checkpoint	GO:0031572	69	0.047
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.046
negative regulation of mitotic cell cycle	GO:0045930	109	0.046
regulation of phosphate metabolic process	GO:0019220	210	0.046
dna metabolic process	GO:0006259	227	0.046
anterior posterior axis specification embryo	GO:0008595	103	0.046
regulation of cellular response to stress	GO:0080135	89	0.046
protein acylation	GO:0043543	42	0.046
regulation of reproductive process	GO:2000241	54	0.045
mitotic cell cycle checkpoint	GO:0007093	88	0.045
eye photoreceptor cell differentiation	GO:0001754	145	0.045
regulation of hemocyte differentiation	GO:0045610	22	0.045
regulation of peptidyl tyrosine phosphorylation	GO:0050730	10	0.045
maintenance of location	GO:0051235	73	0.044
synaptic growth at neuromuscular junction	GO:0051124	119	0.044
lipid storage	GO:0019915	38	0.044
extrinsic apoptotic signaling pathway	GO:0097191	1	0.043
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.043
positive regulation of i kappab kinase nf kappab signaling	GO:0043123	1	0.043
regulation of catalytic activity	GO:0050790	185	0.043
establishment of organelle localization	GO:0051656	122	0.042
regulation of neuron differentiation	GO:0045664	103	0.042
chromatin remodeling	GO:0006338	72	0.042
regulation of synapse assembly	GO:0051963	94	0.042
asymmetric stem cell division	GO:0098722	49	0.042
endocytosis	GO:0006897	310	0.042	Mouse Fly
positive regulation of protein phosphorylation	GO:0001934	34	0.041	Mouse
internal protein amino acid acetylation	GO:0006475	38	0.041
erbb signaling pathway	GO:0038127	58	0.041
negative regulation of cell cycle process	GO:0010948	109	0.041
regulation of organ morphogenesis	GO:2000027	78	0.041
ion transmembrane transport	GO:0034220	122	0.041
negative regulation of transferase activity	GO:0051348	18	0.041
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.040
positive regulation of protein serine threonine kinase activity	GO:0071902	15	0.040
death	GO:0016265	284	0.040	Mouse
neuroblast division	GO:0055057	35	0.040
peptidyl lysine acetylation	GO:0018394	39	0.040
regulation of anatomical structure size	GO:0090066	163	0.039
tor signaling	GO:0031929	32	0.039
establishment of localization in cell	GO:0051649	402	0.039	Mouse
tube morphogenesis	GO:0035239	191	0.039
positive regulation of cell communication	GO:0010647	250	0.039	Mouse
reproductive system development	GO:0061458	74	0.039
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.039
translation	GO:0006412	69	0.039
tissue migration	GO:0090130	155	0.038
regulation of antifungal peptide biosynthetic process	GO:0002810	5	0.038
stem cell division	GO:0017145	69	0.038
regulation of autophagy	GO:0010506	62	0.038
regulation of stress activated protein kinase signaling cascade	GO:0070302	42	0.038
gastrulation	GO:0007369	70	0.038
endodermal cell fate commitment	GO:0001711	3	0.037
negative regulation of cellular response to oxidative stress	GO:1900408	1	0.037
posttranscriptional regulation of gene expression	GO:0010608	145	0.037
peptidyl threonine phosphorylation	GO:0018107	2	0.036
multicellular organism growth	GO:0035264	46	0.036
protein modification by small protein removal	GO:0070646	28	0.036
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.035
immune effector process	GO:0002252	98	0.035
cellular catabolic process	GO:0044248	372	0.035
cell growth	GO:0016049	108	0.034
cellular response to dna damage stimulus	GO:0006974	223	0.034
photoreceptor cell differentiation	GO:0046530	170	0.034
regulation of production of molecular mediator of immune response	GO:0002700	44	0.034
negative regulation of notch signaling pathway	GO:0045746	41	0.034
positive regulation of catalytic activity	GO:0043085	118	0.034
oocyte microtubule cytoskeleton polarization	GO:0008103	22	0.033
gene silencing by mirna	GO:0035195	22	0.033
regulation of cellular ketone metabolic process	GO:0010565	3	0.033
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	23	0.033
cell fate specification	GO:0001708	71	0.033
apoptotic process	GO:0006915	159	0.033	Mouse
regulation of neurogenesis	GO:0050767	158	0.033
negative regulation of catalytic activity	GO:0043086	42	0.033
regulation of molecular function	GO:0065009	217	0.033
positive regulation of cellular protein metabolic process	GO:0032270	118	0.033
production of small rna involved in gene silencing by rna	GO:0070918	15	0.032
positive regulation of cell cycle	GO:0045787	43	0.032
regulation of nf kappab import into nucleus	GO:0042345	1	0.032
antifungal peptide biosynthetic process	GO:0002783	5	0.032
segmentation	GO:0035282	207	0.032
response to organic cyclic compound	GO:0014070	89	0.032
programmed cell death	GO:0012501	257	0.031	Mouse
histone modification	GO:0016570	106	0.031
compound eye photoreceptor development	GO:0042051	78	0.031
regulation of decapentaplegic signaling pathway	GO:0090097	8	0.031
negative regulation of smoothened signaling pathway	GO:0045879	16	0.031
positive regulation of phosphorus metabolic process	GO:0010562	139	0.031	Mouse
sensory organ morphogenesis	GO:0090596	260	0.031
positive regulation of proteolysis	GO:0045862	52	0.030
negative regulation of cellular component organization	GO:0051129	108	0.030
endoderm formation	GO:0001706	3	0.030
regulation of cellular component size	GO:0032535	98	0.030
oocyte differentiation	GO:0009994	145	0.030
myotube cell development	GO:0014904	3	0.030
cation transmembrane transport	GO:0098655	88	0.030
cellular response to external stimulus	GO:0071496	66	0.030
sex differentiation	GO:0007548	81	0.030
response to ionizing radiation	GO:0010212	32	0.029
regulation of tor signaling	GO:0032006	21	0.029
regulation of organelle organization	GO:0033043	196	0.029
regulation of photoreceptor cell differentiation	GO:0046532	34	0.029
regulation of cellular response to oxidative stress	GO:1900407	4	0.029
cellular nitrogen compound catabolic process	GO:0044270	165	0.029
regulation of transport	GO:0051049	181	0.029	Mouse
protein localization	GO:0008104	284	0.029
parallel actin filament bundle assembly	GO:0030046	2	0.028
negative regulation of mapk cascade	GO:0043409	23	0.028
mitochondrion organization	GO:0007005	65	0.028
regulation of pathway restricted smad protein phosphorylation	GO:0060393	1	0.028
developmental programmed cell death	GO:0010623	138	0.028
cellular response to transforming growth factor beta stimulus	GO:0071560	18	0.028
stem cell maintenance	GO:0019827	67	0.028
cellular homeostasis	GO:0019725	80	0.028	Mouse
photoreceptor cell development	GO:0042461	96	0.028
positive regulation of cellular biosynthetic process	GO:0031328	316	0.027
response to osmotic stress	GO:0006970	14	0.027
regulation of epithelial cell proliferation	GO:0050678	4	0.027
regulation of epidermal growth factor receptor signaling pathway	GO:0042058	42	0.027
erk1 and erk2 cascade	GO:0070371	39	0.027	Mouse
regulation of phosphorus metabolic process	GO:0051174	210	0.027
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.027
negative regulation of rna metabolic process	GO:0051253	251	0.027
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.027
positive regulation of cellular protein catabolic process	GO:1903364	24	0.027
response to x ray	GO:0010165	8	0.027
regulation of intracellular signal transduction	GO:1902531	236	0.027	Mouse
stem cell differentiation	GO:0048863	117	0.026
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.026
response to peptide hormone	GO:0043434	29	0.026
macromolecule catabolic process	GO:0009057	161	0.026
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.026
response to hypoxia	GO:0001666	53	0.026
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.025
negative regulation of apoptotic process	GO:0043066	63	0.025	Mouse
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.025
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.025
regulation of nurse cell apoptotic process	GO:0045477	9	0.025
mitotic g2 m transition checkpoint	GO:0044818	70	0.025
cellular response to nutrient levels	GO:0031669	62	0.025
neuronal stem cell division	GO:0036445	35	0.024
dorsal ventral pattern formation	GO:0009953	133	0.024
regulation of multicellular organism growth	GO:0040014	40	0.024
negative regulation of protein tyrosine kinase activity	GO:0061099	5	0.024
negative regulation of immune response	GO:0050777	39	0.023
cellular response to nitrogen compound	GO:1901699	51	0.023
embryonic organ development	GO:0048568	50	0.023
asymmetric neuroblast division	GO:0055059	33	0.023
activation of jun kinase activity	GO:0007257	3	0.023
purine nucleoside catabolic process	GO:0006152	112	0.023
regulation of cysteine type endopeptidase activity	GO:2000116	27	0.023	Mouse
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.023
dephosphorylation	GO:0016311	51	0.023
cellular response to hexose stimulus	GO:0071331	1	0.022	Mouse
compound eye development	GO:0048749	307	0.022
decapentaplegic signaling pathway	GO:0008101	19	0.022
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.022
negative regulation of cell differentiation	GO:0045596	143	0.022
regulation of mapk cascade	GO:0043408	92	0.022	Mouse
positive regulation of cellular amine metabolic process	GO:0033240	0	0.021
positive regulation of catabolic process	GO:0009896	105	0.021
regulation of histone acetylation	GO:0035065	7	0.021
positive regulation of protein catabolic process	GO:0045732	34	0.021
chromatin modification	GO:0016568	147	0.021
chitin based cuticle development	GO:0040003	49	0.021
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.021
response to glucose	GO:0009749	2	0.021	Mouse
negative regulation of kinase activity	GO:0033673	16	0.021
membrane invagination	GO:0010324	11	0.021
meiotic nuclear division	GO:0007126	151	0.020
negative regulation of defense response	GO:0031348	35	0.020
negative regulation of developmental growth	GO:0048640	64	0.020
kidney development	GO:0001822	3	0.020
internal peptidyl lysine acetylation	GO:0018393	38	0.020
protein complex localization	GO:0031503	4	0.020
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.020
single organismal cell cell adhesion	GO:0016337	45	0.020
ion homeostasis	GO:0050801	55	0.020
regulation of smoothened signaling pathway	GO:0008589	28	0.019	Zebrafish
regulation of jnk cascade	GO:0046328	40	0.019
autophagy	GO:0006914	108	0.019
regulation of translation	GO:0006417	56	0.019
response to extracellular stimulus	GO:0009991	116	0.019
regulation of neuronal synaptic plasticity	GO:0048168	8	0.019
cytoskeleton dependent cytokinesis	GO:0061640	81	0.019
cuticle pigmentation	GO:0048067	22	0.019
protein deubiquitination	GO:0016579	17	0.019
protein complex assembly	GO:0006461	200	0.019
embryonic axis specification	GO:0000578	107	0.019
cellular response to peptide	GO:1901653	28	0.019
neuromuscular synaptic transmission	GO:0007274	67	0.019
actin filament based process	GO:0030029	220	0.019
negative regulation of canonical wnt signaling pathway	GO:0090090	6	0.019
response to organophosphorus	GO:0046683	2	0.019
dna replication	GO:0006260	48	0.019
positive regulation of molecular function	GO:0044093	136	0.018	Mouse
mitotic cell cycle phase transition	GO:0044772	138	0.018
regulation of mitosis	GO:0007088	56	0.018
histone acetylation	GO:0016573	38	0.018
negative regulation of cell death	GO:0060548	81	0.018	Mouse
negative regulation of epithelial cell proliferation	GO:0050680	4	0.018
response to endogenous stimulus	GO:0009719	119	0.018
multicellular organismal reproductive behavior	GO:0033057	110	0.018
positive regulation of protein modification process	GO:0031401	58	0.018
cilium organization	GO:0044782	41	0.018
regulation of embryonic development	GO:0045995	68	0.018
response to decreased oxygen levels	GO:0036293	58	0.018
chromosome segregation	GO:0007059	157	0.018
chitin based embryonic cuticle biosynthetic process	GO:0008362	16	0.018
imaginal disc pattern formation	GO:0007447	91	0.018

krz disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.026

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