Drosophila melanogaster

250 known processes

CSN5 (Dmel_CG14884)

COP9 complex homolog subunit 5

(Aliases: BcDNA:LD14392,l(3)89Cf,CG14884,csn5,Jab1,Dmel\CG14884,JadBp,JAB1/CSN5,quo,Csn5,Dch5,CH5,l(3)L4032,dch5,BcDNA.LD14392,l(3)M203,jab1/csn5,DCH5)

CSN5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein deneddylationGO:000033880.999
cullin deneddylationGO:001038830.995
axon developmentGO:00615642970.982
negative regulation of cell cycleGO:00457861160.979
negative regulation of mitotic cell cycleGO:00459301090.964
negative regulation of cell cycle phase transitionGO:19019881030.939
oocyte constructionGO:00073081120.938
mitotic g2 m transition checkpointGO:0044818700.928
dna damage checkpointGO:0000077780.916
regulation of cell cycleGO:00517262910.916
regulation of mitotic cell cycleGO:00073461900.911
regulation of cell cycle phase transitionGO:19019871300.911
cell cycle checkpointGO:0000075950.899
oocyte developmentGO:00485991240.865
mitotic dna damage checkpointGO:0044773740.846
regulation of mitotic cell cycle phase transitionGO:19019901300.833
proteolysisGO:00065081920.812
axonogenesisGO:00074092900.812
protein modification processGO:00362114380.812
mitotic g2 dna damage checkpointGO:0007095690.811
mitotic cell cycle checkpointGO:0007093880.805
cell migrationGO:00164772380.798
protein modification by small protein conjugation or removalGO:00706471060.798
g2 dna damage checkpointGO:0031572690.788
negative regulation of gene expressionGO:00106293870.784
negative regulation of cell cycle processGO:00109481090.763
cellular catabolic processGO:00442483720.741
oocyte differentiationGO:00099941450.733
mitotic cell cycle phase transitionGO:00447721380.672
axon guidanceGO:00074112330.647
multicellular organismal reproductive behaviorGO:00330571100.645
oocyte axis specificationGO:00073091080.627
mitotic dna integrity checkpointGO:0044774750.613
reproductive behaviorGO:00190981220.611
regulation of cell cycle processGO:00105641810.606
protein modification by small protein removalGO:0070646280.587
cell maturationGO:00484691440.581
cell motilityGO:00488702510.576
neuron projection guidanceGO:00974852410.575
ubiquitin dependent protein catabolic processGO:0006511780.574
protein catabolic processGO:00301631010.572
axis specificationGO:00097981670.561
posttranscriptional regulation of gene expressionGO:00106081450.550
catabolic processGO:00090564090.535
single organism biosynthetic processGO:00447112060.530
cell cycle phase transitionGO:00447701400.525
multi organism behaviorGO:00517051750.518
meiotic nuclear divisionGO:00071261510.507
cytokinesisGO:0000910900.498
Worm
regulation of programmed cell deathGO:00430671520.495
negative regulation of mitotic cell cycle phase transitionGO:19019911030.487
agingGO:00075681430.471
negative regulation of signal transductionGO:00099682060.457
taxisGO:00423303040.456
nuclear transportGO:0051169720.456
multi organism reproductive behaviorGO:00447051210.445
chromosome organizationGO:00512763600.435
positive regulation of macromolecule metabolic processGO:00106044050.422
male gamete generationGO:00482322010.421
negative regulation of response to stimulusGO:00485852580.416
embryo development ending in birth or egg hatchingGO:00097921520.413
Worm
negative regulation of developmental processGO:00510932010.408
chemotaxisGO:00069352490.402
regulation of cellular localizationGO:00603411360.392
negative regulation of cellular catabolic processGO:0031330340.389
translationGO:0006412690.383
dendrite developmentGO:00163582040.370
regulation of multicellular organismal developmentGO:20000264140.370
dna metabolic processGO:00062592270.358
reproductive structure developmentGO:0048608740.357
Worm
cell divisionGO:00513012480.352
Worm
regulation of cell proliferationGO:00421271630.343
regulation of cellular protein metabolic processGO:00322682430.337
purine nucleoside metabolic processGO:00422781270.336
ncrna metabolic processGO:0034660430.330
protein complex biogenesisGO:00702712010.327
spermatogenesisGO:00072832000.319
columnar cuboidal epithelial cell differentiationGO:00020652560.318
nuclear divisionGO:00002803320.313
oocyte anterior posterior axis specificationGO:0007314720.302
regulation of proteasomal protein catabolic processGO:0061136390.297
eye photoreceptor cell differentiationGO:00017541450.291
modification dependent macromolecule catabolic processGO:0043632790.290
microtubule organizing center organizationGO:00310231680.269
establishment of localization in cellGO:00516494020.261
Human
negative regulation of cellular component organizationGO:00511291080.256
macromolecule catabolic processGO:00090571610.255
negative regulation of cellular metabolic processGO:00313243820.242
endomembrane system organizationGO:00102561190.233
organelle fissionGO:00482853400.232
regulation of cellular component biogenesisGO:00440872010.227
response to organic substanceGO:00100332840.226
positive regulation of gene expressionGO:00106282900.217
Human
protein complex assemblyGO:00064612000.214
meiotic cell cycleGO:00513211710.212
meiotic cell cycle processGO:19030461320.210
negative regulation of macromolecule biosynthetic processGO:00105582700.209
cellular protein modification processGO:00064644380.208
apoptotic processGO:00069151590.206
determination of adult lifespanGO:00083401370.196
cellular macromolecule localizationGO:00707272200.191
chromatin modificationGO:00165681470.190
ovipositionGO:0018991190.190
cellular response to dna damage stimulusGO:00069742230.187
cellular protein catabolic processGO:0044257830.183
positive regulation of rna biosynthetic processGO:19026802660.182
Human
multicellular organismal agingGO:00102591400.177
cell deathGO:00082192790.171
negative regulation of signalingGO:00230572190.169
negative regulation of cell communicationGO:00106482230.167
positive regulation of cellular biosynthetic processGO:00313283160.162
Human
regulation of transportGO:00510491810.162
protein maturationGO:0051604710.159
chromatin organizationGO:00063252070.159
organic substance catabolic processGO:19015753080.157
regulation of localizationGO:00328792750.154
dorsal ventral pattern formationGO:00099531330.153
negative regulation of catabolic processGO:0009895360.153
rna processingGO:00063961470.153
cellular protein localizationGO:00346131600.146
germarium derived egg chamber formationGO:00072931010.145
molting cycle chitin based cuticleGO:0007591560.142
single organism cellular localizationGO:19025801800.138
molting cycleGO:0042303560.136
regulation of protein catabolic processGO:0042176550.135
positive regulation of biosynthetic processGO:00098913160.135
Human
genitalia developmentGO:0048806260.131
Worm
regulation of apoptotic processGO:00429811300.129
cellular response to chemical stimulusGO:00708871990.129
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.127
regulation of intracellular protein transportGO:0033157460.126
covalent chromatin modificationGO:00165691060.126
positive regulation of protein metabolic processGO:00512471280.124
regulation of protein metabolic processGO:00512462560.122
larval developmentGO:00021641040.121
regulation of response to stressGO:00801342000.121
Human
positive regulation of cellular protein metabolic processGO:00322701180.118
locomotory behaviorGO:00076261760.115
protein acetylationGO:0006473390.112
negative regulation of protein processingGO:0010955310.112
nucleocytoplasmic transportGO:0006913720.111
macromolecular complex assemblyGO:00650032560.110
actin filament based processGO:00300292200.110
negative regulation of molecular functionGO:0044092510.108
regulation of cell projection organizationGO:0031344920.106
muscle structure developmentGO:00610612240.104
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051170.101
negative regulation of protein metabolic processGO:0051248850.101
actin filament organizationGO:00070151260.101
modification dependent protein catabolic processGO:0019941780.095
cellular macromolecule catabolic processGO:00442651360.094
organophosphate biosynthetic processGO:0090407460.094
positive regulation of intracellular signal transductionGO:19025331160.091
regulation of proteolysisGO:0030162870.089
nuclear importGO:0051170510.088
regulation of nervous system developmentGO:00519602480.088
regulation of protein dephosphorylationGO:003530450.087
compound eye photoreceptor cell differentiationGO:00017511400.086
actin cytoskeleton organizationGO:00300362060.086
nucleoside metabolic processGO:00091161270.083
negative regulation of programmed cell deathGO:0043069720.082
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.082
morphogenesis of follicular epitheliumGO:0016333360.082
multi multicellular organism processGO:00447061230.080
regionalizationGO:00030024160.079
negative regulation of nitrogen compound metabolic processGO:00511722650.079
protein targeting to nucleusGO:0044744510.079
regulation of cellular protein catabolic processGO:1903362440.078
establishment of protein localizationGO:00451841630.077
histone acetylationGO:0016573380.077
single organism intracellular transportGO:19025822070.076
positive regulation of macromolecule biosynthetic processGO:00105572830.075
Human
dna integrity checkpointGO:0031570810.072
positive regulation of signal transductionGO:00099672230.071
pole plasm mrna localizationGO:0019094490.071
internal protein amino acid acetylationGO:0006475380.070
deathGO:00162652840.070
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:003072260.069
negative regulation of apoptotic processGO:0043066630.067
neurological system processGO:00508773580.067
regulation of cytoplasmic transportGO:1903649470.067
regulation of growthGO:00400082330.066
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.066
negative regulation of nucleobase containing compound metabolic processGO:00459342610.066
negative regulation of protein catabolic processGO:0042177170.064
cuticle developmentGO:0042335860.063
oocyte microtubule cytoskeleton polarizationGO:0008103220.062
negative regulation of multicellular organismal processGO:00512411420.061
epidermal growth factor receptor signaling pathwayGO:0007173580.061
sex differentiationGO:0007548810.061
Worm
regulation of intracellular transportGO:0032386640.060
proteolysis involved in cellular protein catabolic processGO:0051603830.060
developmental maturationGO:00217001720.060
protein transportGO:00150311550.059
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.058
regulation of molecular functionGO:00650092170.058
dendrite morphogenesisGO:00488131990.058
protein localization to nucleusGO:0034504550.058
cytoplasmic transportGO:00164821300.058
cellular macromolecular complex assemblyGO:00346221530.058
ovarian follicle cell developmentGO:00307072480.058
positive regulation of signalingGO:00230562430.057
peptidyl lysine modificationGO:0018205570.056
protein localizationGO:00081042840.056
negative regulation of biosynthetic processGO:00098902770.055
protein localization to organelleGO:0033365820.055
regulation of protein processingGO:0070613320.055
regulation of developmental growthGO:00486381740.055
regulation of protein complex assemblyGO:0043254420.054
regulation of protein localizationGO:0032880760.053
small molecule metabolic processGO:00442813050.053
organic substance transportGO:00717022570.052
learningGO:0007612750.052
regulation of protein import into nucleusGO:0042306280.049
regulation of cell deathGO:00109411730.049
regulation of protein stabilityGO:0031647430.049
negative regulation of cell deathGO:0060548810.049
columnar cuboidal epithelial cell developmentGO:00020662490.048
vesicle mediated transportGO:00161923810.048
Human
single organism nuclear importGO:1902593510.046
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.045
negative regulation of cell differentiationGO:00455961430.045
regulation of neurogenesisGO:00507671580.044
regulation of intracellular signal transductionGO:19025312360.044
Human
cell proliferationGO:00082832990.044
localization of cellGO:00516742570.043
regulation of transcription from rna polymerase ii promoterGO:00063573780.043
Human
dna packagingGO:0006323910.043
rna localizationGO:00064031150.042
gonad developmentGO:0008406500.042
Worm
regulation of organelle organizationGO:00330431960.042
regulation of multi organism processGO:00439001310.041
embryonic axis specificationGO:00005781070.040
regulation of cell developmentGO:00602842150.039
nucleoside catabolic processGO:00091641120.038
regulation of locomotionGO:0040012420.038
negative regulation of protein maturationGO:1903318310.038
organonitrogen compound metabolic processGO:19015643180.037
regulation of establishment of protein localizationGO:0070201610.037
protein phosphorylationGO:00064681690.037
developmental growthGO:00485892800.037
peptidyl amino acid modificationGO:00181931050.036
regulation of protein transportGO:0051223570.036
cellular nitrogen compound catabolic processGO:00442701650.036
development of primary sexual characteristicsGO:0045137500.036
Worm
positive regulation of nucleobase containing compound metabolic processGO:00459353320.036
Human
lateral inhibitionGO:00463312060.036
regulation of protein modification processGO:00313991120.036
positive regulation of cellular component biogenesisGO:0044089800.035
homeostatic processGO:00425921990.035
carbohydrate derivative metabolic processGO:19011352170.035
positive regulation of response to stimulusGO:00485843230.035
negative regulation of protein modification processGO:0031400290.035
transcription from rna polymerase ii promoterGO:00063663680.035
Human
single organism behaviorGO:00447083910.034
phosphorylationGO:00163102940.034
Human
regulation of nucleocytoplasmic transportGO:0046822350.033
imaginal disc derived wing morphogenesisGO:00074763370.033
amine metabolic processGO:0009308120.033
instar larval developmentGO:0002168550.032
regulation of dna templated transcription elongationGO:0032784170.032
appendage developmentGO:00487364010.032
chromatin remodelingGO:0006338720.031
establishment or maintenance of cytoskeleton polarityGO:0030952440.031
regulation of neuron differentiationGO:00456641030.031
positive regulation of phosphate metabolic processGO:00459371390.030
programmed cell deathGO:00125012570.030
female germ line stem cell asymmetric divisionGO:0048132140.030
body morphogenesisGO:001017120.030
negative regulation of cellular protein metabolic processGO:0032269850.030
protein ubiquitinationGO:0016567700.029
transmembrane transportGO:00550851390.029
negative regulation of proteasomal protein catabolic processGO:1901799160.029
ribonucleoprotein complex subunit organizationGO:0071826280.029
epithelial cell differentiationGO:00308553220.028
protein modification by small protein conjugationGO:0032446790.028
regulation of anatomical structure sizeGO:00900661630.028
response to abiotic stimulusGO:00096283410.028
regulation of protein maturationGO:1903317320.028
ion transmembrane transportGO:00342201220.027
response to hypoxiaGO:0001666530.027
positive regulation of rna metabolic processGO:00512542710.027
Human
regulation of cell morphogenesis involved in differentiationGO:0010769610.027
positive regulation of phosphorylationGO:0042327870.026
cellular response to organic substanceGO:00713101320.026
imaginal disc derived appendage morphogenesisGO:00351143950.026
negative regulation of cellular biosynthetic processGO:00313272770.025
regulation of protein phosphorylationGO:0001932640.025
stem cell developmentGO:0048864790.024
defense response to bacteriumGO:00427421780.024
oxidation reduction processGO:00551141230.024
organic acid metabolic processGO:00060821030.024
positive regulation of neurogenesisGO:0050769410.024
intracellular transportGO:00469072280.023
border follicle cell migrationGO:00072981130.023
histone modificationGO:00165701060.023
central nervous system developmentGO:00074172010.023
positive regulation of transportGO:0051050920.023
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.023
Human
cellular amine metabolic processGO:0044106120.023
cellular response to oxygen containing compoundGO:1901701790.022
nucleobase containing compound catabolic processGO:00346551650.022
anterior posterior pattern specificationGO:00099521360.022
ribonucleoprotein complex biogenesisGO:0022613310.022
negative regulation of nucleic acid templated transcriptionGO:19035072400.021
carbohydrate derivative catabolic processGO:19011361180.021
organic cyclic compound catabolic processGO:19013611680.021
negative regulation of organelle organizationGO:0010639560.021
eye morphogenesisGO:00485922600.021
establishment or maintenance of cell polarityGO:00071631670.020
ovarian follicle cell migrationGO:00072971210.020
centrosome organizationGO:00512971630.020
negative regulation of rna biosynthetic processGO:19026792400.020
dna replicationGO:0006260480.020
organelle assemblyGO:00709251980.020
positive regulation of cell communicationGO:00106472500.020
purine ribonucleoside triphosphate catabolic processGO:00092071080.020
regulation of translationGO:0006417560.019
negative regulation of proteolysisGO:0045861310.019
maternal determination of anterior posterior axis embryoGO:0008358740.019
muscle organ developmentGO:00075171270.019
regulation of dna replicationGO:0006275130.019
cell cell signaling involved in cell fate commitmentGO:00451682100.019
lipid biosynthetic processGO:0008610460.018
atp catabolic processGO:0006200380.018
response to radiationGO:00093141550.018
stem cell divisionGO:0017145690.018
regulation of kinase activityGO:0043549530.018
cellular ketone metabolic processGO:0042180240.018
organonitrogen compound biosynthetic processGO:19015661170.017
cytoskeleton dependent cytokinesisGO:0061640810.017
positive regulation of apoptotic signaling pathwayGO:200123540.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.017
positive regulation of nucleic acid templated transcriptionGO:19035082660.017
Human
enzyme linked receptor protein signaling pathwayGO:00071671790.017
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.016
reproductive system developmentGO:0061458740.016
Worm
appendage morphogenesisGO:00351073970.016
cell agingGO:000756920.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.016
growthGO:00400073590.016
membrane organizationGO:00610241120.016
intracellular protein transportGO:00068861040.016
positive regulation of protein modification processGO:0031401580.016
positive regulation of intracellular transportGO:0032388420.016
positive regulation of cell proliferationGO:0008284470.016
germarium derived female germ line cyst formationGO:0030727420.016
organophosphate metabolic processGO:00196371950.016
ovarian follicle cell stalk formationGO:0030713170.016
germ cell migrationGO:0008354430.016
organelle localizationGO:00516401480.015
regulation of chromosome segregationGO:0051983320.015
autophagic vacuole assemblyGO:000004520.015
proteasomal protein catabolic processGO:0010498590.015
purine nucleotide metabolic processGO:00061631460.015
mrna processingGO:00063971040.015
smoothened signaling pathwayGO:0007224490.015
purine ribonucleoside catabolic processGO:00461301120.015
establishment of protein localization to organelleGO:0072594620.015
microtubule cytoskeleton organization involved in mitosisGO:1902850520.015
positive regulation of phosphorus metabolic processGO:00105621390.014
heterocycle catabolic processGO:00467001660.014
response to endogenous stimulusGO:00097191190.014
negative regulation of stem cell proliferationGO:2000647300.014
positive regulation of apoptotic processGO:0043065470.014
stem cell differentiationGO:00488631170.014
cellular homeostasisGO:0019725800.014
regulation of cellular response to stressGO:0080135890.014
Human
regulation of cdc42 protein signal transductionGO:003248930.014
response to temperature stimulusGO:00092661060.014
regulation of cellular ketone metabolic processGO:001056530.014
epithelial cell migrationGO:00106311480.014
positive regulation of transcription dna templatedGO:00458932660.013
Human
striated muscle myosin thick filament assemblyGO:007168830.013
negative regulation of transcription dna templatedGO:00458922370.013
synaptic growth at neuromuscular junctionGO:00511241190.013
response to oxygen containing compoundGO:19017002000.013
glycosyl compound catabolic processGO:19016581120.013
negative regulation of phosphate metabolic processGO:0045936450.013
cellular component disassemblyGO:0022411460.012
purine containing compound metabolic processGO:00725211550.012
oocyte dorsal ventral axis specificationGO:0007310340.012
regulation of homotypic cell cell adhesionGO:003411020.012
chitin based cuticle developmentGO:0040003490.012
cellular response to growth factor stimulusGO:0071363300.012
internal peptidyl lysine acetylationGO:0018393380.012
ribonucleoside triphosphate metabolic processGO:00091991190.012
response to organic cyclic compoundGO:0014070890.012
wing disc morphogenesisGO:00074723440.012
positive regulation of developmental processGO:00510941430.012
ribonucleotide catabolic processGO:00092611090.012
mitotic cytokinesisGO:0000281500.012
regulation of phosphorylationGO:00423251470.012
Human
regulation of cell differentiationGO:00455953020.012
germarium derived oocyte fate determinationGO:0007294260.012
ncrna processingGO:0034470300.011
protein processingGO:0016485680.011
pole plasm assemblyGO:0007315610.011
negative regulation of immune system processGO:0002683500.011
carbohydrate metabolic processGO:0005975820.011
positive regulation of protein phosphorylationGO:0001934340.011
regulation of gene expression epigeneticGO:00400291280.011
purine nucleoside triphosphate metabolic processGO:00091441190.011
connective tissue developmentGO:006144830.011
regulation of pole plasm oskar mrna localizationGO:0007317270.011
regulation of neuron deathGO:1901214260.011
protein secretionGO:0009306450.011
compound eye developmentGO:00487493070.011
intracellular signal transductionGO:00355563000.011
Human
negative regulation of catalytic activityGO:0043086420.011
positive regulation of multicellular organismal processGO:00512401430.011
germarium derived female germ line cyst encapsulationGO:003070880.011
nucleoside triphosphate metabolic processGO:00091411200.011
regulation of phosphorus metabolic processGO:00511742100.011
Human
negative regulation of neuroblast proliferationGO:0007406270.010
protein import into nucleusGO:0006606510.010
regulation of microtubule based processGO:0032886490.010
gene silencing by rnaGO:0031047570.010
negative regulation of protein phosphorylationGO:0001933170.010
glycosyl compound metabolic processGO:19016571270.010
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.010
oxoacid metabolic processGO:00434361030.010
mesenchymal cell developmentGO:001403110.010
negative regulation of intracellular signal transductionGO:1902532570.010

CSN5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.012
muscular diseaseDOID:008000000.012
disease of anatomical entityDOID:700.012
myopathyDOID:42300.012
muscle tissue diseaseDOID:6600.012
disease of cellular proliferationDOID:1456600.010