Drosophila melanogaster

74 known processes

Jafrac1 (Dmel_CG1633)

thioredoxin peroxidase 1

(Aliases: cTPx,1633,CG1633,SSP5111,T20,jafrac1,DPx4783,dPrx I,Prx4783,Dmel\CG1633,DPx-4783,Prx,DmTPx-1)

Jafrac1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062592270.958
Yeast
response to oxidative stressGO:0006979860.885
cellular response to oxidative stressGO:0034599280.769
response to external biotic stimulusGO:00432072930.768
Fly
cellular response to dna damage stimulusGO:00069742230.762
response to radiationGO:00093141550.690
response to bacteriumGO:00096171980.675
Fly
response to other organismGO:00517072930.642
Fly
organic acid metabolic processGO:00060821030.619
response to biotic stimulusGO:00096072940.576
Fly
cellular catabolic processGO:00442483720.568
organonitrogen compound metabolic processGO:19015643180.537
small molecule metabolic processGO:00442813050.525
defense responseGO:00069523000.485
Fly
positive regulation of nitrogen compound metabolic processGO:00511733540.467
catabolic processGO:00090564090.439
response to reactive oxygen speciesGO:0000302240.366
defense response to other organismGO:00985422250.359
Fly
peptide metabolic processGO:0006518800.355
positive regulation of biosynthetic processGO:00098913160.340
defense response to bacteriumGO:00427421780.330
Fly
positive regulation of cellular biosynthetic processGO:00313283160.304
response to extracellular stimulusGO:00099911160.302
apoptotic signaling pathwayGO:0097190270.289
Fly
negative regulation of cellular metabolic processGO:00313243820.285
response to hydrogen peroxideGO:0042542110.282
determination of adult lifespanGO:00083401370.279
agingGO:00075681430.273
regulation of response to stressGO:00801342000.266
defense response to gram negative bacteriumGO:0050829940.263
regulation of transcription from rna polymerase ii promoterGO:00063573780.235
establishment of localization in cellGO:00516494020.228
negative regulation of gene expressionGO:00106293870.226
response to light stimulusGO:00094161240.212
positive regulation of nucleobase containing compound metabolic processGO:00459353320.210
cellular modified amino acid metabolic processGO:0006575450.209
oxoacid metabolic processGO:00434361030.209
deathGO:00162652840.204
Fly
dna repairGO:0006281540.200
regulation of localizationGO:00328792750.197
nuclear divisionGO:00002803320.187
response to inorganic substanceGO:0010035440.184
organic substance catabolic processGO:19015753080.182
response to abiotic stimulusGO:00096283410.179
Fly
glycosyl compound metabolic processGO:19016571270.176
organophosphate metabolic processGO:00196371950.175
cellular ketone metabolic processGO:0042180240.172
positive regulation of macromolecule metabolic processGO:00106044050.164
Fly
localization of cellGO:00516742570.162
negative regulation of biosynthetic processGO:00098902770.159
organonitrogen compound biosynthetic processGO:19015661170.155
chromosome organizationGO:00512763600.150
cognitionGO:00508901410.149
cellular response to chemical stimulusGO:00708871990.146
positive regulation of macromolecule biosynthetic processGO:00105572830.146
cell motilityGO:00488702510.144
cellular amide metabolic processGO:0043603800.140
response to nutrient levelsGO:00316671140.134
neurological system processGO:00508773580.130
chromatin organizationGO:00063252070.130
cell deathGO:00082192790.129
Fly
positive regulation of immune responseGO:0050778630.126
response to ionizing radiationGO:0010212320.124
endocytosisGO:00068973100.123
Fly
lipid metabolic processGO:00066291210.123
immune system processGO:00023763470.120
regulation of immune responseGO:00507761180.117
cellular amino acid metabolic processGO:0006520610.116
single organism behaviorGO:00447083910.115
circulatory system developmentGO:0072359820.115
male gamete generationGO:00482322010.114
axon developmentGO:00615642970.105
response to oxygen radicalGO:000030530.103
homeostatic processGO:00425921990.101
muscle system processGO:0003012210.100
regulation of tube sizeGO:0035150460.098
taxisGO:00423303040.098
wound healingGO:0042060750.096
response to metal ionGO:0010038230.095
meiotic cell cycleGO:00513211710.093
positive regulation of multicellular organismal processGO:00512401430.092
positive regulation of programmed cell deathGO:0043068620.091
Fly
negative regulation of transcription dna templatedGO:00458922370.091
nucleobase containing compound catabolic processGO:00346551650.090
regulation of catabolic processGO:00098941700.090
transcription from rna polymerase ii promoterGO:00063663680.087
cardiovascular system developmentGO:0072358820.086
regulation of proteolysisGO:0030162870.086
Fly
regulation of innate immune responseGO:0045088710.085
response to endogenous stimulusGO:00097191190.085
protein complex biogenesisGO:00702712010.084
brain developmentGO:00074201200.084
organelle fissionGO:00482853400.084
cellular amine metabolic processGO:0044106120.084
intracellular signal transductionGO:00355563000.084
Fly
regulation of cell deathGO:00109411730.083
Fly
cellular nitrogen compound catabolic processGO:00442701650.081
regulation of defense responseGO:00313471020.079
regulation of cell developmentGO:00602842150.079
multicellular organismal agingGO:00102591400.077
vesicle mediated transportGO:00161923810.076
Fly
ribonucleoside triphosphate metabolic processGO:00091991190.075
developmental pigmentationGO:0048066680.075
negative regulation of nucleobase containing compound metabolic processGO:00459342610.074
single organism biosynthetic processGO:00447112060.074
amine metabolic processGO:0009308120.073
cell agingGO:000756920.072
Yeast
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.072
intracellular transportGO:00469072280.071
dendrite developmentGO:00163582040.071
apoptotic processGO:00069151590.070
Fly
sulfur compound metabolic processGO:0006790590.070
carboxylic acid metabolic processGO:0019752920.069
regulation of multicellular organismal developmentGO:20000264140.069
central nervous system developmentGO:00074172010.067
spermatogenesisGO:00072832000.066
protein targeting to nucleusGO:0044744510.066
dna damage checkpointGO:0000077780.066
Yeast
reactive oxygen species metabolic processGO:0072593220.065
response to organic substanceGO:00100332840.064
regulation of neuron deathGO:1901214260.063
positive regulation of rna biosynthetic processGO:19026802660.063
larval developmentGO:00021641040.062
positive regulation of cell deathGO:0010942690.062
Fly
protein complex assemblyGO:00064612000.062
positive regulation of rna metabolic processGO:00512542710.062
muscle tissue developmentGO:0060537300.061
regulation of transportGO:00510491810.061
growthGO:00400073590.061
regulation of hydrolase activityGO:0051336970.060
Fly
macromolecular complex assemblyGO:00650032560.059
muscle contractionGO:0006936130.058
positive regulation of catalytic activityGO:00430851180.058
Fly
regulation of peptidase activityGO:0052547390.057
Fly
positive regulation of cell migrationGO:003033520.057
epithelial cell differentiationGO:00308553220.056
protein modification processGO:00362114380.056
regulation of cellular catabolic processGO:00313291570.056
single organism cellular localizationGO:19025801800.056
regulation of growthGO:00400082330.055
epidermal cell differentiationGO:0009913510.053
cellular component assembly involved in morphogenesisGO:00109271510.052
organelle assemblyGO:00709251980.052
regulation of catalytic activityGO:00507901850.052
Fly
positive regulation of signal transductionGO:00099672230.052
Fly
negative regulation of developmental processGO:00510932010.052
respiratory system developmentGO:00605412130.051
regulation of immune system processGO:00026821760.051
positive regulation of transcription dna templatedGO:00458932660.050
positive regulation of response to stimulusGO:00485843230.050
Fly
glutathione metabolic processGO:0006749370.050
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.049
Fly
cellular response to organic substanceGO:00713101320.049
regulation of intracellular signal transductionGO:19025312360.049
Fly
muscle structure developmentGO:00610612240.049
heterocycle catabolic processGO:00467001660.049
protein phosphorylationGO:00064681690.048
innate immune responseGO:00450871440.048
regulation of cellular ketone metabolic processGO:001056530.048
regulation of response to external stimulusGO:00321011150.047
response to starvationGO:0042594970.047
response to heatGO:0009408630.047
sex differentiationGO:0007548810.047
aromatic compound catabolic processGO:00194391660.047
single organism catabolic processGO:00447122280.047
anatomical structure homeostasisGO:0060249970.047
regulation of anatomical structure sizeGO:00900661630.047
immune responseGO:00069552460.046
positive regulation of nucleic acid templated transcriptionGO:19035082660.046
striated muscle tissue developmentGO:0014706270.045
embryo development ending in birth or egg hatchingGO:00097921520.045
cellular lipid metabolic processGO:0044255830.044
actin cytoskeleton organizationGO:00300362060.044
negative regulation of cellular biosynthetic processGO:00313272770.043
positive regulation of cellular component organizationGO:00511301560.043
forebrain developmentGO:003090020.042
response to oxygen containing compoundGO:19017002000.042
organic cyclic compound catabolic processGO:19013611680.042
peptidyl amino acid modificationGO:00181931050.042
positive regulation of cellular catabolic processGO:0031331950.041
muscle cell developmentGO:0055001500.041
response to woundingGO:0009611940.041
response to lipopolysaccharideGO:003249640.040
regulation of anatomical structure morphogenesisGO:00226032420.040
oxidation reduction processGO:00551141230.039
positive regulation of molecular functionGO:00440931360.038
Fly
negative regulation of nitrogen compound metabolic processGO:00511722650.038
protein importGO:0017038550.038
cellular macromolecule localizationGO:00707272200.037
pigmentationGO:0043473750.037
cellular response to ionizing radiationGO:0071479150.037
striated muscle cell differentiationGO:0051146900.037
negative regulation of response to stimulusGO:00485852580.037
negative regulation of signalingGO:00230572190.037
cell migrationGO:00164772380.036
negative regulation of apoptotic processGO:0043066630.036
Fly
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.036
proteolysisGO:00065081920.035
Fly
negative regulation of phosphate metabolic processGO:0045936450.035
protein localization to nucleusGO:0034504550.035
skin developmentGO:0043588650.035
regulation of cellular response to stressGO:0080135890.034
developmental programmed cell deathGO:00106231380.034
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.034
Fly
regulation of apoptotic processGO:00429811300.034
Fly
cellular protein modification processGO:00064644380.034
negative regulation of signal transductionGO:00099682060.034
cellular macromolecular complex assemblyGO:00346221530.034
reproductive structure developmentGO:0048608740.033
chemotaxisGO:00069352490.033
response to lipidGO:0033993380.033
meiotic nuclear divisionGO:00071261510.032
phosphorylationGO:00163102940.032
connective tissue developmentGO:006144830.032
open tracheal system developmentGO:00074242040.032
purine nucleoside triphosphate metabolic processGO:00091441190.031
regulation of dna metabolic processGO:0051052340.031
intrinsic apoptotic signaling pathwayGO:0097193160.031
positive regulation of hydrolase activityGO:0051345780.030
Fly
regulation of cellular localizationGO:00603411360.030
negative regulation of immune system processGO:0002683500.029
mitochondrion organizationGO:0007005650.029
response to transition metal nanoparticleGO:199026790.029
regulation of phosphate metabolic processGO:00192202100.029
negative regulation of rna biosynthetic processGO:19026792400.029
ion transportGO:00068111450.029
regulation of apoptotic signaling pathwayGO:2001233100.028
Fly
response to superoxideGO:000030330.028
embryonic organ developmentGO:0048568500.027
mitotic nuclear divisionGO:00070672130.027
ribonucleoside metabolic processGO:00091191270.027
positive regulation of immune system processGO:0002684680.027
purine ribonucleoside triphosphate metabolic processGO:00092051190.027
negative regulation of programmed cell deathGO:0043069720.027
Fly
organic substance transportGO:00717022570.027
negative regulation of rna metabolic processGO:00512532510.027
immune system developmentGO:0002520570.027
regulation of protein metabolic processGO:00512462560.026
Fly
establishment of protein localizationGO:00451841630.026
purine ribonucleoside metabolic processGO:00461281270.026
purine nucleoside metabolic processGO:00422781270.026
positive regulation of catabolic processGO:00098961050.026
dendrite morphogenesisGO:00488131990.026
phagocytosisGO:00069092150.026
Fly
negative regulation of cell deathGO:0060548810.026
Fly
positive regulation of reactive oxygen species metabolic processGO:200037900.026
response to temperature stimulusGO:00092661060.026
Fly
nucleotide catabolic processGO:00091661090.026
purine nucleotide metabolic processGO:00061631460.025
organophosphate catabolic processGO:00464341120.025
regulation of cellular amine metabolic processGO:003323830.025
heart morphogenesisGO:0003007320.025
nucleobase containing small molecule metabolic processGO:00550861740.024
protein import into nucleusGO:0006606510.024
positive regulation of cell differentiationGO:0045597640.024
programmed cell deathGO:00125012570.024
Fly
establishment of protein localization to organelleGO:0072594620.023
cellular response to metal ionGO:007124860.023
purine ribonucleotide catabolic processGO:00091541090.023
negative regulation of phosphorylationGO:0042326350.023
secondary metabolic processGO:0019748750.023
regulation of organelle organizationGO:00330431960.023
embryonic pattern specificationGO:00098801740.023
cation transportGO:00068121100.022
purine nucleoside triphosphate catabolic processGO:00091461080.022
development of primary sexual characteristicsGO:0045137500.022
positive regulation of phosphorus metabolic processGO:00105621390.021
telencephalon developmentGO:002153720.021
single organism carbohydrate metabolic processGO:0044723720.021
cellular protein localizationGO:00346131600.021
axon guidanceGO:00074112330.021
regulation of protein modification processGO:00313991120.020
regulation of cell differentiationGO:00455953020.020
positive regulation of developmental growthGO:0048639620.020
regulation of cellular component biogenesisGO:00440872010.020
positive regulation of intracellular signal transductionGO:19025331160.020
Fly
spermatid developmentGO:0007286980.020
negative regulation of macromolecule biosynthetic processGO:00105582700.019
neuron deathGO:0070997270.019
cellular homeostasisGO:0019725800.019
regulation of cell cycleGO:00517262910.019
gonad developmentGO:0008406500.019
positive regulation of developmental processGO:00510941430.019
regulation of cellular response to oxidative stressGO:190040740.019
heart developmentGO:0007507820.019
response to glucoseGO:000974920.019
regulation of chemotaxisGO:0050920120.019
negative regulation of cell cycleGO:00457861160.019
dna replicationGO:0006260480.019
generation of precursor metabolites and energyGO:0006091420.018
dephosphorylationGO:0016311510.018
nucleoside phosphate metabolic processGO:00067531620.018
regulation of cysteine type endopeptidase activityGO:2000116270.018
Fly
positive regulation of gene expressionGO:00106282900.018
nucleocytoplasmic transportGO:0006913720.018
protein targetingGO:0006605640.018
transmembrane transportGO:00550851390.018
negative regulation of defense responseGO:0031348350.018
ribose phosphate metabolic processGO:00196931450.017
centrosome cycleGO:00070981370.017
ribonucleotide catabolic processGO:00092611090.017
regulation of cellular protein metabolic processGO:00322682430.017
Fly
digestive tract morphogenesisGO:00485461270.017
tube developmentGO:00352952440.017
epithelial cell developmentGO:00020642740.017
nitrogen compound transportGO:0071705850.017
appendage developmentGO:00487364010.017
positive regulation of cellular protein metabolic processGO:00322701180.017
Fly
negative regulation of cell communicationGO:00106482230.017
camera type eye developmentGO:004301040.017
muscle organ developmentGO:00075171270.017
head developmentGO:00603221350.017
response to hormoneGO:0009725450.017
negative regulation of cell differentiationGO:00455961430.016
carbohydrate metabolic processGO:0005975820.016
ribonucleoprotein complex assemblyGO:0022618230.016
autophagyGO:00069141080.016
reproductive system developmentGO:0061458740.016
purine ribonucleotide metabolic processGO:00091501450.016
negative regulation of protein modification processGO:0031400290.016
dna recombinationGO:0006310320.016
chromatin modificationGO:00165681470.016
mitotic spindle organizationGO:00070522200.016
negative regulation of protein metabolic processGO:0051248850.016
positive regulation of purine nucleotide catabolic processGO:0033123460.016
purine containing compound metabolic processGO:00725211550.016
protein localizationGO:00081042840.015
salivary gland developmentGO:00074311620.015
regulation of phosphorus metabolic processGO:00511742100.015
segmentationGO:00352822070.015
regulation of neuron apoptotic processGO:0043523160.015
regulation of molecular functionGO:00650092170.015
Fly
nuclear importGO:0051170510.015
positive regulation of cysteine type endopeptidase activityGO:2001056240.015
Fly
single organism intracellular transportGO:19025822070.015
nucleoside triphosphate catabolic processGO:00091431080.015
stress activated mapk cascadeGO:0051403520.015
dna integrity checkpointGO:0031570810.015
Yeast
regulation of antimicrobial humoral responseGO:0002759500.015
axonogenesisGO:00074092900.014
cellular biogenic amine catabolic processGO:004240210.014
cellular response to oxygen containing compoundGO:1901701790.014
enzyme linked receptor protein signaling pathwayGO:00071671790.014
ovarian follicle cell developmentGO:00307072480.014
myofibril assemblyGO:0030239360.014
regulation of nucleotide metabolic processGO:0006140620.014
locomotory behaviorGO:00076261760.014
organonitrogen compound catabolic processGO:19015651280.014
tissue homeostasisGO:0001894360.014
purine nucleotide catabolic processGO:00061951090.014
positive regulation of phosphate metabolic processGO:00459371390.014
epithelial cell migrationGO:00106311480.014
glycosyl compound catabolic processGO:19016581120.014
maintenance of locationGO:0051235730.014
positive regulation of apoptotic processGO:0043065470.014
Fly
positive regulation of apoptotic signaling pathwayGO:200123540.014
Fly
negative regulation of protein phosphorylationGO:0001933170.014
anterior posterior axis specification embryoGO:00085951030.014
striated muscle cell developmentGO:0055002500.014
negative regulation of molecular functionGO:0044092510.013
meiotic cell cycle processGO:19030461320.013
purine nucleoside monophosphate metabolic processGO:0009126500.013
nucleotide metabolic processGO:00091171610.013
small molecule biosynthetic processGO:0044283370.013
purine ribonucleoside catabolic processGO:00461301120.013
atp metabolic processGO:0046034490.013
regulation of programmed cell deathGO:00430671520.013
Fly
positive regulation of cell proliferationGO:0008284470.013
regulation of response to oxidative stressGO:190288240.013
negative regulation of nucleic acid templated transcriptionGO:19035072400.013
negative regulation of multicellular organismal processGO:00512411420.013
response to nitrogen compoundGO:1901698900.013
immune response activating signal transductionGO:000275720.013
macromolecule catabolic processGO:00090571610.013
actin filament based processGO:00300292200.013
tripartite regional subdivisionGO:00073511030.013
regulation of reactive oxygen species metabolic processGO:200037780.013
regulation of dna replicationGO:0006275130.013
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.013
embryonic morphogenesisGO:00485982060.012
nucleoside triphosphate metabolic processGO:00091411200.012
axis specificationGO:00097981670.012
rna splicingGO:0008380830.012
regulation of i kappab kinase nf kappab signalingGO:004312220.012
imaginal disc derived appendage morphogenesisGO:00351143950.012
organic hydroxy compound catabolic processGO:190161640.012
detection of stimulusGO:00516061560.012
nucleotide excision repairGO:000628980.012
posttranscriptional regulation of gene expressionGO:00106081450.012
ribonucleoside triphosphate catabolic processGO:00092031080.012
positive regulation of transportGO:0051050920.012
humoral immune responseGO:00069591170.012
nucleoside catabolic processGO:00091641120.012
negative regulation of phosphorus metabolic processGO:0010563450.012
regulation of mapk cascadeGO:0043408920.012
regulation of nervous system developmentGO:00519602480.012
female meiotic divisionGO:0007143700.012
purine containing compound catabolic processGO:00725231120.011
sensory perceptionGO:00076001960.011
regulation of behaviorGO:0050795750.011
mrna metabolic processGO:00160711240.011
compound eye developmentGO:00487493070.011
regulation of mrna metabolic processGO:1903311720.011
mapk cascadeGO:00001651070.011
positive regulation of defense responseGO:0031349590.011
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.011
regulation of ras protein signal transductionGO:0046578930.011
organophosphate biosynthetic processGO:0090407460.011
carbohydrate derivative metabolic processGO:19011352170.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.011
purine nucleoside catabolic processGO:00061521120.011
learning or memoryGO:00076111410.011
regulation of autophagyGO:0010506620.011
eye pigment metabolic processGO:0042441330.011
response to molecule of bacterial originGO:000223770.011
regulation of protein localizationGO:0032880760.011
cytoplasmic transportGO:00164821300.011
regulation of nucleoside metabolic processGO:0009118500.011
positive regulation of signalingGO:00230562430.011
Fly
response to organic cyclic compoundGO:0014070890.011
positive regulation of growthGO:0045927750.010
tissue morphogenesisGO:00487292970.010
ribonucleotide metabolic processGO:00092591450.010
nucleoside phosphate catabolic processGO:19012921100.010
male sex differentiationGO:0046661250.010
cellular response to nitrogen compoundGO:1901699510.010
glycosyl compound biosynthetic processGO:190165930.010
positive regulation of cell motilityGO:200014730.010
digestive tract developmentGO:00485651490.010
regulation of purine nucleotide catabolic processGO:0033121480.010
imaginal disc derived wing morphogenesisGO:00074763370.010
regulation of neurogenesisGO:00507671580.010

Jafrac1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.244
cancerDOID:16200.062
disease of cellular proliferationDOID:1456600.062
organ system cancerDOID:005068600.052
nervous system diseaseDOID:86300.034
musculoskeletal system diseaseDOID:1700.021
sensory system diseaseDOID:005015500.020